[go: up one dir, main page]

WO2018083221A1 - Piston fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale et seringue médicale - Google Patents

Piston fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale et seringue médicale Download PDF

Info

Publication number
WO2018083221A1
WO2018083221A1 PCT/EP2017/078154 EP2017078154W WO2018083221A1 WO 2018083221 A1 WO2018083221 A1 WO 2018083221A1 EP 2017078154 W EP2017078154 W EP 2017078154W WO 2018083221 A1 WO2018083221 A1 WO 2018083221A1
Authority
WO
WIPO (PCT)
Prior art keywords
piston
sealing lip
diameter
section
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2017/078154
Other languages
German (de)
English (en)
Inventor
Ronny Prosper Elisabeth Vrijens
Norbert Haberland
An Vanheel
Raphael KÄLIN
Thomas Cuyvers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Datwyler Pharma Packaging Belgium NV
Original Assignee
Datwyler Pharma Packaging International NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Datwyler Pharma Packaging International NV filed Critical Datwyler Pharma Packaging International NV
Publication of WO2018083221A1 publication Critical patent/WO2018083221A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31521—Pistons with a forward extending skirt at their front end

Definitions

  • the invention relates first to a produced by plastic injection syringe piston for a medical syringe and further medical syringe see a syringe with a piston, wherein the piston has one or more sealing lips, further wherein a sealing lip in cross-section to the front or to the rear is swept to a given for the application of liquid from the syringe in use feed direction.
  • Pistons of the type in question are known. These find particular use in medical syringes for administration or withdrawal of fluids to or from a patient, further, for example, as also preferred below, in syringes with a cylindrical body. Between the piston and the inner wall surface of the cylindrical syringe body, a liquid-tight seal is required. For this purpose it is known, on the piston, in particular with respect to the aligned in the feed direction
  • a line penetrating the sealing lip in its direction extending outward from the piston outer wall encloses an acute angle of less than 90 °, in particular less than 75 °.
  • piston 10 2005 003 516 B3, wherein the piston consists of an elastically deformable material and has circumferentially exposed by a longitudinal step-shaped configuration of the piston wall exposed sealing lips.
  • EP 2 817 043 B1 relates to such a piston with back-swept sealing lips.
  • a piston produced by two-component injection molding which consists of a soft, elastomeric thermoplastic on the outside, forming a sealing lip which is swept to the front.
  • the invention has the object to further improve a piston of the type in question.
  • a possible solution to the problem is given according to a first inventive concept in a piston, in which it is geared to the fact that the piston in the plastic injection molding process is made of a fluorine-based plastic material.
  • the fluorine-based plastic material offers advantages, in particular with regard to the frictional force between the piston and the inner wall surface of the syringe barrel. It is a thermoplastic material. The friction force is noticeably reduced in comparison to a piston made of an elastomer material.
  • a piston in the proposed embodiment is very inert.
  • the elasticity of the plastic which is known from the plastic material selected over the elastomer material known from the prior art, such as, for example, rubber, is compensated by the design of the one or more sealing lips. At least the foremost sealing lip in the feed direction has a flexible behavior due to its swept orientation despite the comparatively hard plastic material.
  • Silicone oil or other materials that contain silicone oil components to form further free of "baked on” silicone oil and other non-silicone oil-containing coatings A preferred feature is therefore that the piston and / or the syringe with which the piston interacts free from Silicone oil is formed.
  • a swept orientation does not necessarily require, in the context of the invention, an extension of the sealing lip which is rectilinear in cross section. It can also be a curved, extending forward or backward design or an angled shape tion of the sealing lip may be formed with a corresponding extending forward or rearward area.
  • a compensation of tolerances with respect to the inner diameter of the syringe barrel can be achieved by the preferably swept alignment of one or the sealing lips. Even with the selected plastic still results in a certain penetrability to compensate for a smaller inner diameter.
  • fluorine-based plastic materials in particular fluorine-containing (co) polymers are used, such as. ETFE (ethylene tetrafluoroethylene), which has a high radiation resistance, for example. In the course of radiation sterilization with gamma rays.
  • ETFE ethylene tetrafluoroethylene
  • FEP perfluoroethylene propylene copolymer
  • Tetrafluoroethylene, hexafluoropropylene and vinylidene fluoride is characterized by a certain flexibility and / or a relatively high tensile strength, in particular over the materials further exemplified in particular during the molding process and / or a relatively low yield strength, which is particularly advantageous when inserting the piston in the syringe barrel. Furthermore, this material is characterized by a relatively low flexural modulus. This property can also be helpful for better compensation of dimensional tolerances in the area of Syringe barrel inner surface. It can be achieved as a constant contact pressure value and thus a favorable sealing performance.
