WO2018157868A1 - Ultrasonic imaging system and imaging method thereof - Google Patents
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- This invention relates to an ultrasound imaging system, and more particularly to an ultrasound imaging system for automatically distinguishing peripheral nerve images and/or anesthetic drugs in real time and a method of imaging the same.
- Peripheral nerve block is a local anesthetic injection around the target nerve to temporarily block the sensory and motor nerve conduction in a specific area, reduce pain during surgery, and strengthen postoperative recovery.
- the Haar feature based cascade classifiers are an effective target detection method proposed by Paul Viola and Michael Jones in 2001 (P. Viola and M. Jones, "Rapid object detection using a boosted cascade of simple features," in Proceedings of the 2001 IEEE Computer Society Conference on Computer Vision and Pattern Recognition. CVPR 2001, 2001, pp. I-511-I-518 vol. 1.).
- the machine learning method proposed by Paul and Michael for target detection can quickly process images and achieve high detection rates.
- Target detection has three key contributions: integral imagery, AdaBoost-based learning calculations, and the ability to combine complex classifiers into a "cascading" approach.
- AdaBoost learning calculation method requires a large number of positive images (only images of target and surrounding tissues) and negative images (with no target images) to train the classifier.
- Fig. 1(a)-Fig.1(c) A schematic diagram of the Hal character shown.
- Each feature is a single value that is calculated by subtracting the pixels under the black rectangle from the sum of the pixels under the white rectangle. Most of the calculated features are irrelevant. Therefore, the variant of AdaBoost is to perform the selection of a small feature set and training classifier (Y.Freund and RESchapire, "A Decision-Theoretic Generalization of On-Line Learning and an Application to Boosting," Journal of Computer and System Sciences , vol. 55, pp. 119-139, 1997/08/01 1997.), in its original form, used to improve the classification performance of weak learning calculations.
- a weak learning calculation method was designed to select a single rectangular feature that can best separate the positive and negative images. For each feature, the weak learner determines the optimal threshold classification function.
- a "cascade" classifier structure is used. The structure of the cascaded classifier not only achieves detection performance but also reduces computation time. The key reason is that it is smaller and more efficient, so the upgraded classifier can reject many negative subwindows (cascades) when positive instances are detected. 2 is a schematic structural view of a cascade classifier.
- the present invention utilizes the Hal feature of level-based learner learning to detect nerves, and can help an anesthesiologist to automatically address a neural region immediately prior to surgery.
- the present invention provides an ultrasonic imaging system, comprising: an ultrasonic probe for acquiring an ultrasonic image including a nerve and surrounding tissue; and an ultrasonic device coupled to the ultrasonic probe for collecting the ultrasonic image; An image capturing device is connected to the ultrasonic device for converting the ultrasonic image; and an arithmetic device is connected to the image capturing device for scanning the ultrasonic image to obtain an ultrasonic scanned image, and the ultrasonic wave A specific feature in the scanned image is indicated by a color; and a developing device is coupled to the computing device for displaying the ultrasonic scanned image in real time and the color for indicating the particular feature.
- the computing device may further mark a plurality of the specific features in the ultrasonic scanned image in a plurality of the colors.
- the developing device can display a plurality of the ultrasonic scanned images in real time, and mark a plurality of the colors of the plurality of the specific features.
- a plurality of said specific features may be nerve regions or local anesthetic regions.
- the ultrasonic source device and the image capturing device further have an image source line.
- the image taking device and the calculating device further have a connecting line.
- the present invention also provides a method for developing an ultrasonic imaging system, which can be used for detecting a nerve region, and is characterized by the following steps: Step 1, based on the characteristics of Haar, analyzing the ultrasonic image, detecting Detect possible neural candidate regions to achieve real-time imaging effects; Step 2, depth-based neural network identification method, complete neural region localization in real time; and step 3, according to image pixel intensity distribution in the neural region, by The image with high pixel value is discolored, the nerve tissue is separated from the background, and the nerve tissue is presented in real time with a color.
- the imaging method can be used for detecting an anesthetic drug region, and the method comprises the following steps: Step 1, based on the Haar feature, analyzing the ultrasound image to detect possible nerve candidate regions, The effect of real-time imaging is achieved; in step 2, the depth-based neural network identification method is used to complete the localization of the neural region in real time; and in step 3, according to the image pixel intensity distribution in the neural region, by changing the image with high pixel value, The nerve tissue is separated from the background, and the nerve tissue is presented in real time in one color; and in step 4, the nerve tissue is mainly used, the detection range is increased, the pixel intensity around the nerve tissue is analyzed, and the range of the anesthetic drug is confirmed, and The range is presented in real time in another color.
- Figure 1 (a) is a schematic diagram of the Haar feature of a rectangular feature (edge feature).
- Fig. 1(b) is a schematic diagram of Haar characteristics of a 3 rectangular feature (line feature).
