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WO2018193955A1 - Système de test de fonction de déglutition utilisant une caméra 3d - Google Patents

Système de test de fonction de déglutition utilisant une caméra 3d Download PDF

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Publication number
WO2018193955A1
WO2018193955A1 PCT/JP2018/015342 JP2018015342W WO2018193955A1 WO 2018193955 A1 WO2018193955 A1 WO 2018193955A1 JP 2018015342 W JP2018015342 W JP 2018015342W WO 2018193955 A1 WO2018193955 A1 WO 2018193955A1
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WO
WIPO (PCT)
Prior art keywords
swallowing
data
dynamics
body surface
timing information
Prior art date
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Ceased
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PCT/JP2018/015342
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English (en)
Japanese (ja)
Inventor
佐藤　秀夫
祐士 山本
洋一朗 岩下
要一 山▲崎▼
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Kagoshima University NUC
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Kagoshima University NUC
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Filing date
Publication date
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Priority to JP2019513590A priority Critical patent/JP6952365B2/ja
Publication of WO2018193955A1 publication Critical patent/WO2018193955A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb

Definitions

  • the present invention relates to a swallowing function test system using a 3D camera.
  • swallowing function a characteristic seen in the elderly is a decrease in swallowing function (hereinafter referred to as “swallowing function”). Decreased swallowing function causes aspiration and suffocation, as well as aspiration pneumonia. Therefore, diagnosing swallowing function is important for the elderly.
  • the swallowing function can be invasively performed with a C-arm fluoroscope (VF) or a swallowing endoscope (VE, for home visit). It is common to inspect.
  • VF C-arm fluoroscope
  • VE swallowing endoscope
  • body surface dynamics body surface dynamics
  • the present invention has been made in view of the above circumstances, and provides a swallowing function test system, a swallowing function analysis method, and a program that can test the swallowing function of a subject inexpensively, simply, non-invasively and accurately.
  • the purpose is to provide.
  • a swallowing function test system includes: A timing information generator for generating timing information;
  • the body surface dynamics acquisition unit that acquires the body surface dynamics data that operates along with the swallowing operation of the subject in the period when the swallowing operation is performed, including the time point when the timing information is generated in the timing information generating unit,
  • An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including the time when the timing information is generated in the timing information generation unit; Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data
  • a generator Based on the synchronization data, an analysis unit that analyzes the correlation between the body surface dynamics and internal dynamics of the subject during the swallowing operation; Is provided.
  • the analysis unit Estimating the state of swallowing function of the subject based on the body surface dynamics data obtained by imaging again the body surface dynamics during the swallowing motion in the same subject, and the synchronization data, It is good as well.
  • the analysis unit Analyzing the state of the swallowing function of the subject based on items related to the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamics data, It is good as well.
  • the synchronous data generation unit For each subject, generate the synchronization data, The analysis unit Using the synchronization data for each subject, analyze the swallowing function of the subject corresponding to the synchronization data, It is good as well.
  • the timing information generating unit generates a sound as the timing information. It is good as well.
  • the program according to the third aspect of the present invention is: Computer A timing information generator for generating timing information; A body surface dynamics acquisition unit for acquiring body surface dynamics data that operates in accordance with the swallowing motion of the subject in a period in which the swallowing motion is performed, including the time when the timing information is generated in the timing information generator; An internal dynamics acquisition unit that acquires internal dynamics data of the same subject that operates along with the swallowing operation in a period during which the swallowing operation is performed, including a time point when the timing information is generated in the timing information generation unit; Synchronous data for generating synchronization data of internal dynamics and body surface dynamics during the swallowing operation by combining the time when timing information is generated with the body surface dynamics data and the time when timing information is generated with the internal dynamics data Generator, Based on the synchronization data, an analysis unit that analyzes the correlation between body surface dynamics and internal dynamics of the subject during the swallowing operation, To function as.
  • the body surface dynamics and the internal dynamics of the subject during the swallowing operation are generated. Can be analyzed. For this reason, the swallowing function of the subject can be examined inexpensively, simply, noninvasively and accurately from the body surface dynamics.
  • FIG. 1 It is a schematic diagram which shows the whole environment where the swallowing function test
  • (A) And (B) is a schematic diagram which shows a mode that synchronous data are produced
