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WO2018074642A1 - Composition cosmétique de protection des lèvres, comprenant des céramides naturels et de l'huile de cynorrhodon en tant que principes actifs - Google Patents

Composition cosmétique de protection des lèvres, comprenant des céramides naturels et de l'huile de cynorrhodon en tant que principes actifs Download PDF

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Publication number
WO2018074642A1
WO2018074642A1 PCT/KR2016/012000 KR2016012000W WO2018074642A1 WO 2018074642 A1 WO2018074642 A1 WO 2018074642A1 KR 2016012000 W KR2016012000 W KR 2016012000W WO 2018074642 A1 WO2018074642 A1 WO 2018074642A1
Authority
WO
WIPO (PCT)
Prior art keywords
cosmetic composition
lip
lips
ceramide
protecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2016/012000
Other languages
English (en)
Korean (ko)
Inventor
김형교
안경화
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genpeau Corp
Original Assignee
Genpeau Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genpeau Corp filed Critical Genpeau Corp
Priority to CN201680037906.8A priority Critical patent/CN108348441A/zh
Publication of WO2018074642A1 publication Critical patent/WO2018074642A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/0229—Sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A61Q1/06—Lipsticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes

Definitions

  • the present invention relates to a cosmetic composition for protecting the lips containing natural ceramide and rose hip fruit.
  • Lips are bordered at the edges of the mouth, developed only in mammals, and appear red because they have many capillaries.
  • the lips are constantly contracting and dilatating, one of the most moving parts of the body, and because there are no pores on the lips, they do not secrete sweat or sebum, so natural moisturizing is not formed.
  • the lips are always exposed to the outside, they are easily irritated by environmental factors such as ultraviolet rays, air pollutants and dry weather. And unlike the general skin structure, the skin structure of the lips has no sebaceous membrane and the stratum corneum is formed very thin, so there is absolutely no natural moisturizing factor and amount of water, and the rate of water evaporation is extremely fast.
  • the lip cosmetics should have a more thorough moisturizing action unlike other cosmetics.
  • the cosmetic composition for lips refers to a cosmetic composition that is beautifully provided by imparting a color effect on the lips and is used for the purpose of protecting the lips.
  • wax of a solid component that first increases the hardness to maintain the appearance form of the cosmetic composition for the lips
  • waxes commonly used are candelillan, ceresin, carnauba wax, and paraffin.
  • Wax, braze, beeswax, microcrystalline lead are used, but if the content of these solid ingredients is high, the hardness of the lip cosmetic composition is high and hard, and the feeling of use is heavy, and the applicability is low. But it clumps easily and gets more smeared, so it doesn't spread evenly on the lips and spreads along the lip line.
  • liquid oil components such as jojoba oil, squalane, lanolin oyl, lanolin derivatives, oils and animals extracted from animals and plants, synthetic ester oils or silicone oils. It acts as a factor that has a big impact on.
  • organic pigments are generally high solubility, and these dyes are rarely used in the cosmetic composition for lips because they may be stained on the lips, but the color of the organic pigments Because it is bright, a dye made of such an insoluble lake may be used.
  • inorganic pigments such as iron oxide may be used.
  • antioxidants such as antioxidants, preservatives, fragrances, and nutritional ingredients may be included, along with potency ingredients, vitamins, high moisturizing ingredients or antioxidant ingredients for improving lip condition.
  • sunscreens and special nutritional ingredients may be formulated to protect your lips from UV rays and to prevent roughening.
  • the first is water or hydrophilic components.
  • water should be particularly careful in the process of volatilization during the process, and if water is simply mixed for the moisturizing effect, water may be volatilized to promote dryness of the lips or shrinkage of the contents. .
  • lanolin, lanolin derivatives, cholesterol derivatives, fatty acid and ester-based compositions including alcohol groups are used for lip protection and moisturizing purposes.
  • allergies have been reported in lanolin and lanolin derivatives, and are currently in limited use.
  • cholesterol derivatives in consideration of the moisturizing effect 5% or more has a disadvantage in that the feeling of use is sticky and heavy.
  • the present inventors have diligently researched to overcome the problems of the prior art, and as a result of using both natural ceramide and rosehip fruit oil having excellent skin barrier protection and moisturizing effects, the effects of moisturizing and wrinkle improvement of the lips have been improved.
  • the present invention was completed by confirming that the product is elevated than when used alone.
  • the present invention provides a cosmetic composition for protecting the lips containing natural ceramide and rose hip fruit.
  • the cosmetic composition is characterized in that to improve the moisturizing and wrinkles of the lips.
  • the natural ceramide may be ceramide 3.
  • the mixed weight ratio of the natural ceramide and rosehip fruit oil is characterized in that 1:10 ⁇ 10: 1.
  • the cosmetic composition may further comprise a pigment.
  • the cosmetic composition is characterized in that it has a formulation selected from the group consisting of lip gloss, lip balm, lip cream and lipstick.
  • the components included in the cosmetic composition of the present invention include components commonly used in cosmetic compositions, in addition to the natural ceramide and rosehip fruit oils described above, and include, for example, conventional antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings. Phosphorus aids, and carriers.
  • Lip cosmetic composition containing the natural ceramide and rosehip fruit oil of the present invention as an active ingredient is a bio-friendly, including a lip skin-like structural material, exhibits excellent lip skin moisturizing and lip skin barrier function recovery when applied to the lips, It has a synergistic effect in promoting moisturizing and elasticity and improving lip wrinkles and has an excellent lip protective effect.
  • the present invention provides a cosmetic composition for protecting the lips containing natural ceramide and rose hip fruit.
  • the outermost surface of human skin consists of keratinocytes that have differentiated from the basal layer and have matured keratinocytes. These keratinocytes are bound by the double-stranded lamellar structure of ceramide, which is present in large quantities in the stratum corneum, thus maintaining a smooth and elastic skin.
  • Ceramide in the cosmetic composition of the present invention is one of the skin structural lipids, which is present in the stratum corneum of the skin epidermal layer and accounts for about 40-50% of the lipid component of keratinocytes.
