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WO2019004868A3 - Combinaison d'un médicament chondroprotecteur et d'un médicament anti-inflammatoire - Google Patents

Combinaison d'un médicament chondroprotecteur et d'un médicament anti-inflammatoire Download PDF

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Publication number
WO2019004868A3
WO2019004868A3 PCT/RU2018/000345 RU2018000345W WO2019004868A3 WO 2019004868 A3 WO2019004868 A3 WO 2019004868A3 RU 2018000345 W RU2018000345 W RU 2018000345W WO 2019004868 A3 WO2019004868 A3 WO 2019004868A3
Authority
WO
WIPO (PCT)
Prior art keywords
nsaid
combination
chondroprotective agent
osteoarthritis
chondroprotective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2018/000345
Other languages
English (en)
Russian (ru)
Other versions
WO2019004868A2 (fr
Inventor
Алексей Валерьевич ЧЕКАЛОВ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Obshchestvo S Ogranichennoy Otvetstvennostyu "fbk"
Original Assignee
Obshchestvo S Ogranichennoy Otvetstvennostyu "fbk"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obshchestvo S Ogranichennoy Otvetstvennostyu "fbk" filed Critical Obshchestvo S Ogranichennoy Otvetstvennostyu "fbk"
Publication of WO2019004868A2 publication Critical patent/WO2019004868A2/fr
Publication of WO2019004868A3 publication Critical patent/WO2019004868A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un médicament peroral contenant diacéréine, chondroïtine et glucosamine et son utilisation dans le traitement de l'ostéoarthrite, des articulations périphériques, de l'ostéochondrite intervertébrale, de l'ostéoarthrite et de l'ostéoporose, de la parodontopathie et/ou pour accélérer la formation d'un cal osseux lors de fractures.
PCT/RU2018/000345 2017-06-30 2018-06-28 Combinaison d'un médicament chondroprotecteur et d'un médicament anti-inflammatoire Ceased WO2019004868A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2017123275A RU2742172C2 (ru) 2017-06-30 2017-06-30 Комбинация хондропротекторного средства с нпвс
RU2017123275 2017-06-30

Publications (2)

Publication Number Publication Date
WO2019004868A2 WO2019004868A2 (fr) 2019-01-03
WO2019004868A3 true WO2019004868A3 (fr) 2019-02-07

Family

ID=64184153

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2018/000345 Ceased WO2019004868A2 (fr) 2017-06-30 2018-06-28 Combinaison d'un médicament chondroprotecteur et d'un médicament anti-inflammatoire

Country Status (2)

Country Link
RU (1) RU2742172C2 (fr)
WO (1) WO2019004868A2 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040198695A1 (en) * 2003-04-02 2004-10-07 Anhu Li Joint-protecting beverages and/or foods and their preparations
WO2009065604A2 (fr) * 2007-11-23 2009-05-28 Bayer Consumer Care Ag Composition pharmaceutique
WO2010109256A1 (fr) * 2009-03-23 2010-09-30 Carlo Ghisalberti Traitement amélioré de lésions affectant des tissus articulatoires et des tissus conjonctifs
EP2243478A1 (fr) * 2007-09-26 2010-10-27 World Trade Import-Export, WTIE A.G. Composition pharmaceutique comprenant la combinaison d'un agent anti-arthritique et d'un agent inhibiteur de l'interleukine 1, utile pour le contrôle et le traitement de l'ostéoarthrose et de maladies associées
WO2013100882A2 (fr) * 2011-12-27 2013-07-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Combinaisons de diacéréine et d'anti-inflammatoires non stéroïdiens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2478376C1 (ru) * 2011-11-24 2013-04-10 Общество С Ограниченной Ответственностью "Консорциум-Пик" Фармацевтическая композиция на основе растительной дгк для лечения и профилактики заболеваний суставов

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040198695A1 (en) * 2003-04-02 2004-10-07 Anhu Li Joint-protecting beverages and/or foods and their preparations
EP2243478A1 (fr) * 2007-09-26 2010-10-27 World Trade Import-Export, WTIE A.G. Composition pharmaceutique comprenant la combinaison d'un agent anti-arthritique et d'un agent inhibiteur de l'interleukine 1, utile pour le contrôle et le traitement de l'ostéoarthrose et de maladies associées
WO2009065604A2 (fr) * 2007-11-23 2009-05-28 Bayer Consumer Care Ag Composition pharmaceutique
WO2010109256A1 (fr) * 2009-03-23 2010-09-30 Carlo Ghisalberti Traitement amélioré de lésions affectant des tissus articulatoires et des tissus conjonctifs
WO2013100882A2 (fr) * 2011-12-27 2013-07-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Combinaisons de diacéréine et d'anti-inflammatoires non stéroïdiens

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
E. TROFIMOV ET AL: "The effect of different treatments on the clinical course of knee osteoarthritis", OSTEOARTHRITIS AND CARTILAGE., vol. 26, 1 April 2018 (2018-04-01), GB, pages S306 - S307, XP055530990, ISSN: 1063-4584, DOI: 10.1016/j.joca.2018.02.617 *
R MIRUNALINI ET AL: "EFFICACY OF CHONDROITIN SULFATE WITH GLUCOSAMINE VERSUS DIACEREIN IN GRADE II AND III OSTEOARTHRITIS KNEE: A RANDOMIZED COMPARATIVE STUDY", ASIAN JOURNAL OF PHARMACEUTICAL AND CLINICAL RESEARCH : AJPCR, vol. 8, no. 4, 1 January 2015 (2015-01-01), IN, pages 244 - 246, XP055530976, ISSN: 0974-2441 *
STEINMEYER J ET AL: "Oral treatment options for degenerative joint disease-presence and future", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM, NL, vol. 58, no. 2, 20 May 2006 (2006-05-20), pages 168 - 211, XP024892181, ISSN: 0169-409X, [retrieved on 20060520], DOI: 10.1016/J.ADDR.2006.01.007 *

Also Published As

Publication number Publication date
RU2017123275A3 (fr) 2019-01-09
WO2019004868A2 (fr) 2019-01-03
RU2017123275A (ru) 2019-01-09
RU2742172C2 (ru) 2021-02-02

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