WO2018180009A1 - Fullerene-containing cosmetic composition - Google Patents

Abstract

Provided is a cosmetic composition that facilitates dispersion of fullerene in water. Also provided is a cosmetic composition which is used to prepare a fullerene-containing aqueous dispersion having a transluscent appearance and excellent dispersion stability. A cosmetic composition containing (A) an oil agent containing 0.001-0.3% of fullerene dissolved therein, (B) a nonionic surfactant, (C) a polyvalent alcohol, (D) an oil agent, and (E) water is used. The composition preferably has a bicontinuous structure.

Description

Fullerene-containing cosmetic composition

The present invention relates to a cosmetic composition containing fullerene, and a cosmetic using the cosmetic composition.

In recent years, attempts have been made to use fullerenes in cosmetics, and the trend has become even stronger, especially after fullerene's ability to scavenge active oxygen. In addition to the active oxygen scavenging ability, there are various application examples of fullerenes for cosmetics, for example, application as a pigment (Patent Document 1), application as an ultraviolet absorber (Patent Document 2), application as a melanin inhibitor (Patent) Document 3), application as a wrinkle inhibitor (Patent Document 4), application as a hair damage inhibitor (Patent Document 5), and the like are known.

On the other hand, fullerene is a poorly soluble substance, and particularly insoluble in water. Therefore, it is very difficult to add it to an aqueous formulation as it is. As a method for solving such a problem, for example, a method in which a water-soluble polymer such as polyvinylpyrrolidone is combined and dispersed in water is known (Patent Document 6). However, in this method, there is a case where an unpleasant feel of the water-soluble polymer to be used is produced, and there is a problem that the effect of fullerene is not sufficiently exhibited depending on applications. As another method, a method of encapsulating in a liposome using phospholipid and dispersing in water (Patent Document 7) is known. However, since preparation of liposomes requires complicated steps, it has not been a simple method for preparing an aqueous dispersion of fullerene. As another method, there is known a method in which fullerene is once dissolved in hydrocarbon oil and then emulsified using a surfactant (Patent Document 8). However, even in such a method, the preparation is not necessarily simple, and the obtained aqueous dispersion has poor transparency and the dispersion stability is not sufficient.

Japanese Patent Laid-Open No. 06-192039 JP 09-278625 A JP 2007-131536 A International Publication No. 2009/113426 JP 2016-169215 A JP 2005-060380 A JP 2009-242380 A JP 2008-255107 A

The subject of this invention is providing the composition for cosmetics which can disperse fullerene easily in water.
Another object of the present invention is to provide a cosmetic composition with a fullerene-containing aqueous dispersion prepared using the composition having a transparent appearance and excellent dispersion stability.

As a result of intensive studies to solve the above problems, the present inventors can easily disperse fullerenes in water by using a cosmetic composition containing the following components (A) to (E). The present invention has been completed by finding that the above-mentioned problems can be solved.
(A) Oil agent in which 0.001 to 0.3% by weight of fullerene is dissolved (B) Nonionic surfactant (C) Polyhydric alcohol (D) Oil agent (E) Water Further, the cosmetic composition is bi-continue. It has been found that the fullerene-containing aqueous dispersion prepared by using the composition has a transparent appearance and is excellent in dispersion stability because of having a nuus structure and solves the above problems. The present invention has been completed.

By using the cosmetic composition of the present invention, fullerene can be easily dispersed in water.
Further, since the cosmetic composition has a bicontinuous structure, the resulting aqueous dispersion has a transparent appearance and its dispersion stability is very good.

In Example 51, it is a graph which shows the relationship between the frequency | count of damage after hair dyeing, and measured (DELTA) E. It is a graph which shows the result of having quantified the quantity of the cysteic acid in the hair produced by an ultraviolet-ray about the cosmetic composition of Example 1. FIG.

The cosmetic composition of the present invention contains the following components (A) to (E) as essential components.
(A) Oil agent in which 0.001 to 0.3% by weight of fullerene is dissolved (B) Nonionic surfactant (C) Polyhydric alcohol (D) Oil agent (E) Water

The component (A) used in the present invention means an oil agent in which fullerene is dissolved at a concentration of 0.001 to 0.3% by weight relative to the oil agent. 01 to 0.28% by weight, most preferably 0.03 to 0.25% by weight. There is no particular limitation on the method for dissolving fullerene in the oil, and the oil and fullerene can be prepared by heating and dissolving with stirring. Alternatively, it can be prepared by a method as described in JP 2011-256095 A in order to dissolve fullerene at a higher concentration. Specifically, it can be prepared by first dissolving fullerene in a solvent such as toluene or cyclohexane, then adding an oil agent so that the fullerene has a predetermined concentration, and distilling off the solvent under reduced pressure.

The fullerene used in the component (A) of the present invention is a general term for a spherical shell molecule composed of carbon atoms, and the carbon number thereof is C ₆₀ , C ₇₀ , C ₇₆ , C ₇₈ , C ₈₂ , C ₈₄ , C ₉₀ and C ₉₆ are known. Any of such fullerenes can be used in the present invention. These fullerenes may be used alone or in combination of two or more. Among these, from the viewpoint of solubility and availability of easy to oil, C _{60, C 70,} and, it is preferable to use a mixture thereof.

The oil agent used in the component (A) of the present invention is not particularly limited as long as it is an oil agent that dissolves fullerene. Specifically, lactone derivatives, ester oils, vegetable oils, hydrocarbon oils, and the like can be used. May be used alone or in admixture of two or more. Of these, lactone derivatives and ester oils are preferred from the viewpoint of dissolving fullerene stably and at a high concentration, and it is most preferred to use both.

（式中、ｎは１又は２であり、Ｒは炭素数９～２２の直鎖又は分岐鎖の飽和又は不飽和炭化水素基を表す）
　上記一般式（１）中のＲとしては、具体的には、ノニル基、デシル基、ウンデシル基、ドデシル基、トリデシル基、テトラデシル基、ペンタデシル基、ヘキサデシル基、ヘプタデシル基、オクタデシル基、ノナデシル基、エイコシル基、ヘンイコシル基、ドコシル基等が挙げられ、これらのうち、原料の入手しやすさ、合成のしやすさなどの面から、デシル基、ウンデシル基、ドデシル基、トリデシル基、テトラデシル基、ペンタデシル基、ヘキサデシル基、ヘプタデシル基、オクタデシル基、エイコシル基、ヘンイコシル基がより好ましく、デシル基、ドデシル基、テトラデシル基、オクタデシル基が最も好ましい。また、式中のｎとしては１の化合物が好ましい。このようなラクトン誘導体の最も好ましいものとしては、γ－テトラデカラクトン、γ－ヘキサデカラクトン、γ－オクタデカラクトン、γ－イコサラクトン、γ－ドコサラクトン等が挙げられる。 More specifically, the lactone derivative used in the component (A) includes a compound represented by the following general formula (1).

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)
As R in the general formula (1), specifically, nonyl group, decyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, nonadecyl group, Eicosyl group, heicosyl group, docosyl group, etc. are mentioned. Of these, decyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, etc. from the viewpoints of availability of raw materials and ease of synthesis. Group, hexadecyl group, heptadecyl group, octadecyl group, eicosyl group and heneicosyl group are more preferable, and decyl group, dodecyl group, tetradecyl group and octadecyl group are most preferable. In the formula, n is preferably 1 compound. The most preferred examples of such lactone derivatives include γ-tetradecalactone, γ-hexadecalactone, γ-octadecalactone, γ-icosalactone, and γ-docosalactone.

The ester oil used in component (A) is more specifically described: glyceryl triethylhexanoate, glyceryl tricaprylate, glyceryl tricaprate, glyceryl tri (caprylate / caprate), glyceryl trioleate, triisostearic acid Glyceryl, trimethylolpropane triethylhexanoate, pentaerythrityl tetraethylhexanoate, 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl-1,5-pentanediol dineopentanoate, cetyl ethylhexanoate, ethyl Hexyldecyl hexanoate, isononyl isononanoate, isodecyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate Octyldodecyl neodecanoate, isopropyl myristate, hexyldecyl myristate, octyldodecyl myristate, isopropyl palmitate, ethylhexyl palmitate, cetyl palmitate, octyldodecyl palmitate, ethyl oleate, oleyl oleate, octyldodecyl oleate, isostearic acid Isopropyl, octyldodecyl isostearate, octyldodecyl erucate, lanolin fatty acid isopropyl, lanolin fatty acid octyldodecyl, dicaprylyl carbonate, diethylhexyl succinate, diisopropyl adipate, diisobutyl adipate, diethyl sebacate, diisopropyl sebacate, diethylhexyl sebacate , Triethyl citrate, diisostearyl malate and the like. Among these, glyceryl triethylhexanoate, glyceryl tri (caprylic acid / capric acid), cetyl ethylhexanoate, ethylhexyl palmitate, diethylhexyl sebacate are preferred, and tri (caprylic acid / capric acid) glyceryl, ethyl Most preferred is cetyl hexanoate.

Examples of the nonionic surfactant of component (B) used in the present invention include polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene fatty acid ester, and polyoxyethylene alkyl ether. One or two or more selected can be used. These may be used singly or in combination of two or more.

Specific examples of the polyglycerin fatty acid ester include monoesters, diesters, triesters, tetraesters, etc., of fatty acids having 8 to 22 carbon atoms and polyglycerin having a polymerization degree of 2 to 20. Among these, preferred are polyglyceryl caprylate, polyglyceryl caprate, polyglyceryl laurate, polyglyceryl myristate, polyglyceryl palmitate, polyglyceryl stearate, polyglyceryl isoleate, polyglyceryl isostearate, polyglyceryl behenate, polyglyceryl dicaprylate, diglyceryl polyglyceryl , Polyglyceryl dilaurate, polyglyceryl dimyristate, polyglyceryl dipalmitate, polyglyceryl distearate, polyglyceryl diistearate, polyglyceryl diisostearate, polyglyceryl dibehenate, polyglyceryl tricaprylate, polyglyceryl tricaprate, polyglyceryl trilaurate, polyglyceryl trilaurate Examples include polyglyceryl tinate, polyglyceryl tristearate, polyglyceryl trioleate, polyglyceryl triisostearate, polyglyceryl tribehenate, polyglyceryl laurate, polyglyceryl stearate, polyglyceryl isostearate, polyglyceryl dilaurate, polyglyceryl distearate, polyglyceryl diisostearate Is most preferred.

Specific examples of the polyoxyethylene glycerin fatty acid ester include monoesters and diesters of glycerin polyoxyethylene adducts having an addition mole number of polyoxyethylene (EO) of 4 to 200 and fatty acids of 8 to 22 carbon atoms, Examples include triesters. Among these, caprylic acid polyoxyethylene glycerin, capric acid polyoxyethylene glycerin, lauric acid polyoxyethylene glycerin, myristic acid polyoxyethylene glycerin, palmitic acid polyoxyethylene glycerin, stearic acid polyoxyethylene glycerin, olein Acid polyoxyethylene glycerin, polyisoethylene glyceryl isostearate, polyoxyethylene glycerin dicaprylate, polyoxyethylene glycerin dicaprate, polyoxyethylene glyceryl dilaurate, polyoxyethylene glycerin dimyristate, polyoxyethylene glycerine dipalmitate, Polyoxyethylene glyceryl distearate, polyoxyethylene glycerin dioleate, dii Polyoxyethylene glyceryl stearate, polyoxyethylene glyceryl tricaprylate, polyoxyethylene glyceryl tricaprate, polyoxyethylene glyceryl trilaurate, polyoxyethylene glyceryl trimyristate, polyoxyethylene glyceryl tripalmitate, polyoxyethylene tristearate Examples thereof include glycerin, polyoxyethylene glyceryl trioleate, and polyoxyethylene glycerin triisostearate, and polyoxyethylene glyceryl laurate, polyoxyethylene glyceryl stearate, and polyoxyethylene glyceryl isostearate are most preferable.

Specific examples of polyoxyethylene sorbitan fatty acid esters include monoesters and diesters of sorbitan polyoxyethylene adducts having a polyoxyethylene (EO) addition mole number of 4 to 200 and fatty acids having 8 to 22 carbon atoms, Examples include triesters and tetraesters. Among these, preferred are polyoxyethylene sorbitan caprylate, polyoxyethylene sorbitan caprate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan myristate, polyoxyethylene sorbitan palmitate, polyoxyethylene sorbitan stearate, olein Polyoxyethylene sorbitan acid, polyoxyethylene sorbitan isostearate, polyoxyethylene sorbitan dicaprylate, polyoxyethylene sorbitan dicaprate, polyoxyethylene sorbitan dilaurate, polyoxyethylene sorbitan dimyristate, polyoxyethylene sorbitan dipalmitate, Polyoxyethylene sorbitan distearate, polyoxyethylene sorbitan dioleate, dii Polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan tricaprylate, polyoxyethylene sorbitan tricaprate, polyoxyethylene sorbitan trilaurate, polyoxyethylene sorbitan trimyristate, polyoxyethylene sorbitan tripalmitate, polyoxyethylene tristearate Examples include sorbitan, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan triisostearate, polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan isostearate, polyoxyethylene sorbitan trilaurate, Polyoxyethylene sorbitan tristearate, polyoxystearic acid polyoxy Ethylene sorbitan is most preferable.

Specific examples of the polyoxyethylene fatty acid ester include monoesters and diesters of polyoxyethylene (EO) having an addition mole number of 4 to 200 and a fatty acid having 8 to 22 carbon atoms. Among these, preferred are polyoxyethylene caprylate, polyoxyethylene caprate, polyoxyethylene laurate, polyoxyethylene myristate, polyoxyethylene palmitate, polyoxyethylene stearate, polyoxyethylene oleate, isostearine. Polyoxyethylene, polyoxyethylene behenate, polyoxyethylene dicaprylate, polyoxyethylene dicaprate, polyoxyethylene dilaurate, polyoxyethylene dimyristate, polyoxyethylene dipalmitate, polyoxyethylene distearate, diolein Acid polyoxyethylene, polyisoethylene diisostearate, polyoxyethylene dibehenate, etc., polyoxyethylene laurate, polystearate Kishiechiren, oleate polyoxyethylene, and most preferably isostearic acid polyoxyethylene.

Specific examples of the polyoxyethylene alkyl ether include polyoxyethylene having 4 to 200 added moles of polyoxyethylene (EO), an alkyl group having 8 to 22 carbon atoms and monoether. Among these, polyoxyethylene capryl ether, polyoxyethylene caprylyl ether, polyoxyethylene lauryl ether, polyoxyethylene myristyl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene oleyl ether, Examples thereof include polyoxyethylene isosteyl ether and polyoxyethylene behenyl ether, and polyoxyethylene lauryl ether, polyoxyethylene stearyl ether and polyoxyethylene behenyl ether are most preferable.

As the nonionic surfactant of the above component (B), the storage stability of the cosmetic composition, the transparency and dispersion stability of the aqueous dispersion prepared using the cosmetic composition, From the viewpoint of improving, it is preferable to use a mixture of two or more. The HLB of the nonionic surfactant to be used is not particularly limited, but the HLB is preferably 5 to 16, more preferably 7 to 14, as the whole component (B). Among these nonionic surfactants, from the viewpoint of improving the storage stability of fullerene, polyglycerol fatty acid ester is preferable, and polyglyceryl laurate, polyglyceryl stearate, polyglyceryl isostearate, polyglyceryl dilaurate, polyglyceryl distearate, diisostearate. Polyglyceryl acid is most preferred.

