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WO2019003245A1 - Multispectral optical imaging device and method for contactless functional imaging of skin - Google Patents

Multispectral optical imaging device and method for contactless functional imaging of skin Download PDF

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Publication number
WO2019003245A1
WO2019003245A1 PCT/IN2018/050418 IN2018050418W WO2019003245A1 WO 2019003245 A1 WO2019003245 A1 WO 2019003245A1 IN 2018050418 W IN2018050418 W IN 2018050418W WO 2019003245 A1 WO2019003245 A1 WO 2019003245A1
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WIPO (PCT)
Prior art keywords
user
multispectral
server
images
imaging
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Ceased
Application number
PCT/IN2018/050418
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French (fr)
Inventor
Sheet DEBDOOT
Basak KAUSIK
Ojha TAMOGHNA
Karri Phani KRISHNA
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Skincurate Research Private Ltd
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Skincurate Research Private Ltd
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Publication of WO2019003245A1 publication Critical patent/WO2019003245A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898—Portable consumer electronic devices, e.g. music players, telephones, tablet computers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Definitions

  • the present invention relates to an optical imaging device and associated hardware- software co-designed technology.
  • the present invention aims at noninvasive, contactless, point-of-care and real-time functional imaging of skin conditions for screening, early diagnosis, monitoring and prognosis and a method for the same.
  • Dermatoscopy utilizes the use of dermatoscope for examining skin lesions and has a low diagnostic specificity of current screening. These are usually in the form of a handheld device or a smart phone attachment and assist in screening of skin lesions. Some generations of dermatoscope can only capture high resolution images with improved optics and illumination, thus limited to only doctors or clinicians for screening of skin lesions. Other generations come with an attachment to smart phones with hardware and software co-designed platform, thereby facilitating the transfer of the images to neighborhood doctors for screening and clinical inference.
  • Histopathology is the microscopic examination of biological tissue. It suffers from trauma associated with invasive biopsy and prolonged period of intervention. Often, it may lead to psychiatric disorders which hamper their healing process. It is a three stage process involving biopsy of the wound tissue, followed by its biochemical processing and histological depiction for standardized clinical reporting. Although it quantifies the tissue involvement in a wound from its surface to its depth, it lacks in the context of being an invasive, ex vivo and time consuming procedure.
  • constellation Another technique known as constellation which provides a cost-effective and fast scanning of skin moles for early detection of skin cancer.
  • the process involves digital imaging of moles and stitching of images, followed by transmission of images over cloud.
  • a graphical modelling based algorithm, working on the cloud, will analyze the changes of skin moles over time.
  • WO2014190091A1 relates to a system and method for imaging a patient user's body part is disclosed.
  • the method may include selecting an optical imaging device to image the patient user's body part, acquiring one or more data sets with the optical imaging device, the acquiring is performed with focus at multiple axial positions and exposure control or deliberate focus at specified image locations and exposure control, registering the acquired data sets, performing image processing on the acquired data sets and recombining good data from the image processed data sets into a single image of the patient user's body parts.
  • the main object of the present invention is to overcome the limitations of the prior art.
  • An object of the present invention is to provide a portable and hand-held multispectral optical imaging device and a method for noninvasive and real-time functional imaging of skin conditions with limited user expertise for screening, early diagnosis, monitoring and prognosis.
  • Another object of the present invention is to provide device that can be used as a hardware attachment over smart phone devices or used as a standalone device.
  • Another object of the present invention is to provide a device that employs physics of tissue photon interaction and advance machine learning techniques for analysis of captured multispectral images for precise screening.
  • Another object of the present invention is to provide a device that tracks the changes of the skin conditions along the timeline.
  • Yet another object of the present invention is to provide a device that delivers point-of-care diagnostics without the need of undertaking invasive biopsy.
  • Yet another object of the present invention is to provide a device that enables high-precision and high through-put screening results of different skin conditions and facilitates periodic monitoring and prognostic inference of different skin abnormalities.
  • the present invention is envisioned towards a portable and hand-held multispectral optical imaging device (as a smartphone attachment or a standalone device) for noninvasive and real-time functional imaging of skin conditions with limited user expertise for screening, early diagnosis and monitoring.
  • the optical imaging device comprises of at least one LED based structured multispectral illumination system; a driver circuit to trigger the LEDs at different spectrum of illumination; a user based platform/interface distributed over cloud to facilitate the communication between device and the user and a computational imaging server for processing images according to the user's requirement and transferring the inferences back to the user's device.
  • the method of operation of said device comprises the steps of; actuating the camera by the user platform/interface on a smartphone or the imaging sensor on the standalone device for image acquisition; transferring acquired multispectral images to a cloud based computational imaging server for processing of said images; and transferring back clinical inference to the device for clinical assistance and future references.
  • Figure 1 illustrates a schematic representation of the device along with the components, according to an exemplary embodiment of the present invention.
  • the device that can be used as a hardware attachment over smart-phone devices or used as standalone device.
  • the optical imaging device comprises of at least one LED based structured multispectral illumination system; a driver circuit to trigger the LEDs at different spectrum of illumination; a user based platform/interface distributed over cloud to facilitate the communication between device and the user and a computational imaging server for processing images according to the user's requirement and transferring the inferences back to the user's device.
  • Figure 1 illustrates the schematic representation of the product which is a combination of a Smartphone and Multispectral Structured Illumination(MSI) hardware to generate Multispectral Image Sequence Acquisition.
  • MSI Multispectral Structured Illumination
  • the method of operation of said device comprises the steps of; actuating the camera by the user platform/interface on a smart-phone or the imaging sensor on the standalone device for image acquisition; transferring acquired multispectral images to a cloud based computational imaging server for processing of said images; and transferring back clinical inference to the device for clinical assistance and future reference.
  • the present invention is basically a hardware-software co-designed system for low-cost, non-invasive, real-time and contactless multispectral imaging through machine learning techniques to enable patient comfort centric and in situ functional characterization of skin tissue.
  • a statistical learner is modeled based on the physics of tissue photon interaction in multiple wavelength regimes of the multi spectral images of skin.
  • the device is associated with computational software services distributed over cloud that provides a complete suite of image based diagnosis.
  • the computational imaging server also maintains record of the user's images and re-processes them over time for patient centric tractability and diagnosis.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Business, Economics & Management (AREA)
  • General Business, Economics & Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Multimedia (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The present invention relates to a multispectral optical imaging device, comprising; LED based structured multispectral illumination system; a driver circuit that triggers plurality of LEDs at different spectrum of illumination; a user-based platform/interface distributed over cloud that facilitates the communication between said device and a user; and a computational imaging server to process images according to server requirement and transfers the inferences back to device. The method of operation comprises the steps of actuating a camera by the user platform/interface on a smart-phone or the imaging sensor on the standalone device for image acquisition; transferring acquired multispectral images to a cloud based computational imaging server for processing of images; and transferring back clinical inferences to the device for clinical assistance and future reference.

