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WO2020116882A1 - Ophthalmic ultrasonic treatment device using image scanning method - Google Patents

Ophthalmic ultrasonic treatment device using image scanning method Download PDF

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Publication number
WO2020116882A1
WO2020116882A1 PCT/KR2019/016864 KR2019016864W WO2020116882A1 WO 2020116882 A1 WO2020116882 A1 WO 2020116882A1 KR 2019016864 W KR2019016864 W KR 2019016864W WO 2020116882 A1 WO2020116882 A1 WO 2020116882A1
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Prior art keywords
ultrasound
image scanning
unit
image
ultrasonic
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PCT/KR2019/016864
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French (fr)
Korean (ko)
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송수형
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36046Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0245Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with ultrasonic transducers, e.g. piezoelectric
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H5/00Exercisers for the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0543Retinal electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/10Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00Devices for specific parts of the body
    • A61H2205/02Head
    • A61H2205/022Face
    • A61H2205/024Eyes

Definitions

  • the present invention relates to an ultrasound treatment apparatus for ophthalmology, and more particularly, to an ultrasound treatment apparatus for ophthalmology that scans the eye condition through initial ultrasound examination and controls to irradiate ultrasound for eye treatment based on the acquired image data. will be.
  • Presbyopia refers to a condition in which the function of the lens decreases due to aging of the body, and thus it is unable to focus at close range. It usually occurs after the age of 40, but in modern times, the number of cases occurring around the 30s is gradually increasing due to frequent short-term work such as the use of mobile phones and PCs.
  • Ultrasound is an acoustic pressure wave having a frequency above a human hearing range (16 Hz to 20 kHz), and is a form of mechanical energy transmitted through biological tissue.
  • therapeutic ultrasound is used in various ways according to the purpose, purpose, and characteristics of treatment using three physical effects: mechanical effect, resonance effect, and thermal effect.
  • the treatment device or method using ultrasound has the advantage that it can be performed non-invasively without surgical procedures and has a fast recovery time, so it is actively spread not only in Korea but also worldwide.
  • the present invention is to solve the problems of the above-described prior art, the object of the present invention is to obtain data on the patient's eye state by image scanning method based on it to control the ultrasound treatment conditions and / or re-treatment for ophthalmology It is to provide an ultrasonic treatment device.
  • One aspect of the present invention is a base film portion; A cover film part overlapping all or part of the base film part; An ultrasonic element portion formed of a plurality of elements spaced apart at a predetermined distance between the base film portion and the cover film portion, and transmitting/receiving ultrasonic waves in the eyeball direction; A power supply unit supplying power to the ultrasonic element unit; A control operation unit for controlling the ultrasonic element unit; And a connector part electrically connecting the ultrasonic element part to the control operation part and the power supply part.
  • the ultrasonic element portion includes a first element portion for irradiating ultrasound for treatment; A second element unit for transmitting and receiving ultrasound for image scanning; And an ultrasonic converter for converting electrical energy into physical energy or converting physical energy into electrical energy within an ultrasonic frequency range, wherein the control operation unit receives the scan information from the second device unit and receives the first device. It may be to set a control element for irradiating ultrasound for treatment.
  • the second element unit an image transmission unit for transmitting an ultrasound signal for image scanning for the eyeball; Transistor for converting the transmission signal of the ultrasound to the eye to the received signal; And an image receiving unit receiving an ultrasound signal for image scanning from the eyeball.
  • the image transmission unit a transmission beam former for generating a transmission ultrasound beam for image scanning; A second pulse generator that generates vibrations in the transmission ultrasound for image scanning; A transmission low pass filter for passing only frequency signals below a predetermined frequency in the transmission ultrasound for image scanning; And a second amplifier that amplifies the transmission ultrasound for image scanning.
  • the image receiving unit a low-noise amplifier designed to minimize noise in the signal of the received ultrasound for image scanning; A voltage adjustment attenuator for adjusting the voltage of the received ultrasound signal for image scanning; A reception low pass filter for passing only frequency signals below a predetermined frequency in the reception ultrasound for image scanning; An A/D converter that converts the received ultrasound for image scanning from an analog signal to a digital signal; And a reception beam former that generates an ultrasound beam for image scanning and provides the control beam to the control operation unit.
  • the first device unit a therapeutic beam forming machine of therapeutic ultrasound to generate an ultrasound beam for eye treatment;
  • a first pulse generator that generates vibrations in the therapeutic ultrasound;
  • a first amplifier to amplify the therapeutic ultrasound;
  • the therapeutic ultrasound may be a low intensity focused ultrasound.
  • control operation unit calculates the presbyopia position and degree of lens presbyopia of the eye using the scan information received from the second device unit, and the focus area and focus area of the ultrasound for treatment by the first device unit are irradiated. Controlling any one or more of intensity, pulse repetition period, pulse width, acoustic operating frequency, irradiation time, and focal length, but independently adjusting the arrival times of control signals for a plurality of elements with respect to the first element part Can be.
  • the present invention by obtaining images and various data on the presbyopia position and level of the patient's lens, and setting ultrasound treatment conditions accordingly, it is possible to enable precise and efficient ultrasound treatment according to the ocular environment of various patients. have.
  • the system checks the effect of the ultrasound treatment and checks for re-treatment, thereby observing the eyeballs of particularly sensitive areas of the human body. The completeness of the treatment can be ensured.
  • FIG. 1 is a front view of an ophthalmic ultrasound therapy apparatus using an image scanning method according to an embodiment of the present invention.
  • FIG. 2 is an exploded perspective view of the ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 1.
  • FIG. 3 is a perspective view of the ophthalmic ultrasound therapy apparatus using the image scanning method of FIG. 2 in a connected state with a control operation unit.
  • FIG. 4 is a state diagram of the use of the ophthalmic ultrasound therapy apparatus using the image scanning method of FIG. 3.
  • FIG. 5 is a block diagram showing the mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.
  • FIG. 6 is a block diagram showing a mechanism of an ophthalmic ultrasound therapy apparatus using an image scanning method in which signals are independently transmitted to a plurality of devices according to an embodiment of the present invention.
  • FIG. 7 is a schematic diagram showing a form of ultrasound irradiation for treatment by a mechanism of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 6.
  • FIG. 8 is a method flow diagram of an ophthalmic treatment method using an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.
  • FIG. 1 is a front view of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention
  • FIG. 2 is an exploded perspective view of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 1
  • FIG. Figure 4 shows a perspective view in a state of being connected to a control operation unit of an ophthalmic ultrasound treatment apparatus using an image scanning method
  • FIG. 4 shows a use state diagram of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG.
  • the ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention includes a base film part 10, a cover film part 20, an ultrasonic element part 30, a power supply part 60, a control operation part ( 50) and the connector portion 40 is included as a configuration constituting the basic structure of the invention.
  • the cover film portion 20 is configured to surround the top surface of the base film portion 10, and may be formed in a circular shape having a predetermined area where all or part of the base film portion 10 overlaps.
  • the cover film portion 20, like the base film portion 10, may be formed in a shape in which the central portion protrudes convexly in a gentle shape compared to the peripheral portion, and wraps in response to the patient's eye (cornea).
  • the ultrasonic element unit 30 is located between the base film unit 10 and the cover film unit 20, and a plurality of piezoelectric elements may be configured to be spaced apart at predetermined intervals. Some of the plurality of piezoelectric elements irradiate ultrasound for treatment in the direction of the patient's eyeball, and others serve to transmit and receive images and signal ultrasound to scan the patient's eye condition.
  • FIG. 5 is a block diagram showing a mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention, respectively.
  • the ultrasonic element unit 30 includes a first element unit 31 and a second element unit 32 each composed of a plurality of piezoelectric elements of different types.
  • it may include an ultrasonic transducer (33, Ultrasonic transducer) for converting the electrical energy received within the ultrasonic frequency range into physical energy, or conversely, converts the received physical energy into electrical energy.
  • Ultrasonic transducer for converting the electrical energy received within the ultrasonic frequency range into physical energy, or conversely, converts the received physical energy into electrical energy.
  • the first element portion 31 and the second element portion 32 are preferably spaced apart from each other in a form having a certain regularity. As shown through the drawings, the first element portion 31 may be disposed in a circular shape in a circular inner region formed by the second element portion 32, as well as a first element separately from the illustrated one A portion 31 may be disposed in an outer region of the second element portion 32.
  • the first element unit 31 is composed of a plurality of piezoelectric elements for irradiating ultrasound for treatment in the patient's eye direction.
  • the first element portion 31 is a therapeutic beam generator 311 (beamformer) for generating ultrasonic beams for eye treatment, a first pulse generator 312 (pulse geneartor) for generating vibrations in the therapeutic ultrasound, and the treatment It has a first ultrasound amplifier (313, Amplifier) for amplifying the ultrasound and a therapeutic ultrasound transmission unit 310 including a match filter (314, Match Filter) to match the input signal of the therapeutic ultrasound.
  • a therapeutic beam generator 311 beamformer
  • a first pulse generator 312 pulse geneartor
  • the treatment It has a first ultrasound amplifier (313, Amplifier) for amplifying the ultrasound and a therapeutic ultrasound transmission unit 310 including a match filter (314, Match Filter) to match the input signal of the therapeutic ultrasound.
  • the therapeutic ultrasound transmission unit 310 transmits a therapeutic ultrasound signal to the ultrasonic converter unit 33. Thereafter, the ultrasonic transducer unit 33 treats the patient's eyeball by converting electrical energy into physical energy within the received ultrasonic frequency range for treatment and providing it to the patient's eyeball.
  • the therapeutic ultrasound may be characterized in that it is a low intensity focused ultrasound (Low Intensity Focused Ultrasound,'LIFU').
  • the low intensity focused ultrasound according to an embodiment of the present invention has a relatively weak intensity through a piezoelectric element arranged in plural. Ultrasound can be focused on the patient's eyeball, where it is needed.