  • PVF polyvinyl fluoride
  • exemplary materials within the meaning of the invention may also be perfluoroalkoxy polymers (PFA), polychlorotrifluoroethylene (PCTFE), ethylene enchlorotrifluoroethylene (ECTFE) and polyvinylidene fluoride (PVDF).
  • PFA perfluoroalkoxy polymers
  • PCTFE polychlorotrifluoroethylene
  • ECTFE ethylene enchlorotrifluoroethylene
  • PVDF polyvinylidene fluoride
  • an improvement in the electrical properties, such as, for example, a low dielectric constant can be detected by a high proportion of fluorine.
  • an increased fluorine content lowers the coefficient of friction, raises the melting point and increases the thermal stability of the plastic part.
  • the solubility of polymers in solvents decreases with the increase of fluorine content in the polymer molecule. Best properties are achieved when a polymer is completely fluorinated (eg perfluoroalkoxy polymers - PFA).
  • a further solution of the problem is given according to a further inventive idea in a piston, in which it is geared to that the piston is made in the plastic injection molding of a fluorine-based material and that the piston counter to the feed direction below a frontmost sealing lip largest Piston diameter forms and in that, viewed in a cross section, a channel formed by the swept-up sealing lip opposite a central region of the piston projects radially beyond the largest piston diameter.
  • the channel results from a gusset region between the piston section, on which the sealing lip is rooted, and an upper side of the piston
  • Sealing lip The swept in cross-section alignment of the sealing lip and thus also the top of the sealing lip leads to a cross-section preferably V-shaped channel.
  • a projection in the feed direction preferably extends a piston outer surface of the foremost in the feed direction below
  • Sealing lip adjoining portion of the piston viewed in an extension, within the groove, i. that the imaginary extension of the piston outer surface in the region below the foremost sealing lip, which then protrudes in the feed direction over the foremost sealing lip, the trough t. This results in a favorable support of the sealing lip, in particular in the direction opposite to the feed direction.
  • the piston in the case of a sweep of a sealing lip forward in the feed direction over a foremost portion of a front, swept forward forward sealing lip front portion has.
  • the protruding in the feed direction of the piston over the front in the feed direction sealing lip front portion of the piston leads to a favorable pressurization in the region of the piston surface. Also, this is a practically complete emptying of the syringe barrel reached.
  • the suitable design consists in particular in an adaptation to an inner contour of the syringe barrel in the region of the transition to the needle hub or to the outlet opening.
  • a conical design of the front portion is preferred with a central, in particular the piston longitudinal axis receiving, projecting in the feed direction and a leading outgoing circumferential and in cross section at an acute angle to a transverse plane to the longitudinal axis engaging surface.
  • the circumferential sealing lip in particular the front sealing lip, is also supported in its sealing action as a result of an advancing movement of the piston for dispensing a liquid.
  • the tip itself may be rounded in a contour.
  • the piston in the case of a backward sweep may have a given over a subsequent in the direction of the arrow cylindrical portion radial projection corresponding to one sixth or more to one third of the diameter of the cylindrical portion, wherein a Thickness of the supernatant in the direction of a longitudinal axis of the piston on one half of the radial projection of a six-axis tel or less up to a tenth or one twentieth of the diameter.
  • the pointing in the feed direction surface of the foremost, swept sealing lip can steplessly and evenly pass into the direction of feed in the end face of the piston, these mitressend corresponding, more preferably this forward facing in the feed direction end face of the piston is formed in a circular cone shape.
  • a plurality of sealing lips are formed in an axial direction of the piston, which can each be provided with the mentioned sweep.
  • two or three, moreover possibly more than three, so for example four or five circumferential sealing lips may be provided.
  • the forwardmost in the feed direction sealing lip preferably has a swept orientation. This can also be provided for all other sealing lips or only for a part of the other sealing lips.
  • all the circumferential sealing lips provided may have the same diameter, in particular those diameters which are chosen to be larger in order to obtain sufficient tightness than the internal diameter of the syringe cylinder receiving the piston.
  • a sealing lip is provided with a reduced diameter relative to the foremost sealing lip.
  • a sealing lip takes on less sealing tasks, but has a supporting effect of the piston on the cylinder inner wall. So can opposite the feed direction below the foremost sealing lip all other sealing lips have such a reduced diameter.
  • the reduced diameter may correspond to the inner diameter of the syringe barrel.
  • the front portion of the piston may have a curved contour in cross-section, wherein the contour line merges with a concave curvature in the foremost sealing lip.
