WO2017221494A1 - Solid preparation printing method and solid preparation printer - Google Patents
Solid preparation printing method and solid preparation printer Download PDFInfo
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- WO2017221494A1 WO2017221494A1 PCT/JP2017/012242 JP2017012242W WO2017221494A1 WO 2017221494 A1 WO2017221494 A1 WO 2017221494A1 JP 2017012242 W JP2017012242 W JP 2017012242W WO 2017221494 A1 WO2017221494 A1 WO 2017221494A1
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- printing
- solid preparation
- solid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
Definitions
- the present invention relates to a solid preparation printing method and a solid preparation printing machine for relieving printing defects such as characters printed on the solid preparation.
- characters, marks, etc. are clearly printed to specify the type of drug and the manufacturer. In addition, an inspection is performed as to whether or not these characters are printed correctly.
- Patent Document 1 describes a configuration in which a print inspection is performed and defective tablets are excluded.
- Patent Document 1 Japanese Patent Laid-Open No. 9-187915
- Patent Document 1 since the one described in Patent Document 1 distinguishes and eliminates printing defects, there is a problem that even though printing defects occur, the medicinal effects are not changed and expensive drugs are wasted.
- This invention solves the said problem and makes it a subject to remedy without wasting even if it is a solid formulation with poor printing.
- the present invention is a solid preparation printing method for printing characters and the like on the surface of a solid preparation, printing characters and the like with a printing device, performing a print inspection with an inspection device, and printing solids
- the present invention provides a solid preparation printing method characterized in that a defective content and a defective portion in a preparation are specified, and correction printing is performed on the defective portion with a correction printing apparatus according to the defective content.
- the correction printing may be performed by superimposing the same color ink as the solid formulation on the misalignment portion, and then the character or the like may be reprinted.
- the present invention is a solid preparation printing machine that prints characters and the like on the surface of a solid preparation, and inspects a printing apparatus that prints characters and the like on the solid preparation, and printed characters and the like Inspection device for identifying defective content and defective part in solid preparation of defective printing, modified printing device for performing correction printing according to the defective content for the defective part, the printing device, the inspection device, and the correction
- the present invention provides a solid preparation printing machine comprising a control device for controlling a printing device.
- the control device may control the correction printing device so as to perform the correction printing for replenishing ink to the missing portion with respect to a solid preparation whose defect content is a lack of characters or the like.
- the modified printing apparatus is configured to be able to select printing with ink of the same color as that of the solid preparation in addition to printing with ink of color such as letters, and the control apparatus is capable of selecting a solid preparation in which the defective content is bleeding such as letters.
- the correction printing apparatus may be controlled so as to perform the correction printing in which the same color ink as the solid preparation is superimposed on the bleeding portion.
- the modified printing apparatus is configured to be able to select printing with ink of the same color as the solid preparation in addition to printing with ink of color such as letters, and the control apparatus is capable of selecting a solid preparation in which the defective content is a deviation of characters or the like.
- the modified printing apparatus is controlled so that the same color ink as the solid preparation is superimposed on the misaligned portion, and the reprint sorting apparatus is controlled to store the solid preparation in the reprinting storage box. Good.
- Example 1 of this invention It is a figure explaining the structure of the solid formulation printing machine in Example 1 of this invention. It is a figure explaining the printing apparatus part of the solid formulation printing machine in Example 1 of this invention. It is a figure explaining the example of the printing defect defect in Example 1 of this invention. It is a figure explaining the example of the printing bleeding defect in Example 2 of this invention. It is a figure explaining the example of the printing misalignment defect in Example 3 of this invention.
- FIG. 1 is a diagram illustrating the configuration of a solid preparation printing machine according to Embodiment 1 of the present invention.
- FIG. 2 is a diagram illustrating a printing device portion of the solid preparation printing machine according to the first embodiment of the present invention.
- FIG. 3 is a diagram for explaining an example of printing defect in the first embodiment of the present invention.
- the solid preparation printer 100 includes a disk 11, a disk 12, a disk 13, a parts feeder 14, a solid preparation input unit 15, a printing device 21, a printing device 31, and an imaging device. 41, an imaging device 51, a correction printing device 61, a correction printing device 71, a reprint sorting device 16, a storage box 17, a reprinting storage box 18, and the like.
- the disk 11 is provided with the main surface vertical
- the disk 12 is provided vertically so as to be orthogonal to the disk 11 and the side surfaces are close to each other
- the disk 13 is horizontal so as to be orthogonal to the disk 12 and the side surfaces are close to each other. Is provided.
- the disk 11, the disk 12, and the disk 13 include a plurality of adsorption holes on the side surface circumference, and the solid preparation T can be adsorbed and held in the adsorption holes.
- the solid preparation T is supplied to the parts feeder 14 from the solid preparation input unit 15.
- the solid preparation T thrown into the parts feeder 14 is gradually aligned in the horizontal direction by the vibration or rotation of the parts feeder 14.
- the aligned solid preparations T are adsorbed on the side surfaces of the plurality of adsorbing holes provided on the circumference of the side surface of the disk 13 at the final end of the parts feeder 14.
- the solid preparation T adsorbed and held in the adsorption holes on the side circumference of the disk 13 is horizontally rotated so as to approach the disk 12 as the disk 13 rotates counterclockwise.
- the solid preparation T that has moved close to the disk 12 starts to be adsorbed to the adjacent adsorption holes in the disk 12, and the adsorption of the adsorption holes of the disk 13 is released, so that the first surface of the solid preparation T is Adsorb to adsorption holes.
- the disk 12 rotates in the vertical direction so that the solid preparation T adsorbed and held approaches the disk 11 by rotating clockwise.
- the solid preparation T that has moved close to the disk 11 starts to be adsorbed to the adsorbing holes adjacent to the disk 11, and the adsorption of the adsorbing holes on the disk 12 is released so that the side surface of the solid preparation T is Adsorption is held in the adsorption hole.
- the solid preparation T adsorbed and held on the disk 11 is vertically rotated in the counterclockwise direction as the disk 11 rotates.
- the disk 11 is received by adsorbing the side surface of the solid preparation T in an upright position from the disk 12, and adsorbs and holds the solid preparation T in an upright position.
- the disk 11 rotates counterclockwise
- the solid preparation T adsorbed and held is rotated and moved counterclockwise.
- the solid preparation T is detected by a sensor (not shown), and the printing device 21 prints characters or the like on the first surface of the solid preparation T.
- characters or the like are printed on the second surface of the solid preparation T by the printing device 31.
- Both the printing device 21 and the printing device 31 are constituted by an inkjet printer, and the solid preparation T that is rotating and moving is ejected from a plurality of nozzles arranged in a line in a direction substantially orthogonal to the rotation direction of the disk 11.
- a predetermined character or the like can be printed on the screen. Characters and the like are stored in advance in a print data storage device (not shown), and a control device (not shown) appropriately instructs print data such as predetermined characters to control the printing device 21 and the printing device 31.
- the nozzle rows in the printing device 21 and the printing device 31 are not limited to one row, and may have a plurality of nozzle rows.
- the printing device 21 and the printing device 31 are not limited to the ink jet printer, and may be a laser printer, a tampo printing device, or a screen printing device.
- the printed solid preparation T is further rotated by the disk 11 further rotating counterclockwise.
- the solid preparation T is detected by a sensor (not shown), and the image pickup apparatus 41 moves the first surface of the solid preparation T being rotated.
- the imaging device 51 images the second surface of the solid preparation T that is rotating and moving.
- the imaging device 41 and the imaging device 51 are both configured by CMOS sensors, and use an electronic shutter and a strobe to take an image so as not to shake the solid preparation T that is rotating and moving.
- the images picked up by the image pickup device 41 and the image pickup device 51 are sent to an inspection device (not shown) to inspect characters printed on each surface.
- the inspection apparatus receives the print data used for printing the characters of the solid preparation T from the control device, and compares the print data used for printing the solid preparation T with the print characters. To inspect. And an inspection apparatus specifies the defect content and defect location of the solid formulation T judged to be a printing defect.
- the print data used for printing the solid preparation T and the captured image such as the printed characters are overlapped and compared to determine whether there is any defect such as chipping, bleeding, or misalignment. That is, when there is a lack of printing in a part of the print character or the like, the content of the print defect is determined as a lack defect and a defective part is specified. In addition, when there is an extra print location in a portion other than the print data, the print failure is determined to be a bleeding failure and the bleeding failure location is specified. Further, when the position where the print character or the like should be printed is greatly deviated, it is determined that the print defect is a misalignment and the misalignment location is specified. In addition, when there are a plurality of defect contents, the defect contents and the defect locations for all the existing defect contents are specified.
- FIG. 3A shows print data.