  • the therapeutic ultrasound can be divided into 1000 W/cm 2 or higher intensity therapeutic ultrasound and 10 mW/cm 2 to 50 W/cm 2 low intensity therapeutic ultrasound. Normally, focusing region intensity 3-50 W/cm 2 ) is irradiated to induce vibration of target tissue molecules.
  • the sound field of the ultrasound for treatment irradiated according to the first element unit 31 is the focal region, the intensity of the focal region, the pulse repetition period, the pulse width, the acoustic operating frequency, the irradiation time, the focal length, etc. It is determined by the control element of. At this time, the above-described control elements are adjusted by the control system of the control operation unit 50 of the present invention, and detailed description thereof will be described later.
  • the second element unit 32 is composed of a plurality of piezoelectric elements for transmitting and receiving ultrasound for scanning an ultrasound image of the eye, to calculate the presbyopia position and level of the patient's eye Acquire data.
  • the second element unit 32 includes an image transmitting unit 320 that transmits an ultrasound signal for image scanning of the eyeball, and transistors 340 and T/ that convert ultrasound signals to the eyeball as a reception signal. R switch), an image receiving unit 330 for receiving an ultrasound signal for image scanning from the eyeball.
  • the image transmission unit 320 includes a beamformer 321 that generates transmission ultrasound for image scanning, and a second pulse generator 322 that generates vibrations in the transmission ultrasound for image scanning. ), a transmission low pass filter (323, Low Pass Filter, hereinafter referred to as'LPF') that passes only a frequency signal below a predetermined frequency in the transmission ultrasound for image scanning, and a second amplifier for amplifying the transmission ultrasound for image scanning ( 324).
  • a transmission low pass filter (323, Low Pass Filter, hereinafter referred to as'LPF') that passes only a frequency signal below a predetermined frequency in the transmission ultrasound for image scanning
  • a second amplifier for amplifying the transmission ultrasound for image scanning
  • the image transmission unit 320 provides the above-described transmission ultrasound for image scanning to the ultrasonic converter unit 33.
  • the ultrasonic transducer unit 33 converts electrical energy into physical energy within the received transmission ultrasound range for image scanning, and acquires data for confirming the patient's eye condition. Subsequently, the physical energy is converted into electrical energy again, and receiving ultrasound for image scanning in a corresponding range is provided to the image receiving unit 330.
  • the image receiving unit 330 may include a receiving beamformer 335 for generating ultrasound for image scanning.
  • the low noise amplifier (331, Low Noise Amplifier, hereinafter'LNA') designed to minimize noise in the signal of the receiving ultrasound for image scanning
  • the receiving ultrasound for image scanning Voltage regulated attenuator (332, Voltage Controlled Attenuator, hereinafter referred to as'VGA')
  • programmable gain amplifier 333, Programmable Gain Amplifier, hereinafter referred to as'PGA'
  • a low-pass filter (334, LPF) for passing only the frequency signal of the
  • A/D converter (335, Analog to Digital Converter, hereinafter'ADC') for converting the received ultrasound for image scanning from an analog signal to a digital signal
  • It may include a receiving beamformer 335 for generating ultrasound for image scanning.
  • the low-noise amplifiers 331 and LNA serve to amplify a received weak radio frequency (RF) signal or to a signal of an appropriate level for processing in other receiver circuits.
  • RF radio frequency
  • the gain amplifiers 333 and PGA are programmed to serve to amplify the electrical signal of the received ultrasound for image scanning.
  • the reception low-pass filters 334 and LPF pass only frequency signals below a predetermined frequency among the received ultrasound signals for image scanning, and the A/D converters 335 and ADC scan images below the specified frequency. It is configured to convert the received ultrasonic signal into a digital signal and transmit it.
  • the reception beam former 335 provides an ultrasound beam for image scanning of the digital signal to the control operation unit 50.
  • the control operation unit 50 calculates the presbyopia state or position of the patient's eyeball based on the provided data, and determines a control element for setting the treatment requirements of the first element unit 31 based on the calculation.
  • the ultrasonic element unit 30 may further include a third element unit 34 (not shown) composed of a plurality of piezoelectric elements.
  • the third element portion 34 is spaced apart with a certain regularity, and can irradiate ultrasound in the patient's cornea direction.
  • the third element unit 34 is characterized in that it comprises an infrared (IR) sensor for obtaining the temperature information of the patient's cornea and lens.
  • IR infrared
  • the third element unit 34 provides temperature information of the patient's eyeball measured through the infrared sensor to the control operation unit 50, and the temperature information is utilized as a calculation data element of the control operation unit 50. That is, as will be described later, the control operation unit 50 comprehensively calculates not only the image and various data acquired from the second element unit 32, but also the temperature information acquired from the third element unit 34, so that the patient's The eye state is grasped, and a control element set value of the first element unit 31 for ultrasound treatment is calculated.
  • the power supply unit 60 is configured to supply power to the ultrasonic element unit 30.
  • the ultrasonic element unit 30 may be applied in a separate technical configuration form spaced apart from each other, and may be configured as an integral part by being applied separately in the form of a battery.
  • the control operation unit 50 is configured to control ultrasonic irradiation of the ultrasonic element unit 30 based on a value calculated by receiving data from the ultrasonic element unit 30. More specifically, the data obtained from the second element unit 32 is scanned for an image of the eye condition of the basic patient to calculate the setting of control elements for ultrasound treatment, and accordingly, the first element unit 31 is treated It serves to adjust the control elements to irradiate the ultrasonic waves. A detailed description of the control system through the control operation unit 50 will be described later.
  • the control operation unit 50 may be applied in a separate technical configuration form spaced apart from the ultrasonic element unit 30. Can be configured.
  • the connector portion 40 is configured such that the ultrasonic element portion 30 is electrically connected, and is located on either side of the base film portion 10 or the cover film portion 20. That is, the ultrasonic element unit 30 is electrically connected to the power supply unit 60 so as to receive power, and serves to electrically connect the control operation unit 50 to communicate with it.
  • one side of the connector portion 40 is separated in both directions toward the ultrasonic element portion 30 so that one end 40a has a first element portion 31 and the other end 40b has a second element portion 32 ) And each of them is electrically connected.
  • the opposite side of the connector portion 40 is separately spaced or electrically connected to the power supply unit 60 and the control operation unit 50 formed integrally.
  • FIG. 6 is a block diagram showing the mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method in which signals are independently transmitted to a plurality of devices according to an embodiment of the present invention
  • FIG. 7 is an image scanning method of FIG. 6. It shows a schematic diagram showing the form of ultrasonic irradiation for treatment by the mechanism of the used ultrasonic treatment apparatus.
  • each independent match filter 314 and the corresponding delay line (Delay line, 315) It characterized in that it includes each.
  • the delay line 315 serves to delay the transmission of the output signal from the input signal.
  • the delay line 315 of the present invention is irradiated by allowing the control signals transmitted from the control operation unit 50 to have different arrival times for the match filters 314 of respective elements.
  • the intensity of the direction of the ultrasonic wave can be controlled.
  • the delay degree of a signal from the control operation unit 50 may be adjusted in each delay line 315.
  • the ultrasound treatment apparatus of the present invention can treat the eyeball, lens presbyopia, cataract, etc. by appropriately controlling the horizontal or vertical focal position, depth of focus, etc. for irradiating sound waves for treatment.
  • FIG. 8 illustrates a method flow diagram of an ophthalmic treatment method using an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.
  • a control system for the ultrasonic element unit 30 of the control operation unit 50 of the present invention will be described in detail with reference to FIG. 8, in particular, a control system as a treatment method for presbyopic eye treatment.
  • the ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention is mounted on the eyeball on the cornea of a patient. Thereafter, as a first step, the control operation unit 50 transmits a control signal corresponding to the ultrasound scanning step S10 for checking the presbyopia state of the eyeball to the second element unit 32.
  • the second element unit 32 provides transmission ultrasound for image scanning through the image transmission unit 320, and then receives ultrasound for image scanning through the ultrasonic converter unit 33, the image receiving unit 330. Is received through.
  • the second element unit 32 provides the image scanning data acquired as above to the control operation unit 50.
  • the control operation unit 50 calculates an image based on the image scanning data, and scans the patient's eye condition. Thereafter, the control operation unit 50 undergoes a lens presbyopia analysis step (S20) for confirming the position and level of presbyopia for the patient's lens.
  • the control operation unit 50 derives a control signal for transmission to the first element unit 31. More specifically, based on the presbyopia of the acquired lens, any one of the control elements such as the focal region of the therapeutic ultrasound, the intensity of the focal region, pulse repetition period, pulse width, acoustic operating frequency, irradiation time, and focal length.
  • the ultrasonic treatment condition setting step (S30) for setting abnormalities is reached.
  • control operation unit 50 independently adjusts the arrival times of the control signals for the plurality of elements with respect to the first element portion 31, respectively, a horizontal or vertical focus position and depth of focus for irradiating sound waves for treatment.
  • the back can be appropriately controlled.
  • control operation unit 50 transmits the set control signal to the first element unit 31, and the first element unit 31 irradiates ultrasound for treatment according to the treatment requirements set by the above control signal. Accordingly, an ultrasound treatment step (S40) is performed in which the ultrasound transducer unit 33 provides energy at a required position of the patient's lens to perform presbyopia treatment.
  • the control operation unit 50 transmits a control signal corresponding to the ultrasound scanning step (S50) in order to examine the effect of treatment of lens presbyopia on the second element unit 32. For this reason, the second element unit 32 receives the image scanning image and various data as in the method of the lens presbyopia analysis step S20 described above, and provides it to the control operation unit 50.
  • the control operation unit 50 performs a result analysis step (S60) of determining the effect of treating the presbyopia of the patient's eye, based on the image and data by scanning the image above, and determining whether additional ultrasound treatment is necessary. As a result, when it is determined that additional treatment is necessary, the control operation unit 50 repeatedly executes the control system from the above-described treatment condition setting step (S30) to the result analysis step (S60).
  • the ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention acquires images and various data on the presbyopia position and level of a patient's lens, and sets ultrasound treatment conditions accordingly. It enables precise and efficient ultrasound treatment according to the eye environment, presbyopia of the lens, and cataracts.
  • the system checks the effectiveness of the ultrasound treatment and checks for re-treatment. The completeness of the treatment can be ensured.

