WO2019170060A1 - Image authentication-based medical image labeling method and device, user terminal, and computer readable storage medium - Google Patents
Image authentication-based medical image labeling method and device, user terminal, and computer readable storage medium Download PDFInfo
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- WO2019170060A1 WO2019170060A1 PCT/CN2019/076896 CN2019076896W WO2019170060A1 WO 2019170060 A1 WO2019170060 A1 WO 2019170060A1 CN 2019076896 W CN2019076896 W CN 2019076896W WO 2019170060 A1 WO2019170060 A1 WO 2019170060A1
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V40/00—Recognition of biometric, human-related or animal-related patterns in image or video data
- G06V40/60—Static or dynamic means for assisting the user to position a body part for biometric acquisition
- G06V40/67—Static or dynamic means for assisting the user to position a body part for biometric acquisition by interactive indications to the user
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/30—Authentication, i.e. establishing the identity or authorisation of security principals
- G06F21/31—User authentication
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
- G06F18/214—Generating training patterns; Bootstrap methods, e.g. bagging or boosting
- G06F18/2155—Generating training patterns; Bootstrap methods, e.g. bagging or boosting characterised by the incorporation of unlabelled data, e.g. multiple instance learning [MIL], semi-supervised techniques using expectation-maximisation [EM] or naïve labelling
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/40—Software arrangements specially adapted for pattern recognition, e.g. user interfaces or toolboxes therefor
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity
- G06F21/10—Protecting distributed programs or content, e.g. vending or licensing of copyrighted material ; Digital rights management [DRM]
- G06F21/16—Program or content traceability, e.g. by watermarking
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/60—Analysis of geometric attributes
- G06T7/66—Analysis of geometric attributes of image moments or centre of gravity
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/70—Labelling scene content, e.g. deriving syntactic or semantic representations
Definitions
- the present application relates to the field of medical imaging technology, and more particularly to a medical image annotation method, apparatus, user terminal and computer readable storage medium based on image authentication.
- Medical imaging refers to the technology and process of obtaining internal tissue images in a non-invasive manner for the human body or a part of the human body for medical or medical research.
- the skull edge needs to be accurately labeled to calculate the head diameter, which is used to determine whether it is well developed, and whether it is delivered or cesarean section.
- the doctor needs to use the mouse to manually circle all relevant organs (tumors) in layers in the 3D image.
- Image annotation plays a key role in precision medicine, and all image-based measurements and decisions need to be based on accurate image annotation.
- the existing method for labeling medical image images mainly requires a professional doctor to work on a medical image of a patient for several hours, which is long and inefficient, and the medical image is labeled by artificial intelligence technology.
- the hardware requirements are high and the accuracy is significantly lower than the manual labeling of the professional doctor.
- the existing methods for labeling medical image images have long time, low efficiency, high labeling cost, and low accuracy through automatic identification of artificial intelligence, which brings about the demand for labeling clinically large number of medical image images by professional doctors. Huge inconvenience.
- the present application provides a medical image annotation method, apparatus, user terminal, and computer readable storage medium based on image authentication to solve the deficiencies of the prior art.
- the present application provides a medical image annotation method based on image authentication, including:
- the annotation information of the unlabeled medical image image is obtained by the user on the login interface according to the labeled content of the unlabeled medical image image according to the labeled medical image image.
- the labeled medical image image comprises a labeled medical image image for teaching and a medical image image of known labeled data;
- the method further includes:
- the target labeling content is authenticated and stored, so that the user can obtain the unlabeled medical image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user at the login interface.
- the annotation information of the image is
- the method before acquiring the verification annotation content input by the user to the medical data image of the known annotation data, and the labeling content of the target of the unlabeled medical image image, the method further includes:
- the method further includes:
- the authentication failure is prompted, and returning to “acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as the authentication condition.
- the steps in the login screen are prompted, and returning to “acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as the authentication condition.
- the “acquiring the labeled medical image image and the unlabeled medical image image in the medical image library, and displaying the labeled medical image image and the unlabeled medical image image as the authentication condition on the login interface” includes :
- the plane positioning information of the center of gravity corresponding to the preset to-be-marked area in any labeled medical image is obtained according to the preset to-be-marked area;
- the labeled medical image image and the unlabeled medical image image are displayed as authentication conditions on the registration interface.
- the plane positioning information comprises any one of the following: a spatial coordinate in the three-dimensional image, a transverse plane horizontal to a certain vertical axis in the three-dimensional image, and a certain range of a certain center of gravity of the two-dimensional plane.
- the “using the user to obtain the annotation information of the unlabeled medical image image according to the target annotation content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface” includes:
- the target labeling content with the highest similarity is selected as the annotation information of the unlabeled medical image image.
- the user uses the target labeling content of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image according to the labeled medical image image by the user in the login interface, :
- the method before the “acquiring the labeled medical image image and the unlabeled medical image image in the medical image library”, the method further includes:
- the medical image library comprises: a first medical image sub-library and a second medical image sub-library;
- the labeled medical image image is obtained from the first medical image sub-library, and the unlabeled medical image image is obtained in the second medical image sub-library as the authentication for the user to log in to the website or other platform.
- Conditions are displayed on the login screen.
- the target annotation content may include at least one of the following: a planar annotation area of the planar image, coordinate information, relative position data, and range data
- the annotation information of the unlabeled medical image image may include at least one of the following: three-dimensional Data, spatial location information, spatial volume information, spatial relative location data.
- the present application further provides a medical image annotation device based on image authentication, comprising: an acquisition module and an annotation module;
- the acquiring module is configured to acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface;
- the labeling module is configured to acquire the labeling information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface.
- the present application further provides a user terminal, including a memory and a processor, the memory configured to be based on an image authentication medical image annotation program, the processor running the image authentication based medical image annotation The program is to cause the user terminal to perform a medical image annotation method based on image authentication as described above.
- the user terminal is a mobile terminal device having a display function
- the user terminal comprises: a processor, a network interface, a user interface, a memory, and a communication bus.
- the present application further provides a computer readable storage medium on which a medical image annotation program based on image authentication is stored, and the medical image annotation program based on image authentication is processed.
- the image recognition method based on image authentication as described above is implemented when the device is executed.
- the invention provides a medical image annotation method, device, user terminal and computer readable storage medium based on image authentication.
- the method provided by the present application displays the labeled medical image image and the unlabeled medical image image on the login interface, and uses the user to mark the content of the unlabeled medical image image, thereby obtaining the annotation information of the unlabeled medical image image.
- the online authentication method is implemented to realize large-scale collaboration of all login users, and then the medical image images are marked.
- FIG. 1 is a schematic structural diagram of a hardware operating environment involved in an embodiment of a method for marking medical images based on image authentication according to an embodiment of the present invention
- FIG. 2 is a schematic flow chart of a first embodiment of a medical image annotation method based on image authentication according to the present application
- FIG. 3 is a schematic flow chart of a second embodiment of a medical image annotation method based on image authentication according to the present application
- FIG. 4 is a schematic flow chart of a third embodiment of a medical image annotation method based on image authentication according to the present application.
- FIG. 5 is a schematic flowchart diagram of a fourth embodiment of a medical image annotation method based on image authentication according to the present application.
- FIG. 6 is a schematic flowchart of a fifth embodiment of a medical image annotation method based on image authentication according to the present application.
- FIG. 7 is a schematic diagram of functional modules of the medical image annotation device of the present application.
- first and second are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated.
- features defining “first” and “second” may include one or more of the features either explicitly or implicitly.
- the meaning of "a plurality” is two or more unless specifically and specifically defined otherwise.
- the terms “installation”, “connected”, “connected”, “fixed” and the like shall be understood broadly, and may be either a fixed connection or a detachable connection, unless otherwise explicitly stated and defined. , or integrated; can be mechanical connection, or can be electrical connection; can be directly connected, or can be indirectly connected through an intermediate medium, can be the internal communication of two elements or the interaction of two elements.
- installation can be understood on a case-by-case basis.
- FIG. 1 is a schematic structural diagram of a hardware operating environment of a user terminal according to an embodiment of the present application.
- the user terminal in the embodiment of the present application may be a PC, or may be a mobile terminal device having a display function, such as a smart phone, a tablet computer, an e-book reader, an MP3 player, an MP4 player, a portable computer, or the like.
- the user terminal may include a processor 1001, such as a CPU (Central Processing Unit), a network interface 1004, a user interface 1003, a memory 1005, and a communication bus 1002.