- the inspection apparatus calculates the difference image by superimposing the captured image such as the print character and the image of the print data.
- FIG. 3C shows an example of the difference image. If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image.
- the number of pixels in the area displayed in black is counted, and if it is equal to or greater than a preset threshold value, it is determined as defective. If the black display portion equal to or greater than this threshold is within the area of the character to be printed, the defective content is determined to be defective.
- a black display area having the number of defective pixels, that is, the number of pixels equal to or greater than a threshold value is specified as a defective portion. However, an area composed of the number of pixels that are black but less than the threshold value is changed to white display. This is to prevent the inspection from becoming too strict. And the image which shows the defective part of the said black display area is memorize
- the solid preparation T is rotated and moved to a position where the correction printing device 61 and the correction printing device 71 can print. However, the solid preparation T that has not been determined to be defective is further rotated without correction printing. And stored in the storage box 17.
- the solid preparation T determined to be defective in printing is subjected to correction printing by the correction printing device 61 and the correction printing device 71. That is, when the solid preparation T is rotated and moved to a position where the correction printing apparatus 61 and the correction printing apparatus 71 can print, the solid preparation T is detected by a sensor (not shown), and the solid preparation T is determined to be defective in printing. If so, the correction printing device 61 performs correction printing on the first surface of the solid preparation T being rotated, and the correction printing device 71 performs correction printing on the second surface of the solid preparation T being rotated. Both the correction printing device 61 and the correction printing device 71 are constituted by an ink jet printer that can eject two different colors. Specifically, the modified printing device 61 and the modified printing device 71 are each configured by two inkjet printers, and are configured to be capable of selectively ejecting two types of ink, such as characters and the same color as the solid preparation T, respectively.
- Example 1 when the defective solid preparation T is rotated and transported, ink of a color or the like is ejected onto the solid preparation T only in the black display area of the defective portion image stored in the control device. Then refill the missing part with ink. As a result, ink is replenished to the chipped portion of the solid preparation T, the chipping disappears, and the solid preparation T can be relieved.
- the rescued solid preparation T is stored in the storage box 17 in the same manner as the solid preparation T that was not determined to be defective in printing.
- Example 1 the devices are arranged in the rotational movement direction of the solid preparation T, such as the printing device 21 and the printing device 31, the imaging device 41 and the imaging device 51, the modified printing device 61, and the modified printing device 71.
- the solid preparation T that has become defective in printing is remedied.
- the present invention is not necessarily limited to this, and can be appropriately changed depending on the convenience of the solid preparation printing machine.
- the printing apparatus 21, the printing apparatus 31, the imaging apparatus 41, and the imaging apparatus 51 are provided, and after the defective solid preparation T is discharged, the solid preparation printing machine 100 is loaded again, and the printing apparatus 21
- the printing apparatus 31 may be positioned as a correction printing apparatus so as to perform correction printing.
- Example 1 the printing device 21 and the printing device 31 print characters or the like on both surfaces of the solid preparation T, and the imaging device 41 and the imaging device 51 capture both surfaces of the solid formulation T to perform a print inspection.
- the present invention is not limited to this, and can be appropriately changed depending on the convenience of the solid preparation printing machine.
- it may be configured such that characters or the like are printed on only one of the surfaces, and the printed inspection is performed only on the printed surface, so that correction printing is performed.
- inspection may be carried out by imaging the side surface of the solid preparation T in which the 1st surface is adsorbed by the disk 12 with an imaging device.
- Example 1 since the solid preparation T adsorbed and held with the rotation of the disk 11 does not shift with respect to the disk T, the black portion of the defective portion image stored in the control device is displayed in the black display area. Based on this, the correction printing device 61 and the correction printing device 71 are configured to perform correction printing by discharging ink. Further, when the solid preparation T is transported by a drum or a magazine, the position is hardly shifted, so that correction printing can be performed with the same configuration. However, since the position may be shifted when the solid preparation T is conveyed by the conveyor, the position of the solid preparation T is recognized before the correction printing, and the position of the solid preparation T or the defective portion image is corrected. You may comprise so that correction printing may be performed.
- the first embodiment of the present invention is a solid preparation printing method for printing characters or the like on the surface of a solid preparation, printing characters or the like with a printing apparatus, performing print inspection with an inspection apparatus and printing.
- a defective solid preparation is identified by a solid preparation printing method, wherein a defective content and a defective portion in a defective solid preparation are identified, and correction printing is performed on the defective portion with the correction printing apparatus according to the defective content. Even so, it can be remedied without wasting it.
- a solid preparation printing machine that prints characters on the surface of a solid preparation, a printing device that prints letters etc. on the solid preparation, and inspection of the printed characters etc.
- An inspection device that identifies the defective portion, a correction printing device that performs correction printing according to the content of the defect, and a control device that controls the printing device, the inspection device, and the correction printing device.
- FIG. 4 is a diagram for explaining an example of a print blur defect in the second embodiment of the present invention.
- FIG. 4A shows print data
- FIG. 4B shows an example of a picked-up image with poor bleeding
- FIG. 4C shows an example of a difference image between the print data and a defective blot image.
- the disk 11 receives the side surface of the solid preparation T in the upright posture from the disk 12 and adsorbs and holds the solid preparation T in the upright posture.
- the disk 11 rotates counterclockwise
- the solid preparation T adsorbed and held is rotated and moved counterclockwise.
- the solid preparation T is detected by a sensor (not shown), and the printing apparatus 21 causes the first surface of the solid preparation T being rotated to move.
- Characters and the like are printed, and the characters and the like are printed on the second surface of the solid preparation T that is being rotationally moved by the printing device 31.
- Both the printing device 21 and the printing device 31 are constituted by an ink jet printer, and by discharging ink from a plurality of nozzles arranged in a line in a direction substantially orthogonal to the rotation direction of the disk 11, a predetermined character or the like is formed into a solid preparation.
- Characters and the like are stored in advance in a print data storage device (not shown), and a control device (not shown) appropriately instructs print data such as predetermined characters to control the printing device 21 and the printing device 31.
- the printed solid preparation T is continuously rotated as the disk 11 further rotates counterclockwise.
- the solid preparation T is detected by a sensor (not shown), and the image pickup apparatus 41 moves the first surface of the solid preparation T being rotated.
- the imaging device 51 images the second surface of the solid preparation T that is rotating and moving.
- the imaging device 41 and the imaging device 51 are both configured by CMOS sensors, and use an electronic shutter and a strobe to take an image so as not to shake the solid preparation T that is rotating and moving.
- the images picked up by the image pickup device 41 and the image pickup device 51 are sent to an inspection device (not shown) to inspect characters printed on each surface.
- the inspection apparatus receives the print data used for printing the characters of the solid preparation T from the control device, and compares the print data used for printing the solid preparation T with the print characters. To inspect. And an inspection apparatus specifies the defect content and defect location of the solid formulation T judged to be a printing defect. In addition, the rotational movement is continued without doing anything for the solid preparation T that has not been determined to be defective in printing.
- the print data used for printing the solid preparation T is compared with the print characters and the like, and it is determined whether there is any defect such as chipping, bleeding or displacement.
- the inspection apparatus overlaps the captured image such as the print character and the image of the print data and calculates a difference image (see FIG. 4C). If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image.
- the number of pixels in the area displayed in black is counted, and if it is equal to or greater than a preset threshold value, it is determined as defective. If the black display portion equal to or greater than this threshold is outside the area of the printed character or the like, the defective content is determined to be blurred. In addition, a portion where the bleeding is defective, that is, a black display region having the number of pixels equal to or greater than the threshold is specified as a defective portion. However, an area composed of the number of pixels that are black but less than the threshold value is changed to white display. This is to ensure that the inspection is not too strict. And the image which shows the defective part of the said black display area is memorize
- the solid preparation T is rotationally moved to a position where the correction printing device 61 and the correction printing device 71 can print. If the solid preparation T is rotated and moved to a position where the correction printing apparatus 61 and the correction printing apparatus 71 can print, the solid preparation T is detected by a sensor (not shown), and the solid preparation T is determined to be defective in printing.
- the correction printing device 61 performs correction printing on the first surface of the solid preparation T being rotated
- the correction printing device 71 performs correction printing on the second surface of the solid preparation T being rotated.
- Both the correction printing device 61 and the correction printing device 71 are constituted by an ink jet printer that can eject two different colors.
- the modified printing device 61 and the modified printing device 71 are each configured by two inkjet printers, and are configured to be capable of selectively ejecting two types of ink, such as characters and the same color as the solid preparation T, respectively.
- the solid preparation T with poor bleeding When the solid preparation T with poor bleeding is rotated and moved, the same color ink as that of the solid preparation T is ejected only in the black display area of the above-described defective portion image, and the ink is superimposed on the bleeding portion for correction printing. Controlled by the control device. Thereby, the bleeding part in the said solid formulation T becomes the same as the color of the solid formulation T, a blur disappears, and the said solid formulation T which was a printing defect can be relieved.
