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WO2019066357A1 - Procédé, système et support d'enregistrement lisible par ordinateur non transitoire pour la surveillance de l'urine résiduelle à l'aide de la bio-impédance - Google Patents

Procédé, système et support d'enregistrement lisible par ordinateur non transitoire pour la surveillance de l'urine résiduelle à l'aide de la bio-impédance Download PDF

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Publication number
WO2019066357A1
WO2019066357A1 PCT/KR2018/010997 KR2018010997W WO2019066357A1 WO 2019066357 A1 WO2019066357 A1 WO 2019066357A1 KR 2018010997 W KR2018010997 W KR 2018010997W WO 2019066357 A1 WO2019066357 A1 WO 2019066357A1
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Prior art keywords
user
bioimpedance
residual
correlation
urination
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PCT/KR2018/010997
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English (en)
Korean (ko)
Inventor
송지영
두경연
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Dain Technology Inc
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Dain Technology Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Definitions

  • the present invention relates to a method, system and non-transitory computer readable recording medium for monitoring residual urine using bioimpedance.
  • the present inventors propose a technique that allows the patient to easily monitor his or her residual amount based on the personalized correlation of the patient derived by calibrating the correlation between the residual amount and the bioimpedance.
  • Another object of the present invention is to easily estimate the residual amount of the user based on the personalized correlation between the residual urine volume and the bioimpedance.
  • a method of monitoring a residual urine using bioimpedance comprising the steps of: acquiring information on a user's residual volume and bioimpedance at a plurality of points of time; Obtaining a personalized correlation for the user by calibrating a correlation between the first bioimpedance measured by the user and the first bioimpedance measured from the user; And estimating a residual amount of the user at the time when the user is not present.
  • a system for monitoring a residual urine using a bioimpedance comprising: a biometric information managing unit for obtaining information on a residual amount and a bioimpedance of a user at a plurality of points of time; A correlation derivation unit for deriving a personalized correlation for the user by calibrating a correlation between the bioimpedance of the first bioimpedance and the first bioimpedance based on the first bioimpedance measured from the user and the personalized correlation to the user; And estimating a residual amount of the user at a time point at which the user is measured.
  • non-transitory computer readable recording medium for recording another method for implementing the invention, another system, and a computer program for carrying out the method.
  • the residual amount of the user can be easily estimated on the basis of the personalized correlation between the residual amount and the bioimpedance.
  • the present invention it is possible to provide a guide on the urination or urination time, the recommendation timing of the urinary frequency test, the abnormality of the bladder function, or the urination behavior treatment based on the estimated residual urine volume.
  • the present invention it is possible to generate and manage the urination diary based on the estimated residual urine volume of the user.
  • FIG. 1 is a diagram showing a schematic configuration of an overall system for monitoring residual urine according to an embodiment of the present invention.
  • FIG. 2 is a detailed diagram illustrating an internal configuration of a residual urine monitoring system according to an embodiment of the present invention. Referring to FIG.
  • FIG. 3 is a diagram illustrating a process of monitoring a user's residual urine according to an embodiment of the present invention. Referring to FIG.
  • FIG. 4 is an exemplary illustration of a personalized correlation between residual volume and bioimpedance in accordance with one embodiment of the present invention.
  • 5 and 6 illustrate a process of deriving a personalized correlation by calibrating a correlation between a residual volume and a bioimpedance according to an embodiment of the present invention.
  • FIG. 1 is a diagram showing a schematic configuration of an overall system for monitoring residual urine according to an embodiment of the present invention.
  • the overall system may include a communication network 100, a residual urine monitoring system 200, a user device 300, and a bioimpedance measurement device 400 .
  • the communication network 100 may be configured without regard to communication modes such as wired communication and wireless communication, and may be a LAN (Local Area Network), a Metropolitan Area Network ), A wide area network (WAN), and the like.
  • the communication network 100 referred to herein may be the well-known Internet or World Wide Web (WWW).
  • WWW World Wide Web
  • the communication network 100 may include, at least in part, a known wire / wireless data communication network, a known telephone network, or a known wire / wireless television communication network, without being limited thereto.
