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WO2018036294A1 - 一种农药组合物 - Google Patents

一种农药组合物 Download PDF

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Publication number
WO2018036294A1
WO2018036294A1 PCT/CN2017/092640 CN2017092640W WO2018036294A1 WO 2018036294 A1 WO2018036294 A1 WO 2018036294A1 CN 2017092640 W CN2017092640 W CN 2017092640W WO 2018036294 A1 WO2018036294 A1 WO 2018036294A1
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Prior art keywords
composition
thiabendazole
azoxystrobin
active component
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2017/092640
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English (en)
French (fr)
Inventor
仲汉根
季自华
季红进
季定根
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Jiangsu Huifeng Agrochemical Co Ltd
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Jiangsu Huifeng Agrochemical Co Ltd
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Publication of WO2018036294A1 publication Critical patent/WO2018036294A1/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof

Definitions

  • the invention is mainly applied to the field of agricultural plant protection, and is a composition of a plant growth regulator and a bactericide, comprising an active ingredient thifenone and a methoxy acrylate pesticide.
  • Pyraclostrobin is a new type of high-efficiency plant growth regulator. When thidiazepine is absorbed by plants, it can promote the separation of the petioles and stems, thus promoting the shedding of mature leaves. At higher concentrations, it can stimulate the formation of ethylene. Promotes the activity of pectin and cellulase. Under low concentration conditions, it has an cytokines effect and can induce plant callus differentiation and bud emergence.
  • the structure is as follows:
  • the methoxy acrylate fungicide belongs to Qols (Qonespirationinhibi.tons) and is a biomimetic synthetic analogue of natural fungal metabolites. It is a kind of low toxicity, high activity, broad spectrum, systemic fungicide with protection. The role of treatment, eradication. They have good activity against Ascomycetes, Basidiomycetes, Deuteromycetes and Oomycetes, and can control diseases such as powdery mildew, rust, downy mildew and rice blast of various crops.
  • This kind of compound mainly inhibits the mitochondrial respiration by inhibiting the electron transfer between the cytochrome b and c1 of the pathogenic fungus, interferes with the energy supply of the cell, and exerts a bactericidal action, and can be sprayed on the leaf surface or seeded.
  • Azoxystrobin is a highly effective, broad-spectrum fungicide for almost all fungal communities (Ascomycota, Basidiomycotina, Flagellate, and Deuteromyces) diseases such as powdery mildew, rust, and sclerotium. Net spot disease, downy mildew, rice blast, etc. have good activity. It can be used for stem and leaf spray, seed treatment, and soil treatment. It is mainly used for cereals, rice, peanuts, grapes, potatoes, fruit trees, vegetables, coffee, lawns, etc.
  • the azoxystrobin structure is as follows:
  • Pyridoxal is a systemic fungicide with a broad spectrum of control targets, mainly used to control foliar diseases such as leaf blight of wheat. Leaf rust, wing blight, brown spot, powdery mildew, etc. Pyridoxine is a mitochondrial respiratory inhibitor that inhibits mitochondrial respiration by electron transfer between cytochrome b and C1. It is effective to control strains which are resistant to 14-demethylase inhibitors, benzamides, tricarboxamides and benzimidazoles.
  • the picoxystrobin moves in the xylem and flows with the water flow in the transport system; it also flows in the gas phase of the surface of the blade and flows into the xylem as it is absorbed into the blade from the gas phase.
  • the crops treated with oxystrobin [250g(ai)/hm2] under no rain conditions and the crops treated for 2 hours after the same spray treatment were exposed to rainfall of 10 mm for up to 1 h, and the results showed that the two were on barley leaves.
  • the control effect of blight is consistent. It is because of the systemic activity and fumigation activity of picoxystrobin that the active ingredient can be effectively redistributed and fully delivered after application. Therefore, oxystrobin is better than commercial azoxystrobin and trifloxystrobin.
  • Therapeutic activity Suitable for crops and safe wheat such as wheat, barley, oats and rye; safe and non-toxic to crops at the recommended dosage.
  • picoxystrobin The structure of picoxystrobin is:
  • Pyraclostrobin is a new broad-spectrum fungicide.
  • the mechanism of action is mitochondrial respiratory inhibitors, which are protective, therapeutic, and leaf osmotic conduction effects by preventing electron transfer in cytochrome synthesis.
  • the results of field efficacy test of pyraclostrobin emulsion showed good control effect on cucumber powdery mildew, downy mildew and banana scab, leaf spot and sclerotinia.
  • the structural formula of pyraclostrobin is:
  • the object of the present invention is to provide a pesticide composition capable of regulating crop growth and preventing crop diseases, promoting crop growth, controlling crop diseases, rapidly controlling the spread of crop diseases, increasing crop yield, and achieving disease resistance and yield increase. It has been found through experiments that thifibrone and methoxy acrylate fungicides have significant effects in regulating crop growth, controlling crop diseases and increasing single-sided machine yield.
  • Another object of the present invention is to provide a preparation method comprising a combination of two active ingredients A and B agricultural compounds and an application for regulating and promoting crop growth in the agricultural field.
  • the object of the invention can be achieved by the following measures:
  • the invention relates to a pesticide composition, in particular to a synergistic plant growth regulator and a bactericide composition, the composition comprising two active components A and B, wherein the active component A is thiabenzene Long, the active component B is one of the methoxy acrylate fungicides azoxystrobin, picoxystrobin or pyraclostrobin, and the weight ratio between the two components is the active component A and the active group.
  • the weight ratio of the sub-B is 1: (240 to 5).
  • the weight ratio of active ingredient A to active ingredient B is 1: (204 to 10) or 1: (204 to 10).
  • the weight ratio of azoxystrobin and azoxystrobin is 1:204-10
  • the weight ratio of azoxystrobin to picoxystrobin is 1:204-10
  • azoxystrobin and pyraclostrobin The weight ratio of the ester is 1:204 to 10.
