WO2020093629A1 - Liquid acquisition apparatus - Google Patents
Liquid acquisition apparatus Download PDFInfo
- Publication number
- WO2020093629A1 WO2020093629A1 PCT/CN2019/076603 CN2019076603W WO2020093629A1 WO 2020093629 A1 WO2020093629 A1 WO 2020093629A1 CN 2019076603 W CN2019076603 W CN 2019076603W WO 2020093629 A1 WO2020093629 A1 WO 2020093629A1
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- WIPO (PCT)
- Prior art keywords
- absorber
- liquid collection
- collection device
- liquid
- inner layer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
Definitions
- the invention relates to a liquid collection device, in particular to a liquid collection device used in the fields of medical inspection and drug detection.
- a commonly used method of collecting liquid is to put a liquid absorber into the collected part and take out the liquid absorber after a certain period of time for subsequent testing.
- the existing method is to fix the liquid absorption body on a sheet at the front end of a handle with an adhesive. This method has low efficiency and high cost, and the absorber can easily fall off during use.
- a liquid collection device in the prior art includes a funnel.
- a detachable outer tube is connected below the funnel.
- the inner tube is provided with an inner tube with a bottom facing upward and an opening facing down.
- the inner tube stores a preservation liquid.
- the space between the outer tube and the inner tube is the outer cavity, the outer cavity is connected to the funnel, the inner tube is connected to the funnel, and the bottom of the outer tube is provided with a step for closing the nozzle of the inner tube.
- the inner tube and the outer chamber are sealed and sealed to ensure that the storage solution will not leak out before the device is not used; when the outer tube is rotated away from the funnel, the inner tube and the outer chamber are unclogged , To ensure that the storage solution in the inner tube is mixed with the liquid in the outer chamber, so that the liquid can be stored for a long time, thereby ensuring the quality of the sample.
- the device allows the preservation liquid to flow out from the bottom of the inner tube and mix with the liquid, avoiding the pollution generated during the external addition process in the prior art.
- the structure of the liquid collection device is complicated, which is not conducive to manufacturing.
- Another saliva collection device in the prior art includes a liquid storage tube and a cover body.
- the liquid storage tube and the cover body can form an internal liquid storage space after being detached and connected.
- the liquid storage space is divided into two parts that are independent of each other.
- a piercing device is provided inside the cover body. The piercing device is used to pierce the isolation membrane after the liquid storage tube and the cover body are disconnected and connected.
- the liquid storage tube is made of transparent material or opaque material. This kind of liquid collecting device has many parts and is inconvenient to use.
- the present invention discloses a liquid collection device having a handle, a sampling rod, and an absorber wrapped on the outer peripheral wall of the sampling rod.
- the absorber includes an outer absorber and an inner layer
- the absorber, the inner peripheral wall of the outer absorber and the outer peripheral wall of the inner absorber are bonded to each other, the density of the outer absorber is less than the density of the inner absorber; the inner absorber has an axial socket that can be radially expanded and contracted .
- the density of the outer layer of the absorbent body is 0.035-0.20 g / cm 3
- the density of the absorbent inner layer is 0.15-0.45 g / cm3.
- the inner layer absorber has a wall thickness of 0.2 mm to 3.5 mm.
- both the outer layer absorber and the inner layer absorber are made of bicomponent fiber bonding.
- the axial compression strength of the absorber is greater than the radial compression strength.
- the liquid collection device further includes an upper baffle plate and a lower baffle plate provided at both ends of the sampling rod, and the upper baffle plate is fixedly connected to the end of the handle.
- the cross-sectional area of the lower baffle plate decreases from top to bottom, and the maximum cross-sectional area of the lower baffle plate is larger than the inner diameter of the jack and smaller than the inner diameter of the jack hole.
- the handle, the upper baffle, the sampling rod and the lower baffle plate are integrally formed.
- cross section of the lower baffle is circular.
- a liquid collection indicating member is provided between the absorber and the upper baffle.
- the liquid collection device can conveniently and quickly collect the liquid to be inspected, and it is easy to use the collected liquid sample for subsequent testing.
- FIG. 1 is a schematic cross-sectional view of a liquid collection device according to a first embodiment of the present invention
- FIG. 2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention.
- FIG. 3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention.
- FIG. 4 is a schematic structural diagram of a liquid collection container matched with a liquid collection device of a third embodiment of the present invention.
- FIG. 5 is a schematic structural diagram of a liquid collection device according to a fourth embodiment of the present invention.
- FIG. 6 is a schematic diagram of the A-A section in FIG. 5.
- the lower end or front end in the drawings refers to one end of the lower baffle, and the upper end or rear end refers to one end of the handle.
