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WO2019068563A1 - Composition dépourvue d'eau et son utilisation cosmétique - Google Patents

Composition dépourvue d'eau et son utilisation cosmétique Download PDF

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Publication number
WO2019068563A1
WO2019068563A1 PCT/EP2018/076336 EP2018076336W WO2019068563A1 WO 2019068563 A1 WO2019068563 A1 WO 2019068563A1 EP 2018076336 W EP2018076336 W EP 2018076336W WO 2019068563 A1 WO2019068563 A1 WO 2019068563A1
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Prior art keywords
composition
oil
composition according
component
vitamin
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Ceased
Application number
PCT/EP2018/076336
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English (en)
Inventor
Sophia Morgan
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Individual
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Individual
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Publication of WO2019068563A1 publication Critical patent/WO2019068563A1/fr
Anticipated expiration legal-status Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29—Titanium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/14—Preparations for removing make-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A61K2800/31—Anhydrous

Definitions

  • the present invention relates to a water free composition comprising Cocos nucifera oil. Furthermore, the present invention relates to a personal care product and a kit comprising said composition. The present invention also relates to the use of said composition as a cosmetic, and use in a personal care product.
  • compositions exist for the removal of make-up from the face and the eyes.
  • these compositions are based on the use of surfactants, which may be irritating to the skin and cause drying of the skin due to removal of the natural oil film of the skin. The latter causes the sebaceous glands to subsequently overproduce oil, a condition known as reactive seborrhoea, which might lead to clogged pores.
  • some surfactant based compositions have a pH value that is much higher than pH of the skin, which may favour growth of some types of bacteria on the skin, causing acne.
  • Many make-up products, such as lipstick, mascara, and foundation are oil-based and leave an oil-containing residue on the skin surface that cannot be easily removed. Today, many make-up products are waterproof and long-lasting, which makes them more difficult to remove. Removal of such oil-based products is generally performed with the aid of a make-up remover based on oil, such as two-phase compositions.
  • make-up removal products are purely based on oils. However, many of these make-up removal products are often so unpleasant to apply due to solid state of the oil in room temperature, that it is preferable to use a classical cleansing lotion containing surfactants. In addition, many of these make-up removal products leave on an unpleasant greasy residue. Another issue with make-up removal products is that they usually comprise preservatives, such as stabilizers and anti-bacterial agents. These ingredients may cause irritation of the skin.
  • the present invention relates to water free, oil based compositions.
  • the present invention comprises compositions useful for efficient removal of make-up and impurities from the face, without leaving a greasy residue.
  • the formulation can be used to remove make-up and impurities from the face while leaving skin with a moisturized, smooth feeling and healthy glow.
  • the present invention concerns a composition comprising Cocos nucifera oil.
  • the present invention also concerns a personal care product comprising said composition. Furthermore, the present invention concerns a kit comprising said composition.
  • the present invention concerns a method for manufacturing said composition, comprising mixing at least two of the components defined herein.
  • the present invention concerns use of said composition as a cosmetic, and use in a personal care product.
  • the present invention concerns a composition comprising Cocos nucifera oil.
  • Cocos nucifera oil is the fixed oil obtained by expression of the kernels of the seeds of the coconut, Cocos nucifera L, Palmaceae.
  • the composition comprises at least 5 % (v/v), such as at least 10 % (v/v), such as at least 20 % (v/v), such as at least 30 % (v/v), such as at least 40 % (v/v), such as at least 50 % (v/v), such as at least 60 % (v/v) Cocos nucifera oil.
  • the composition comprises no more than 70 % (v/v), such as no more than 60 % (v/v), such as no more than 50 % (v/v), such as no more than 40 % (v/v), such as no more than 30 % (v/v), such as no more than 20 % (v/v) Cocos nucifera oil.
  • the composition comprises 10 to 30 % (v/v), such as 15 to 25 % (v/v), such as 20 % (v/v) Cocos nucifera oil.
  • the composition further comprises Component A.
  • component A is Coco-caprylate/caprate. Coco-caprylate/caprate consists of alcohols, coco, mixed esters with octanoic and decanoic acids.
  • Component A is Hydrogenated Ethylhexyl Olivate and/or Hydrogenated Olive Oil Unsaponifiables. In one embodiment, Component A is
  • Hydrogenated Ethylhexyl Olivate is a mixture of esters produced by the reaction of ethylhexanol and Hydrogenated Olive Oil, and Hydrogenated Olive Oil Unsaponifiables is Olive oil, unsaponifiable fraction, hydrogenated.