  • the communication network 100 may be a wireless data communication network, such as a WiFi communication, a WiFi-Direct communication, a Long Term Evolution (LTE) communication, a Bluetooth communication (for example, a low- BLE (Bluetooth Low Energy) communication), infrared communication, ultrasonic communication, and the like.
  • a wireless data communication network such as a WiFi communication, a WiFi-Direct communication, a Long Term Evolution (LTE) communication, a Bluetooth communication (for example, a low- BLE (Bluetooth Low Energy) communication), infrared communication, ultrasonic communication, and the like.
  • the residual urine monitoring system 200 can communicate with the user device 300 and the bioimpedance measuring device 400 to be described later through the communication network 100, And the correlation between the residual amount and the bioimpedance is calibrated on the basis of the acquired information to derive a personalized correlation for the user, A function of estimating the residual amount of the user at a time point at which the first bioimpedance is measured based on the correlation and the first bioimpedance measured from the user.
  • the configuration and function of the residual urine monitoring system 200 will be described in detail through the following detailed description. Although described above with respect to the residual urine monitoring system 200, this description is exemplary and at least some of the functions or components required for the residual urine monitoring system 200 may be provided to the user device 300, It will be apparent to those skilled in the art that it may be realized within the impedance measurement device 400 or other external system (not shown) or included in the user device 300, the bioimpedance measurement device 400 or other external system (not shown) .
  • the user device 300 includes a function of enabling the user to access the residual urine monitoring system 200 or the bioimpedance measuring device 400 through the communication network 100
  • a digital device any portable digital device equipped with a memory means such as a smart phone, a tablet PC and the like and equipped with a microprocessor and capable of computing can be adopted as the user device 300 according to the present invention.
  • the user device 300 may include an application supporting the residual urine monitoring function according to the present invention.
  • Such an application may be downloaded from the residual urine monitoring system 200 or from an external application distribution server (not shown).
  • the bioimpedance measuring device 400 includes a function of allowing the user to access the residual blood glucose monitoring system 200 or the user device 300 through the communication network 100
  • FIG. 2 is a detailed diagram illustrating an internal configuration of a residual urine monitoring system 200 according to an embodiment of the present invention.
  • the residual urine monitoring system 200 includes a biometric information managing unit 210, a correlation deriving unit 220, a residual urine estimating unit 230, a recommendation information determining unit 230, A vital signs generator 240, a urination diary generation unit 250, a communication unit 260, and a control unit 270.
  • the biometric information managing unit 210, the correlation deriving unit 220, the residual urine estimating unit 230, the recommendation information determining unit 240, the urination diary generation unit 250, And the control unit 270 may be a program module in which at least some of them communicate with an external system.
  • Such a program module may be included in the residual blood glucose monitoring system 200 in the form of an operating system, an application program module or other program module, and physically stored in various known memory devices. Such a program module may also be stored in a remote storage device capable of communicating with the residual urine monitoring system 200.
  • Such program modules encompass but are not limited to routines, subroutines, programs, objects, components, data structures, etc. that perform particular tasks or implement particular abstract data types as described below in accordance with the present invention.
  • the biometric information managing unit 210 can acquire information on the residual blood amount and the bioimpedance of the user at a plurality of time points.
  • the biometric information managing unit 210 may determine the amount of residual urine measured from the user at a plurality of time points including the time of urination or urination of the user, Information about the impedance can be obtained.
  • the biometric information managing unit 210 acquires information on the residual urine volume of the user before or after urination and the amount of residual urine after urination or urination from a known ultrasound measuring device (not shown) It is possible.
  • the correlation derivation unit 220 calibrates the correlation between the residual blood volume and the bioimpedance based on the information acquired by the biometric information management unit 210, A personalized correlation can be derived.
  • the correlation derivation unit 220 may calculate a generalized or predetermined correlation between a residual amount and a bioimpedance in a direction matching a residual amount and a bioimpedance at a plurality of points of the user , It is possible to derive a personalized correlation that can be applied to the user. More specifically, according to an embodiment of the present invention, the correlation derivation unit 220 calibrates coefficients, constants, parameters, and the like of a function that mathematically defines the correlation between the residual blood amount and the bioimpedance, A personalized correlation that can be applied to the user.