- the liquid collection device according to the first embodiment of the present invention has a handle 1, a sampling rod 13 and an absorber 2 wrapped on the outer peripheral wall of the sampling rod 13, the absorber 2 includes an outer layer absorber 21 and The inner layer absorber 22, the inner peripheral wall of the outer layer absorber 21 and the outer peripheral wall of the inner layer absorber 22 are bonded to each other, the density of the outer layer absorber 21 is less than the density of the inner layer absorber 22; the inner layer absorber 22 has Radial telescopic axial jack 23.
- the handle 1 in the present invention is generally a cylinder, and its function is to provide a sampler with a holding part for operating the liquid collection device.
- the handle 1 can also be provided in other three-dimensional shapes that are easy to hold, such as a square column.
- the sampling rod 13 in the present invention is preferably a cylindrical body, the outer peripheral wall of which is covered with an absorber 2 and can be directly or indirectly fixedly connected to the end of the handle 1.
- the sampling rod 13 can be injection molded from plastics such as polypropylene and polymethyl methacrylate.
- the handle 1 and the sampling rod 13 can be integrally injection-molded to reduce the parts to be assembled and simplify the assembly process.
- the main function of the outer layer absorber 21 according to the present invention is to absorb the liquid sample and release the liquid in subsequent tests.
- Suitable outer absorbent member density of 0.035-0.20 g / cm 3 high density, porosity of the outer layer of the absorbent body 21 is too small, will result in insufficient liquid absorption, in addition to a high density high hardness outer layer of the absorbent body 21 , May cause discomfort to the sampled.
- the density of the outer layer absorber 21 is too low, it is difficult to manufacture the outer layer absorber 21, and the capillary force of the outer layer absorber 21 having a too low density is insufficient, which may cause difficulty in sampling.
- the appropriate density is selected according to the application requirements.
- the outer layer absorber 21 is relatively soft and has sufficient capillary force. The sampling speed is fast and the collection volume is large. It is easy to release the collected liquid sample after radial extrusion.
- the main function of the inner layer absorber 22 according to the present invention is to support the softer outer layer absorber 21 and form an axial socket 23 that can be radially expanded and contracted, so that the absorber 2 and other components of the liquid collection device can be easily assembled Significantly reduce manufacturing costs and improve product reliability.
- the axially retractable axial insertion hole 23 can be expanded radially under the action of external force to increase the inner diameter of the insertion hole 23 to facilitate the insertion and assembly of the sampling rod 13. After the sampling rod 13 is assembled in place, the insertion hole 23 can be radially contracted and reset, thereby tightly covering the outer peripheral wall of the sampling rod 13 to form a tight assembly.
- the absorbent density of the inner layer 22 is 0.15-0.45 g / cm3. If the density of the inner layer absorber 22 is too low, the strength is insufficient, and the absorber may easily fall off the sampling rod 13. If the density of the inner layer absorber 22 is too high, the radial expansion and contraction of the socket will be too low, making it difficult to assemble.
- the wall thickness of the inner absorber 22 is 0.2-3.5 mm. Since the device is mainly used for collecting liquid samples of human body parts such as the oral cavity, nasal cavity, cervix, and vagina, a smaller absorber 2 is more suitable.
- the thinner wall thickness of the inner layer absorber 22 is helpful to reduce the diameter of the absorber and is beneficial to making a smaller liquid collection device; the larger wall thickness of the inner layer absorber 22 is beneficial to increase the strength of the inner layer absorber 22 It is suitable for applications that require high strength of the inner absorber 22, such as a liquid collection device that needs to squeeze out the liquid collected in the absorber 2.
- the absorber 2 includes a higher density inner layer absorber 22 and a lower density outer layer absorber 21, both of which are made of bicomponent fiber bonding, preferably a sheath-core structure or Bicomponent fiber with eccentric structure, such as polyethylene / polypropylene fiber, polyethylene / polyester fiber, etc., using chemically inert polyethylene as the skin layer of the fiber can reduce the adsorption of the measured component in the liquid sample and improve The sensitivity of subsequent tests.
- the outer layer absorber can be prevented from falling off during assembly or use.
- the axial compressive strength of the absorber 2 is greater than the radial compressive strength.
- the liquid collection device further includes an upper baffle 12 and a lower baffle plate 14 provided at both ends of the sampling rod 13.
- the upper baffle 12 is fixedly connected to the end of the handle 1.
- the cross-sectional area of the lower baffle plate 14 decreases from top to bottom.
- the maximum cross-sectional area of the lower baffle plate 14 is larger than the inner diameter of the insertion hole 23 and smaller than the maximum expanded inner diameter of the insertion hole 23.
- the handle 1, the sampling rod 13, the upper baffle 12 and the lower baffle 14 are integrally formed, preferably by injection molding.