  • the composition comprises at least 10 % (v/v), such as at least 20 % (v/v), such as at least 30 % (v/v), such as at least 40 % (v/v), such as at least 50 % (v/v), such as at least 60 % (v/v), such as at least 70 % (v/v), such as at least 80 %
  • the composition comprises no more than 95 % (v/v), such as no more than 90 % (v/v), such as no more than 80 % (v/v), such as no more than 70 % (v/v), such as no more than 60 % (v/v), such as no more than 50 % (v/v), such as no more than 40 % (v/v), such as no more than 30 % (v/v), such as no more than 20 % (v/v) Component A.
  • the composition comprises 60 to 85 % (v/v), such as 65 to 85 % (v/v), such as 70 to 80 % (v/v) Component A.
  • the composition further comprises Tocopheryl Acetate (Vitamin E, (2R)-2,5,7,8-tetrametyl-2-[(4R,8R)-(4,8,12-trimetyltridecyl)]-6-kromanol).
  • the composition comprises at least 0.1 % (v/v), such as at least 0.25 % (v/v), such as at least 0.5 % (v/v), such as at least 0.75 % (v/v) such as at least 1 % (v/v) Vitamin E.
  • the composition comprises no more than 5 % (v/v), no more than 4 % (v/v), no more than 3 % (v/v), no more than 2 % (v/v), no more than 1 % (v/v) Vitamin E.
  • the composition comprises 0.5 to 2 % (v/v), such as 1 % (v/v) Vitamin E.
  • the composition further comprises MICA (Color Index (CI) No. 77019; CAS No. 12001 -26-2).
  • MICA is a naturally occurring mineral dust often used as color additive in cosmetics, e.g. allowing for a shimmery effect. According to W. A. Deer, R. A. Howie and J. Zussman (1966) in "An Introduction to the Rock Forming
  • MICA can be chemically characterized by the general formula:
  • X is K, Na, or Ca or less commonly Ba, Rb, or Cs;
  • Y is Al, Mg, or Fe or less commonly Mn, Cr, Ti, Li, etc.;
  • Z is chiefly Si or Al, but also may include Fe 3+ or Ti.
  • the composition comprises no more than 1 % MICA. In one embodiment, the composition further comprises carrot root extract. In one embodiment, the carrot root extract is Daucus carota sativa carrot root extract. Daucus carota sativa root extract is an extract of the roots of the carrot, Daucus carota L. var. sativa.
  • the composition further comprises sunflower seed oil.
  • the sunflower seed oil is Helianthus annuus seed oil.
  • the composition further comprises jojoba seed oil.
  • Said jojoba seed oil may be Simmondsia chinensis seed oil.
  • Simmondsia chinensis seed oil is the fixed oil expressed or extracted from seeds of the desert shrub, Jojoba, Simmondsia chinensis, Buxaceae.
  • the composition further comprises sea buckthorn fruit oil.
  • the sea buckthorn fruit oil is Hippophae rhamnoides fruit oil.
  • Hippophae rhamnoides fruit oil is the oil expressed from the fruit of the Sea Buckthorn, Hippophae rhamnoides L, Elaeagnaceae.
  • the composition further comprises titanium dioxide or zinc oxide. Micronized and nano-scale titanium dioxide and zinc oxide provide strong protection against UVA and UVB ultraviolet radiation.
  • the composition further comprises karanja oil.
  • Karanja oil is also known as Pongamia glabra seed oil, which is the fixed oil expressed from seeds of Pongamia glabra, Fabaceae.
  • the composition further comprises essential oil.
  • essential oil refers to a concentrated hydrophobic liquid containing volatile aroma compounds from plants.
  • Essential oils are also known as volatile oils, ethereal oils, aetherolea, or simply as the oil of the plant from which they were extracted.
  • the essential oil is Pelargonium Graveolens Flower Oil.
  • the essential oil is selected from the group consisting of Raspberry oil, Wheatgerm oil, Macadamia oil, Apricot oil, Hempseed oil, Grapeseed oil, and Ricebran oil.
  • the composition may be substantially free from water. Without containing water or needing to be rinsed of with water, the formulation can be used to remove make-up and impurities from the face while leaving skin with a moisturized, smooth feeling and healthy glow.