  • the generalized or predetermined correlation between the residual urine volume and the bioimpedance is determined by analyzing (for example, statistical analysis) the residual amount and bioimpedance of a plurality of users, , A known correlation between the residual blood flow and the bioimpedance (for example, an inverse relationship according to bioelectrical impedance analysis (BIA)), and the like.
  • analyzing for example, statistical analysis
  • a known correlation between the residual blood flow and the bioimpedance for example, an inverse relationship according to bioelectrical impedance analysis (BIA)
  • the correlation derivation unit 220 refers to the user's personal information (for example, age, sex, country, race, height,
  • the correlation associated with the personal information of the user among the plurality of generalized correlations among the plurality of generalized correlations may be determined as a generalized or predetermined correlation between the residual blood flow and the bioimpedance to be calibrated.
  • the correlation derivation unit 220 analyzes the residual amount and bioimpedance of a user whose age is 20 out of a plurality of users, And the bioimpedance may be determined as a generalized or predeterminable correlation between the residual amount and the bioimpedance to be calibrated or a correlation between the residual impedance and the bioimpedance of 20
  • the correlation between residual urine volume and bioimpedance associated with age can be determined by a generalized or predetermined correlation between residual urine volume and bioimpedance subject to calibration.
  • the correlation derivation unit 220 calculates the correlation between the residual amount and the bioimpedance at at least one time point included in a predetermined error range among the residual amount and bioimpedance at a plurality of time points of the user, As shown in FIG.
  • the correlation derivation unit 220 refers to the residual amount and the bioimpedance that are actually measured from the user at a plurality of points of time, and determines at least one between the residual amount and the bioimpedance of the user
  • the correlation can be estimated and a highly correlated correlation that is matched with the actually measured residual blood volume and bioimpedance of the at least one estimated correlation can be determined to be a personalized correlation that can be applied to the user.
  • the correlation derivation unit 220 performs a known correlation analysis such as a statistical analysis, a machine learning (or a deep learning)
  • a known correlation analysis such as a statistical analysis, a machine learning (or a deep learning)
  • the technique allows analysis of residual urine and bioimpedance measured from the user at multiple points in time.
  • the residual estimator 230 estimates the residual urine based on the personalized correlation of the user derived by the correlation derivation unit 220 and the first bioimpedance measured from the user It is possible to estimate the residual amount of the user at the time when the first bioimpedance is measured.
  • the residual estimator 230 estimates the residual urine amount corresponding to the measured bioimpedance from the user using the correlation between the residual urine amount and the bioimpedance personalized for the user have.
  • the residual estimator 230 may be configured such that, when the correlation between the residual blood flow and the bioimpedance personalized to the user is inversely proportional to the user, the residual urine amount is 50 ml and the bioimpedance at that time is 200? , When the first living body impedance measured by the user is 100 OMEGA, the residual body mass at the first living body impedance can be estimated to be 100 ml.
  • the recommendation information determining unit 240 determines whether urine or urine reference or blindness recommendation time to be provided to the user You can decide.
  • the recommendation information determination unit 240 determines a time when a residual urine amount estimated by the user is equal to or higher than a predetermined level or a residual urine amount equal to or higher than a predetermined level is determined to exist for a predetermined time or longer, Of the urine or urine to be provided to the patient.
  • the recommendation information determination unit 240 may determine the recommendation time point of the urine screening test when the estimated residual urine amount is equal to or higher than a predetermined level (for example, 150 ml or more).
  • the recommendation information determination unit 240 refers to the estimated residual amount of the user to determine whether the user is bladder function abnormality to be provided to the user or guide the user about the urination behavior therapy .
  • the guide for treatment of urination behavior may be provided by a user at a particular point in time associated with urination therapy or training, such as by allowing the user to continue to urge the urinary bladder muscle for a predetermined period of time, May refer to information about a specific action of the user.