- Fig. 1(c) is a schematic diagram of the Haar feature of a 4-rectangular feature.
- FIG. 2 is a schematic structural view of a cascade classifier.
- Figure 3 is a schematic diagram of a common ultrasound guided peripheral nerve block system.
- FIG. 4 is a schematic view of an embodiment of an ultrasonic imaging system of the present invention.
- Fig. 5 is a flow chart showing a method of developing a nerve region of the ultrasonic imaging system of the present invention.
- Figure 6 is a schematic view of a detection area in a neuroimaging image.
- Figure 7 is a schematic diagram of the coloration of the nerve region.
- Figure 8 is a schematic diagram of a traceable development mode.
- Fig. 9(a) is a schematic view of an ultrasound image including nerves and surrounding tissues.
- Fig. 9(b) is a schematic view of an ultrasonic image excluding nerves.
- Fig. 10 is a flow chart showing an anesthetic drug region developing method of the ultrasonic imaging system of the present invention.
- Figure 11 is a schematic view showing the coloration of the nerve region and the anesthetic drug region.
- FIG. 3 is a schematic diagram of a conventional ultrasonic guided peripheral nerve blocking system 1 including an ultrasonic probe 11, an ultrasonic device 12, and an ultrasonic image playback device 13.
- the ultrasonic guided peripheral nerve blocking system 1 of FIG. 3 obtains an ultrasonic image including the nerve and the surrounding tissue using the ultrasonic probe 11, and then transmits the ultrasonic image to the ultrasonic image playing device 13 via the ultrasonic device 12, and then the operator
- the ultrasonic image on the ultrasonic image playback device 13 is visually observed, the nerve position in the ultrasonic image is judged, or the nerve stimulator is used to strike the human body, and the nerve is moved to identify the true nerve position to inject the anesthetic.
- the shortcoming of the ultrasound-guided peripheral nerve block system 1 is that it depends on the experience of the operating physician to correctly determine the peripheral nerve position, and cannot perform real-time analysis to assist diagnosis and treatment; in addition, knocking on the human body may also cause other human body Part of the damage.
- the ultrasonic imaging system 2 includes an ultrasonic probe 21, an ultrasonic device 22, an image capturing device 23, a calculating device 24, and a developing device 25.
- the image source line can be DVI, HDMI, or DSUB.
- the image capture device 23 includes, but is not limited to, a capture cartridge.
- computing device 24 includes, but is not limited to, a notebook computer.
- imaging device 25 includes, but is not limited to, a computer screen.
- the ultrasonic imaging system 2 acquires an ultrasonic image including a nerve and a surrounding tissue using the ultrasonic probe 21, and transmits the ultrasonic image to the image capturing device 23 via the ultrasonic device 22 and the image source line 221, and then transmits the image capturing device. 23.
- the ultrasonic image is converted to the calculation device 24 via the connection line 231.
- the calculating device 24 scans the ultrasonic image by using a neural detection algorithm, and then displays the nerve tissue in the ultrasonic scanned image in real time with a significant color, and displays the result on the developing device 25.
- the ultrasonic imaging system 2 provided by the present invention can correctly mark the nerve position in real time, the ultrasonic imaging system 2 provided by the present invention can be used without the nerve stimulation as compared with the ultrasonic guided peripheral nerve blocking system 1 of FIG.
- an auxiliary tool such as a device, it is possible to identify a true nerve position from a soft tissue including a nerve, to put the drug into the correct area, to help an operator with and/or experience, and to more easily identify and evaluate the local anesthetic.
- the injection position avoids the misuse of drugs and has an adverse effect on the human body.
- FIG. 5 is a flow chart of a developing method of the ultrasonic imaging system 2 of the present invention
- FIG. 6 is a schematic view of a detecting area in a neuroimaging image
- FIG. 7 is a schematic view showing a coloring of a nerve region.
- the imaging method of the ultrasonic imaging system 2 provided by the present invention has the following steps:
- Step S241 the first stage of the neural candidate region detecting step, scanning and analyzing the ultrasonic image based on the Haar feature, and detecting a possible neural candidate region (as shown in FIG. 6), in order to achieve real-time imaging effect.
- the area selected in step S241 is not completely correct or unique;
- Step S242 the second stage of the neural region identification step, using the depth-like neural network to complete the positioning of the neural region in real time for the ultrasound scan image;
- Step S243 a step of identifying the nerve tissue in the nerve region, and identifying the nerve tissue according to the image pixel intensity distribution in the neural region, and dissociating the nerve tissue from the background by discoloring the image with high pixel value, and highlighting The color presents the neural tissue in real time.
- step S241 to step S243 is performed by the calculating device 24 of the ultrasonic developing system 2, and the developing result is displayed on the developing device 25 in real time by the developing device 25 (as shown in FIG. 7). Show) to assist the operator in real-time analysis of the correct nerve location.
