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WO2019090125A3 - Système d'administration de médicament transdermique anti-abus intelligent - Google Patents

Système d'administration de médicament transdermique anti-abus intelligent Download PDF

Info

Publication number
WO2019090125A3
WO2019090125A3 PCT/US2018/059026 US2018059026W WO2019090125A3 WO 2019090125 A3 WO2019090125 A3 WO 2019090125A3 US 2018059026 W US2018059026 W US 2018059026W WO 2019090125 A3 WO2019090125 A3 WO 2019090125A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
transdermal drug
abuse
smart
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2018/059026
Other languages
English (en)
Other versions
WO2019090125A2 (fr
Inventor
Navdeep KAUR
Anubhav Arora
Aofie MULLIGAN
Kevin GELSTON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chrono Therapeutics Inc
Original Assignee
Chrono Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chrono Therapeutics Inc filed Critical Chrono Therapeutics Inc
Publication of WO2019090125A2 publication Critical patent/WO2019090125A2/fr
Publication of WO2019090125A3 publication Critical patent/WO2019090125A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un dispositif d'administration de médicament transdermique comprend un réservoir, une membrane d'administration de médicament transdermique, et un trajet de fluide entre le réservoir et la membrane d'administration de médicament transdermique. Le réservoir comprend une formulation de gel ayant un agoniste opioïde. La membrane d'administration de médicament transdermique est conçue pour entrer en contact avec la peau d'un patient afin de délivrer l'agoniste opioïde sur la peau.
PCT/US2018/059026 2017-11-02 2018-11-02 Système d'administration de médicament transdermique anti-abus intelligent Ceased WO2019090125A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201762580884P 2017-11-02 2017-11-02
US201762580895P 2017-11-02 2017-11-02
US62/580,884 2017-11-02
US62/580,895 2017-11-02
US201862616340P 2018-01-11 2018-01-11
US62/616,340 2018-01-11
US201862732952P 2018-09-18 2018-09-18
US62/732,952 2018-09-18

Publications (2)

Publication Number Publication Date
WO2019090125A2 WO2019090125A2 (fr) 2019-05-09
WO2019090125A3 true WO2019090125A3 (fr) 2020-04-02

Family

ID=66331474

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2018/059026 Ceased WO2019090125A2 (fr) 2017-11-02 2018-11-02 Système d'administration de médicament transdermique anti-abus intelligent

Country Status (1)

Country Link
WO (1) WO2019090125A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3049529A1 (fr) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Dispositifs et methodes d'administration transdermique de medicament
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
EP3880175A4 (fr) 2018-11-16 2022-08-17 Morningside Venture Investments Limited Système d'administration transdermique de médicaments à régulation thermique
WO2024249305A2 (fr) * 2023-05-26 2024-12-05 Ategenos Pharmaceuticals Inc. Système d'administration de médicament transdermique et ses utilisations
US12329861B2 (en) 2023-05-26 2025-06-17 Ategenos Pharmaceuticals Inc. Transdermal drug delivery system and uses thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005081825A2 (fr) * 2004-02-23 2005-09-09 Euro-Celtique S.A. Dispositif de distribution transdermique d'opioides empechant une utilisation abusive et contenant des microspheres d'antagonistes d'opioides
WO2007041544A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Systemes d'administration transdermique de medicament, dispositifs, et methodes faisant intervenir un agoniste opioide et/ou un antagoniste opioide
US8481560B2 (en) * 2010-04-02 2013-07-09 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20160220798A1 (en) * 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
WO2005081825A2 (fr) * 2004-02-23 2005-09-09 Euro-Celtique S.A. Dispositif de distribution transdermique d'opioides empechant une utilisation abusive et contenant des microspheres d'antagonistes d'opioides
WO2007041544A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Systemes d'administration transdermique de medicament, dispositifs, et methodes faisant intervenir un agoniste opioide et/ou un antagoniste opioide
US8481560B2 (en) * 2010-04-02 2013-07-09 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
US20160220798A1 (en) * 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems

Also Published As

Publication number Publication date
WO2019090125A2 (fr) 2019-05-09

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