Examples of the component (C) polyhydric alcohol used in the present invention include glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl- 1,3-propanediol, trimethylolpropane, pentaerythritol, sorbitol, pentylene glycol, hexylene glycol, 1,2-hexanediol, caprylyl glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, Examples thereof include polypropylene glycol. These polyhydric alcohols may be used alone or in combination of two or more. Of these, glycerin and 1,3-butylene glycol are preferable from the viewpoint of stability, and it is more preferable to use both of them.

Component (D) oil used in the present invention includes hydrocarbon oils such as dodecane, isododecane, hexadecane, isohexadecane, liquid paraffin, heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, squalane, hydrogenated polyisobutene, etc. Palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, Argania Spinosa kernel oil, meadow foam oil, persic oil, tea tree oil, mint oil, camellia oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cacao butter, Shea butter, hydrogenated coconut oil, hydrogenated castor oil, Vegetable oils such as bar oil, hydrogenated jojoba oil; glyceryl triethylhexanoate, glyceryl tricaprylate, glyceryl tricaprate, glyceryl tri (caprylate / caprate), glyceryl trioleate, glyceryl triisostearate, trimethylolpropane triethylhexanoate , Pentaerythrityl tetraethylhexanoate, 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl-1,5-pentanediol dineopentanoate, cetyl ethylhexanoate, hexyldecyl ethylhexanoate, isononyl isononanoate , Isodecyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, Isopropyl myristate, hexyldecyl myristate, octyldodecyl myristate, isopropyl palmitate, ethylhexyl palmitate, cetyl palmitate, octyldodecyl palmitate, ethyl oleate, oleyl oleate, octyldodecyl oleate, isopropyl isostearate Octyldodecyl, octyldodecyl erucate, lanolin fatty acid isopropyl, lanolin fatty acid octyldodecyl, dicaprylyl carbonate, diethylhexyl succinate, diisopropyl adipate, diisobutyl adipate, diethyl sebacate, diisopropyl sebacate, diethylhexyl sebacate, triethyl citrate, Diisostearyl malate, diisostearyl malate diisostearyl, dimer Ester oils such as di (isostearyl / phytosteryl) nolate, N-lauroyl-L-glutamate di (phytosteryl / octyldodecyl); (eicosandioic acid / tetradecandioic acid) polyglyceryl-10, bisethoxydiglycol succinate, cyclohexane Amphiphilic ester oils such as bisethoxydiglycol dicarboxylic acid; lactone derivatives such as γ-tetradecalactone, γ-hexadecalactone, γ-octadecalactone, γ-icosalactone, γ-docosalactone; dimethicone, cyclomethicone, Examples thereof include silicone oil such as phenyl dimethicone. These oil agents may be used alone, or two or more kinds may be mixed and used, and the same oil agent as used in component (A) may be included. In addition to these, oily components generally used in cosmetics can be added within a range not impairing the effects of the present invention. Among these, from the viewpoint of the stability of the cosmetic composition, it is preferable to contain a hydrocarbon oil such as liquid paraffin and squalane as an essential component, and the component (D) contains 50% by weight or more of hydrocarbon oil. Preferably it is 70% by weight or more.

The water of the component (E) used in the present invention is not particularly limited as long as it is usually usable for cosmetics, and includes purified water, ion exchange water, distilled water, natural water, deep ocean water, hydrogen water, and the like. Can be used. Further, the pH may be adjusted with an acid, an alkali, a buffering agent, a chelating agent, or the like, or a preservative may be added.

The cosmetic composition of the present invention contains the above-mentioned components (A) to (E), and is prepared using the storage stability of the cosmetic composition and the cosmetic composition. From the viewpoint of improving the transparency and dispersion stability of the aqueous dispersion, it is more preferable to have a bicontinuous structure. In the present invention, the bicontinuous structure means a state in which both the water phase and the oil phase form a continuous phase, and the oil phase or the water phase is in the medium having the water phase or the oil phase as a continuous phase. Means different from the general dispersed emulsion form. When it has a bicontinuous structure, both the water phase and the oil phase form a continuous phase. Therefore, when adding a solution in which a water-soluble pigment is dissolved in water, and when an oil-soluble pigment is dissolved in oil In any case where the liquid is added, the composition is uniformly colored in the hue of the respective pigment. Such a method can be used to confirm the bicontinuous structure. It can also be confirmed by a method combining observation with an electron microscope by a freeze-fracture replica method, observation of appearance, observation with an optical polarization microscope, measurement of electrical conductivity, and the like.

The content of each component of the cosmetic composition of the present invention is such that the content of the component (A) is 1 to 20% by weight and the content of the component (B) is 15 from the viewpoint of forming a bicontinuous structure. 45% by weight, the content of component (C) is 10 to 35% by weight, the content of component (D) is 5 to 35% by weight, and the content of component (E) is 10 to 40% by weight. More preferably, the content of the component (A) is 5 to 15% by weight, the content of the component (B) is 20 to 40%, the content of the component (C) is 15 to 30% by weight, and the component (D ) Is 10 to 25% by weight, and the component (E) is 15 to 35% by weight. There is no restriction | limiting in particular in the manufacturing method of the composition for cosmetics of this invention, It can prepare by stirring each component uniformly.

The cosmetic composition of the present invention thus obtained can be easily added to an aqueous medium and stirred to prepare an aqueous dispersion containing fullerene. At this time, a special apparatus such as a vortex mixer or a homogenizer is not necessary, and the production can be sufficiently performed with a stirring force such as a propeller or a stirrer. Moreover, it is not necessary to heat at the time of dispersion, and it can be produced at room temperature. Further, the fullerene-containing aqueous dispersion obtained in this way has a transparent appearance, and its dispersion stability is very good. In the present invention, “transparency” means that the appearance of the liquid is transparent when the sample is placed in a glass bottle having a diameter of 3.5 cm and observed from the side. When measuring turbidity with a spectrophotometer, the transmittance is 60% or more when a sample is put in a cell having a thickness of 1 cm and measured at a wavelength of 600 nm.

The amount of the cosmetic composition of the present invention added to the cosmetic is not particularly limited, but is preferably 0.01 to 30% by mass, more preferably 0, from the viewpoint of the appearance and stability of the resulting cosmetic. .05 to 10% by mass.

In the cosmetic containing the cosmetic composition of the present invention, water and additives added to normal cosmetics as necessary, such as oil bases, surfactants, alcohols, moisturizers, polymers, Thickening / gelling agent, antioxidant, antiseptic, bactericidal agent, chelating agent, pH adjuster / acid / alkali, UV absorber, whitening agent, solvent, exfoliating / dissolving agent, antipruritic agent, anti-inflammatory agent, antibacterial agent Sweat, refreshing agent, antihistamine, astringent, stimulant, hair-growth agent / blood circulation promoter, reducing agent / oxidant, polymer powder, hydroxy acid, vitamins and derivatives thereof, saccharides and derivatives thereof, organic Acids, enzymes, nucleic acids, hormones, inorganic powders, fragrances, pigments and the like may be contained to the extent that the effects of the present invention are not impaired.

Examples of oily bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, ceralkyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, Higher alcohols such as 2-octyldodecanol and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, Palmitooleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexene Higher fatty acids such as decanoic acid, antiisohenicosanoic acid, long-chain branched fatty acid, dimer acid, hydrogenated dimer acid, and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium, sodium salts, etc. And nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, solid Hydrocarbons such as paraffin; candelilla wax, carnauba wax, rice wax, wax wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, fisher -Tropsch wax, polyethylene wax, waxes such as ethylene propylene copolymer; palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, Macadamia nut oil, hazelnut oil, cucumber oil, rosehip oil, meadow foam oil, persic oil, tea tree oil, mint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, Vegetable oils such as rice bran oil, cacao butter, shea butter, hydrogenated palm oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; animals such as beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle oil Oils and fats; animal waxes such as whale wax, lanolin, orange luffy oil; liquid lanolin, reduced lano Lanolin, lanolin acetate, lanolin acetate, lanolin acetate, liquid lanolin acetate, hydroxy lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, acetic acid lanolin alcohol, acetic acid (cetyl lanolyl) ester; lecithin, phosphatidylcholine , Phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingophospholipids such as sphingomyelin, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof, phospholipids such as lysolecithin; hydrogenated soybean phospholipid, partially hydrogenated soybean Phospholipids such as phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids; cholesterol, dihydrocholesterol, lanostero , Sterols such as dihydrolanosterol, phytosterol, and cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonate, cholesteryl stearate, cholesteryl isostearate, cholesteryl oleate, N-lauroyl-L-glutamate di (cholesteryl / Behenyl / octyldodecyl), N-lauroyl-L-glutamate di (cholesteryl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / octyl) Dodecyl), acyl sarcosine alkyl esters such as N-lauroyl sarcosine isopropyl, cholesteryl 12-hydroxystearate, macadamia nut oil fatty acid cholesterol Sterol esters such as steryl, macadamia nut oil fatty acid phytosteryl, sunflower seed oil fatty acid phytosteryl, phytosteryl isostearate, soft lanolin fatty acid cholesteryl, hard lanolin fatty acid cholesteryl, long chain branched fatty acid cholesteryl, long chain α-hydroxy fatty acid cholesteryl; phospholipids and cholesterol Complexes, lipid complexes such as phospholipid / phytosterol complexes; octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl parimilate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isononanoic acid Isotridecyl, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, isodecyl neopentanoate, Isotridecyl pentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, lanolin fatty acid octyldodecyl, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate, isostearic acid cure Castor oil, ethyl oleate, avocado oil fatty acid ethyl, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, lanolin fatty acid isopropyl, methyl heptyl laurate, methyl heptyl palmitate, methyl heptyl palmitate, methyl isostearate Heptyl, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, Monoalcohol carboxylic acid esters such as diisopropyl dipinate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl succinate, triethyl citrate; cetyl lactate, diisostearyl malate, monoisostearic acid hydrogenated castor oil, γ-ercalactone Oxyesters such as: glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, glyceryl tri (caprylic acid / capric acid), tri (caprylic acid / capric acid / myristic acid / stearic acid) glyceryl , Hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), glyceryl behenate, trimethylolpropane trioctanoate, triisostester Trimethylolpropane phosphate, neopentyl glycol dioctanoate, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenated rosin Pentaerythrityl, triethylhexanoic acid ditrimethylolpropane, (isostearic acid / sebacic acid) ditrimethylolpropane, triethylhexanoic acid pentaerythrityl, (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl, diisostearate diglyceryl, tetraisostearic acid Polyglyceryl, polyglyceryl-10 nonaisostearate, deca (erucic acid / isostearic acid / ricinoleic acid) polyglyceryl-8, (Hexyldecanoic acid / sebacic acid) diglyceryl oligoester, glycol distearate (ethylene glycol distearate), 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl-1,5-pentanediol dineopentanoate, etc. Polyhydric alcohol fatty acid esters; alkyl ethers such as dicaprylyl ether; diisopropyl dilinoleate diisopropyl, dimer dilinoleate diisostearyl, dimer dilinoleate di (isostearyl / phytosteryl), dimer dilinoleate (phytosteryl / Behenyl), dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl), dimer dilinoleate dimer dilinoleyl, diisostearate dimer dilinoleyl, da Dimer acid or dimer diol derivatives such as merlinoleyl hydrogenated rosin condensate, dimer linoleic acid hydrogenated castor oil, hydroxyalkyl dimer linoleyl ether; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (Cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide (partamide) DEA), fatty acid alkanolamides such as coconut oil fatty acid methylethanolamide (cocamidomethyl MEA); dimethicone (dimethylpolysiloxane), high weight Dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopentasiloxane), phenyltrimethicone, diphenyldimethicone, phenyldimethicone, (aminoethylaminopropylmethicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, Silicone resin, silicone rubber, amino-modified silicone such as aminopropyl dimethicone and amodimethicone, polyether-modified silicone such as cation-modified silicone and dimethicone copolyol, polyglycerin-modified silicone, sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone , Sulfuric acid modified silicone, alkyl modified silicone, fatty acid modified silicone, alkyl ether modified silicone, Mino acid modified silicone, peptide modified silicone, fluorine modified silicone, cation modified and polyether modified silicone, amino modified and polyether modified silicone, alkyl modified and polyether modified silicone, amide alkyl modified silicone, amino glycol modified silicone, aminophenyl modified Preferable examples include silicones such as silicone and polysiloxane / oxyalkylene copolymer; and fluorine-based oils such as perfluorodecane, perfluorooctane and perfluoropolyether.

Examples of humectants and feel improvers include glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyols such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol / propylene glycol copolymer and polymers thereof; diethylene glycol monoethyl ether (Ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether, etc. Tells; (eicosanedioic acid / tetradecanedioic acid) water-soluble esters such as polyglyceryl-10, tetradecanedioic acid polyglyceryl-10, cyclohexanedicarboxylic acid bisethoxydiglycol; sugars such as sorbitol, xylitol, erythritol, mannitol, maltitol Alcohols; glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ- Cyclodextrins and modified cyclodextrins such as maltosylation and hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabi Sugars and derivatives thereof such as nogalactan, dextrin, dextran, glycogen, ethyl glucoside, glucosyl ethyl methacrylate polymer or copolymer; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucoitin sulfate, caroline sulfate, kerato sulfate, dermatan Sulfuric acid; white jellyfish extract, white jellyfish polysaccharides; fructans such as inulin and levan; fucoidan; tuberose polysaccharides, naturally occurring polysaccharides; organic acids such as citric acid, tartaric acid and lactic acid and salts thereof; urea; 2-pyrrolidone-5 -Carboxylic acid and its sodium salts; betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine , Glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine and other amino acids and salts thereof; collagen, fish-derived collagen, atelocollagen, gelatin, elastin, collagen degrading peptide , Hydrolyzed collagen, hydrolyzed hydroxypropylammonium chloride, elastin degrading peptide, keratin degrading peptide, hydrolyzed keratin, conchiolin degrading peptide, hydrolyzed conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soy protein Degraded peptides, wheat proteolytic peptides, hydrolyzed wheat proteins, casein degrading peptides, acylated peptides and other protein peptides and Derivatives; acylated peptides such as palmitoyl oligopeptide, palmitoyl pentapeptide, palmitoyl tetrapeptide; silylated peptides; lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesameignan glycoside , Glutathione, albumin, whey; choline chloride, phosphorylcholine; placenta extract, aerostin, collagen, aloe extract, hamamelis water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, Izayoi rose extract, yarrow extract , Eucalyptus extract, animal and plant extract ingredients such as Merrilot extract, natural ceramide (type 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide and sugar ceramide-containing extract Ceramides can be mentioned as preferred.