- the communication bus 1002 is configured to implement connection communication between these components.
- the user interface 1003 can include a display screen, an input unit such as a keyboard, a remote controller, and the optional user interface 1003 can also include a standard wired interface, a wireless interface.
- the network interface 1004 can optionally include a standard wired interface, a wireless interface (such as a WI-FI interface).
- the memory 1005 may be a high speed RAM (Random Access Memory) memory or a stable memory such as a disk memory.
- the memory 1005 can also optionally be a storage device independent of the aforementioned processor 1001.
- the processor 1001 is configured to perform the processing steps of the following modules:
- Obtaining a module acquiring the labeled medical image image and the unlabeled medical image image in the medical image library, and displaying the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface;
- the labeling module acquires the labeling information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface.
- the user terminal may further include a camera, an RF (Radio Frequency) circuit, a sensor, an audio circuit, a WiFi module, and the like.
- the mobile terminal can also be configured with other sensors such as a gyroscope, a barometer, a hygrometer, a thermometer, an infrared sensor, and the like, and details are not described herein again.
- the user terminal shown in FIG. 1 does not constitute a limitation to the terminal, and may include more or less components than those illustrated, or combine some components, or different component arrangements.
- a memory 1005 as a computer readable storage medium may include an operating system, a data interface control program, a network connection program, and a medical image tagging program based on image authentication.
- the invention provides a medical image annotation method, device and user terminal based on image authentication.
- the method enables the user to perform not only on-line authentication but also the labeling work for a large number of medical images while performing login authentication, thereby obtaining a large number of labeled medical image libraries, marking time periods and high efficiency.
- the labeling of medical images is carried out by the authentication process of each logged-in user, which greatly reduces the cost of labeling, and the manual labeling improves the accuracy of labeling, which brings great convenience for professional doctors to label the clinical medical image images. .
- a first embodiment of the present application provides a medical image annotation method based on image authentication, including:
- Step S100 Obtain an labeled medical image image and an unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface.
- the medical image library is an image library containing a large number of medical images of the same series or the same lesion, and may include, for example, angiography, computed tomography, mammography, positron emission tomography, magnetic resonance imaging, and ultrasound examination.
- the image may be a two-dimensional planar image or a three-dimensional stereoscopic visible image.
- the medical image library may include an annotated medical image sub-library (ie, a first medical image sub-library) and an unlabeled medical image sub-library (ie, a second medical image sub-library), wherein the labeled medical image sub-library includes Medical image images have been marked, and unlabeled medical image sub-libraries contain unlabeled medical image images.
- annotated medical image sub-library ie, a first medical image sub-library
- an unlabeled medical image sub-library ie, a second medical image sub-library
- the labeled medical image image is obtained from the medical image sub-library, and the unlabeled medical image image is obtained in the unlabeled medical image sub-library as the authentication condition for the user to log in to the website or other platform. , displayed on the login screen.
- the login interface may be a login interface in the website, or may be a login interface of different clients or APPs.
- Step S200 The user uses the target labeling content of the unlabeled medical image image according to the labeled medical image image on the login interface to obtain the annotation information of the unlabeled medical image image.
- the medical image image has been marked as a labeling prompt for the user's learning and whether the labeling of the user is accurate, thereby realizing the labeling of the unlabeled medical image image, obtaining the target labeling content, and then obtaining the content by the target labeling content. Label the annotation information of the medical image.
- the target labeling content may include, but is not limited to, a plane labeling area of the plane image, coordinate information, relative position data, range data, and the like.
- the labeling information of the unlabeled medical image image may include, but is not limited to, three-dimensional data, spatial position information, Information on spatial volume information, spatial relative position data, and the like.
- the method provided in this embodiment displays the labeled medical image and the unlabeled medical image on the login interface, and uses the user to mark the content of the unlabeled medical image, thereby obtaining the annotation information of the unlabeled medical image.
- the online authentication method is used to realize the large-scale collaboration of all login users, and then the medical image images are marked. Enable users to perform login authentication, not only to perform online authentication, but also to achieve a large number of medical image annotation work, thereby obtaining a large number of labeled medical image libraries, marking time period, high efficiency, through each login user
- the certification process carries out the labeling of medical images, which greatly reduces the cost of labeling, and improves the labeling accuracy rate by manual labeling, which brings great convenience for professional doctors to label the clinical medical image.
- a second embodiment of the present application provides a medical image annotation method based on image authentication.
- the labeled medical image includes a labeled medical image and a medical image. It is known to label data medical image images;
- the step S200 before the user obtains the annotation information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user, further includes:
- Step S300 acquiring verification annotation content input by the user to the medical data image of the known annotation data, and labeling content of the target of the unlabeled medical image image;
- the massive image authentication technology adopted in this embodiment is the reCAPTCHA system. It is understood that CMU (Carnegie Mellon University) designed a powerful system called reCAPTCHA to let their computers go to humans for help.
- the specific method is: the text scan image that is not recognized by the OCR software is transmitted to the major websites of the world to replace the original verification code picture; after the users of those websites correctly recognize the text, the answer will be transmitted back to the CMU.
- the labeled medical image image includes a labeled medical image image for teaching and a medical image image of known labeled data. That is, in the medical image library, two known medical image images of known labeled data are found, one of which serves as a labeled medical image image for teaching and the other as a medical image image of known labeled data.
- the hippocampus structure image includes 100 medical image images of known annotation data, wherein each hippocampus structure is marked. There are also 9900 three-dimensional brain images in which the hippocampus is not marked.
- Step S400 determining whether the similarity between the verification annotation content input by the user and the known annotation data input by the user according to the labeled medical image image for teaching reaches a preset similarity
- the method before acquiring the verification annotation content input by the user to the medical data image of the known annotation data, and the labeling content of the target of the unlabeled medical image image, the method further includes the following steps:
- the system in the process of performing authentication, that is, the process in which the user needs to log in, provides two labeled medical image images, and prompts the user to perform circle painting positioning, one of which is used as a medical medical image for teaching, and the other as Know the data of the medical image.
- the teaching uses the labeled medical image to display the marked content, while the other known labeled medical image does not display the known labeled data; the user does not display the marked according to the labeled medical image.
- Step S500 if yes, authenticating and storing the target annotation content, so as to obtain the target by using the user to mark the target of the unlabeled medical image image according to the labeled medical image image by the user on the login interface. Label the annotation information of the medical image.
- the similarity reaches the preset similarity, the user is judged to be a manual operation, a non-program operation, and the third sub-image of the user circle is the target annotation content of the unlabeled medical image image.
- Step S600 if not, prompting the authentication failure, and returning to “acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and use the labeled medical image image and the unlabeled medical image image as The authentication conditions are displayed on the login screen.
- the system will re-send the medical image image to the user for re-authentication until the authentication succeeds or a certain number of failures is reached.
- a third embodiment of the present application provides a medical image annotation method based on image authentication.
- the step S100 “acquires the labeled medical image image in the medical image library. And displaying the medical image image and displaying the labeled medical image image and the unlabeled medical image image as authentication conditions on the login interface” includes:
- Step S110 in the medical image library, acquiring, according to the preset to-be-marked area, plane positioning information of a center of gravity corresponding to the area to be marked in any of the labeled medical images;
- the plane positioning information of the center of gravity needs to be acquired according to the preset area to be marked, and the plane positioning information may be a space coordinate in the three-dimensional image, or may be a vertical direction in the three-dimensional image.
- the medical image is a three-dimensional medical image.
- the area to be marked is a medical image of the hippocampus, and the center of gravity of the hippocampus is automatically selected, and then a random plane passing through the center of gravity is generated.
- Step S120 performing a screenshot on the marked medical image and the unmarked medical image according to the plane positioning information, to obtain the labeled medical image image and the unlabeled medical image image;
- step S130 the labeled medical image image and the unlabeled medical image image are displayed as an authentication condition on the login interface.
- the marked and unmarked medical images are screenshotd according to the plane positioning information, thereby obtaining the labeled medical image image and the unlabeled medical image image.
- the client sends a verification request, randomly select two images from the 100 marked (verified by the imaging doctor) images, calling them A and B.
- One of the 9900 unlabeled images is randomly selected, called C.
- a and B because the hippocampus has been marked, we take the center of gravity of the hippocampus. Then, a random plane passing through this center of gravity is generated, and three three-dimensional images A, B, and C are intercepted by this plane.