  • FIG. 1 shows the entire environment in which the swallowing function test system 1 according to the present embodiment is used.
  • the swallowing function test system 1 is a system for causing a subject P to swallow a sample and testing the swallowing function.
  • the swallowing function test system 1 is communicably connected to various facilities installed in the test room 2.
  • a speaker 3 In the examination room 2, a speaker 3, a three-dimensional shape measuring device 4, and a contrast examination device 5 are installed as such facilities.
  • Speaker 3 generates a sound (buzzer) as timing information. This sound becomes a trigger when performing various operations such as the swallowing operation of the subject P. This sound is also used for generating synchronization data, as will be described later.
  • Kinect registered trademark
  • Kinect is available as such a three-dimensional shape measuring apparatus 4.
  • Kinect records the three-dimensional position coordinates of each measurement point in real time every 1/30 seconds.
  • Kinect registered trademark
  • Kinect is advantageous in that it is small, portable, low-cost, and a software program for calculating a three-dimensional shape is open sourced.
  • the three-dimensional shape measuring apparatus 4 captures three-dimensional images of the object and records surrounding sounds using a multi-array microphone.
  • the contrast examination (Video Fluorography) apparatus 5 is an X-ray imaging apparatus that captures a fluoroscopic image of the jaw portion of the subject P. As shown in FIG. 5, the imaging direction is the lateral direction of the subject P.
  • the contrast examination apparatus 5 starts imaging the jaw portion of the subject P according to an instruction from the outside, and ends imaging according to the instruction from the outside. From this imaging result, it is possible to observe the internal dynamics of the oral cavity, pharynx, and esophagus that operate with the swallowing operation when the subject P performs the swallowing operation.
  • the contrast inspection apparatus 5 captures a fluoroscopic image of the object and records surrounding sounds.
  • the swallowing function test system 1 includes a timing information generation unit 10, a body surface dynamics acquisition unit 11, an internal dynamics acquisition unit 12, a synchronization data generation unit 13, and an analysis unit 14.
  • the timing information generator 10 causes the speaker 3 to generate sound as timing information.
  • the sound to be generated is an electronic sound such as a buzzer, but is not limited to this.
  • the sound to be generated may be a human voice.
  • the body surface dynamics acquisition unit 11 acquires body surface dynamics data related to the swallowing motion of the subject P.
  • the acquired body surface dynamics data includes time points T1 and T2 when the timing information is generated by the timing information generator 10 (see, for example, FIG. 4), and is time-series data including a period during which the swallowing operation is performed. .
  • the three-dimensional shape measuring device 4 picks up the subject P, records an electronic sound, and measures the three-dimensional shape. To start. Further, when the body surface dynamics acquisition unit 11 instructs the 3D shape measurement device 4 to end the measurement, the 3D shape measurement device 4 ends the imaging of the subject P, the recording of the electronic sound, and the measurement of the 3D shape. . Video data, electronic sound data, and a measurement result of the three-dimensional shape captured by the three-dimensional shape measurement apparatus 4 are transmitted to the body surface dynamics acquisition unit 11.
  • the body surface dynamics acquisition unit 11 includes a body surface dynamics information generation unit 11A and a storage unit 11B as shown in FIG.
  • the body surface dynamics information generation unit 11A stores the video and electronic sound data received from the three-dimensional shape measurement apparatus 4 in the storage unit 11B. This data is referred to as video and electronic sound data 11C. Furthermore, the body surface dynamics information generation unit 11A generates body surface dynamics data 11D based on the received measurement result of the three-dimensional shape and stores it in the storage unit 11B.
  • the internal kinetic acquisition unit 12 acquires internal kinetic data 12D in the oral cavity, pharynx, and esophagus of the same subject P during the period in which the swallowing operation is performed.
  • the internal dynamic data 12 ⁇ / b> D includes time points T ⁇ b> 1 and T ⁇ b> 2 when an electronic sound is generated by the timing information generation unit 10, and indicates a temporal change of a fluoroscopic image obtained by moving the jaw portion of the subject P from the side. Time series data. From this data, it is possible to observe the swallowing process from the oral phase to the pharyngeal phase to the esophageal phase.
  • the acquired internal behavior data 12 ⁇ / b> D is data for a period including time points T ⁇ b> 1 and T ⁇ b> 2 when an electronic sound is generated in the timing information generation unit 10.
  • the internal dynamic acquisition unit 12 acquires the internal dynamic data 12D and simultaneously records the electronic sound data 12C.
  • the contrast inspection apparatus 5 When the internal dynamic acquisition unit 12 instructs the contrast inspection apparatus 5 to start imaging, the contrast inspection apparatus 5 starts imaging and recording of fluoroscopic imaging of the subject P, and the internal dynamic acquisition unit 12 When instructing the end of the measurement of the fluoroscopic image of the face of the examiner P, the contrast inspection device 5 ends the imaging and recording of the fluoroscopic image of the face of the examinee P.
