WO2017220220A1 - Food supplement - Google Patents

Abstract

The invention relates to a food supplement which is provided, particularly for consumption or ingestion in the morning or in the evening. The invention also relates to a kit comprising two food supplements, wherein one of the food supplements is provided for consumption or ingestion in the morning and the other food supplement is provided for consumption or ingestion in the evening.

Description

 Dietary supplements

The invention relates to a dietary supplement, which is preferably intended for consumption or for taking in the morning or in the evening. The invention also relates to a kit comprising two nutritional supplements, one of which is intended for consumption or for consumption in the morning and the other dietary supplement for consumption or for taking in the evening.

DE 10 2011 008 478 AI relates to a holistic dietary supplement with physiological action consisting of mixtures of dried broccoli and dried vegetables and / or dried fruits. Preferably, the dietary supplement is a plant extract of pomegranate, parsley, algae, grape, hawthorn, witch hazel, arnica, stinging nettle, calendula, propolis, elderberry, pineapple, horse chestnut, Sanikel, wild garlic, aloe vera, horsetail, garlic, ginseng, ginkgo and / or Blackberry added.

DE 10 2014 1 18 772 A1 discloses an administration form comprising two units A and B, which can be administered independently of each other, wherein the units A and B each contain a fungus component and further at least two further substances selected from natural substance extracts, vitamins and minerals , wherein the units A and B differ from each other in their composition. Preferably, the plant extracts are selected from the group consisting of rosehip extract, grape seed extract, hawthorn fruit extract, melissa extract, yam root extract, soybean extract, red clover extract, ginseng extract, rose extract, artichoke extract, fennel extract and ginkgo extract, bamboo shoot extract, oat extract, nettle extract, broccoli extract and mixtures of two or more thereof.

DE 10 2015 009 525 AI relates to a dietary supplement which contains or consists of phyto-estrogens or phyto-estrogen metabolites in combination with theanine and optionally conventional excipients. The dietary supplement Extracts from plants and plant derivatives include, for example Ackermennig, alfalfa, aloe vera, amaranth, angelica, anise, barberry, basil, fruit of the laurel tree, bee pollen, birch, biscuit, blackberry, black cohosh, black walnut, Benediktendistel, female root, blue verbena, water hemp , Borage, Buchu, Buckthorn, Wolfstrapp, Big burdock, Sweet peppers, Cayenne, Caraway, Cascara sagrada, Catnip, Celery, Centaury, Chamomile, Chaparral, Chickweed, Chicory, Cinchona bark, Cloves, Coltsfoot, Comfrey, Corn beard, Dog grass, Common snowball, Culver Root, Cornflower, Cornflower, Damiana, Dandelion, Devil's Claw, Dong Quai, Echinacea, Helen's wort, Meerkat, Eucalyptus, Evening Primrose, Eyebright, Roman Chamomile, Fennel, Fenugreek, Figwort, Flaxseed, Garlic, Gentian, Ginger, Ginseng, Curcuma, Gotu Kola, Grindela squarrosa, Hawthorn, Hops, Andorn, Horseradish, Horsetail, Hoshouwu, Hydrangea, Hyssop, Iceland moss, Irishmoo, Jojoba, Juniper, Kelp, Lady's slipper, Lemongrass, Licorice, Lobelia, Mandrake, Marigold, Marjoram, Marshmallow, Mistletoe, Mullein, Mustard, Myrrh, Nettle, Oat straw, Creeping mahonia, Papaya, Parsley, Passion flower , Peaches, pearly mint, peppermint, periwinkle, plantain, swallow root, pokeweed, prickly pear, psyllium, quassia, purpurdost, red clover, red raspberry, sodium bentonite, rhubarb, rosehip, rosemary, rue, safflower, saffron, sage, St. John's wort, sarsaparilla, Sassafras, Saw Palmetto, Skullcap, Senega, Senna, Shepherd's purse, Slime elm, Spearmint, Giant perennial arum, Partridge berry, Stillingia, Strawberry, Taheebo, Thyme, Real Bearberry, valerian, violet, watercress, white oak bark, white pine bark, wild cherry, oak lettuce, yam, willow, cranberry, witch hazel, red betony, wormwood, yarrow, curly sorrel, bearberry, yucca and their combinations.

DE 20 2011 105 533 Ul discloses a nutrient composition according to Asian and Mediterranean nutritional concepts, comprising vitamins, trace elements, and omega-3 fatty acids, wherein the composition is present in at least two separate dosage forms of different composition, wherein a first dosage form as further active ingredients at least one extract selected from the group comprising grapevine, olive, and / or tomato extract comprises and wherein a second dosage form as further active ingredients at least one extract selected from the group comprising Goji berry, ginger and / or green tea Extract includes.