  • the composition comprises less than 5 % of water, such as less than 4 %, such as less than 3 %, such as less than 2 %, such as less than 1 %, such as less than 0.5 % of water.
  • no water is added to the composition.
  • composition In case the composition is substantially free from water, the requirement of preservatives such as stabilizers and anti-bacterial agents is reduced, which means that less components are required in the composition compared to other make-up removers that comprise water. Apart from being beneficial from an environmental aspect, it is also beneficial from a consumer aspect, since preservatives may cause skin irritation.
  • the composition further comprises an antibacterial agent.
  • Said antibacterial agent may be a probiotic.
  • the antibacterial agent is Bacillus clausii spores.
  • the composition comprises 1 to 5 % (v/v) of a Bacillus clausii spores-water mixture, wherein the concentration of Bacillus clausii spores in the Bacillus clausii spores-water mixture may be 0.4 billion Bacillus clausii spores per mL of sterile water.
  • the composition comprises 1 to 5 % (v/v) of a Bacillus clausii spores-oil mixture, wherein the concentration of Bacillus clausii spores in the Bacillus clausii spores-oil mixture may be 0.4 billion Bacillus clausii spores per mL of oil.
  • Said oil may be sunflower oil.
  • the Bacillus clausii spores-water or -oil mixture further comprises Cetearyl Glucoside.
  • the composition further comprises one or more components selected from the group consisting of karanja oil, carrot oil, argan oil, rasberry oil, shea oil, olive oil, rice oil, sunflower oil, canola oil, jojoba oil, Camelina sativa seed oil, Rosa canina seed oil, Camelia oleifera oil, Nigella sativa oil, Prunus amygdalus dulcis oil, Vaccinium macrocarpon seed oil, Sesamum indicum seed oil, Ribes nigrum seed oil and Rosmarinus officinalis leaf extract.
  • karanja oil carrot oil, argan oil, rasberry oil, shea oil, olive oil, rice oil, sunflower oil, canola oil, jojoba oil, Camelina sativa seed oil, Rosa canina seed oil, Camelia oleifera oil, Nigella sativa oil, Prunus amygdalus dulcis oil, Vaccinium macrocarpon seed oil, Sesamum in
  • the composition further comprises one or more components selected from the group consisting of Ricinus communis seed oil, Sclerocarya birrea seed oil, Damia integrifolia seed oil, Pongamia glabra seed oil, Opuntia ficus-indica seed oil, Hippophae rhamnoides fruit oil, Cannabis sativa seed oil, Borago officinalis seed oil, Punica granatum seed oil, Vitis vinifera seed oil, Brassica oleracea italica seed oil, Adansonia digitata seed oil, Baobab oil, Persea gratissima oil, Prunus armeniaca kernel oil and Sacha Inchi oil.
  • the composition consists, or consists essentially, of a number of components.
  • trace amount refers to a small amount. In one embodiment, “trace amount” refers to an amount that is detectable but not able to be quantified. In another embodiment, “trace amount” refers to no more than 1 % (w/v), such as no more than 0.5 % (w/v), such as no more than 0.1 % (w/v) of the composition.
  • le composition comprises:
  • the composition comprises:
  • composition consists essentially of:
  • the composition consists essentially of: a. 20 % (v/v) of Cocos nucifera oil; and b. 79 % (v/v) of Component A; and c. 1 % (v/v) of Vitamin E; and d. Trace amounts of MICA.
  • the composition comprises:
  • Cocos nucifera oil a. Cocos nucifera oil; and b. Component A; and
  • the composition comprises:
  • Cocos nucifera oil a. Cocos nucifera oil; and b. Component A; and
  • composition comprises
  • Cocos nucifera oil a. Cocos nucifera oil; and b. Component A; and
  • the composition comprises:
  • the composition essentially consists of: a. Cocos nucifera oil; and b. Component A; and
  • composition essentially consists of:
  • the composition comprises:
  • Cocos nucifera oil a. Cocos nucifera oil; and b. Component A; and
  • the composition comprises:
  • composition essentially consists of:
  • Cocos nucifera oil a. Cocos nucifera oil; and b. Component A; and
  • composition essentially consists of:
  • the composition comprises:
  • the composition comprises:
  • composition essentially consists of:
  • composition essentially consists of:
  • MICA is optional.
