WO2020198815A1 - Antiparasitic agent - Google Patents

Abstract

The invention relates to the pharmaceutical industry, specifically to the production of a combination medicinal product for treating parasitic diseases, primarily helminth infestations, of various etiology, in particular to agents on the basis of ethers of a herbal medicinal product for treating human parasitic diseases caused primarily by worms of various etiology, Giardia and trichomonas. The problem addressed by the proposed invention is that of producing an antiparasitic agent on the basis of medicinal plants, the agent encompassing all types of worms. The stated problem is solved in that the antiparasitic agent comprises 30 ml of castor oil to which are consecutively introduced the following official essential oils: clove, pumpkin, orange, black cumin, grapefruit, buckthorn and manuka, in the following ratio, in ml: 2-3 drops of clove, 2-3 drops of manuka, 2-3 drops of orange, 2-3 drops of grapefruit, 5 ml of pumpkin, 5 ml of buckthorn and 5 ml of black cumin. The essence of the proposed combination antiparasitic agent consists in that its action is extended to all types of worms.

Description

Anshparasitic agent

The invention relates to the pharmaceutical industry, namely to the creation of a medicinal collection for the treatment of parasitic diseases _" mainly hepsintoses, of various etiologies, in particular, to drugs based on esters of medicinal plant raw materials for the treatment of human parasitic diseases, caused mainly by helminths of various etiologies, lamblia and Trichomonas,

Liberation of a person from parasites, in particular helminths, is of great importance for strengthening and improving the body as a whole and curing diseases provoked by helminthiasis,

At the heart of many of gastrointestinal disorders (constipation, diarrhea, nausea, vomiting, stomach pain due enteritis or enterocolitis), respiratory diseases (from ARI to pneumonia), neurological diseases (from beznrichzhshosh _irritation: headaches, dizziness to nervous tics and even epileptic seizures), chronic fatigue syndrome, allergic reactions in the form of skin lesions, as well as mental disorders, infection with gelshty often lies. Helminth toxins have a depressing effect on the human circulatory system and cause! anemia, in especially severe cases, proceeding so acutely that blood cancer is diagnosed (Kornakhova ELE Parazitychelovska, St. Petersburg, 2002;

MullerR, WormsandhumaniJiseas.Oxon - Ncwjork, 2001

Known methods of expelling helminths from the human body with medicinal drugs, which are selectively act on one or another type of helminths, in addition, they are very toxic and have numerous side effects, as well as contraindications for a number of diseases, (Mapzhovsky M.D. Medicines, 2001; Zayats R.G., Rachkovokaa I. V., Karpov I.A. Fundamentals of general medical parasitology, 2002).

Known antite miytny means, which includes as active components walnuts, pumpkin seeds, wormwood, cloves and garlic (see T, L. Pilat et al. Kazakhstan register of biologically active food additives. Almaty :, Deovit, 2000 p, p. .204).

However, this collection has strongly pronounced astringent properties, which can prevent the excretion of worms with metabolic products, in addition, it is ineffective in dymbliosis.

The objective of the proposed invention is the creation of an antinuclear drug based on medicinal products, covering all types of helminths.

The task is solved by the fact that the anti-ramming agent contains 30 ml of castor asl * where sequentially entering the most important essential oils: cloves, pumpkin, orange, black cumin, grapefruit, sea buckthorn _* tea tree, the corresponding ratio, md; cloves 2-3 drops

tea tree 2-3 drops

orange 2-3 drops

grapefruit 2-Zhashsh

pumpkin 5ml

sea buckthorn 5 ppm

black cumin 5 ppm:

The essence of the antiparasitic collection is; in that its action applies to all types of helminths.