- FIG. 8 is a schematic diagram of a traceable development mode.
- the imaging method of the ultrasonic imaging system 2 provided by the present invention can continuously mark the nerve tissue scanned in the ultrasonic image on the developing device 25 in real time with different significant colors.
- the neural tissue of the first ultrasonic scanned image is presented in the first color on the developing device 25, and the second ultrasonic scanned image is obtained from the plurality of ultrasonic scanned images confirmed in steps S241 to S243.
- the neural tissue will be presented in a second color on the imaging device 25... and so on, providing the operator with a traceable imaging mode.
- Fig. 9(a) is a schematic view of an ultrasonic image including nerves and surrounding tissues
- Fig. 9(b) is a schematic view of an ultrasonic image not including nerves.
- the present invention utilizes a Hal feature and a cascading learning calculation extracted from training images (including but not limited to the ultrasound images of Figures 9(a) and 9(b) to find regions of the nerve to The development method of steps S241 to S243 is implemented.
- Fig. 10 is a flow chart showing another development method of the ultrasonic imaging system 2 of the present invention
- Fig. 11 is a schematic view showing the coloration of the nerve region and the anesthetic drug region.
- the method of the present invention for finding a nerve region can be used to find an area of anesthetic drug that is applied around a nerve region.
- the imaging method of the ultrasonic imaging system 2 provided by the present invention in some embodiments, has the following steps:
- Step S241 the first stage of the neural candidate region detecting step, scanning and analyzing the ultrasonic image based on the Haar feature, and detecting a possible neural candidate region (as shown in FIG. 6), in order to achieve real-time imaging effect.
- the area selected in step S241 is not completely correct or unique;
- Step S242 the second stage of the neural region identification step, using the depth-like neural network to complete the positioning of the neural region in real time for the ultrasound scan image;
- Step S2431 a step of identifying the nerve tissue in the nerve region, identifying the nerve tissue according to the image pixel intensity distribution in the neural region, and dissociating the nerve tissue from the background by discoloring the image with high pixel value, and highlighting The color presents the neural tissue in real time;
- Step S2432 a step of identifying the anesthetic drug around the nerve tissue, focusing on the nerve tissue, increasing the detection range, analyzing the pixel intensity around the nerve tissue, confirming the range of the anesthetic drug, and presenting the effect in real time in another significant color. range.
- step S241 to step S2432 is performed by the calculating device 24 of the ultrasonic developing system 2, and the developing result is displayed on the developing device 25 in real time by the developing device 25 (as shown in FIG. 11). To assist the operator in confirming the scope of the anesthetic that has been applied to determine whether the anesthetic is completely covered with nerve tissue.
- the identified pixel value of the anesthetic is differentiated by 60 pixels, and if the pixel value is below 60 pixels, it is not rendered in a significant color.
- the imaging device 25 can display not only the original ultrasound image, but also an ultrasound scan image that colors the nerve region and/or the anesthetic drug region for the operator to confirm the original ultrasound image and the colored ultrasound scan. Whether the image positions match each other.
- the present invention assists an unexperienced peripheral nerve block operation by automatically addressing the neural region immediately and marking the position of the nerve region and/or the location of the anesthetic drug region in a significant color by using the Hal feature of the cascade learning calculation method.
- the physician identifies the true nerve position in the soft tissue including the nerve; the invention can determine the correct nerve position without using the nerve stimulator to strike the human body, and avoids the need for the traditional peripheral nerve block surgery to hit the human body with the auxiliary tool The problem of damage to the ligament or soft tissue, etc.; the invention also avoids the adverse effects of the anesthetic drug on the human body, and confirms the scope of the anesthetic drug, thereby determining that the drug can completely cover the nerve tissue, further Improve the success rate and effectiveness of nerve blockade. Therefore, the present invention not only contributes to the technical education of peripheral nerve blockade, but also is beneficial to clinical diagnosis and treatment, solves the existing technical problems, and achieves better effects.
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Abstract
Description
本发明是关于一种超声波显像系统,更具体地说,是关于一种用于实时自动辨别周边神经影像和/或麻醉药物的超声波显像系统及其显像方法。BACKGROUND OF THE
身体神经的分布可分为两大类,分别是中枢神经以及周围神经(Peripheral nerve)。周围神经阻断术(Peripheral nerve block),是在目标神经周围注射局部麻醉剂,以使特定区域的感觉及运动神经传导暂时受阻,减轻手术过程中的疼痛,并强化术后恢复能力。The distribution of body nerves can be divided into two categories, the central nervous system and the peripheral nerve (Peripheral nerve). Peripheral nerve block is a local anesthetic injection around the target nerve to temporarily block the sensory and motor nerve conduction in a specific area, reduce pain during surgery, and strengthen postoperative recovery.