  • the transition of the contour line may be in cross-section or formed within a largest piston diameter.
  • the piston can be made in one piece and the same material, without a given in the direction of feed direction mold parting line. Since the piston usually also has a coincident with the feed direction central axis, the characterization can be given that the piston is made without axial mold parting line. As a result, it can be achieved that no mold parting line is provided, which runs crosswise to a sealing lip. As at a mold parting line sometimes
  • the primary sealing region which is given in particular by a free end region of a frontmost sealing lip, is preferably a separating line. free.
  • a mold parting line extending transversely to the feed direction or a transverse to the central axis of the piston extends outside a region of a sealing lip with a radially largest extent. More preferably, the mold parting line is perpendicular to the feed direction or the central axis.
  • the mold parting line also preferably runs continuously in the same plane.
  • the relevant plane is perpendicular or nearly perpendicular to the feed direction or the central axis.
  • the mold parting line can further preferably on a rear or underside of a sealing lip, so facing away from a front free end of the piston run.
  • the undercut can be kept sufficiently low, so that the demoulding, possibly still increased over a subsequent state, given elastic deformability is sufficient to demold from the undercut, on the other hand, also form-technical precautions can be taken, such as obliquely to the central axis movable moldings are provided.
  • the mold parting line may be continuous, but in this case preferably offset relative to a sealing region of the sealing lip which is relevant in use. Nevertheless, the mold parting line may still be formed in the sealing lip itself, in the feed direction in front of or behind the relevant sealing region of the sealing lip.
  • the piston may, as also preferred, be integrally formed with the material or the material together with the one or more sealing lips.
  • the piston Sealing surface including the sealing lips is formed by the piston plastic material alone.
  • the piston may be made by plastic injection molding.
  • a sweep can also be achieved after removal from the mold, for example in cooperation with the piston having a hollow shape which has a correspondingly smaller inner diameter than corresponds to the outermost diameter of a sealing region.
  • the piston may be made entirely of a fluorine-based plastic material. Also possible is a combined piston design, for example a combination of two different fluoropolymer materials.
  • a piston core encapsulated with fluorine-based plastic material can also be provided, for example a metal core or a core consisting of another (non-fluorine-based) thermoplastic material or even of an elastomeric material (for example rubber).
  • the medical syringe with a cylindrical body in which a piston is inserted is provided with a piston having one or more of the features described above and below with respect to the piston.
  • the body of the medical syringe is preferably formed without an inner coating for increasing the lubricity, and more preferably, in particular, without a coating comprising silicone oil or silicone oil constituents.
  • the ranges and value ranges or multiple ranges given above and below also include all intermediate values, in particular in 1/10 increments of the respective dimension, if appropriate also without dimensions.
  • This disclosure can on the one hand to delimit an area mentioned limit from below and / or above, but alternatively or in addition to the disclosure of one or more singular values from a respective specified range serve.
  • Figure 1 is a partial sectional view of a medical syringe with a piston in a first embodiment.
  • FIG. 2a shows an embodiment of the piston according to FIG. 2 modified with regard to the front section
  • FIG. 3 shows the enlargement of region III in FIG. 2;
  • FIG. 4 shows the enlargement of the region IV in FIG. 2
  • FIG. 5 shows the piston according to FIG. 2 in a perspective illustration
  • Fig. 6 is a further perspective view of the piston according to
  • Fig. 7 is a representation corresponding to Figure 2, but a second
  • FIG. 8 shows the enlargement of the region VIII in FIG. 7;
  • FIG. 9 shows the enlargement of the region IX in FIG. 7;
  • Fig. 11 is another perspective view of the piston of the second embodiment
  • Fig. 12 is a sectional view according to Figure 7, concerning a further
  • Fig. 13 is a detail view of a piston showing a
  • Mold parting line in the area of a sealing lip.
  • the syringe 1 is composed essentially of an elongated cylinder open on both sides, in particular cylindrical body 2, and a piston 3 displaceable in the cylindrical body 2 in the feed direction r or counter to the feed direction r.
  • the cylindrical body 2 consists for example of glass, alternatively cyclo-olefin copolymer (COC) or cyclo-olefin polymer (COP), and has a distal end 4 and a proximal end 5. In the region of the distal end 4 of the cylindrical body 2 goes over a tip-shaped needle attachment 6.
  • a radial expansion in the form of a flange 7 is formed on the cylindrical body 2. This serves in the course of using the syringe 1 as a counter-holder to the lower handle preferably by the index and middle finger of the syringe 1 serving hand.