- the two-dimensional section of the hippocampus can be obtained by intercepting the three-dimensional annotation of A and B, and then the labeled medical image and the unlabeled medical image are used as authentication conditions to authenticate the user.
- a fourth embodiment of the present application provides a medical image annotation method based on image authentication.
- the step S200 “uses the user according to the login interface according to the Labeling the medical image image with the target labeling content of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image includes:
- Step S210 acquiring the similarity of each target label content corresponding to the unlabeled medical image image
- Step S220 selecting the target labeling content with the highest similarity as the labeling information of the unlabeled medical image image.
- the system can send cross sections of the same or similar positions.
- multiple target annotation contents of the same or similar positions are obtained, and then the weight of the content is marked according to the similarity as the selection target, that is, the more accurate the user is not labeled with the medical image image, he
- the decision-making power of the circled painting result without the medical image image is greater than those of the user who does not have the high accuracy of the unlabeled medical image image (the user with low accuracy may reach the standard of the preset similarity).
- a fifth embodiment of the present application provides a medical image annotation method based on image authentication.
- the step S200 “uses the user according to the login interface according to the After the labeling the medical image image to the target labeling of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image, the method further includes:
- Step S700 Obtain the labeling information of multiple different planes corresponding to the preset to-be-marked area
- Step S800 synthesizing the annotation information of the plurality of different planes corresponding to the preset to-be-marked area, and obtaining three-dimensional annotation data corresponding to the preset to-be-marked area.
- the preset area of the three-dimensional image such as the hippocampus area
- the system can issue different sections of the area to be marked.
- the boundaries of different users in different sections of the circle, such as the boundary of the hippocampus, will be merged into a three-dimensional annotation in the background of the system.
- the method further includes:
- Step S900 receiving the verification request of the user, so as to obtain the labeled medical image image and the unlabeled medical image image in the medical image library according to the user request.
- an authentication request is made through the website, thereby performing an operation of further acquiring the labeled medical image and the unlabeled medical image in the medical image library according to the verification request.
- the present application further provides a medical image annotation device based on image authentication, comprising: an acquisition module 10 and an annotation module 20;
- the acquiring module 10 is configured to acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface. ;
- the labeling module 20 is configured to acquire the labeling information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface.
- the present application further provides a user terminal, including a memory and a processor, the memory configured to be based on an image authentication medical image annotation program, the processor running the image authentication based medical image annotation program to enable the The user terminal performs a medical image annotation method based on image authentication as described above.
- the present application further provides a computer readable storage medium, where the computer image readable storage medium stores a medical image annotation program based on image authentication, and the image authentication based medical image annotation program is implemented by a processor, such as The medical image annotation method based on image authentication described above.
- the technical solution of the present application which is essential or contributes to the prior art, may be embodied in the form of a software product stored in a storage medium (such as ROM/RAM as described above). , a disk, an optical disk, including a number of instructions for causing a terminal device (which may be a mobile phone, a computer, a server, or a network device, etc.) to perform the methods described in the various embodiments of the present application.
- a terminal device which may be a mobile phone, a computer, a server, or a network device, etc.
- the image authentication method, the device, the user terminal, and the computer readable storage medium are provided by the embodiment of the present application.
- the method provided in this embodiment enables the user to perform not only online authentication but also online authentication.
- For the labeling work of a large number of medical images a large number of labeled medical image libraries are obtained, which mark time periods and high efficiency, and the medical images are marked by the authentication process of each login user, which greatly reduces the labeling cost, and Manual labeling improves the accuracy of labeling, which brings great convenience for professional doctors to label the clinical medical image.
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Abstract
Description
相关申请的交叉引用Cross-reference to related applications
本申请要求于2018年03月05日提交中国专利局的优先权号为2018101805400、名称为“一种基于图像认证的医学影像标注方法、装置和用户终端”的中国专利申请的优先权,其全部内容通过引用结合在本申请中。The present application claims priority to Chinese Patent Application No. 2018101805400, entitled "Image Image-Based Medical Image Labeling Method, Apparatus and User Terminal", filed on March 5, 2018, the entire disclosure of which is hereby incorporated by reference. The content is incorporated herein by reference.
本申请涉及医学影像技术领域,更具体地说,涉及一种基于图像认证的医学影像标注方法、装置、用户终端和计算机可读存储介质。The present application relates to the field of medical imaging technology, and more particularly to a medical image annotation method, apparatus, user terminal and computer readable storage medium based on image authentication.
医学影像是指为了医疗或医学研究,对人体或人体某部分,以非侵入方式取得内部组织影像的技术与处理过程。Medical imaging refers to the technology and process of obtaining internal tissue images in a non-invasive manner for the human body or a part of the human body for medical or medical research.
在医学领域需要对大量的医学影像图像进行图像标注和测量,从而作为医学决策、下医嘱的依据。例如:胎儿图像中,需要准确标注颅骨边缘,才能计算头径,用于判断是否发育良好,以及是否顺产或剖宫产;再例如:在放射性肿瘤治疗中,为了精准确定肿瘤和周边正常器官的位置,医生需要用鼠标在三维图像中一层层的手工圈出所有相关器官(肿瘤)。In the medical field, it is necessary to image and measure a large number of medical image images, which serves as the basis for medical decision-making and medical treatment. For example, in the fetal image, the skull edge needs to be accurately labeled to calculate the head diameter, which is used to determine whether it is well developed, and whether it is delivered or cesarean section. For example, in the treatment of radiation tumors, in order to accurately determine the tumor and surrounding normal organs. Position, the doctor needs to use the mouse to manually circle all relevant organs (tumors) in layers in the 3D image.
图像标注在精准医疗中起到了基石性的作用,所有基于图像的测量和决策都需要基于准确的图像标注。现有的对于医学影像图像进行标注的方法主要通过专业医生针对某一个病人的医学影像图圈画工作长达数个小时,时间长、效率低,而通过人工智能技术对医学影像图像进行标注对硬件要求高,且准确率明显低于专业医生的人工标注。总之,现有的对于医学影像图像进行标注的方法具有时间长、效率低、标注成本高,且通过人工智能自动识别的准确率低,为专业医生对于临床大量医学影像图像的标注需求带来了巨大的不便。Image annotation plays a key role in precision medicine, and all image-based measurements and decisions need to be based on accurate image annotation. The existing method for labeling medical image images mainly requires a professional doctor to work on a medical image of a patient for several hours, which is long and inefficient, and the medical image is labeled by artificial intelligence technology. The hardware requirements are high and the accuracy is significantly lower than the manual labeling of the professional doctor. In short, the existing methods for labeling medical image images have long time, low efficiency, high labeling cost, and low accuracy through automatic identification of artificial intelligence, which brings about the demand for labeling clinically large number of medical image images by professional doctors. Huge inconvenience.
发明内容Summary of the invention
有鉴于此,本申请提供一种基于图像认证的医学影像标注方法、装置、用户终端和计算机可读存储介质以解决现有技术的不足。In view of this, the present application provides a medical image annotation method, apparatus, user terminal, and computer readable storage medium based on image authentication to solve the deficiencies of the prior art.
为解决上述问题,本申请提供一种基于图像认证的医学影像标注方法,包括:To solve the above problem, the present application provides a medical image annotation method based on image authentication, including:
获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面;Obtaining the labeled medical image image and the unlabeled medical image image in the medical image library, and displaying the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface;
利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。The annotation information of the unlabeled medical image image is obtained by the user on the login interface according to the labeled content of the unlabeled medical image image according to the labeled medical image image.
优选地,所述已标注医学影像图像包括教学用已标医学影像图像和已知标注数据医学 影像图像;Preferably, the labeled medical image image comprises a labeled medical image image for teaching and a medical image image of known labeled data;
所述“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”之前,还包括:Before the user obtains the annotation information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user in the login interface, the method further includes:
获取所述用户对所述已知标注数据医学影像图像输入的验证标注内容,以及对所述未标注医学影像图像的目标标注内容,其中,所述验证标注内容为所述用户根据所述教学用已标医学影像图像对所述已知标注数据医学影像图像输入的验证标注内容;Obtaining the verification annotation content input by the user on the medical data image of the known annotation data, and the target annotation content of the unlabeled medical image image, wherein the verification annotation content is used by the user according to the teaching Verification of the labeled content of the medical image image input by the labeled medical image;
判断所述用户根据所述教学用已标医学影像图像对所述已知标注数据医学影像图像输入的所述验证标注内容与已知标注数据的相似度是否达到预设相似度;Determining whether the similarity between the verified annotation content input by the user and the known annotation data according to the labeled medical image image of the teaching to the known annotation data reaches a preset similarity;
若是,则通过认证并存储所述目标标注内容,以便于利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。If yes, the target labeling content is authenticated and stored, so that the user can obtain the unlabeled medical image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user at the login interface. The annotation information of the image.