Preferred examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, and a polymer surfactant. There is no restriction | limiting in particular in HLB of surfactant, It can use from about 1 low thing to about 20 high thing, It is also preferable to combine a low thing and a high thing of HLB. Examples of preferable surfactants include fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfates such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and laureth sulfate triethanolamine; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amine and sodium methylalanine lauroylglutamate; Cocoyl Glue Acyl amino acid salts such as sodium phosphate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoylalanine triethanolamine, lysine Na dilauroyl glutamate; sodium laureth acetate, etc. Polyoxyethylene alkyl ether acetates; succinic acid ester salts such as sodium lauroyl monoethanolamide succinate; fatty acid alkanolamide ether carboxylates; acyl lactates; polyoxyethylene fatty amine sulfates; fatty acid alkanolamide sulfates; Fatty acid glyceride sulfate such as coconut oil fatty acid sodium glycerin sulfate; Oxyethylene sulfate; Olefin sulfonate such as sodium α-olefin sulfonate; Alkyl sulfosuccinate such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate; Disodium laureth sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sulfosuccinate Alkyl ether sulfosuccinates such as sodium acid, sodium lauryl polypropylene glycol sulfosuccinate; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate and triethanolamine tetradecylbenzenesulfonate; alkylnaphthalenesulfonate; alkanesulfonate; α-sulfo fatty acid methyl ester salt; acyl isethionate; alkyl glycidyl ether sulfonate Alkyl sulfoacetates; alkyl ether phosphates such as sodium laureth phosphate, sodium dilaures phosphate, sodium trilaureth phosphate, sodium monooles phosphate; alkyl phosphate esters such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphorus Acid salts; fatty acid amide ether phosphates; phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof; silicone-based shades such as carboxylic acid-modified silicone, phosphate-modified silicone, and sulfate-modified silicone Nonionic surfactants such as ionic surfactants, laureth (polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steale Various polyoxyethylene addition numbers such as bis (polyoxyethylene stearyl ether), behenes (polyoxyethylene behenyl ether), isosteares (polyoxyethylene isostearyl ether), octyldecesses (polyoxyethylene octyldodecyl ether) Polyoxyethylene alkyl ethers; polyoxyethylene alkyl phenyl ethers; polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, Castor oil and hardened castor oil derivatives such as polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearic acid diester, polyoxyethylene hardened castor oil maleic acid; Polyoxyethylene cholesterol; polyoxyethylene cholestanol; polyoxyethylene lanolin; polyoxyethylene reduced lanolin; polyoxyethylene / polyoxypropylene cetyl ether, polyoxyethylene / polyoxypropylene 2-decyltetradecyl ether; Polyoxyethylene / polyoxypropylene monobutyl ether, polyoxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene alkyl ethers such as polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol ; (Poly) glycerin polyoxypropylene glycol such as PPG-9 diglyceryl; glyceryl stearate Glyceryl isostearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl oleate, glyceryl palm oil fatty acid, mono-cotton oil fatty acid glycerin, glyceryl monoerucate, glyceryl sesquioleate, glycerin α, α'-pyroglutamate oleate, monostearin Glycerin fatty acid partial esters such as glyceryl malic acid; polyglyceryl stearate-2, 3, 4, 5, 6, 8, 8, disglyceryl-6, 10, polyglyceryl tristearate 2, polyglyceryl-10 decastearate, polyglyceryl-2 isostearate, 3, 4, 5, 6, 6, 8, 10 diglyceryl-2 diisostearate (diglyceryl diisostearate), 3, 1 , Polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3, 4, 5, 6, 8, 10, dioleate polyglyceryl- 6, polyglyceryl fatty acid ester such as polyglyceryl-2 trioleate, polyglyceryl-10 dekaleate; ethylene glycol mono fatty acid ester such as ethylene glycol monostearate; propylene glycol mono fatty acid ester such as propylene glycol monostearate; pentaerythritol moiety Fatty acid ester; sorbitol partial fatty acid ester; maltitol partial fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate Sorbitan fatty acid esters such as sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; Sugar derivatives partial esters such as sucrose fatty acid ester, methyl glucoside fatty acid ester and undecylenic acid trehalose; alkyl glucoside such as caprylyl glucoside; alkyl polyglycoside; glycolipid such as mannosyl erythritol lipid; lanolin alcohol; reduced lanolin; Stearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene dioleate, etc. Polyoxyethylene fatty acid mono- and diesters; polyoxyethylene propylene glycol fatty acid esters; polyoxyethylene monooleates such as polyoxyethylene glycerin monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate Polyoxyethylene glycerin fatty acid esters such as polyoxyethylene sorbitan monooleate; polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monooleate, and other polyoxyethylene sorbitan fatty acid esters; poly Oxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene Polyoxyethylene sorbitol fatty acid esters such as bitol pentaoleate and polyoxyethylene sorbitol monostearate; Polyoxyethylene methyl glucoside fatty acid ester; Polyoxyethylene alkyl ether fatty acid ester; Polyoxyethylene animal and vegetable oils such as polyoxyethylene sorbitol beeswax Alkyl glyceryl ethers such as isostearyl glyceryl ether, chimyl alcohol, ceralkyl alcohol, and batyl alcohol; polyhydric alcohol alkyl ether; polyoxyethylene alkylamine; tetrapolyoxyethylene / tetrapolyoxypropylene-ethylenediamine condensates; Natural surfactants such as saponins and sophorolipids; polyoxyethylene fatty acid amides; coconut oil fatty acid monoethano Luamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide Fatty acid alkanolamides such as (partamide MEA), palmitic acid diethanolamide (partamide DEA), and palm oil fatty acid methylethanolamide (cocamidomethyl MEA); alkyl such as lauramine oxide, cocamamine oxide, stearamine oxide, and behenamine oxide Polydimethyl ether oxide; alkyl ethoxy dimethyl amine oxide; polyoxyethylene alkyl mercaptan; polyether such as dimethicone copolyol Silicone-based nonionic surfactants such as silicone-modified silicones, polysiloxane / oxyalkylene copolymers, polyglycerin-modified silicones, sugar-modified silicones, etc .; for cationic surfactants, behentrimonium chloride, steartrimonium chloride Alkyltrimethylammonium chloride such as cetrimonium chloride and lauryltrimonium chloride; alkyltrimethylammonium bromide such as stearyltrimonium bromide; dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; stearamidepropyldimethylamine; Fatty acid amidoamines such as stearamide ethyl diethylamine and salts thereof; alkyl ether amines such as stearoxypropyldimethylamine; and Salts or quaternary salts of fatty acids; fatty acid amide type quaternary ammonium salts such as ethyl sulfate long-chain branched fatty acid (12-31) aminopropylethyldimethylammonium and ethyl lanolin sulfate fatty acid aminopropylethyldimethylammonium; polyoxyethylene alkylamine and its Alkylamine salt; fatty acid amidoguanidinium salt; alkyl etheraminemonium salt; alkyltrialkylene glycol ammonium salt; benzalkonium salt; benzethonium salt; pyridinium salt such as cetylpyridinium chloride; imidazolinium salt Alkyl isoquinolinium salts; dialkyl morpholinium salts; polyamine fatty acid derivatives; amino-modified silicones such as aminopropyl dimethicone and amodimethicone; cation-modified silicones; And silicone-based cationic surfactants such as polyether-modified silicone, amino-modified and polyether-modified silicone; amphoteric surfactants such as lauryl betaine (lauryldimethylaminoacetic acid betaine) and the like N-alkyl-N, N- Dimethylamino acid betaine; fatty acid amide alkyl-N, N-dimethylamino acid betaine such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline type betaine such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaine such as alkyldimethyltaurine; alkyl Sulfate-type betaines such as dimethylaminoethanol sulfate; Phosphorus-type bases such as alkyldimethylaminoethanol phosphate






Tyne; phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, sphingomyelin and other sphingophospholipids, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, hydroxylated lecithin Phospholipids such as: silicone-based amphoteric surfactants; polymer surfactants include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, acrylic acid / methacrylic acid alkyl copolymers; various silicone-based surfactants It is mentioned as preferable.

Polymers, thickeners and gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, arabic gum, tara gum, tamarind, far selelain, karaya gum, troarooi, cara gum, tragacanth gum, pectin, pectic acid and sodium Salt such as salt, salt such as alginic acid and sodium salt, mannan; starch such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salt, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, gypsophila extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypro Cellulose, carboxymethylcellulose and its sodium salts, methylhydroxypropylcellulose, sodium cellulose sulfate, cellulose dialkyldimethylammonium sulfate, crystalline cellulose, cellulose powder such as cellulose powder; soluble starch, carboxymethyl starch, methylhydroxypropyl starch , Starch-based polymers such as methyl starch, starch derivatives such as hydroxypropyltrimonium chloride, octenyl succinic acid corn starch aluminum; alginic acid derivatives such as sodium alginate and propylene glycol alginate; polyvinylpyridone (PVP), polyvinyl alcohol (PVA) , Vinyl pydridone-vinyl alcohol copolymer, polyvinyl methyl ester Ter; polyethylene glycol, polypropylene glycol, polyoxyethylene / polyoxypropylene copolymers; amphoteric methacrylic acid such as (methacryloyloxyethylcarboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine methacrylate oxide) copolymer Ester copolymer; (Dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP; Polyvinyl acetate partial saponification product, maleic acid copolymer; Vinylpyrrolidone / dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; poly Acrylamide; Polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its sodium salt, acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate Polymer: Cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, acrylic acid such as polyquaternium-39・ Diallyldimethylammonium chloride / acrylamide copolymer, acrylic acid / cationized methacrylic acid ester copolymer, acrylic acid / cationized methacrylic acid amide copolymer, polyquatani -47 etc. acrylic acid / methyl acrylate / methacrylamidopropyltrimethylammonium chloride copolymer, methacrylic acid choline ester polymer; cationized polysaccharide such as cationized oligosaccharide, cationized dextran, guar hydroxypropyltrimonium chloride Polyethyleneimine; cationic polymer; 2-methacryloyloxyethyl phosphorylcholine polymer such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; acrylic resin emulsion, polyethyl acrylate emulsion, polyacrylalkyl ester emulsion , Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex, synthetic latex; nitrocellulose; polyurethanes and various copolymers; Various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluoropolymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride , Fumed silica (ultrafine silica), magnesium magnesium silicate, sodium magnesium silicate, metal soap, dialkyl phosphate metal salt, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, fructooligosaccharide fatty acid ester Is preferable.

Solvents and propellants include ethanol, 2-propanol (isopropyl alcohol), butanol, isobutyl alcohol and other lower alcohols; propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, isopentyl diol and other glycols Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether Glycol ether esters such as diacetate, diethylene glycol monoethyl ether acetate, propylene glycol monoethyl ether acetate; glycol esters such as diethoxyethyl succinate, ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, carbonic acid Preferred examples include dialkyl, acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbon, next-generation fluorocarbons; LPG, dimethyl ether, carbon dioxide, and the like.

Antioxidants include tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or derivatives thereof; erythorbic acid and derivatives thereof; Preferred are sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfites; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, cysteine hydrochloride As mentioned. Preferred examples of the reducing agent include thioglycolic acid, cysteine, cysteamine and the like. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate.

Antibacterial agents or antiseptics include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, 1,2-octane 1,2-alkanediols such as diols; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether (ethylhexyl glycerin); salicylic acid; sodium benzoate; isothiazolinone derivatives such as methyl chloroisothiazolinone and methylisothiazolinone; Dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, chloride Sarkonium, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, sodium phenylphenol; phenylethyl alcohol , Photosensitizers, antibacterial zeolite, and silver ion are preferable, but when used as an antibacterial agent or antiseptic agent for antiseptic purposes, phenoxyethanol; 1 from the viewpoint of safety of cosmetics or skin external preparations; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol; alkylglycols such as 2-ethylhexylglyceryl ether It is more preferable to use a Rirueteru acids.

Examples of chelating agents include edetate (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; Phosphonic acid and its sodium salt; sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine Gluconic acid, ascorbic acid, succinic acid, and tartaric acid are preferable. pH adjusters / acids / alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol Amine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxylated Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferable.

Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorine apatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (for example, zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, bengara, yellow iron oxide, black iron oxide, ultramarine, bitumen, carbon black, titanium oxide, fine particles and super Titanium oxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silica), mica titanium, fish scale foil, boron nitride, photochromic pigment, synthetic fluorophlogopite, fine particle composite powder Body, gold, aluminum, etc., various sizes and shapes of inorganic powders, and these are treated with various surface treatment agents such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents Inorganic powders such as hydrophobized or hydrophilized powders; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, Benzoguanamine resin powder, polyethylene terephthalate, polymethy Organic powders and surface-treated powders of various sizes and shapes, such as polyurethane powder, polyethylene terephthalate / aluminum / epoxy powder, urethane powder, silicone powder, Teflon (registered trademark) powder, organic-inorganic composite powder The body is preferred. Inorganic salts include sodium chloride-containing salts such as salt, common salt, rock salt, sea salt, natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum sulfate / potassium sulfate (alum), aluminum sulfate / ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na and 3Na phosphates, phosphoric acid Potassium, calcium phosphates and magnesium phosphates are preferred.

Examples of ultraviolet absorbers include paraaminobenzoic acid, paraaminobenzoic acid monoglycerin ester, N, N-dipropoxyparaaminobenzoic acid ethyl ester, N, N-diethoxyparaaminobenzoic acid ethyl ester, and N, N-dimethylparaaminobenzoic acid ethyl ester. Benzoic acid ultraviolet absorbers such as esters, N, N-dimethylparaaminobenzoic acid butyl ester, N, N-dimethylparaaminobenzoic acid ethyl ester; Anthranilic acid ultraviolet absorbers such as homomenthyl-N-acetylanthranilate; Salicylic acid And salicylic acid systems such as sodium salt, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate External line absorbent: octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p- Methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (sinoxate), Cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxy Cinnamic acid UV absorbers such as nanmate, ferulic acid and derivatives thereof; 2,4-dihydroxybenzophenone, 2,2′-dihydroxy-4-methoxybenzophenone, 2,2′-dihydroxy-4,4′-dimethoxybenzophenone, 2,2 ′, 4,4′-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4′-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone -5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone, etc. Benzophenone series External line absorber; 3- (4′-methylbenzylidene) -d, l-camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2′-hydroxy-5- 2- (2′-hydroxy-5′-t-octylphenyl) benzotriazole; 2- (2′-hydroxy-5′-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 5- (3 , 3-dimethyl-2-norbornylidene) -3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyl triazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2- (2′-hydroxy-5′-methylphenyl) benzotriazole, 1- 3,4-dimethoxyphenyl) -4,4-dimethyl-1,3-pentanedione, dimethoxybenzylidenedioxoimidazolidinepropionate 2-ethylhexyl, etc. hydantoin derivatives, phenylbenzimidazolazosulfonic acid, terephthalylidene dicamphor Preferred are sulfonic acid, drometrizole trisiloxane, methyl anthranilate, rutin and derivatives thereof, oryzanol and derivatives thereof.

Vitamins and their derivatives include vitamin A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinic acid such as nicotinic acid amide / benzyl nicotinate, vitamin B group such as choline; vitamin C such as ascorbic acid and its sodium salt; vitamin D; α, Vitamin E such as β, γ, and δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphates such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt, Ascorbic acid fatty acid esters such as ascorbyl tetraisopalmitate, ascorbyl stearate, ascorbyl palmitate and ascorbyl dipalmitate, ascorbic acid alkyl ethers such as ascorbic acid ethyl ether, ascorbic acid glucosides such as ascorbic acid-2-glucoside and Ascorbic acid derivatives such as fatty acid esters and tocopheryl phosphate ascorbyl; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol acetate, tocopherol linoleate, tocopherol phosphate, tocopherol phosphate etc., tocotrienol, and other various vitamin derivatives Is preferable.