  • the piston 3 is connected to a piston rod 8. This passes through a provided in the proximal end 5 insertion opening 9 of the cylindrical body 2 and formed in the region of the free, the piston 3 end facing away from the longitudinal extent of the piston rod 8 aligned, plate-like thumb rest 10th
  • the piston rod 8 can, as shown, be formed in the form of cross-like arranged webs 11.
  • the piston 3 is described below with reference to various embodiments.
  • the piston 3 of all embodiments is manufactured in one piece in the plastic injection molding process, this further from a fluorine-based Plastic material, preferably according to a fluorine-containing (co) polymer.
  • the piston 3 has a longitudinal axis x, which coincides in the use state according to Figure 1 with the longitudinal axis of the cylindrical body 2.
  • a receiving opening 12 formed with an internal thread 13, for screw fixing the facing distal end of the piston rod eighth
  • the front section 14 may be designed conically in cross-section, preferably with a curvature transition assigned to the middle region, or further, for example, according to the illustrations in FIG. 2 or also FIG. 12 in a cross section in which the longitudinal axis x forms a line, having a curved contour, so that viewed from the piston 3 in the direction of the distal end 4, a convex protrusion of the piston 3 results.
  • the front section may also have, preferably starting from a central region of the piston and enclosing it, a flat region which extends at least partially approximately at right angles back on the longitudinal axis of the piston.
  • This section 15 merges into a rotationally symmetrical, cylindrical section 16 which, together with the front section 14, essentially determines the piston length considered in the extension direction of the longitudinal axis x.
  • the cylindrical portion 16 is provided with the receiving opening 12 and the internal thread 13.
  • the cylindrical section 16 adjoining the section 15 has a diameter d 'which can be chosen to be larger than the diameter d in the region of the front section-side cylindrical section 15.
  • the diameter d' can be approximately one , 1 to 1.5 times, further, for example, about 1.2 times the diameter d correspond.
  • the diameter d remains the same over the length of the section 16, with the exception of the sealing lip areas described below.
  • a step-like radial widening of the cylindrical section 16 is provided in the region of a central sealing lip with respect to the longitudinal extent. It turns out that way a further diameter dimension d "in the end region of the section 16 facing away from the front section 14, which diameter dimension d" is approximately 1.1 to 1.5 times, further approximately 1.2 times that at the front section 14 or cylindrical section 15 subsequent diameter measure d or d 'can correspond.
  • Each diameter d, d 'and optionally d " is dimensioned smaller than an inner diameter of the cylindrical body 2. Accordingly, the piston 3 with its portion 16, as well as the possibly formed cylindrical portion 15 preferably does not come with an inner surface of the cylindrical Body 2 in touch.
  • sealing lip 17 For sealing the piston-body combination, in particular in the course of a displacement of the piston 3 within the body 2 in the feed direction r, at least one sealing lip 17 is provided. As also shown and preferred, a plurality of mutually spaced sealing lips can be provided over the length of the cylindrical section 16. For example, three sealing lips 17, 18 and 19 are provided, viewed over the axial length of the section 16, wherein the sealing lip 17 is assigned to the front area in the feed direction r, corresponding to the front section 14, and the sealing lip 19 to the end area facing away from the front section 14 of the section 16.
  • the sealing lip 18 extends with respect to the axial direction approximately centrally and at least approximately uniformly spaced in the axial direction between the sealing lips 17 and 19th
  • sealing lips may be in accordance with the embodiments shown in Figures 1 to 11 in a cross section forward, ie in the feed direction r, be swept. This sweep is due to an orientation of the respective points which is acute-angled relative to the longitudinal axis x.
  • Sealing lip wherein the sealing lip 17, 18 or 19 in its direction extending centrally through line a, which is an angle bisecting the feed direction r facing sealing lip surface and the opposite direction of feed r facing sealing lip surface, with the longitudinal axis x an acute angle ⁇ of 30 to 60 °, more preferably 40 to 50 ° includes (see Figure 2).
  • the front portion 14 of the piston 3 protrudes in the feed direction r beyond the foremost sealing lip 17, with a dimension m which is 0.1 to 0.7 times, preferably 0.2 to 0.7 times, more preferably 0.5 times a smallest piston diameter.
  • the smallest piston diameter is given by the diameter d 'approximately with reference to FIGURE 2 or 2a, as is the diameter d "with respect to FIGURE 12.
  • the protrusion is oriented in the embodiment of FIGURES 2 and 2a In an embodiment according to FIG. 12, the protrusion is oriented at the intersection between the dimension auxiliary line relating to the dimension d 'and the front contour edge of the piston.
  • a swept-aligned sealing lip in particular the foremost sealing lip 17, but possibly also, as is also preferred, the average sealing lip 18 considered in the longitudinal extent of the piston 3, as well as according to the first shown in Figures 2 to 6 Embodiment, the rear sealing lip 19, with respect to the feed direction r both above and below the same in each case over into a circular cylindrical portion of the piston 3, which may be formed by the portion 15 or the portion 16.