  • Such ceramide forms a multiple lamellar structure between keratinocytes along with other keratinocyte lipid components, thereby inhibiting evaporation from the skin and maintaining moisture to soften the skin and keep the skin healthy.
  • Ceramide is also responsible for the retention of moisture, which prevents external leakage of moisture other than the skin barrier that prevents the entry of external stimuli.
  • the skin barrier is not complete and the skin becomes rough with the loss of moisture in the body.
  • the natural ceramide according to the present invention may be selected from the group consisting of, for example, ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, ceramide 7, and ceramide 8, and preferably ceramide 3 days.
  • the natural ceramide may provide skin barrier protection, moisture retention, stratum corneum protection, and the like.
  • Rosehip fruit oil contained in the cosmetic composition of the present invention is an oil extracted from the rose seeds of the Chilean Andes is excellent in improving symptoms such as burns, facial wrinkles and tissue regeneration effect is very beneficial for the treatment of scars after surgery.
  • the vitamin content of rose hip fruit is 20 times that of orange and 60 times that of levon. It contains antioxidants that help prevent aging. It also helps collagen synthesis and help tissue cells grow and repair bones, gums and teeth.
  • beta-carotene contained in rose hip fruit is converted to vitamin A in the body as needed to help the cell regeneration and growth through the antioxidant activity of the skin epidermal cells, eyes, digestive and respiratory organs.
  • the beta carotene neutralizes the action of ultraviolet rays and has an internal ultraviolet blocking effect and an anticancer effect.
  • Rosehip fruit is the fruit of the rose family, which grows mainly in Europe and South America. It generally starts to bear fruit in spring and matures in late summer or early autumn. Traditionally, it is known to consume 2-5 grams of powder per day, and its effects have been studied in various ways, especially antioxidant, anti-inflammatory, anti-obesity, anti-diabetic, anti-microbial, and anticancer mutations. Etc. are known.
  • the lips Unlike normal skin, the lips have very thin keratinocyte layers and different lipid components. Especially, the skin lacks a lot of ingredients such as ceramide and free fatty acids that protect skin.
  • the dermis is a connective tissue under the epidermis.
  • the dermis is not filled with cells as closely as the epidermis, but rather has a lot of extracellular space, part of which is filled by the network of macromolecules called extracellular matrix. Over time, the part of the cell that is conjugated to the extracellular matrix becomes weaker and the density of its structure decreases with the total number of cells interacting.
  • the three-dimensional structure of the tissue is also gradually degraded and the ability of the fibroblasts to synthesize and secrete extracellular matrix is also reduced. In other words, the skin loses its elasticity.
  • the lip cosmetic composition of the present invention using a natural ceramide and rose hip fruit oil mixed with the outermost stratum corneum and the dermal layer of the skin for the protection of the lips and effective in maintaining the moisture and skin barrier, gives the lips a moisturizing effect and gradually It is effective in improving lip wrinkles by enhancing elasticity.
  • the cosmetic composition for lip protection of the present invention exhibits the use of lip protection through lip hydration enhancement and lip wrinkle improvement.
  • lip protection means to protect the lips by improving the condition of the lips through enhancing the moisturizing of the lips, suppressing wrinkle formation of the lips and improving the generated wrinkles.
  • the lip cosmetics containing natural ceramide and rosehip fruit oil together have superior lip moisturizing effect, lip roughness improvement and lip wrinkle improvement effect when using each of the above components.
  • the mixed weight ratio of the natural ceramide and rosehip fruit oil is not limited thereto, but may be 1:10 to 10: 1. If it is out of the above range, the synergistic effect in protecting the lips may be insignificant or the feeling of use may be reduced.
  • the cosmetic composition for protecting the lip according to the present invention may have a coloring effect by additionally including a pigment.
  • the pigment may contain 0.1 to 20.0% by weight based on the total weight of the composition, and the pigment is typically a powder or coloring pigment such as silica, white mica, synthetic mica, goodness, kaolin, titanium dioxide, titanium oxide coated mica, or the like. Can be.
  • Ingredients included in the cosmetic composition for lip protection of the present invention as an active ingredient include ingredients commonly used in cosmetic compositions in addition to the active ingredients, for example, conventional auxiliary agents such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings. And carriers.
  • Lip cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, it may be formulated as lip gloss, lip balm, lip cream and lipstick, but is not limited thereto.
  • composition ratio shown in Table 1 was heated to 85 ⁇ 90 °C completely dissolved to prepare a cosmetic composition for protecting the lips.
  • the mixing ratios of ceramide 3 and rose hip fruit oil were compared in the same manner as in Examples 1 to 3 and Comparative Examples 1 to 3.
  • the content unit is weight%.
  • the corneometer was used to quantify the moisture content of the skin from 0 to 150 with the change of electrical conductivity according to the epidermal moisture content, and the Tewameter was used to measure the transdermal loss amount (TEWL), that is, the epidermal water loss.
  • TEWL transdermal loss amount
  • the electrical conductivity of the lips was measured, and the lip cosmetics of Examples 1 to 3 and Comparative Examples 1 to 3 were applied twice a day for 4 weeks, and then after 2 weeks and 4 weeks, The electrical conductivity and TEWL of were measured.
  • the wrinkle improvement effect was analyzed by the average wrinkle roughness (Rz) of Equation 1, which is a value obtained by dividing the sum of roughness (Rm: m is an integer of 1 or more) of each wrinkle by the number of wrinkles.
  • Rz average wrinkle roughness
  • a patch test was performed on 30 adult men and women aged 20 to 55 years. Thirty subjects were sampled using the Van Der Bend chamber between the shoulder blades and the waistline with the spine at the back. The patch was applied to the skin for 48 hours, and after the patch was removed, the test sites were marked with a marking pen. After 30 minutes, 24 hours, and 120 hours, the test sites were observed.
  • the skin response was classified according to the criteria of the International Contact Dermatitis Research Group (ICDRG), and after calculating the mean score according to the formula for calculating the average skin response, the skin patch test result judgment table [Table 4] The presence or absence of irritation was determined according to the above.
  • IDRG International Contact Dermatitis Research Group