Anti-inflammatory and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, chlorpheniramine maleate; peach leaf extract A plant extract such as a koji leaf extract is preferable. Plant growth and tinctures such as assembly extract, red pepper tincture, ginger tincture, ginger extract, cantalis tincture; capsaicin, nonyl acid valenylamide, gingeron, ictamol, tannic acid Borneol, cyclandrate, cinnarizine, trazoline, acetylcholine, verapamil, cephalanthin, γ-oryzanol, cephalanthin, vitamin E and derivatives such as tocopherol / nicotinic acid tocopherol, γ-oryzanol, nicotinic acid and nicotinamide / benzyl nicotinate Derivatives such as ester, inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Preferable examples include flavonol derivatives, stigmasterol or stigmasteranol, its glycosides, and minoxidil. Preferred hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone and the like. Other remedies such as anti-wrinkle agents, anti-aging agents, squeeze agents, cooling sensations, warming sensation agents, wound healing promoters, irritation relievers, analgesics, cell activators include retinols, retinoic acids, retinoin Acid tocopheryl; derivatives such as lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and glycosides / esterified products thereof, α- or such as hydroxycapric acid, long chain α-hydroxy fatty acid, long chain α-hydroxy fatty acid cholesteryl β-hydroxy acids and derivatives thereof; γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine and the like; coenzyme Q10, carotene, lycopene , Astaxanthin, lutein, α-lipoic acid, platinum nanocolloid, fullerenes, etc. Antioxidant / active oxygen scavengers; catechins; flavones such as quercetin; isoflavones; gallic acid and ester sugar derivatives; polyphenols such as tannin, sesamin, protoanthocyanidin, chlorogenic acid, apple polyphenol; rutin and glycosides, etc. Derivatives of hesperidin and glycosides; lignan glycosides; licorice extract-related substances such as grabrizine, glabrene, liquiritin, and isoliquiritin; lactoferrin; shogaol, gingerol; fragrance substances such as menthol, camphor, cedrol, and derivatives thereof Preferred examples include capsaicin, vanillin and the like and derivatives; insect repellents such as diethyltoluamide; and complexes of physiologically active substances and cyclodextrins.

As plant / animal / microbe extracts, Iris extract, Ashitaba extract, Asunaro extract, Asparagus extract, Avocado extract, Achacha extract, Almond extract, Altea extract, Arnica extract, Aloe extract, Apricot extract, Ginkgo biloba extract, Ginkgo biloba extract , Incheon extract, Fennel extract, Turmeric extract, Oolong tea extract, Peony extract, Ages extract, Echinacea leaf extract, Enmeo extract, Ogon extract, Oat extract, Auren extract, Barley extract, Panax ginseng extract, Hypericum extract, Odori extract , Dutch mustard extract, orange extract, dried seawater, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, water content Silk, Cascon extract, Chamomile extract, Oil-soluble chamomile extract, Carrot extract, Kawara mugi extract, Oat extract, Calcade extract, Licorice extract, Oil-soluble Licorice extract, Kiwi extract, Kiou extract, Cyprid extract, Quina extract, Cucumber extract, Kiri leaf extract, Guanosine, guava extract, cucumber extract, gardenia extract, kumazasa extract, clara extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar, chlorella extract, mulberry extract, gentian extract, Gentian pepper extract, tea Extract, yeast extract, kokuboku extract, coffee extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract Collagen, Cowberry extract, Saishin extract, Psycho extract, Saitai extract, Saffron extract, Salvia extract, Salmon extract, Sasa extract, Hawthorn extract, Sansha extract, Salamander extract, Shiitake extract, Giant extract, Shikon extract, Perilla extract, Linden extract, Shimosukeso Extract, jatoba extract, peonies extract, ginger cucumber extract, ginger root extract, white birch extract, white jellyfish extract, horsetail extract, stevia extract, stevia fermented product, west river willow extract, horse chestnut extract, hawthorn extract, elderberry extract, yarrow extract , Mint extract, sage extract, mallow extract, nematode extract, assembly extract, Sakuhakuhi extract, Diou extract, da Izu extract, Tissou extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, chigaya extract, chimpi extract, tea tree oil, tea tea extract, red pepper extract, toukiki extract, toukisenka extract, tonin extract, spruce extract, dokudami extract, tomato Extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, bacmond extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, hyacinth extract, bisabolol, cypress extract, bifidobacteria extract, Biwa extract, dandelion extract, burdock extract, bukkuri extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract Safflower extract, peppermint extract, body extract, button extract, hop extract, squid extract, pine extract, maroonnier extract, citrus extract, sorghum extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, yukinoshita extract, yuzu extract, lily extract , Yokuinin extract, Artemisia extract, Lavender extract, Green tea extract, Egg shell membrane extract, Apple extract, Rooibos tea extract, Ganoderma extract, Lettuce extract, Lemon extract, Forsythia extract, Forsythia extract, Rose extract, Rosemary extract, Roman chamomile extract, Extracts such as royal jelly extract and bitumen extract are preferred.

Examples of antipruritic agents include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitor and the like. Examples of the exfoliating / dissolving agent include salicylic acid, sulfur, resorcin, selenium sulfide, pyridoxine and the like. Examples of the antiperspirant include chlorohydroxyaluminum, aluminum chloride, zinc oxide, and zinc paraphenol sulfonate. Examples of the refreshing agent include menthol and methyl salicylate. Examples of the astringent include citric acid, tartaric acid, lactic acid, aluminum sulfate / potassium sulfate, and tannic acid. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease, and the like. Preferred nucleic acids include ribonucleic acid and salts thereof, deoxyribonucleic acid and salts thereof, and adenosine triphosphate disodium.

As perfumes, acetyl cedrene, amylcinnamaldehyde, allyl amyl glycolate, β-ionone, iso-Esuper, isobutyl quinoline, Iris oil, Iron, indole, ylang ylang oil, undecanal, undecenal, γ-undecalactone, Estragole, Eugenol, Oak Moss, Opoponax Resinoid, Orange Oil, Eugenol, Auranthiol, Galac Solid, Carvacrol, L-Carbon, Camphor, Cannon, Carrot Seed Oil, Clove Oil, Methyl Cinrate, Geraniol, Geraniol Nitrile , Isobornyl acetate, geranyl acetate, dimethylbenzyl carvinyl acetate, styrylyl acetate, cedolyl acetate, terpinel acetate, pt-butylcyclohexyl acetate, vetiberyl acetate, benzyl acetate, Linalyl acid, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrsenol, jasmine absolute, jasmine lactone, cis-jasmon, citral, citronenol, citronellal , Cinnamon bark oil, 1,8-cineole, cinnamaldehyde, stylax resinoid, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascon, damassenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene , Tripral, nerol, nonanal, 2,6-nonadienol, nonalactone, patchouli alcohol, vanilla absolute , Vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitglen oil, hexylcinnamaldehyde, cis-3-hexenol, perubalsum, vetiver oil, vetiverol, peppermint oil , Pepper oil, heliotropin, bergamot oil, benzylbenzoate, borneol, milresinoid, musk ketone, methylnonylacetaldehyde, γ-methylyonone, menthol, L-menthol, L-menton, eucalyptus oil, β-yonone, lime oil, lavender oil Synthetic and natural flavors such as D-limonene, linalool, linal, rillial, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, and various blended fragrances It can be mentioned as preferred.

As pigments / colorants / dyes / pigments, brown 201, black 401, purple 201, purple 401, blue 1, blue 2, blue 201, blue 202, blue 203, blue 204 , Blue 205, Blue 403, Blue 404, Green 201, Green 202, Green 204, Green 205, Green 3, Green 401, Green 402, Red 102, Red 104-1 Red 105-1, Red 106, Red 2, Red 201, Red 202, Red 203, Red 204, Red 205, Red 206, Red 207, Red 208, Red 213 Red 214, Red 215, Red 218, Red 219, Red 220, Red 221, Red 223, Red 225, Red 226, Red 227, Red 228, Red 23 No.-1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503, Red 504, Red 505, Red 506, Orange 201, Orange 203, Orange 204, Orange 205, Orange 206, Orange 207, Orange 401, Orange 402, Orange 403, Yellow 201, Yellow 202 -1, Yellow 202-2, Yellow 203, Yellow 204, Yellow 205, Yellow 4, Yellow 401, Yellow 402, Yellow 403-1, Yellow 404, Yellow 405, Yellow 406 No., Yellow 407, Yellow 5 etc .; other acid dyes such as Acid Red 14; basic dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, Arianor Straw Yellow; HC Yellow 2, HC Yellow 5, nitro dyes such as HChyRed 3, 4-hydoxypropylamino-3-nitrophenol, N, N'-bis (2-hydroxyethyl) -2-nitro-p- phenylenediamine, HC Blue 2, Basic Blue 26; disperse dyes; dioxide Inorganic white pigments such as titanium and zinc oxide; Inorganic red pigments such as iron oxide (Bengara) and iron titanate; Inorganic brown pigments such as γ-iron oxide; Inorganic yellow pigments such as yellow iron oxide and loess; Black Inorganic black pigments such as iron oxide and low-order titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; inorganic green pigments such as chromium oxide, chromium hydroxide and cobalt titanate; inorganic blue pigments such as ultramarine and bitumen Pigments: Titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil, etc .; aluminum powder, kappa Metal powder pigments such as powder and gold; surface-treated inorganic and metal powder pigments; red 201, red 202, red 204, red 205, red 220, red 226, red 228, red 405, orange No. 203, Orange No. 204, Yellow No. 205, Yellow No. 401, Blue No. 404, Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205 Organic pigments such as zirconium, barium or aluminum lake such as yellow No. 4, yellow No. 5, yellow No. 202, yellow No. 203, green No. 3 and blue No. 1; surface treatment organic pigments; anthraquinones such as astaxanthin and alizarin; Anthocyanidin, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin, crocin, chlorophyll, Natural pigments and dyes such as naphthoquinones such as cumin, cochineal, shikonin, bixin, flavones, betacyanidine, henna, hemoglobin, lycopene, riboflavin, rutin; p-phenylenediamine, toluene-2,5-diamine, o-, Oxidative dye intermediates and couplers such as m-, or p-aminophenol, m-phenylenediamine, 5-amino-2-methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine and their salts; indoline, etc. An auto-oxidizing dye of the following: dihydroxyacetone is preferred.

Examples of preferable water include normal water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionic water, and cluster water.

In addition to these, cosmetic ingredient standards, cosmetic ingredient-specific formulation standards, Japan Cosmetic Industry Association ingredient name list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Quasi-drug ingredient standards, Japanese Pharmacopoeia, Pharmaceutical Additives Ingredients listed in standards, official food additives, etc., and Japanese and foreign patent publications and patent publications (including publications and republications) in which the international patent classification IPC belongs to the classification of A61K7 and A61K8 It is possible to contain known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as the ingredients described, in known combinations, blending ratios and blending amounts.

The types of cosmetics of the present invention include hair cosmetics, basic cosmetics, makeup cosmetics, aromatic cosmetics, body cosmetics, skin external preparations such as ointments, and the like. From the viewpoint of exerting the effects of the present invention, it can be preferably used particularly for hair cosmetics and basic cosmetics. The cosmetic of the present invention can be produced according to a usual method.

The types of cosmetics of the present invention will be described in more detail. Examples of hair cosmetics include oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, hair color shampoos, shampoos with integrated rinses, rinses, treatments, Conditioners such as hair packs, hair mists, hair foams, hair mousses, hair sprays, hair waxes, hair gels, hair creams, water greases, set lotions, pomades, tics, etc .; color lotions, hair tonics, hair liquids, hair blows, branches Hair coat, hair oil, permanent wave agent, straight permanent agent, oxidative hair dye, hair bleach, hair color pretreatment, hair color after treatment, permanent pretreat Cement, permanent after-treatments, hair manicure, and as hair growth agents are preferred.

Basic cosmetics include soft lotion, astringent lotion, cleansing lotion, multi-layer lotion, etc .; emollient lotion, moisture lotion, milky lotion, nourishing lotion, nourishing milk, skin moisture, moisturizer -Emulsions such as emulsion, massage lotion, cleansing lotion, protect emulsion, sun protect, sun protector, UV care milk, sunscreen, makeup lotion, horny smoother, elbow lotion, hand lotion, body lotion; emollient cream, nutritional cream, Nourishing cream, burnishing cream, moisture cream, night cream, massage cream, cleansing cream, makeup cream, basque Cream, pre-makeup cream, sunscreen cream, suntan cream, hair removal cream, deodorant cream, shaving cream, keratin softening cream, etc .; gel such as moisture gel; essence such as moisturizing essence, whitening essence, UV protection essence Liposome cosmetics such as liposomal serum and liposome lotion; Peel-off pack, powder pack, washing pack, oil pack, cleansing mask and other packs and masks; cleansing foam, cleansing cream, cleansing milk, cleansing lotion, cleansing gel, Facial cleansers such as cleansing oil, cleansing mask, washing powder, face washing powder, etc .; cosmetic soap, transparent soap, medicated soap, liquid soap, shaving soap, synthetic cosmetic stone Soap and the like as preferred.

As makeup cosmetics, white powder, dusting powder, foundations, lipsticks, lip gloss, blusher, eyeliner, mascara, eye shadow, eyebrow, eyebrow, nail enamel, enamel remover, and nail treatment are preferable. .

Perfumes, perfumes, parfum, eau de parfum, eau de toilette, eau de cologne, perfumes, fragrance powders, perfume soaps, body lotions and bath oils are preferred as the aromatic cosmetics.

Body cosmetics include body shampoos and other body cleansers, deodorant lotions, deodorant powders, deodorant sprays, deodorant sticks and other deodorant cosmetics, depigmenting agents, depilation / hair removal agents, bathing agents, insect repellents, etc. A repeller is preferred.

Moreover, as a skin external preparation, it can be used in dosage forms such as an ointment, a patch, a lotion, a liniment, and a liquid coating agent. It can also be used as an oral cosmetic such as toothpaste and mouthwash.

As the dosage form of the cosmetic or external preparation for skin of the present invention, emulsification such as oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, O / W / O type, etc. Type cosmetics, oily cosmetics, solid cosmetics, liquid cosmetics, paste cosmetics, stick cosmetics, volatile oil cosmetics, powder cosmetics, jelly cosmetics, gel cosmetics, pastes Preferred examples include cosmetics, emulsified polymer cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

The present invention will be described in more detail with reference to the following examples, but the present invention is not limited thereto.

Preparation of Fullerene-Dissolved Oil of Component (A) 300 g of toluene was added to 0.3 g of fullerene (C ₆₀ , C ₇₀ mixture), and the mixture was stirred and dissolved at room temperature for 2 hours, followed by filtration with a 0.2 μm PTFE membrane filter. After adding 99.7 g of each oil agent having the composition shown in Table 1 to the obtained filtrate, toluene was distilled off under reduced pressure using a rotary evaporator (80 ° C., 0.1 MPa, 2 hours), and further filtered through a 1 μm PTFE membrane filter. The component (A) fullerene-dissolved oil of the present invention was obtained. All the fullerene-dissolved oils thus obtained were brown solutions. About the obtained fullerene-dissolved oil, the concentration of fullerene C ₆₀ was analyzed by HPLC under the following conditions, and the results are also shown in the lower column of Table 1.
<HPLC fullerene analysis conditions>
Detector: UV absorbance 340nm

Column: Inertsil ODS-2 4.6 × 250 mm GL Science Co., Ltd.
Column temperature: 40 ° C
Mobile phase: Weigh 420 mL of methanol and add toluene to 1000 mL.

From the results in Table 1, the content of fullerene C ₆₀ in the fullerene-dissolved oil obtained by the above-described preparation method was 0.03 to 0.15% by weight. It was found that the content of fullerene is particularly high in the oil containing γ-docosalactone.

Preparation and Evaluation of Cosmetic Composition of the Present Invention Each component was uniformly stirred and mixed with the composition shown in Table 2 to prepare a cosmetic composition of the present invention containing components (A) to (E) ( Examples 1 to 6). Similarly, cosmetic compositions having the compositions shown in Table 3 were prepared (Reference Examples 1 to 6). About the obtained cosmetic composition, the appearance, the presence / absence of formation of a bicontinuous structure, and storage stability were evaluated by the following methods, and the results are shown in Tables 2 and 3 below.
<Confirmation of bicontinuous structure>
20 g of the cosmetic composition was placed in a glass screw bottle, and 0.1 g of an aqueous solution containing 0.01% water-soluble pigment (purple 401) was added. Similarly, 0.1 g of a 0.01% concentration oil-soluble pigment (red No. 225) -containing squalane solution was added in another container. Visually observe the appearance of the composition with these dyes added and form a bicontinuous structure when both the water-soluble and oil-soluble dyes are uniformly colored and transparent. It was judged that On the other hand, when it was not uniformly colored or turbid with either or both of the pigments, it was judged that no pigment was formed.
○: All pigments are uniformly colored and have transparency ×: Not uniformly colored with either or both pigments, or liquid becomes cloudy <Storage stability of cosmetic composition>
The obtained cosmetic composition was subjected to a storage stability test at 50 ° C./month and evaluated according to the following evaluation criteria.
○ ・ ・ ・ The appearance does not change after storage. × ・ ・ ・ It is cloudy from the beginning after storage or separated into two phases.