  • the front sealing lip 17 is in the feed direction r over considered in the diameter-reduced cylindrical portion 15 and the lower side in the corresponding larger diameter portion 16 via.
  • the middle sealing lip 18 can merge on the upper and lower sides into a section 16 of equal diameter design over the axial length (see FIG. 7, the middle sealing lip 18 formed in the step region of the section 16 merges with the section 16 with the diameter d 'and the underside with the enlarged section of the section 16 with the section 16 Diameter d ".
  • the rear, possibly third, sealing lip 19 may be formed as a conventional, strictly radially aligned, sealing lip as shown in Figures 7 and 9.
  • the swept position of the sealing lips results in a circumferential groove 20 between the sealing lip surface pointing in the feed direction r and the associated lateral surface of the section 15 or section 16.
  • a sealing lip protrudes into a cross section, for example according to FIGS. 2 or 7 considered over the largest piston diameter, here piston diameter d 'in Figure 2 or piston diameter d "in Figure 7.
  • all grooves 20 protrude all swept to the front sealing lips beyond the largest piston diameter.
  • a piston outer surface which is extended in the feed direction r, adjoins the section 16 of the piston 3 adjoining the forwardmost sealing lip 17 in the feed direction r, viewed in an extension, which here corresponds to the dimension line d ', the rim
  • the imaginary extension of the piston outer surface accordingly passes through the channel 20 in the feed direction r up to a projecting beyond the foremost sealing lip 17th
  • An immediate transition of the front section 14 into the front sealing lip 17 can also be formed, corresponding to the omission of a cylindrical section 15, cf. approximately Figure 12.
  • the considered in cross-section curvature of the front portion is in this design with a concave curvature directly into the sealing lip 17 on.
  • the transition can be viewed in cross-section at an intersection with a line corresponding to the largest diameter d '.
  • the end face facing away from the front portion 14, in a transverse plane to the longitudinal axis x aligned end face may be formed smooth surface. Also can be formed integrally and uniform material from the piston material out hemispherical elevations 21 on this face. It is possible for a plurality of such elevations, for example five, six to ten, to be arranged on a circular line running concentrically with respect to the longitudinal axis x, with a spacing which is preferably uniform in the circumferential direction (see FIGS. 7 to 11).
  • the piston 3 is preferably produced in the plastic injection molding method, this further preferably in one-piece, preferably of material-uniform design.
  • the complete surface of the piston 3 is given solely by the piston material.
  • the diameter dimension e of the sealing lip 17, which is decisive for the sealing of the piston 3 relative to the inner wall surface of the cylindrical body 2, is somewhat larger in order to ensure the sealing engagement.
  • this sealing lip diameter e may correspond to approximately 1.1 to 1.5 times, further approximately 1.2 times the diameter of the piston section d '.
  • the further sealing lips 18 and 19 may have the same diameter e as the sealing lip 17. These then likewise come into sealing contact with the inner wall surface of the body 2.
  • the further sealing lips 18 and 19 may be reduced in diameter.
  • they can have a diameter e 'substantially equal to the inner diameter of the cylindrical body 2.
  • the sealing lips 18 and 19 with such a diameter e ' take on less sealing tasks, but rather a friction-reduced support of the piston 3 on the Wandungsinnen Chemistry the body 2.
  • This provides in particular a high layer stability of the piston in the cylinder of the body. 2
  • the front in the feed direction r sealing lip 17 may be in accordance with the further embodiment shown in Figure 12 in a cross section to the rear, ie against the feed direction r, be swept.
  • this arrowing results from an alignment of the sealing lip 17 that is acute-angled relative to the longitudinal axis x.
  • a line a passing centrally through the sealing lip 17 in its direction of extension, which is an angle bisector of the sealing lip surface pointing in the feed direction r and the direction opposite to the feed direction r facing sealing lip surface is, with the longitudinal axis x an acute angle ⁇ 'from 45 to 75 °, more preferably includes about 50 to 60 °.
  • the front section 14 of the piston 3 projecting beyond the foremost sealing lip 17 in the advancing direction r is designed in this embodiment as a circular cone, the sealing lip surface of the foremost sealing lip 17 pointing in the advancing direction r in the exemplary embodiment shown at the same time and steplessly in FIG the end face of the front portion 14 enters.
  • the middle and lower sealing lips 18 and 19 are bead-shaped in cross-section in the embodiment, with the middle sealing lip 18 on the upper side, i.
  • the lower sealing lip 19 is bounded on both sides by the larger diameter portion.
  • the diameter e of the foremost sealing lip 17 may be greater than the diameter e 'in the region of the further sealing lips 18 and 19.