- the rescued solid preparation T is controlled by the control device so that the solid preparation T is stored in the storage box 17 in the same manner as the solid preparation T that has not been determined to be defective in printing.
- both the defect content and the defect location are specified. Then, the corrected printing device 61 and the corrected printing device 71 are controlled so that ink of the same color as the solid preparation T is ejected to the bleeding defect portion, and ink of characters or the like is ejected to the missing portion. Thereby, the bleeding defect and the chipping defect are relieved.
- Example 2 the defective content is specified as a bleeding defect and the defective portion is specified, and correction printing is performed by overlaying the same color ink as the solid preparation T on the bleeding portion, thereby blurring characters and the like. Even a printed solid preparation can be saved without being wasted. Also, stains that do not affect the quality can be remedied by performing the same correction printing.
- the third embodiment of the present invention is different from the first and second embodiments in that the print defect content is misalignment.
- Example 3 will be described with reference to FIG.
- FIG. 5 is a diagram for explaining an example of misalignment in the third embodiment of the present invention.
- FIG. 5A shows print data
- FIG. 5B shows an example of a captured image with poor displacement
- FIG. 5C shows a difference image between the print data and the defective displacement image. Since this misalignment defect is a defect content in which the printed characters and the like are largely deviated from the positions to be originally printed, once the ink of the same color as the solid preparation T is corrected and printed on the misaligned portion and discharged, the solid preparation again Relief by putting it in the printing press and reprinting.
- the disk 11 receives the side surface of the solid preparation T in the upright posture from the disk 12 and adsorbs and holds the solid preparation T in the upright posture.
- the disk 11 rotates counterclockwise, the solid preparation T adsorbed and held is rotated and moved counterclockwise.
- the solid preparation T is rotated to a position where the printing apparatus 21 and the printing apparatus 31 can print, the solid preparation T is detected by a sensor (not shown), and characters or the like are formed on the first surface of the rotating solid preparation T by the printing apparatus 21. Are printed on the second surface of the rotating solid preparation T by the printing device 31.
- Both the printing device 21 and the printing device 31 are constituted by an ink jet printer, and by discharging ink from a plurality of nozzles arranged in a line in a direction substantially orthogonal to the rotation direction of the disk 11, a predetermined character or the like is formed into a solid preparation. Can be printed on T. Characters and the like are stored in advance in a print data storage device (not shown), and a control device (not shown) appropriately instructs print data such as predetermined characters to control the printing device 21 and the printing device 31.
- the printed solid preparation T is continuously rotated as the disk 11 further rotates counterclockwise.
- the solid preparation T is detected by a sensor (not shown), and the image pickup apparatus 41 picks up the first surface of the rotating solid preparation T.
- the imaging device 51 images the second surface of the rotating solid preparation T.
- the imaging device 41 and the imaging device 51 are both configured by CMOS sensors, and take an image using an electronic shutter and a strobe so as not to blur.
- the images picked up by the image pickup device 41 and the image pickup device 51 are sent to an inspection device (not shown) to inspect characters printed on each surface.
- the inspection device receives the print data used for printing the character of the solid preparation T from the control device, and compares the print data used for printing the solid preparation T with the print character, etc. Perform an inspection. And an inspection apparatus specifies the defect content and defect location of the solid formulation T judged to be a printing defect. For the solid preparation T that has not been determined to be poor printing, the rotational movement is continued without doing anything here.
- the print data used for printing the solid preparation T and the captured image such as the printed characters are overlapped and compared to determine whether there is any defect such as chipping, bleeding, or misalignment.
- the inspection apparatus calculates a difference image by superimposing the captured image such as the print character and the image of the print data and comparing them (see FIG. 5C). If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image.
- the number of pixels in the area displayed in black is counted, and if it is an area having a preset threshold value or more, it is determined as defective. If the black display area above the threshold is outside the area of the character to be printed and the size of the black display area approximates the size of the character to be printed, the defective content is misaligned. Judge. In addition, the black display area having the number of pixels that is equal to or larger than the threshold is specified as the defective portion. However, the area that is black but is less than the threshold is changed to white. This is to ensure that the inspection is not too strict. And the image which shows the defective part of the said black display area is memorize
- the solid preparation T is rotationally moved to a position where the correction printing device 61 and the correction printing device 71 can print.
- the correction printing device is detected if the solid preparation T is detected by a sensor (not shown) and determined to be defective.
- correction printing is performed on the first surface of the rotating solid preparation T
- correction printing is performed on the second surface of the rotating solid preparation T by the correction printing apparatus 71.
- Both the correction printing device 61 and the correction printing device 71 are composed of two ink jet printers that can eject two different colors. Specifically, it is configured such that two types of ink of the same color of the character and the like and the same color of the solid preparation T can be selectively ejected.
- the misaligned solid preparation T When the misaligned solid preparation T is rotated and moved, the ink of the same color as that of the solid preparation T is ejected onto the solid preparation T based on the above-described defective portion image, and the ink is superimposed on the misaligned portion for correction printing.
- This can be performed by the control device controlling so that ink is ejected only to the black display portion of the defective portion image stored in the control device described above.
- the misaligned portion becomes the same as the color of the solid preparation T, so there is no misalignment, and the solid preparation T is relieved. That is, it is possible to return to the same initial state that is not printed.
- the control device controls the reprint sorting device 16 to store the solid formulation T that has returned to the initial state in the reprint storage box 18.
- the solid preparation T stored in the reprinting storage box 16 is input again into the solid preparation printing machine 100 at an arbitrary timing, and printing, inspection, and correction printing are performed as necessary. In FIG. 2, the description of the reprint sorting device 16 is omitted.
- Example 3 the solid preparation T with poor displacement is ejected with ink of the same color as the solid preparation T and overlaid on the misaligned portion for correction printing, and then stored in the reprint storage box 18. In this case, it is again put in the solid preparation printing machine 100 to perform printing, inspection, and correction printing as necessary.
- the present invention is not necessarily limited to this, and can be appropriately changed depending on the convenience of the solid preparation printing machine. .
- another printing device may be disposed downstream of the corrected printing device 61 and the corrected printing device 71 in the rotational direction of the solid preparation to print characters or the like on the relieved solid preparation T.
- the correction printing device 61 and the correction printing device 71 are controlled so that ink of the same color as the solid preparation T is discharged to the misalignment defective portion and the poor bleeding portion, and ink of a color such as a character is discharged to the missing portion. .
- misalignment, bleeding failure, and chipping failure are remedied.
- Example 3 the defect content is specified as misalignment, the defect location is identified, and after the correction printing is performed by overlaying the same color ink as that of the solid preparation T on the misalignment portion, characters, etc. Can be relieved even if it is a solid preparation T printed with characters or the like shifted.
- the solid preparation printing method and the solid preparation printing machine in the present invention can be widely applied to the field of relieving printing defects such as printed characters.
- Solid formulation input unit 16 Reprint sorting device 17: Storage box 18: Reprint storage box 21: Printing device 31: Printing device 41: Imaging device 51: Imaging device 61: correction printing device 71: correction printing device T: solid preparation
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Abstract
Description
本発明は、固形製剤に印刷された文字等の印刷不良を救済する固形製剤印刷方法及び固形製剤印刷機に関するものである。 The present invention relates to a solid preparation printing method and a solid preparation printing machine for relieving printing defects such as characters printed on the solid preparation.
錠剤やカプセル剤等の固形製剤には、薬の種類や製造者を明示する文字やマーク等(本明細書においては、「文字等」と定義する。)が印刷される。また、この文字等が正しく印刷されているか否かについて検査が行われている。 In solid preparations such as tablets and capsules, characters, marks, etc. (defined as “characters” in this specification) are clearly printed to specify the type of drug and the manufacturer. In addition, an inspection is performed as to whether or not these characters are printed correctly.
特許文献1には、印刷検査を行ない、不良となった錠剤を排除する構成が記載されている。 Patent Document 1 describes a configuration in which a print inspection is performed and defective tablets are excluded.
特許文献1:特開平9-187915号公報 Patent Document 1: Japanese Patent Laid-Open No. 9-187915
しかしながら、特許文献1に記載のものは、印刷不良を区別して排除するものであるため、印刷不良になったとはいえ、薬効に変わりはなく高価な薬剤を無駄にしてしまうという問題があった。 However, since the one described in Patent Document 1 distinguishes and eliminates printing defects, there is a problem that even though printing defects occur, the medicinal effects are not changed and expensive drugs are wasted.