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une composition cosmétique de protection des lèvres, disposant d'excellents effets d'hydratation des lèvres et d'atténuation des rides des lèvres grâce à l'utilisation de céramides naturels disposant d'excellents effets de protection et d'hydratation de la barrière cutanée conjointement avec de l'huile de cynorrhodon disposant d'excellents effets d'atténuation des rides et de régénération tissulaire. Selon la présente invention, les céramides naturels et l'huile de cynorrhodon, qui sont les principes actifs de la composition cosmétique de protection des lèvres, disposent d'un effet synergique sur l'hydratation des lèvres et l'atténuation des rides des lèvres, et disposent ainsi d'un excellent effet de protection des lèvres.
PCT/KR2016/012000 2016-10-19 2016-10-25 Composition cosmétique de protection des lèvres, comprenant des céramides naturels et de l'huile de cynorrhodon en tant que principes actifs Ceased WO2018074642A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201680037906.8A CN108348441A (zh) 2016-10-19 2016-10-25 含有天然神经酰胺及玫瑰果油作为有效成分的唇部保护用化妆品组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2016-0136039 2016-10-19
KR1020160136039A KR101794555B1 (ko) 2016-10-19 2016-10-19 천연 세라마이드 및 로즈힙열매 오일을 유효성분으로 함유하는 입술 보호용 화장료 조성물

Publications (1)

Publication Number Publication Date
WO2018074642A1 true WO2018074642A1 (fr) 2018-04-26

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PCT/KR2016/012000 Ceased WO2018074642A1 (fr) 2016-10-19 2016-10-25 Composition cosmétique de protection des lèvres, comprenant des céramides naturels et de l'huile de cynorrhodon en tant que principes actifs

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KR (1) KR101794555B1 (fr)
CN (1) CN108348441A (fr)
WO (1) WO2018074642A1 (fr)

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KR102017619B1 (ko) * 2017-12-08 2019-09-04 스킨큐어 주식회사 항염, 항소양증, 피부보습 및 피부진정용 조성물
KR102248265B1 (ko) * 2018-12-20 2021-05-04 (주)아담네이처 안정성이 우수한 세라마이드 볼의 제조방법 및 상기 제조방법에 의해 제조된 안정성이 우수한 세라마이드 볼
CN109966173A (zh) * 2019-04-25 2019-07-05 傅征澜 一种具有角质层修复功能的口红的制作方法
CN110787088A (zh) * 2019-11-28 2020-02-14 广州那比昂生物科技有限公司 一种淡化唇纹的基础组合物及其制备方法和应用
KR102643173B1 (ko) * 2021-02-17 2024-03-05 코스맥스 주식회사 고함량의 세라마이드 엔피 분산 조성물을 포함하는 스틱 형상 화장료 조성물 및 이의 제조 방법

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Also Published As

Publication number Publication date
KR101794555B1 (ko) 2017-12-01
CN108348441A (zh) 2018-07-31

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