  • the sealing lip 17 has a radial projection f, which corresponds to two tenths or more of the diameter d 'of the cylindrical section 16, relative to the cylindrical section 16 immediately opposite the feed direction r.
  • the radial projection f may also correspond to one-sixth or more of the diameter d 'of the cylindrical section 16.
  • the protrusion amount f may correspond to one third of the diameter d 'of the cylindrical portion 16 or more.
  • the supernatant measure can also be given in a range between two tenths and four tenths of the diameter d '.
  • the thickness g of the sealing lip 17 considered in the direction of the longitudinal axis x may be in a central region viewed in the radial direction, in particular on half of the projection f, approximately four tenths or less, up to two tenths or one sixth or less of the diameter d ', possibly even up to, for example, one twentieth of the diameter d' correspond.
  • a fragmentary representation of a piston is reproduced, in cross-section, in which a mold parting line 22, which here shows a punctiform image, is reproduced.
  • this mold parting line 22 is within, i. set back radially inward, given a largest diameter e of the piston 3 in the region of a sealing lip 19.
  • the sealing lip 19 is selected here only as an example for illustration. It may also alternatively or additionally be a sealing lip 17 and / or 18 act.
  • the shape may also have a number of separations over the length of the piston (horizontal, i.e. transverse to the later direction of advance).
  • the illustrated mold parting line can thus lead to a certain, albeit slight, undercut with respect to removal from a mold in the region of a sealing lip 17, 18, 19.
  • a piston which is characterized in that the piston 3 in the plastic injection molding method is made of a fluorine-based plastic material.
  • a piston which is characterized in that the piston 3 in the case of a sweep forward in the feed direction r has a projecting beyond a foremost portion of a frontmost sealing lip 17 front portion 14.
  • a piston which is characterized in that the piston 3 with respect to a sealing lip 17, 18, 19 in the case of a backward sweep has a given over a subsequent in the direction of the arrow cylindrical portion 16 radial projection f, the one Sixth or more of the diameter d 'of the cylindrical portion 16 corresponds.
  • a piston which is characterized in that a thickness g of the supernatant f in the direction of a longitudinal axis x of the piston 3 on one half of the radial projection f corresponds to four tenths or less of the diameter d '.
  • a piston which is characterized in that the thickness g corresponds to one sixth or less, approximately to one tenth or less of the diameter d '.
  • a piston which is characterized in that the piston 3 is made of a fluorine-based material in the plastic injection molding method that the piston 3 counter to the feed direction r below a frontmost sealing lip 17 a largest piston diameter d ', d "forms and that a channel 20 formed by the swept-forward sealing lip 17 with respect to a central region of the piston 3 extends in a cross-section radially beyond the largest piston diameter d ', d ".
  • a piston which is characterized in that in an axial direction of the piston 3 in succession a plurality of sealing lips 17, 18, 19, which have a forward sweep on a given for the application of liquid from the syringe 1 in use feed direction r, are formed.
  • a piston which is characterized in that in an axial direction of the piston 3, a plurality of sealing lips 17, 18, 19 are formed, which has a backward sweep to a given for the application of liquid from the syringe 1 in use Feed direction r have.
  • a piston characterized in that the piston tip is formed by a contour curved in cross-section, wherein the contour line merges with a concave curvature in the frontmost sealing lip 17, wherein the transition in cross-section on or within a largest piston diameter d ', d "is formed.
  • a piston which is characterized in that a mold parting line 22 in the region of a sealing lip 17, 18, 19 is set back radially inwardly with respect to a maximum diameter e of the piston.
  • a piston characterized in that the piston 3 is made in one piece.
  • a medical syringe 1 having a cylindrical body 2 into which a piston 3 is inserted, the piston 3 having one or more of the features described above with respect to the piston as such.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un piston (3) fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale (1), le piston (3) présentant une ou plusieurs lèvres d'étanchéité (17, 18, 19), une lèvre d'étanchéité (17, 18, 19) étant en outre inclinée, en coupe transversale, vers l'avant ou vers l'arrière par rapport à un sens d'avancement (r) donné lors de l'utilisation pour faire sortir du liquide de la seringue (1). Pour améliorer un piston en question, selon l'invention, le piston (3) est fabriqué dans le procédé de moulage par injection de matière synthétique en une matière synthétique à base de fluor. Dans le cas d'une lèvre d'étanchéité (17) inclinée vers l'avant, une rainure (20) peut être réalisée par rapport à une zone centrale du piston, qui, vue en coupe transversale, dépasse radialement au-delà du diamètre (D', D") le plus grand du piston. En outre, l'invention concerne une seringue médicale pourvue d'un piston présentant une des formes de réalisation indiquées.
PCT/EP2017/078154 2016-11-04 2017-11-03 Piston fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale et seringue médicale Ceased WO2018083221A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102016121066.8 2016-11-04
DE102016121066 2016-11-04