- the absorber 2 is used to absorb the liquid to be detected, and the absorber 2 is provided with an axial socket that can expand and contract radially. Since the cross section of the lower baffle 14 decreases from top to bottom, the maximum cross-sectional area of the lower baffle plate 14 It is larger than the inner diameter of the jack 23 and smaller than the largest expanded inner diameter of the jack 23.
- the cross section of the lower end of the lower baffle 14 is set to be smaller than the cross section of the insertion hole 23 in the inner layer absorber 22, and when the lower baffle 14 is inserted into the insertion hole 23 of the inner layer absorber 22, the insertion hole 23 is radially supported Open, so that the lower baffle 14 and the lower part of the sampling rod 13 can smoothly pass through the insertion hole 23, and when the lower baffle 14 completely passes through the insertion hole 23, the insertion hole 23 retracts radially. Since the maximum cross section of the lower baffle plate 14 is larger than the cross section of the insertion hole 23, the absorber 2 cannot escape from the lower baffle plate. After the liquid sample is collected, it can be directly used for subsequent testing.
- the cross section of the lower baffle plate 14 is preferably a circular or nearly circular polygon.
- the longitudinal section of the lower baffle plate 14 is preferably trapezoidal, arc-shaped, or the like. In this embodiment, the longitudinal section of the lower baffle plate 14 is trapezoidal.
- FIG. 2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention.
- the structure of this embodiment is similar to that of the first embodiment, and the same parts as those of the first embodiment will not be repeated in the description of this embodiment.
- the front end of the absorber 2 is formed into a spherical crown shape, and the wall thickness of the inner absorber 22 is 0.2 mm. If the strength of the inner absorber 22 needs to be increased, The wall thickness of the inner layer absorber 22 is appropriately increased.
- the liquid collection device of this embodiment is suitable for collecting samples in a small and sensitive human body part. For example, nasal cavity, cervix, vagina, etc.
- an indicator part 3 is provided between the upper end of the absorber 2 and the upper baffle 12, such as a protonized discoloration test paper, which can observe the collection state of the liquid sample by the absorber in real time during sampling to facilitate judgment Whether the sample collection has been completed.
- the longitudinal cross section of the lower baffle plate 14 is provided in an arc shape.
- FIG. 3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention.
- the structure of this embodiment is similar to that of the first embodiment, and the same parts as those of the first embodiment will not be repeated in the description of this embodiment.
- this embodiment is similar to the first embodiment.
- Liquid collection apparatus according to the present embodiment is used in the oral cavity, the saliva for the detection of drug abuse, the outer layer 21 of the absorbent member density of 0.08 g / cm 3 or so, the density of the inner layer absorbent body 22 is 0.35 g / cm 3, the wall The thickness is 1.5 mm, so that the inner layer absorber 22 has high strength.
- the longitudinal section of the lower baffle plate 14 is trapezoidal.
- the fiber arrangement direction in the process of manufacturing the absorber 2, can be controlled so that the axial compressive strength of the absorber 2 is greater than the radial compressive strength.
- FIG. 4 is a schematic structural diagram of a liquid collection container matched with a liquid collection device of a third embodiment of the present invention. As shown in FIG. 4, when the absorber 2 absorbs enough liquid, insert the matching liquid collection container 4 as shown in FIG. 4, and press down on the handle 1 to radially compress the absorber 2, thereby compressing the absorber 2 inside. The liquid is squeezed into the liquid collection container 4.
- the liquid collection container 4 used in conjunction with the liquid collection device shown in FIG. 3 includes a liquid collection chamber 41, and a liquid compression chamber 41 disposed in the liquid collection chamber 41 for radially compressing the absorber 2 Compression department.
- the compression portion includes a conical introduction port 42, a radial compression chamber 43 provided at the lower part of the introduction port 42, and a liquid discharge port 44 provided near the junction of the introduction port 42 and the radial compression chamber 43.
- the liquid discharge port 44 communicates with the liquid collection chamber 41.
- the diameter of the upper baffle 2 is substantially equal to the diameter of the absorber 2 after fully radial compression, the inner diameter of the radial compression chamber 43 is slightly larger than the diameter of the absorber 2 after fully radial compression, and the maximum cross-sectional diameter of the lower baffle plate 14 is smaller than the absorption The diameter of the body 2 after fully radial compression.
- the upper baffle 12 is provided to have greater strength so as to facilitate pressing the absorber 2 into the liquid collection container 4.
- the handle 1 presses the absorber 2 into the conical inlet 42 of the liquid collection container 4, and the absorber 2 is gradually compressed radially until it is pressed into the radial compression cavity 43.
- the absorber 2 is sufficiently compressed in the radial direction, the absorbed liquid is fully released, and flows into the liquid collection chamber 41 through the liquid discharge port 44, thereby completing the liquid collection work.
- the collected liquid sample is used for subsequent detection.
