WO2018088926A1 - Cardioqvark cardiac monitor with integral two-channel photoplethysmograph - Google Patents

Abstract

The utility model relates to the fields of medicine and accessories for mobile devices, such as mobile phones, smartphones, personal digital assistants (communicators) with mobile telephone functions, the iPhone or any other devices operating on a Windows, Android, iOS or other platform, having a digital or analogue interface, and is directed toward improving measuring accuracy and the reliability of diagnostic information provided regarding cardiac function and the condition of a person's vascular system, which makes it possible to observe a cardiac signal, a pacemaker signal and the shape of the pulse wave directly on the screen of a mobile device, increases the possibility of the comprehensive diagnosis of internal diseases by cross-correlating data, and improves the accuracy with which cardiovascular disease sites are localized. This technical result is achieved in a device for simultaneously obtaining a cardiogram and a plethysmogram from regions of a person's body (for example, from two limbs) using a mobile device, the claimed device being in the form of a case for mobile devices, in which are mounted two electrode sensors for recording an ECG, said sensors being connected to a differential amplifier, and two sensors for recording a PPG, which are connected to a controller that is connected to a power supply, a cryptoprocessor and an analog-to-digital converter (ADC) and is capable of transmitting data via an interface (any available digital or analogue interface) to a mobile device, wherein the ADC is capable of receiving data from the differential amplifier, and the PPG sensors are capable of being connected to the controller via a digital control bus and of transmitting data.

Description

 Two-Channel Cardiomonitor

 CARDIOQVARK PHOTO PLAYMOGRAPHER The utility model relates to medicine, in particular to devices for receiving a cardiogram and photoplethysmogram, as well as to the field of accessories for mobile devices - mobile phones, smartphones, personal digital assistants (PDAs) with the functions of a mobile phone, iPhone or any another device that runs on the platform of Windows, Android, iOS or another, and is designed to simultaneously register a cardiogram and two-channel photoplethysmogram using devices that have x digital or analog interface.

 As the closest analogue of the claimed utility model, one can take a cardiogram device made in the form of a case-cover for mobile devices containing electric field sensors, each of which is connected to a differential amplifier and a potentiometer controlled by a controller connected to a crypto processor, a power source, analog-to-digital converter (ADC) and transmitting information via USB to a mobile device, while the ADC receives information from a differential amplifier (RU 162018, 05.20.2016).

 The technical problem to which the proposed utility model is directed is to create a device for simultaneously receiving a cardiogram and photoplethysmogram from two limbs or other parts of the human body using mobile devices, the parameters of which provide data synchronously with the cardiogram about pulse wave parameters from two limbs and the ability to observe an electrocardiogram (ECG) and two photoplethysmograms (PPG) on the screen of a mobile device.

The technical result achieved by the implementation of this utility model is to increase the operational characteristics of the product as a whole by providing simultaneous registration together with a cardiogram of two PPG signals from different parts of the body and transferring them to a mobile device by connecting via any available digital or analog interface, this device simultaneously transmits in real time an ECG signal digitized with a frequency of 20 kHz and two independent PPG signals, frequency-matched with EC . Digitization of data with a high frequency can significantly increase the reliability of the information received on cardiac activity, the state of blood vessels, and It also makes it possible to observe the cardiac signal, the pacemaker signal and the pulse wave shape directly on the screen of the mobile device, which leads to an increase in the device’s performance and also to the expansion of the device’s functionality, since the registration of two PPG signals synchronized with the ECG expands the possibilities of complex diagnosis of internal diseases due cross-correlation of data and increases the accuracy of localization of foci of cardiovascular diseases.

 The specified technical result is achieved in a device for simultaneously receiving a cardiogram and photoplethysmogram from parts of the human body (for example, from two limbs) using mobile devices, made in the form of a case-cover for mobile devices, in which two sensor electrodes for recording ECG connected to differential amplifier; two sensors for registering FIGs, connected to a controller associated with a crypto processor, a power source and an analog-to-digital converter (ADC) and configured to transmit information via an interface (to any available digital or analog interface) to a mobile device, while the ADC is configured to receiving information from a differential amplifier, and the PPG sensors are configured to communicate with the controller via a digital control and data transmission bus.