  • the internal dynamic data 12D and the electronic sound data 12C imaged by the contrast inspection apparatus 5 are transmitted to the internal dynamic acquisition unit 12.
  • the internal dynamic data 12D and the electronic sound data 12C are stored in the internal dynamic acquisition unit 12.
  • the synchronization data generation unit 13 generates synchronization data of internal dynamics and body surface dynamics during the swallowing motion.
  • the synchronization data is performed by combining the time points T1 and T2 when the timing information is generated in the body surface dynamic data 11D and the time points T1 and T2 when the timing information is generated in the internal dynamic data 12D.
  • FIG. 8 shows an example of a screen on which body surface dynamics and internal dynamics are simultaneously displayed based on the synchronization data 7.
  • Internal dynamic data 12D is shown on the upper left of the screen, and body surface dynamic data 11D is shown on the right.
  • time series data of the inter-oral distance L which is a part of the body surface dynamic data 11D is shown at the lower side of the screen.
  • the analysis unit 14 reads the synchronization data 7 from the synchronization data generation unit 13 and analyzes it. Specifically, the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics during the swallowing operation. The analysis of the correlation is performed, for example, by analyzing the state of the swallowing function of the subject P based on the item regarding the dynamics of a specific part on the body surface during the swallowing operation obtained from the body surface dynamic data 11D. Is called.
  • the specific part includes information regarding the inter-oral distance L. In this case, for example, the distance L between mouth corners at rest, the distance L between mouth angles before the start of swallowing, the amount of displacement of the distance L between mouth corners of the swallowing operation, the swallowing time, and the like can be set as measurement items.
  • FIG. 9 shows a hardware configuration of the swallowing function test system 1 of FIG.
  • the swallowing function test system 1 includes a control unit 31, a main storage unit 32, an external storage unit 33, an operation unit 34, a display unit 35, and a communication unit 36.
  • the main storage unit 32, the external storage unit 33, the operation unit 34, and the display unit 35 are all connected to the control unit 31 through the internal bus 30.
  • the main storage unit 32 is composed of RAM (Random-Access Memory) or the like.
  • the main storage unit 32 is loaded with a program 39 stored in the external storage unit 33.
  • the main storage unit 32 is used as a work area (temporary data storage area) of the control unit 31.
  • the external storage unit 33 includes a non-volatile memory such as a flash memory, a hard disk, a DVD-RAM (Digital Versatile Disc Random-Access Memory), a DVD-RW (Digital Versatile Disc ReWritable).
  • a program 39 to be executed by the control unit 31 is stored in advance. Further, the external storage unit 33 supplies data used when executing the program 39 to the control unit 31 in accordance with an instruction from the control unit 31, and stores the data supplied from the control unit 31.
  • the operation unit 34 includes a pointing device such as a keyboard and a mouse, and an interface device that connects the keyboard and the pointing device to the internal bus 30. Information regarding the content operated by the operator is input to the control unit 31 via the operation unit 34.
  • the communication unit 36 is a communication interface with an external device.
  • the speaker 3, the three-dimensional shape measuring device 4, and the contrast examination device 5 are connected to be communicable via the communication unit 36.
  • the body surface dynamics acquisition unit 11 includes time points T1 and T2 when electronic sounds are generated, and the body fluctuates with the swallowing motion of the subject P during the swallowing motion.
  • the internal dynamic acquisition unit 12 changes the internal dynamic data 12D of the subject P that fluctuates with the swallowing operation in the period during which the swallowing operation is performed ( Electronic sound data 12C) is acquired (step S1: dynamic acquisition step).
  • the dynamic acquisition step is performed according to the procedure shown in FIG. This procedure is performed under the control of the swallowing function test system 1.
  • the subject P is made to wait at the measurement position.
  • Shooting by the three-dimensional shape measuring apparatus 4 is started.
  • VF imaging by the contrast inspection apparatus 5 is started and a timer is started. 4).
  • a sample (for example, water) is taken in by the first electronic sound generated at time T1. 5).
  • the sample is swallowed by the second electronic sound generated at time T2. 6).
  • the subject P raises his hand, and at that point the imaging is terminated and the measurement is terminated.
  • body surface dynamic data 11D and internal dynamic data 12D are acquired.
  • the synchronization data generation unit 13 combines the timing (T1, T2) when the electronic sound is generated with the body surface dynamic data 11D and the timing (T1, T2) when the electronic sound is generated with the internal dynamic data 12D, Synchronous data 7 between the internal dynamic data 12D and the body surface dynamic data 11D during the swallowing operation is generated (step S2; synchronous data generating step).
  • the analysis unit 14 analyzes the correlation between the body surface dynamics and the internal dynamics of the subject P during the swallowing operation based on the synchronization data 7 (step S3; analysis process).
  • FIG. 12A shows the internal dynamics obtained when a subject P1 swallows 5 ml of water