As a result of Tables 2 and 3, the cosmetic compositions of Examples 1 to 6 and Reference Examples 1 to 6 were able to disperse fullerene easily. Among them, the cosmetic compositions of Examples 1 to 6, which had formed a bicontinuous structure, were transparent in appearance and excellent in storage stability. On the other hand, the cosmetic compositions of Reference Examples 1 to 6 that did not form a bicontinuous structure had a turbid appearance from the beginning, resulting in poor storage stability.

Preparation and Evaluation of Fullerene-Containing Aqueous Dispersion Fullerene-containing aqueous dispersions having the compositions shown in Tables 4 and 5 were prepared using the cosmetic compositions of Examples 1 to 6 and Reference Examples 1 to 6. The preparation was performed by adding 49 g of water in which methylparaben was dissolved in a 100 mL beaker, slowly adding 1 g of each cosmetic composition while stirring with a stirrer (600 rpm), and stirring at room temperature for 5 minutes. The resulting aqueous dispersion was evaluated for initial dispersibility, transparency / transmittance, and dispersion stability by the following methods, and the results are shown in Tables 4 and 5 below.
<Initial dispersibility of aqueous dispersion>
About the obtained aqueous dispersion, the dispersion state immediately after preparation was observed visually, and the initial dispersibility was evaluated according to the following evaluation criteria.
○ ・ ・ ・ Uniformly dispersed × ・ ・ ・ Not uniformly dispersed <Transparency and transmittance of aqueous dispersion>
The obtained aqueous dispersion was put in a glass bottle having a diameter of 3.5 cm, the appearance was visually observed from the side, and the transparency was evaluated according to the following evaluation criteria. Further, the transmittance of the aqueous dispersion was measured using a spectrophotometer (cell thickness: 1 cm, wavelength: 600 nm).
○ ... The back of the liquid is transparent. × ... The back of the liquid is not transparent. <Dispersion stability of aqueous dispersion>
The obtained aqueous dispersion was subjected to a storage stability test at 50 ° C./month, and the dispersion stability was evaluated according to the following evaluation criteria.
○ ・ ・ ・ Uniformly dispersed after storage × ・ ・ ・ Not uniformly dispersed after storage or precipitation occurs

From the results of Tables 4 and 5, the aqueous dispersion prepared using the cosmetic composition of the present invention (forming a bicontinuous structure) can easily disperse fullerenes in water, and has initial dispersibility. It was very excellent in transparency and dispersion stability. On the other hand, in the aqueous dispersion prepared using the cosmetic composition of Reference Example (with no bicontinuous structure formed), there is a tendency that fullerene can be dispersed in water, Even though it could be dispersed, the transparency and dispersion stability were insufficient.

The following cosmetics were produced using the cosmetic composition of the present invention. All of the resulting cosmetics can contain fullerenes easily and stably, skin cosmetics have excellent moisturizing properties, improve pore spreading, hair cosmetics improve hair damage, and give firmness. It was something to do.

Example 13 Hair mist component Blending amount (% by weight)
------------------------------------
Part A Cosmetic composition of Example 1 2.5
Purified water 20.0
Part B NanoRepair-V (Nippon Seika) 2.0
Hydrolyzed keratin 0.5
Methylparaben 0.2
Betaine 0.5
Citric acid 0.05
Purified water Total amount to be 100 ------------------------------------
(Preparation method)
Each of A and B parts was weighed and mixed uniformly, and then the two agents were mixed to make uniform.

Example 14 Hair Treatment Component Blending amount (% by weight)
------------------------------------
Part A isostearic acid 0.8
Polyricinoleic acid 0.5
Plandool-LG2 (Nippon Seika) 0.5
Neosolute-EHS (Nippon Seika) 1.0
Part B Cosmetic composition of Example 1 0.2
Propanediol 3.0
Steartrimonium chloride (70%) 1.5
Behenamidopropyldimethylamine 0.5
Cetanol 2.2
Stearyl alcohol 0.8
Hydrogenated rapeseed oil alcohol 0.5
Neopentyl glycol diethylhexanoate 0.8
Myristic acid PPG-3 benzyl ether 0.5
Jojoba seed oil 1.0
Glyceryl stearate 0.4
Propylparaben 0.1
Cocamide MEA 0.8
Caesarpinia spinosa hydroxypropyltrimonium chloride 0.1
Rice bran wax 0.5
Glycerin 1.0
Part C Methylparaben 0.1
Lactic acid 0.18
Hydrolyzed conchiolin 0.1
Panthenol 0.1
Polyquaternium-7 0.15
Purified water Total amount to be 100 -------------------------------------
(Preparation method)
Part A, which had been mixed and dissolved in advance, was added to part B and mixed uniformly at about 80 ° C. (part D). The part C set aside was heated to 80 ° C. and made uniform. The part D was gradually added to the part C with stirring and mixed uniformly, and then cooled to about 50 ° C.

Example 15 Hair treatment component Blending amount (% by weight)
------------------------------------
Part A Cosmetic composition of Example 1 0.2
Lanolin fatty acid 0.5
Plandool-MAS (Nippon Seika) 0.2
Neosolute-MP (Nippon Seika) 1.0
Ceramide 2 0.001
Ceramide 6 0.001
Part B stearoxypropyltrimonium chloride 1.0
Cetrimonium chloride 0.3
Dialkyl (C12-18) dimonium chloride 0.3
Stearyl alcohol 2.0
Cetanol 1.0
DPG 0.5
BG 1.0
Lactic acid 0.12
Hexa (hydroxystearic acid / stearic acid / rosinic acid)
Dipentaerythrityl 0.2
Polyglyceryl-6 polyricinoleate-6 1.0
Naphthalenesulfonic acid Na 0.5
Benzyl alcohol 0.4
Stearoxypropyldimethylamine 0.4
Behendimonium ethyl stearyl phosphate 0.05
Tristearin 0.5
CETEARETH-7 0.8
CETEARETH-25 0.3
Part C Purified water Amount to be 100 in total Phenoxyethanol 0.5
------------------------------------
(Preparation method)
Part A, which had been mixed and dissolved in advance, was added to part B and mixed uniformly at about 80 ° C. (part D). The part C set aside was heated to 80 ° C. and made uniform. The part D was gradually added to the part C with stirring and mixed uniformly, and then cooled to about 50 ° C.

Example 16 Hair treatment component Blending amount (% by weight)
------------------------------------
Part A Hydroxystearic acid 0.5
Plandool-LG1 (Nippon Seika) 0.3
Neosolute-MCT (Nippon Seika) 0.6
Neosolute-IOP (Nippon Seika) 3.0
Dextrin palmitate 0.5
Isostearoyl hydrolyzed collagen 0.2
Part B stearyl alcohol 2.0
Cetanol 1.2
Behentrimonium chloride 1.0
PEG-45M 0.8
Camellia seed oil 0.4
Hydroxyethylurea 0.5
Dicaprylyl carbonate 2.0
Squalane 0.1
Isocetes-10 0.5
Sunflower wax 0.8
Cocoyl Arginine Ethyl PCA 0.2
Phenoxyethanol 0.2
Tocopherol 0.05
Glycerin 1.3
DPG 2.2
Part C Cosmetic Composition of Example 1 0.2
Sorbitol 3.5
BG 1.0
Hydroxycellulose 0.07
Phenoxyethanol 0.2
Citric acid appropriate amount EDTA-2Na 0.01
Purified water Total amount of 100 parts D Polyquaternium-61 0.3
Tremoist-SL (Nippon Seika) 1.0
------------------------------------
(Preparation method)
Part A, which had been mixed and dissolved in advance, was added to part B and mixed uniformly at about 80 ° C. (part E). The part C set aside was heated to 80 ° C. and made uniform. The part E was gradually added to the part C with stirring and mixed uniformly, and then cooled to about 50 ° C. Furthermore, D part was added and mixed uniformly.

Example 17 Hair Treatment Component Blending amount (% by weight)
---------------------------------
Part A Plandool-DP (Nippon Seika) 1.0
Cetearyl alcohol 3.0
PPG-1 / PEG-1 stearamine 0.8
Behenamidopropyldimethylamine 1.0
Cetrimonium chloride (25%) 5.3
Ethylhexyl palmitate 1.0
Neosolute-DE (Nippon Seika) 1.0
Dimethicone (1 million cs) 1.0
Dimethicone (100cs) 3.0
Amodimethicone 1.0
Neopentyl glycol diheptanoate 2.0
Ethylhexyl isononanoate1.0
Hybrid sunflower oil 1.0
DPG 1.8
Glycerin 4.0
Phytosterols 0.1
Mineral oil 0.5
PEG-160M 0.5
Part B Cosmetic composition of Example 1 0.2
Lactic acid 0.3
Hydrolyzed starch 0.4
Hydroxypropyl methylcellulose 0.1
Hyaluronic acid Na 0.01
Purified water Total amount to be 100 ---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was added to a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and cooled.

Example 18 Treatment component Blending amount (% by weight)
---------------------------------
Part A NS-CIO (Nippon Seika) 1.0
Neosolute-IOP (Nippon Seika) 3.0
Stearyl alcohol 3.0
Behentrimonium chloride 1.0
Steartrimonium chloride 0.5
Stearamidopropyldimethylamine 0.1
Hydrogenated polyisobutene 1.0
Hydrogenated polydecene 0.6
Camellia seed oil 0.5
PPG-3 myristyl 0.5
Dextrin palmitate 0.3
Dicaprylyl ether 3.0
Dilauroyllysine Na 0.1
Ascorbyl dipalmitate 0.1
BG 3.0
Tocopherol 0.1
Phenoxyethanol 0.4
Part B Cosmetic composition of Example 1 0.2
Hydrogen carbonate Na 0.4
Purified water Total amount of 100 locust bean hydroxypropyltrimonium chloride 0.1
Lactic acid 0.05
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was added to a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and cooled.

Example 19 Treatment Ingredient Formulation Amount (wt%)
-----------------------------------
Part A Plandool-H (Nippon Seika) 0.5
DUB VCI-10 (Nippon Seika) 0.5
Neosolute-EHS (Nippon Seika) 0.7
Dimethicone (300cs) 2.0
Part B Behentrimonium Methosulfate 1.3
Cetrimonium chloride 0.3
Paraffin 1.0
Hydroxypropyltrimonium hyaluronate 0.2
Isostearic acid hydrogenated castor oil 1.0
Squalane 2.0
Tocopherol acetate 0.05
Diethyl sebacate 2.0
Candelilla wax 0.3
Apricot kernel oil 1.0
DPG 2.0
Propanediol 1.0
Benzyl alcohol 0.5
Glycerin 1.0
PEG-7 propyl heptyl ether 0.8
PEG-180M 0.3
Part C Cosmetic Composition of Example 1 0.2
Benzoic acid Na 0.3
EDTA-2Na 0.03
Purified water Total amount of 100 Polyquaternium-10 0.2
Tremoist-SL (Nippon Seika) 1.0
-----------------------------------
(Preparation method)
Part A and B, which had been mixed and dissolved in advance, were heated to about 80 ° C. and mixed uniformly (part D). The part C set aside was heated to about 60 ° C. and made uniform. The part C was gradually added to the part D with stirring and mixed uniformly, and then cooled to about 50 ° C.

Example 20 Shampoo Component Blending amount (% by weight)
---------------------------------
Part A Neosolute-IOP (Nippon Seika) 0.5
Plandool-MAS: (Nippon Seika) 0.1
Inulin stearate 1.0
Part B Laureth sulfate Na (27%) 20.0
Hydrogenated palm oil fatty acid PEG-200 glyceryl 1.0
Cocobetaine (25%) 8.0
Glycerin 1.0
Polysorbate 20 0.5
Palm oil fatty acid PEG-7 glyceryl 0.4
PPG-2 cocamide 0.3
PEG-60 hydrogenated castor oil 1.0
Bisabolol 0.01
Part C: Benzoic acid Na 0.4
Na chloride 0.5
Arginine 0.2
Purified water Amount D totaling 100 parts Cosmetic composition of Example 1 0.2
Polyquaternium-10 0.3
Purified water 9.7
---------------------------------
(Preparation method)
Part A and B, which had been mixed and dissolved in advance, were uniformly mixed at about 80 ° C. (part E). The part C set aside was heated to about 60 ° C. and made uniform. C. Part C was gradually added to part E with stirring and mixed uniformly, and then cooled to about 50.degree. Furthermore, D part was added and mixed uniformly.

Example 21 Dandruff Shampoo Component Blending amount (% by weight)
---------------------------------
Part A Cosmetic composition of Example 1 0.2
Lauroylmethylalanine Na (30%) 13.0
Cocamidopropyl betaine (30%) 20.0
Cocoa glutamic acid TEA (30%) 5.0
Cocamide DEA 1.0
Glycerin 1.0
Glyceryl caprylate 0.4
Glyceryl undecylenate 0.1
Isostearoyl hydrolyzed collagen 0.5
Neosolute-AquaS (Nippon Seika) 1.0
Distearate glycol 1.5
Part B: Benzoic acid Na 0.4
Na chloride 0.2
Purified water Total amount of 100 parts C Polyquaternium-7 0.3
Assembly extract 3.0
Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Polyquaternium-47 0.1
Piroctone olamine 0.1
Purified water 9.7
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was taken in a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and part C was added at about 60 ° C.

Example 22 Shampoo Component Compounding amount (% by weight)
---------------------------------
Part A Cosmetic composition of Example 1 0.2
Neosolute-EHS (Nippon Seika) 1.0
Plandool-LG2 (Nippon Seika) 1.0
Dextrin palmitate 0.5
Part B ammonium laureth sulfate 5.0
Laureth sulfate Na (25%) 10.0
Lauryl hydroxysultain (30%) 10.0
Lauric acid K 1.0
Distearate glycol 0.5
Toluenesulfonic acid 0.3
Stearoxypropyldimethylamine 0.5
PPG-17 0.3
Neopentyl glycol diethylhexanoate 0.4
Isodecyl glyceryl ether 0.4
Cocamide MEA 1.0
Laureth-4 0.3
Laureth-16 0.2
Steerless-6 0.2
Phenoxyethanol 0.3
Part C Malic acid 0.02
Methylparaben 0.2
Phosphoric acid 0.03
Benzoic acid Na 0.3
Purified water Total amount of 100 parts D Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Tremoist-SL (Nippon Seika) 3.0
Purified water 6.7
---------------------------------
(Preparation method)
Part A and B, which had been mixed and dissolved in advance, were uniformly mixed at about 80 ° C. (part E). The part C set aside was heated to about 60 ° C. and made uniform. C. Part C was gradually added to part E with stirring and mixed uniformly, and then cooled to about 50.degree. Furthermore, D part was added and mixed uniformly.