  • the weight ratio between the two components of A and B can be arbitrarily adjusted within the range of the following ratios: 1:5, 1:6, 1:7, 1:8, 1:9 , 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:21, 1 :22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30, 1:32, 1:33, 1:34, 1:35 1, 1:36, 1:37, 1:38, 1:39, 1:40, 1:41, 1:42, 1:43, 1:44, 1:45, 1:46, 1:47, 1 : 48, 1:49, 1:50, 1:51, 1:52, 1:53, 1:54, 1:55, 1:56, 1:57, 1:58, 159:, 1:60, 1:61, 1:62, 1:63, 1:64, 1:65, 1:66, 1:67, 1:68, 1
  • the invention finds through experiments that the composition is used for better control of crop diseases.
  • the treatment with the compound can better control the spread of the disease and promote the health effect of the crop. Enhance the disease resistance of crops and improve the quality of crop products.
  • the present invention provides a combination comprising component A (thiabendazole) and component B (methoxy acrylate fungicide selected from the group consisting of azoxystrobin, picoxystrobin or pyraclostrobin)
  • component A thiabendazole
  • component B methoxy acrylate fungicide selected from the group consisting of azoxystrobin, picoxystrobin or pyraclostrobin
  • composition of the present invention can also be used in combination with other pesticides (such as fungicides, insecticides, herbicides, plant growth regulators), fertilizers, etc., and these are mixed with existing ones.
  • pesticides such as fungicides, insecticides, herbicides, plant growth regulators
  • fertilizers etc.
  • composition of the present invention can be made into a pesticide-acceptable dosage form from the active ingredient and the pesticide adjuvant.
  • the active ingredient in the composition has a mass content of from 5 to 85%, preferably from 5 to 60%.
  • composition may specifically comprise an agrochemical auxiliary, such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant, etc., during the application process.
  • an agrochemical auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant, etc.
  • an agrochemical auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant, etc.
  • Suitable auxiliaries may be solid or liquid, they are usually materials commonly used in the processing of dosage forms, such as natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickeners, binders or fertilizers. .
  • the method of application of the compositions of the invention comprises the use of the compositions of the invention for aerial parts of plants, in particular leaves or foliage. You can choose to soak or apply to the surface of the control object.
  • the frequency of administration and the amount administered will depend on the biological and climatic conditions of the pathogen.
  • the plant growth site such as rice fields, may be wetted with a liquid formulation of the composition, or the composition may be applied to the soil in solid form, such as in the form of granules (soil application), the composition may be passed from the soil to the plant through the roots of the plant. In vivo (systemic action).
  • compositions may be applied only with the active ingredient or may be mixed with an additive (agrochemical adjuvant).
  • compositions of the present invention may be prepared in a pesticide acceptable dosage form such as a liquid, suspension, soluble liquid, oil suspension, microcapsule, microemulsion, suspension, and the like.
  • a pesticide acceptable dosage form such as a liquid, suspension, soluble liquid, oil suspension, microcapsule, microemulsion, suspension, and the like.
  • the compositions may be applied by spraying, misting, dusting, spreading or pouring, and the like.
  • Microcapsule dosage forms suitable for the present invention include: microcapsule suspension, microcapsule suspension-suspension, microcapsule suspension-water emulsion, etc., characterized in that the inner wall of the capsule (ie, the capsule core) contains the active ingredient thiabendone and methoxy
  • the acrylate bactericide is mixed into a microcapsule in a mixture of a certain ratio.
  • the microcapsules are stably dispersed and suspended in a certain concentration to form a microcapsule suspending agent in water as a continuous phase.
  • one of the active ingredients is prepared as a microcapsule suspension, another active ingredient is prepared into an emulsion, and the prepared two components are mixed, stirred, and shaken to obtain a microcapsule suspension-suspension or microcapsule suspension.
  • Agent-water emulsion is a microcapsule suspension.
  • composition of the present invention can be prepared into various dosage forms by a known method, and the active ingredient and the auxiliary agent, such as a solvent, a solid carrier, and, if necessary, can be uniformly mixed and ground together with the surfactant to prepare a desired preparation. Dosage form.
  • the above solvent may be selected from aromatic hydrocarbons, preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • aromatic hydrocarbons preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • Alkenes or paraffins, alcohols and glycols and their ethers and esters such as ethanol, ethylene glycol, ethylene glycol monomethyl
  • ketones such as cyclohexanone
  • highly polar solvents such as N-methyl-2 Pyrrolidone, dimethyl sulfoxide or dimethylformamide
  • vegetable or vegetable oils such as soybean oil.
  • the above solid carriers are usually natural mineral fillers such as talc, kaolin, montmorillonite or activated clay.
  • a highly dispersible silicic acid or a highly dispersible adsorbent polymer carrier such as a particulate adsorbent carrier or a non-adsorbing carrier, and a suitable particulate adsorbent carrier is porous.
  • a suitable particulate adsorbent carrier is porous.
  • suitable non-adsorbing carriers such as calcite or sand.
  • a large amount of pre-granulated materials of inorganic or organic nature can be used as a carrier, in particular dolomite.
  • Suitable surfactants are lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkaline earth metal or amine salts, alkylarylsulfonates, alkyl groups Sulfates, alkyl sulfonates, fatty alcohol sulphates, fatty acids and sulfated fatty alcohol glycol ethers, as well as condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, naphthalene or naphthalene sulfonic acid with phenol and formaldehyde Condensate, polyoxyethylene octyl phenyl ether, ethoxylated isooctyl phenol, octyl phenol, nonyl phenol, alkyl aryl polyglycol ether, tributyl benzene poly
  • composition of the present invention can be applied in the agricultural field to regulate crop growth and control crop diseases.
  • Plants in the present invention include, but are not limited to, crops such as rice, cucumber or banana.