  • FIG. 12B shows the state of fluctuation of the inter-angular distance L as the body surface dynamics at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is minimized
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • Time t4 is the time when the subject P1 raised his hand.
  • FIG. 13A shows the internal dynamics acquired when another subject P2 swallows 5 ml of water
  • FIG. 13B shows how the inter-oral distance L changes at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the distance L between the mouth corners is minimized
  • the time point t5 is a time point when the subject P2 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, and then contracted to finish swallowing and then returned to the normal length.
  • FIG. 14A shows the internal dynamics obtained when another subject P1 swallows 15 ml of water
  • FIG. 14B shows how the inter-oral distance L fluctuates at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the interoral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the inter-angular distance L is minimized
  • the time point t5 is a time point when the subject P1 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
  • FIG. 15A shows the internal dynamics acquired when another subject P2 swallows 15 ml of water
  • FIG. 15B shows the fluctuation of the inter-oral distance L at that time.
  • the time point t1 is a time point immediately after the swallowing instruction
  • the time point t2 is the time point when the inter-oral distance L is maximum
  • the time point t3 is a time point when the water passes through the fourth cervical vertebra and the swallowing is finished. is there.
  • the time point t4 is a time point when the distance L between the mouth corners is minimized
  • the time point t5 is a time point when the subject P2 raises his hand.
  • the inter-oral distance L was stretched immediately after the swallowing instruction, then contracted and finished swallowing, and then returned to the normal length.
  • the synchronization data generating unit 13 generates the synchronization data 7 for each subject P. It is desirable that the analyzing unit 14 uses the synchronization data 7 for each subject P and analyzes the swallowing function of the subject P based on the synchronization data 7.
  • the analysis unit 14 includes a storage unit 14C, and the synchronization data 7A of the subject PA, the synchronization data 7B of the subject PB, and the synchronization data 7C of the subject PC are stored in the storage unit 14C. An example is shown.
  • the analysis unit 14 is based on the body surface dynamics data 11D acquired by imaging the body surface dynamics during the swallowing motion in the subjects PA to PC, and the synchronization data 7A to 7C.
  • the state of the swallowing function of the subjects PA to PC may be estimated. It is assumed that the swallowing function test system 1 is connected to a three-dimensional shape measuring device 4 installed in a home 8 of the subject PA, PB, or PC via a communication network 9.
  • the body surface dynamics data 11D of the subject PA is acquired by the three-dimensional shape measuring apparatus 4 installed in the home 8 of the subject PA, the data is transferred to the swallowing function test system 1 via the communication network 9. Sent to.
  • the analysis unit 14 of the swallowing function test system 1 estimates the current swallowing function state of the subject PA based on the body surface dynamics data 11D of the subject PA. For example, when the variation pattern of the inter-oral distance L obtained from the received body surface dynamics data 11D and the variation pattern of the easy-to-mouth distance L stored as the synchronization data 7A become large (for example, when the swallowing time is long or intense If it fluctuates), it is estimated that there is a possibility that a dysphagia has occurred in the subject PA. If such an estimation result is obtained, a more accurate diagnosis can be performed on the subject PA. The same applies to the subjects PB and PC. If such a mechanism is constructed, home medical care can be performed, and the burden on the subject P or the like is remarkably reduced.
  • the synchronization data 7 between the body surface dynamics data 11D and the internal dynamics data 12D of the subject P during the swallowing operation is generated.
  • the state of the swallowing function of the subject P can be estimated simply by measuring the body surface dynamics of the subject P. For this reason, the swallowing function of the subject P can be examined inexpensively, simply, noninvasively and accurately.
  • the body surface dynamic data 11D and the internal dynamic data 12D are synchronized at the timing of the time points T1 and T2.
  • the data 11D and 12D may be synchronized only at the time point T2.
  • the sample swallowed by the subject P is water, but the present invention is not limited to this. Other beverages may be used.
  • the hardware configuration and software configuration of the swallowing function test system 1 are examples, and can be arbitrarily changed and modified.
  • the function of the swallowing function test system 1 is realized by sharing an OS (operating system) and an application program, or in cooperation with the OS and the application program, only the application program part is stored in a recording medium or a storage device. May be.
  • a computer program may be posted on a bulletin board (BBS, “Bulletin“ Board System ”) on a communication network, and the computer program distributed via the network.
  • the computer program may be started and executed in the same manner as other application programs under the control of the OS, so that the above-described processing may be executed.
  • the present invention can be applied to the examination of swallowing function. In particular, it can be applied when diagnosing the swallowing function in home medical care.