Example 23 Non-silicone shampoo Component Blending amount (% by weight)
---------------------------------
Part A PPG-3 caprylyl ether 2.0
Plandool-SUN (Nippon Seika) 0.3
Ceramide 3 0.001
Ceramide 5 0.004
Part B Cocoyl Methyl Taurine Na 3.0
Laureth sulfate Na (27%) 9.0
Lauryl hydroxysulfobetaine (30%) 7.0
Cocamide MEA 1.0
Polyquaternium-61 0.5
Neopentyl glycol diheptanoate 1.0
Distearate glycol 0.5
Polyglyceryl oleate-10 0.25
PEG-150 stearate 1.0
DPG 2.0
Phenoxyethanol 0.6
Part C Cosmetic Composition of Example 1 0.2
EDTA-2Na 0.05
Methylparaben 0.2
Benzoic acid Na 0.3
Purified water Total amount of 100 parts D Polyquaternium-10 0.5
Polyquaternium-7 0.2
Purified water 9.3
---------------------------------
(Preparation method)
Part A and B, which had been mixed and dissolved in advance, were uniformly mixed at about 80 ° C. (part E). The part C set aside was heated to about 60 ° C. and made uniform. C. Part C was gradually added to part E with stirring and mixed uniformly, and then cooled to about 50.degree. Furthermore, D part was added and mixed uniformly.

Example 24 Shampoo Component Compounding amount (% by weight)
---------------------------------
Part A Neosole-AquaS (Nippon Seika) 0.3
Cocoyl Methyl Taurine Na 3.0
Cocamidopropyl betaine (30%) 8.0
Laureth sulfate Na (27%) 10.0
Cocoamphoacetate Na (30%) 5.0
Cocamidomethyl MEA 1.0
Distearate glycol 0.5
DPG 1.3
Cocoylthreonine Na 1.0
Dilauroyl glutamate lysine Na 0.05
PPG-70 glyceryl 0.7
PEG-10 Dimethicone 1.0
Cocoyl Arginine Ethyl PCA 0.2
Phenoxyethanol 0.3
Part B Cosmetic composition of Example 1 0.2
EDTA-2Na 0.05
Methylparaben 0.2
Benzoic acid Na 0.3
Purified water Total amount of 100 parts C Polyquaternium-10 0.3
Polyquaternium-7 0.2
Locust bean hydroxypropyltrimonium chloride 0.1
Na chloride 0.3
Purified water 9.4
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was taken in a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and part C was added at about 60 ° C.

Example 25 Shampoo Component Compounding amount (% by weight)
---------------------------------
Part A Neosolute-MP (Nippon Seika) 0.5
Lauroyl sarcosine TEA (30%) 3.0
Cocoa glutamic acid TEA (30%) 8.0
Laureth sulfate Na (27%) 10.0
Palm nuclear fatty acid amidopropyl betaine (30%) 5.0
Cocamidomethyl MEA 1.0
Distearate glycol 0.5
Palm oil fatty acid PEG-7 glyceryl 0.3
Ascorbyl dipalmitate 0.2
Lauric acid PEG-2 1.3
Cocoyl Arginine Ethyl PCA 0.1
Phenoxyethanol 0.3
Part B Cosmetic composition of Example 1 0.2
EDTA-2Na 0.05
Methylparaben 0.2
Dehydroacetic acid 0.2
Benzoic acid Na 0.3
Purified water Total amount of 100 parts C Polyquaternium-10 0.5
Polyquaternium-49 0.1
Ethanol 3.0
Purified water 4.8
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was taken in a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and part C was added at about 60 ° C.

Example 26 Non-silicone shampoo Component Blending amount (wt%)
---------------------------------
Part A Setanol 0.3
Myristic acid 0.1
PEG-2 caprylylamine 1.0
Ammonium xylenesulfonate 1.0
Lauroamphoacetate Na (30%) 7.0
Laureth sulfate Na (27%) 10.0
Distearate glycol 0.5
Palm oil fatty acid PEG-7 glyceryl 0.3
PPG-3 caprylyl ether 1.5
Myristic acid PPG-3 benzyl ether 0.5
Dodecylbenzenesulfonic acid Na 2.0
Sunflower wax 0.01
Polyquaternium-64 0.5
Dimethicone (100cs) 0.1
Neosolute-AquaS (Nippon Seika) 0.3
PPG-7 0.5
Cetrimonium chloride (30%) 1.0
Poloxamer-407 0.8
Hydrogenated polydecene 0.2
Phenoxyethanol 0.3
Part B Cosmetic composition of Example 1 0.2
EDTA-2Na 0.05
Ethylenediamine disuccinic acid 3Na 0.1
Benzoic acid Na 0.3
Polyquaternium-10 0.1
Guar hydroxypropyltrimonium chloride 0.3
Hydroxypropyltrimonium hyaluronate 0.3
Purified water Total amount of 100 parts C Xanthan gum 0.1
Tremoist-TP (Nippon Seika) 0.05
Carbomer 0.1
Arginine 1.0
Hydroxide Na 0.05
Na chloride 0.7
Purified water 10.0
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was taken in a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and part C was added at about 60 ° C.

Example 27 Shampoo Component Compounding amount (% by weight)
---------------------------------
Part A Cosmetic composition of Example 1 0.2
Neosolute-Aqualio (Nippon Seika) 0.1
Lanolin fatty acid 0.1
Laureth sulfosuccinate 2Na (26%) 10.0
Lauroamphoacetate Na (30%) 7.0
Lauryl sulfate TEA (40%) 6.0
Laureth-2 1.0
Dioleic acid PEG-120 methyl glucose 1.0
Tetraoleic acid Solves-60 3.5
Caprylyl glucoside 0.3
Distearate glycol 0.5
PEG-2 cocamine 1.2
PEG-30 hydrogenated castor oil 0.5
Palm oil alkyl glucoside 1.0
Glyceryl oleate 0.8
Phenoxyethanol 0.3
Part B EDTA-2Na 0.05
Methyl isothiazolinone 0.005
Purified water Total amount of 100 parts C Polyquaternium-10 0.1
Guar hydroxypropyltrimonium chloride 0.3
Na chloride 0.3
Ascorbic acid 0.3
Hyaluronic acid Na 0.3
Purified water 19.3
---------------------------------
(Preparation method)
Part B was heated to about 80 ° C. and dissolved uniformly. Part A was taken in a separate container, heated and dissolved. Part B was gradually added to part A, mixed uniformly, and part C was added at about 60 ° C.

Example 28 Hair treatment component without washing away
------------------------------------
Part A Plandool-G (Nippon Seika) 0.1
DUB VCI-10 (Nippon Seika) 1.0
Part B Neosole-Aculio (Nippon Seika) 0.5
Cetrimonium chloride (25%) 1.1
Cation NH (Nippon Seika) 0.3
Elcalactone DES (Nippon Seika) 2.0
Neopentyl glycol diheptanoate 2.0
Glycerin 4.0
Phenoxyethanol 0.3
Part C Hydrolyzed keratin 0.1
Keratin 0.1
Hydrolyzed conchiolin 0.1
Panthenol 0.1
Hydroxypropyltrimonium hyaluronate 0.01
Hyaluronic acid crosspolymer Na 0.01
Polyquaternium-51 0.5
Part D Composition for Cosmetics of Example 1 2.5
Purified water Total amount to be 100 Hydroxyethyl cellulose 0.1
------------------------------------
(Preparation method)
Part A, which had been uniformly mixed in advance, was added to part B and heated to about 80 ° C. to dissolve (part E). In a separate container, part D was heated to about 80 ° C. and dissolved. While stirring D part to E part, it was gradually added and mixed uniformly, and then rapidly cooled (part F). C part was added to F part which became about 40 ° C. to make it uniform.

Example 29 Hair wax component Amount (% by weight)
-------------------------------------
Part A Plandool-DP (Nippon Seika) 2.0
Microcrystalline wax 4.0
Hydrogenated polyisobutene 5.0
Rice bran wax 3.0
Hydroxystearic acid 6.0
Glyceryl stearate 1.0
Isohexadecane 5.0
Dimethicone (10,000 cs) 1.0
PPG-3 caprylyl ether 2.0
Diisopropyl adipate5.0
Setes-2 6.0
Setes-20 0.5
BHT 0.05
Phenoxyethanol 0.6
Methylparaben 0.2
BG 3.0
Part B Cosmetic composition of Example 1 0.2
Hydroxide Na 0.2
Purified water Amount that totals 100 -------------------------------------
(Preparation method)
Part A and part B are each heated to about 80 ° C. and mixed uniformly. The part B is gradually added to the part A while stirring, and the mixture is uniformly mixed and then cooled.

Example 30 Hair wax component Blending amount (% by weight)
-------------------------------------
Part A Triethylhexanoin 1.0
Plandool-H (Nippon Seika) 3.0
Tri-hydrogenated glyceryl rosinate 1.0
Ethyl hexyl methoxycinnamate 2.0
Lanolin 1.0
Elcalactone MCT (Nippon Seika) 3.0
Ceramide 1 0.0001
Ceramide 2 0.01
Part B Candelilla Wax 1.0
DUB VCI-10 (Nippon Seika) 2.5
PPG-1 Behenez-15 5.0
Carnauba wax 4.0
Polyurethane-1 2.0
Glycerin 5.0
Silica 2.0
Na hydroxide (50% solution) 0.3
Part C Phenoxyethanol 0.6
Methylparaben 0.2
Purified water Amount D totaling 100 parts Cosmetic composition of Example 1 1.0
(Acrylates / Stearless Methacrylate-20) Copolymer 1.0
PEG-240 / decyltetradeceth-20 / HMDI) copolymer 0.75
Purified water 30.0
-------------------------------------
(Preparation method)
Part A previously mixed and dissolved was added to part B and mixed uniformly at about 80 ° C. (part E). The part C set aside was heated to about 60 ° C. and made uniform. C. Part C was gradually added to part E with stirring and mixed uniformly, and then cooled to about 50.degree. Furthermore, D part was added and mixed uniformly.

Example 31 Moose component Blending amount (% by weight)
---------------------------------
Cosmetic composition of Example 1 0.2
NS-CIO (Nippon Seika) 1.0
Ethanol 5.0
Polyethylene glycol oleyl ether (20) 1.0
Acrylic resin alkanolamine solution 3.0
Stearic acid diethylaminopropylamide 0.5
Pyrrolidone carboxylic acid 0.2
Preservatives, fragrance 1.0
Purified water Total amount to be 100 ---------------------------------
(Preparation method)
The above components were mixed, and the obtained base and LPG were mixed at a ratio of base: LPG = 92: 8 to obtain an injection-type mousse.

Example 32 Hair Cream Ingredient Amount (% by weight)
---------------------------------
Part A Cosmetic composition of Example 1 0.2
PPG-3 caprylyl ether 1.5
Neosolute-MCT (Nippon Seika) 0.6
Neosolu-Aculio (Nippon Seika) 1.0
Neosolute-Aqua (Nippon Seika) 0.8
Cetyl palmitate 3.0
Candelilla wax 4.0
Beeswax 2.0
Cetyl ethylhexanoate 2.0
Setes-7 2.0
Ceramide 0.1
Stearyl alcohol 1.5
PEG-8 0.8
Part B (Acrylates / alkyl acrylate (C10-30)) cross polymer 0.2
AMP 0.2
Hydrolyzed keratin 0.5
Purified water 10.0
Part C Hydroxide K 0.3
PG 0.5
Purified water Total amount to be 100 ---------------------------------
(Preparation method)
Part A was mixed at 80 ° C. Part C was heated to 80 ° C. and added to part A to emulsify (part D). After cooling to 50 ° C., part B was added to make uniform.

Example 33 Hair Treatment not Washed Ingredient Compounding amount (% by weight)
------------------------------------
Part A Neosolute-EHS (Nippon Seika) 1.4
Plandool-MAS (Nippon Seika) 1.0
Hydrolyzed keratin 0.01
Dextrin palmitate 2.0
Part B stearamidopropyldimethylamine 0.5
Stearyl alcohol 1.5
Myristyl alcohol 0.3
Phytocompo-pp (Nippon Seika) 0.2
Glycerin 4.0
Phenoxyethanol 0.2
Part C Cosmetic Composition of Example 1 0.2
Cetearamid ethyl dietium hydrolyzed rice protein 0.2
Hydrolyzed conchiolin 0.1
Part D Lactic acid 0.1
Glycerin 2.0
Purified water Total amount to be 100 -------------------------------------
(Preparation method)
Part A mixed and dissolved in advance was added to part B and heated to about 80 ° C. to dissolve (part E). In a separate container, part D was heated to about 80 ° C. to make it uniform. While stirring D part to E part, it was gradually added and mixed uniformly, and then rapidly cooled (part F). C part was added to F part which became about 40 ° C. to make it uniform.

Example 34 Hair oil component Amount (% by weight)
---------------------------------
Cosmetic composition of Example 1 0.2
Elcalactone DES (Nippon Seika) 2.0
Neosolute-MP (Nippon Seika) 10.0
Neosolute-EHS (Nippon Seika) 10.0
Neosolute-MCT (Nippon Seika) 20.0
PPG-3 caprylyl ether 2.0
Tocopherol 0.1
Propylparaben 0.05
Carnauba wax 0.1
Isododecane in a total amount of 100 --------------------------------
(Preparation method)
All ingredients were dissolved by heating and mixed.

Example 35 Whitening lotion component Blending amount (% by weight)
---------------------------------------
Part A Cosmetic composition of Example 1 2.0
Purified water 10.0
Part B Xanthan gum 0.05
BG 3.0
Purified water 20.0
Part C VC ethyl (Nippon Seika) 1.0
Purified water 5.0
Part D Tremoist-TP (Nippon Seika) 0.01
BG 4.0
Inositol 0.5
Glycyrrhizic acid 2K 0.05
Ethanol 3.0
Phenoxyethanol 0.2
Methylparaben 0.15
Citric acid 0.1
Amount of Na citrate pH 4.5 4.5 Amount of purified water Total amount of 100 -------------------------------- -------
(Preparation method)
Part B was mixed to prepare a viscous liquid. Part A was warmed to 50 ° C. and slowly added to Part B with stirring. Furthermore, C part and D part mixed beforehand were added, and it was set as the uniform liquid.

Example 36 Whitening lotion component Blending amount (% by weight)
---------------------------------------
Part A Cosmetic composition of Example 1 3.0
DPG 3.0
Glycerin 1.0
Part B purified water 20.0
Part C Tranexamic acid (Nippon Seika) 2.0
Purified water 20.0
Part D Neosolue-Aculio (Nippon Seika) 0.5
Niacinamide 0.3
Betaine 1.0
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total amount to be 100 ---------------------------------------
(Preparation method)
Part A was mixed and slowly added to Part B with stirring at about 50 ° C. to prepare a dispersion. Furthermore, C part and D part mixed beforehand were added, and it was set as the uniform liquid.

Example 37 Moisturizing lotion component Blending amount (% by weight)
--------------------------------------
Part A Cosmetic composition of Example 1 1.0
Diglycerin 3.0
Hydrolyzed hyaluronic acid 0.01
Arginine 0.05
Part B purified water 20.0
Part C Neosolue-AquaS (Nippon Seika) 1.0
Betaine 0.5
Pullulan 0.5
Hyaluronic acid Na 0.01
Hydroxyethyl cellulose 0.03
Carbomer 0.05
Arginine 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total amount to be 100 --------------------------------------
(Preparation method)
Part A was mixed and slowly added to Part B with stirring to prepare a dispersion. Furthermore, it added to the C part mixed previously, and was set as the uniform liquid.