 A device for simultaneously receiving a cardiogram and photoplethysmogram from parts of the human body using mobile devices is configured to receive a cardiogram according to standard cardiological lead I.

 A device for simultaneously receiving a cardiogram and photoplethysmogram from sections of the human body using mobile devices is configured to receive a photoplethysmogram in reflected light.

 A device for simultaneously receiving a cardiogram and photoplethysmogram from sections of the human body using mobile devices is configured to register a cardiogram and two channels of the photoplethysmogram synchronously.

The sensor electrode for recording ECG is a plate of conductive material with a pre-treated surface, which allows reliable recording of bioelectric potentials of the heart from parts of the human body without the use of gels and conductive compounds. Each sensor an electrode for recording an ECG is structurally combined with an FPG sensor, forming two blocks for recording physiological parameters.

 The sensor for detecting PPG is an integrated module containing emitters of the red range, infrared range, a photodetector matched to them by the passband, a data preprocessing unit, and an interface for exchange via a standard digital bus.

 Sensors-electrodes for recording ECG and sensors for detecting PPG are rigidly fixed / built into a printed circuit board made with electronic components and installed in a case-cover for mobile devices, which is a protective non-conductive case. The printed circuit board is a shielding element through its metallization. Sensors-electrodes for recording ECG and sensors for registering PPG can be made with the possibility of connection to the printed circuit board using remote cables.

 The ADC is configured to process the signals received through the differential amplifier from the sensor electrodes to record the ECG, and to digitize the signals for transmission to the controller.

 The controller executes the program algorithm laid down, issues control signals to the device’s functional units, coordinates their operation, sets the operating modes, manages the power supply, receives ADC data from sensor electrodes for ECG registration, receives digital data from sensors for PPG registration and processes them, makes data exchange with mobile devices via the interface, performs self-diagnostics.

 The power source is a direct current power source and is program-controlled, with the function of stabilizing and converting a unipolar supply voltage to a series of voltages to power functional units, including the formation of bipolar voltage; with the possibility of partial disconnection of consumers in low power mode.

 The crypto processor ensures the correct operation of the device with Apple products.

As an interface for exchanging data with mobile devices, the USB port is used, which has a splitter with an automatic switch to one of two external devices, while the USB port also serves to supply external power to the device, or as interfaces for data exchange with external devices used wireless transmission channels, including, but not limited to: radio frequency, light, acoustic and air (gas) non-acoustic range.

 The case-cover for mobile devices is made with holes for access to sensors-electrodes for ECG registration and sensors for registration of PPG and has a back wall, end walls and side walls or part of the side walls, and is also made with a loop connection for direct connection to the processor mobile device through the connector of the mobile device and is designed to work with external or autonomous power supply.

 Using the design of the utility model, characterized by the features of an independent claim, allows synchronously registering together with a cardiogram two photoplethysmogram signals from different parts of the body and transmitting in real time an ECG signal digitized at a frequency of 20 kHz and two independent PPG signals frequency-matched with an ECG a mobile device, which can significantly increase the reliability of the information received on cardiac activity, the state of blood vessels and the ability to observe cardi the signal, the signal of the pacemaker and the pulse wave form directly on the screen of the mobile device. Thus, the registration of two PPG signals synchronous with the ECG increases the accuracy of localization of foci of cardiovascular diseases, which increases the operational characteristics of the product as a whole and expands the possibilities of a comprehensive diagnosis of internal diseases due to the cross-correlation of data.

 The invention is illustrated by the drawing, which shows a block diagram of a cardiomonitor combined with a two-channel photoplethysmograph.