本発明は、上記問題点を解決して、印刷不良の固形製剤であっても無駄にしないで救済することを課題とする。 This invention solves the said problem and makes it a subject to remedy without wasting even if it is a solid formulation with poor printing.
上記課題を解決するために本発明は、固形製剤の表面に文字等を印刷する固形製剤印刷方法であって、印刷装置で文字等を印刷し、検査装置で印刷検査を行なうとともに印刷不良の固形製剤における不良内容と不良個所を特定し、修正印刷装置で当該不良個所に対して前記不良内容に応じた修正印刷を行うことを特徴とする固形製剤印刷方法を提供するものである。 In order to solve the above problems, the present invention is a solid preparation printing method for printing characters and the like on the surface of a solid preparation, printing characters and the like with a printing device, performing a print inspection with an inspection device, and printing solids The present invention provides a solid preparation printing method characterized in that a defective content and a defective portion in a preparation are specified, and correction printing is performed on the defective portion with a correction printing apparatus according to the defective content.
この構成により、印刷不良の固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a poorly printed solid preparation can be remedied without being wasted.
前記不良内容が文字等の欠けである固形製剤に対して、当該欠け部分にインクを補充する前記修正印刷を行うようにしてもよい。 You may make it perform the said correction printing which replenishes the said lacking part with the ink with respect to the solid formulation whose defect content is lacking, such as a character.
この構成により、文字等が欠けて印刷された固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a solid preparation printed with lacking characters or the like can be remedied without being wasted.
前記不良内容が文字等の滲みである固形製剤に対して、当該滲み部分に当該固形製剤と同色のインクを重ねる前記修正印刷を行うようにしてもよい。 You may make it perform the said correction printing which superimposes the ink of the same color as the said solid preparation on the said bleeding part with respect to the solid preparation whose defect content is a blur of characters etc.
この構成により、文字等が滲んで印刷された固形製剤であっても無駄にしないで救済することができる。また、品質に影響のない汚れについても救済することができる。 With this configuration, even a solid preparation printed with characters or the like blurred can be remedied without being wasted. In addition, dirt that does not affect the quality can be relieved.
前記不良内容が文字等のずれである固形製剤に対して、当該ずれ部分に固形製剤と同色のインクを重ねて前記修正印刷を行った後、文字等を再印刷するようにしてもよい。 For the solid preparation in which the defective content is misalignment of characters, etc., the correction printing may be performed by superimposing the same color ink as the solid formulation on the misalignment portion, and then the character or the like may be reprinted.
この構成により、文字等がずれて印刷された固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a solid preparation printed with characters or the like shifted can be relieved without being wasted.
また、上記課題を解決するために本発明は、固形製剤の表面に文字等を印刷する固形製剤印刷機であって、固形製剤に文字等を印刷する印刷装置と、印刷文字等を検査するとともに印刷不良の固形製剤における不良内容と不良個所を特定する検査装置と、当該不良個所に対して前記不良内容に応じた修正印刷を行う修正印刷装置と、前記印刷装置、前記検査装置、及び前記修正印刷装置を制御する制御装置とを備えたことを特徴とする固形製剤印刷機を提供するものである。 Further, in order to solve the above-mentioned problems, the present invention is a solid preparation printing machine that prints characters and the like on the surface of a solid preparation, and inspects a printing apparatus that prints characters and the like on the solid preparation, and printed characters and the like Inspection device for identifying defective content and defective part in solid preparation of defective printing, modified printing device for performing correction printing according to the defective content for the defective part, the printing device, the inspection device, and the correction The present invention provides a solid preparation printing machine comprising a control device for controlling a printing device.
この構成により、印刷不良の固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a poorly printed solid preparation can be remedied without being wasted.
前記制御装置は、前記不良内容が文字等の欠けである固形製剤に対して、当該欠け部分にインクを補充する前記修正印刷を行うように前記修正印刷装置を制御するものであってもよい。 The control device may control the correction printing device so as to perform the correction printing for replenishing ink to the missing portion with respect to a solid preparation whose defect content is a lack of characters or the like.
この構成により、文字等が欠けて印刷された固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a solid preparation printed with lacking characters or the like can be remedied without being wasted.
前記修正印刷装置は、文字等の色のインクによる印刷に加えて固形製剤と同色のインクによる印刷も選択可能に構成され、前記制御装置は、前記不良内容が文字等の滲みである固形製剤に対して当該滲み部分に固形製剤と同色のインクを重ねる前記修正印刷を行うように前記修正印刷装置を制御するものであってもよい。 The modified printing apparatus is configured to be able to select printing with ink of the same color as that of the solid preparation in addition to printing with ink of color such as letters, and the control apparatus is capable of selecting a solid preparation in which the defective content is bleeding such as letters. On the other hand, the correction printing apparatus may be controlled so as to perform the correction printing in which the same color ink as the solid preparation is superimposed on the bleeding portion.
この構成により、文字等が滲んで印刷された固形製剤であっても無駄にしないで救済することができる。また、品質に影響のない汚れについても救済することができる。 With this configuration, even a solid preparation printed with characters or the like blurred can be remedied without being wasted. In addition, dirt that does not affect the quality can be relieved.
前記修正印刷装置は、文字等の色のインクによる印刷に加えて固形製剤と同色のインクによる印刷も選択可能に構成され、前記制御装置は、前記不良内容が文字等のずれである固形製剤に対して当該ずれ部分に固形製剤と同色のインクを重ねるように前記修正印刷装置を制御するとともに、再印刷選別装置を制御して当該固形製剤を再印刷用収納箱に収納するものであってもよい。 The modified printing apparatus is configured to be able to select printing with ink of the same color as the solid preparation in addition to printing with ink of color such as letters, and the control apparatus is capable of selecting a solid preparation in which the defective content is a deviation of characters or the like. On the other hand, the modified printing apparatus is controlled so that the same color ink as the solid preparation is superimposed on the misaligned portion, and the reprint sorting apparatus is controlled to store the solid preparation in the reprinting storage box. Good.
この構成により、文字等がずれて印刷された固形製剤であっても無駄にしないで救済することができる。 With this configuration, even a solid preparation printed with characters or the like shifted can be relieved without being wasted.
以下、図1~図3を参照しながら、本発明の実施例1について説明する。図1は、本発明の実施例1における固形製剤印刷機の構成を説明する図である。図2は、本発明の実施例1における固形製剤印刷機の印刷装置部分を説明する図である。図3は、本発明の実施例1における印刷欠け不良の例を説明する図である。 The first embodiment of the present invention will be described below with reference to FIGS. FIG. 1 is a diagram illustrating the configuration of a solid preparation printing machine according to Embodiment 1 of the present invention. FIG. 2 is a diagram illustrating a printing device portion of the solid preparation printing machine according to the first embodiment of the present invention. FIG. 3 is a diagram for explaining an example of printing defect in the first embodiment of the present invention.