传统的周围神经阻断术,是以盲目的方式注射局部麻醉药,并透过神经刺激器引起的运动反应,来确认神经的位置,因此,施行传统周围神经阻断术,需要使用大量的局部麻醉剂,除了效果不稳定,还伴随着更多不良反应。近年则发展出另一种常见的超声波导引周边神经阻断系统,藉由超声波影像的指引,使神经阻断成功率变得更高、不良反应更少、起效更快、效果相当,且麻醉量最小。一些患者通过有经验的操作者的滑动、倾斜和旋转超声波探头的技术,获得令人满意的周围神经超声波成像。Traditional peripheral nerve blockade is a blind injection of local anesthetics and the movement of the nerve stimulator to confirm the position of the nerve. Therefore, the implementation of traditional peripheral nerve blockade requires the use of a large number of local Anesthetic, in addition to the unstable effect, is accompanied by more adverse reactions. In recent years, another common ultrasound-guided peripheral nerve block system has been developed. With the guidance of ultrasound imaging, the success rate of nerve blockade is higher, the adverse reactions are less, the effect is faster, and the effect is equivalent. The amount of anesthesia is minimal. Some patients obtain satisfactory peripheral ultrasound imaging through the technique of sliding, tilting, and rotating the ultrasound probe of an experienced operator.
然而,对于不具备周围神经阻断术操作经验的新人而言,一些患者的超声波影像中,具有包括神经的类似超声波回声(echogenicity)的软组织,而难以鉴别真正的神经位置,故仍需使用神经刺激器来协助判断,以避免将药物投入错误位置而对人体产生不良作用。因此,为了解决上述缺点,有必要提供一种实时超声波分析系统,来辅助操作医师进行诊断、治疗和教育。However, for newcomers who do not have experience in peripheral nerve blockade surgery, some patients have ultrasound images that include echogenic echogenicity, which is difficult to identify true nerve locations, so nerves still need to be used. The stimulator is used to assist in the judgment to avoid putting the drug into the wrong position and adversely affecting the human body. Therefore, in order to solve the above disadvantages, it is necessary to provide a real-time ultrasonic analysis system to assist the operating physician in diagnosis, treatment and education.
在现有技术中,基于级联分类器的哈尔特征(Haar feature based cascade classifiers),是Paul Viola和Michael Jones在2001年提出的一种有效的目标检测方法(P.Viola and M.Jones,"Rapid object detection using a boosted cascade of simple features,"in Proceedings of the 2001IEEE Computer Society Conference on Computer Vision and Pattern Recognition.CVPR 2001,2001,pp.I-511-I-518 vol.1.)。Paul和Michael提出的用于目标检测的机器学习方法,可以快速处理影像并实现高检测率。目标检测有三个关键的贡献:积分影像、基于AdaBoost的学习计算方式,以及将复杂的分类器组合成一个“级联”的方法。AdaBoost学习计算方式需要大量的正面影像(只有目标和周围组织的影像)和负面影像(没有目标的影像)来训练分类器,从训练影像中,提取如图1(a)-图1(c)所示的哈尔特征示意图。每个特征是一个单一值,是通过白色矩形下的像素总和减去黑色矩形下的像素和计算而得。在所有计算的特征中,大多数是无关紧要的。因此,AdaBoost的变异型是执行选择一个小的特征集和训练分类器(Y.Freund and R.E.Schapire,"A Decision-Theoretic Generalization of On-Line Learning and an Application to Boosting,"Journal of Computer and System Sciences,vol.55,pp.119-139,1997/08/01 1997.),以其原始形式,用来提升弱学习计算方式的分类性能。为了找出少量的特征并形成一个有效的分类器,设计了弱学习计算方式,来选择最能分离正影像和负影像的单个矩形特征。对于每个特征,弱学习者决定了最佳的阈值分类函数。然而,为了提高神经检测的性能,使用了“级联”分类器结构。级联分类器的结构不仅实现了检测性能,而且减少了计算时间。关键的原因是更小和更有效率,因此,升级的分类器可以在检测到正实例(positive instances)时拒绝许多负子窗口(级联器)。图2为级联分类器的结构示意图。In the prior art, the Haar feature based cascade classifiers are an effective target detection method proposed by Paul Viola and Michael Jones in 2001 (P. Viola and M. Jones, "Rapid object detection using a boosted cascade of simple features," in Proceedings of the 2001 IEEE Computer Society Conference on Computer Vision and Pattern Recognition. CVPR 2001, 2001, pp. I-511-I-518 vol. 1.). The machine learning method proposed by Paul and Michael for target detection can quickly process images and achieve high detection rates. Target detection has three key contributions: integral imagery, AdaBoost-based learning calculations, and the ability to combine complex classifiers into a "cascading" approach. AdaBoost learning calculation method requires a large number of positive images (only images of target and surrounding tissues) and negative images (with no target images) to train the classifier. From the training images, extract as shown in Fig. 1(a)-Fig.1(c) A schematic diagram of the Hal character shown. Each feature is a single value that is calculated by subtracting the pixels under the black rectangle from the sum of the pixels under the white rectangle. Most of the calculated features are irrelevant. Therefore, the variant of AdaBoost is to perform the selection of a small feature set and training classifier (Y.Freund and RESchapire, "A Decision-Theoretic Generalization of On-Line Learning and an Application to Boosting," Journal of Computer and System Sciences , vol. 55, pp. 119-139, 1997/08/01 1997.), in its original form, used to improve the classification performance of weak learning calculations. In order to find a small number of features and form an effective classifier, a weak learning calculation method was designed to select a single rectangular feature that can best separate the positive and negative images. For each feature, the weak learner determines the optimal threshold classification function. However, in order to improve the performance of neural detection, a "cascade" classifier structure is used. The structure of the cascaded classifier not only achieves detection performance but also reduces computation time. The key reason is that it is smaller and more efficient, so the upgraded classifier can reject many negative subwindows (cascades) when positive instances are detected. 2 is a schematic structural view of a cascade classifier.
