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WO2018059669A1 - Procédé de fonctionnement d'un spectroscope et spectroscope - Google Patents

Procédé de fonctionnement d'un spectroscope et spectroscope Download PDF

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Publication number
WO2018059669A1
WO2018059669A1 PCT/EP2016/072984 EP2016072984W WO2018059669A1 WO 2018059669 A1 WO2018059669 A1 WO 2018059669A1 EP 2016072984 W EP2016072984 W EP 2016072984W WO 2018059669 A1 WO2018059669 A1 WO 2018059669A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
infrared
visible
manipulated
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2016/072984
Other languages
German (de)
English (en)
Inventor
Thomas Engel
Maximilian Fleischer
Alexander Michael Gigler
Remigiusz Pastusiak
Tobias Paust
Elfriede Simon
Evamaria STÜTZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens AG
Siemens Corp
Original Assignee
Siemens AG
Siemens Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens AG, Siemens Corp filed Critical Siemens AG
Priority to PCT/EP2016/072984 priority Critical patent/WO2018059669A1/fr
Publication of WO2018059669A1 publication Critical patent/WO2018059669A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002—Operational features of endoscopes
    • A61B1/00043—Operational features of endoscopes provided with output arrangements
    • A61B1/00045—Display arrangement
    • A61B1/0005—Display arrangement combining images e.g. side-by-side, superimposed or tiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/046—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for infrared imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G01J3/108—Arrangements of light sources specially adapted for spectrometry or colorimetry for measurement in the infrared range

Definitions

  • This invention relates to a method for operating a spectroscope according to the preamble of claim 1 and to a spectroscope according to the preamble of claim 8.
  • 3D endoscopes can be used. These endoscopes allow the situs to be at least partially detected in 3D, e.g. also for documentation purposes.
  • Orifice Transluminal Endoscopic Surgery which can be seen as equal ⁇ synonymous with minimally invasive surgery without scars constitutes a development of laparoscopic minimally invasive surgery.
  • natural orifices are used to avoid visible scars after surgery
  • a challenge that is here is that healthy and not healthy tissue areas not significantly differ in the tissue ⁇ beform and -färbe.
  • spectrometers it is also known to use spectrometers to determine properties of an object under investigation. For example, with a spectrometer in the medical See area by examining tissue parts to make a decision as to whether a tissue sample contains cancerous tissue.
  • optical spectroscopy can be used for this, in which the tissue sample is irradiated with light, in particular in near infrared spectroscopy (NIRS) with short-wave infrared light, and the intensity of the reflected light is then measured as a function of the wavelength of the light.
  • NIRS near infrared spectroscopy
  • All ⁇ recently has not to be the wavelength range from infrared light to visible disadvantage.
  • 3D endoscopy as well as IR spectroscopy are very new technologies for minimally invasive surgery, which are just beginning to be introduced.
  • IR spectroscopy is very new technologies for minimally invasive surgery, which are just beginning to be introduced.
  • the object underlying the invention is to provide a solution which improves the known from the prior art solutions, in particular in which it ensures a further Traumare reduction. This object is achieved by the method of operating a
  • Spectroscope according to the preamble of claim 1 solved by its features and solved by the spectroscope according to the preamble of claim 8 by its features.
  • a releasing at least partly in the visible wavelength range of light light source as a first source for the infrared light used which by the discharged first source of visible light through a first manipulation device manipulated such that the first output of the Mani ⁇ pulations adopted a molded into a beam a fixed infrared wavelength range exhibiting light is emitted, and visible light in the beam path manipulated such that upon impingement of the infrared light on a surface also impacting at least parts of the manipulated light onto the surface to form on the surface a visible first shape which is always in a fixed relationship to one formed by the infrared light on the surface invisible second form stands.
  • the invention has the advantage that infrared radiation is invisible to humans, but bears the decisive material information.
  • imaging the first shape in the specified ratio to the second shape allows the positioning of the IR spot.
  • To support an additional location information both contribute to tissue ⁇ differentiation as well as in support of an operator in the management of the spectroscope, so that a more secure guidance and thus unwanted collisions can be avoided.
  • the first form is generated by a functionally connected to the first Ma ⁇ nipulations owned and operated filter.
  • the process according to the invention is preferably developed in such a way that the filter is visible as light
  • Light spectrum in particular light from the red and / or green spectral range, passing bandpass configured cold light filter is operatively connected to the manipulation device and operated. This is the rule existing cold light filters used and there are still much smaller changes necessary.
  • the method according to the invention is further developed in such a way that the optics operated in the manipulation device are matched to the filter in such a way that a chromatic correction of the dimmed light takes place, a lateral or axial offset which may be created by the manipulation may be minimized.
  • the inventive method also may be further embodied such that the visible light is manipulated such that it is exposed to an intentional chromatic tables aberration such that sharply focused to run through ⁇ a in the beam path is arranged as the last lens, the first mold is finally formabil ⁇ det on the surface.
  • the manipulation without additional Fil ⁇ ter exploited alone by exploiting the already visible visible light components in the beam path of the infrared light and their chromatic aberration and it only needs the existing optics are adjusted accordingly, so that only a small effort is given here.
  • the inventive method is such wei ⁇ ned, and that the manipulation is performed such that the first shape is a circle and / or reflects intersecting lines on the surface.
  • a first source is designed such that for the infrared light, at least partially in the visible wavelength range light emitting light source is used, and so designed such that the visible light emitted by the first source is manipulated by a first manipulation device such that a light shaped to a beam having a predetermined infrared wavelength range is emitted as the first output signal of the manipulation device, and with means such that visible light in the beam ⁇ beam path is manipulated such that meet at such impingement of the inf ⁇ raroten light on a surface and at least parts of the manipulated light on the surface such that they form a visible first form on the surface, which always in a m fixed reference to a formed by the infrared light on the surface pronouncevisba ⁇ Ren second form.
  • the spectroscope according to the invention made possible by the in ⁇ mentation of the realization of the said method for advantages. The same applies to the development of the spectroscope according to the invention, which has means for carrying out the method and one of its further developments.
  • FIG. 1 the sequence of an embodiment of the method according to the invention is shown greatly simplified, On the basis of which also features of the spectroscope and possible embodiments / alternative or supplementary developments of both will be explained in more detail.
  • a transmission of a visible light by a source for example, Ha ⁇ lied light.
  • This step S2 is followed by the generation of the necessary for the IR spectroscopy of infrared light, consistent .
  • filter According to the invention will now be the remaining visible light or - not shown - used an additionally introduced visible light as a marker for the resulting on an object IR spot or is left in a third step S3, the visible light from an intentionally ⁇ erration.
  • This aberration is then compensated according to the invention in a fourth step S4 in such a way that the marker according to the invention produced by the aberration is focused and De ⁇ congruent measuring spot lands on the surface of the object with the IR.
  • both embodiments the typical Si ⁇ situation that underlies halogen sources for IR illumination on are set and is exploited according to the invention that the part of the lamp ⁇ the spectrum can be used in the visible region of the radiation oretisch to move the IR measurement spot.
  • the invention now not working against the occurring in this case, chromatic aberration which prevents that the IR measurement spot and otherwise distorting portions of visible light of the measurement spot by the fact UNNE ⁇ ge visible light in its focus (diameter radially and Po ⁇ sition axial) do not match but even makes use of this or even deliberately provokes it.
  • an additional marker beam optionally implemented as a circle or intersecting lines can be introduced, which gives a Hilfsmarkie ⁇ tion for the surgeon.
  • the filter can, for example, a bandpass filter in the visible spectrum, example ⁇ , in green or red region, and use it for the structure of the pattern to be projected. Furthermore, if the optics for this wavelength are suitably chromatically corrected for the marking, then a lateral or axial offset can be minimized or avoided.
  • the effect is exploited that visible light and IR radiation from different imaging elements are broken differently, that is, there is chromatic aberration.
  • This aberration forces the light spot or, in reverse logic, to set the IR beam appropriately so that the IR spot is sharp again and can deliver an optimal signal.
  • a suitable optic is introduced into the beam path, then the light spot in the visible in front of the last lens of the optic can consciously become one Distortion can be left, so that the chromatic aberration of the last element again results in a perfect superposition of IR radiation and visible portion.
  • the IR spot is then sharply focused, although this is also true for the visible focus.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)

