[go: up one dir, main page]

WO2018101595A3 - 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도 - Google Patents

대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도 Download PDF

Info

Publication number
WO2018101595A3
WO2018101595A3 PCT/KR2017/010957 KR2017010957W WO2018101595A3 WO 2018101595 A3 WO2018101595 A3 WO 2018101595A3 KR 2017010957 W KR2017010957 W KR 2017010957W WO 2018101595 A3 WO2018101595 A3 WO 2018101595A3
Authority
WO
WIPO (PCT)
Prior art keywords
escherichia coli
cop
inhibiting proliferation
bacteriophage esc
pathogenic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2017/010957
Other languages
English (en)
French (fr)
Other versions
WO2018101595A2 (ko
Inventor
윤성준
전수연
백형록
손지수
강상현
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intron Biotechnology Inc
Original Assignee
Intron Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intron Biotechnology Inc filed Critical Intron Biotechnology Inc
Priority to US16/464,872 priority Critical patent/US11213050B2/en
Publication of WO2018101595A2 publication Critical patent/WO2018101595A2/ko
Publication of WO2018101595A3 publication Critical patent/WO2018101595A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/40—Viruses, e.g. bacteriophages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
    • A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
    • A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
    • A23K30/18—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging using microorganisms or enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10331—Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)

Abstract

본 발명은 대장균을 특이적으로 사멸시킬 수 있는 능력을 갖고 서열번호 1로 표시되는 유전체를 갖는 것을 특징으로 하는 자연으로부터 분리된 미오비리대 박테리오파지 Esc-COP-9(수탁번호 KCTC 13131BP), 및 이를 유효성분으로 포함하는 조성물을 이용한 병원성 대장균의 감염을 방지 및 치료하는 방법에 관한 것이다.
PCT/KR2017/010957 2016-11-30 2017-09-29 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도 Ceased WO2018101595A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US16/464,872 US11213050B2 (en) 2016-11-30 2017-09-29 Escherichia coli bacteriophage Esc-COP-9 and use for inhibiting proliferation of pathogenic Escherichia coli thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0161324 2016-11-30
KR1020160161324A KR101796642B1 (ko) 2016-11-30 2016-11-30 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도

Publications (2)

Publication Number Publication Date
WO2018101595A2 WO2018101595A2 (ko) 2018-06-07
WO2018101595A3 true WO2018101595A3 (ko) 2018-08-09

Family

ID=60386504

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/010957 Ceased WO2018101595A2 (ko) 2016-11-30 2017-09-29 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도

Country Status (3)

Country Link
US (1) US11213050B2 (ko)
KR (1) KR101796642B1 (ko)
WO (1) WO2018101595A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11058131B2 (en) 2015-04-16 2021-07-13 Kennesaw State University Research And Service Foundation, Inc. Escherichia coli O157:H7 bacteriophage Φ241
KR102064765B1 (ko) 2018-02-02 2020-01-15 경북대학교 산학협력단 병원성 대장균의 증식을 억제하는 신규 박테리오파지 및 이의 용도

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110041670A (ko) * 2009-10-16 2011-04-22 경희대학교 산학협력단 대장균 또는 시겔라속 균에 특이적 사멸능을 갖는 박테리오파지
WO2016108541A1 (ko) * 2014-12-30 2016-07-07 주식회사 인트론바이오테크놀로지 신규한 시가독소생산 F18형 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-1 및 이의 시가독소생산 F18형 대장균 증식 억제 용도
KR20160080575A (ko) * 2014-12-30 2016-07-08 주식회사 인트론바이오테크놀로지 신규한 장병원성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-2 및 이의 장병원성 대장균 증식 억제 용도

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110041670A (ko) * 2009-10-16 2011-04-22 경희대학교 산학협력단 대장균 또는 시겔라속 균에 특이적 사멸능을 갖는 박테리오파지
WO2016108541A1 (ko) * 2014-12-30 2016-07-07 주식회사 인트론바이오테크놀로지 신규한 시가독소생산 F18형 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-1 및 이의 시가독소생산 F18형 대장균 증식 억제 용도
KR20160080575A (ko) * 2014-12-30 2016-07-08 주식회사 인트론바이오테크놀로지 신규한 장병원성 대장균 박테리오파지 Ｅｓｃ-ＣＨＰ-2 및 이의 장병원성 대장균 증식 억제 용도