Publications (1)

Publication Number Publication Date
WO2018083221A1 true WO2018083221A1 (fr) 2018-05-11

Family

ID=60382175

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/078154 Ceased WO2018083221A1 (fr) 2016-11-04 2017-11-03 Piston fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale et seringue médicale

Country Status (2)

Country Link
DE (1) DE102017125703A1 (fr)
WO (1) WO2018083221A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3586895A1 (fr) * 2018-06-21 2020-01-01 Kabushiki Kaisha Shofu Injecteur
CN115515668A (zh) * 2020-04-24 2022-12-23 费森尤斯卡比德国有限公司 医用注射器以及用于医用注射器的柱塞

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375778A1 (fr) * 1987-06-19 1990-07-04 Terumo Kabushiki Kaisha Instrument medical et production de cet instrument
DE19817548A1 (de) * 1996-10-18 1999-10-21 Schering Ag Spritze mit Spritzenkolben aus Kunststoff
WO2001060434A1 (fr) 2000-02-15 2001-08-23 Disetronic Licensing Ag Bouchon de piston constitue de deux composants
JP2002263187A (ja) * 2001-03-08 2002-09-17 Terumo Corp ガスケットおよびシリンジ
EP0925798B1 (fr) 1997-12-24 2003-05-14 Bracco International B.V. Montage de tige et piston pour seringue ou cartouche avec glissement léger
DE102005003516B3 (de) 2005-01-25 2006-04-13 Smiths Medical Deutschland Gmbh Blutentnahmereservoir
US20070088291A1 (en) * 2005-09-07 2007-04-19 Weilbacher Eugene E Syringe construction
US20120253291A1 (en) * 2011-03-28 2012-10-04 Becton Dickinson And Company Plastic Stopper
EP2817043B1 (fr) 2012-02-22 2016-10-26 Consort Medical PLC Ensemble seringue amélioré