Registration of a cardiogram is carried out, for example, from the fingers and / or other parts of the human body using two (dry) sensor electrodes for recording ECG 1 made of conductive material. From them, the signal is fed to differential amplifier 2, and then to the processing in ADC 3. The digitized signal is fed to the controller 4. Registration of the photoplethysmogram is carried out in reflected light also from the fingers and / or other parts of the human body at the same time with two sensors for recording FIG 5. The sensor for registering FIG 5 is a module that combines a red light emitter, an infrared light emitter, a photodetector matched to them in the passband, a pre-driver circuit th processing and digital interface for data exchange with the controller. Each sensor for recording ECG 1 can be structurally combined with a sensor for registering FIG 5. The design of such a group of sensors 1, 5 is a conductive sensor electrode for recording ECG 1, in which there is an opening for emitters and a photodetector of a sensor for registering FIG 5. Sensors 1, 5 are rigidly built into the printed circuit board or have the option of removal on an extension cable. Crypto processor 6 provides legitimacy for working with Apple devices. From controller 4, information is received via any available digital or analog interface 7 to a mobile device (external device) running on a platform of Windows, Android, iOS, or another. The device is powered from a built-in or external power supply 8, in one implementation, through a USB port, and the USB port has a splitter with an automatic switch to one of two external devices. The power supply is controlled by the controller. Primary voltage +2.5 ... +5 V is converted into a series of stabilized voltages +1.8; +3.3; + 4.25 V to power digital circuits, and, in addition, when the ECG recording mode is turned on, a voltage of +3.3 V is output to power the analog part of the device. Implemented the ability to disable one or more voltage regulators to reduce power consumption. A printed circuit board with electronic components and sensors is housed in a protective, non-conductive housing. Access to the sensors is organized through openings in the device case or the sensors are fed to the measurement site by remote cables. Screening of the device is carried out using metallization of the printed circuit board.

For the cardiomonitor to work with a two-channel photoplethysmograph, it is necessary to install the CardioQVARK program on the mobile device, equipped with a convenient interface. It allows you to easily remove a cardiogram and photoplethysmogram yourself, without the help of medical staff. Just start the program and enter the data capture mode. The case-cover must be worn on a mobile device and / or connected to it by a cable, a wireless channel. Next, you need to attach your fingers to two groups of sensors or bring groups of sensors using remote cables to other areas on the body. After starting recording, calibration will start first. Calibration time can be set by yourself. Then, the data acquisition mode will be switched on directly, the duration of which is from 3 to 5 minutes, this time is enough to accurately capture the signals formed by the heart and blood vessels. Then the program will offer to send data to the server. After processing the information, the result is displayed on the screen of the mobile device with data on cardiac activity, such as heart rate, uneven heartbeat, power of high and low frequency spectra, heart rate indicator and so on and data on the state of blood vessels, as well as the degree of blood saturation oxygen, blood pressure and other measured and calculated parameters. Information is displayed in an accessible form: in separate tabs of the program, you can view the calculated data on violations of the normal rhythm due to extraordinary heart contractions, the ratio of inhibitory and exciting processes of regulation of the nervous system, the effect of hormonal regulation of the body on the heart. It also assesses the effect of the nervous system on the heart, mobilization of internal resources, the body's ability to adapt to mental and physical stress. At the same time, information is given on the shape of the pulse wave, an assessment of the degree of elasticity and endothelial function of various groups of vessels, respiratory rate, and other related physiological parameters. At the same time, there is always access to the data of previous studies in the special “Health Card”, which the program is equipped with. It contains all the information indicating the date and time of simultaneous removal of the cardiogram and photoplethysmograms.

 A distinctive feature of this cardiomonitor with a two-channel photoplethysmograph is real-time online monitoring: information is sent to the server, and then after its processing, directly to the attending physician. Thus, the doctor can monitor the patient’s condition, even while being at a distance, and provide expert advice remotely. This may be especially true for those patients who are at a considerable distance from medical facilities and sometimes do not have the opportunity to quickly receive medical advice in person. In addition, dry contact non-invasive sensors are used in the device, due to which physiological parameters are recorded in conditions comfortable for the patient, without the use of clamps and consumables. When conducting functional studies with such a device, there is no need for special preparation of the patient. This makes it possible to significantly speed up and simplify the collection of results and the diagnosis of cardiovascular and a number of other diseases in order to prescribe a further course of treatment.