本発明の実施例1における固形製剤印刷機100は、図1に示すように、ディスク11、ディスク12、ディスク13、パーツフィーダ14、固形製剤投入部15、印刷装置21、印刷装置31、撮像装置41、撮像装置51、修正印刷装置61、修正印刷装置71、再印刷選別装置16、収納箱17、再印刷用収納箱18等からなっている。ディスク11は、主面を垂直にして設けられ、ディスク12は、ディスク11と直交かつ側面同士が近接するように垂直に設けられ、ディスク13はディスク12と直交かつ側面同士が近接するように水平に設けられている。ディスク11、ディスク12、ディスク13は、側面円周上に複数の吸着孔を備え、この吸着孔に固形製剤Tを吸着保持することができる。
As shown in FIG. 1, the
次に、固形製剤印刷機100の動作について説明する。まず、固形製剤投入部15から固形製剤Tがパーツフィーダ14に投入される。パーツフィーダ14に投入された固形製剤Tは、パーツフィーダ14の振動又は回転によって次第に水平方向に整列させられる。整列させられた固形製剤Tはパーツフィーダ14の最終端において、ディスク13の側面円周上に設けられた複数の吸着孔のうち近接の吸着孔にその側面を吸着される。ディスク13の側面円周上の吸着孔に吸着保持された固形製剤Tはディスク13の反時計方向への回転に伴って、ディスク12に近づくように水平回転移動させられる。そして、ディスク12に近接移動した固形製剤Tは、ディスク12における近接の吸着孔への吸着を開始するとともに、ディスク13の当該吸着孔の吸着を解除して、固形製剤Tの第1面を当該吸着孔に吸着させる。ディスク12は、時計方向に回転することにより、吸着保持した固形製剤Tをディスク11に近接するように垂直回転する。そして、ディスク11に近接移動した固形製剤Tは、ディスク11における近接の吸着孔への吸着を開始するとともに、ディスク12における当該吸着孔の吸着を解除して、固形製剤Tの側面をディスク11の当該吸着孔に吸着保持させる。ディスク11に吸着保持された固形製剤Tは、ディスク11の回転に伴って反時計方向に垂直回転移動される。
Next, the operation of the solid
次に、ディスク11に吸着された固形製剤Tの文字等の印刷、印刷検査及び修正印刷について図1、図2を参照して詳しく説明する。ディスク11は、ディスク12から直立姿勢の固形製剤Tの側面を吸着することにより受け取り、固形製剤Tを直立姿勢で吸着保持する。ディスク11が反時計方向に回転することにより、吸着保持した固形製剤Tを反時計方向に回転移動させる。固形製剤Tが印刷装置21及び印刷装置31が印刷できる位置に回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、印刷装置21によって固形製剤Tの第1面に文字等を印刷し、印刷装置31によって固形製剤Tの第2面に文字等を印刷する。印刷装置21及び印刷装置31は共に、インクジェットプリンターで構成され、ディスク11の回転方向に略直交する方向に1列に配列した複数のノズルからインクを吐出することにより、回転移動中の固形製剤Tに所定の文字等を印刷することができる。文字等は予め図示しない印刷データ記憶装置に記憶されていて、適宜、図示しない制御装置が所定の文字等の印刷データを指示して印刷装置21及び印刷装置31を制御する。
Next, the printing of characters and the like of the solid preparation T adsorbed on the
なお、印刷装置21及び印刷装置31におけるノズル列は、1列に限定するものではなく、複数のノズル列を有するものであってもよい。また、印刷装置21及び印刷装置31は、インクジェットプリンターに限定されるものではなく、レーザープリンターでもタンポ印刷装置でもスクリーン印刷装置であってもよい。
The nozzle rows in the
印刷された固形製剤Tは、さらに反時計方向にディスク11が回転することにより回転移動を継続させられる。撮像装置41及び撮像装置51が撮像できる位置に固形製剤Tが回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、撮像装置41が回転移動中の固形製剤Tの第1面を撮像し、撮像装置51が回転移動中の固形製剤Tの第2面を撮像する。撮像装置41及び撮像装置51は共にCMOSセンサーで構成され、電子シャッタとストロボを使用して回転移動中の固形製剤Tをぶれないように撮像する。撮像装置41及び撮像装置51で撮像された画像は、図示しない検査装置に送られ、各面に印刷された文字等の検査を行なう。その際、検査装置は、制御装置から当該固形製剤Tの文字等の印刷に使用された印刷データを受け取り、当該固形製剤Tの印刷に使用した印刷データと当該印刷文字等とを重ねて比較して検査を行なう。そして検査装置は、印刷不良と判断した固形製剤Tの不良内容と不良個所を特定する。
The printed solid preparation T is further rotated by the
すなわち、当該固形製剤Tの印刷に使用した印刷データと当該印刷文字等の撮像画像とを重ねて比較し、欠け、滲み、又はずれ等のいずれかの不良があるかを判断する。つまり、当該印刷文字等の一部に印刷の欠如がある場合は、当該印刷不良の内容を欠け不良と判断するとともに不良個所を特定する。また、印刷データ以外の部分に余分な印刷個所がある場合は、当該印刷不良を滲み不良と判断するとともに滲み不良個所を特定する。さらに、当該印刷文字等が本来印刷されなければならない位置が大きくずれている場合は、当該印刷不良をずれ不良と判断するとともにずれ不良個所を特定する。また、複数の不良内容が存在する場合は、存在する不良内容全てについての不良内容と不良個所を特定する。 That is, the print data used for printing the solid preparation T and the captured image such as the printed characters are overlapped and compared to determine whether there is any defect such as chipping, bleeding, or misalignment. That is, when there is a lack of printing in a part of the print character or the like, the content of the print defect is determined as a lack defect and a defective part is specified. In addition, when there is an extra print location in a portion other than the print data, the print failure is determined to be a bleeding failure and the bleeding failure location is specified. Further, when the position where the print character or the like should be printed is greatly deviated, it is determined that the print defect is a misalignment and the misalignment location is specified. In addition, when there are a plurality of defect contents, the defect contents and the defect locations for all the existing defect contents are specified.
実施例1においては、欠け不良がある場合について詳しく説明する。図3(a)に印刷データを示す。この印刷データに基づき印刷した結果、図3(b)に示すような印刷文字等の画像が撮像されたとする。検査装置は、当該印刷文字等の撮像画像と印刷データの画像とを重ねて比較し差分画像を演算する。図3(c)に差分画像の例を示す。当該印刷文字等が印刷データによって正しく印刷されておれば、差分画像はゼロ、すなわち真っ白な画像を表示するように制御される。ところが、当該印刷文字等の撮像画像と印刷データの画像とに異なる部分が存在すれば、差分画像には当該異なる部分が黒く表示される。この黒く表示された領域内の画素数をカウントし、予め設定された閾値以上であれば、不良と判断する。そしてこの閾値以上の黒表示の部分が印刷される文字等の領域内であれば、不良内容を欠け不良と判断する。また、この欠け不良の個所、すなわち、閾値以上の画素数を有する黒表示領域を不良個所と特定する。しかし、黒表示ではあるが閾値未満の画素数で構成される領域は白表示に変更する。これは、検査が厳しくなり過ぎないよう配慮したものである。そして、当該黒表示領域の不良個所を示す画像を不良個所画像として制御装置に記憶する。 In the first embodiment, a case where there is a chipping defect will be described in detail. FIG. 3A shows print data. As a result of printing based on this print data, it is assumed that an image such as a print character as shown in FIG. The inspection apparatus calculates the difference image by superimposing the captured image such as the print character and the image of the print data. FIG. 3C shows an example of the difference image. If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image. The number of pixels in the area displayed in black is counted, and if it is equal to or greater than a preset threshold value, it is determined as defective. If the black display portion equal to or greater than this threshold is within the area of the character to be printed, the defective content is determined to be defective. In addition, a black display area having the number of defective pixels, that is, the number of pixels equal to or greater than a threshold value is specified as a defective portion. However, an area composed of the number of pixels that are black but less than the threshold value is changed to white display. This is to prevent the inspection from becoming too strict. And the image which shows the defective part of the said black display area is memorize | stored in a control apparatus as a defective part image.