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Abstract

One embodiment of the present invention provides an ophthalmic ultrasonic treatment device using an image scanning method, comprising: a base film part; a cover film part partially or entirely overlapping with the base film part; an ultrasonic element part composed of a plurality of elements spaced apart at a predetermined distance between the base film part and the cover film part, and transmitting and receiving ultrasonic waves to and from an eyeball; a power supply part for supplying power to the ultrasonic element part; a control operation part for controlling the ultrasonic element part; and a connector part for electrically connecting the ultrasonic element part to the control operation part and the power supply part.

Description

이미지 스캔 방식을 이용한 안과용 초음파 치료기기Ophthalmic ultrasound therapy device using image scanning method

본 발명은 안과용 초음파 치료기기에 관한 것으로, 더욱 상세하게는 초기 초음파 검사를 통해 안구 상태를 스캐닝하고, 취득한 이미지 데이터를 근거로 안구 치료를 위한 초음파를 조사하도록 제어하는 안과용 초음파 치료기기에 관한 것이다.The present invention relates to an ultrasound treatment apparatus for ophthalmology, and more particularly, to an ultrasound treatment apparatus for ophthalmology that scans the eye condition through initial ultrasound examination and controls to irradiate ultrasound for eye treatment based on the acquired image data. will be.

빠른 속도의 인구고령화가 진행되고 있는 가운데 노화로 인한 질병 역시 증가하고 있다. 특히, 신체의 가장 민감한 부위 중 하나인 안구는 노안으로 인해 백내장 등의 질환을 유발하는 경우가 많아 문제된다. Aging populations are increasing as the population is rapidly aging. In particular, one of the most sensitive parts of the body, the eyeball is a problem because it often causes diseases such as cataracts due to presbyopia.

노안은 신체의 노화로 인하여 수정체의 기능이 저하되어, 근거리 초점을 맞추지 못하는 상태를 말한다. 보통 40세 이후부터 발생하게 되는데, 현대에는 휴대폰과 PC 사용 등의 잦은 근거리 작업으로 인하여 30대 전후에 발생하는 경우도 점차적으로 증가하고 있는 추세이다.Presbyopia refers to a condition in which the function of the lens decreases due to aging of the body, and thus it is unable to focus at close range. It usually occurs after the age of 40, but in modern times, the number of cases occurring around the 30s is gradually increasing due to frequent short-term work such as the use of mobile phones and PCs.

이러한 노안 증상이 발생되기 시작하면 돋보기 안경을 통해서 불편함을 개선시킬 수 있으나, 최근에는 의료기술이 발달된 만큼 돋보기 안경에 의존하지 않고 안구의 기능을 향상시키기 위한 다양한 치료방법의 연구가 활발하게 진행되고 있다.When these presbyopia symptoms begin to occur, discomfort may be improved through magnifying glasses, but recently, as medical technology has been developed, research on various treatment methods to improve the function of the eye does not depend on magnifying glasses. Is becoming.

그 중에서도 최근에는 초음파를 이용한 다양한 치료방법이 각광받고 있다. 초음파는 사람의 청력 범위(16Hz∼20kHz) 이상의 주파수를 가지는 음향적압력파(acoustic pressure wave)로서, 생체 조직을 통하여 전달되는 기계적 에너지의 한 형태이다. 현재 치료 초음파는 역학적 효과, 공명 효과, 열적 효과의 세가지 물리적인 효과를 이용하여 치료의 대상, 목적 및 특성에 맞추어 적합한 용도에 따라 다양한 사용되고 있다.Among them, various treatment methods using ultrasound have recently been spotlighted. Ultrasound is an acoustic pressure wave having a frequency above a human hearing range (16 Hz to 20 kHz), and is a form of mechanical energy transmitted through biological tissue. Currently, therapeutic ultrasound is used in various ways according to the purpose, purpose, and characteristics of treatment using three physical effects: mechanical effect, resonance effect, and thermal effect.

초음파를 이용한 치료기기 또는 방법은 이는 외과적 시술 없이 비침습적으로 시술할 수 있을 뿐만 아니라 시술 회복 시간이 빠르다는 장점이 있어, 국내뿐만 아니라 전세계적으로 활발히 보급되고 있는 추세이다. The treatment device or method using ultrasound has the advantage that it can be performed non-invasively without surgical procedures and has a fast recovery time, so it is actively spread not only in Korea but also worldwide.

다만 인간의 안구는 그 구조 또는 형상은 각 개인마다 조금씩 차이가 있으며, 치료 초음파를 조사하여 노안이 문제되는 수정체를 치료하고자 하는 경우에는 정밀도 및 기술력이 더욱 크게 요구된다. 현재 의료시장에는 다양한 안과용 초음파 치료방법에 대한 기술이 개시되고 있으나, 기존의 기술에 의하더라도 각각의 수정체에 대한 정확한 데이터를 기반으로 한 치료기기 등의 제시가 미비한 상황이다.However, the structure or shape of the human eye is slightly different for each individual, and in order to treat a lens in which presbyopia is a problem by irradiating therapeutic ultrasound, greater precision and technology are required. Currently, various medical ophthalmic ultrasound treatment techniques have been disclosed in the medical market, but even the existing technique has been insufficient in presenting treatment devices based on accurate data for each lens.

선행기술문헌Prior art literature

대한민국 등록특허공보 제10-0991846호(2010.10.28.)Republic of Korea Registered Patent Publication No. 10-0991846 (2010.10.28.)

본 발명은 전술한 종래 기술의 문제점을 해결하기 위한 것으로, 본 발명의 목적은 이미지 스캔 방식으로 환자의 안구 상태에 대한 데이터를 취득하여 이를 바탕으로 초음파 치료조건 및/또는 재치료여부를 제어하는 안과용 초음파 치료기기를 제공하는 것이다.The present invention is to solve the problems of the above-described prior art, the object of the present invention is to obtain data on the patient's eye state by image scanning method based on it to control the ultrasound treatment conditions and / or re-treatment for ophthalmology It is to provide an ultrasonic treatment device.

본 발명의 일 측면은 베이스필름부; 상기 베이스필름부와 전부 또는 일부가 중첩되는 커버필름부; 상기 베이스필름부와 상기 커버필름부의 사이에 소정의 거리를 두고 이격된 복수 개의 소자로 형성되며, 안구방향으로 초음파를 송수신하는 초음파소자부; 상기 초음파소자부에 전력을 공급하는 전원공급부; 상기 초음파소자부를 제어하는 제어연산부; 및 상기 초음파소자부를 상기 제어연산부 및 상기 전원공급부를 전기적으로 연결시키는 커넥터부를 포함하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기을 제공한다.One aspect of the present invention is a base film portion; A cover film part overlapping all or part of the base film part; An ultrasonic element portion formed of a plurality of elements spaced apart at a predetermined distance between the base film portion and the cover film portion, and transmitting/receiving ultrasonic waves in the eyeball direction; A power supply unit supplying power to the ultrasonic element unit; A control operation unit for controlling the ultrasonic element unit; And a connector part electrically connecting the ultrasonic element part to the control operation part and the power supply part.

일 실시예에 있어서, 상기 초음파소자부는 치료용 초음파를 조사하는 제1소자부와; 이미지 스캐닝용 초음파를 송수신하는 제2소자부; 및 초음파 주파수 범위 내에서 전기적 에너지를 물리적 에너지로 변환하거나 또는 물리적 에너지를 전기적 에너지로 변환하 초음파변환기부를 더 포함하며, 상기 제어연산부는 상기 제2소자부로부터의 스캔 정보를 전달받아 상기 제1소자가 치료용 초음파를 조사하는 제어요소를 설정하는 것일 수 있다.In one embodiment, the ultrasonic element portion includes a first element portion for irradiating ultrasound for treatment; A second element unit for transmitting and receiving ultrasound for image scanning; And an ultrasonic converter for converting electrical energy into physical energy or converting physical energy into electrical energy within an ultrasonic frequency range, wherein the control operation unit receives the scan information from the second device unit and receives the first device. It may be to set a control element for irradiating ultrasound for treatment.

일 실시예에 있어서, 상기 제2소자부는, 안구에 대하여 이미지 스캔을 위한 초음파 신호를 전송하는 영상전송부; 안구에 초음파의 전송신호를 수신신호로 전환하는 트랜지스터; 및 안구로부터 이미지 스캔을 위한 초음파 신호를 수신하는 영상수신부를 더 포함하는 것일 수 있다.In one embodiment, the second element unit, an image transmission unit for transmitting an ultrasound signal for image scanning for the eyeball; Transistor for converting the transmission signal of the ultrasound to the eye to the received signal; And an image receiving unit receiving an ultrasound signal for image scanning from the eyeball.

일 실시예에 있어서, 상기 영상전송부는, 이미지 스캔을 위한 전송 초음파 빔을 발생시키는 전송빔형성기; 상기 이미지 스캔용 전송 초음파에 진동을 발생시키는 제2펄스발생기; 상기 이미지 스캔용 전송 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 전송저역통과필터; 및 상기 이미지 스캔용 전송 초음파를 증복시키는 제2증폭기를 더 포함하는 것일 수 있다.In one embodiment, the image transmission unit, a transmission beam former for generating a transmission ultrasound beam for image scanning; A second pulse generator that generates vibrations in the transmission ultrasound for image scanning; A transmission low pass filter for passing only frequency signals below a predetermined frequency in the transmission ultrasound for image scanning; And a second amplifier that amplifies the transmission ultrasound for image scanning.

일 실시예에 있어서, 상기 영상수신부는, 이미지 스캔용 수신 초음파의 신호에서 잡음이 최소화되도록 설계된 저잡음 증폭기; 상기 이미지 스캔용 수신 초음파 신호의 전압을 조정하는 전압조정 감쇄기; 상기 이미지 스캔용 수신 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 수신저역통과필터; 상기 이미지 스캔용 수신 초음파를 아날로그 신호에서 디지털 신호로 전환하는 A/D 컨버터; 및 이미지 스캔을 위한 초음파 빔을 발생시켜, 상기 제어연산부에 제공하는 수신빔형성기를 더 포함하는 것일 수 있다.In one embodiment, the image receiving unit, a low-noise amplifier designed to minimize noise in the signal of the received ultrasound for image scanning; A voltage adjustment attenuator for adjusting the voltage of the received ultrasound signal for image scanning; A reception low pass filter for passing only frequency signals below a predetermined frequency in the reception ultrasound for image scanning; An A/D converter that converts the received ultrasound for image scanning from an analog signal to a digital signal; And a reception beam former that generates an ultrasound beam for image scanning and provides the control beam to the control operation unit.