- FIG. 5 is a schematic cross-sectional view of a liquid collection device according to a fourth embodiment of the present invention.
- the structure of this embodiment is similar to that of the first embodiment, and the same parts as the first embodiment will not be repeated in the description of this embodiment.
- this embodiment is similar to the first embodiment.
- the liquid collection device of this embodiment is used to collect saliva in the oral cavity for the detection of diseases such as acquired immunodeficiency.
- the absorber needs to rub the gingival region to obtain some epithelial cells, for example, to detect AIDS through oral sampling.
- the density of the absorbent layer 21 was 0.20 g / cm 3, the density of the inner layer absorbent body 22 is 0.45 g / cm 3, the thickness is set to 2mm-3.5mm, so that the absorbent body has a high strength.
- the lower end of the thickened handle 1 also serves as the upper baffle 12 and fixes the absorber 2 together with the arc-shaped lower baffle plate 14.
- FIG. 6 is a schematic diagram of the A-A section in FIG. 5.
- the cross-sectional profile of the outer layer absorber 21 is tooth-shaped, so as to increase the effect of epithelial cells when rubbing the gums.
- the liquid collection device according to the present invention has a simple structure and is easy to manufacture, and uses the radially retractable axial insertion hole 23 made of the two-component fibers bonded in the absorber 2 to fix the absorber 2 Between the upper baffle 12 and the lower baffle 14, the manufacturing cost is greatly reduced and the absorber will not fall off during use.
- the liquid collection device of the invention can be widely used in various medical detection occasions, and has good social significance and economic value.
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Abstract
Description
本发明涉及一种液体采集装置,特别涉及医学检验和毒品检测领域中使用的液体采集装置。The invention relates to a liquid collection device, in particular to a liquid collection device used in the fields of medical inspection and drug detection.
在医学检验和毒品检测领域,血液、尿液和唾液的检测较为常见。采集待分析液体样品是检测过程中的一个环节。常用的一种采集液体的方法是将一个液体吸收体放入被采集部位,经过一定时间后取出液体吸收体,用于后续测试。为便于操作,现有的方法是用粘结剂将液体吸收体固定在一个手柄前端的薄片上。此方法效率低、成本高,并且吸收体在使用过程中容易脱落。In the field of medical testing and drug testing, blood, urine and saliva testing are more common. Collecting the liquid sample to be analyzed is a link in the testing process. A commonly used method of collecting liquid is to put a liquid absorber into the collected part and take out the liquid absorber after a certain period of time for subsequent testing. In order to facilitate the operation, the existing method is to fix the liquid absorption body on a sheet at the front end of a handle with an adhesive. This method has low efficiency and high cost, and the absorber can easily fall off during use.
现有技术中的一种液体采集装置,该装置包括漏斗,漏斗下方连接有可拆卸的外管,外管内套设有底部朝上、开口朝下设置的内管,内管内存放有保存液,外管与内管之间的空间为外腔室,外腔室与漏斗连通,内管与漏斗相连,外管底部设置有用于将内管管口封闭的台阶。当外管和漏斗旋紧时,内管和外腔室之间密闭隔离,确保该装置在未使用之前,保存液不会泄露出来;当外管旋离漏斗时,内管与外腔室疏通,确保内管中的保存液与外腔室的液体混合,使液体长期保存,进而保证样品的质量。该装置使保存液从内管底部流出与液体混合,避免现有技术中从外部加入过程中产生的污染。然而,该液体采集装置结构复杂,不利于制造生产。A liquid collection device in the prior art includes a funnel. A detachable outer tube is connected below the funnel. The inner tube is provided with an inner tube with a bottom facing upward and an opening facing down. The inner tube stores a preservation liquid. The space between the outer tube and the inner tube is the outer cavity, the outer cavity is connected to the funnel, the inner tube is connected to the funnel, and the bottom of the outer tube is provided with a step for closing the nozzle of the inner tube. When the outer tube and the funnel are tightened, the inner tube and the outer chamber are sealed and sealed to ensure that the storage solution will not leak out before the device is not used; when the outer tube is rotated away from the funnel, the inner tube and the outer chamber are unclogged , To ensure that the storage solution in the inner tube is mixed with the liquid in the outer chamber, so that the liquid can be stored for a long time, thereby ensuring the quality of the sample. The device allows the preservation liquid to flow out from the bottom of the inner tube and mix with the liquid, avoiding the pollution generated during the external addition process in the prior art. However, the structure of the liquid collection device is complicated, which is not conducive to manufacturing.