在现有技术中,并没有基于级联机器学习的哈尔特征及检测神经的相关文献或应用。本发明利用基于级联机器学习的哈尔特征来检测神经,能够帮助麻醉师在手术前全自动地立即寻址神经区域。In the prior art, there is no Hal document and learning related literature or application based on the level of online learning. The present invention utilizes the Hal feature of level-based learner learning to detect nerves, and can help an anesthesiologist to automatically address a neural region immediately prior to surgery.
发明内容Summary of the invention
本发明提供一种超声波显像系统,其特征在于包括一超声波探头,用于取得包括神经和周围组织的一超声波影像;一超声波设备,接于所述超声波探头,用于收集所述超声波影像;一取像装置,接于所述超声波设备,用于转换所述超声波影像;一演算装置,接于所述取像装置,用于扫描所述超声波影像,取得一超声波扫描影像,将所述超声波扫描影像中的一特定特征,以一颜色标示;以及一显像装置,接于所述演算装置,用于实时显示所述超声波扫描影像,和用于标示所述特定特征的所述颜色。The present invention provides an ultrasonic imaging system, comprising: an ultrasonic probe for acquiring an ultrasonic image including a nerve and surrounding tissue; and an ultrasonic device coupled to the ultrasonic probe for collecting the ultrasonic image; An image capturing device is connected to the ultrasonic device for converting the ultrasonic image; and an arithmetic device is connected to the image capturing device for scanning the ultrasonic image to obtain an ultrasonic scanned image, and the ultrasonic wave A specific feature in the scanned image is indicated by a color; and a developing device is coupled to the computing device for displaying the ultrasonic scanned image in real time and the color for indicating the particular feature.
根据上述构想,其中演算装置进一步可将所述超声波扫描影像中的多个所述特定特征,以多个所述颜色标示。According to the above concept, the computing device may further mark a plurality of the specific features in the ultrasonic scanned image in a plurality of the colors.
根据上述构想,其中显像装置可实时显示多个所述超声波扫描影像,以及标示多个所述特定特征的多个所述颜色。According to the above concept, the developing device can display a plurality of the ultrasonic scanned images in real time, and mark a plurality of the colors of the plurality of the specific features.
根据上述构想,其中多个所述特定特征可以为神经区域或局部麻醉剂区域。According to the above concept, a plurality of said specific features may be nerve regions or local anesthetic regions.
根据上述构想,其中超声波设备及所述取像装置之间更进一步具有影像源线。According to the above concept, the ultrasonic source device and the image capturing device further have an image source line.
根据上述构想,其中取像装置及所述演算装置之间更进一步具有连接线。According to the above concept, the image taking device and the calculating device further have a connecting line.
另一方面,本发明亦提供一种超声波显像系统的显像方法,可用于侦测神经区域,其特征在于包括以下步骤:步骤1,以哈尔特征为基础,对超声波影像进行分析,侦测出可能的神经候选区域,以达到实时显像的效果;步骤2,由深度类神经网络辨识方法,实时完成神经区域的定位;以及步骤3,依据神经区域内的影像像素强度分布,藉由使像素值高的影像变色,令所述神经组织与背景分离,以一颜色实时呈现所述神经组织。In another aspect, the present invention also provides a method for developing an ultrasonic imaging system, which can be used for detecting a nerve region, and is characterized by the following steps:
根据上述构想,其中显像方法,可用于侦测麻醉药物区域,其特征在于包括以下步骤:步骤1,以哈尔特征为基础,对超声波影像进行分析,侦测出可能的神经候选区域,以达到实时显像的效果;步骤2,由深度类神经网络辨识方法,实时完成神经区域的定位;步骤3,依据神经区域内的影像像素强度分布,藉由使像素值高的影像变色,令所述神经组织与背景分离,以一颜色实时呈现所述神 经组织;以及步骤4,以神经组织为主,加大侦测范围,分析神经组织周围的像素强度,确认麻醉药物施打的范围,并以另一颜色实时呈现该范围。According to the above concept, the imaging method can be used for detecting an anesthetic drug region, and the method comprises the following steps:
图1(a)为2矩形特征(边缘特征)的哈尔特征示意图。Figure 1 (a) is a schematic diagram of the Haar feature of a rectangular feature (edge feature).