印刷検査の次に、固形製剤Tは修正印刷装置61及び修正印刷装置71が印刷可能な位置に回転移動させられるが、印刷不良と判断されなかった固形製剤Tは、修正印刷することなくさらに回転させられて収納箱17に収納される。
After the print inspection, the solid preparation T is rotated and moved to a position where the
印刷不良と判断された固形製剤Tには修正印刷装置61及び修正印刷装置71により修正印刷が施される。つまり、修正印刷装置61及び修正印刷装置71が印刷できる位置に固形製剤Tが回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、当該固形製剤Tが印刷不良と判断されたものであれば、修正印刷装置61によって回転移動中の固形製剤Tの第1面に修正印刷を施し、修正印刷装置71によって回転移動中の固形製剤Tの第2面に修正印刷を施す。修正印刷装置61及び修正印刷装置71は共に、2つの異なる色を吐出可能にインクジェットプリンターで構成されている。具体的には、修正印刷装置61及び修正印刷装置71をそれぞれ2つのインクジェットプリンターで構成し、それぞれ文字等の色及び固形製剤Tと同色の2種類のインクを選択吐出可能に構成している。
The solid preparation T determined to be defective in printing is subjected to correction printing by the
実施例1においては、欠け不良の固形製剤Tが回転搬送されると、上述の制御装置に記憶されている不良個所画像の黒表示領域にのみ、固形製剤Tに文字等の色のインクを吐出して欠け部分に
インクを補充する。これにより固形製剤Tの欠け部分にインクが補充されて欠けがなくなり当該固形製剤Tを救済することができる。救済された固形製剤Tは、印刷不良と判断されなかった固形製剤Tと同様に収納箱17に収納される。
In Example 1, when the defective solid preparation T is rotated and transported, ink of a color or the like is ejected onto the solid preparation T only in the black display area of the defective portion image stored in the control device. Then refill the missing part with ink. As a result, ink is replenished to the chipped portion of the solid preparation T, the chipping disappears, and the solid preparation T can be relieved. The rescued solid preparation T is stored in the
なお、実施例1においては、印刷装置21及び印刷装置31、撮像装置41及び撮像装置51、修正印刷装置61及び修正印刷装置71というように固形製剤Tの回転移動方向に各装置を配置して、印刷不良となった固形製剤Tを救済する構成としたが、必ずしもこれに限定されず、固形製剤印刷機の都合により適宜変更が可能である。例えば、印刷装置21及び印刷装置31と撮像装置41及び撮像装置51を備える構成とし、不良となった固形製剤Tは不良排出した後、再度、固形製剤印刷機100に投入して、印刷装置21及び印刷装置31を修正印刷装置と位置付けて修正印刷するように構成してもよい。
In Example 1, the devices are arranged in the rotational movement direction of the solid preparation T, such as the
また、実施例1においては、印刷装置21、印刷装置31で固形製剤Tの両面に文字等を印刷し、撮像装置41、撮像装置51で固形製剤Tの両面を撮像して印刷検査を行なうように構成したが、これに限定されず固形製剤印刷機の都合により適宜変更できる。例えば、いずれかの一方の面のみ文字等の印刷を行い、印刷を行った面のみ印刷検査を行ない、修正印刷するように構成してもよい。また、印刷する前に、固形製剤Tの外観検査を行なうようにしてもよい。さらに、ディスク12に第1面が吸着されている固形製剤Tの側面を撮像装置で撮像して外観検査を行なうように構成してもよい。
In Example 1, the
また、実施例1においては、ディスク11の回転に伴って吸着保持された固形製剤TはディスクTに対して位置がずれることがないため、制御装置に記憶された不良個所画像の黒表示領域に基づいて修正印刷装置61及び修正印刷装置71がインクを吐出して修正印刷するように構成した。また、ドラムやマガジンで固形製剤Tを搬送する場合も位置がずれることがほとんどないため同様の構成で修正印刷が可能である。しかし、コンベアにより固形製剤Tが搬送される場合は位置がずれる可能性があるため、修正印刷の前に固形製剤Tの位置認識を行い、固形製剤T又は不良個所画像の位置補正を行ってから修正印刷を行うように構成してもよい。
In Example 1, since the solid preparation T adsorbed and held with the rotation of the
以上のように、本発明の実施例1においては、固形製剤の表面に文字等を印刷する固形製剤印刷方法であって、印刷装置で文字等を印刷し、検査装置で印刷検査を行なうとともに印刷不良の固形製剤における不良内容と不良個所を特定し、修正印刷装置で当該不良個所に対して前記不良内容に応じた修正印刷を行うことを特徴とする固形製剤印刷方法により、印刷不良の固形製剤であっても無駄にしないで救済することができる。 As described above, the first embodiment of the present invention is a solid preparation printing method for printing characters or the like on the surface of a solid preparation, printing characters or the like with a printing apparatus, performing print inspection with an inspection apparatus and printing. A defective solid preparation is identified by a solid preparation printing method, wherein a defective content and a defective portion in a defective solid preparation are identified, and correction printing is performed on the defective portion with the correction printing apparatus according to the defective content. Even so, it can be remedied without wasting it.
また、固形製剤の表面に文字等を印刷する固形製剤印刷機であって、固形製剤に文字等を印刷する印刷装置と、印刷文字等を検査するとともに印刷不良の固形製剤における不良内容と不良個所を特定する検査装置と、当該不良個所に対して前記不良内容に応じた修正印刷を行う修正印刷装置と、前記印刷装置、前記検査装置、及び前記修正印刷装置を制御する制御装置とを備えたことを特徴とする固形製剤印刷機により、印刷不良の固形製剤であっても無駄にしないで救済することができる。 Moreover, it is a solid preparation printing machine that prints characters on the surface of a solid preparation, a printing device that prints letters etc. on the solid preparation, and inspection of the printed characters etc. An inspection device that identifies the defective portion, a correction printing device that performs correction printing according to the content of the defect, and a control device that controls the printing device, the inspection device, and the correction printing device. With the solid preparation printing machine characterized in that, even a solid preparation with poor printing can be remedied without being wasted.
本発明の実施例2は、印刷不良内容が滲み不良である点で実施例1と異なっている。以下、図4を参照して実施例2について説明する。図4は、本発明の実施例2における印刷滲み不良の例を説明する図である。図4(a)は、印刷データ、図4(b)は、滲み不良の撮像画像の例、図4(c)は、印刷データと滲み不良画像との差分画像の例を示している。 The second embodiment of the present invention is different from the first embodiment in that the printing defect content is a bleeding defect. Hereinafter, Example 2 will be described with reference to FIG. FIG. 4 is a diagram for explaining an example of a print blur defect in the second embodiment of the present invention. FIG. 4A shows print data, FIG. 4B shows an example of a picked-up image with poor bleeding, and FIG. 4C shows an example of a difference image between the print data and a defective blot image.
実施例2における固形製剤印刷機100の動作について、図1、図2を参照して説明する。実施例1と同様に、ディスク11は、ディスク12から直立姿勢の固形製剤Tの側面を吸着することにより受け取り、固形製剤Tを直立姿勢で吸着保持する。ディスク11が反時計方向に回転することにより、吸着保持した固形製剤Tを反時計方向に回転移動させる。固形製剤Tが印刷装置21及び印刷装置31が印刷できる位置に回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、印刷装置21によって回転移動中の固形製剤Tの第1面に文字等を印刷し、印刷装置31によって回転移動中の固形製剤Tの第2面に文字等を印刷する。印刷装置21及び印刷装置31は共に、インクジェットプリンターで構成され、ディスク11の回転方向に略直交する方向に1列に配列した複数のノズルからインクを吐出することにより、所定の文字等を固形製剤Tに印刷することができる。文字等は予め図示しない印刷データ記憶装置に記憶されていて、適宜、図示しない制御装置が所定の文字等の印刷データを指示して印刷装置21及び印刷装置31を制御する。
Operation | movement of the solid
印刷された固形製剤Tは、さらに反時計方向にディスク11が回転することに伴って回転移動が継続させられる。撮像装置41及び撮像装置51が撮像できる位置に固形製剤Tが回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、撮像装置41が回転移動中の固形製剤Tの第1面を撮像し、撮像装置51が回転移動中の固形製剤Tの第2面を撮像する。撮像装置41及び撮像装置51は共にCMOSセンサーで構成され、電子シャッタとストロボを使用して回転移動中の固形製剤Tをぶれないように撮像する。撮像装置41及び撮像装置51で撮像された画像は、図示しない検査装置に送られ、各面に印刷された文字等の検査を行なう。その際、検査装置は、制御装置から当該固形製剤Tの文字等の印刷に使用された印刷データを受け取り、当該固形製剤Tの印刷に使用した印刷データと当該印刷文字等とを重ねて比較して検査を行なう。そして検査装置は、印刷不良と判断した固形製剤Tの不良内容と不良個所を特定する。また、印刷不良とは判断しなかった固形製剤Tに対しては何もすることなく回転移動を継続させる。
The printed solid preparation T is continuously rotated as the
すなわち、当該固形製剤Tの印刷に使用した印刷データと当該印刷文字等とを重ねて比較し、欠け、滲み、又はずれ等のいずれかの不良があるかを判断する。実施例2においては、滲み不良がある場合について説明する。検査装置は、当該印刷文字等の撮像画像と印刷データの画像とを重ねて比較し差分画像を演算する(図4(c)参照)。当該印刷文字等が印刷データによって正しく印刷されておれば、差分画像はゼロ、すなわち真っ白な画像を表示するように制御される。ところが、当該印刷文字等の撮像画像と印刷データの画像とに異なる部分が存在すれば、差分画像には当該異なる部分が黒く表示される。この黒く表示された領域内の画素数をカウントし、予め設定された閾値以上であれば、不良と判断する。そしてこの閾値以上の黒表示の部分が印刷される文字等の領域外であれば、不良内容を滲み不良と判断する。また、この滲み不良の個所、すなわち、閾値以上の画素数を有する黒表示領域を不良個所と特定する。しかし、黒表示ではあるが閾値未満の画素数で構成される領域は白表示に変更する。これは、検査が厳しすぎることがないように配慮するためである。そして、当該黒表示領域の不良個所を示す画像を不良個所画像として制御装置に記憶する。 That is, the print data used for printing the solid preparation T is compared with the print characters and the like, and it is determined whether there is any defect such as chipping, bleeding or displacement. In the second embodiment, a case where there is a bleeding defect will be described. The inspection apparatus overlaps the captured image such as the print character and the image of the print data and calculates a difference image (see FIG. 4C). If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image. The number of pixels in the area displayed in black is counted, and if it is equal to or greater than a preset threshold value, it is determined as defective. If the black display portion equal to or greater than this threshold is outside the area of the printed character or the like, the defective content is determined to be blurred. In addition, a portion where the bleeding is defective, that is, a black display region having the number of pixels equal to or greater than the threshold is specified as a defective portion. However, an area composed of the number of pixels that are black but less than the threshold value is changed to white display. This is to ensure that the inspection is not too strict. And the image which shows the defective part of the said black display area is memorize | stored in a control apparatus as a defective part image.