现有技术中的另一种唾液采集装置,包括储液管和盖体,储液管和盖体可在拆卸连接后形成内部储液空间,储液空间内部还设有隔离膜,隔离膜将储液空间分割为彼此独立的两部分,盖体内部设有刺穿装置,刺穿装置用于在储液管和盖体拆卸连接后刺破隔离膜。储液管为透明材质或不透明材质制成。该种液体采集装置部件较多,使用不便。Another saliva collection device in the prior art includes a liquid storage tube and a cover body. The liquid storage tube and the cover body can form an internal liquid storage space after being detached and connected. There is also an isolation membrane inside the liquid storage space. The liquid storage space is divided into two parts that are independent of each other. A piercing device is provided inside the cover body. The piercing device is used to pierce the isolation membrane after the liquid storage tube and the cover body are disconnected and connected. The liquid storage tube is made of transparent material or opaque material. This kind of liquid collecting device has many parts and is inconvenient to use.
发明内容Summary of the invention
为了解决现有技术中存在的上述技术问题,本发明公开了一种液体采集装置,具有手柄、采样杆和包覆在采样杆外周壁上的吸收体,吸收体包括外层吸收体和内层吸收体,外 层吸收体的内周壁和内层吸收体的外周壁互相粘结,外层吸收体的密度小于内层吸收体的密度;内层吸收体具有可径向伸缩的轴向插孔。In order to solve the above-mentioned technical problems in the prior art, the present invention discloses a liquid collection device having a handle, a sampling rod, and an absorber wrapped on the outer peripheral wall of the sampling rod. The absorber includes an outer absorber and an inner layer The absorber, the inner peripheral wall of the outer absorber and the outer peripheral wall of the inner absorber are bonded to each other, the density of the outer absorber is less than the density of the inner absorber; the inner absorber has an axial socket that can be radially expanded and contracted .
进一步,外层吸收体的密度为0.035-0.20克/厘米 3,内层吸收体的密度为0.15-0.45克/厘米 3。 Further, the density of the outer layer of the absorbent body is 0.035-0.20 g / cm 3, the density of the absorbent inner layer is 0.15-0.45 g / cm3.
进一步,内层吸收体的壁厚为0.2毫米到3.5毫米。Further, the inner layer absorber has a wall thickness of 0.2 mm to 3.5 mm.
进一步,外层吸收体和内层吸收体均由双组分纤维粘结制成。Further, both the outer layer absorber and the inner layer absorber are made of bicomponent fiber bonding.
进一步,吸收体的轴向压缩强度大于径向压缩强度。Further, the axial compression strength of the absorber is greater than the radial compression strength.
进一步,液体采集装置还包括设置在采样杆两端的上挡板和下档板,上挡板与手柄的端部固定连接。Further, the liquid collection device further includes an upper baffle plate and a lower baffle plate provided at both ends of the sampling rod, and the upper baffle plate is fixedly connected to the end of the handle.
进一步,下档板的横截面积从上到下递减,下档板的最大横截面积大于插孔的内径,并小于插孔的最大扩张的内径。Further, the cross-sectional area of the lower baffle plate decreases from top to bottom, and the maximum cross-sectional area of the lower baffle plate is larger than the inner diameter of the jack and smaller than the inner diameter of the jack hole.
进一步,手柄、上挡板、采样杆和下档板一体成型。Further, the handle, the upper baffle, the sampling rod and the lower baffle plate are integrally formed.
进一步,下挡板的横截面为圆形。Further, the cross section of the lower baffle is circular.
进一步,吸收体和上挡板之间设置液体采集指示部件。Further, a liquid collection indicating member is provided between the absorber and the upper baffle.
如上,本发明涉及的液体采集装置可方便、快速采集需要检验的液体,并容易将采集到液体样品用于后续测试。As mentioned above, the liquid collection device according to the present invention can conveniently and quickly collect the liquid to be inspected, and it is easy to use the collected liquid sample for subsequent testing.
为了使本发明的上述内容更明显易懂,下文特举优选实施例,并结合附图,作详细说明如下。In order to make the above content of the present invention more obvious and understandable, preferred embodiments are described in detail below in conjunction with the accompanying drawings, which are described in detail below.
下面将结合附图介绍本发明。The present invention will be described below with reference to the drawings.
图1为根据本发明第一实施例的液体采集装置的剖面示意图;1 is a schematic cross-sectional view of a liquid collection device according to a first embodiment of the present invention;
图2为根据本发明第二实施例的液体采集装置的剖面示意图;2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention;
图3为根据本发明第三实施例的液体采集装置的剖面示意图;3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention;
图4是与本发明的第三实施例的液体采集装置配套的液体收集容器的结构示意图;4 is a schematic structural diagram of a liquid collection container matched with a liquid collection device of a third embodiment of the present invention;
图5为根据本发明第四实施例的液体采集装置的结构示意图;5 is a schematic structural diagram of a liquid collection device according to a fourth embodiment of the present invention;
图6为为图5中A-A剖面的示意图。FIG. 6 is a schematic diagram of the A-A section in FIG. 5.