  • the recommendation information determination unit 240 may determine a variation pattern of the estimated residual amount of the user by using the bladder function
  • the information on the bladder function abnormality to be provided to the user can be determined and analyzed by comparing the variation pattern of the residual blood amount of the user with the normal urination pattern or the urination pattern of the urination, You can decide on a guide for treatment of urination behavior to be provided.
  • the recommendation information determination unit 240 may determine whether the at least one bladder function abnormality (or normal) pattern, the at least one normal urination pattern, or the at least one urination activity pattern, machine learning, or deep learning. < Desc / Clms Page number 13 >
  • the urination diary generation unit 250 may generate a void diary for the user based on a plurality of estimated residual urine quantities of the user.
  • the urine diary according to an embodiment of the present invention is a large intestine which records various information related to the urination of the user (specifically, it is recorded in a time-series manner) and includes information about the number of urination, the amount of residual urine, the amount of urination, the time of urination, . ≪ / RTI >
  • the communication unit 260 includes a biometric information managing unit 210, a correlation deriving unit 220, a residual urine estimating unit 230, a recommendation information determining unit 240, And transmit / receive data to / from the base station 250.
  • control unit 270 includes a biometric information managing unit 210, a correlation deriving unit 220, a residual urine estimating unit 230, a recommendation information determining unit 240,
  • the control unit 250 may control the flow of data between the communication unit 260 and the communication unit 260. That is, the control unit 270 according to the present invention controls the flow of data from / to the outside of the residual urine monitoring system 200 or the data flow between the respective components of the residual urine monitoring system 200 so that the biometric information managing unit 210, The relative derivation unit 220, the residual urine estimation unit 230, the recommendation information determination unit 240, the urination diary generation unit 250, and the communication unit 260, respectively.
  • FIG. 3 is a diagram illustrating a process of monitoring a user's residual urine according to an embodiment of the present invention. Referring to FIG.
  • FIG. 4 is an exemplary illustration of a personalized correlation between residual volume and bioimpedance in accordance with one embodiment of the present invention.
  • the user device 300 includes a residual urine monitoring system 200 according to an exemplary embodiment of the present invention (for example, a residual urine monitoring system 200 according to the present invention) (Included in the user device 300 in the form of this application).
  • the user device 300 may acquire information on the residual blood flow and bioimpedance measured from the user at a plurality of time points including a time point before the urination and a time point after the urination.
  • the user device 300 calibrates the correlation between the residual volume and the bioimpedance based on the information obtained above, thereby determining the difference between the individualized residual volume and the bioimpedance for that user A correlation can be derived.
  • the personalized correlation may be an inverse relationship 401 according to one embodiment of the present invention.
  • the user device 300 may then acquire bioimpedance from the user via the bioimpedance measurement device 400 according to one embodiment of the present invention,
  • the residual amount of the user in the bioimpedance can be estimated based on the obtained bioimpedance.
  • the user device 300 determines whether or not the urine-use recommendation time, the uric-eye examination recommendation time, the bladder function abnormality, At least one can be provided. Also, according to an embodiment of the present invention, the user device 300 can monitor the urination pattern of the user by generating a urination log for the user based on the estimated residual urine of the user.
  • 5 and 6 illustrate a process of deriving a personalized correlation by calibrating a correlation between a residual volume and a bioimpedance according to an embodiment of the present invention.
  • information on residual blood flow and bio-impedance measured from a user at a plurality of time points can be obtained.
  • a personalized correlation 503 may be derived for the user by calibrating 507 in a direction that matches the residual volume and bioimpedance 504 (e.g., parallel movement, rotational movement, etc.).
  • the residual amount of the user at the time the first bioimpedance 505 is measured 506) can be estimated.
  • information 602 regarding residual blood flow and bioimpedance measured from a user at a plurality of time points can be obtained.
  • a plurality of correlations between the user's residual volume and the bioimpedance i.e., the first correlation 601, the second correlation 603, (605) can be estimated, and a highly correlated correlation (605) matching the above measured residual amount and bioimpedance among the estimated plurality of correlations is correlated to the personalized correlation (605) .