印刷検査の次に、固形製剤Tは修正印刷装置61及び修正印刷装置71が印刷可能な位置に回転移動させられる。固形製剤Tが修正印刷装置61及び修正印刷装置71が印刷できる位置に回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、当該固形製剤Tが印刷不良と判断されたものであれば、修正印刷装置61によって回転移動中の固形製剤Tの第1面に修正印刷を施し、修正印刷装置71によって回転移動中の固形製剤Tの第2面に修正印刷を施す。修正印刷装置61及び修正印刷装置71は共に、2つの異なる色を吐出可能にインクジェットプリンターで構成されている。具体的には、修正印刷装置61及び修正印刷装置71をそれぞれ2つのインクジェットプリンターで構成し、それぞれ文字等の色及び固形製剤Tと同色の2種類のインクを選択吐出可能に構成している。
Following the print inspection, the solid preparation T is rotationally moved to a position where the
そして、滲み不良の固形製剤Tが回転移動されると、上述の不良個所画像の黒表示領域にのみ固形製剤Tと同色のインクを吐出して当該滲み部分にインクを重ねて修正印刷するように制御装置が制御する。これにより当該固形製剤Tにおける滲み部分が固形製剤Tの色と同じになって滲みがなくなり、印刷不良であった当該固形製剤Tを救済することができる。救済された固形製剤Tは、印刷不良と判断されなかった固形製剤Tと同様に収納箱17に収納されるように制御装置が制御する。
When the solid preparation T with poor bleeding is rotated and moved, the same color ink as that of the solid preparation T is ejected only in the black display area of the above-described defective portion image, and the ink is superimposed on the bleeding portion for correction printing. Controlled by the control device. Thereby, the bleeding part in the said solid formulation T becomes the same as the color of the solid formulation T, a blur disappears, and the said solid formulation T which was a printing defect can be relieved. The rescued solid preparation T is controlled by the control device so that the solid preparation T is stored in the
なお、固形製剤Tに滲み不良に加えて、欠け不良があると判断された場合は、両方の不良内容と不良個所が特定される。そして、修正印刷装置61及び修正印刷装置71にて、滲み不良部分に固形製剤Tと同色のインクを吐出するとともに、欠け部分に文字等の色のインクを吐出するように制御する。これによって、滲み不良及び欠け不良が救済される。
When it is determined that the solid preparation T has a defect in addition to a bleeding defect, both the defect content and the defect location are specified. Then, the corrected
このように実施例2においては、不良内容を滲み不良と特定するとともに当該不良個所を特定し、当該滲み部分に固形製剤Tと同色のインクを重ねて修正印刷することにより、文字等が滲んで印刷された固形製剤であっても無駄にしないで救済することができる。また、品質に影響のない汚れについても、同様の修正印刷することにより救済することができる。 As described above, in Example 2, the defective content is specified as a bleeding defect and the defective portion is specified, and correction printing is performed by overlaying the same color ink as the solid preparation T on the bleeding portion, thereby blurring characters and the like. Even a printed solid preparation can be saved without being wasted. Also, stains that do not affect the quality can be remedied by performing the same correction printing.
本発明の実施例3は、印刷不良内容がずれ不良である点で実施例1及び実施例2と異なっている。以下、図5を参照して実施例3について説明する。図5は、本発明の実施例3におけるずれ不良の例を説明する図である。図5(a)は、印刷データ、図5(b)は、ずれ不良の撮像画像の例、図5(c)は、印刷データとずれ不良画像との差分画像を示している。このずれ不良については、印刷文字等が本来印刷されるべき位置から大きくずれた不良内容であるので、一旦、固形製剤Tと同色のインクをずれ部分に修正印刷して排出した後、再度固形製剤印刷機に投入して再印刷することにより救済する。 The third embodiment of the present invention is different from the first and second embodiments in that the print defect content is misalignment. Hereinafter, Example 3 will be described with reference to FIG. FIG. 5 is a diagram for explaining an example of misalignment in the third embodiment of the present invention. FIG. 5A shows print data, FIG. 5B shows an example of a captured image with poor displacement, and FIG. 5C shows a difference image between the print data and the defective displacement image. Since this misalignment defect is a defect content in which the printed characters and the like are largely deviated from the positions to be originally printed, once the ink of the same color as the solid preparation T is corrected and printed on the misaligned portion and discharged, the solid preparation again Relief by putting it in the printing press and reprinting.
実施例3における固形製剤印刷機100の動作について図1、図2を参照して説明する。実施例1と同様に、ディスク11は、ディスク12から直立姿勢の固形製剤Tの側面を吸着することにより受け取り、固形製剤Tを直立姿勢で吸着保持する。ディスク11が反時計方向に回転することにより、吸着保持した固形製剤Tを反時計方向に回転移動させる。固形製剤Tが印刷装置21及び印刷装置31が印刷できる位置に回転させられると、図示しないセンサーにより固形製剤Tが検出されて、印刷装置21によって回転中の固形製剤Tの第1面に文字等を印刷し、印刷装置31によって回転中の固形製剤Tの第2面に文字等を印刷する。印刷装置21及び印刷装置31は共に、インクジェットプリンターで構成され、ディスク11の回転方向に略直交する方向に1列に配列した複数のノズルからインクを吐出することにより、所定の文字等を固形製剤Tに印刷することができる。文字等は予め図示しない印刷データ記憶装置に記憶されていて、適宜、図示しない制御装置が所定の文字等の印刷データを指示して印刷装置21及び印刷装置31を制御する。
Operation | movement of the solid
印刷された固形製剤Tは、さらに反時計方向にディスク11が回転することに伴って回転移動を継続させられる。撮像装置41及び撮像装置51が撮像できる位置に固形製剤Tが回転移動させられると、図示しないセンサーにより固形製剤Tが検出されて、撮像装置41が回転中の固形製剤Tの第1面を撮像し、撮像装置51が回転中の固形製剤Tの第2面を撮像する。撮像装置41及び撮像装置51は共にCMOSセンサーで構成され、電子シャッタとストロボを使用して画像がぶれないように撮像する。撮像装置41及び撮像装置51で撮像された画像は、図示しない検査装置に送られ、各面に印刷された文字等の検査を行なう。その際、検査装置は、制御装置から当該固形製剤Tの文字等の印刷に使用した印刷データを受け取り、当該固形製剤Tの印刷に使用した印
刷データと当該印刷文字等とを重ねて比較して検査を行なう。そして検査装置は、印刷不良と判断した固形製剤Tの不良内容と不良個所を特定する。印刷不良とは判断しなかった固形製剤Tについては、ここでは何もせずに回転移動を継続させる。
The printed solid preparation T is continuously rotated as the
すなわち、当該固形製剤Tの印刷に使用した印刷データと当該印刷文字等の撮像画像とを重ねて比較し、欠け、滲み、又はずれ等のいずれかの不良があるかを判断する。実施例3においては、ずれ不良がある場合について説明する。検査装置は、当該印刷文字等の撮像画像と印刷データの画像とを重ねて比較し差分画像を演算する(図5(c)参照)。当該印刷文字等が印刷データによって正しく印刷されておれば、差分画像はゼロ、すなわち真っ白な画像を表示するように制御される。ところが、当該印刷文字等の撮像画像と印刷データの画像とに異なる部分が存在すれば、差分画像には当該異なる部分が黒く表示される。この黒く表示された領域内の画素数をカウントし、予め設定された閾値以上を有する領域であれば不良と判断する。そしてこの閾値以上の黒表示領域が印刷されるべき文字等の領域外で、かつ当該黒表示領域の大きさが印刷されるべき文字等の大きさに近似していれば、不良内容をずれ不良と判断する。また、このずれ不良の個所、すなわち、閾値以上の画素数を有する黒表示領域を不良個所と特定する。しかし、黒表示ではあるが閾値未満である領域は白表示に変更する。これは、検査が厳しすぎることがないように配慮するためである。そして、当該黒表示領域の不良個所を示す画像を不良個所画像として制御装置に記憶する。 That is, the print data used for printing the solid preparation T and the captured image such as the printed characters are overlapped and compared to determine whether there is any defect such as chipping, bleeding, or misalignment. In the third embodiment, a case where there is a misalignment will be described. The inspection apparatus calculates a difference image by superimposing the captured image such as the print character and the image of the print data and comparing them (see FIG. 5C). If the print character or the like is correctly printed by the print data, the difference image is controlled to display zero, that is, a white image. However, if there are different portions in the captured image such as the print character and the image of the print data, the different portion is displayed in black in the difference image. The number of pixels in the area displayed in black is counted, and if it is an area having a preset threshold value or more, it is determined as defective. If the black display area above the threshold is outside the area of the character to be printed and the size of the black display area approximates the size of the character to be printed, the defective content is misaligned. Judge. In addition, the black display area having the number of pixels that is equal to or larger than the threshold is specified as the defective portion. However, the area that is black but is less than the threshold is changed to white. This is to ensure that the inspection is not too strict. And the image which shows the defective part of the said black display area is memorize | stored in a control apparatus as a defective part image.