以下由特定的具体实施例说明本发明的实施方式,本领域技术人员可由本说明书所揭 示的内容轻易地了解本发明的优点及功效。The following describes the implementation of the present invention by specific specific examples. Those skilled in the art can easily understand the advantages and effects of the present invention from the content disclosed in this specification.
需说明的是,在本发明中,附图中的下端或前端指下挡板的一端,上端或后端是指手柄的一端。It should be noted that in the present invention, the lower end or front end in the drawings refers to one end of the lower baffle, and the upper end or rear end refers to one end of the handle.
现在参考附图介绍本发明的示例性实施方式,然而,本发明可以用许多不同的形式来实施,并且不局限于此处描述的实施例,提供这些实施例是为了详尽地且完全地公开本发明,并且向所属技术领域的技术人员充分传达本发明的范围。对于表示在附图中的示例性实施方式中的术语并不是对本发明的限定。在附图中,相同的单元/元件使用相同的附图标记。Exemplary embodiments of the present invention will now be described with reference to the drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. These embodiments are provided to disclose the present invention in detail and completely Invention, and fully convey the scope of the invention to those skilled in the art. The terminology shown in the exemplary embodiments in the drawings does not limit the present invention. In the drawings, the same units / elements use the same reference numerals.
除非另有说明,此处使用的术语包括科技术语对所属技术领域的技术人员具有通常的理解含义。另外,可以理解的是,以通常使用的词典限定的术语,应当被理解为与其相关领域的语境具有一致的含义,而不应该被理解为理想化的或过于正式的意义。Unless otherwise stated, the terms used herein include scientific and technical terms that have a commonly understood meaning to those skilled in the art. In addition, it is understandable that terms defined in commonly used dictionaries should be understood to have the same meaning as the context of their related fields, and should not be understood as idealized or overly formal.
第一实施例First embodiment
图1是根据本发明第一实施例的液体采集装置的剖面示意图。如图1所示,根据本发明第一实施例的液体采集装置,具有手柄1、采样杆13和包覆在采样杆13外周壁上的吸收体2,吸收体2包括外层吸收体21和内层吸收体22,外层吸收体21的内周壁和内层吸收体22的外周壁互相粘结,外层吸收体21的密度小于内层吸收体22的密度;内层吸收体22具有可径向伸缩的轴向插孔23。1 is a schematic cross-sectional view of a liquid collection device according to a first embodiment of the present invention. As shown in FIG. 1, the liquid collection device according to the first embodiment of the present invention has a
本发明中的手柄1通常为圆柱体,作用是为采样者提供操作液体采集装置的握持部位。当然,手柄1也可以设置为其它便于握持的立体形状,例如方柱体等。The
本发明中的采样杆13优选为圆柱体,其外周壁上包覆有吸收体2,可以与手柄1的端部直接或者间接地固定连接。采样杆13可以用聚丙烯、聚甲基丙烯酸甲酯等塑料注塑成型。特别地,手柄1和采样杆13可以一体注塑成型,以减少装配的零部件、简化装配工艺。The
根据本发明的外层吸收体21的主要功能是吸收液体样品,并且在后续测试中把液体释放出来。合适的外层吸收体密度为0.035-0.20克/厘米
3,密度过高,外层吸收体21的孔隙率过小,会导致吸液量不足,此外密度高的外层吸收21体硬度偏高,可能使被采样者造成不适。外层吸收体21密度过低时外层吸收体21难以制造,并且密度过低的外层吸收体21毛细力不足,可能造成采样困难。根据应用要求选择合适的密度,外层吸收体21比较柔软并具有足够的毛细力,采样速度快,采集量大,并且容易经径向挤压后将采集到 的液体样品释放出来。
The main function of the