优选地,在获取所述用户对所述已知标注数据医学影像图像输入的验证标注内容,以及对所述未标注医学影像图像的目标标注内容之前,所述方法还包括:Preferably, before acquiring the verification annotation content input by the user to the medical data image of the known annotation data, and the labeling content of the target of the unlabeled medical image image, the method further includes:
确定所述教学用已标医学影像图像和所述已知标注数据医学影像图像,其中,所述教学用已标医学影像图像中显示出标记内容,所述已知标注数据医学影像图像不显示已知标注数据;Determining the labeled medical image image for teaching and the medical image image of the known annotation data, wherein the teaching content is displayed in the labeled medical image image, and the known annotation data medical image image is not displayed Know the data of the annotation;
根据所述教学用已标医学影像图像对不显示标记的所述已知标注数据医学影像图像进行标记,并对所述未标注医学影像图像进行标记,从而得到所述用户的对于所述已知标注数据医学影像图像的标记内容和对于所述未标注医学影像图像的目标标注内容。Marking the known annotation data medical image image that does not display the mark according to the teaching medical target image, and marking the unlabeled medical image image, thereby obtaining the known Marking content of the data medical image image and target labeling content for the unlabeled medical image image.
优选地,所述“判断所述已知标注数据医学影像图像输入的所述验证标注内容的相似度是否达到预设相似度”之后,还包括:Preferably, after the “determining whether the similarity of the verified annotation content of the known annotation data medical image image input reaches a preset similarity”, the method further includes:
若否,则提示认证失败,并返回“获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面”的步骤。If not, the authentication failure is prompted, and returning to “acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as the authentication condition. The steps in the login screen.
优选地,所述“获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面”包括:Preferably, the “acquiring the labeled medical image image and the unlabeled medical image image in the medical image library, and displaying the labeled medical image image and the unlabeled medical image image as the authentication condition on the login interface” includes :
所述医学影像库中,根据预设待标记区域获取任意已标注的医学影像中预设待标记区域对应的重心的平面定位信息;In the medical image library, the plane positioning information of the center of gravity corresponding to the preset to-be-marked area in any labeled medical image is obtained according to the preset to-be-marked area;
根据所述平面定位信息对所述已标记的医学影像和所述未标记的医学影像进行截图,得到所述已标注医学影像图像和所述未标注医学影像图像;Performing a screenshot on the marked medical image and the unlabeled medical image according to the plane positioning information, to obtain the labeled medical image image and the unlabeled medical image image;
将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界 面。The labeled medical image image and the unlabeled medical image image are displayed as authentication conditions on the registration interface.
优选地,所述平面定位信息包括以下任一种:在三维图像中的空间坐标,三维图像中的以某一纵轴水平的横切平面,二维平面的某一重心的一定的范围。Preferably, the plane positioning information comprises any one of the following: a spatial coordinate in the three-dimensional image, a transverse plane horizontal to a certain vertical axis in the three-dimensional image, and a certain range of a certain center of gravity of the two-dimensional plane.
优选地,所述“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”包括:Preferably, the “using the user to obtain the annotation information of the unlabeled medical image image according to the target annotation content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface” includes:
获取所述未标注医学影像图像对应的每一个目标标注内容的所述相似度;Obtaining the similarity of each target label content corresponding to the unlabeled medical image image;
选择所述相似度最高的所述目标标注内容作为所述未标注医学影像图像的所述标注信息。The target labeling content with the highest similarity is selected as the annotation information of the unlabeled medical image image.
优选地,所述“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”之后,还包括:Preferably, after the user uses the target labeling content of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image according to the labeled medical image image by the user in the login interface, :
获取所述预设待标记区域对应的多个不同平面的所述标注信息;Obtaining the annotation information of the plurality of different planes corresponding to the preset to-be-marked area;
对所述预设待标记区域对应的多个不同平面的所述标注信息进行合成,得到与所述预设待标记区域对应的三维标注数据。And combining the annotation information of the plurality of different planes corresponding to the preset to-be-marked area to obtain three-dimensional annotation data corresponding to the preset to-be-marked area.
优选地,所述“获取医学影像库中的已标注医学影像图像和未标注医学影像图像”之前,还包括:Preferably, before the “acquiring the labeled medical image image and the unlabeled medical image image in the medical image library”, the method further includes:
接收所述用户的验证请求,以便于根据所述用户请求获取医学影像库中的已标注医学影像图像和未标注医学影像图像。Receiving the verification request of the user, so as to obtain the labeled medical image image and the unlabeled medical image image in the medical image library according to the user request.
优选地,所述医学影像库包括:第一医学影像子库和第二医学影像子库;Preferably, the medical image library comprises: a first medical image sub-library and a second medical image sub-library;
获取医学影像库中的已标注医学影像图像和未标注医学影像图像包括:Obtaining the labeled medical image image and the unlabeled medical image image in the medical image library includes:
将在进行对用户的认证时,从第一医学影像子库中获取已标注医学影像图像,并在第二医学影像子库中获取未标注医学影像图像,作为对于用户登录网站或其他平台的认证条件,显示于登录界面。When the user is authenticated, the labeled medical image image is obtained from the first medical image sub-library, and the unlabeled medical image image is obtained in the second medical image sub-library as the authentication for the user to log in to the website or other platform. Conditions are displayed on the login screen.
优选地,所述目标标注内容可以包括以下至少之一:平面图像的平面标注区域、坐标信息、相对位置数据、范围数据,所述未标注医学影像图像的标注信息可以包括以下至少之一:三维数据、空间位置信息、空间体积信息、空间相对位置数据。Preferably, the target annotation content may include at least one of the following: a planar annotation area of the planar image, coordinate information, relative position data, and range data, and the annotation information of the unlabeled medical image image may include at least one of the following: three-dimensional Data, spatial location information, spatial volume information, spatial relative location data.
此外,为解决上述问题,本申请还提供一种基于图像认证的医学影像标注装置,包括:获取模块和标注模块;In addition, in order to solve the above problem, the present application further provides a medical image annotation device based on image authentication, comprising: an acquisition module and an annotation module;
所述获取模块,配置成获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面;The acquiring module is configured to acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface;
所述标注模块,配置成利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。The labeling module is configured to acquire the labeling information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface.
此外,为解决上述问题,本申请还提供一种用户终端,包括存储器以及处理器,所述存储器配置成基于图像认证的医学影像标注程序,所述处理器运行所述基于图像认证的医学影像标注程序以使所述用户终端执行如上述所述基于图像认证的医学影像标注方法。In addition, in order to solve the above problems, the present application further provides a user terminal, including a memory and a processor, the memory configured to be based on an image authentication medical image annotation program, the processor running the image authentication based medical image annotation The program is to cause the user terminal to perform a medical image annotation method based on image authentication as described above.
优选地,所述用户终端为具有显示功能的可移动式终端设备,所述用户终端包括:处理器,网络接口,用户接口,存储器,通信总线。Preferably, the user terminal is a mobile terminal device having a display function, and the user terminal comprises: a processor, a network interface, a user interface, a memory, and a communication bus.
此外,为解决上述问题,本申请还提供一种计算机可读存储介质,所述计算机可读存储介质上存储有基于图像认证的医学影像标注程序,所述基于图像认证的医学影像标注程序被处理器执行时实现如上述所述基于图像认证的医学影像标注方法。In addition, in order to solve the above problems, the present application further provides a computer readable storage medium on which a medical image annotation program based on image authentication is stored, and the medical image annotation program based on image authentication is processed. The image recognition method based on image authentication as described above is implemented when the device is executed.