일 실시예에 있어서, 상기 제1소자부는, 안구 치료용 초음파 빔을 생성하는 치료 초음파의 치료빔형성기; 상기 치료용 초음파에 진동을 발생시키는 제1펄스발생기; 상기 치료용 초음파를 증폭시키는 제1증폭기; 및 입력된 상기 치료용 초음파의 신호를 정합시키는 매치필터를 포함하는 치료초음파 전송부가 구비되며, 상기 치료용 초음파는 저강도 집속형 초음파인 것일 수 있다.In one embodiment, the first device unit, a therapeutic beam forming machine of therapeutic ultrasound to generate an ultrasound beam for eye treatment; A first pulse generator that generates vibrations in the therapeutic ultrasound; A first amplifier to amplify the therapeutic ultrasound; And it is provided with a therapeutic ultrasound transmission unit including a match filter to match the input signal of the therapeutic ultrasound, the therapeutic ultrasound may be a low intensity focused ultrasound.

일 실시예에 있어서, 상기 제어연산부는, 상기 제2소자부로부터 전달받은 스캔 정보로 안구의 수정체 노안 위치 및 정도를 연산하여, 상기 제 1소자부가 조사하는 치료용 초음파의 초점영역, 초점영역의 강도, 펄스 반복주기, 펄스 폭, 음향 작동 주파수, 조사시간, 초점거리 중 어느 하나 이상을 제어하되, 상기 제1소자부에 대하여 복수 개의 소자에 대한 제어신호의 도달시기를 각각 독립적으로 조절하는 것일 수 있다.In one embodiment, the control operation unit calculates the presbyopia position and degree of lens presbyopia of the eye using the scan information received from the second device unit, and the focus area and focus area of the ultrasound for treatment by the first device unit are irradiated. Controlling any one or more of intensity, pulse repetition period, pulse width, acoustic operating frequency, irradiation time, and focal length, but independently adjusting the arrival times of control signals for a plurality of elements with respect to the first element part Can be.

본 발명의 일 측면에 따르면, 환자의 수정체의 노안 위치 및 수준 등에 대한 영상 및 다양한 데이터를 취득하여 이에 따른 초음파 치료조건을 설정하게 되므로, 다양한 환자의 안구 환경에 따른 정밀하고 효율적인 초음파 치료를 가능케 수 있다.According to one aspect of the present invention, by obtaining images and various data on the presbyopia position and level of the patient's lens, and setting ultrasound treatment conditions accordingly, it is possible to enable precise and efficient ultrasound treatment according to the ocular environment of various patients. have.

더불어, 전술한 초음파 치료 이후 다시금 환자의 수정체의 노안 위치 및 수준 등에 대한 영상 및 다양한 데이터를 취득하여, 해당 초음파 치료의 효과를 확인하고 재치료 여부를 점검하는 시스템을 통하여, 인체의 특히 민감한 부위의 안구 치료에 대한 완전성을 확보할 수 있다.In addition, after the above-described ultrasound treatment, the image and various data on the presbyopia position and level of the patient's lens are acquired again, and the system checks the effect of the ultrasound treatment and checks for re-treatment, thereby observing the eyeballs of particularly sensitive areas of the human body. The completeness of the treatment can be ensured.

본 발명의 효과는 상기한 효과로 한정되는 것은 아니며, 본 발명의 상세한 설명 또는 청구범위에 기재된 발명의 구성으로부터 추론 가능한 모든 효과를 포함하는 것으로 이해되어야 한다.It should be understood that the effects of the present invention are not limited to the above-described effects, and include all effects that can be deduced from the configuration of the invention described in the detailed description or claims of the invention.

도 1은 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 정면도이다.1 is a front view of an ophthalmic ultrasound therapy apparatus using an image scanning method according to an embodiment of the present invention.

도 2는 도 1의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 분해 사시도이다.FIG. 2 is an exploded perspective view of the ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 1.

도 3은 도 2의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 제어연산부 등과의 연결된 상태에서의 사시도이다.FIG. 3 is a perspective view of the ophthalmic ultrasound therapy apparatus using the image scanning method of FIG. 2 in a connected state with a control operation unit.

도 4는 도 3의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 사용상태도이다.4 is a state diagram of the use of the ophthalmic ultrasound therapy apparatus using the image scanning method of FIG. 3.

도 5는 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘을 나타내는 블록도이다.5 is a block diagram showing the mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.

도 6은 본 발명의 일 실시예에 의하여 복수 개의 소자에 대하여 독립적으로 신호가 전달되는 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘을 나타내는 블록도이다.6 is a block diagram showing a mechanism of an ophthalmic ultrasound therapy apparatus using an image scanning method in which signals are independently transmitted to a plurality of devices according to an embodiment of the present invention.

도 7은 도 6의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘에 의한 치료용 초음파 조사형태를 도시한 모식도이다.FIG. 7 is a schematic diagram showing a form of ultrasound irradiation for treatment by a mechanism of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 6.

도 8은 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기을 이용한 안과용 치료방법의 방법흐름도이다.8 is a method flow diagram of an ophthalmic treatment method using an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.

이하에서는 첨부한 도면을 참조하여 본 발명을 설명하기로 한다. 그러나 본 발명은 여러 가지 상이한 형태로 구현될 수 있으며, 따라서 여기에서 설명하는 실시예로 한정되는 것은 아니다. 그리고 도면에서 본 발명을 명확하게 설명하기 위해서 설명과 관계없는 부분은 생략하였으며, 명세서 전체를 통하여 유사한 부분에 대해서는 유사한 도면 부호를 붙였다.Hereinafter, the present invention will be described with reference to the accompanying drawings. However, the present invention may be implemented in various different forms, and thus is not limited to the embodiments described herein. In addition, in order to clearly describe the present invention in the drawings, parts irrelevant to the description are omitted, and like reference numerals are assigned to similar parts throughout the specification.

명세서 전체에서, 어떤 부분이 다른 부분과 "연결"되어 있다고 할 때, 이는 "직접적으로 연결"되어 있는 경우뿐 아니라, 그 중간에 다른 부재를 사이에 두고 "간접적으로 연결"되어 있는 경우도 포함한다. 또한 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 구비할 수 있다는 것을 의미한다.Throughout the specification, when a part is "connected" to another part, this includes not only "directly connected" but also "indirectly connected" with another member in between. . Also, when a part “includes” a certain component, this means that other components may be further provided instead of excluding other components, unless otherwise stated.

이하, 첨부된 도면을 참고하여 본 발명의 실시예를 상세히 설명하기로 한다.Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

도 1은 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 정면도를, 도 2는 도 1의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 분해 사시도를, 도 은는 도 2의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 제어연산부 등과의 연결된 상태에서의 사시도를, 도 4는 도 3의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 사용상태도를 각각 도시한다.1 is a front view of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention, FIG. 2 is an exploded perspective view of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG. 1, and FIG. Figure 4 shows a perspective view in a state of being connected to a control operation unit of an ophthalmic ultrasound treatment apparatus using an image scanning method, and FIG. 4 shows a use state diagram of an ophthalmic ultrasound treatment apparatus using the image scanning method of FIG.

도시된 바와 같이, 본 발명에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기는 베이스필름부(10), 커버필름부(20), 초음파소자부(30), 전원공급부(60), 제어연산부(50) 및 커넥터부(40)를 발명의 기본 구조를 이루는 구성으로 포함한다.As shown, the ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention includes a base film part 10, a cover film part 20, an ultrasonic element part 30, a power supply part 60, a control operation part ( 50) and the connector portion 40 is included as a configuration constituting the basic structure of the invention.

베이스필름부(10)와 환자의 안구의 각막에 접촉할 수 있는 구성으로, 소정의 면적을 갖는 원형 형태로 형성될 수 있다. 보다 구체적으로는 중심부분이 주변부분에 비하여 완만한 형태로 볼록 돌출되어, 환자의 안구(각막)에 대응되어 감싸는 형태로 형성될 수 있다.It is a configuration that can contact the base film portion 10 and the cornea of the patient's eye, and may be formed in a circular shape having a predetermined area. More specifically, the central portion protrudes convexly in a gentle shape compared to the peripheral portion, and may be formed in a shape that wraps around the patient's eye (cornea).

커버필름부(20)는 베이스필름부(10)의 상면을 감싸는 구성으로, 상기 베이스필름부(10)와 전부 또는 일부가 중첩되는 소정의 면적을 갖는 원형 형태로 형성될 수 있다. 상기 커버필름부(20)도 베이스필름부(10)와 마찬가지로 중심부분이 주변부분에 비하여 완만한 형태로 볼록 돌출되어, 환자의 안구(각막)에 대응되어 감싸는 형태로 형성될 수 있다.The cover film portion 20 is configured to surround the top surface of the base film portion 10, and may be formed in a circular shape having a predetermined area where all or part of the base film portion 10 overlaps. The cover film portion 20, like the base film portion 10, may be formed in a shape in which the central portion protrudes convexly in a gentle shape compared to the peripheral portion, and wraps in response to the patient's eye (cornea).

초음파소자부(30)는 베이스필름부(10)와 커버필름부(20)의 사이에 위치하며, 복수 개의 압전소자가 소정의 간격을 두고 이격 배치되도록 구성될 수 있다. 상기 복수 개의 압전소자 중 일부는 환자의 안구 방향으로 치료를 위한 초음파를 조사하며, 다른 일부는 환자의 안구 상태를 스캐닝하기 영상 및 신호 초음파를 전송 및 수신하는 역할을 한다.The ultrasonic element unit 30 is located between the base film unit 10 and the cover film unit 20, and a plurality of piezoelectric elements may be configured to be spaced apart at predetermined intervals. Some of the plurality of piezoelectric elements irradiate ultrasound for treatment in the direction of the patient's eyeball, and others serve to transmit and receive images and signal ultrasound to scan the patient's eye condition.