根据本发明的内层吸收体22的主要功能是支撑较软的外层吸收体21,并形成可径向伸缩的轴向插孔23,使吸收体2和液体采集装置的其它部件易于组装,大幅降低制造成本并提高产品的可靠性。可径向伸缩的轴向插孔23可在外力的作用下径向扩张,以增大插孔23的内径后方便采样杆13插入组装。在采样杆13装配到位后,插孔23可以径向收缩复位,从而紧紧地包覆采样杆13的外周壁,形成紧密装配。The main function of the
内层吸收体22的密度为0.15-0.45克/厘米
3。如果内层吸收体22的密度过低,其强度不足,容易使吸收体从采样杆13脱落。内层吸收体22的密度过高会导致插孔的径向伸缩性过低,难以组装。内层吸收体22的壁厚为0.2-3.5mm,由于本装置主要用于人体部位如口腔、鼻腔、子宫颈、阴道等的液体样品采集,较小的吸收体2较为合适。较薄的内层吸收体22壁厚有利于减小吸收体的直径,有利于制作较小的液体采集装置;较大的内层吸收体22壁厚则有利于增加内层吸收体22的强度,适合制作对内层吸收体22强度要求较高的应用,如需要将吸收体2中采集到的液体挤出的液体采集装置。
The absorbent density of the
根据本发明的液体采集装置,吸收体2包括较高密度的内层吸收体22和较低密度的外层吸收体21,两者均由双组分纤维粘结制成,优选皮芯结构或偏芯结构的双组分纤维,如聚乙烯/聚丙烯纤维,聚乙烯/聚酯纤维等,用化学惰性的聚乙烯为纤维的皮层,可以减少对液体样品中的被测成份的吸附,提高后续测试的灵敏度。将外层吸收体21的内壁和内层吸收体22的外壁互相粘结,可以避免组装或使用过程中外层吸收体脱落。According to the liquid collecting device of the present invention, the
根据本发明的液体采集装置,吸收体2的轴向压缩强度大于径向压缩强度。通过这种结构,可以采用径向压缩的方式将吸收体2中采集到的液体挤出。According to the liquid collecting device of the present invention, the axial compressive strength of the
液体采集装置还包括设置在采样杆13两端的上挡板12和下档板14,上挡板12与手柄1的端部固定连接。The liquid collection device further includes an
下档板14的横截面积从上到下递减,下档板14的最大横截面积大于插孔23的内径,并小于插孔23的最大扩张的内径。The cross-sectional area of the
为简化组装工序、降低成本,本实施例中将手柄1、采样杆13、上挡板12和下挡板14一体成型,优选采用注塑的方式。吸收体2用于对待检测液体进行吸收,吸收体2上设置有可径向伸缩的轴向插孔,由于下挡板14的横截面从上到下递减,下档板14的最大横截面积大于插孔23的内径,并小于插孔23的最大扩张的内径。优选,将下挡板14的下端横截面设置为小于内层吸收体22中的插孔23横截面,当下挡板14插入内层吸收体22的插孔23时,插孔23被径向撑开,使下挡板14和采样杆13的下部能顺利穿过插孔23, 当下挡板14完全穿过插孔23后,插孔23径向回缩。由于下挡板14的最大横截面大于插孔23的横截面,使吸收体2无法从下挡板脱出。液体样品采样完成后,可直接用于后续测试。In order to simplify the assembly process and reduce costs, in this embodiment, the
下挡板14的横截面优选为圆形或近似圆形的多边形。下挡板14的纵截面优选为梯形、圆弧形或类似的形状。在本实施例中,下档板14的纵截面设置为梯形。The cross section of the
第二实施例Second embodiment
图2是根据本发明第二实施例的液体采集装置的剖面示意图。本实施例与第一实施例结构相似,与第一实施例相同的部分在本实施例的描述中不再赘述。2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention. The structure of this embodiment is similar to that of the first embodiment, and the same parts as those of the first embodiment will not be repeated in the description of this embodiment.
如图2所示,本实施例的液体采集装置中,吸收体2的前端被制成球冠状,内层吸收体22的壁厚为0.2mm,如果需要增加内层吸收体22的强度,可以适当增加内层吸收体22的壁厚。本实施例的液体采集装置适合于在空间较小、较敏感的人体部位采集样品。例如鼻腔、子宫颈、阴道等部位。As shown in FIG. 2, in the liquid collection device of this embodiment, the front end of the
本实施例的液体采集装置中,在吸收体2的上端和上挡板12之间设置指示部件3,如质子化变色试纸,可以在采样时实时观察吸收体对液体样品的采集状态,便于判断样品采集是否已经完成。In the liquid collection device of this embodiment, an
在本实施例中,下档板14的纵截面设置为圆弧形。In the present embodiment, the longitudinal cross section of the
第三实施例Third embodiment
图3是根据本发明第三实施例的液体采集装置的剖面示意图。本实施例与第一实施例结构相似,与第一实施例相同的部分在本实施例的描述中不再赘述。3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention. The structure of this embodiment is similar to that of the first embodiment, and the same parts as those of the first embodiment will not be repeated in the description of this embodiment.