本申请提供的一种基于图像认证的医学影像标注方法、装置、用户终端和计算机可读存储介质。其中,本申请所提供的方法通过在登录界面显示已标注医学影像图像和未标注医学影像图像,并利用用户对于未标注医学影像图像的标注内容,从而获取到未标注医学影像图像的标注信息,从而实现了通过在线认证的方法实现所有登录用户大规模协作,进而对医学影像图像进行标注。使用户在进行登录认证的同时,实现不仅进行在线认证,又可以实现对于海量的医学图像的标注工作,从而得到海量的有标注的医学图像库,标注时间段、效率高,通过每个登录用户的认证过程进行对医学影像的标注,大大降低了标注成本,且由于人工标注,提高了标注准确率,为专业医生对于临床大量医学影像图像的标注需求带来了巨大的方便。The invention provides a medical image annotation method, device, user terminal and computer readable storage medium based on image authentication. The method provided by the present application displays the labeled medical image image and the unlabeled medical image image on the login interface, and uses the user to mark the content of the unlabeled medical image image, thereby obtaining the annotation information of the unlabeled medical image image. Thereby, the online authentication method is implemented to realize large-scale collaboration of all login users, and then the medical image images are marked. Enable users to perform login authentication, not only to perform online authentication, but also to achieve a large number of medical image annotation work, thereby obtaining a large number of labeled medical image libraries, marking time period, high efficiency, through each login user The certification process carries out the labeling of medical images, which greatly reduces the cost of labeling, and improves the labeling accuracy rate by manual labeling, which brings great convenience for professional doctors to label the clinical medical image.
为了更清楚地说明本申请实施例的技术方案,下面将对实施例中所需要使用的附图作简单地介绍,应当理解,以下附图仅示出了本申请的某些实施例,因此不应被看作是对范围的限定,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他相关的附图。In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings to be used in the embodiments will be briefly described below. It should be understood that the following drawings show only certain embodiments of the present application, and therefore It should be seen as a limitation on the scope, and those skilled in the art can obtain other related drawings according to these drawings without any creative work.
图1为本申请基于图像认证的医学影像标注方法实施例方案涉及的硬件运行环境的结构示意图;1 is a schematic structural diagram of a hardware operating environment involved in an embodiment of a method for marking medical images based on image authentication according to an embodiment of the present invention;
图2为本申请基于图像认证的医学影像标注方法第一实施例的流程示意图;2 is a schematic flow chart of a first embodiment of a medical image annotation method based on image authentication according to the present application;
图3为本申请基于图像认证的医学影像标注方法第二实施例的流程示意图;3 is a schematic flow chart of a second embodiment of a medical image annotation method based on image authentication according to the present application;
图4为本申请基于图像认证的医学影像标注方法第三实施例的流程示意图;4 is a schematic flow chart of a third embodiment of a medical image annotation method based on image authentication according to the present application;
图5为本申请基于图像认证的医学影像标注方法第四实施例的流程示意图;FIG. 5 is a schematic flowchart diagram of a fourth embodiment of a medical image annotation method based on image authentication according to the present application; FIG.
图6为本申请基于图像认证的医学影像标注方法第五实施例的流程示意图;6 is a schematic flowchart of a fifth embodiment of a medical image annotation method based on image authentication according to the present application;
图7为本申请医学影像标注装置的功能模块示意图。FIG. 7 is a schematic diagram of functional modules of the medical image annotation device of the present application.
本申请目的的实现、功能特点及优点将结合实施例,参照附图做进一步说明。The implementation, functional features and advantages of the present application will be further described with reference to the accompanying drawings.
下面详细描述本申请的实施例,其中自始至终相同或类似的标号表示相同或类似的元件或具有相同或类似功能的元件。The embodiments of the present application are described in detail below, wherein the same or similar reference numerals indicate the same or similar elements or elements having the same or similar functions.
此外,术语“第一”、“第二”仅用于描述目的,而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此,限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个该特征。在本申请的描述中,“多个”的含义是两个或两个以上,除非另有明确具体的限定。Moreover, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, features defining "first" and "second" may include one or more of the features either explicitly or implicitly. In the description of the present application, the meaning of "a plurality" is two or more unless specifically and specifically defined otherwise.
在本申请中,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”、“固定”等术语应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或成一体;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通或两个元件的相互作用关系。对于本领域的普通技术人员而言,可以根据具体情况理解上述术语在本申请中的具体含义。In the present application, the terms "installation", "connected", "connected", "fixed" and the like shall be understood broadly, and may be either a fixed connection or a detachable connection, unless otherwise explicitly stated and defined. , or integrated; can be mechanical connection, or can be electrical connection; can be directly connected, or can be indirectly connected through an intermediate medium, can be the internal communication of two elements or the interaction of two elements. For those skilled in the art, the specific meanings of the above terms in the present application can be understood on a case-by-case basis.
应当理解,此处所描述的具体实施例仅仅用以解释本申请,并不用于限定本申请。It is understood that the specific embodiments described herein are merely illustrative of the application and are not intended to be limiting.
如图1所示,图1是本申请实施例方案涉及的用户终端的硬件运行环境的结构示意图。As shown in FIG. 1 , FIG. 1 is a schematic structural diagram of a hardware operating environment of a user terminal according to an embodiment of the present application.
本申请实施例用户终端可以是PC,也可以是智能手机、平板电脑、电子书阅读器、MP3播放器、MP4播放器、便携计算机等具有显示功能的可移动式终端设备。The user terminal in the embodiment of the present application may be a PC, or may be a mobile terminal device having a display function, such as a smart phone, a tablet computer, an e-book reader, an MP3 player, an MP4 player, a portable computer, or the like.
如图1所示,该用户终端可以包括:处理器1001,例如CPU(Central Processing Unit,中央处理器),网络接口1004,用户接口1003,存储器1005,通信总线1002。其中,通信总线1002配置成实现这些组件之间的连接通信。用户接口1003可以包括显示屏、输入单元比如键盘、遥控器,可选用户接口1003还可以包括标准的有线接口、无线接口。网络接口1004可选的可以包括标准的有线接口、无线接口(如WI-FI接口)。存储器1005可以是高速RAM(Random Access Memory,随机存取存储器)存储器,也可以是稳定的存储器,例如磁盘存储器。存储器1005可选的还可以是独立于前述处理器1001的存储装置。As shown in FIG. 1, the user terminal may include a
在本实施例中,处理器1001配置成执行以下模块的处理步骤:In this embodiment, the
获取模块,获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面;Obtaining a module, acquiring the labeled medical image image and the unlabeled medical image image in the medical image library, and displaying the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface;
标注模块,利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。The labeling module acquires the labeling information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user on the login interface.
可选地,用户终端还可以包括摄像头、RF(Radio Frequency,射频)电路,传感器、音频电路、WiFi模块等等。此外,移动终端还可配置陀螺仪、气压计、湿度计、温度计、 红外线传感器等其他传感器,在此不再赘述。Optionally, the user terminal may further include a camera, an RF (Radio Frequency) circuit, a sensor, an audio circuit, a WiFi module, and the like. In addition, the mobile terminal can also be configured with other sensors such as a gyroscope, a barometer, a hygrometer, a thermometer, an infrared sensor, and the like, and details are not described herein again.
本领域技术人员可以理解,图1中示出的用户终端并不构成对终端的限定,可以包括比图示更多或更少的部件,或者组合某些部件,或者不同的部件布置。It will be understood by those skilled in the art that the user terminal shown in FIG. 1 does not constitute a limitation to the terminal, and may include more or less components than those illustrated, or combine some components, or different component arrangements.
如图1所示,作为一种计算机可读存储介质的存储器1005中可以包括操作系统、数据接口控制程序、网络连接程序以及基于图像认证的医学影像标注程序。As shown in FIG. 1, a
本申请提供的一种基于图像认证的医学影像标注方法、装置和用户终端。其中,所述方法使用户在进行登录认证的同时,实现不仅进行在线认证,又可以实现对于海量的医学图像的标注工作,从而得到海量的有标注的医学图像库,标注时间段、效率高,通过每个登录用户的认证过程进行对医学影像的标注,大大降低了标注成本,且由于人工标注,提高了标注准确率,为专业医生对于临床大量医学影像图像的标注需求带来了巨大的方便。The invention provides a medical image annotation method, device and user terminal based on image authentication. The method enables the user to perform not only on-line authentication but also the labeling work for a large number of medical images while performing login authentication, thereby obtaining a large number of labeled medical image libraries, marking time periods and high efficiency. The labeling of medical images is carried out by the authentication process of each logged-in user, which greatly reduces the cost of labeling, and the manual labeling improves the accuracy of labeling, which brings great convenience for professional doctors to label the clinical medical image images. .