  • the two active ingredients in the composition of the present invention exhibit mutual promotion, the activity of the composition is higher than the expected activity of using a single compound, and the planting agent in the present invention can promote plant growth regulation, and the fungicide component can effectively kill Disease killer.
  • the treatment of the crop with the composition can effectively prevent the spread and spread of the pathogen, and can better and better control the crop disease and reduce the impact of the medicine on the crop.
  • the other characteristics exhibited by the composition of the present invention are mainly as follows: 1.
  • the composition of the present invention has a synergistic additive effect and can promote each other; 2 due to the difference in chemical composition of the two single agents of the composition Large, the mechanism of action is completely different, there is no cross-resistance, the crop is safe, and the disease-preventing effect can be greatly improved; 3 the composition reduces the adverse effects caused by the application of the drug to the crop; 4 the composition can be improved Crop yield, quality improvement, and high economic value.
  • the active ingredient and the auxiliary agent are mixed according to a certain ratio, and then finely ground to prepare a thiabendazole azoxystrobin suspension agent, a thiabendazole pyridoxal ester suspension agent, and a thiabendazole pyriazole Ester suspension.
  • Example 1 48% thiabendazole azoxystrobin suspension
  • Example 2 19% thiabendazole azoxystrobin suspension
  • Example 8 19% thiabendazole pyraclostrobin suspension
  • the active ingredients thiablon and azoxystrobin, oxypoxystrobin and pyraclostrobin are mixed in proportion with solvent, emulsifier and flow, and after fine sanding and high-speed shearing, semi-finished products are obtained. Processed into finished products.
  • Example 10 41% thiabendazole azoxystrobin water emulsion
  • Example 11 16% thiabendazole azoxystrobin water emulsion
  • Example 12 15% thiabendazole azoxystrobin water emulsion
  • Example 14 16% thiabendazole ⁇ hyperoxylate aqueous emulsion
  • the effective component thiablon and one of a mixture of azoxystrobin, oxypide and pyraclostrobin are mixed with various auxiliaries and fillers in proportion, and pulverized by an ultrafine pulverizer. Wettable powder.
  • Example 19 35% thiabendazole azoxystrobin wettable powder
  • Example 20 29% thiabendazole azoxystrobin wettable powder
  • Example 22 35% thiabendazole ⁇ picoxybacteride wettable powder
  • Example 23 29% thiabendazole ⁇ picoxystrobin wettable powder
  • Example 24 18% thiabendazole picoxystrobin wettable powder
  • Example 25 35% thiabendazole picoxystrobin wettable powder
  • Example 26 29% thiabendazole pyraclostrobin wettable powder
  • Example 27 18% thiabendazole pyraclostrobin wettable powder
  • Thiabendron 3% Thiabendron 3%, pyraclostrobin 15%, sodium lignin sulfonate 3%, alkyl sulfonate 5%, white carbon black 10%, kaolin to 100%.
  • Example 28 11% thiabendazole azoxystrobin soluble solution
  • Example 30 11% thiabendazole pyraclostrobin soluble liquid agent
  • the thiazole and methoxy acrylate fungicides were diluted with acetone at a certain concentration, and the crops were sprayed to determine the effects of various concentrations on crop growth in the field, including plant height, sheath blight control rate, and rice. Comprehensive evaluation of the prevention and treatment rate of rickets.
  • Plant height increase rate (clear water control plant height - treated plant height) / clear water control plant height * 100%
  • Thousand-grain weight increase rate (1000-grain weight of treated - 1000-grain weight of clear water control) / 1000-grain weight of clear water control *100%
  • Mu yield increase rate (mu yield after treatment - yield per mu of clear water control) / mu yield of clear water control * 100%
  • Table 1 Summary of thiabendazole and methoxy acrylate fungicides in rice growth regulation and disease prevention
  • the inventors found that there is a good synergistic effect between thiabendone and methoxy acrylate fungicide.
  • the thidiazepine and methoxy acrylate fungicide are mixed at different ratios, and the thiobenzene is relatively Long, methoxy acrylate fungicide single agent, and clear water control, the rice growth regulation effect is obvious, mainly in: control rice plant height, increase rice 1000-grain weight, increase rice yield per mu; spray the composition of the invention The incidence rate is greatly reduced, and the disease prevention effect is improved.
  • the thiazole and methoxy acrylate fungicides were diluted with acetone at a certain concentration, and the crops were sprayed to determine the effects of various concentrations on the growth of the crops, including the stem diameter, downy mildew and powdery mildew of the crops. Comprehensive evaluation of the rate and production situation.
  • Stem thickening rate (clear water stem diameter - treated stem diameter) / clear water control stem thick * 100%
  • Rate of fruit growth per plant (single plant fruit of the treated plant - fruit water control group) / fruit setting rate of clear water control * 100%
  • Moisture content increase rate (water content after treatment - moisture content of clean water control) / moisture content of clear water control * 100%
  • the experimental data from Table 2 shows that the product of the present invention is applied in the early stage of cucumber downy mildew and powdery mildew, and can effectively reduce the disease index and improve the control effect when cucumber downy mildew and powdery mildew occur; Thickening; increase the fruit setting rate of cucumber per plant, increase the moisture content of cucumber, and improve the quality of cucumber.