Claims

Utility Model Formula  1. A device for simultaneously receiving a cardiogram and photoplethysmogram from parts of the human body using mobile devices, characterized in that it is made in the form of a housing-cover for mobile devices, in which two sensor electrodes for recording an electrocardiogram (ECG) connected to a differential an amplifier; two sensors for recording photoplethysmograms (PPG) connected to a controller connected to a cryptoprocessor, a power source and an analog-to-digital converter (ADC) and configured to transmit information via an interface to a mobile device, while the ADC is configured to receive information from a differential amplifier and FPG sensors are configured to communicate with the controller via a digital control and data transmission bus.  2. The device according to claim 1, characterized in that it is made with the possibility of obtaining a cardiogram according to standard cardiological lead I.  3. The device according to p. 1, characterized in that it is made with the possibility of obtaining photoplethysmogram in reflected light.  4. The device according to claim 1, characterized in that it is configured to register a cardiogram and two channels of the photoplethysmogram synchronously.  5. The device according to claim 1, characterized in that the sensor electrode for recording the ECG is a plate of conductive material with a pre-treated surface, which allows reliable recording of the bioelectric potentials of the heart from parts of the human body without the use of gels and conductive compositions.  6. The device according to claim 1, characterized in that the sensor for detecting PPG is an integrated module containing emitters of the red range, infrared range, a photodetector matched to them by the passband, a data preprocessing unit and an interface for exchange via a standard digital bus. 7. The device according to p. 5, characterized in that each sensor electrode for recording an ECG is structurally combined with a PPG sensor, forming two units for recording physiological parameters. 8. The device according to p. 1, characterized in that the ADC is configured to process signals supplied to it through a differential amplifier from sensor electrodes for ECG registration, and digitizing the signals for transmission to the controller.  9. The device according to claim 1, characterized in that the controller executes the programmed algorithm, implements control signals to the device’s functional units, coordinates their work, sets the operating modes, manages the power, receives data from the sensor electrodes from the ADC for ECG registration, receives to the digital bus, data from sensors for registering FIGs and processes them, exchanges data with mobile devices via an interface, and performs self-diagnostics.  10. The device according to claim 1, characterized in that the power source is a direct current power source and is program-controlled, with the function of stabilizing and converting a unipolar supply voltage to a series of voltages to power functional units, including the formation of bipolar voltage; with the possibility of partial disconnection of consumers in low power mode.  1 1. The device according to claim 1, characterized in that the cryptoprocessor ensures the correct operation of the device with Apple products.  12. The device according to claim 1, characterized in that a USB port is used as an interface for exchanging data with mobile devices, having a splitter with an automatic switch to one of two external devices, while the USB port also serves to supply external power to the device .  13. The device according to claim 7, characterized in that the electrode sensors for recording ECG and sensors for detecting PPG are rigidly integrated into a printed circuit board made with electronic components and installed in a case-cover for mobile devices, which is a protective non-conductive case.  14. The device according to p. 13, characterized in that the printed circuit board is a shielding element through its metallization. 15. The device according to p. 13, characterized in that the case-cover for mobile devices is made with holes for access to the sensor electrodes for ECG registration and sensors for registering PPG. 16. The device according to p. 15, characterized in that the housing for mobile devices has a rear wall, end walls and side walls or part of the side walls.  17. The device according to p. 16, characterized in that the housing is a case for mobile devices made with a loop connection for direct connection to the processor of the mobile device through the connector of the mobile device.  18. The device according to p. 17, characterized in that the housing-cover for mobile devices is made with an autonomous power source.  19. The device according to claim 1, characterized in that wireless transmission channels are used as interfaces for exchanging data with external devices.  20. The device according to p. 19, characterized in that the wireless transmission channels are selected from the group: radio frequency, light, acoustic and air non-acoustic range.  21. The device according to p. 12 or p. 19, characterized in that the interface is a digital or analog interface.