도 5는 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘을 나타내는 블록도를 각각 도시한다. 5 is a block diagram showing a mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention, respectively.

이하, 도 5를 참조하여 본 발명의 일 실시예에 따른 초음파소자부(30)의 메커니즘을 상세히 설명한다.Hereinafter, the mechanism of the ultrasonic element unit 30 according to an embodiment of the present invention will be described in detail with reference to FIG. 5.

본 발명의 일 실시예에 따른 초음파소자부(30)는 서로 다른 종류의 복수 개의 압전소자로 각각 구성되는 제1소자부(31) 및 제2소자부(32)를 포함한다. 또한, 초음파 주파수 범위 내에서 수신한 전기적 에너지를 물리적 에너지로 변환하거나, 반대로 수신한 물리적 에너지를 전기적 에너지로 변환하는 초음파변환기부(33, Ultrasonic transducer)를 포함할 수 있다. The ultrasonic element unit 30 according to an embodiment of the present invention includes a first element unit 31 and a second element unit 32 each composed of a plurality of piezoelectric elements of different types. In addition, it may include an ultrasonic transducer (33, Ultrasonic transducer) for converting the electrical energy received within the ultrasonic frequency range into physical energy, or conversely, converts the received physical energy into electrical energy.

제1소자부(31)와 제2소자부(32)는 일정한 규칙성을 갖는 형태로 각각 이격 배치됨이 바람직하다. 도면을 통해 도시된 바와 같이, 상기 제1소자부(31)가 상기 제2소자부(32)가 이루는 원형의 내측 영역에 원형으로 배치될 수 있음은 물론, 도시된 바와는 별개로 제1소자부(31)가 상기 제2소자부(32)의 외측 영역에 배치될 수 있다.The first element portion 31 and the second element portion 32 are preferably spaced apart from each other in a form having a certain regularity. As shown through the drawings, the first element portion 31 may be disposed in a circular shape in a circular inner region formed by the second element portion 32, as well as a first element separately from the illustrated one A portion 31 may be disposed in an outer region of the second element portion 32.

이하에서는 설명의 편의상, 도시된 바와 같이 제1소자부(31)가 원형으로 배치된 제2소자부(32)의 내측 영역에 원형으로 배치된 경우를 기준으로 설명한다.Hereinafter, for convenience of description, a description will be given based on a case in which the first element portion 31 is circularly disposed in the inner region of the second element portion 32 which is circularly disposed.

본 발명의 일 실시예에 따른 제1소자부(31)는 환자의 안구 방향으로 치료를 위한 초음파를 조사하기 위한 복수 개의 압전소자로 구성된다. The first element unit 31 according to an embodiment of the present invention is composed of a plurality of piezoelectric elements for irradiating ultrasound for treatment in the patient's eye direction.

제1소자부(31)는 안구 치료용 초음파 빔을 생성하는 치료 초음파의 치료빔형성기(311, Beamformer), 상기 치료용 초음파에 진동을 발생시키는 제1펄스발생기(312, Pulse Geneartor), 상기 치료용 초음파를 증폭시키는 제1증폭기(313, Amplifier) 및 입력된 상기 치료용 초음파의 신호를 정합시키는 매치필터(314, Match Filter)를 포함하는 치료초음파 전송부(310)를 구비한다. The first element portion 31 is a therapeutic beam generator 311 (beamformer) for generating ultrasonic beams for eye treatment, a first pulse generator 312 (pulse geneartor) for generating vibrations in the therapeutic ultrasound, and the treatment It has a first ultrasound amplifier (313, Amplifier) for amplifying the ultrasound and a therapeutic ultrasound transmission unit 310 including a match filter (314, Match Filter) to match the input signal of the therapeutic ultrasound.

치료초음파 전송부(310)는 치료용 초음파 신호를 초음파변환기부(33)에 전송하게 한다. 이후, 상기 초음파변환기부(33)는 수신한 상기 치료용 초음파 주파수 범위 내에서 전기적 에너지를 물리적 에너지로 변환하여 환자의 안구에 제공하는 방식으로 환자의 안구를 치료한다.The therapeutic ultrasound transmission unit 310 transmits a therapeutic ultrasound signal to the ultrasonic converter unit 33. Thereafter, the ultrasonic transducer unit 33 treats the patient's eyeball by converting electrical energy into physical energy within the received ultrasonic frequency range for treatment and providing it to the patient's eyeball.

이때, 상기 치료용 초음파는 저강도 집속형 초음파(Low Intensity Focused Ultrasound, 이하 'LIFU')인 것을 특징으로 할 수 있다. 강한 강도의 초음파를 광범위하게 조사하는 기존의 단일소자모듈의 치료용 초음파 조사와 달리, 본 발명의 일 실시예에 따른 상기 저강도 집속형 초음파는 복수 개로 배열된 압전소자를 통하여 상대적으로 약한 강도의 초음파를 환자의 안구에서 필요한 부위에 집중적으로 조사할 수 있다.At this time, the therapeutic ultrasound may be characterized in that it is a low intensity focused ultrasound (Low Intensity Focused Ultrasound,'LIFU'). Unlike the conventional ultrasound treatment for a single device module that irradiates a wide range of ultrasound of a strong intensity, the low intensity focused ultrasound according to an embodiment of the present invention has a relatively weak intensity through a piezoelectric element arranged in plural. Ultrasound can be focused on the patient's eyeball, where it is needed.

치료용 초음파는 1000 W/cm 2 이상의 고강도 치료용 초음파와 10 mW/cm 2∼ 50 W/cm 2 범위의 저강도 치료용 초음파로 나눌 수 있는데, 통상 저강도 집속형 초음파 기기는 집속형 초음파(통상 집속 영역 강도 3∼50 W/cm 2)를 조사하여 타겟 조직 분자의 진동을 유도한다.The therapeutic ultrasound can be divided into 1000 W/cm 2 or higher intensity therapeutic ultrasound and 10 mW/cm 2 to 50 W/cm 2 low intensity therapeutic ultrasound. Normally, focusing region intensity 3-50 W/cm 2 ) is irradiated to induce vibration of target tissue molecules.

본 발명의 일 실시예에 따라 제1소자부(31)에 따라 조사되는 치료용 초음파의 음장은 초점영역, 초점영역의 강도, 펄스 반복주기, 펄스 폭, 음향 작동 주파수, 조사시간, 초점거리 등의 제어요소에 의하여 결정된다. 이때, 전술한 제어요소들은 본 발명의 제어연산부(50)의 제어 시스템에 의하여 조절되며, 이에 대한 자세한 설명은 후술한다.According to an embodiment of the present invention, the sound field of the ultrasound for treatment irradiated according to the first element unit 31 is the focal region, the intensity of the focal region, the pulse repetition period, the pulse width, the acoustic operating frequency, the irradiation time, the focal length, etc. It is determined by the control element of. At this time, the above-described control elements are adjusted by the control system of the control operation unit 50 of the present invention, and detailed description thereof will be described later.

본 발명의 일 실시예에 따른 제2소자부(32)는 안구에 대한 초음파 이미지 스캔을 위한 초음파를 송수신하기 위한 복수 개의 압전소자로 구성되어, 환자의 안구에 대한 노안 위치 및 수준 등을 연산할 수 있는 데이터를 획득한다.The second element unit 32 according to an embodiment of the present invention is composed of a plurality of piezoelectric elements for transmitting and receiving ultrasound for scanning an ultrasound image of the eye, to calculate the presbyopia position and level of the patient's eye Acquire data.

보다 구체적으로는 상기 제2소자부(32)는, 안구에 대하여 이미지 스캔을 위한 초음파 신호를 전송하는 영상전송부(320), 안구에 초음파의 전송신호를 수신신호로 전환하는 트랜지스터(340, T/R switch), 안구로부터 이미지 스캔을 위한 초음파 신호를 수신하는 영상수신부(330)를 포함할 수 있다.More specifically, the second element unit 32 includes an image transmitting unit 320 that transmits an ultrasound signal for image scanning of the eyeball, and transistors 340 and T/ that convert ultrasound signals to the eyeball as a reception signal. R switch), an image receiving unit 330 for receiving an ultrasound signal for image scanning from the eyeball.

본 발명의 일 실시예에 따른 영상전송부(320)는, 이미지 스캔을 위한 전송 초음파를 발생시키는 전송빔형성기(321, Beamformer), 상기 이미지 스캔용 전송 초음파에 진동을 발생시키는 제2펄스발생기(322), 상기 이미지 스캔용 전송 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 전송저역통과필터(323, Low Pass Filter, 이하 'LPF') 및 상기 이미지 스캔용 전송 초음파를 증폭시키는 제2증폭기(324)를 포함할 수 있다.The image transmission unit 320 according to an embodiment of the present invention includes a beamformer 321 that generates transmission ultrasound for image scanning, and a second pulse generator 322 that generates vibrations in the transmission ultrasound for image scanning. ), a transmission low pass filter (323, Low Pass Filter, hereinafter referred to as'LPF') that passes only a frequency signal below a predetermined frequency in the transmission ultrasound for image scanning, and a second amplifier for amplifying the transmission ultrasound for image scanning ( 324).

영상전송부(320)는 상술한 이미지 스캔용 전송 초음파를 초음파변환기부(33)에 제공한다. 상기 초음파변환기부(33)는 수신한 상기 이미지 스캔용 전송 초음파 범위 내에서 전기적 에너지를 물리적 에너지로 변환하여, 이를 환자의 안구 상태를 확인하기 위한 데이터를 획득한다. 이후, 다시금 물리적 에너지를 전기적 에너지로 변환하여 해당 범위 내의 이미지 스캔용 수신 초음파를 영상수신부(330)에 제공한다.The image transmission unit 320 provides the above-described transmission ultrasound for image scanning to the ultrasonic converter unit 33. The ultrasonic transducer unit 33 converts electrical energy into physical energy within the received transmission ultrasound range for image scanning, and acquires data for confirming the patient's eye condition. Subsequently, the physical energy is converted into electrical energy again, and receiving ultrasound for image scanning in a corresponding range is provided to the image receiving unit 330.