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

本发明公开了一种农药组合物，特别是一种具有增效作用的植物生长调节剂与杀菌剂的组合物，该组合物包含A和B两种活性组分，其中活性组分A为噻苯隆，活性组分B为甲氧基丙烯酸酯类杀菌剂嘧菌酯、啶氧菌酯或吡唑醚菌酯中的一种，两组分之间的重量比为活性组分A和活性组分B的重量比为1：240～5。本农药组合物能够促进作物生长，防治作物病害发生，可快速控制作物病害蔓延，提高作物产量，达到抗病增产的目的。通过试验发现，噻苯隆与甲氧基丙烯酸酯类杀菌剂两者复配后在调节作物生长和防治作物病害，提高单面机产量方面有显著的效果。

Description

一种农药组合物 技术领域
本发明主要应用于农业植保领域，为植物生长调节剂和杀菌剂的组合物，包含活性成分噻苯隆和甲氧基丙烯酸酯类农药。
背景技术
噻苯隆(pyraclostrobin)是新型高效植物生长调节剂，噻苯隆被植物吸收后，可促进叶柄与茎之间的分离组织，从而促进成熟叶片脱落，较高的浓度下可刺激乙烯的生成，促进果胶和纤维素酶的活性。低浓度的条件下，具有细胞动素作用，能诱导植物的愈伤组织分化出芽出来。结构式如下：
Figure PCTCN2017092640-appb-000001
甲氧基丙烯酸酯类杀菌剂属于Qols(Qonespirationinhibi.tons)类药剂，是天然真菌代谢产物的仿生合成类似物，是一类低毒、高活性、广谱性、内吸性杀菌剂，具有保护、治疗、铲除的作用。它们对子囊菌纲、担子菌纲、半知菌纲和卵菌纲等均有良好的活性，能防治多种作物的白粉病、锈病、霜霉病和稻瘟病等病害。该类化合物主要通过抑制病原真菌细胞色素b和c1间的电子传递，以抑制线粒体的呼吸，干扰细胞能量供给，发挥杀菌作用，可以叶面喷雾，也可以进行种子处理。
嘧菌酯为高效、广谱杀菌剂，对几乎所有的真菌界(子囊菌亚门、担子菌亚门、鞭毛菌亚门和半知菌亚门)病害如白粉病、锈病、颖枯病、网斑病、霜霉病、稻瘟病等均有良好的活性。可用于茎叶喷雾、种子处理，也可进行土壤处理，主要用于谷物、水稻、花生、葡萄、马铃薯、果树、蔬菜、咖啡、草坪等。嘧菌酯结构式如下：
Figure PCTCN2017092640-appb-000002
啶氧菌酯是内吸性杀菌剂，防治对象广谱，主要用于防治麦类的叶面病害如叶枯病、 叶锈病、颖枯病、褐斑病、白粉病等。啶氧菌酯为线粒体呼吸抑制剂，即通过在细胞色素b和C1间电子转移抑制线粒体的呼吸。防治对14-脱甲基化酶抑制剂、苯甲酰胺类、三羧酰胺类和苯并咪唑类产生抗性的菌株有效。啶氧菌酯一旦被叶片吸收，就会在木质部中移动，随水流在运输系统中流动；它也在叶片表面的气相中流动并随着从气相中吸收进入叶片后又在木质部中流动。无雨条件下用啶氧菌酯[250g(a.i.)/hm2]喷雾处理的作物和将同样喷雾处理后2h的作物暴露于降雨量为lOmm、长达lh进行比较，结果表明两者对大麦叶枯病的防治效果是一致的。正是由于啶氧菌酯的内吸活性和熏蒸活性，因而施药后，有效成分能有效再分配及充分传递，因此啶氧菌酯比商品化的嘧菌酯和肟菌酯有更好的治疗活性。适宜作物与安全性麦类如小麦、大麦、燕麦及黑麦；摧荐剂量下对作物安全、无药害。
啶氧菌酯结构式为：
Figure PCTCN2017092640-appb-000003
吡唑醚菌酯为新型广谱杀菌剂。作用机理为线粒体呼吸抑制剂，即通过在细胞色素合成中阻止电子转移，具有保护、治疗、叶片渗透传导作用。吡唑醚菌酯乳油经田间药效试验结果表明对黄瓜白粉病、霜霉病和香蕉黑星病、叶斑病、菌核病等有较好的防治效果。吡唑醚菌酯结构式为：
Figure PCTCN2017092640-appb-000004
发明内容
本发明的目的是提供一种既可以调节作物生长又能防止作物病害的农药组合物，促进作物生长，防治作物病害发生，可快速控制作物病害蔓延，提高作物产量，达到抗病增产的目的。通过试验发现，噻苯隆与甲氧基丙烯酸酯类杀菌剂两者复配后在调节作物生长和防治作物病害，提高单面机产量方面有显著的效果。
本发明的另一个目的是提供包含两种有效成分A和B农用化合物组合的制备方法及在农业领域调节和促进农作物生长的应用。
本发明的目的可以通过以下措施达到：
本发明为一种农药组合物，特别是一种具有增效作用的植物生长调节剂与杀菌剂的组合物，该组合物包含A和B两种活性组分，其中活性组分A为噻苯隆，活性组分B为甲氧基丙烯酸酯类杀菌剂嘧菌酯、啶氧菌酯或吡唑醚菌酯中的一种，两组分之间的重量比为活性组分A和活性组分B的重量比为1：(240～5)。
在一种优选方案中，活性组分A和活性组分B的重量比为1：(204～10)或1：(204～10)。在一种优选方案中，嘧菌酯和嘧菌酯的重量比为1：204～10，嘧菌酯和啶氧菌酯的重量比为1：204～10，嘧菌酯和吡唑醚菌酯的重量比为1：204～10。
