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WO2018171882A1 - Nanoparticules magnétoluminescentes - Google Patents

Nanoparticules magnétoluminescentes Download PDF

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Publication number
WO2018171882A1
WO2018171882A1 PCT/EP2017/056893 EP2017056893W WO2018171882A1 WO 2018171882 A1 WO2018171882 A1 WO 2018171882A1 EP 2017056893 W EP2017056893 W EP 2017056893W WO 2018171882 A1 WO2018171882 A1 WO 2018171882A1
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
gdaxb
blu
core
doped
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2017/056893
Other languages
English (en)
Inventor
Thomas JÜSTEL
Sara ESPINOZA VILLALBA
Matthias Müller
R. Rox Anderson
Martin Purschke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fachhochschule Muenster
General Hospital Corp
Original Assignee
Fachhochschule Muenster
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fachhochschule Muenster, General Hospital Corp filed Critical Fachhochschule Muenster
Priority to PCT/EP2017/056893 priority Critical patent/WO2018171882A1/fr
Publication of WO2018171882A1 publication Critical patent/WO2018171882A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/77742—Silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/7777—Phosphates
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/778—Borates

Definitions

  • Example III refers to (Luo.98Pro.oiGdo.oi) 2 Si05 which was made the following way:

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Luminescent Compositions (AREA)

Abstract

La présente invention concerne des nanoparticules qui sont dopées avec Gd 3+ de manière qu'elles sont capables d'émettre un rayonnement UV, mais qui sont également paramagnétiques et détectables par des techniques RM.
PCT/EP2017/056893 2017-03-22 2017-03-22 Nanoparticules magnétoluminescentes Ceased WO2018171882A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/EP2017/056893 WO2018171882A1 (fr) 2017-03-22 2017-03-22 Nanoparticules magnétoluminescentes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2017/056893 WO2018171882A1 (fr) 2017-03-22 2017-03-22 Nanoparticules magnétoluminescentes

Publications (1)

Publication Number Publication Date
WO2018171882A1 true WO2018171882A1 (fr) 2018-09-27

Family

ID=58410308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/056893 Ceased WO2018171882A1 (fr) 2017-03-22 2017-03-22 Nanoparticules magnétoluminescentes

Country Status (1)

Country Link
WO (1) WO2018171882A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090014685A1 (en) * 2006-03-06 2009-01-15 Koninklijke Philips Electronics N.V. Luminescent material using (y, gd)-containing nanoparticle and surface bound organtic ligands
US20090226724A1 (en) * 2005-11-28 2009-09-10 National Research Council Of Canada Multifunctional nanostructure and method
WO2013001444A1 (fr) * 2011-06-29 2013-01-03 Koninklijke Philips Electronics N.V. Particules d'un matériau luminescent comportant un revêtement et dispositif d'éclairage comprenant ledit matériau luminescent
US20130115172A1 (en) * 2011-11-08 2013-05-09 Korea Institute Of Science And Technology Magnetic nanophosphor having core/shell structure and the synthetic method thereof
US8636921B1 (en) * 2012-10-23 2014-01-28 Industrial Technology Research Institute Phosphate phosphor and UV light-emitting device utilizing the same
CN103623437B (zh) * 2013-12-01 2015-08-19 中国科学院上海硅酸盐研究所 一种成像用纳米探针材料及其制备方法和应用

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090226724A1 (en) * 2005-11-28 2009-09-10 National Research Council Of Canada Multifunctional nanostructure and method
US20090014685A1 (en) * 2006-03-06 2009-01-15 Koninklijke Philips Electronics N.V. Luminescent material using (y, gd)-containing nanoparticle and surface bound organtic ligands
WO2013001444A1 (fr) * 2011-06-29 2013-01-03 Koninklijke Philips Electronics N.V. Particules d'un matériau luminescent comportant un revêtement et dispositif d'éclairage comprenant ledit matériau luminescent
US20130115172A1 (en) * 2011-11-08 2013-05-09 Korea Institute Of Science And Technology Magnetic nanophosphor having core/shell structure and the synthetic method thereof
US8636921B1 (en) * 2012-10-23 2014-01-28 Industrial Technology Research Institute Phosphate phosphor and UV light-emitting device utilizing the same
CN103623437B (zh) * 2013-12-01 2015-08-19 中国科学院上海硅酸盐研究所 一种成像用纳米探针材料及其制备方法和应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MIMUN L CHRISTOPHER ET AL: "Synthesis and characterization of Na(Gd0.5Lu0.5)F4: Nd3+,a core-shell free multifunctional contrast agent", JOURNAL OF ALLOYS AND COMPOUNDS, vol. 695, 2012, pages 280 - 285, XP029856762, ISSN: 0925-8388, DOI: 10.1016/J.JALLCOM.2016.10.202 *
SHAN LU ET AL: "Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 54, no. 27, 26 May 2015 (2015-05-26), pages 7915 - 7919, XP055430878, ISSN: 1433-7851, DOI: 10.1002/anie.201501468 *

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