Consider the chemical and biologically active composition of the proposed medicinal plants: Clove - is a powerful drug, Clove action: bactericidal; anthelmintic antifungal pain reliever; antispasmodic; wound healing; carminative anticarcinogenic. Fragrant carnation is a component of Troicatka antiparasitic dietary supplement. Clove contains useful minerals: potassium, calcium, sodium, magnesium, phosphorus, iron, manganese, copper, selenium, zinc. A significant content of Omega-3 and Omega-6 in the field _and unsaturated fatty shots. 20% of one bud is an essential oil containing aromatic substances of eugenol, caryophiliae, shzaigay, etc. In the _first tamines of clove buds: provitamin A (beta-carotene), B vitamins (01, B2, B3 or PP, B4, B6, B9), vitamin C (ascorbic acid), vitamin E (tocopherol) and vitamin

Tea tree has a unique ashtaakter, antiviral and antifungal properties. All these qualities make it one of the most effective aytib tshv immunoassayers of natural origin. It consists of tea tree essential oil from 40% ^~ 5O% mo _st oterpenov, up to 40% diterpenes and from 3% to 15% of the lineal. If the percentage of cine-ode content is higher, then the oil can cause skin irritation ^. If the diterpenes in the oil are more than 30%, then this indicates its high efficiency.

Ether orange _D) m & sdayuno has ^{bactericidal,} notifying tonishrudoSch And ashiseshimsskihsh properties .. _Also, a good antispasmodic composition to antidspressazhg.Himnchssky aldehydes (u 'trawl), esters (metshshitra dates), alcohols ^(nerol), terpenes (limonene) ,

цинк, фтор), антиоксиданты,

клетчатка й: щрОтдаоВДШГрейифрут содержит также антиоксиданты, которые снижают уровень холестерина и улучшают пропорцию содержащихся HDL- и LDL- яипопротейЯов з8:/ us anfo/proUueeferapefrui html Grapefruit - The grapefruit pulp contains a large number of useful substances, including vitamins (A, PP, C, D. B1, B2, B9 ⁾ , minerals (potassium, magnesium, calcium, phosphorus, sodium, iodine, iron, cobalt, copper _, manganese,

zinc, fluorine), antioxidants,

Fiber nd: GREYFRONT GRAYFruit also contains antioxidants that reduce cholesterol levels and improve the proportion of HDL and LDL proteins contained in the proteins: / us anfo / proUueeferapefrui html

Pumpkin - despite the fact that pumpkin is 90% water, it contains many vitamins, amino acids, proteins, carbohydrates. In particular, the vegetable contains vitamins such as A, C, B, 0, PP, K, group B, and the rare vitamin TDshsva has a laxative effect, which has a good effect on the stomach and intestines of the ipaicr. It is recommended for removing cholesterol, toxins, toxins from the body. Pumpkin seeds are used to treat liver diseases, as an anthelmintic agent due to their high zinc content, as well as a lot of iron, cadium and magtsh.

Sea buckthorn - the chemical composition of sea buckthorn is unusually diverse. Fresh berries contain a large amount of ascorbic acid: - up to 300 mg per 100 g of a whole group of B vitamins, provitamin A, folic acid, which is especially important during pregnancy, tocopherol. From microslemeshuv it is worth highlighting - iron, magnesium, sulfur, boron, silicon. Of great value is sea buckthorn oil ~~~ fatty oil, which is contained in the seeds of sea buckthorn fruits: the berries have a complex composition and contain! almost all the vitamins known to science, Especially a lot of vitamin C in sea buckthorn, Useful properties - lowering the level of bad cholesterol (low lipoproteins gtot | dasti); strengthening the immune system; lowering the level of sugar; prophylaxis with autamine: osa (yyr8: // po12: a ¥ geb.sh)