图1(b)为3矩形特征(线特征)的哈尔特征示意图。Fig. 1(b) is a schematic diagram of Haar characteristics of a 3 rectangular feature (line feature).
图1(c)为4矩形特征的哈尔特征示意图。Fig. 1(c) is a schematic diagram of the Haar feature of a 4-rectangular feature.
图2为级联分类器的结构示意图。2 is a schematic structural view of a cascade classifier.
图3为一常见的超声波导引周边神经阻断系统示意图。Figure 3 is a schematic diagram of a common ultrasound guided peripheral nerve block system.
图4为本发明的超声波显像系统的一实施例示意图。4 is a schematic view of an embodiment of an ultrasonic imaging system of the present invention.
图5为本发明的超声波显像系统的神经区域显像方法流程图。Fig. 5 is a flow chart showing a method of developing a nerve region of the ultrasonic imaging system of the present invention.
图6为神经影像中的检测区域示意图。Figure 6 is a schematic view of a detection area in a neuroimaging image.
图7为神经区域着色示意图。Figure 7 is a schematic diagram of the coloration of the nerve region.
图8为可追踪式显像模式示意图。Figure 8 is a schematic diagram of a traceable development mode.
图9(a)为包括神经和周围组织的超声波影像示意图。Fig. 9(a) is a schematic view of an ultrasound image including nerves and surrounding tissues.
图9(b)为不包括神经的超声波影像示意图。Fig. 9(b) is a schematic view of an ultrasonic image excluding nerves.
图10为本发明的超声波显像系统的麻醉药物区域显像方法流程图。Fig. 10 is a flow chart showing an anesthetic drug region developing method of the ultrasonic imaging system of the present invention.
图11为神经区域及麻醉药物区域着色示意图。Figure 11 is a schematic view showing the coloration of the nerve region and the anesthetic drug region.
除非另外定义,本文中所使用的所有技术及科学词汇为在此领域具通常知识者所明了的相同意义。Unless otherwise defined, all technical and scientific terms used herein have the same meaning meaning
本发明将可透过以下的实施例说明而让在此领域具通常知识者了解其创作精神,并可据以完成。The present invention will be described by the following examples, so that those skilled in the art can understand the spirit of their creation and can accomplish it.
本发明的实施并非由下列实施例而限制其实施型态。The implementation of the present invention is not limited by the following embodiments.
图3为一常见的超声波导引周边神经阻断系统1示意图,包括超声波探头11、超声波设备12,以及超声波影像播放装置13。3 is a schematic diagram of a conventional ultrasonic guided peripheral
图3的超声波导引周边神经阻断系统1,是使用超声波探头11取得包括神经和周围组织的超声波影像后,将所述超声波影像经由超声波设备12传送至超声波影像播放装置13,再由操作医师以肉眼观察超声波影像播放装置13上的超声波影像,判断所述超声波影像中的神经位置,或者使用神经刺激器敲击人体,使神经产生运动以鉴别真正的神经位置,来注射麻醉药物。因此,超声波导引周边神经阻断系统1的缺点,在于十分仰赖操作医师的经验,才能正确判定周边神经位置,而无法进行实时分析来辅助诊断及治疗;此外,敲击人体也可能造成人体其他部位的损伤。The ultrasonic guided peripheral
图4为本发明的超声波显像系统2的一实施例示意图,超声波显像系统2包括超声波探头21、超声波设备22、取像装置23、演算装置24,以及显像装置25。在超声波设备22及取像装置23之间有影像源线221。在取像装置23及演算装置24之间有连接线231。在一些实施例中,影像源线可以为DVI、HDMI或DSUB。在另一些实施例中,取像装置23包括但不限于取像盒。在一些实施例中,演算装置24包括但不限于笔记本电脑。在另一些实施例中,显像装置25包括但不限于计算机屏幕。4 is a schematic view showing an embodiment of an
本发明提供的超声波显像系统2,是使用超声波探头21取得包括神经和周围组织的超声波影像,将超声波影像经由超声波设备22及影像源线221传送到取像装置23,再透过取像装置23,将超声波影像经由连接线231转换至演算装置24。其中,演算装置24是以神经侦测算法扫描超声波影像,再将超声波扫描影像中的神经组织,以一显著颜色实时标示,并将其结果显示于显像装置25上。The