如图3所示,本实施例与第一实施例相似。本实施例的液体采集装置用于在口腔内采集唾液用于毒品滥用检测,外层吸收体21的密度为0.08克/厘米
3左右,内层吸收体22的密度为0.35克/厘米
3,壁厚为1.5mm,使内层吸收体22具有较高的强度。在本实施例中,下档板14的纵截面设置为梯形。
As shown in FIG. 3, this embodiment is similar to the first embodiment. Liquid collection apparatus according to the present embodiment is used in the oral cavity, the saliva for the detection of drug abuse, the
在本实施例中,在制造吸收体2的过程中,可以控制纤维排列方向使吸收体2的轴向压缩强度大于径向压缩强度。In this embodiment, in the process of manufacturing the
图4是与本发明的第三实施例的液体采集装置配套的液体收集容器的结构示意图。如图4所示,当吸收体2吸收足够的液体后,插入如图4所示的配套的液体收集容器4,向下按压手柄1使得吸收体2径向压缩,从而将吸收体2内的液体挤入至液体收集容器4中。FIG. 4 is a schematic structural diagram of a liquid collection container matched with a liquid collection device of a third embodiment of the present invention. As shown in FIG. 4, when the
具本而言,如图4示,与图3所示的液体采集装置配合使用的液体收集容器4包括液体收集室41,以及配置在液体收集室41中的用于径向压缩吸收体2的压缩部。该压缩部包括圆锥形导入口42、设置在导入口42下部的径向压缩腔43和设置在导入口42和径向压缩腔43交界处附近的液体排出口44。液体排出口44与液体收集室41连通。上挡板2的直径基本等于吸收体2充分径向压缩后的直径,径向压缩腔43的内径略大于吸收体2充分径向压缩后的直径,下档板14的最大横截面直径小于吸收体2充分径向压缩后的直径。上挡板12设置为具有较大的强度,以便于将吸收体2按压入液体收集容器4。Specifically, as shown in FIG. 4, the
当吸收体2吸收足够的液体后,手柄1将吸收体2压入液体收集容器4的圆锥形导入口42,吸收体2逐渐径向压缩直到压入径向压缩腔43中。在径向压缩腔43中,吸收体2得到充分的径向压缩,所吸收的液体被充分释放,并通过液体排出口44流入液体收集室41,从而完成液体的采集工作。收集到的液体样品用于后续的检测。After the
第四实施例Fourth embodiment
图5是根据本发明第四实施例的液体采集装置的剖面示意图。本实施例与第一实施例结构相似,与第一实施例相同的部分在本实施例的描述中不再赘述5 is a schematic cross-sectional view of a liquid collection device according to a fourth embodiment of the present invention. The structure of this embodiment is similar to that of the first embodiment, and the same parts as the first embodiment will not be repeated in the description of this embodiment.
如图5所示,本实施例与第一实施例相似。本实施例的液体采集装置用于在口腔中采集唾液用于检测获得性免疫缺陷等疾病,在采集唾液的过程中吸收体需要摩擦牙龈部位以获取部分上皮细胞,例如通过口腔取样检测艾滋病等。As shown in FIG. 5, this embodiment is similar to the first embodiment. The liquid collection device of this embodiment is used to collect saliva in the oral cavity for the detection of diseases such as acquired immunodeficiency. In the process of collecting saliva, the absorber needs to rub the gingival region to obtain some epithelial cells, for example, to detect AIDS through oral sampling.
外层吸收体21的密度为0.20克/厘米
3,内层吸收体22的密度为0.45克/厘米
3,壁厚设置为2mm-3.5mm,从而使吸收体具有较高的强度。本实施例中,加粗的手柄1下端兼作为上挡板12,与圆弧形的下档板14共同固定吸收体2。
The density of the
图6为图5中A-A剖面的示意图。在本实施例中,外层吸收体21的横截面轮廓为齿状,以增加摩擦牙龈时获取上皮细胞的效果。FIG. 6 is a schematic diagram of the A-A section in FIG. 5. In this embodiment, the cross-sectional profile of the
综上,本发明所涉及的液体采集装置结构简单、制造便捷、利用吸收体2中设置的由双组分纤维粘结制成的径向可伸缩的轴向插孔23,将吸收体2固定在上挡板12和下挡板14之间,极大地降低了制造成本,并确保吸收体在使用过程中不会脱落。本发明的液体采集装置可以广泛应用了各种医学检测场合,具有很好的社会意义和经济价值。In summary, the liquid collection device according to the present invention has a simple structure and is easy to manufacture, and uses the radially retractable
上述实施例仅例示性说明本发明的原理及其功效,而非用于限制本发明。任何本领域技术人员皆可在不违背本发明的精神及范畴下,对上述实施例进行修饰或改变。因此,本领域技术人员在未脱离本发明所揭示的精神与技术思想下所完成的一切等效修饰或改变, 仍应由本发明的权利要求所涵盖。The above-mentioned embodiments only exemplarily illustrate the principle and efficacy of the present invention, and are not intended to limit the present invention. Any person skilled in the art may modify or change the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or changes made by those skilled in the art without departing from the spirit and technical ideas disclosed in the present invention should still be covered by the claims of the present invention.
Claims (10)
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| CN201811335495.8A CN111175076B (en) | 2018-11-10 | 2018-11-10 | Liquid collecting device |
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