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Abstract

Dans la présente invention, une unité d'acquisition de mouvement de surface corporelle (11) acquiert des données de mouvement de surface corporelle qui comprennent le temps auquel des informations de temporisation sont générées par une unité de génération d'informations de temporisation (10) qui fonctionne en conséquence de l'action de déglutition d'un sujet pendant une période dans laquelle l'action de déglutition est effectuée. Une unité d'acquisition de mouvement interne (12) acquiert des données de mouvement interne du même sujet qui comprennent le temps auquel des informations de temporisation sont générées par l'unité de génération d'informations de synchronisation (10) et fonctionne en conséquence de l'action de déglutition du sujet pendant la période dans laquelle l'action de déglutition est effectuée. Une unité de génération de données synchronisées (13) synchronise la temporisation à laquelle les informations de temporisation ont été générées dans les données de mouvement de surface corporelle et la temporisation à laquelle les informations de temporisation ont été générées dans les données de mouvement interne, et génère ainsi des données synchronisées du mouvement interne et du mouvement de surface corporelle pendant l'action de déglutition. Une unité d'analyse (14) analyse la corrélation entre le mouvement de surface corporelle et le mouvement interne pendant l'action de déglutition sur la base des données synchronisées.
PCT/JP2018/015342 2017-04-18 2018-04-12 Système de test de fonction de déglutition utilisant une caméra 3d Ceased WO2018193955A1 (fr)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021044592A1 (fr) * 2019-09-05 2021-03-11 株式会社タニタ Dispositif d'évaluation de fonction de déglutition
CN113329683A (zh) * 2019-02-13 2021-08-31 雀巢产品有限公司 用于筛查吞咽受损的方法和装置
JP2022048411A (ja) * 2020-09-15 2022-03-28 コニカミノルタ株式会社 Ｘ線動態画像表示装置、プログラム、ｘ線動態画像表示方法及びｘ線動態画像表示システム
EP4091528A1 (fr) 2021-05-21 2022-11-23 FUJI-FILM Corporation Système d'endoscope et son procédé de fonctionnement

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JP2013031650A (ja) * 2011-06-30 2013-02-14 Gifu Univ 摂食運動測定システムおよび測定方法
WO2016006633A1 (fr) * 2014-07-10 2016-01-14 国立大学法人 鹿児島大学 Dispositif de diagnostic, système de diagnostic, procédé de simulation et programme

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113329683A (zh) * 2019-02-13 2021-08-31 雀巢产品有限公司 用于筛查吞咽受损的方法和装置
JP2022521172A (ja) * 2019-02-13 2022-04-06 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 嚥下障害をスクリーニングする方法及びデバイス
WO2021044592A1 (fr) * 2019-09-05 2021-03-11 株式会社タニタ Dispositif d'évaluation de fonction de déglutition
JP2022048411A (ja) * 2020-09-15 2022-03-28 コニカミノルタ株式会社 Ｘ線動態画像表示装置、プログラム、ｘ線動態画像表示方法及びｘ線動態画像表示システム
JP7463923B2 (ja) 2020-09-15 2024-04-09 コニカミノルタ株式会社 Ｘ線動態画像表示装置、プログラム、ｘ線動態画像表示方法及びｘ線動態画像表示システム
EP4091528A1 (fr) 2021-05-21 2022-11-23 FUJI-FILM Corporation Système d'endoscope et son procédé de fonctionnement

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