본 발명의 일 실시예에 따른 영상수신부(330)는, 이미지 스캔용 수신 초음파의 신호에서 잡음이 최소화되도록 설계된 저잡음증폭기(331, Low Noise Amplifier, 이하 'LNA'), 상기 이미지 스캔용 수신 초음파의 전압을 조정하는 전압조정감쇄기(332, Voltage Controlled Attenuator, 이하 'VGA'), 프로그램이 가능한 이득증폭기(333, Programmable Gain Amplifier, 이하 'PGA'), 상기 이미지 스캔용 수신 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 수신저역통과필터(334, LPF), 상기 이미지 스캔용 수신 초음파를 아날로그 신호에서 디지털 신호로 전환하는 A/D 컨버터(335, Analog to Digital Converter, 이하 'ADC'), 및 이미지 스캔을 위한 초음파를 발생시키는 수신빔형성기(335)를 포함할 수 있다.The image receiving unit 330 according to an embodiment of the present invention, the low noise amplifier (331, Low Noise Amplifier, hereinafter'LNA') designed to minimize noise in the signal of the receiving ultrasound for image scanning, the receiving ultrasound for image scanning Voltage regulated attenuator (332, Voltage Controlled Attenuator, hereinafter referred to as'VGA'), programmable gain amplifier (333, Programmable Gain Amplifier, hereinafter referred to as'PGA'), which is below a specific frequency preset in the received ultrasound for image scanning A low-pass filter (334, LPF) for passing only the frequency signal of the, A/D converter (335, Analog to Digital Converter, hereinafter'ADC') for converting the received ultrasound for image scanning from an analog signal to a digital signal, and It may include a receiving beamformer 335 for generating ultrasound for image scanning.

저잡음증폭기(331, LNA)는 수신된 미약한 무선주파수대(RF) 신호를 다운시키기나 그 밖의 수신기 회로에서 처리하기 위해 적당한 레벨의 신호로 증폭시키는 역할을 한다.The low-noise amplifiers 331 and LNA serve to amplify a received weak radio frequency (RF) signal or to a signal of an appropriate level for processing in other receiver circuits.

전압조정감쇄기(332, VGA)가 이미지 스캔용 수신 초음파 신호의 진폭을 조절하여 전압을 조정하면, 이득증폭기(333, PGA)가 상기 이미지 스캔용 수신 초음파의 전기적 신호를 증폭시키는 역할을 하도록 프로그래밍된다.When the voltage adjusting attenuators 332 and VGA adjust the voltage by adjusting the amplitude of the received ultrasound signal for image scanning, the gain amplifiers 333 and PGA are programmed to serve to amplify the electrical signal of the received ultrasound for image scanning. .

이후, 수신저역통과필터(334, LPF)는 이미지 스캔용 수신 초음파 신호 중 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키게 되고, A/D 컨버터(335, ADC)가 상기 특정 주파수 이하의 이미지 스캔용 수신 초음파 신호를 디지털 신호로 전환하여 전달하도록 구성된다. Subsequently, the reception low-pass filters 334 and LPF pass only frequency signals below a predetermined frequency among the received ultrasound signals for image scanning, and the A/D converters 335 and ADC scan images below the specified frequency. It is configured to convert the received ultrasonic signal into a digital signal and transmit it.

수신빔형성기(335)가 상기 디지털 신호에 대하여 이미지 스캔을 위한 초음파 빔을 제어연산부(50)에 제공하게 된다. 상기 제어연산부(50)는 제공된 데이터를 바탕으로 환자 안구의 노안 상태 또는 위치 등에 대한 연산을 하고, 이를 기초로 제1소자부(31)의 치료요건을 설정하는 제어요소를 결정한다.The reception beam former 335 provides an ultrasound beam for image scanning of the digital signal to the control operation unit 50. The control operation unit 50 calculates the presbyopia state or position of the patient's eyeball based on the provided data, and determines a control element for setting the treatment requirements of the first element unit 31 based on the calculation.

한편, 본 발명의 또 다른 실시예에 따른 초음파소자부(30)는 복수 개의 압전소자로 구성되는 제3소자부(34, 미도시)를 더 포함할 수 있다. 상기 제3소자부(34)는 제1,2소자부(31,32)와 마찬가지로 일정한 규칙성을 갖고 이격배치 되며, 환자의 각막 방향으로 초음파를 조사할 수 있다. 이때, 상기 제3소자부(34)는 환자의 각막 및 수정체의 온도정보를 획득하는 적외선(IR) 센서를 구비하는 것을 특징으로 한다.Meanwhile, the ultrasonic element unit 30 according to another embodiment of the present invention may further include a third element unit 34 (not shown) composed of a plurality of piezoelectric elements. Like the first and second element portions 31 and 32, the third element portion 34 is spaced apart with a certain regularity, and can irradiate ultrasound in the patient's cornea direction. At this time, the third element unit 34 is characterized in that it comprises an infrared (IR) sensor for obtaining the temperature information of the patient's cornea and lens.

제3소자부(34)는 적외선 센서를 통해 측정된 환자 안구의 온도 정보를 제어연산부(50)에 제공하고, 상기 온도 정보는 상기 제어연산부(50)의 연산 데이터요소로 활용된다. 즉, 후술하는 바와 같이 상기 제어연산부(50)는 제2소자부(32)로부터 취득하는 영상 및 다양한 데이터뿐만 아니라, 상기 제3소자부(34)로부터 취득하는 온도 정보를 종합적으로 연산하여 환자의 안구상태를 파악하고, 초음파 치료를 위한 제1소자부(31)의 제어요소 설정값을 연산한다.The third element unit 34 provides temperature information of the patient's eyeball measured through the infrared sensor to the control operation unit 50, and the temperature information is utilized as a calculation data element of the control operation unit 50. That is, as will be described later, the control operation unit 50 comprehensively calculates not only the image and various data acquired from the second element unit 32, but also the temperature information acquired from the third element unit 34, so that the patient's The eye state is grasped, and a control element set value of the first element unit 31 for ultrasound treatment is calculated.

전원공급부(60)는 초음파소자부(30)에 전력을 공급하는 구성이다. 도 4에 도시된 바와 같이, 상기 초음파소자부(30)와 이격된 별도의 기술구성 형태로 적용될 수 있으며, 도시된 바와는 별개로 배터리 형태로 적용되어 일체로서 구성될 수 있다. The power supply unit 60 is configured to supply power to the ultrasonic element unit 30. As illustrated in FIG. 4, the ultrasonic element unit 30 may be applied in a separate technical configuration form spaced apart from each other, and may be configured as an integral part by being applied separately in the form of a battery.

제어연산부(50)는 초음파소자부(30)로부터 데이터를 받아 연산한 값을 바탕으로, 상기 초음파소자부(30)의 초음파 조사를 제어하는 구성이다. 보다 구체적으로는 제2소자부(32)로부터 획득한 데이터를 기초 환자의 안구 상태에 대한 이미지를 스캐닝하여 초음파 치료를 위한 제어요소들의 설정을 연산하고, 이에 따라서 제1소자부(31)가 치료용 초음파를 조사하도록 제어요소들을 조절하는 역할을 한다. 상기 제어연산부(50)를 통한 제어시스템에 대한 자세한 설명은 후술한다.The control operation unit 50 is configured to control ultrasonic irradiation of the ultrasonic element unit 30 based on a value calculated by receiving data from the ultrasonic element unit 30. More specifically, the data obtained from the second element unit 32 is scanned for an image of the eye condition of the basic patient to calculate the setting of control elements for ultrasound treatment, and accordingly, the first element unit 31 is treated It serves to adjust the control elements to irradiate the ultrasonic waves. A detailed description of the control system through the control operation unit 50 will be described later.

제어연산부(50)도 전원공급부(60)와 마찬가지로, 도 4에 도시된 바와 같이, 상기 초음파소자부(30)와 이격된 별도의 기술 구성형태로 적용될 수 있으며, 도시된 바와는 별개로 일체로서 구성될 수 있다. The control operation unit 50, like the power supply unit 60, as shown in FIG. 4, may be applied in a separate technical configuration form spaced apart from the ultrasonic element unit 30. Can be configured.

커넥터부(40)는 초음파소자부(30)이 전기적 연결이 되도록 하는 구성으로, 베이스필름부(10) 또는 커버필름부(20) 중 어느 하나의 일측에 위치한다. 즉, 상기 초음파소자부(30)를 전력을 공급받을 수 있도록 전원공급부(60)와 전기적으로 연결하며, 제어연산부(50)와 통신할 수 있도록 전기적으로 연결시키는 역할을 한다.The connector portion 40 is configured such that the ultrasonic element portion 30 is electrically connected, and is located on either side of the base film portion 10 or the cover film portion 20. That is, the ultrasonic element unit 30 is electrically connected to the power supply unit 60 so as to receive power, and serves to electrically connect the control operation unit 50 to communicate with it.

보다 구체적으로는 커넥터부(40)의 일측은 초음파소자부(30)를 향하여 양 방향으로 분리되어 일단(40a)은 제1소자부(31)와, 타단(40b)은 제2소자부(32)와 각각 전기적으로 연결된다. 또한, 상기 커넥터부(40)의 반대측은 별도로 이격되어 있거나 또는 일체로 형성된 전원공급부(60) 및 제어연산부(50)와 전기적으로 연결된다.More specifically, one side of the connector portion 40 is separated in both directions toward the ultrasonic element portion 30 so that one end 40a has a first element portion 31 and the other end 40b has a second element portion 32 ) And each of them is electrically connected. In addition, the opposite side of the connector portion 40 is separately spaced or electrically connected to the power supply unit 60 and the control operation unit 50 formed integrally.

도 6은 본 발명의 일 실시예에 의하여 복수 개의 소자에 대하여 독립적으로 신호가 전달되는 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘을 나타내는 블록도를, 도 7은 도 6의 이미지 스캔 방식을 이용한 안과용 초음파 치료기기의 메커니즘에 의한 치료용 초음파 조사형태를 도시한 모식도를 도시한다.FIG. 6 is a block diagram showing the mechanism of an ophthalmic ultrasound treatment apparatus using an image scanning method in which signals are independently transmitted to a plurality of devices according to an embodiment of the present invention, and FIG. 7 is an image scanning method of FIG. 6. It shows a schematic diagram showing the form of ultrasonic irradiation for treatment by the mechanism of the used ultrasonic treatment apparatus.