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375778A1 (fr) * 1987-06-19 1990-07-04 Terumo Kabushiki Kaisha Instrument medical et production de cet instrument
DE19817548A1 (de) * 1996-10-18 1999-10-21 Schering Ag Spritze mit Spritzenkolben aus Kunststoff
EP0925798B1 (fr) 1997-12-24 2003-05-14 Bracco International B.V. Montage de tige et piston pour seringue ou cartouche avec glissement léger
WO2001060434A1 (fr) 2000-02-15 2001-08-23 Disetronic Licensing Ag Bouchon de piston constitue de deux composants
JP2002263187A (ja) * 2001-03-08 2002-09-17 Terumo Corp ガスケットおよびシリンジ
DE102005003516B3 (de) 2005-01-25 2006-04-13 Smiths Medical Deutschland Gmbh Blutentnahmereservoir
US20070088291A1 (en) * 2005-09-07 2007-04-19 Weilbacher Eugene E Syringe construction
US20120253291A1 (en) * 2011-03-28 2012-10-04 Becton Dickinson And Company Plastic Stopper
EP2817043B1 (fr) 2012-02-22 2016-10-26 Consort Medical PLC Ensemble seringue amélioré

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3586895A1 (fr) * 2018-06-21 2020-01-01 Kabushiki Kaisha Shofu Injecteur
US11679202B2 (en) 2018-06-21 2023-06-20 Kabushiki Kaisha Shofu Injector capable of suppressing subsequent dripping of fluid
CN115515668A (zh) * 2020-04-24 2022-12-23 费森尤斯卡比德国有限公司 医用注射器以及用于医用注射器的柱塞

Also Published As

Publication number Publication date
DE102017125703A1 (de) 2018-05-09

Similar Documents

Publication Publication Date Title
DE69912380T2 (de) Kolben für Spritzen
DE60017513T2 (de) Spritzenendstückkappe
EP2066374A1 (fr) Ensemble cylindre-piston avec au moins trois éléments d'étanchéité
DE60114740T2 (de) Injektor mit Kraftsensor auf dem Kolben
DE102010035891A1 (de) Spritze für den Gebrauch mit einer Dosiervorrichtung
EP2731647B1 (fr) Seringue multichambre
EP2533908A1 (fr) Dispositif de distribution présentant un élément d'encliquetage
EP0642365A1 (fr) Seringue
EP2412448A2 (fr) Capsule et piston
EP3548122B1 (fr) Piston destiné à une seringue médicale
EP1212984B1 (fr) Seringue pour l'administration dosée de produits dentaires
WO2018083221A1 (fr) Piston fabriqué dans un procédé de moulage par injection de matière synthétique pour une seringue médicale et seringue médicale
EP4138959A1 (fr) Seringue médicale et bouchons de piston pour seringue médicale
EP1180377A1 (fr) Seringue avec piston
EP2522438B1 (fr) Pistons de fermeture et d'impression pour cartouches pour masses plastiques et procédé d'insertion d'un tel piston dans une cartouche
DE10218859B4 (de) Kapsel aus Kunststoff zur Aufbewahrung und Abgabe von Dentalmaterial
WO2014125051A1 (fr) Procédé de fabrication d'une cartouche destinée à recevoir et à délivrer de manière dosable un matériau dentaire coulant et cartouche ainsi fabriquée
EP4072471B1 (fr) Cartouche et injecteur équipé de cette cartouche
DE102013004077A1 (de) Verfahren zum Herstellen einer Kartusche zum Aufnehmen und dosierbaren Abgeben eines fließfähigen Dentalmaterials und eine solche Kartusche
WO2005009517A1 (fr) Seringue medicale pour injection
DE19934235A1 (de) Instrument zum Austragen
EP1989030A1 (fr) Tete de melange anti-fluage pour piston de nettoyage
EP4138962B1 (fr) Bouchon de piston pour une seringue médicale ainsi que seringue médicale dotée d'un bouchon de piston
DE102008058037B4 (de) Kolben und Kolbenspritzenset
DE29806434U1 (de) Spritze für medizinische Zwecke

Legal Events

Date Code Title Description
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17800444

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17800444

Country of ref document: EP

Kind code of ref document: A1