Description

MULTISPECTRAL OPTICAL IMAGING DEVICE AND COMPUTATIONAL TECHNIQUES FOR CONTACTLESS FUNCTIONAL IMAGING OF SKIN
FIELD OF THE INVENTION
[0001] The present invention relates to an optical imaging device and associated hardware- software co-designed technology. In particular, the present invention aims at noninvasive, contactless, point-of-care and real-time functional imaging of skin conditions for screening, early diagnosis, monitoring and prognosis and a method for the same.
BACKGROUND OF THE INVENTION
[0002] Currently, there are a range of skin based diseases (such as acne, basal cell carcinoma, melanoma, psoriasis, vitiligo, impetigo etc.) that pervade all cultures and ages of population, affecting the physical health including psychological and social complications across the globe. There are various techniques available for screening and monitoring of skin related diseases. These techniques include dermatoscopy, histopathology and constellation.
[0003] Dermatoscopy utilizes the use of dermatoscope for examining skin lesions and has a low diagnostic specificity of current screening. These are usually in the form of a handheld device or a smart phone attachment and assist in screening of skin lesions. Some generations of dermatoscope can only capture high resolution images with improved optics and illumination, thus limited to only doctors or clinicians for screening of skin lesions. Other generations come with an attachment to smart phones with hardware and software co-designed platform, thereby facilitating the transfer of the images to neighborhood doctors for screening and clinical inference.
[0004] Histopathology is the microscopic examination of biological tissue. It suffers from trauma associated with invasive biopsy and prolonged period of intervention. Often, it may lead to psychiatric disorders which hamper their healing process. It is a three stage process involving biopsy of the wound tissue, followed by its biochemical processing and histological depiction for standardized clinical reporting. Although it quantifies the tissue involvement in a wound from its surface to its depth, it lacks in the context of being an invasive, ex vivo and time consuming procedure.
[0005] Another technique known as constellation which provides a cost-effective and fast scanning of skin moles for early detection of skin cancer. The process involves digital imaging of moles and stitching of images, followed by transmission of images over cloud. A graphical modelling based algorithm, working on the cloud, will analyze the changes of skin moles over time.
[0006] WO2014190091A1 relates to a system and method for imaging a patient user's body part is disclosed. The method may include selecting an optical imaging device to image the patient user's body part, acquiring one or more data sets with the optical imaging device, the acquiring is performed with focus at multiple axial positions and exposure control or deliberate focus at specified image locations and exposure control, registering the acquired data sets, performing image processing on the acquired data sets and recombining good data from the image processed data sets into a single image of the patient user's body parts.
[0007] However, existing techniques require a user to be technically expert for early diagnosis and monitoring of skin related diseases. Moreover, existing techniques are quite expensive and not effective.
[0008] Therefore, in light of the foregoing discussion, there exist problems associated with conventional techniques for skin related screening and diagnostic purposes. There is a need of an optical imaging device for non-invasive and real time functional imaging of skin conditions and can be used by semi-skilled healthcare workers and paramedics.
OBJECT OF THE INVENTION
[0009] The main object of the present invention is to overcome the limitations of the prior art.
[0010] An object of the present invention is to provide a portable and hand-held multispectral optical imaging device and a method for noninvasive and real-time functional imaging of skin conditions with limited user expertise for screening, early diagnosis, monitoring and prognosis.
[0011] Another object of the present invention is to provide device that can be used as a hardware attachment over smart phone devices or used as a standalone device. [0012] Another object of the present invention is to provide a device that employs physics of tissue photon interaction and advance machine learning techniques for analysis of captured multispectral images for precise screening.
[0013] Another object of the present invention is to provide a device that tracks the changes of the skin conditions along the timeline.
[0014] Yet another object of the present invention is to provide a device that delivers point-of-care diagnostics without the need of undertaking invasive biopsy.
[0015] Yet another object of the present invention is to provide a device that enables high-precision and high through-put screening results of different skin conditions and facilitates periodic monitoring and prognostic inference of different skin abnormalities.
[0016] The foregoing and other objects, features, and advantages of the present invention will become readily apparent upon further review of the following detailed description of the preferred embodiment as illustrated in the accompanying drawings.
SUMMARY OF THE INVENTION
[0017] The present invention is envisioned towards a portable and hand-held multispectral optical imaging device (as a smartphone attachment or a standalone device) for noninvasive and real-time functional imaging of skin conditions with limited user expertise for screening, early diagnosis and monitoring.