이하, 도 6 및 도 7를 참조하여 본 발명의 일 실시예에 의하여 복수 개의 소자에 대하여 독립적으로 신호가 전달되는 이미지 스캔 방식을 이용한 안과용 초음파 치료기기를 설명한다.Hereinafter, an ultrasound treatment apparatus for ophthalmology using an image scanning method in which signals are independently transmitted to a plurality of devices according to an embodiment of the present invention will be described with reference to FIGS. 6 and 7.

도 6에 도시된 바와 같이, 본 발명의 일 실시예에 의한 제1소자부(31)를 구성하는 복수 개의 소자는 각각의 독립적인 매치필터(314)와 이에 상응하는 지연선로(Delay line, 315)를 각각 포함하는 것을 특징으로 한다. 상기 지연선로(315)는 입력신호로부터 출력신호의 전달을 지연시키는 역할을 한다.As shown in Figure 6, a plurality of elements constituting the first element portion 31 according to an embodiment of the present invention each independent match filter 314 and the corresponding delay line (Delay line, 315) It characterized in that it includes each. The delay line 315 serves to delay the transmission of the output signal from the input signal.

즉, 도7에 도시된 바와 같이 본 발명의 지연선로(315)는 제어연산부(50)로부터 전달되는 제어신호가, 각각의 소자들의 매치필터(314)에 대하여 서로 다른 도달시기를 갖도록 하여, 조사되는 초음파의 방향 강도 등을 제어할 수 있다. 더불어, 상기 각각의 지연선로(315)는 상기 제어연산부(50)로부터 신호의 지연정도가 조절될 수 있다.That is, as illustrated in FIG. 7, the delay line 315 of the present invention is irradiated by allowing the control signals transmitted from the control operation unit 50 to have different arrival times for the match filters 314 of respective elements. The intensity of the direction of the ultrasonic wave can be controlled. In addition, the delay degree of a signal from the control operation unit 50 may be adjusted in each delay line 315.

그 결과 본 발명의 초음파 치료기기는 치료를 위한 음파를 조사하는 가로 또는 세로의 초점위치, 초점깊이 등을 적절하게 제어하여 안구, 수정체의 노안, 백내장 등을 치료할 수 있다. As a result, the ultrasound treatment apparatus of the present invention can treat the eyeball, lens presbyopia, cataract, etc. by appropriately controlling the horizontal or vertical focal position, depth of focus, etc. for irradiating sound waves for treatment.

도 8은 본 발명의 일 실시예에 의한 이미지 스캔 방식을 이용한 안과용 초음파 치료기기을 이용한 안과용 치료방법의 방법흐름도를 도시한다.8 illustrates a method flow diagram of an ophthalmic treatment method using an ophthalmic ultrasound treatment apparatus using an image scanning method according to an embodiment of the present invention.

이하, 도 8을 참조하여 본 발명의 제어연산부(50)의 초음파소자부(30)에 대한 제어시스템, 특히 안구의 노안치료를 위한 치료방법으로서의 제어시스템을 자세히 설명한다.Hereinafter, a control system for the ultrasonic element unit 30 of the control operation unit 50 of the present invention will be described in detail with reference to FIG. 8, in particular, a control system as a treatment method for presbyopic eye treatment.

본 발명에 따른 이미지 스캔 방식을 이용한 안과용 초음파 치료기기는 환자의 각막 상에 안구에 장착된다. 이후, 제어연산부(50)는 최초단계로서 안구의 노안상태를 검사하기 위한 초음파 스캔 단계(S10)에 해당하는 제어신호를 제2소자부(32)에 송출한다. The ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention is mounted on the eyeball on the cornea of a patient. Thereafter, as a first step, the control operation unit 50 transmits a control signal corresponding to the ultrasound scanning step S10 for checking the presbyopia state of the eyeball to the second element unit 32.

이에 따라, 상기 제2소자부(32)는 영상전송부(320)를 통해 이미지 스캔을 위한 전송 초음파를 제공하고, 이후 초음파변환기부(33)를 거친 이미지 스캔을 위한 수신 초음파가 영상수신부(330)를 통해 수신된다. 상기 제2소자부(32)는 위와 같이 획득한 이미지 스캐닝 데이터를 제어연산부(50)에 제공한다.Accordingly, the second element unit 32 provides transmission ultrasound for image scanning through the image transmission unit 320, and then receives ultrasound for image scanning through the ultrasonic converter unit 33, the image receiving unit 330. Is received through. The second element unit 32 provides the image scanning data acquired as above to the control operation unit 50.

제어연산부(50)는 위 이미지 스캐닝 데이터를 기초로 연산하여, 환자의 안구 상태에 대한 이미지 스캐닝을 한다. 이후, 상기 제어연산부(50)는 환자의 수정체에 대한 노안 위치 및 수준 등을 확인하는 수정체 노안 분석 단계(S20)를 거친다.The control operation unit 50 calculates an image based on the image scanning data, and scans the patient's eye condition. Thereafter, the control operation unit 50 undergoes a lens presbyopia analysis step (S20) for confirming the position and level of presbyopia for the patient's lens.

수정체 노안 분석 단계(S20) 이후, 제어연산부(50)는 제1소자부(31)에 전달하기 위한 제어신호를 도출한다. 보다 구체적으로는 획득한 수정체의 노안상태를 기초로 하여, 치료용 초음파의 초점영역, 초점영역의 강도, 펄스 반복주기, 펄스 폭, 음향 작동 주파수, 조사시간, 초점거리 등의 제어요소 중 어느 하나 이상을 설정하는 초음파 치료 조건 설정 단계(S30)에 이른다.After the lens presbyopia analysis step (S20), the control operation unit 50 derives a control signal for transmission to the first element unit 31. More specifically, based on the presbyopia of the acquired lens, any one of the control elements such as the focal region of the therapeutic ultrasound, the intensity of the focal region, pulse repetition period, pulse width, acoustic operating frequency, irradiation time, and focal length The ultrasonic treatment condition setting step (S30) for setting abnormalities is reached.

이때, 제어연산부(50)는 제1소자부(31)에 대하여 복수 개의 소자에 대한 제어신호의 도달시기를 각각 독립적으로 조절하여, 치료를 위한 음파를 조사하는 가로 또는 세로의 초점위치, 초점깊이 등을 적절하게 제어할 수 있다.At this time, the control operation unit 50 independently adjusts the arrival times of the control signals for the plurality of elements with respect to the first element portion 31, respectively, a horizontal or vertical focus position and depth of focus for irradiating sound waves for treatment. The back can be appropriately controlled.

이후, 제어연산부(50)는 설정된 제어신호를 제1소자부(31)에 송출하고, 위 제어신호에 의하여 설정된 치료요건에 따라 상기 제1소자부(31)가 치료용 초음파를 조사한다. 이에 따라 초음파변환기부(33)가 환자의 수정체의 필요한 위치에 에너지를 제공하여 노안 치료를 수행하는 초음파 치료 단계(S40)가 이루어 진다.Thereafter, the control operation unit 50 transmits the set control signal to the first element unit 31, and the first element unit 31 irradiates ultrasound for treatment according to the treatment requirements set by the above control signal. Accordingly, an ultrasound treatment step (S40) is performed in which the ultrasound transducer unit 33 provides energy at a required position of the patient's lens to perform presbyopia treatment.

초음파 치료 단계(S40)가 이루어지면, 제어연산부(50)는 제2소자부(32)에 대하여 수정체 노안 치료 효과 검사를 하기 위하여 초음파 스캔 단계(S50)에 해당하는 제어신호를 송출한다. 이로 인해 다시금 제2소자부(32)는 전술한 수정체 노안 분석 단계(S20)의 방법과 같이 이미지 스캐닝 영상 및 다양한 데이터를 수신하여, 이를 상기 제어연산부(50)에 제공한다.When the ultrasound treatment step (S40) is performed, the control operation unit 50 transmits a control signal corresponding to the ultrasound scanning step (S50) in order to examine the effect of treatment of lens presbyopia on the second element unit 32. For this reason, the second element unit 32 receives the image scanning image and various data as in the method of the lens presbyopia analysis step S20 described above, and provides it to the control operation unit 50.

제어연산부(50)는 위 이미지 스캐닝에 의한 영상 및 데이터를 기초로 하여, 환자 안구의 수정체 노안 치료효과를 확인하고, 추가적인 초음파 치료의 필요 여부를 판단하는 결과 분석 단계(S60)를 거치게 된다. 그 결과 추가적인 치료가 필요하다고 판단되는 경우에, 제어연산부(50)는 전술한 치료 조건 설정 단계(S30)부터 결과 분석 단계(S60)까지의 제어시스템을 반복 실행한다.The control operation unit 50 performs a result analysis step (S60) of determining the effect of treating the presbyopia of the patient's eye, based on the image and data by scanning the image above, and determining whether additional ultrasound treatment is necessary. As a result, when it is determined that additional treatment is necessary, the control operation unit 50 repeatedly executes the control system from the above-described treatment condition setting step (S30) to the result analysis step (S60).

전술한 바와 같이 본 발명에 따른 이미지 스캔 방식을 이용한 안과용 초음파 치료기기는, 환자의 수정체의 노안 위치 및 수준 등에 대한 영상 및 다양한 데이터를 취득하여 이에 따른 초음파 치료조건을 설정하게 되므로, 다양한 환자의 안구 환경에 따른 정밀하고 효율적인 안구, 수정체의 노안, 백내장 등의 초음파 치료를 가능케 한다.As described above, the ophthalmic ultrasound treatment apparatus using the image scanning method according to the present invention acquires images and various data on the presbyopia position and level of a patient's lens, and sets ultrasound treatment conditions accordingly. It enables precise and efficient ultrasound treatment according to the eye environment, presbyopia of the lens, and cataracts.