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE Nucleotide [O] 13 December 2013 (2013-12-13), XP055534472, retrieved from NCBI Database accession no. KC710998.1 *
JUN, JIN WOO ET AL.: "Characterization and Complete Genome Sequence of the Shigella Bacteriophage pSf-1", RESEARCH IN MICROBIOLOGY, vol. 164, no. 10, December 2013 (2013-12-01), pages 979 - 986, XP002781587 *

Also Published As

Publication number Publication date
KR101796642B1 (ko) 2017-11-10
US11213050B2 (en) 2022-01-04
WO2018101595A2 (ko) 2018-06-07
US20190321423A1 (en) 2019-10-24

Similar Documents

Publication Publication Date Title
MX384834B (es) Novedoso bacteriófago esc-cop-1 de e. coli tipo f18 productora de toxina shiga y su uso para inhibir la proliferación de e. coli tipo f18 productora de toxina shiga
WO2020160193A3 (en) Compounds and uses thereof
MX383530B (es) Novedoso bacteriófago de e. coli enteroinvasiva esc-cop-4 y su uso para inhibir la proliferación de e. coli enteroinvasiva
EP4360651A3 (en) Glp-1 compositions and uses thereof
BR112018012044A2 (pt) bacteriófago pas-mup-1 de pasteurella multocida inovador e uso do mesmo para inibir a proliferação de pasteurella multocida
MX383531B (es) Novedoso bacteriófago clo-pep-1 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens
EP4356969A3 (en) Fused tricyclic pyridazinone compounds useful to treat orthomyxovirus infections
CO2019010062A2 (es) Novedoso bacteriófago clo-pep-2 de clostridium perfringens y su uso para inhibir la proliferación de clostridium perfringens
MX2020006191A (es) Bacteriocinas terapeuticas.
WO2018155813A3 (ko) 엔테로코쿠스 패슘에 대하여 용균력을 가지는 신규한 항균단백질 efal-2
PH12016502003A1 (en) Novel bacteriophage and composition containing same
PH12016501999B1 (en) Novel bacteriophage and composition containing same
PH12016502001B1 (en) Novel bacteriophage and composition comprising same
WO2019235782A8 (ko) 신규한 스트렙토코커스 수이스 박테리오파지 str-sup-2 및 이의 스트렙토코커스 수이스 균 증식 억제 용도
WO2018101595A3 (ko) 대장균 박테리오파지 Ｅｓｃ-ＣＯＰ-9 및 이의 병원성 대장균 증식 억제 용도
WO2011155727A3 (ko) 살모넬라 콜레라수이스 또는 살모넬라 두블린 감염을 방지 및 처치하는 방법
GB2568440A (en) Modified factor H binding protein
WO2019235783A8 (ko) 신규한 스트렙토코커스 수이스 박테리오파지 str-sup-3 및 이의 스트렙토코커스 수이스 균 증식 억제 용도
WO2018117462A3 (ko) 신규한 비브리오 파라헤몰리티쿠스 박테리오파지 Ｖｉｂ-ＰＡＰ-4 및 이의 비브리오 파라헤몰리티쿠스 균 증식 억제 용도
EP4467198A3 (en) Fused tricyclic pyridazinone compounds and prodrugs thereof useful to treat orthomyxovirus infections
WO2019039781A3 (ko) 신규한 에로모나스 살모니시다 박테리오파지 ａｅｒ-ｓａｐ-2 및 이의 에로모나스 살모니시다 균 증식 억제 용도
MX2020008677A (es) Novedoso bacteriofago de salmonella heidelberg sal-hep-1 y su uso para inhibir el crecimiento de las bacterias de salmonella heidelberg.
WO2018236086A3 (ko) 신규한 에로모나스 하이드로필라 박테리오파지 Aer-HYP-2 및 이의 에로모나스 하이드로필라 균 증식 억제 용도
PH12016502000A1 (en) Novel bacteriophage and composition comprising same
MY191843A (en) Trehalose phosphorylase

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17877009

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17877009

Country of ref document: EP

Kind code of ref document: A2