一种优选的方案中，A和B两组分之间的重量比可以任意地在下述配比的范围内进行调整：1：5、1：6、1：7、1：8、1：9、1：10、1：11、1：12、1：13、1：14、1：15、1：16、1：17、1：18、1：19、1：20、1：21、1：22、1：23、1：24、1：25、1：26、1：27、1：28、1：29、1：30，1:32、1:33、1:34、1:35、1:36、1:37、1:38、1:39、1:40、1:41、1:42、1:43、1:44、1:45、1:46、1:47、1:48、1:49、1:50、1:51、1:52、1:53、1:54、1:55、1:56、1:57、1:58、159:、1:60、1:61、1:62、1:63、1:64、1:65、1:66、1:67、1:68、1:69、1:70、1:71、1:72、1:73、1:74、1:75、1:76、1:77、1:78、1:79、1:80、1:81、1:82、1:83、1:84、1:85、1:86、1:87、1:88、1:89、1:90、1:91、1:92、1:93、1:94、1:95、1:96、1:97、1:98、1:99、1:100、1:110、1:120、1:130、1:140、1:150、1:160、1:170、1:180、1:190、1:200、1:204、1:205、1:210、1:220、1:230、1:240,也可以在以上任意两个配比所组成的范围内进行选择这些比例可以理解为重量比，也可以包括摩尔比。
本发明通过试验发现，该组合物是用于可以更好的防治作物病害，当作物收到病菌侵染时，用该化合物处理可更好更快速地控制病害传播，可促进作物的健康作用，增强作物的抗病能力和提升作物的产品的质量品质。
本发明提供了包含组分A(噻苯隆)和组分B(甲氧基丙烯酸酯类杀菌剂,选自嘧菌酯、啶氧菌酯或吡唑醚菌酯其中的一种)的组合物在农业领域调节农作物生长的用途，特别是在水稻、黄瓜或香蕉方面防治病害、提高抗病性、调节作物生长、增加产量、提高品质等方面的用途。
为充分发挥本发明的作用效果，本发明组合物还可以与其他农药(如杀菌剂、杀虫剂、除草剂、植物生长调节剂)、肥料等混合使用，这些与之混用的均为现有技术公开的常用的农药或肥料。
本发明的组合物可以由活性成分和农药助剂制成农药上允许的剂型。
在一种优选方案中，该组合物中的活性成分的质量含量为5-85％，优选5-60％。
上述组合物具体可包含农药助剂，例如载体、溶剂、分散剂、润湿剂、胶粘剂、增稠剂、粘合剂、表面活性剂等中的一种或几种，在施用的过程中可以混合常用的助剂。
合适的助剂可以是固体或液体，它们通常是剂型加工过程中常用的物质，例如天然的或再生的矿物质，溶剂、分散剂、润湿剂、胶粘剂、增稠剂、粘合剂或肥料。
本发明组合物的施用方法包括将本发明的组合物用于植物生长的地上部分，特别是叶部或叶面。可以选择浸种或涂抹于防治对象表面。施用的频率和施用量取决于病原体的生物学和气候生存条件。可以将植物的生长场所，如稻田，用组合物的液体制剂浸湿，或者将组合物以固体形式施用于土壤中，如以颗粒形式(土壤施用)，组合物可以由土壤经植物根部进入植物体内(内吸作用)。
这些组合物可以仅仅包含活性成分进行施用，也可以与添加剂(农药助剂)一起混合使用。
本发明的组合物可以制备成农药上可接受的剂型，例如水剂、悬浮剂、可溶性液剂、油悬浮剂、微囊剂型、微乳剂、悬浮剂等。根据这些组合物的性质以及施用组合物所要达到的目的和环境情况，可以选择将组合物以喷雾、弥雾、喷粉、撒播或泼浇等之类的方法施用。
适合本发明的微囊剂型包括：微囊悬浮剂、微囊悬浮-悬浮剂、微囊悬浮-水乳剂等，其特征在于囊壁内(即囊芯)包含由有效成分噻苯隆和甲氧基丙烯酸酯类杀菌剂按照一定比例的混合物，即将两者混合制成微型胶囊。将微型胶囊以一定的浓度稳定地分散、悬浮在作为连续相的水中形成微囊悬浮剂。或者将其中一种有效成分制备成微囊悬浮剂，将另外一种有效成分制备成乳液，将制备的两种成分在混合，搅拌，摇匀即得微囊悬浮剂-悬浮剂或微囊悬浮剂-水乳剂。
可用已知的方法可以将本发明的组合物制备成各种剂型，可以将有效成分与助剂，如溶剂、固体载体，需要时可以与表面活性剂一起均匀混合、研磨，制备成所需要的剂型。
上述的溶剂可选自芳香烃，优选含8-12个碳原子，如二甲苯混合物或取代的苯，酞酸酯类，如酞酸二丁酯或酞酸二辛酸，脂肪烃类，如环已烷或石蜡，醇和乙二醇和它们的醚和酯，如乙醇，乙二醇，乙二醇单甲基；酮类，如环已酮，强极性的溶剂，如N-甲基-2-吡咯烷酮，二甲基亚砜或二甲基甲酰胺，和植物油或植物油，如大豆油。
上述的固体载体，如用于悬浮剂和可分散剂的通常是天然矿物填料，例如滑石、高岭土，蒙脱石或活性白土。为了管理组合物的物理性能，也可以加入高分散性硅酸或高分散性吸附聚合物载体，例如粒状吸附载体或非吸附载体，合适的粒状吸附载体是多孔型的， 如浮石、皂土或膨润土；合适的非吸附载体如方解石或砂。另外，可以使用大量的无机性质或有机性质的预制成粒状的材料作为载体，特别是白云石。
根据本发明的组合物中的有效成分的化学性质，合适的表面活性剂为木质素磺酸、萘磺酸、苯酚磺酸、碱土金属盐或胺盐，烷基芳基磺酸盐，烷基硫酸盐，烷基磺酸盐，脂肪醇硫酸盐，脂肪酸和硫酸化脂肪醇乙二醇醚，还有磺化萘和萘衍生物与甲醛的缩合物，萘或萘磺酸与苯酚和甲醛的缩合物，聚氧乙烯辛基苯基醚，乙氧基化异辛基酚，辛基酚，壬基酚，烷基芳基聚乙二醇醚，三丁基苯聚乙二醇醚，三硬脂基苯基聚乙二醇醚，烷基芳基聚醚醇，乙氧基化蓖麻油，聚氧乙烯烷基醚，氧化乙烯缩合物、乙氧基化聚氧丙烯，月桂酸聚乙二醇醚缩醛，山梨醇酯，木质素亚硫酸盐废液和甲基纤维素。