Abstract

L'invention concerne un procédé pour le fonctionnement d'un spectroscope infrarouge, en particulier proche infrarouge, pour une utilisation médicale, en particulier dans la chirurgie invasive minimale, ainsi qu'un spectroscope correspondant dans lequel on utilise, comme première source de lumière infrarouge, une source lumineuse émettant de la lumière au moins partiellement dans la plage de longueurs d'onde visibles. La lumière visible émise par la première source est manipulée par un premier dispositif de manipulation de manière telle qu'une lumière formée en un rayon présentant une plage de longueurs d'onde infrarouges fixe est émise comme premier signal de sortie du dispositif de manipulation et la lumière visible dans le trajet optique est manipulée de manière telle que lorsque la lumière infrarouge rencontre une surface, au moins des parties de la lumière manipulée arrivent également sur la surface de manière telle qu'elles forment, sur la surface, une première forme visible qui est toujours dans un rapport défini avec une deuxième forme non visible représentée par la lumière infrarouge sur la surface.
PCT/EP2016/072984 2016-09-27 2016-09-27 Procédé de fonctionnement d'un spectroscope et spectroscope Ceased WO2018059669A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/072984 WO2018059669A1 (fr) 2016-09-27 2016-09-27 Procédé de fonctionnement d'un spectroscope et spectroscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/072984 WO2018059669A1 (fr) 2016-09-27 2016-09-27 Procédé de fonctionnement d'un spectroscope et spectroscope

Publications (1)

Publication Number Publication Date
WO2018059669A1 true WO2018059669A1 (fr) 2018-04-05

Family

ID=57113292

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2016/072984 Ceased WO2018059669A1 (fr) 2016-09-27 2016-09-27 Procédé de fonctionnement d'un spectroscope et spectroscope

Country Status (1)

Country Link
WO (1) WO2018059669A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013165399A2 (fr) * 2012-05-01 2013-11-07 Empire Technology Development Llc Scanner et projecteur infrarouge indiquant des cellules cancéreuses
WO2015186225A1 (fr) * 2014-06-05 2015-12-10 株式会社ニコン Dispositif de projection du type à balayage, procédé de projection, et système d'assistance chirurgicale
WO2016125165A2 (fr) * 2015-02-05 2016-08-11 Verifood, Ltd. Système de spectrométrie comprenant un faisceau de visée visible

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013165399A2 (fr) * 2012-05-01 2013-11-07 Empire Technology Development Llc Scanner et projecteur infrarouge indiquant des cellules cancéreuses
WO2015186225A1 (fr) * 2014-06-05 2015-12-10 株式会社ニコン Dispositif de projection du type à balayage, procédé de projection, et système d'assistance chirurgicale
WO2016125165A2 (fr) * 2015-02-05 2016-08-11 Verifood, Ltd. Système de spectrométrie comprenant un faisceau de visée visible

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