  • the composition does not comprise MICA.
  • the composition further comprises biosilica from diatoms (algae).
  • the composition comprises maximum 80% biosilica, preferably 5-10%.
  • Diatoms are unicellular microscopic algae, with cell walls consisting of silicon dioxide.
  • the cell wall has a very specific pattern of tiny pores, allowing exchange of nutrients and waste products. Each pattern is species specific.
  • Benefit in cosmetic products protects from UV-light, protects skin from pollution , rehydrates skin .
  • Biosilica from diatoms naturally contains tiny amounts of water. When you mix biosilica material from Diatoms (Algae) with the composition according to any of the proceeding claims, it creates a superior composition/facial oil or serum with the potential for acting as a UV - and pollution protection on the human skin. These potential added benefits are due to the attributes of the Diatom silica.
  • the texture of the composition is also thickened and more pleasant to apply to the skin as a facial serum or cream, and because of the fact that the biosilica diatoms dissolves in the oil without any added water or emulgator it allows for the composition to still stay preservative-free.
  • Diatom silica material into composition Heat up the coconut oil to minimum 30 C, mix in the other ingredients. Let it cool. Slowly add particles of the diatom silica into the mixture and stir and/or gently press the particles until they dissolve in the oil composition.
  • composition further comprises Moringa oil. Removed particles
  • the make-up-removing or cleaning composition eliminates for example spots or stains from make-up with a pigment base; particles coming from the atmosphere; and fats present either in the make-up products or arising from an excess of sebum present on the surface of the skin.
  • a personal care product is based on oil, they easily dissolve and/or remove the majority of make-up and impurities from the face.
  • the make-up-removing or cleaning composition eliminates for example spots or stains from make-up with a pigment base; particles coming from the atmosphere; and fats present either in the make-up products or arising from an excess of sebum present on the surface of the skin.
  • the present invention concerns a personal care product comprising the composition as defined herein.
  • Said personal care product may be selected from the group consisting of a wipe, a pad, a spray, a gel, a bath, a wash, a mousse, a shampoo, a rinse, a cream, a brush, a sponge, a cotton swab, a hair oil.
  • said personal care product is a wipe, a pad or a spray.
  • said personal care product is a cleanser or a moisturizer.
  • the solution can either be impregnated into an applicator such as a tissue or sponge or it can be used by itself and wiped off with cotton pads for example.
  • the solution can either be impregnated in to an applicator or used on its own, patted into the skin as an overnight treatment for example.
  • the personal care product comprises two wipes.
  • the first wipe may be soaked in the composition as defined herein.
  • cleaninger refers to a facial care product that is used to remove for example make-up, dead skin cells, oil, dirt, and other types of pollutants from the skin of the face. This helps to unclog pores and prevent skin conditions such as acne.
  • moistureturizer or emollient, as used herein refers to complex mixtures of chemical agents specially designed to make the external layers of the skin (epidermis) softer and more pliable. They increase the skin's hydration (water content) by reducing evaporation.
  • the present invention concerns a kit comprising the composition as defined herein.
  • the kit further comprises at least one component selected from the group consisting of a wipe, a pad, a sponge, a spray, a cotton swab, a brush, a pipette, a pump, a glove, and a mask. Said component may be soaked in the composition.
  • said kit comprises a first wipe soaked in the composition.
  • Said kit may further comprise a second wipe.
  • the present invention refers to a personal care product in which the first wipe is soaked in the composition according to the present invention, as defined in any one of claims 1 to 57, and the second wipe is soaked in analyte water, such as in 0-5% hypochlorous acid diluted in no more than 99% deionized water.
  • compositions of the present invention may be directed applied to the skin or may be applied onto other delivery implements such as wipes, sponges, brushes, and the like.
  • the compositions may be used in products designed to be left on the skin, wiped from the skin, or rinsed off of the skin.
  • the compositions are for topical administration
  • the present invention concerns the use of the composition as defined in herein as a cosmetic.
  • said cosmetic is for skin care.
  • the skin care comprises cleansing, preferably said cleansing is facial cleansing.
  • said cosmetic comprises make-up removal.
  • said cosmetic comprises UV-protection of the skin.
  • said cosmetic comprises moisturizing of skin.
  • the present invention concerns the use of the composition as defined in herein in a personal care product.