由于本发明提供的超声波显像系统2可以实时正确标示神经位置,因此,与图3的超声波导引外围神经阻断系统1相比,本发明提供的超声波显像系统2能够在不使用神经刺激器等辅助工具的情况下,即可从具有包括神经的软组织中鉴别真正的神经位置,将药物投入正确区域,帮助具备和/或不具备经验的操作者, 更容易识别及评估局部麻醉药物的注射位置,避免将药物投入误区而对人体产生不良作用。Since the
图5为本发明的超声波显像系统2的一显像方法流程图,图6为神经影像中的检测区域示意图,图7为神经区域着色示意图。5 is a flow chart of a developing method of the
请见图4到图7,本发明提供的超声波显像系统2的显像方法,在一些实施例中,具有以下步骤:Referring to FIG. 4 to FIG. 7, the imaging method of the
步骤S241,第一阶段的神经候选区域侦测步骤,以哈尔特征为基础来扫描及分析超声波影像,侦测出可能的神经候选区域(如图6所示),为了达到实时显像的效果,在步骤S241中所选出的区域并非完全的正确或是唯一;Step S241, the first stage of the neural candidate region detecting step, scanning and analyzing the ultrasonic image based on the Haar feature, and detecting a possible neural candidate region (as shown in FIG. 6), in order to achieve real-time imaging effect. The area selected in step S241 is not completely correct or unique;
步骤S242,第二阶段的神经区域辨识步骤,运用深度类神经网络,针对超声波扫描影像实时完成神经区域的定位;Step S242, the second stage of the neural region identification step, using the depth-like neural network to complete the positioning of the neural region in real time for the ultrasound scan image;
步骤S243,一辨识神经区域内的神经组织步骤,依据神经区域内的影像像素强度分布辨识出神经组织后,藉由使像素值高的影像变色,令该神经组织与背景分离,并以一显著颜色实时呈现该神经组织。Step S243, a step of identifying the nerve tissue in the nerve region, and identifying the nerve tissue according to the image pixel intensity distribution in the neural region, and dissociating the nerve tissue from the background by discoloring the image with high pixel value, and highlighting The color presents the neural tissue in real time.
步骤S241至步骤S243的显像方法,是透过超声波显像系统2的演算装置24所进行,再藉由显像装置25将上述显像结果实时显示于显像装置25上(如图7所示),以协助操作者针对正确的神经位置进行实时分析。The developing method of step S241 to step S243 is performed by the calculating
图8为可追踪式显像模式示意图。如图8所示,本发明提供的超声波显像系统2的显像方法还可以连续将超声波影像中扫描到的神经组织,以不同的显著颜色实时标示于显像装置25上。在一些实施例中,经由步骤S241至步骤S243所确认的多张超声波扫描影像中,第一张超声波扫描影像的神经组织会在显像装置25上以第一颜色呈现,第二张超声波扫描影像的神经组织会在显像装置25上以第二颜色呈现…以此类推,提供操作医师一个可追踪式显像模式。Figure 8 is a schematic diagram of a traceable development mode. As shown in FIG. 8, the imaging method of the
图9(a)为包括神经和周围组织的超声波影像示意图,图9(b)为不包括神经的超声波影像示意图。在一些实施例中,本发明利用从训练影像(包括但不限于图 9(a)和图9(b)的超声波影像)提取的哈尔特征和级联学习计算方式找出神经的区域,以实现步骤S241至步骤S243的显像方法。Fig. 9(a) is a schematic view of an ultrasonic image including nerves and surrounding tissues, and Fig. 9(b) is a schematic view of an ultrasonic image not including nerves. In some embodiments, the present invention utilizes a Hal feature and a cascading learning calculation extracted from training images (including but not limited to the ultrasound images of Figures 9(a) and 9(b) to find regions of the nerve to The development method of steps S241 to S243 is implemented.