Example 38 Moisturizing lotion component Blending amount (% by weight)
---------------------------------------
Part A Cosmetic composition of Example 1 2.0
Diglycerin 3.0
Astaxanthin 0.01
Ubiquinone 0.05
Part B purified water 20.0
Part C Neosolue-AquaS (Nippon Seika) 1.0
PEG / PPG / polybutylene glycol-8 / 5/3 glycerol 0.5
Glucosylceramide 0.5
Glucosyl rutin 0.01
Polyquaternium-51 0.5
Acetyl hexapeptide-8 0.001
Hydrolyzed collagen 0.05
Carbomer 0.05
Arginine 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total amount to be 100 ---------------------------------------
(Preparation method)
Part A was mixed and part B was slowly added with stirring to prepare a dispersion. Furthermore, it added to the C part mixed previously, and was set as the uniform liquid.

Example 39 Gel lotion component Blending amount (% by weight)
------------------------------------
Part A Phytocompo-PP (Nippon Seika) 1.0
Glycerin 5.0
Sorbitol solution (70%) 5.0
Glyceryl behenate 0.8
Stearic acid 0.3
PEG-10 Dimethicone 0.4
Part B Composition for Cosmetics of Example 1 3.0
Purified water 20.0
Part C Phenoxyethanol 0.3
Pullulan 0.2
Ethylhexyl glycerin 0.2
Poly HEMA glucoside 0.05
Polymethacryloyl lysine 0.05
Crystalline cellulose powder 0.1
Locust bean gum 0.03
Hydroxyethyl cellulose 0.05
Hyaluronic acid Na 0.01
Carbomer 0.06
Hydroxide K 0.05
Purified water Total amount to be 100 -------------------------------------
(Preparation method)
Part A was heated to about 70 ° C. and dispersed uniformly. Part C was mixed, stirred well, homogenized, and heated to about 70 ° C. Part B was stirred with a propeller to prepare a dispersion. C part was added to A part, it stirred using the homomixer at about 70 degreeC, it cooled to about 40 degreeC, and the liquid mixture of B part was added.

Example 40 Transparent gel component Blending amount (% by weight)
--------------------------------------
Part A Cosmetic composition of Example 3 0.5
Glycerin 3.0
Purified water 30.0
Part B PEG-4000 0.2
Methyl Gluces-10 1.0
Phenoxyethanol 0.3
Pyridoxine hydrochloride 0.05
Ethylhexyl glycerin 0.2
Hydroxyethyl cellulose 0.05
Tremoist-TP (Nippon Seika) 0.01
Hydrolyzed collagen 0.01
Purified water Total amount of 100 parts C (dimethyl taurate ammonium acrylate / vinyl pyrrolidone) copolymer 0.05
(Acrylates / alkyl acrylate (C10-30)) cross polymer 0.15
Arginine 0.25
Purified water 30.0
---------------------------------------
(Preparation method)
Part A was stirred with a propeller to prepare a dispersion. Part C was a viscous liquid when mixed. Part B was mixed to obtain a uniform liquid. Part A and part B were added to part C to make it uniform.

Example 41 Moisturizing emulsion component Blending amount (% by weight)
-----------------------------------
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-PP (Nippon Seika) 1.0
Hydrogenated lysolecithin (main refinement) 0.1
Part B IOTG (Nippon Seika) 3.0
LUSPLAN SR-DM4 (Nippon Seika) 0.5
Dimethicone (100CS) 5.0
Hydrogenated polyisobutene 3.5
Cetostearyl alcohol 1.0
Aralkyl alcohol 0.1
Jojoba alcohol 3.0
Kimyl alcohol 0.3
Serakil alcohol 0.1
Hexyldecanol 0.5
Part C Cosmetic composition of Example 1 2.0
Purified water 20.0
Part D (hydroxyethyl acrylate / acryloyl dimethyltaurine Na) copolymer 0.2
Tremoist-TP (Nippon Seika) 0.03
Carbomer 0.1
Purified water 30.0
Part E Neosolue-AquaS (Nippon Seika) 0.5
Polyquaternium-51 1.0
Ascorbyl glucoside 1.0
Potassium hydroxide 0.2
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total amount to be 100 ------------------------------------
(Preparation method)
Part A, part B and part E were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed with a propeller (room temperature) to prepare a dispersion. Part D was mixed and stirred to give a viscous liquid. After adding part B while stirring part A with a homodisper, part E was added and emulsified. At about 50 ° C, C and D parts were added, and the mixture was stirred and cooled to about 40 ° C.

Example 42 UV emulsion component Blending amount (% by weight)
--------------------------------------
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-C5 (Nippon Seika) 1.0
Cosmetic composition of Example 2 1.5
Part B Neosolute-DE (Nippon Seika) 5.0
Neosolute-MP (Nippon Seika) 2.0
DUB VCI-10 (Nippon Seika) 2.0
Plandool-ISS (Nippon Seika) 0.8
Dimethicone 5.0
Ethyl hexyl methoxycinnamate 5.0
Dimethoxybenzylidene dioxoimidazolidine propionate ethylhexyl 0.5
t-Butylmethoxydibenzoylmethane 0.5
Synoxate 1.0
Dihydroxydimethoxybenzophenone 0.5
Tetrahydroxybenzophenone 0.1
Methyl bis (trimethylsiloxy) trimethoxycinnamate
Silylisopentyl 0.5
2-Ethylhexyl paradimethylaminobenzoate 1.0
Bisethylhexyloxyphenol methoxyphenyl triazine 1.0
Diethylaminohydroxybenzoyl hexyl benzoate 1.0
Ethylhexyl triazone 1.0
3- (4′-Methylbenzylidene) -d, l-camphor 1.0
Methyl 2,5-diisopropylcinnamate1.0
Octyl salicylate 2.0
Homomentil salicylate 1.5
1- (3,4-Dimethoxyphenyl) -4,4-dimethyl-1,3-pentanedione 1.0
Amyl paradimethylaminobenzoate 0.5
Polyglyceryl pentastearate-10 1.0
N-lauroyl sarcosine isopropyl 2.0
Isostearyl alcohol 1.0
Stearyl alcohol 0.5
2-octyldodecanol 1.0
Dimer diol 0.5
Benzyl alcohol 0.5
Isostearic acid 1.0
Erucic acid 1.0
Rice wax 0.1
Ceresin 0.1
Paraffin wax 0.1
Microcrystalline wax 0.1
Polyethylene 0.1
Safflower oil 0.5
Olive oil 0.5
Castor oil 0.3
Tea oil 0.3
Evening primrose oil 0.3
Wheat germ oil 0.3
Part C Hydroxyethylcellulose 0.2
Stearoxyhydroxypropylmethylcellulose 0.8
Tremoist-TP (Nippon Seika) 0.03
Purified water 20.0
Part D Neosolue-AquaS (Nippon Seika) 0.5
VC ethyl (Nippon Seika) 0.5
Arbutin (Nippon Seika) 0.5
Phenoxyethanol 0.2
Methylparaben 0.15
Sodium dihydroxydimethoxybenzophenone disulfonate 0.5
Phenylbenzimidazolazosulfonic acid 1.0
Hydroxide Na 1.0
Purified water Total amount to be 100 ---------------------------------------
(Preparation method)
Part A, part B and part D were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to give a viscous liquid. After adding part B while stirring part A with a homomixer, part D was added and emulsified. At about 50 ° C., part C was added, and the mixture was stirred and cooled to about 40 ° C.

Example 43 UV emulsion component Blending amount (% by weight)
---------------------------------------
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-PP (Nippon Seika) 1.0
Part B Plandool-SUN (Nippon Seika) 1.0
Dimethicone 10.0
Ethyl hexyl methoxycinnamate 7.0
t-Butylmethoxydibenzoylmethane 1.5
Bisethylhexyloxyphenol methoxyphenyl triazine 1.0
Diethylaminohydroxybenzoyl hexyl benzoate 0.5
Ethylhexyl triazone 1.0
Homosalate 0.5
4- (2-β-Glucopyranosiloxane) propoxy-2-hydroxybenzophenone 0.7
2-Hydroxy-4-methoxybenzophenone 0.3
Dimethyldiethylbenzalmalonate 0.5
Part C Hydroxyethylcellulose 0.2
Stearoxyhydroxypropylmethylcellulose 0.8
Tremoist-TP (Nippon Seika) 0.03
Purified water 20.0
Part D Cosmetic composition of Example 4 1.0
Purified water 15.0
Part E Neosolue-AquaS (Nippon Seika) 0.5
VC ethyl (Nippon Seika) 1.0
Tranexamic acid 1.0
Glyceryl ascorbic acid 0.5
Arbutin 0.5
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount F totaling 100 Titanium oxide (silica treatment) 1.0
Zinc oxide (silica treatment) 2.0
-----------------------------------------
(Preparation method)
Part A, part B and part E were mixed, heated to about 70 ° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to give a viscous liquid. Part D was mixed by propeller stirring to obtain a dispersion. After adding part B while stirring part A with a homodisper, part E was added and emulsified. After cooling, at about 50 ° C., D part and F part were added and stirred to cool to about 40 ° C.

Example 44 Skin care cream component Blending amount (% by weight)
--------------------------------------
Part A Plandool-ISS (Nippon Seika) 1.0
Jojoba oil 2.0
Plandool-H (Nippon Seika) 1.0
Neosolute-MCT (Nippon Seika) 5.0
LUSPLAN DD-DHR (Nippon Seika) 3.0
Propylene glycol monostearate 0.6
Behenyl alcohol 2.0
Ethylparaben 0.1
Liquid isoparaffin 0.5
Carnauba wax 0.3
Corn oil 0.3
Rapeseed oil 1.0
Sunflower oil 1.0
Wheat germ oil 1.0
Linseed oil 0.1
Cottonseed oil 0.1
Soybean oil 0.1
Cholesteryl nonanoate 0.1
Cholesteryl stearate 0.1
Cholesteryl isostearate 1.0
Cholesteryl oleate 0.1
Cholesteryl 12-hydroxystearate 0.1
Long-chain branched fatty acid cholesteryl 0.3
Octyldodecyl myristate 1.0
Daimerlinoleic acid hydrogenated castor oil 1.0
Hydroxyalkyl dimer linoleyl ether 1.0
Phenyltrimethicone 1.0
Diphenyl dimethicone 1.0
Methyl hydrogen polysiloxane 1.0
Polyglyceryl-3 polydimethylsiloxyethyl dimethicone 0.5
Polyoxyethylene methylpolysiloxane copolymer 1.0
Tannin 0.01
Sesamin 0.01
Protoanthocyanidin 0.01
Grab lysine 0.01
Grablen 0.01
Liquiritin 0.01
Isoliquitin 0.01
Lactoferrin 0.01
Gingerall 0.01
Gingerol 0.01
Part B (acryloyldimethyltaurine /
Methenic acid behenes-25) copolymer 0.2
(Acryloyldimethyltaurate ammonium / VP) copolymer Purified water 20.0
Part C Composition for Cosmetics of Example 2 0.5
Composite-PC (Nippon Seika) 1.5
LP70H (Nippon Seika) 0.05
Hydrogenated egg yolk lecithin 0.1
Stigmasterol 1.0
Stigmasterol 1.0
Dihydrocholesterol 0.1
Lanosterol 0.1
Dihydrolanosterol 0.1
Glycerin 7.0
DPG 7.0
Menthol 0.1
Camphor 0.1
Tocopherol ferulate 0.1
Tocopherol phosphate 0.1
Polyglyceryl laurate-10 0.5
Tocotrienol 0.1
Part D Citric acid 0.07
Sodium citrate appropriate amount EDTA-2Na 0.1
Tranexamic acid (Nippon Seika) 2.0
Methylparaben 0.1
Purified water Total amount to be 100 --------------------------------------
(Preparation method)
Part A was mixed and heated to about 70 ° C. to dissolve evenly. Part B was mixed and stirred to give a viscous liquid. Part C was mixed, heated to about 70 ° C., and dispersed uniformly. Part D was mixed and heated to about 70 ° C. and dissolved uniformly. A part A was added to part C while stirring with a homogenizer, and then part D was added to emulsify. At about 50 ° C., part B was added and stirred to dissolve uniformly.

Example 45 Skin Care Cream Ingredient Amount (% by weight)
------------------------------------
Part A Plandool-SUN (Nippon Seika) 1.0
Neosolu-Aculio (Nippon Seika) 1.5
Neosolute-EHS (Nippon Seika) 8.0
Plandool-ISS (Nippon Seika) 1.0
Diisopropyl sebacate (IPSE: Nippon Seika) 2.0
Batyl isostearate 2.0
Shea fat 3.0
Cyclopentasiloxane 5.0
Isostearyl pivalate 0.1
NS-408 (Nihon Seika) 0.1
Ethylparaben 0.2
Stearyl alcohol 3.5
Dimethicone 1.0
Cyclomethicone 3.0
Tocopherol 0.1
Ascorbyl tetrahexyldecanoate 3.0
Tocopheryl ascorbyl phosphate 2.0
Placenta extract 1.0
Oryzanol 0.3
Phytosphingosine 0.0001
Ubiquinone 0.03
Carotene 0.05
Lycopene 0.01
Astaxanthin 0.01
Lutein 0.01
Peanut oil 0.1
Rice bran oil 1.0
Hydrogenated castor oil 0.3
Jojoba oil 2.0
Orange Raffy Oil 1.0
Liquid lanolin (Nippon Seika) 1.0
Purified lanolin (Nippon Seika) 1.0
Bell Paul L-50 (Nippon Seika) 1.0
Lanolin alcohol (Nippon Seika) 0.3
Lanolin acetate 0.1
Cholesteryl acetate 0.1
Polyglyceryl triisostearate-2 1.0
PEG-60 glyceryl isostearate 1.5
Stearic acid PG (SE) 1.0
Glyceryl stearate (SE) 1.0
Octocrylene 0.05
Part B Tremoist-TP (Nippon Seika) 0.05
Tuberose polysaccharide 0.01
Water-soluble collagen 0.05
Hydrolyzed collagen 0.5
2-Methacryloyloxyethyl phosphorylcholine
Butyl methacrylate copolymer solution 0.05
(HEMA glucoside / ethyltrimonium methacrylate methacrylate) copolymer (20%, Nippon Seika) 0.4
Glutathione 0.3
4- (4-Hydroxyphenyl) -2-butanol 1.5
Butyl resorcinol 1.5
Arbutin (Nippon Seika) 3.0
Ascorbyl phosphate Mg 1.0
Part C BG 5.0
Glycerin 7.0
DPG 2.0
Pyrosulfite Na 0.1
Imidazolinium urea 0.1
Polyvinylpyrrolidone 0.1
Pullulan 0.1
Polyvinyl alcohol 0.1
Dehydroacetic acid 0.1
PEG-30 1.0
Diglycerin 1.0
Polyglycerin 1.0
Penteto acid 5Na 0.05
Phosphoric acid, Na phosphate Appropriate amount Purified water Amount that makes a total of 100 Part D Cosmetic composition of Example 1 1.0
Purified water 15.0
------------------------------------
(Preparation method)
Part A was heated to about 70 ° C. and dissolved uniformly. Part C was heated to about 70 ° C. and dispersed. Part D was thoroughly stirred with a propeller to prepare a dispersion. While stirring with a homomixer at about 70 ° C., part A was gradually added to part C and mixed uniformly after emulsification, cooled to about 40 ° C., and parts B and D were added and mixed uniformly.