[0018] According to an embodiment of the present invention, the optical imaging device comprises of at least one LED based structured multispectral illumination system; a driver circuit to trigger the LEDs at different spectrum of illumination; a user based platform/interface distributed over cloud to facilitate the communication between device and the user and a computational imaging server for processing images according to the user's requirement and transferring the inferences back to the user's device.
[0019] In an another embodiment of the present invention, the method of operation of said device, comprises the steps of; actuating the camera by the user platform/interface on a smartphone or the imaging sensor on the standalone device for image acquisition; transferring acquired multispectral images to a cloud based computational imaging server for processing of said images; and transferring back clinical inference to the device for clinical assistance and future references.
BRIEF DESCRIPTION OF DRAWINGS
[0020] The present invention is best understood with reference to the accompanying drawing, which are,
Figure 1 illustrates a schematic representation of the device along with the components, according to an exemplary embodiment of the present invention.
DETAILED DESCRIPTION OF THE INVENTION
[0021] As required, detailed embodiments of the present invention are disclosed herein; however, it is to be understood that the disclosed embodiments are merely exemplary of the invention which may be embodied in various forms. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but merely as a basis for the claims and as a representative basis for teaching one skilled in the art to variously employ the present invention in virtually any appropriately detailed structure.
[0022] Various other objects, advantages, and features of the invention will become more readily apparent to those skilled in the art from the following detailed description when read in conjunction with the accompanying drawings, in which like reference numerals designate like parts throughout the figures thereof.
[0023] Modifications to embodiments of the present disclosure described in the foregoing are possible without departing from the scope of the present disclosure as defined by the accompanying claims. Expressions such as "including", "comprising", "incorporating", "have", "is" used to describe and claim the present disclosure are intended to be construed in a non-exclusive manner, namely allowing for items, components or elements not explicitly described also to be present. Reference to the singular is also to be construed to relate to the plural. [0024] The present invention relates to a portable and hand-held multispectral optical imaging device and method for noninvasive, contactless, point-of-care and real-time functional imaging of skin conditions with limited user expertise for screening, early diagnosis and monitoring.
[0025] The device that can be used as a hardware attachment over smart-phone devices or used as standalone device.
[0026] The optical imaging device comprises of at least one LED based structured multispectral illumination system; a driver circuit to trigger the LEDs at different spectrum of illumination; a user based platform/interface distributed over cloud to facilitate the communication between device and the user and a computational imaging server for processing images according to the user's requirement and transferring the inferences back to the user's device.
[0027] Figure 1 illustrates the schematic representation of the product which is a combination of a Smartphone and Multispectral Structured Illumination(MSI) hardware to generate Multispectral Image Sequence Acquisition.
[0028] The method of operation of said device comprises the steps of; actuating the camera by the user platform/interface on a smart-phone or the imaging sensor on the standalone device for image acquisition; transferring acquired multispectral images to a cloud based computational imaging server for processing of said images; and transferring back clinical inference to the device for clinical assistance and future reference.
[0029] The present invention is basically a hardware-software co-designed system for low-cost, non-invasive, real-time and contactless multispectral imaging through machine learning techniques to enable patient comfort centric and in situ functional characterization of skin tissue.
[0030] At the server end, a statistical learner is modeled based on the physics of tissue photon interaction in multiple wavelength regimes of the multi spectral images of skin. [0031] In an alternate embodiment, the device is associated with computational software services distributed over cloud that provides a complete suite of image based diagnosis.
[0032] The services are invoked at the server to process these images according to the user's requirement and the inferences are again transferred back to the user's device.
[0033] The computational imaging server also maintains record of the user's images and re-processes them over time for patient centric tractability and diagnosis.
[0034] While the disclosure has been presented with respect to certain specific embodiments, it will be appreciated that many modifications and changes may be made by those skilled in the art without departing from the spirit and scope of the disclosure. It is intended, therefore, by the appended claims to cover all such modifications and changes as fall within the true spirit and scope of the disclosure.