Black cumin - black cumin oil is used as a natural cosmetic and as part of an antidote for snake bites, and they also ate this healthy herbal product and improve digestion, to get rid of worms, to improve the functioning of the liver, lungs and kidneys. Ancient Eastern medicine received black cumin oil thanks to the mention of it in the Koran (the Prophet Muhammad called black cumin oil "a remedy for all ailments except death"), and also thanks to the glorification of this natural product in the obese labors of Avicenna, who argued that black cumin helps a person not only fight diseases, but also helps to increase "vitality", overcoming fatigue and overwork. It should be noted that and just like many centuries ago, black gmina oil, which has various medicinal properties, is still widely used in Ayurveda (the traditional system of Indian Vedic medicine). The composition of black cumin oil contains unsaturated and saturated fatty acids, phospholipids (46% of which phosphatidylcholines account for), 15 amino acids (in so. and gsin), of which 8 are irreplaceable, carotenoids (precursors of vitamin A), vitamins B, D, C, B vitamins (B1, B2, B3, B6, B9), various macro- and microelements (potassium, sodium, phosphorus, calcium, manganese, iron, zinc, copper, selenium, nickel, etc.), phytosterols (beta-sitosherin, kamiester, stigmasterol, etc.), flavonoids, tannins , polysaccharides and monosaccharides (glucose, xylose, etc.), alkaloids, enzymes, saponins, triterpene saponins, essential oils (up to 1, 3%). (health stat) Castor oil is a vegetable oil obtained from the castor bean plant

a mixture of triglycerides of ricinoeic, dsnoleic and oleic acids.

Castor oil does not dry out, does not form a film. Most of it

(80%) are glycerides of viscous ricinoleic acid containing only one unsaturated bond in a huge molecule. The rest falls on glycerides of dshuyaic and oleic acids, (Wikipedia of castor oil, Antitr & zitargshY collection is prepared as follows

30 liters of cold-pressed castor oil are poured into a beaker, which is installed on a mechanical stirrer m, with constant stirring, essential oils are successively added: 5 ml of sea buckthorn, 5 ml of black cumin, Zml-pumpkin, then sequentially for 5 minutes add drops of: tea tree, orange, grapefruit, cloves, and the resulting mixture is stirred for 420 in.

When kspshzovashsh essential oils below the claimed limit, the agent yes manifests itself as an antiseptic, and above the claimed is not advisable.

The resulting oil mixture is poured into a glass container made of earth glass with a ground-in lid; it must be kept in a cool place.

The resulting product is orange-yellow in color, with a pleasant citrus scent of hrdaen -i year, it is possible to use it from 1 year to old age.

Reception of the proposed means is carried out as follows:

The dose of the developed agent is determined by the weight of a person is presented in the table

I 80 and up! 75 g j

The remedy is taken as follows:

At the first stage, the patient takes blood and drip for analysis.After analysis, the patient is given a dose of the drug on an empty stomach, depending on the weight of the person.

After taking, antispasmodic pains begin for 2-3 hours, which lead to emptying of the intestines, Then a strict diet is followed - it is impossible to eat meat, sweet, fatty dishes, flour, thereby the parasites are deprived of nutrition At this time, you can eat boiled potatoes, ayran, katyk etc. i drink a lot of water. In the evening before going to bed, you need to do an enema (for children, 3 teaspoons of teaspoonfuls of teaspoons for 1 liter of water, and for adults for 2 liters of water, spoons of teaspoons) to remove the remaining worms that chick behind the walls of the colon and rectum. A week later, a control repetition of the drug intake is carried out, and if the worms come out again, then this procedure is repeated for another week, followed by the serological test of blood and feces for helminth eggs, antibodies to lamblia, roundworm, oietorchoses, etc., and they take a tashke scraping around the anus for enterobiasis.

Sometimes, at the same time, helminths are displayed, which in medicine do not belong to any group,

Thus, the proposed method of extracting the helminth from the human body by means _> which not only removes parasites, but helps to raise its immune system.

Claims

CLAIM Antshtarazitar contains 30 ml of castor oil, into which offshore essential oils are added: cloves, PUMPKIN, orange, black cumin, grapefruit, sea buckthorn, tea tree, in an iridescent ratio, ml: cloves 2-3 drops tea tree ,, 2 ~ 3 k & shsh ape bsina, 2-3 drops grapefruit 2-3kg pumpkin 5ml sea buckthorn, 5 ml black cumin. 5 ppm