实施例1:Example 1:
参照图2,本申请第一实施例提供一种基于图像认证的医学影像标注方法,包括:Referring to FIG. 2, a first embodiment of the present application provides a medical image annotation method based on image authentication, including:
步骤S100,获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面。Step S100: Obtain an labeled medical image image and an unlabeled medical image image in the medical image library, and display the labeled medical image image and the unlabeled medical image image as an authentication condition on the login interface.
上述,医学影像库,为包含有大量同系列同类别或同病灶的医学影像的图像库,例如,可以包括血管摄影、电脑断层扫描、乳房摄影、正电子发射断层扫描、核磁共振成像、超声波检查等数据结果,其图像可以为二维平面图像,也可以为三维的立体可视图像。In the above, the medical image library is an image library containing a large number of medical images of the same series or the same lesion, and may include, for example, angiography, computed tomography, mammography, positron emission tomography, magnetic resonance imaging, and ultrasound examination. As a result of the data, the image may be a two-dimensional planar image or a three-dimensional stereoscopic visible image.
医学影像库可以包括已标注医学影像子库(即,第一医学影像子库)和未标注医学影像子库(即,第二医学影像子库),其中,已标注医学影像子库中包含有已标注医学影像图像,未标注医学影像子库中包含有未标注医学影像图像。The medical image library may include an annotated medical image sub-library (ie, a first medical image sub-library) and an unlabeled medical image sub-library (ie, a second medical image sub-library), wherein the labeled medical image sub-library includes Medical image images have been marked, and unlabeled medical image sub-libraries contain unlabeled medical image images.
上述,将在进行对用户的认证时,从医学影像子库中获取已标注医学影像图像,在未标注医学影像子库中获取未标注医学影像图像,作为对于用户登录网站或其他平台的认证条件,显示于登录界面。In the above, when the user is authenticated, the labeled medical image image is obtained from the medical image sub-library, and the unlabeled medical image image is obtained in the unlabeled medical image sub-library as the authentication condition for the user to log in to the website or other platform. , displayed on the login screen.
上述,登录界面可以为网站中的登录界面,也可以为不同客户端或APP的登录界面。In the above, the login interface may be a login interface in the website, or may be a login interface of different clients or APPs.
步骤S200,利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。Step S200: The user uses the target labeling content of the unlabeled medical image image according to the labeled medical image image on the login interface to obtain the annotation information of the unlabeled medical image image.
上述,已标注医学影像图像可以作为对用户的学习用的标注提示以及对于用户的标注是否准确的判断,从而实现未标注医学影像图像的标注,得到目标标注内容,进而通过目标标注内容,获取未标注医学影像图像的标注信息。In the above, the medical image image has been marked as a labeling prompt for the user's learning and whether the labeling of the user is accurate, thereby realizing the labeling of the unlabeled medical image image, obtaining the target labeling content, and then obtaining the content by the target labeling content. Label the annotation information of the medical image.
上述,目标标注内容可以包括但不限于平面图像的平面标注区域、坐标信息、相对位置数据、范围数据等等信息,未标注医学影像图像的标注信息可以包括但不限于三维数据、 空间位置信息、空间体积信息、空间相对位置数据等等信息。The target labeling content may include, but is not limited to, a plane labeling area of the plane image, coordinate information, relative position data, range data, and the like. The labeling information of the unlabeled medical image image may include, but is not limited to, three-dimensional data, spatial position information, Information on spatial volume information, spatial relative position data, and the like.
本实施例提供的方法通过在登录界面显示已标注医学影像图像和未标注医学影像图像,并利用用户对于未标注医学影像图像的标注内容,从而获取到未标注医学影像图像的标注信息,从而实现了通过在线认证的方法实现所有登录用户大规模协作,进而对医学影像图像进行标注。使用户在进行登录认证的同时,实现不仅进行在线认证,又可以实现对于海量的医学图像的标注工作,从而得到海量的有标注的医学图像库,标注时间段、效率高,通过每个登录用户的认证过程进行对医学影像的标注,大大降低了标注成本,且由于人工标注,提高了标注准确率,为专业医生对于临床大量医学影像图像的标注需求带来了巨大的方便。The method provided in this embodiment displays the labeled medical image and the unlabeled medical image on the login interface, and uses the user to mark the content of the unlabeled medical image, thereby obtaining the annotation information of the unlabeled medical image. The online authentication method is used to realize the large-scale collaboration of all login users, and then the medical image images are marked. Enable users to perform login authentication, not only to perform online authentication, but also to achieve a large number of medical image annotation work, thereby obtaining a large number of labeled medical image libraries, marking time period, high efficiency, through each login user The certification process carries out the labeling of medical images, which greatly reduces the cost of labeling, and improves the labeling accuracy rate by manual labeling, which brings great convenience for professional doctors to label the clinical medical image.
实施例2:Example 2:
参照图3,本申请第二实施例提供一种基于图像认证的医学影像标注方法,基于上述图2所示的第一实施例,所述已标注医学影像图像包括教学用已标医学影像图像和已知标注数据医学影像图像;Referring to FIG. 3, a second embodiment of the present application provides a medical image annotation method based on image authentication. Based on the first embodiment shown in FIG. 2, the labeled medical image includes a labeled medical image and a medical image. It is known to label data medical image images;
所述步骤S200“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”之前,还包括:The step S200, before the user obtains the annotation information of the unlabeled medical image image by using the target labeling content of the unlabeled medical image image according to the labeled medical image image by the user, further includes:
步骤S300,获取所述用户对所述已知标注数据医学影像图像输入的验证标注内容,以及对所述未标注医学影像图像的目标标注内容;Step S300, acquiring verification annotation content input by the user to the medical data image of the known annotation data, and labeling content of the target of the unlabeled medical image image;
上述,本实施例采用的海量图像认证技术为reCAPTCHA系统,需要理解的是,CMU(卡耐基梅隆大学)设计了一个名叫reCAPTCHA的强大系统,让他们的电脑去向人类求助。具体做法是:将OCR软件无法识别的文字扫描图传给世界各大网站,用以替换原来的验证码图片;那些网站的用户在正确识别出这些文字之后,其答案便会被传回CMU。In the above, the massive image authentication technology adopted in this embodiment is the reCAPTCHA system. It is understood that CMU (Carnegie Mellon University) designed a powerful system called reCAPTCHA to let their computers go to humans for help. The specific method is: the text scan image that is not recognized by the OCR software is transmitted to the major websites of the world to replace the original verification code picture; after the users of those websites correctly recognize the text, the answer will be transmitted back to the CMU.
上述,所述已标注医学影像图像包括教学用已标医学影像图像和已知标注数据医学影像图像。即为,在医学影像库中,找出两个已知的已知标注数据医学影像图像,其中一个作为教学用已标医学影像图像,另一个作为已知标注数据医学影像图像。例如,在医学影像库中,海马区结构影像包括100个已知标注数据医学影像图像,其中每个的海马区结构都被标记。还有9900个三维脑图像,其中海马区未进行标记。In the above, the labeled medical image image includes a labeled medical image image for teaching and a medical image image of known labeled data. That is, in the medical image library, two known medical image images of known labeled data are found, one of which serves as a labeled medical image image for teaching and the other as a medical image image of known labeled data. For example, in the medical image library, the hippocampus structure image includes 100 medical image images of known annotation data, wherein each hippocampus structure is marked. There are also 9900 three-dimensional brain images in which the hippocampus is not marked.
步骤S400,判断所述用户根据所述教学用已标医学影像图像对所述已知标注数据医学影像图像输入的所述验证标注内容与已知标注数据的相似度是否达到预设相似度;Step S400, determining whether the similarity between the verification annotation content input by the user and the known annotation data input by the user according to the labeled medical image image for teaching reaches a preset similarity;
上述,在客户端或用户端进行认证时,即为对不同的医学影像进行圈画,在客户端,我们采用快速的二维图像交互式分割算法,辅助用户快速的圈出他/她想圈画的区域。而不需要用户精细的拖着鼠标勾画。类比reCAPTCHA系统,整个过程可以在数秒内完成。In the above, when the client or the client authenticates, it is to circle different medical images. On the client side, we adopt a fast two-dimensional image interactive segmentation algorithm to assist the user to quickly circle his/her circle. The area of the painting. It does not require the user to drag the mouse to draw. Analogous to the reCAPTCHA system, the entire process can be completed in seconds.