  • the first correlation 601 and the second correlation 603 of the residual blood flow and the bioimpedance 602 of the user measured above are matched once with the residual blood flow and the bioimpedance, Since the third correlation 605 of the residual blood flow and the bioimpedance 602 measured above is matched with the residual blood flow and the bioimpedance 4 times, the third correlation 605 having the highest frequency and the matching frequency with the measured residual blood flow and bioimpedance May be derived as the personalized correlation 605 of that user.
  • the residual amount of the user at the time the first bioimpedance 606 is measured 607 can be estimated.
  • the embodiments of the present invention described above can be implemented in the form of program instructions that can be executed through various computer components and recorded in a computer-readable recording medium.
  • the computer-readable recording medium may include program commands, data files, data structures, and the like, alone or in combination.
  • the program instructions recorded on the computer-readable recording medium may be those specifically designed and configured for the present invention or may be those known and used by those skilled in the computer software arts.
  • Examples of computer-readable media include magnetic media such as hard disks, floppy disks and magnetic tape, optical recording media such as CD-ROM and DVD, magneto-optical media such as floptical disks, medium, and hardware devices specifically configured to store and execute program instructions, such as ROM, RAM, flash memory, and the like.
  • program instructions include machine language code, such as those generated by a compiler, as well as high-level language code that can be executed by a computer using an interpreter or the like.
  • the hardware device may be modified into one or more software modules for performing the processing according to the present invention, and vice versa.

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Abstract

Un aspect de la présente invention concerne un procédé pour la surveillance de l'urine résiduelle à l'aide de la bio-impédance, le procédé comprenant les étapes consistant à : acquérir des informations sur le volume d'urine résiduelle d'un utilisateur et la bio-impédance à une pluralité d'instants temporels ; en déduire une corrélation personnalisée pour l'utilisateur par l'étalonnage d'une corrélation entre le volume d'urine résiduelle et la bio-impédance sur la base des informations acquises ; et estimer le volume d'urine résiduelle de l'utilisateur à un instant temporel de mesure d'une première bio-impédance, sur la base de la corrélation personnalisée pour l'utilisateur et d'une première bio-impédance mesurée de l'utilisateur.
PCT/KR2018/010997 2017-09-27 2018-09-18 Procédé, système et support d'enregistrement lisible par ordinateur non transitoire pour la surveillance de l'urine résiduelle à l'aide de la bio-impédance Ceased WO2019066357A1 (fr)

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WO2022182794A1 (fr) * 2021-02-23 2022-09-01 C. R. Bard, Inc. Systèmes et méthodes de surveillance de la vessie non invasive et à auto-apprentissage
US11911160B2 (en) 2018-08-10 2024-02-27 C. R. Bard, Inc. Automated urine output measurement systems and methods thereof
US11931151B2 (en) 2020-12-22 2024-03-19 C. R. Bard, Inc. Automated urinary output measuring system
US12055249B2 (en) 2020-07-21 2024-08-06 C. R. Bard, Inc. Automatic fluid flow system with retractable connection
US12083261B2 (en) 2020-06-05 2024-09-10 C. R. Bard, Inc. Automated fluid output monitoring
US12246146B2 (en) 2020-12-23 2025-03-11 C. R. Bard, Inc. Automated weight based fluid output monitoring system
US12364423B2 (en) 2020-12-21 2025-07-22 C. R. Bard, Inc. Automated urinary output-measuring systems and methods
US12408853B2 (en) 2020-12-17 2025-09-09 C. R. Bard, Inc. Smart bag to measure urine output via catheter
US12446813B2 (en) 2021-08-23 2025-10-21 C. R. Bard, Inc. Automated urine output system for attachment to hospital bed

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Cited By (9)

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Publication number Priority date Publication date Assignee Title
US11911160B2 (en) 2018-08-10 2024-02-27 C. R. Bard, Inc. Automated urine output measurement systems and methods thereof
US12083261B2 (en) 2020-06-05 2024-09-10 C. R. Bard, Inc. Automated fluid output monitoring
US12055249B2 (en) 2020-07-21 2024-08-06 C. R. Bard, Inc. Automatic fluid flow system with retractable connection
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