图10为本发明的超声波显像系统2的另一显像方法流程图,图11为神经区域及麻醉药物区域着色示意图。Fig. 10 is a flow chart showing another development method of the
本发明用于找出神经区域的方法,可以用来找出施打于神经区域周围的麻醉药物区域。请见图10及图11,本发明提供的超声波显像系统2的显像方法,在一些实施例中,还具有以下步骤:The method of the present invention for finding a nerve region can be used to find an area of anesthetic drug that is applied around a nerve region. 10 and FIG. 11, the imaging method of the
步骤S241,第一阶段的神经候选区域侦测步骤,以哈尔特征为基础来扫描及分析超声波影像,侦测出可能的神经候选区域(如图6所示),为了达到实时显像的效果,在步骤S241中所选出的区域并非完全的正确或是唯一;Step S241, the first stage of the neural candidate region detecting step, scanning and analyzing the ultrasonic image based on the Haar feature, and detecting a possible neural candidate region (as shown in FIG. 6), in order to achieve real-time imaging effect. The area selected in step S241 is not completely correct or unique;
步骤S242,第二阶段的神经区域辨识步骤,运用深度类神经网络,针对超声波扫描影像实时完成神经区域的定位;Step S242, the second stage of the neural region identification step, using the depth-like neural network to complete the positioning of the neural region in real time for the ultrasound scan image;
步骤S2431,一辨识神经区域内的神经组织步骤,依据神经区域内的影像像素强度分布辨识出神经组织后,藉由使像素值高的影像变色,令该神经组织与背景分离,并以一显著颜色实时呈现该神经组织;Step S2431: a step of identifying the nerve tissue in the nerve region, identifying the nerve tissue according to the image pixel intensity distribution in the neural region, and dissociating the nerve tissue from the background by discoloring the image with high pixel value, and highlighting The color presents the neural tissue in real time;
步骤S2432,一辨识神经组织周围的麻醉药物步骤,以神经组织为主,加大侦测范围,分析神经组织周围的像素强度,确认麻醉药物施打的范围,并以另一显著颜色实时呈现该范围。Step S2432, a step of identifying the anesthetic drug around the nerve tissue, focusing on the nerve tissue, increasing the detection range, analyzing the pixel intensity around the nerve tissue, confirming the range of the anesthetic drug, and presenting the effect in real time in another significant color. range.
步骤S241至步骤S2432的显像方法,是透过超声波显像系统2的演算装置24所进行,再藉由显像装置25将上述显像结果实时显示于显像装置25上(如图11所示),以协助操作医师确认已施打麻醉药物的范围,确定麻醉药物是否完整包覆神经组织。The developing method of step S241 to step S2432 is performed by the calculating
在一实施例中,麻醉药物的辨识像素值是以60pixel作为区别,如像素值为60pixel以下则不以显著颜色呈现。In one embodiment, the identified pixel value of the anesthetic is differentiated by 60 pixels, and if the pixel value is below 60 pixels, it is not rendered in a significant color.
在一些实施例中,显像装置25不仅可以显示原始超声波影像,还可以同时显示将神经区域和/或麻醉药物区域进行着色的超声波扫描影像,以供操作医师确认原始超声波影像及着色的超声波扫描影像位置是否互相吻合。In some embodiments, the
本发明藉由基于级联学习计算方式的哈尔特征,自动立即寻址神经区域并以显著颜色标示出神经区域位置和/或麻醉药物区域位置,可以协助不具备经验的周围神经阻断术操作医师,在具有包括神经的软组织中鉴别真正的神经位置;本发明不需要使用神经刺激器敲击人体,即可判别正确的神经位置,避免了传统周围神经阻断术需要以辅助工具敲击人体,而导致韧带或软组织等部位损伤的问题;本发明还避免将麻醉药物投入误区而对人体产生不良作用,并得以确认已施打麻醉药物的范围,进而确定药物得以完整包覆神经组织,进一步提升神经阻断术的成功率及成效。因此,本发明除了有助于周围神经阻断术的操作技术教育,更有益于临床上的诊断及治疗,解决了现有的技术问题,达到更好的效果。The present invention assists an unexperienced peripheral nerve block operation by automatically addressing the neural region immediately and marking the position of the nerve region and/or the location of the anesthetic drug region in a significant color by using the Hal feature of the cascade learning calculation method. The physician identifies the true nerve position in the soft tissue including the nerve; the invention can determine the correct nerve position without using the nerve stimulator to strike the human body, and avoids the need for the traditional peripheral nerve block surgery to hit the human body with the auxiliary tool The problem of damage to the ligament or soft tissue, etc.; the invention also avoids the adverse effects of the anesthetic drug on the human body, and confirms the scope of the anesthetic drug, thereby determining that the drug can completely cover the nerve tissue, further Improve the success rate and effectiveness of nerve blockade. Therefore, the present invention not only contributes to the technical education of peripheral nerve blockade, but also is beneficial to clinical diagnosis and treatment, solves the existing technical problems, and achieves better effects.
符号说明Symbol Description
S241、S242、S243、S2431、S2432步骤Steps S241, S242, S243, S2431, and S2432
1 导管装置1 catheter device
1 超声波导引周边神经阻断系统1 Ultrasound guided peripheral nerve block system
11 超声波探头11 ultrasonic probe
12 超声波设备12 Ultrasonic equipment
13 超声波影像播放装置13 Ultrasonic video playback device
2 超声波显像系统2 Ultrasonic imaging system
21 超声波探头21 ultrasonic probe
22 超声波设备22 Ultrasonic equipment
23 取像装置23 image capture device
24 演算装置24 calculation device
25 显像装置25 imaging device
221 影像源线221 image source line
231 连接线231 cable
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