可选地,在获取所述用户对所述已知标注数据医学影像图像输入的验证标注内容,以及对所述未标注医学影像图像的目标标注内容之前,所述方法还包括如下步骤:Optionally, before acquiring the verification annotation content input by the user to the medical data image of the known annotation data, and the labeling content of the target of the unlabeled medical image image, the method further includes the following steps:
确定所述教学用已标医学影像图像和所述已知标注数据医学影像图像,其中,所述教学用已标医学影像图像中显示出标记内容,所述已知标注数据医学影像图像不显示已知标注数据;以及根据所述教学用已标医学影像图像对不显示标记的所述已知标注数据医学影像图像进行标记,并对所述未标注医学影像图像进行标记,从而得到所述用户的对于所述已知标注数据医学影像图像的标记内容和对于所述未标注医学影像图像的目标标注内容。Determining the labeled medical image image for teaching and the medical image image of the known annotation data, wherein the teaching content is displayed in the labeled medical image image, and the known annotation data medical image image is not displayed Knowing the annotation data; and marking the known annotation data medical image image that does not display the mark according to the teaching medical image image, and marking the unlabeled medical image image, thereby obtaining the user's Marking content of the medical data image of the known labeled data and a content of the target for the unlabeled medical image image.
上述,在进行认证过程中,即为用户需要进行登录的过程,系统提供两个已标注医学影像图像,并提示用户进行圈画定位,其中一个作为教学用已标医学影像图像,另一个作为已知标注数据医学影像图像。教学用已标医学影像图像中显示出其中的标记内容,而另一幅的已知标注数据医学影像图像则不显示已知标注数据;用户根据教学用已标医学影像图像对不显示标记的已知标注数据医学影像图像进行标记,另外也对未标注医学影像图像进行标记,从而系统得到用户的对于已知标注数据医学影像图像的标记内容和对于未标注医学影像图像的目标标注内容,进而对已知标注数据医学影像图像的标记内容与已知标注数据的相似度是否达到预设的相似度进行判断。In the above process, in the process of performing authentication, that is, the process in which the user needs to log in, the system provides two labeled medical image images, and prompts the user to perform circle painting positioning, one of which is used as a medical medical image for teaching, and the other as Know the data of the medical image. The teaching uses the labeled medical image to display the marked content, while the other known labeled medical image does not display the known labeled data; the user does not display the marked according to the labeled medical image. Knowing the labeling data medical image image for marking, and also marking the unlabeled medical image image, so that the system obtains the user's marked content of the medical image image of the known labeled data and the target labeling content for the unlabeled medical image image, and then It is known that the similarity between the marked content of the labeled data medical image image and the known annotation data reaches a preset similarity.
步骤S500,若是,则通过认证并存储所述目标标注内容,以便于利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。Step S500, if yes, authenticating and storing the target annotation content, so as to obtain the target by using the user to mark the target of the unlabeled medical image image according to the labeled medical image image by the user on the login interface. Label the annotation information of the medical image.
上述,如果相似度达到预设的相似度,则判断用户为人工操作,非程序操作,并将用户圈画的第三副图像即为未标注医学影像图像的目标标注内容进行存储。In the above, if the similarity reaches the preset similarity, the user is judged to be a manual operation, a non-program operation, and the third sub-image of the user circle is the target annotation content of the unlabeled medical image image.
步骤S600,若否,则提示认证失败,并返回“获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面”。Step S600, if not, prompting the authentication failure, and returning to “acquire the labeled medical image image and the unlabeled medical image image in the medical image library, and use the labeled medical image image and the unlabeled medical image image as The authentication conditions are displayed on the login screen.
上述,如果相似度不符合预设相似度,则出现认证失败的情况,系统将会重新发给用户医学影像图像进行重新认证,直到认证成功或达到一定的失败次数为止。In the above, if the similarity does not meet the preset similarity, the authentication failure occurs, and the system will re-send the medical image image to the user for re-authentication until the authentication succeeds or a certain number of failures is reached.
实施例3:Example 3:
参照图4,本申请第三实施例提供一种基于图像认证的医学影像标注方法,基于上述图2所示的第一实施例,所述步骤S100“获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面”包括:Referring to FIG. 4, a third embodiment of the present application provides a medical image annotation method based on image authentication. Based on the first embodiment shown in FIG. 2, the step S100 “acquires the labeled medical image image in the medical image library. And displaying the medical image image and displaying the labeled medical image image and the unlabeled medical image image as authentication conditions on the login interface" includes:
步骤S110,所述医学影像库中,根据预设待标记区域获取任意已标注的医学影像中预 设待标记区域对应的重心的平面定位信息;Step S110, in the medical image library, acquiring, according to the preset to-be-marked area, plane positioning information of a center of gravity corresponding to the area to be marked in any of the labeled medical images;
上述,在医学影像库中,需要根据预设待标记区域进行获取其中重心的平面定位信息,所述平面定位信息可以为在三维图像中的空间坐标,也可以为三维图像中的以某一纵轴水平的横切平面,或者二维平面的某一重心的一定的范围。在本实施例中,所针对的医学影像为三维的医学影像,例如,待标记区域为海马区医学影像,自动选择其中海马区的重心,然后生成一个过此重心的随机平面。In the above, in the medical image library, the plane positioning information of the center of gravity needs to be acquired according to the preset area to be marked, and the plane positioning information may be a space coordinate in the three-dimensional image, or may be a vertical direction in the three-dimensional image. A transverse plane of the axis, or a certain range of a certain center of gravity of a two-dimensional plane. In this embodiment, the medical image is a three-dimensional medical image. For example, the area to be marked is a medical image of the hippocampus, and the center of gravity of the hippocampus is automatically selected, and then a random plane passing through the center of gravity is generated.
步骤S120,根据所述平面定位信息对所述已标记的医学影像和所述未标记的医学影像进行截图,得到所述已标注医学影像图像和所述未标注医学影像图像;Step S120, performing a screenshot on the marked medical image and the unmarked medical image according to the plane positioning information, to obtain the labeled medical image image and the unlabeled medical image image;
步骤S130,将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面。In step S130, the labeled medical image image and the unlabeled medical image image are displayed as an authentication condition on the login interface.
上述,根据平面定位信息对已标记的和未标记的医学影像进行截图,从而得到了已标注医学影像图像和所述未标注医学影像图像。例如,在当客户端发来验证请求时,随机从100个有标记(经过影像科医生验证)的图像中选取两个图像,称它们为A和B。从9900个未标注图像中随机抽取一个,称为C。在A和B中,因为海马区已经有标注,我们取海马区的重心。然后,生成一个过此重心的随机平面,用此平面截取三个三维图像A、B、和C。获得三幅二维图像a、b、c。其中a和b中,海马区的二维截面可以通过截取A和B的三维标注获得,进而将已标注医学影像图像和未标注医学影像图像作为认证条件进行对用户的登录认证。In the above, the marked and unmarked medical images are screenshotd according to the plane positioning information, thereby obtaining the labeled medical image image and the unlabeled medical image image. For example, when the client sends a verification request, randomly select two images from the 100 marked (verified by the imaging doctor) images, calling them A and B. One of the 9900 unlabeled images is randomly selected, called C. In A and B, because the hippocampus has been marked, we take the center of gravity of the hippocampus. Then, a random plane passing through this center of gravity is generated, and three three-dimensional images A, B, and C are intercepted by this plane. Obtain three two-dimensional images a, b, c. In a and b, the two-dimensional section of the hippocampus can be obtained by intercepting the three-dimensional annotation of A and B, and then the labeled medical image and the unlabeled medical image are used as authentication conditions to authenticate the user.
实施例4:Example 4:
参照图5,本申请第四实施例提供一种基于图像认证的医学影像标注方法,基于上述图3所示的第二实施例,所述步骤S200“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”包括:Referring to FIG. 5, a fourth embodiment of the present application provides a medical image annotation method based on image authentication. Based on the second embodiment shown in FIG. 3, the step S200 “uses the user according to the login interface according to the Labeling the medical image image with the target labeling content of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image includes:
步骤S210,获取所述未标注医学影像图像对应的每一个目标标注内容的所述相似度;Step S210, acquiring the similarity of each target label content corresponding to the unlabeled medical image image;
步骤S220,选择所述相似度最高的所述目标标注内容作为所述未标注医学影像图像的所述标注信息。Step S220, selecting the target labeling content with the highest similarity as the labeling information of the unlabeled medical image image.