Claims

CLAIMS: WHAT IS CLAIMED IS:
1. A multispectral optical imaging device, comprising;
at least one LED based structured multispectral illumination system;
a driver circuit, wherein said circuit triggers plurality of LEDs at different spectrum of illumination;
a user based platform/interface distributed over cloud, wherein said user based platform/interface facilitates the communication between said device and a user; and
a computational imaging server, wherein said server processes images according to said server requirement and transfers the inferences back to said device.
2. The device as claimed in Claim 1, wherein said device can be used as a hardware attachment over smart-phone devices or used as standalone device.
3. The device as claimed in Claim 1, wherein said device delivers point-of-care diagnostics without the need of undertaking invasive biopsy.
4. The device as claimed in Claim 1, wherein said device tracks the changes of the skin conditions along the timeline.
5. The method of operation of said device as claimed in Claim 1, comprises the steps of;
• actuating a camera by the user platform/interface on a smart-phone or the imaging sensor on the standalone device for image acquisition;
• transferring acquired multispectral images to a cloud based computational imaging server for processing of said images; and
transferring back clinical inference to the device for clinical assistance and reference.
PCT/IN2018/050418 2017-06-28 2018-06-26 Multispectral optical imaging device and method for contactless functional imaging of skin Ceased WO2019003245A1 (en)

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IN201731022695 2017-06-28
IN201731022695 2017-06-28

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11883128B2 (en) 2016-08-24 2024-01-30 Mimosa Diagnostics Inc. Multispectral mobile tissue assessment
US12201400B2 (en) 2022-03-01 2025-01-21 Mimosa Diagnostics Inc. Releasable portable imaging device for multispectral mobile tissue assessment via determining driving intensity correction for LEDs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008111994A1 (en) * 2006-07-19 2008-09-18 Lumidigm, Inc. Spectral biometrics sensor
WO2016069788A1 (en) * 2014-10-29 2016-05-06 Spectral Md, Inc. Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification
WO2017074505A1 (en) * 2015-10-28 2017-05-04 Spectral Md, Inc. Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008111994A1 (en) * 2006-07-19 2008-09-18 Lumidigm, Inc. Spectral biometrics sensor
WO2016069788A1 (en) * 2014-10-29 2016-05-06 Spectral Md, Inc. Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification
WO2017074505A1 (en) * 2015-10-28 2017-05-04 Spectral Md, Inc. Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11883128B2 (en) 2016-08-24 2024-01-30 Mimosa Diagnostics Inc. Multispectral mobile tissue assessment
US12201400B2 (en) 2022-03-01 2025-01-21 Mimosa Diagnostics Inc. Releasable portable imaging device for multispectral mobile tissue assessment via determining driving intensity correction for LEDs

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