印刷検査の次に、固形製剤Tは修正印刷装置61及び修正印刷装置71が印刷可能な位置に回転移動させられる。固形製剤Tが修正印刷装置61及び修正印刷装置71が印刷できる位置に回転させられると、図示しないセンサーにより固形製剤Tが検出されて、不良と判断された固形製剤Tであれば、修正印刷装置61によって回転中の固形製剤Tの第1面に修正印刷を施し、修正印刷装置71によって回転中の固形製剤Tの第2面に修正印刷を施す。修正印刷装置61及び修正印刷装置71は共に、2つの異なる色を吐出可能に2つのインクジェットプリンターで構成されている。具体的には、それぞれ文字等の色及び固形製剤Tの同色の2種類のインクを選択吐出可能に構成している。
Following the print inspection, the solid preparation T is rotationally moved to a position where the
そして、ずれ不良の固形製剤Tが回転移動されると、上述の不良個所画像に基づいて固形製剤Tに固形製剤Tと同色のインクを吐出してずれ部分にインクを重ねて修正印刷する。これは、上述した制御装置に記憶している不良個所画像の黒表示部分のみにインクを吐出するように制御装置が制御することにより行うことができる。これによりずれ部分が固形製剤Tの色と同じになるためずれ不良がなくなり、当該固形製剤Tは救済される。つまり、印刷されていない初期状態と同じに戻すことができる。制御装置は、初期状態に戻った固形製剤Tを、再印刷選別装置16を制御して当該固形製剤Tを再印刷用収納箱18に収納させる。再印刷用収納箱16に収納された固形製剤Tは、任意のタイミングで再度、固形製剤印刷機100に投入して、印刷、検査、必要に応じて修正印刷を行う。なお、図2は、再印刷選別装置16の記載を省略している。
When the misaligned solid preparation T is rotated and moved, the ink of the same color as that of the solid preparation T is ejected onto the solid preparation T based on the above-described defective portion image, and the ink is superimposed on the misaligned portion for correction printing. This can be performed by the control device controlling so that ink is ejected only to the black display portion of the defective portion image stored in the control device described above. As a result, the misaligned portion becomes the same as the color of the solid preparation T, so there is no misalignment, and the solid preparation T is relieved. That is, it is possible to return to the same initial state that is not printed. The control device controls the
なお、実施例3においては、ずれ不良の固形製剤Tに対して、固形製剤Tと同色のインクを吐出してずれ部分にインクを重ねて修正印刷した後、再印刷用収納箱18に収納させ、再度、固形製剤印刷機100に投入して、印刷、検査、必要に応じて修正印刷を行うようにしたが、必ずしもこれに限定されず、固形製剤印刷機の都合により適宜変更が可能である。例えば、修正印刷装置61及び修正印刷装置71の固形製剤回転移動方向下流に別の印刷装置を配置して、救済された固形製剤Tに対して文字等を印刷するように構成してもよい。
In Example 3, the solid preparation T with poor displacement is ejected with ink of the same color as the solid preparation T and overlaid on the misaligned portion for correction printing, and then stored in the
また、ずれ不良に加えて、欠け不良及び滲み不良があると判断された場合は、全ての不良の不良内容と不良個所が特定される。そして、修正印刷装置61及び修正印刷装置71にて、ずれ不良部分及び滲み不良部分に固形製剤Tと同色のインクを吐出するとともに、欠け部分に文字等の色のインクを吐出するように制御する。これによって、ずれ不良、滲み不良、及び欠け不良が救済される。
If it is determined that there are a chipping defect and a bleeding defect in addition to the shift defect, the defect content and the defect location of all the defects are specified. Then, the
このように実施例3においては、不良内容をずれ不良と特定し、また当該不良個所を特定して、当該ずれ部分に固形製剤Tと同色のインクを重ねて修正印刷を行った後、文字等を再印刷することにより、文字等がずれて印刷された固形製剤Tであっても救済することができる。 As described above, in Example 3, the defect content is specified as misalignment, the defect location is identified, and after the correction printing is performed by overlaying the same color ink as that of the solid preparation T on the misalignment portion, characters, etc. Can be relieved even if it is a solid preparation T printed with characters or the like shifted.
本発明における固形製剤印刷方法及び固形製剤印刷機は、印刷文字等の印刷不良を救済する分野に幅広く適用することができる。 The solid preparation printing method and the solid preparation printing machine in the present invention can be widely applied to the field of relieving printing defects such as printed characters.
11:ディスク 12:ディスク 13:ディスク 14:パーツフィーダ 15:固形製剤投入部 16:再印刷選別装置 17:収納箱 18:再印刷用収納箱21:印刷装置 31:印刷装置 41:撮像装置 51:撮像装置 61:修正印刷装置 71:修正印刷装置 T:固形製剤 11: Disc 12: Disc 13: Disc 14: Parts feeder 15: Solid formulation input unit 16: Reprint sorting device 17: Storage box 18: Reprint storage box 21: Printing device 31: Printing device 41: Imaging device 51: Imaging device 61: correction printing device 71: correction printing device T: solid preparation
Claims (8)
The modified printing apparatus is configured to be able to select printing with ink of the same color as the solid preparation in addition to printing with ink of color such as letters, and the control apparatus is capable of selecting a solid preparation in which the defective content is a deviation of characters or the like. On the other hand, the correction printing apparatus is controlled so that the same color ink as the solid preparation is superimposed on the misaligned portion, and the reprint sorting apparatus is controlled to store the solid preparation in a reprinting storage box. The solid preparation printing machine according to any one of claims 5 to 7.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016126112A JP2017225785A (en) | 2016-06-25 | 2016-06-25 | Solid pharmaceutical printing method and solid pharmaceutical printing machine |
| JP2016-126112 | 2016-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2017221494A1 true WO2017221494A1 (en) | 2017-12-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP2017/012242 Ceased WO2017221494A1 (en) | 2016-06-25 | 2017-03-27 | Solid preparation printing method and solid preparation printer |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2017225785A (en) |
| TW (1) | TW201800267A (en) |
| WO (1) | WO2017221494A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2736041A1 (en) * | 2018-06-22 | 2019-12-23 | Rovi Contract Mfg S L | Device and procedure for identifying pharmaceutical containers (Machine-translation by Google Translate, not legally binding) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7300155B2 (en) * | 2019-06-19 | 2023-06-29 | フロイント産業株式会社 | Teaching device in solid preparation appearance inspection, and teaching method in solid preparation appearance inspection |
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| JP2004202962A (en) * | 2002-12-26 | 2004-07-22 | Toppan Forms Co Ltd | Printing system |
| JP2005101824A (en) * | 2003-09-24 | 2005-04-14 | Seiko Epson Corp | Printing system and printing apparatus |
| JP2006051733A (en) * | 2004-08-13 | 2006-02-23 | Sumitomo Rubber Ind Ltd | Printing system and printer |
| US20120132722A1 (en) * | 2004-06-14 | 2012-05-31 | Ackley Machine Corporation | Methods and systems for inspection and/or identification of pellet-shaped articles |
| JP2013121432A (en) * | 2011-12-09 | 2013-06-20 | Kyoto Seisakusho Co Ltd | Tablet printing device |
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2016
- 2016-06-25 JP JP2016126112A patent/JP2017225785A/en active Pending
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- 2017-03-27 WO PCT/JP2017/012242 patent/WO2017221494A1/en not_active Ceased
- 2017-05-17 TW TW106116333A patent/TW201800267A/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004202962A (en) * | 2002-12-26 | 2004-07-22 | Toppan Forms Co Ltd | Printing system |
| JP2005101824A (en) * | 2003-09-24 | 2005-04-14 | Seiko Epson Corp | Printing system and printing apparatus |
| US20120132722A1 (en) * | 2004-06-14 | 2012-05-31 | Ackley Machine Corporation | Methods and systems for inspection and/or identification of pellet-shaped articles |
| JP2006051733A (en) * | 2004-08-13 | 2006-02-23 | Sumitomo Rubber Ind Ltd | Printing system and printer |
| JP2013121432A (en) * | 2011-12-09 | 2013-06-20 | Kyoto Seisakusho Co Ltd | Tablet printing device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2736041A1 (en) * | 2018-06-22 | 2019-12-23 | Rovi Contract Mfg S L | Device and procedure for identifying pharmaceutical containers (Machine-translation by Google Translate, not legally binding) |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017225785A (en) | 2017-12-28 |
| TW201800267A (en) | 2018-01-01 |
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