  • the personal care product is in the form of a wipe, a pad, a spray, a gel, a bath, a wash, a mousse, a shampoo, a rinse, a cream, a brush, or a sponge.
  • the personal care product is a cleanser or a moisturizer.
  • composition according to the present invention may preferably be used as a serum or facial/body oil.
  • the present invention concerns a method of manufacturing the composition as defined herein, wherein the method comprises mixing at least two of the components defined herein.
  • said method comprises the steps of:
  • mixing refers to the process of forming a mixture, such as stirring, shaking, agitating, vortexing and sonicating.
  • compositions comprising Cocoes nucifera oil
  • Cocoes nucifera oil was first heated to 30 ° C. The other components were then added while stirring.
  • compositions not comprising Cocoes nucifera oil For compositions not comprising Cocoes nucifera oil, all components were mixed while stirring.
  • the facial skin of a test subject was used as the substrate to investigate various compositions, according to the present invention see Table 1.
  • compositions comprising a high amount of Isopropyl mystriate left dry spots on skin and was irritating to the eyes.
  • compositions comprising Cocoes nucifera oil removed make up better from the face and left a smoother, more moisturized feeling than of sunflower oil.
  • Cocoes nucifera oil by itself leaves a more oily feeling than coconut oil mixed with a little Daucus carota sativa root extract.
  • Daucus carota sativa root extract made composition G fluid, and increased the moisturized feeling. Conclusion: The best result was obtained for composition G and I.
  • Example 3 Efficacy test on forearm Lipstick, foundation, mascara and eye shadow was applied on the inside of the forearm.
  • the composition was applied on the forearm and selected places on the face as eyelid, cheek. Napkins with 10 ml were used to clean the cosmetic products, between 5-10 strokes.
  • Each composition was evaluated according to different functions, see Table 3.
  • two commercial products were also evaluated:
  • Commercial product 1 CP1 , consisting of Aqua, Isopropyl Stearate, Glycerin,
  • Phenoxyethanol Methylparaben, Limonene, Linalool, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Benzyl Alcohol, Citronellol, Alpha-lsomethyl lonone,Geraniol, Butylphenyl Methylpropional, Benzyl Salicylate, Hexyl Cinnamal, and perfume; and Commercial product 2, CP2, consisting of Aqua, Alcohol Denat., Butylene Glycol, Salicylic Acid, PPG-26-Buteth-26, PEG-7 Glyceryl Cocoate, Sodium Hydroxide, PEG- 40 Hydrogenated Castor oil, Benzoic Acid, Menthol, Disodium EDTA, Phenoxyethanol, and perfume.
  • CP1 is Commercial product 1
  • CP2 is commercial product 2.
  • composition J was also proved better than the two commercial products.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une composition dépourvue d'eau comprenant de l'huile de Cocos nucifera. En outre, la présente invention concerne un produit de soins personnels et un kit comprenant ladite composition. La présente invention concerne également l'utilisation de ladite composition en tant que produit cosmétique, et son utilisation dans un produit de soins personnels.
PCT/EP2018/076336 2017-10-04 2018-09-27 Composition dépourvue d'eau et son utilisation cosmétique Ceased WO2019068563A1 (fr)

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EP17194743.5 2017-10-04
EP17194743 2017-10-04

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CN113749990A (zh) * 2021-07-27 2021-12-07 仙婷(广州)科技研发有限公司 一种温和油性护肤组合物及其制备方法
CN116983231A (zh) * 2023-08-21 2023-11-03 广州君奕科技有限公司 一种生物型防晒、修护屏障添加剂组合物、制备方法、应用和防晒数值的测试方法

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DATABASE GNPD [online] MINTEL; 23 November 2016 (2016-11-23), ANONYMOUS: "Ultra Hydrating Skincare Kit", XP055517167, retrieved from www.gnpd.com Database accession no. 4433151 *
DATABASE GNPD [online] MINTEL; 7 April 2017 (2017-04-07), ANONYMOUS: "Day Cream", XP055517112, retrieved from www.gnpd.com Database accession no. 4732973 *
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CN113749990A (zh) * 2021-07-27 2021-12-07 仙婷(广州)科技研发有限公司 一种温和油性护肤组合物及其制备方法
CN116983231A (zh) * 2023-08-21 2023-11-03 广州君奕科技有限公司 一种生物型防晒、修护屏障添加剂组合物、制备方法、应用和防晒数值的测试方法

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