本发明的组合物可应用在农业领域调节作物生长及防治作物病害方面。本发明中的植物包括但不限于水稻、黄瓜或香蕉等作物。
本发明的组合物中两种有效成分表现为互相促进作用，该组合物的活性比使用单个化合物的活性预期总和，本发明物中植调剂可促进植物生长调节，杀菌剂组分可以有效地杀灭病原物。在作物发生病害时，用该组合物处理作物，可有效防治病原物的扩散与传播，可有更好更快地防治作物病害，减轻因用药给作物带来的影响。本发明的组合物的表现出的其它特点主要表现为：1、本发明的组合物混配具有明显的协同相加作用，可相互促进效果；2由于本组合物的两个单剂化学结构差异很大，作用机理完全不同，不存在交互抗性，对作物安全，且可较大提升的防病效果；3本组合物减少因用药给作物生长带来的不良影响；4本组合物可提高作物产量，提升品质，具有较高的经济价值。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，以下结合实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅用以解释本发明，并不用于限定本发明，凡在本发明的精神和原则之内所做的任何修改、等同替换和改进等，均应包含在本发明的保护范围之内。
以下实施例所有配方中百分比均为重量百分比(折百)。本发明组合物各种制剂的加工工艺均为现有技术，根据不同情况可以有所变化。
一、剂型制备实施例
(一)悬浮剂的加工及实施例
将有效成分和助剂按照一定比例进行混合，再进行细磨后即可制成噻苯隆·嘧菌酯悬浮剂、噻苯隆·啶氧菌酯悬浮剂及噻苯隆·吡唑醚菌酯悬浮剂。
实施例1：48％噻苯隆·嘧菌酯悬浮剂
噻苯隆0.2％，嘧菌酯47.8％，黄原胶4％，膨润土3％，硅酸铝镁2％，乙二醇2％，木质素磺酸钠7％,水补足至100％。
实施例2：19％噻苯隆·嘧菌酯悬浮剂
噻苯隆0.1％，嘧菌酯18.9％，膨润土4％，丙三醇3％，甲基萘磺酸钠甲醛缩合物5％，水补足至100％。
实施例3:23％噻苯隆·嘧菌酯悬浮剂
噻苯隆0.2％，嘧菌酯22.8％，白炭黑3％，丙三醇6％，苯甲酸钠2％，脂肪醇聚氧乙烯醚磷酸酯7％,水补足至100％。
实施例4：48％噻苯隆·啶氧菌酯悬浮剂
噻苯隆0.2％，啶氧菌酯47.8％，黄原胶4％，膨润土3％，硅酸铝镁2％，乙二醇2％，木质素磺酸钠7％,水补足至100％。
实施例5：19％噻苯隆·啶氧菌酯悬浮剂
噻苯隆0.1％，啶氧菌酯18.9％，膨润土4％，丙三醇3％，甲基萘磺酸钠甲醛缩合物5％，水补足至100％。
实施例6:23％噻苯隆·啶氧菌酯悬浮剂
噻苯隆0.2％，啶氧菌酯22.8％，白炭黑3％，丙三醇6％，苯甲酸钠2％，脂肪醇聚氧乙烯醚磷酸酯7％,水补足至100％。
实施例7：48％噻苯隆·吡唑醚菌酯悬浮剂
噻苯隆0.2％，吡唑醚菌酯47.8％，黄原胶4％，膨润土3％，硅酸铝镁2％，乙二醇2％，木质素磺酸钠7％,水补足至100％。
实施例8：19％噻苯隆吡唑醚菌酯悬浮剂
噻苯隆0.1％，吡唑醚菌酯18.9％，膨润土4％，丙三醇3％，甲基萘磺酸钠甲醛缩合物5％，水补足至100％。
实施例9:23％噻苯隆·吡唑醚菌酯悬浮剂
噻苯隆0.2％，吡唑醚菌酯22.8％，白炭黑3％，丙三醇6％，苯甲酸钠2％，脂肪醇聚氧乙烯醚磷酸酯7％,水补足至100％。
(二)水乳剂的加工及实施例
将有效成分噻苯隆和嘧菌酯、啶氧菌酯及吡唑醚菌酯三者其中一种与溶剂、乳化剂、流动相等按照比例混合，精磨砂和高速剪切后，得到半成品，在进行加工成成品。
实施例10：41％噻苯隆·嘧菌酯水乳剂
噻苯隆0.2％，嘧菌酯40.8％，4％环己酮、6％二甲苯、15％十二烷基苯磺酸钙，水补足至100％。
实施例11：16％噻苯隆·嘧菌酯水乳剂
噻苯隆0.2％，嘧菌酯15.8％，4％甲醇、5％二甲苯、12％二苄基联苯基聚氧乙烯醚，水补足至100％。
实施例12：15％噻苯隆·嘧菌酯水乳剂
噻苯隆0.1％，嘧菌酯14.9％，4％环己酮、6％二甲苯、13％苯乙烯基苯基聚氧乙烯醚，水补足至100％。
实施例13：41％噻苯隆·啶氧菌酯水乳剂
噻苯隆0.2％，啶氧菌酯40.8％，4％环己酮、6％二甲苯、15％十二烷基苯磺酸钙，水补足至100％。
实施例14：16％噻苯隆·啶氧菌酯水乳剂
噻苯隆0.2％，啶氧菌酯15.8％，4％甲醇、5％二甲苯、12％二苄基联苯基聚氧乙烯醚，水补足至100％。
实施例15：15％噻苯隆·啶氧菌酯水乳剂
噻苯隆0.1％，啶氧菌酯14.9％，4％环己酮、6％二甲苯、13％苯乙烯基苯基聚氧乙烯醚，水补足至100％。
实施例16：41％噻苯隆·吡唑醚菌酯水乳剂
噻苯隆0.2％，吡唑醚菌酯40.8％，4％环己酮、6％二甲苯、15％十二烷基苯磺酸钙，水补足至100％。
实施例17：16％噻苯隆·吡唑醚菌酯水乳剂
噻苯隆0.2％，吡唑醚菌酯15.8％，4％甲醇、5％二甲苯、12％二苄基联苯基聚氧乙烯醚，水补足至100％。
实施例18：15％噻苯隆·吡唑醚菌酯水乳剂
噻苯隆0.1％，吡唑醚菌酯14.9％，4％环己酮、6％二甲苯、13％苯乙烯基苯基聚氧乙烯醚，水补足至100％。
(三)可湿性粉剂加工及实施例
将有效成分噻苯隆与嘧菌酯、啶氧菌酯及吡唑醚菌酯三种中的其中一种与各种助剂及填料等按比例充分混合，经超细粉碎机粉碎后制得可湿性粉剂。
实施例19：35％噻苯隆·嘧菌酯可湿性粉剂