Example 46 Skin Care Cream Ingredient Formulation Amount (% by weight)
------------------------------------
Part A Glycerin 5.0
PG 2.0
Phytocompo-C (Nippon Seika) 1.0
Part B Plandool-LG2 (Nippon Seika) 0.5
Plandool-LG1 (Nippon Seika) 0.5
LUSPLAN DD-DA7 (Nippon Seika) 0.1
Plandool-MAS (Nippon Seika) 0.5
Glyceryl amidomethacrylate /
Stearyl methacrylate copolymer 0.05
Olive oil 3.5
Macadamia nut oil 4.5
Hydrogenated vegetable oil 3.0
Dimethicone (100cs) 0.5
Ethyl hexyl methoxycinnamate 2.0
Ethylparaben 0.15
Lanolin fatty acid octyldodecyl 1.0
Isostearic acid hydrogenated castor oil 0.5
Ethyl oleate 3.0
Avocado oil fatty acid ethyl 2.0
Isopropyl palmitate 2.0
Isopropyl isostearate 1.0
Methylheptyl laurate 3.0
Methyl heptyl myristate 3.0
Methylheptyl palmitate 3.0
Methylheptyl isostearate 3.0
Diethyl sebacate 1.0
Diisopropyl sebacate 1.0
Diisopropyl adipate1.0
Diisobutyl adipate 1.0
Dioctyl succinate 1.0
Triethyl citrate 1.0
Cetyl lactate 1.0
Diisostearyl malate 5.0
γ-docosalactone 0.2
Glyceryl trioleate 0.1
Glyceryl triisostearate0.1
Glyceryl diisostearate0.1
Tri (caprylic acid / capric acid / myristic acid /
Stearic acid) glyceryl 0.1
(Behenic acid / eicosanedioic acid) Glyceryl 0.1
Trimethylolpropane trioctanoate 0.5
Neopentyl glycol dicaprate 1.0
Perfluorodecane 1.0
Perfluorooctane 1.0
5,5′-Dipropyl-biphenyl-2,2′-diol 0.3
Oil-soluble chamomile extract 0.3
Oil-soluble licorice extract 0.05
Retinol 0.1
Retinol acetate 0.1
Retinol palmitate 0.1
Pyridoxine dioctanoate 0.1
Pyridoxine dipalmitate 0.1
Tocopherol nicotinate 0.1
Tocopherol acetate 0.1
Tocopherol linoleate 0.1
Glycyrrhetinic acid 0.05
Hinokitiol 0.05
Indomethacin 0.05
Hydrocortisone acetate 0.1
Prednisone 0.1
Diphedramine hydrochloride 0.1
Borneol 0.1
Cephalanthin 0.001
Photosensitive element 301 0.001
Photosensitive element 401 0.001
Cetyl tranexamate 2.0
Part C Composition for Cosmetics of Example 1 2.5
Ascorbyl tetrahexyldecanoate 1.0
Purified water 10.0
Part D Methylparaben 0.1
Phenoxyethanol 0.2
Xanthan gum 0.1
(Acrylates / alkyl acrylate (C10-30)) Cross polymer 0.2
(Hydroxyethyl acrylate /
Acryloyldimethyltaurine Na) copolymer 0.2
Arginine 0.3
Purified water Total amount to be 100 -------------------------------------
(Preparation method)
Part A was heated to about 70 ° C. and dispersed uniformly. Part B was heated to about 80 ° C. and dissolved uniformly. Part C was stirred well to prepare a dispersion. While part A was stirred with a homodisper, part B was added and dispersed (part E). Further, D part was added to E part with stirring. Stir and cool to about 40 ° C.

Example 47 Skull Propaction Component Blending amount (% by weight)
------------------------------------
Part A Pentylene glycol 2.0
Glycyrrhetinic acid 0.05
PPG-5 phytosterol 0.1
Cosmetic composition of Example 2 2.5
Part B Methylparaben 0.1
Purified water 50.0
Part C Glycerin 4.0
Maltitol 0.5
Ethanol 10.0
Neosolu-Aculio (Nippon Seika) 1.0
Tocopherol acetate 0.05
Menthol 0.1
Menthoxypropanediol 0.05
Betaine 0.2
Carrot extract 0.1
Assembly extract 0.1
Japanese cypress rafji root extract 0.003
Pyridoxine hydrochloride 0.05
Panthenol 0.1
PCA-Na 0.1
Purified water Total amount to be 100 ------------------------------------
(Preparation method)
Each component was measured and mixed uniformly. Part A was added to part B to prepare a dispersion. Further, C part was added with stirring to make uniform.

Example 48 Skull Propaction Component Blending amount (% by weight)
------------------------------------
Part A Glycerin 2.0
Cosmetic composition of Example 5 0.3
Purified water 10.0
Part B Neosole-AquaS (Nippon Seika) 0.5
Nicotinamide 1.0
Dipotassium glycyrrhizinate 0.1
VC ethyl (Nippon Seika) 0.3
Hyaluronic acid Na 0.01
Tremoist-SL (Nippon Seika) 0.5
Caprylyl proline 0.3
Raffinose 0.2
Arginine 0.5
Serine 0.1
Glycine 0.1
Purified water 50.0
Part C ethanol 10.0
Methylparaben 0.1
Menthol 0.1
Menthoxypropanediol 0.1
Ethyl dicarboethoxy pantothenate 0.2
Camphor 0.1
Carrot extract 1.0
Assembly extract 1.0
Glycosyl trehalose 0.5
Purified water Total amount to be 100 -------------------------------------
(Preparation method)
Part A was stirred with a propeller to prepare a dispersion. Each component of B part and C part was measured and mixed uniformly. After adding B part to A part and making it uniform, C part was added and made uniform.

Example 49 Body shampoo Component Blending amount (% by weight)
---------------------------------
Part A Cosmetic composition of Example 2 0.3
Purified water 10.0
Part B Neosole-AquaS (Nippon Seika) 0.5
Cocoyl Methyl Taurine Na 10.0
Lauroyl hydrolyzed silk Na 6.0
Lauroylmethylalanine Na 10.0
Cocoamphoacetate Na (30%) 4.0
Cocamidopropyl betaine (30%) 10.0
Olefin (C14-16) sulfonic acid Na 5.0
Polyquaternium-10 1.3
Guar hydroxypropyltrimonium chloride 0.8
Acetyl hyaluronic acid Na 0.02
Cocamide DEA 3.0
Glycerin 5.0
Methylparaben 0.2
Purified water Total amount to be 100 ---------------------------------
(Preparation method)
Part A was stirred and mixed with a propeller to prepare a dispersion. Part B was weighed and heated to about 80 ° C. and mixed uniformly. Part B was cooled with stirring and part A was added at 40 ° C.

Example 50 Hairist component Blending amount (% by weight)
------------------------------------
Part A Cosmetic Composition of Example 1 2.5
Purified water 20.0
Part B Neosole-Aculio (Nippon Seika) 0.5
Betaine 0.5
Sea salt 0.1
Tremoist-SL (Nippon Seika) 0.3
Purified water Total amount of 50 parts C Squalane 25.0
Neosolue-MCT (Nippon Seika) Total amount of 50 olive oil 5.0
Tocopherol 0.05
Plandool-SUN (Nippon Seika) 1.0
------------------------------------
(Preparation method)
Each of A and B parts was weighed and mixed uniformly, and then the two agents were mixed to make uniform. Furthermore, C part which was uniformly mixed was added to obtain a liquid that separated into two phases.

In the above formulation, details of the components described by the product name are as follows.
○ Plandool-H: Dimer linoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl)
○ Plandool-S: Dimer linoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl)
* Plandool-G: Dimer dilinoleic acid dimer dilinoleyl bis (behenyl / isostearyl / phytosteryl)
〇Plandool-DP: Bisdiglyceryl polyacyl adipate-2
〇 Plandool-ISS: Phytosteryl isostearate 〇 Plandol-SUN: Sunflower seed oil fatty acid phytosteryl 〇 Plandool-MAS: Macadamia nut oil fatty acid phytosteryl 〇 Plandool-LG1: Lauroyl glutamate di (phytosteryl / octyldodecyl / behenyl)
〇 Plandool-LG2: dilauroyl glutamate (phytosteryl / octyldodecyl)
○ Plandool-LG3: dilauroyl glutamate (phytosteryl / octyldodecyl / behenyl)
〇 Plandool-LG4: dilauroyl glutamate (phytosteryl / octyldodecyl / behenyl)
〇LUSPLAN DD-IS: Dimerostearic acid dimer dilinoleyl 〇 LUSPLAN PI-DA: Dimer dilinoleic acid di (isostearyl / phytosteryl)
O LUSPLAN DD-DHR: Dimer dilinoleic hydrogenated rosin condensate O LUSPLAN DD-DA5: Dimer dilinoleic acid dimer dilinole O LUSPLAN DD-DA7: Dimer dilinoleic acid dimer dilinole O LUSPLAN SR-DM4: Dai Dimerlinoleyl merlinoleate, tri (caprylic acid / capric acid) glyceryl O LUSPLAN SR-DP4: dimer dilinoleic acid dimer dilinoleyl, tetraisostearate pentaerythrityl O Neosolue-Aqulio: bisethoxydiglycol cyclohexanedicarboxylate ○ Neosolue-Aqua: (eicosanedioic acid / tetradecanedioic acid) polyglyceryl-10, glycerin ○ Neosolue-AquaS: (eicosanedioic acid / Tradecanedioic acid) polyglyceryl-10, glycerin o Neosolue-MP: dineopentanoic acid methylpentanediol o Neosole-DE: dineopentanoic acid diethylpentanediol o Neosolue-IOP: palmitate ethylhexyl o Neosole-EHS: diethylhexyl sebacate o PCosite : Hydrogenated lecithin, cholesterol o Phytocompo-PP: hydrogenated lecithin, phytosterols o Phytocompo-C: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3, ceramide 6II
* Phytocompo-C5: hydrogenated lecithin, phytosterols, ceramide 2, ceramide 3, ceramide 6II
○ Phytocompo-SP: hydrogenated lecithin, phytosterols, BG, glycerin ○ LP70H: hydrogenated lysolecithin (Nippon Seika)
○ Tremoist-TP: white jellyfish polysaccharide ○ Tremoist-SL: white jellyfish polysaccharide aqueous solution (1%)
○ YOFCO MAC: Macadamia nut oil fatty acid cholesteryl ○ Cation NH: Quotanium-33
〇 Elcalactone DES: γ-docosalactone, diethyl sebacate 〇 Elcalactone MCT: γ-docosalactone, tri (caprylic acid / capric acid) glyceryl 〇 NanoRepair-CMC5: Ceramide 1, Ceramide 2, Ceramide 3, Ceramide 5, Ceramide 6. Cholesterol, Quotanium-33, etc. NS-408: Tetraethylhexanoic acid pentaerythrityl Belpol L-50: PEG-50 Lanolin

　値が大きいほど、色が変化していることを示しており、実施例１の製剤１は、製剤１を塗布しないものと比較して髪の色の退色を防ぐことが明らかとなった。特に10回のダメージ処理後の退色抑制効果は、無処置及びフラーレンを除いた製剤２と比較して顕著であった。 Example 51
About the composition for cosmetics of Example 1, the fading suppression effect of hair was confirmed.
(Materials used)
・ Human hair: Gray hair (Buelux Co., Ltd.)
・ Dye-related: Wellabreach cream, Cholestone Perfect 14/45, Welloxon Perfect (P & G)
-Formulation prepared from the cosmetic composition of Example 1 excluding fullerene-Formulation prepared from the cosmetic composition of Example 1 (Preparation of formulation)
<Preparation of Formulation 1 of Example 1>
0.5 g of the cosmetic composition of Example 1 was dissolved in 49.5 g of water to obtain Formulation 1.
<Preparation of Formulation 2 Excluding Fullerene from Example 1>
0.5 g of the composition obtained by removing fullerene from the cosmetic composition of Example 1 was dissolved in 49.5 g of water to obtain Formulation 2.
(Processing method)
-Bleaching treatment The bleaching treatment was performed twice for 3 bundles of white hair.
Wellabreach cream and Welloxon Perfect were mixed 1: 2 and applied to the hair. After coating, the solution was left for about 40 minutes, rinsed with hot water, and then shampooed twice.
-Hair dyeing treatment Cholestone Perfect 14/45 and Weloxone Perfect were mixed well at 1: 2, and then applied to the bleached hair bundle. After leaving for 30 minutes, it was shampooed and dried with a dryer.
・ Damage treatment After washing the hair bundle, towel drying, spraying the formulation, drying it completely with a dryer, lightly spraying water, and then repeating UVB (about 5 mW / cm ² ) 10 minutes once, dyeing the hair Damaged the hair bundle. For no treatment, towel drying was followed by dryer drying.
・ Measurement (Spectro Photometer SE-7700, Nippon Denshoku Industries)
Six colors (root, middle, hair tips on the front and back) were measured for one hair bundle, and the average value was used.
After dyeing, the damage was measured at the first, fifth, and tenth damage. ΔE was measured from the Lab value immediately after hair dyeing and the Lab after damage to observe how much the color changed.
The results are shown in Table 6 and FIG.

It has been shown that the larger the value, the more the color is changed, and the formulation 1 of Example 1 has been shown to prevent hair color fading compared to the formulation 1 to which the formulation 1 is not applied. In particular, the effect of suppressing discoloration after 10 damage treatments was remarkable as compared with Formulation 2 excluding no treatment and fullerene.

Example 52
It is known that when hair is damaged by oxidation, the SS bond of cystine is oxidized to produce cysteic acid. For this reason, about the composition for cosmetics of Example 1, the quantity of the cysteic acid in the hair produced by an ultraviolet-ray was quantified. Human black hair (Beaulux Co., Ltd.) was washed with a 1% aqueous sodium lauryl sulfate solution, then washed with water and air dried. After cutting to about 5 cm and fixing to the holder, the infrared absorption spectrum was measured, and the ratio of the absorption wavelength of cysteic acid residue (1040 cm ^-1 ) to the absorption wavelength of amide (1634 cm ^-1 ) was calculated (Affinity -1, DuraSamplIR II, Shimadzu Corporation). Thereafter, water or the aqueous solution of Example 1 diluted to 5% was applied and completely dried with a dryer. The hair was irradiated with ultraviolet rays (about 300 J / cm ² , 70 hours) under a UVB lamp. Then, it was made to wash and dry, and the infrared absorption spectrum was measured again. It was confirmed in advance that this condition had no effect on the spectrum due to the formulation application of Example 1.
As a result, as shown in FIG. 2, in the case of only water treatment, the absorption of S = O indicating cysteic acid increased after UV irradiation, whereas the amount of cysteic acid in the aqueous solution (5%) treated hair of Example 1 It was confirmed that there was no change. This result revealed that the preparation of Example 1 can effectively suppress oxidative damage to hair due to ultraviolet rays.

Claims (8)

A cosmetic composition comprising the following components (A) to (E):
(A) Oil agent in which 0.001 to 0.3% by weight of fullerene is dissolved (B) Nonionic surfactant (C) Polyhydric alcohol (D) Oil agent (E) Water The cosmetic composition according to claim 1, which has a bicontinuous structure. When adding a solution in which a water-soluble pigment is dissolved in water and adding a solution in which an oil-soluble pigment is dissolved in oil, the hue of each pigment is uniformly colored. 3. The cosmetic composition according to 1 or 2. The content of component (A) is 1 to 20% by weight, the content of component (B) is 15 to 45% by weight, the content of component (C) is 10 to 35% by weight, and the content of component (D) is The cosmetic composition according to any one of claims 1 to 3, wherein the composition is 5 to 30% by weight and the content of the component (E) is 10 to 40% by weight. The oil agent other than fullerene constituting the component (A) is one or more selected from lactone derivatives and ester oils represented by the following general formula (1): 4. The cosmetic composition according to any one of 4 above.

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms) The nonionic surfactant of component (B) is one or more selected from polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene fatty acid ester and polyoxyethylene alkyl ether The cosmetic composition according to any one of claims 1 to 5, wherein there are two or more kinds. A cosmetic in which the cosmetic composition according to any one of claims 1 to 6 is dispersed in an aqueous medium. A hair cosmetic in which the cosmetic composition according to any one of claims 1 to 6 is dispersed in an aqueous medium.

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