더불어, 전술한 초음파 치료 이후 다시금 환자의 수정체의 노안 위치 및 수준 등에 대한 영상 및 다양한 데이터를 취득하여, 해당 초음파 치료의 효과를 확인하고 재치료 여부를 점검하는 시스템을 통하여, 인체의 특히 민감한 부위의 안구 치료에 대한 완전성을 확보할 수 있다.In addition, after the above-described ultrasound treatment, the image and various data on the presbyopia position and level of the patient's lens are acquired again, and the system checks the effectiveness of the ultrasound treatment and checks for re-treatment. The completeness of the treatment can be ensured.

전술한 본 발명의 설명은 예시를 위한 것이며, 본 발명이 속하는 기술분야의 통상의 지식을 가진 자는 본 발명의 기술적 사상이나 필수적인 특징을 변경하지 않고서 다른 구체적인 형태로 쉽게 변형이 가능하다는 것을 이해할 수 있을 것이다. 그러므로 이상에서 기술한 실시예들은 모든 면에서 예시적인 것이며 한정적이 아닌 것으로 이해해야만 한다. 예를 들어, 단일형으로 설명되어 있는 각 구성 요소는 분산되어 실시될 수도 있으며, 마찬가지로 분산된 것으로 설명되어 있는 구성 요소들도 결합된 형태로 실시될 수 있다.The above description of the present invention is for illustration only, and a person having ordinary knowledge in the technical field to which the present invention pertains can understand that it can be easily modified into other specific forms without changing the technical spirit or essential features of the present invention. will be. Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive. For example, each component described as a single type may be implemented in a distributed manner, and similarly, components described as distributed may be implemented in a combined form.

본 발명의 범위는 후술하는 청구범위에 의하여 나타내어지며, 청구범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.The scope of the present invention is indicated by the following claims, and all modifications or variations derived from the meaning and scope of the claims and equivalent concepts should be interpreted to be included in the scope of the present invention.

부호의 설명Explanation of code

10: 베이스필름부10: base film section

20: 커버필름부20: cover film portion

30: 초음파소자부30: ultrasonic element unit

31: 제1소자부31: first element part

32: 제2소자부32: second element part

33: 초음파변환기부33: ultrasonic transducer unit

34: 제3소자부34: third element part

40: 커넥터부40: connector

50: 제어연산부50: control operation unit

60: 전원공급부60: power supply

310: 치료초음파 전송부310: therapeutic ultrasound transmission unit

311: 치료빔형성기311: Treatment beam forming machine

312: 제1펄스발생기312: first pulse generator

313: 제1증폭기313: first amplifier

314: 매치필터314: match filter

315: 지연선로315: delay line

320: 영상전송부320: video transmission unit

321: 전송빔형성기321: transmission beam former

322: 제2펄스발생기322: second pulse generator

323: 전송저역통과필터323: Transmission low pass filter

324: 제2증폭기324: second amplifier

330: 영상수신부330: image receiving unit

331: 저잡음증폭기331: low noise amplifier

332: 전압조정감쇄기332: voltage regulation attenuator

333: 이득증폭기333: gain amplifier

334: 수신저역통과필터334: received low pass filter

335: A/D 컨버터335: A/D converter

336: 수신빔형성기336: receiving beam forming machine

340: 트랜지스터340: transistor

Claims (7)

베이스필름부;Base film portion; 상기 베이스필름부와 전부 또는 일부가 중첩되는 커버필름부;A cover film part overlapping all or part of the base film part; 상기 베이스필름부와 상기 커버필름부의 사이에 소정의 거리를 두고 이격된 복수 개의 소자로 형성되며, 안구방향으로 초음파를 송수신하는 초음파소자부;An ultrasonic element portion formed of a plurality of elements spaced apart at a predetermined distance between the base film portion and the cover film portion, and transmitting and receiving ultrasonic waves in an eyeball direction; 상기 초음파소자부에 전력을 공급하는 전원공급부;A power supply unit supplying power to the ultrasonic element unit; 상기 초음파소자부를 제어하는 제어연산부; 및A control operation unit for controlling the ultrasonic element unit; And 상기 초음파소자부를 상기 제어연산부 및 상기 전원공급부를 전기적으로 연결시키는 커넥터부를 포함하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.An ophthalmic ultrasound treatment apparatus using an image scanning method, including a connector portion electrically connecting the ultrasonic element portion to the control operation portion and the power supply portion. 제1항에 있어서,According to claim 1, 상기 초음파소자부는, The ultrasonic element unit, 치료용 초음파를 조사하는 제1소자부와;A first element unit that irradiates therapeutic ultrasound; 이미지 스캐닝용 초음파를 송수신하는 제2소자부; 및A second element unit for transmitting and receiving ultrasound for image scanning; And 초음파 주파수 범위 내에서 전기적 에너지를 물리적 에너지로 변환하거나 또는 물리적 에너지를 전기적 에너지로 변환하 초음파변환기부를 더 포함하며, Further comprising an ultrasonic converter for converting electrical energy into physical energy within the ultrasonic frequency range or converting physical energy into electrical energy, 상기 제어연산부는 상기 제2소자부로부터의 스캔 정보를 전달받아 상기 제1소자가 치료용 초음파를 조사하는 제어요소를 설정하는 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.The control operation unit receives the scan information from the second element unit, characterized in that the first element is an ophthalmic ultrasound treatment apparatus using an image scanning method, characterized in that for setting a control element for irradiating ultrasound for treatment. 제2항에 있어서,According to claim 2, 상기 제2소자부는,The second element portion, 안구에 대하여 이미지 스캔을 위한 초음파 신호를 전송하는 영상전송부;An image transmitting unit that transmits an ultrasound signal for scanning an image of the eyeball; 안구에 초음파의 전송신호를 수신신호로 전환하는 트랜지스터; 및Transistor for converting the transmission signal of the ultrasound to the eye to the received signal; And 안구로부터 이미지 스캔을 위한 초음파 신호를 수신하는 영상수신부를 더 포함하는 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.And characterized in that it further comprises an image receiving unit for receiving an ultrasound signal for scanning the image from the eye, ultrasound treatment apparatus for ophthalmology using an image scanning method. 제3항에 있어서,According to claim 3, 상기 영상전송부는,The video transmission unit, 이미지 스캔을 위한 전송 초음파 빔을 발생시키는 전송빔형성기;A transmission beam former that generates a transmission ultrasonic beam for image scanning; 상기 이미지 스캔용 전송 초음파에 진동을 발생시키는 제2펄스발생기;A second pulse generator that generates vibrations in the transmission ultrasound for image scanning; 상기 이미지 스캔용 전송 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 전송저역통과필터; 및A transmission low pass filter for passing only frequency signals below a predetermined frequency in the transmission ultrasound for image scanning; And 상기 이미지 스캔용 전송 초음파를 증복시키는 제2증폭기를 더 포함하는 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기. And a second amplifier that amplifies the transmission ultrasound for image scanning. 제4항에 있어서,The method of claim 4, 상기 영상수신부는,The image receiving unit, 이미지 스캔용 수신 초음파의 신호에서 잡음이 최소화되도록 설계된 저잡음 증폭기;A low noise amplifier designed to minimize noise in the signal of the received ultrasound for image scanning; 상기 이미지 스캔용 수신 초음파의 신호의 전압을 전압조정 감쇄기;A voltage adjustment attenuator for the voltage of the signal of the received ultrasound for scanning the image; 프래그래맹이 가능한 이득증폭기;A gain amplifier capable of being flagged; 상기 이미지 스캔용 수신 초음파에서 기설정된 특정 주파수 이하의 주파수 신호만을 통과시키는 수신저역통과필터;A reception low pass filter for passing only frequency signals below a predetermined frequency in the reception ultrasound for image scanning; 상기 이미지 스캔용 수신 초음파를 아날로그 신호에서 디지털 신호로 전환하는 A/D 컨버터; 및An A/D converter that converts the received ultrasound for image scanning from an analog signal to a digital signal; And 이미지 스캔을 위한 수신 초음파 빔을 발생시키는 수신빔형성기를 더 포함하는 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.And characterized in that it further comprises a receiving beam forming machine for generating a receiving ultrasound beam for scanning an image, an ophthalmic ultrasound treatment apparatus using an image scanning method. 제2항에 있어서,According to claim 2, 상기 제1소자부는,The first element portion, 안구 치료용 초음파 빔을 생성하는 치료 초음파의 치료빔형성기;A therapeutic beam forming machine of therapeutic ultrasound to generate an ultrasound beam for eye treatment; 상기 치료용 초음파에 진동을 발생시키는 제1펄스발생기;A first pulse generator that generates vibrations in the therapeutic ultrasound; 상기 치료용 초음파를 증폭시키는 제1증폭기; 및A first amplifier to amplify the therapeutic ultrasound; And 입력된 상기 치료용 초음파의 신호를 정합시키는 매치필터를 포함하는 치료초음파 전송부가 구비되며,A therapeutic ultrasound transmission unit including a match filter that matches the input signal of the therapeutic ultrasound is provided, 상기 치료용 초음파는 저강도 집속형 초음파인 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.The ultrasound treatment is characterized in that the low intensity focused ultrasound, ophthalmic ultrasound treatment apparatus using an image scanning method. 제2항에 있어서,According to claim 2, 상기 제어연산부는,The control operation unit, 상기 제2소자부로부터 전달받은 스캔 정보로 안구의 수정체 노안 위치 및 정도를 연산하여,By calculating the position and degree of presbyopia of the lens of the eye with the scan information received from the second element, 상기 제 1소자부가 조사하는 치료용 초음파의 초점영역, 초점영역의 강도, 펄스 반복주기, 펄스 폭, 음향 작동 주파수, 조사시간, 초점거리 중 어느 하나 이상을 제어하되, Controlling any one or more of the focal region, the intensity of the focal region, the pulse repetition period, the pulse width, the acoustic operating frequency, the irradiation time, and the focal length of the therapeutic ultrasound irradiated by the first element unit, 상기 제1소자부에 대하여 복수 개의 소자에 대한 제어신호의 도달시기를 각각 독립적으로 조절하는 것을 특징으로 하는, 이미지 스캔 방식을 이용한 안과용 초음파 치료기기.An ultrasound treatment apparatus for ophthalmology using an image scanning method, characterized in that the arrival times of control signals for a plurality of elements are independently adjusted with respect to the first element portion.
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