噻苯隆0.8％，嘧菌酯34.2％，十二烷基苯磺酸钠5％，木质素磺酸钙3％，膨润土3％，凹凸棒土补足至100％。
实施例20：29％噻苯隆·嘧菌酯可湿性粉剂
噻苯隆1％，嘧菌酯28％，拉开粉3％，膨润土1.5％，烷基聚氧乙基醚磺酸盐2％，白炭黑2％，硅藻土补足至100％。
实施例21：18％噻苯隆·嘧菌酯可湿性粉剂
噻苯隆3％，嘧菌酯15％，木质素磺酸钠3％，烷基磺酸盐5％，白炭黑10％，高岭土补足至100％。
实施例22：35％噻苯隆·啶氧菌酯可湿性粉剂
噻苯隆0.8％，啶氧菌酯34.2％，十二烷基苯磺酸钠5％，木质素磺酸钙3％，膨润土3％，凹凸棒土补足至100％。
实施例23：29％噻苯隆·啶氧菌酯可湿性粉剂
噻苯隆1％，啶氧菌酯28％，拉开粉3％，膨润土1.5％，烷基聚氧乙基醚磺酸盐2％，白炭黑2％，硅藻土补足至100％。
实施例24：18％噻苯隆·啶氧菌酯可湿性粉剂
噻苯隆3％，啶氧菌酯15％，木质素磺酸钠3％，烷基磺酸盐5％，白炭黑10％，高岭土补足至100％。
实施例25：35％噻苯隆·啶氧菌酯可湿性粉剂
噻苯隆0.8％，啶氧菌酯34.2％，十二烷基苯磺酸钠5％，木质素磺酸钙3％，膨润土3％，凹凸棒土补足至100％。
实施例26：29％噻苯隆·吡唑醚菌酯可湿性粉剂
噻苯隆1％，吡唑醚菌酯28％，拉开粉3％，膨润土1.5％，烷基聚氧乙基醚磺酸盐2％，白炭黑2％，硅藻土补足至100％。
实施例27：18％噻苯隆·吡唑醚菌酯可湿性粉剂
噻苯隆3％，吡唑醚菌酯15％，木质素磺酸钠3％，烷基磺酸盐5％，白炭黑10％，高岭土补足至100％。
(四)可溶性液剂加工及实施例
按比例称取噻苯隆原药与啶氧菌酯原药或吡唑醚菌酯或嘧菌酯原药中一种，与助剂和水，置于反应瓶中，在20℃～100℃水浴条件下，充分搅拌直至获得透明液体，即得可 溶液剂。
实施例28：11％噻苯隆·嘧菌酯可溶性液剂
噻苯隆1％，嘧菌酯10％，环己酮15％，氮氮二甲基甲酰胺5％,乙二醇5％,水补足至100％。
实施例29：11％噻苯隆·啶氧菌酯可溶性液剂
噻苯隆原药1％，啶氧菌酯10％，氮酮5％，乳化剂吐温10％，环己酮12％，乙二醇5％,水补足至100％。
实施例30：11％噻苯隆·吡唑醚菌酯可溶性液剂
噻苯隆原药1％，吡唑醚菌酯10％，脂肪醇聚氧乙烯醚磷酸酯7％，异丙醇12％，乙二醇5％，尿素5％，水补足至100％。
二、药效验证试验
1、噻苯隆与甲氧基丙烯酸酯类杀菌剂复配对水稻生长调节及防病综合测定试验
将噻苯隆与甲氧基丙烯酸酯类杀菌剂用丙酮按照一定浓度稀释，对作物进行喷雾，在田间测定各个浓度对作物生长的影响，包括对作物的株高、纹枯病防治率、稻瘟病防治率及产量情况等进行综合评价。
株高提高率＝(清水对照株高-处理后的株高)/清水对照株高*100％
防病效果提高率＝(清水对照的发病指数-处理后的发病指数)/清水对照的发病指数*100％
千粒重提高率＝(处理的千粒重-清水对照的千粒重)/清水对照的千粒重*100％
亩产量提高率＝(处理后的亩产量-清水对照的亩产量)/清水对照的亩产量*100％
表1.噻苯隆与甲氧基丙烯酸酯类杀菌剂复配对水稻生长调节及防病汇总表
Figure PCTCN2017092640-appb-000005
Figure PCTCN2017092640-appb-000006
注：施药时期：在水稻稻瘟病和纹枯病发病初期施药。
通过实验发明人发现，噻苯隆与甲氧基丙烯酸酯类杀菌剂之间具有很好协同提升作用，噻苯隆与甲氧基丙烯酸酯类杀菌剂混配在不同配比下，相对噻苯隆、甲氧基丙烯酸酯类杀菌剂单剂，以及清水对照，对水稻的生长调节作用明显，主要表现在：控制水稻株高、提高水稻千粒重、提升水稻亩产量；喷施该发明组合物后，发病率大幅度降低，提升防病效果。
2、噻苯隆与甲氧基丙烯酸酯类杀菌剂混配对黄瓜的田间综合试验
将噻苯隆与甲氧基丙烯酸酯类杀菌剂用丙酮按照一定浓度稀释，对作物进行喷雾，在田间测定各个浓度对作物生长的影响，包括对作物的茎粗、霜霉病、白粉病发病率及产量情况等进行综合评价。
茎粗提高率＝(清水对照茎粗-处理后的茎粗)/清水对照茎粗*100％
防病效果提高率＝(清水对照的发病指数-处理后的发病指数)/清水对照的发病指数*100％
单株座果提高率＝(处理的单株座果-清水对照的单株坐座果)/清水对照的单株座果率*100％
水分含量提高率＝(处理后的水分含量-清水对照的水分含量)/清水对照的水分含量*100％
表2.噻苯隆与甲氧基丙烯酸酯类杀菌剂复配对黄瓜的综合测定汇总表
Figure PCTCN2017092640-appb-000007
Figure PCTCN2017092640-appb-000008
从表2实验数据显示，本发明的产品在黄瓜霜霉病及白粉病发病初期施药，在黄瓜霜霉病及白粉病发生时，可有效降低病情指数，提高防治效果；可有效促进黄瓜茎增粗；提高黄瓜单株座果率，提升黄瓜水分含量，提高黄瓜品质。

Claims (10)

  1. 一种植物生长调节剂与杀菌剂的组合物，其特征在于该组合物包含A和B两种活性组分，其中活性组分A为噻苯隆，活性组分B选自嘧菌酯、啶氧菌酯或吡唑醚菌酯，活性组分A和活性组分B的重量比为1：240～5。
  2. 根据权利要求1所述的组合物，其特征在于活性组分A噻苯隆和活性组分B的重量比为1：210～20。