对于不同用户,系统可以发去相同或相似位置的截面。通过对不同的用户的认证,从而得到相同或相似位置的多个目标标注内容,进而根据相似度作为选择目标标注内容的权重,即为,对未标注医学影像图像圈画越准确的用户,他对未标注医学影像图像的圈画结果的决定权,大于那些对未标注医学影像图像圈画准确度不高的用户(准确度不高的用户也许达到预设相似度的标准)。For different users, the system can send cross sections of the same or similar positions. By authenticating different users, multiple target annotation contents of the same or similar positions are obtained, and then the weight of the content is marked according to the similarity as the selection target, that is, the more accurate the user is not labeled with the medical image image, he The decision-making power of the circled painting result without the medical image image is greater than those of the user who does not have the high accuracy of the unlabeled medical image image (the user with low accuracy may reach the standard of the preset similarity).
实施例5:Example 5:
参照图6,本申请第五实施例提供一种基于图像认证的医学影像标注方法,基于上述图2所示的第一实施例,所述步骤S200“利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息”之后,还包括:Referring to FIG. 6 , a fifth embodiment of the present application provides a medical image annotation method based on image authentication. Based on the first embodiment shown in FIG. 2 , the step S200 “uses the user according to the login interface according to the After the labeling the medical image image to the target labeling of the unlabeled medical image image to obtain the labeling information of the unlabeled medical image image, the method further includes:
步骤S700,获取所述预设待标记区域对应的多个不同平面的所述标注信息;Step S700: Obtain the labeling information of multiple different planes corresponding to the preset to-be-marked area;
步骤S800,对所述预设待标记区域对应的多个不同平面的所述标注信息进行合成,得到与所述预设待标记区域对应的三维标注数据。Step S800, synthesizing the annotation information of the plurality of different planes corresponding to the preset to-be-marked area, and obtaining three-dimensional annotation data corresponding to the preset to-be-marked area.
上述,当判定输入是人工操作,且进行保存后,用户对未标注医学影像图像的圈画,就成了三维图像中预设区域例如海马区域在这个特定平面的标注。对于不同用户,系统可以发出待标记区域的不同截面。不同用户在不同截面圈画的边界,例如海马区域边界,会在系统后台融合成一个三维的标注。In the above, when it is determined that the input is manually operated, and the user saves the circle of the medical image image, the preset area of the three-dimensional image, such as the hippocampus area, is marked on the specific plane. For different users, the system can issue different sections of the area to be marked. The boundaries of different users in different sections of the circle, such as the boundary of the hippocampus, will be merged into a three-dimensional annotation in the background of the system.
所述“获取医学影像库中的已标注医学影像图像和未标注医学影像图像”之前,还包括:Before the “acquiring the labeled medical image image and the unlabeled medical image image in the medical image library”, the method further includes:
步骤S900,接收所述用户的验证请求,以便于根据所述用户请求获取医学影像库中的已标注医学影像图像和未标注医学影像图像。Step S900, receiving the verification request of the user, so as to obtain the labeled medical image image and the unlabeled medical image image in the medical image library according to the user request.
上述,在用户进行对于不同的网站或客户端进行登录时,通过网站提出验证请求,从而根据该验证请求进行进一步的获取医学影像库中的已标注医学影像图像和未标注医学影像图像的操作。In the above, when the user performs login for different websites or clients, an authentication request is made through the website, thereby performing an operation of further acquiring the labeled medical image and the unlabeled medical image in the medical image library according to the verification request.
此外,本申请还提供一种基于图像认证的医学影像标注装置,包括:获取模块10和标注模块20;In addition, the present application further provides a medical image annotation device based on image authentication, comprising: an
所述获取模块10,配置成获取医学影像库中的已标注医学影像图像和未标注医学影像图像,并将所述已标注医学影像图像和所述未标注医学影像图像作为认证条件显示于登录界面;The acquiring
所述标注模块20,配置成利用用户在所述登录界面根据所述已标注医学影像图像对所述未标注医学影像图像的目标标注内容来获取所述未标注医学影像图像的标注信息。The
此外,本申请还提供一种用户终端,包括存储器以及处理器,所述存储器配置成基于图像认证的医学影像标注程序,所述处理器运行所述基于图像认证的医学影像标注程序以使所述用户终端执行如上述所述基于图像认证的医学影像标注方法。In addition, the present application further provides a user terminal, including a memory and a processor, the memory configured to be based on an image authentication medical image annotation program, the processor running the image authentication based medical image annotation program to enable the The user terminal performs a medical image annotation method based on image authentication as described above.
此外,本申请还提供一种计算机可读存储介质,所述计算机可读存储介质上存储有基于图像认证的医学影像标注程序,所述基于图像认证的医学影像标注程序被处理器执行时实现如上述所述基于图像认证的医学影像标注方法。In addition, the present application further provides a computer readable storage medium, where the computer image readable storage medium stores a medical image annotation program based on image authentication, and the image authentication based medical image annotation program is implemented by a processor, such as The medical image annotation method based on image authentication described above.
需要说明的是,在本文中,术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含,从而使得包括一系列要素的过程、方法、物品或者系统不仅包括那些要素,而且还包括没有明确列出的其他要素,或者是还包括为这种过程、方法、物品或者系统所固有的要素。在没有更多限制的情况下,由语句“包括一个……”限定的要素,并不排除在包括该要素的过程、方法、物品或者系统中还存在另外的相同要素。It is to be understood that the term "comprises", "comprising", or any other variants thereof, is intended to encompass a non-exclusive inclusion, such that a process, method, article, or It also includes other elements that are not explicitly listed, or elements that are inherent to such a process, method, item, or system. An element defined by the phrase "comprising a ..." does not exclude the presence of additional equivalent elements in a process, method, article, or system that includes the element, without further limitation.
上述本申请实施例序号仅仅为了描述,不代表实施例的优劣。The serial numbers of the embodiments of the present application are merely for the description, and do not represent the advantages and disadvantages of the embodiments.
通过以上的实施方式的描述,本领域的技术人员可以清楚地了解到上述实施例方法可借助软件加必需的通用硬件平台的方式来实现,当然也可以通过硬件,但很多情况下前者是更佳的实施方式。基于这样的理解,本申请的技术方案本质上或者说对现有技术做出贡献的部分可以以软件产品的形式体现出来,该计算机软件产品存储在如上所述的一个存储介质(如ROM/RAM、磁碟、光盘)中,包括若干指令用以使得一台终端设备(可以是手机,计算机,服务器,或者网络设备等)执行本申请各个实施例所述的方法。Through the description of the above embodiments, those skilled in the art can clearly understand that the foregoing embodiment method can be implemented by means of software plus a necessary general hardware platform, and of course, can also be through hardware, but in many cases, the former is better. Implementation. Based on such understanding, the technical solution of the present application, which is essential or contributes to the prior art, may be embodied in the form of a software product stored in a storage medium (such as ROM/RAM as described above). , a disk, an optical disk, including a number of instructions for causing a terminal device (which may be a mobile phone, a computer, a server, or a network device, etc.) to perform the methods described in the various embodiments of the present application.
以上仅为本申请的优选实施例,并非因此限制本申请的专利范围,凡是利用本申请说明书及附图内容所作的等效结构或等效流程变换,或直接或间接运用在其他相关的技术领域,均同理包括在本申请的专利保护范围内。The above is only a preferred embodiment of the present application, and is not intended to limit the scope of the patent application, and the equivalent structure or equivalent process transformations made by the specification and the drawings of the present application, or directly or indirectly applied to other related technical fields. The same is included in the scope of patent protection of this application.
本申请实施例提供的基于图像认证的医学影像标注方法、装置、用户终端和计算机可读存储介质,本实施例提供的方法使用户在进行登录认证的同时,实现不仅进行在线认证,又可以实现对于海量的医学图像的标注工作,从而得到海量的有标注的医学图像库,标注时间段、效率高,通过每个登录用户的认证过程进行对医学影像的标注,大大降低了标注成本,且由于人工标注,提高了标注准确率,为专业医生对于临床大量医学影像图像的标注需求带来了巨大的方便。The image authentication method, the device, the user terminal, and the computer readable storage medium are provided by the embodiment of the present application. The method provided in this embodiment enables the user to perform not only online authentication but also online authentication. For the labeling work of a large number of medical images, a large number of labeled medical image libraries are obtained, which mark time periods and high efficiency, and the medical images are marked by the authentication process of each login user, which greatly reduces the labeling cost, and Manual labeling improves the accuracy of labeling, which brings great convenience for professional doctors to label the clinical medical image.
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