  3. 根据权利要求1所述的组合物，其特征在于活性组分A噻苯隆和活性组分B的重量比为1：204～10。
  4. 根据权利要求1所述的组合物，其特征在于活性组分嘧菌酯和活性组分嘧菌酯的重量比为1：204～10。
  5. 根据权利要求1所述的组合物，其特征在于活性组分噻苯隆和活性组分啶氧菌酯或吡唑醚菌酯的重量比为1：204～10。
  6. 根据权利要求1～5中任意一项所述的组合物，其特征在于该组合物由活性成分和助剂制成农药上允许的剂型。
  7. 根据权利要求6所述的组合物，其特征在于该组合物中的活性成分的质量含量为5～85％。
  8. 根据权利要求6所述的组合物，其特征在于所述剂型为悬浮剂、水乳剂、可湿性粉剂等农业领域允许剂型。
  9. 权利要求1～5中任意一项所述的组合物在农业领域调节作物生长及防治作物病害方面的应用。
  10. 根据权利要求9所述的用途，其特征在于所述作物选自水稻、黄瓜或香蕉。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118303419A (zh) * 2024-06-06 2024-07-09 黑龙江省农业科学院水稻研究所 一种用于防治水稻真菌性病害的组合物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106359430A (zh) * 2016-08-22 2017-02-01 江苏辉丰农化股份有限公司 一种农药组合物
CN106922683A (zh) * 2017-03-21 2017-07-07 江苏辉丰农化股份有限公司 含有苯并异噻唑啉酮和噻苯隆的农药组合物
CN112514909A (zh) * 2020-12-17 2021-03-19 多农多收技术研究(江苏)有限公司 一种增产组合物、增产药剂及其应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101203131A (zh) * 2005-06-22 2008-06-18 先正达参股股份有限公司 组合物及方法
CN102180871A (zh) * 2011-03-24 2011-09-14 南开大学 4-甲基-1,2,3-噻二唑脲类衍生物及其制备方法和用途
CN105307497A (zh) * 2013-06-18 2016-02-03 巴斯夫欧洲公司 包含嗜球果伞素型杀真菌剂的杀真菌混合物i
CN105475315A (zh) * 2015-12-18 2016-04-13 广东中迅农科股份有限公司 含有吡唑醚菌酯和萘乙酸的农药组合物
CN105594720A (zh) * 2015-12-18 2016-05-25 广东中迅农科股份有限公司 含有吡唑醚菌酯和芸苔素内酯的农药组合物
CN106359430A (zh) * 2016-08-22 2017-02-01 江苏辉丰农化股份有限公司 一种农药组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000076729A (ko) * 1999-03-03 2000-12-26 해슬러 요세 수면 적용용 농약 제제
JP5433120B2 (ja) * 1999-09-30 2014-03-05 モンサント テクノロジー エルエルシー 向上した安定性を有するパッケージミックス農薬組成物
CN103314968B (zh) * 2013-06-09 2014-09-17 江苏辉丰农化股份有限公司 具有增效作用的杀菌组合物
CN105494387B (zh) * 2015-12-16 2018-05-11 江苏辉丰农化股份有限公司 一种农药组合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101203131A (zh) * 2005-06-22 2008-06-18 先正达参股股份有限公司 组合物及方法
CN102180871A (zh) * 2011-03-24 2011-09-14 南开大学 4-甲基-1,2,3-噻二唑脲类衍生物及其制备方法和用途
CN105307497A (zh) * 2013-06-18 2016-02-03 巴斯夫欧洲公司 包含嗜球果伞素型杀真菌剂的杀真菌混合物i
CN105475315A (zh) * 2015-12-18 2016-04-13 广东中迅农科股份有限公司 含有吡唑醚菌酯和萘乙酸的农药组合物
CN105594720A (zh) * 2015-12-18 2016-05-25 广东中迅农科股份有限公司 含有吡唑醚菌酯和芸苔素内酯的农药组合物
CN106359430A (zh) * 2016-08-22 2017-02-01 江苏辉丰农化股份有限公司 一种农药组合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118303419A (zh) * 2024-06-06 2024-07-09 黑龙江省农业科学院水稻研究所 一种用于防治水稻真菌性病害的组合物

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