EP 1 781 330 B1 relates to compositions with a capillary active system with application-specific differentiability and synergistic potential for use in mammals, especially humans. Particular preferred compositions contain as agents of a system S 1 one or more substances selected from cysteine, methionine, biotin, zinc oxide, thiamine nitrate (Bl), calcium pantothenate (B5), silica, as an agent of a system S2 ginseng, brazil nut, amino acids or Mixtures thereof, being an S3 system, herbal extracts such as green tea, echinacea, schisandra, astragalus, reishi, shiitake, maistake, meadow clover, soya, cat claw, grape seed, broccoli, tomato, onion, cauliflower, citrus bioflavonoids, buckwheat or grapefruit. Also preferred are compositions in which an activator system KA L-arginine hydrochloride, a protector system KP agent from the group KP: folic acid; Pyridoxine HCL (B6); Cyanocobalamin (B12); Tocopherol (E); Grape seed oil, and or currant seed oil and an agent of the group KE are selected from Q10, nicotinic acid amide (niacin, B3) or mixtures thereof. WO 01/50886 Al relates to a dairy-free instant powder containing oligofructose and at least one further component selected from minerals, trace elements and plant extracts. Preferred herb extracts and / or fruit extracts are rosemary extract, gentian root extract, Siberian ginseng extract, ginseng extract, chamomile extract, lime blossom extract, Melissa leaf extract, hop cone extract, Guaranextrakt, extract of dill fruits, hibiscus extract, rosehip extract, lavender extract, and citrus peel extracts, such as lemon and / or orange peel extract, and / or Tea extracts, such as black tea extract, green tea extract and mate tea extract.

WO 02/067986 A2 discloses a regenerative drug comprising (a) a microorganism component comprising: (a) at least one type of apathogenic microorganism and / or (a2) at least one type of pathogenic or facultatively pathogenic microorganism; (b) a modulator component containing (bl) at least one enzyme; (b2) at least one GRAS (Generally Recognized As Safe) flavor or derivative thereof and / or (b3) at least one animal or plant extract or derivative thereof which is a compound with alcoholic, acid, ester, aldehyde , Acetal, phenolic, functional groups and / or with double bonds. It is particularly preferred if the extracts are of the following origin or contain the following components: aloe, annatto (seed), arnica, valerian, comfrey, birch leaves, bee pollen, stinging nettle, mushroom, dill, ivy, marshmallow, oak (bark), Spruce (needles), Gingko (leaves), Ginseng (root), Hamamelis (leaves) Henna, Hay flowers, Hibiscus, Hops, Coltsfoot, Ginger (root), St. John's wort, Cocoa, Coffee, Chamomile, Carrots, Garlic, Cola nut, Coriander, Caraway, Lavender, Linden (blossom), Dandelion, Mallow, Butcher's broom, Marjoram, Melissa, Oranges (peel), Orthosiphonis, Pepper, Pepper, Peppermint, Mushrooms, Rhubarb, Marigold, Rosemary, Horse chestnuts, Sage, Horsetail, Celandine, Black tea, Liquorice, juniper berries, hawthorn, wheat bran, cinnamon, algae, banana, benzo, birch tar, bochshorn, boldo, cinchona bark, copai balm, derris root, cajeput oil, gentian, eucalyptus, fennel, fuzzy, calamus, potato starch, pine, rosin , Onion, larch turpentine, flaxseed, bay leaf, softwood tar, Niduli tree, Peruvian balsam, Pyrethrum, Quassia wood, Rice, rotenone, Sadebaum, saponin, salsify, mustard, sesame, soy, coneflower, centaury, turpentine, plantain, white hellebore, wormwood, cypress, apple , Avocado, Theobroma grandiflorum, Grapefruit, Guarana, Cucumber, Oat, Melon, Jojoba, Kiwi, Burdock, Clover, Coconut, Cornflower, Almond, Mango, Mistletoe, Taxus, Papaya, Passion fruit, Peach, Yarrow, Cowslip, Sunflower, Deadnettle, Thyme, walnut, watermelon, ylang ylang, cochineal, beeswax, royal jelly, propolis, shellac, lecithin, formates, formic acid, lutein, canthaxanthin, riboflavin, lactoflavin, edible fatty acids and derivatives, angora, astrahan, cashmere, mohair, wool, milk , Casein, Caseinogen, Bee pollen, Bee venom, Honey, Whey, Eggs, Karatin, Placenta, Fish, Meat, Poultry, Ambra, Capiz, Caviar, Chitin, Coral, Squalene, Seal oil, Whale oil, Sponges, Pearls, Roes, Robbe , Bowls animals, sperm oil, Seed oil, wax, carmine, carminic acid, catgut, musk, civet, castor, estrogen, progesterone, testosterone, hormones, ivory, lanolin, mink oil, parchment, silk, snake venom, urea, amino acids, aspic, bones, bristles, collagen, down, Blood, gelatin, glycerine, fur, leather, oleostearin, rennet, stearin derivatives.

[0009] WO 2013/152055 A1 relates to a composition for alleviating radiation-induced life-shortening effects from exposure to a radiation source and the effects of oxidative stress, wherein the radiation-oxidative exposure treatment composition comprises: a mixture of micronutrient, multivitamin and trace elements Mixture of antioxidants and chemopreventive agents and optionally a mixture of fatty acids.

[0010] WO 2015/014497 AI relates to an edible product wherein the product comprises a layer of fibrous plant product and a plant extract applied thereto.

The dietary supplements known from the prior art are not satisfactory in every respect and there is a need for improved dietary supplements.

It is an object of the invention to provide nutritional supplements which have advantages over the prior art.

This object is solved by the subject matter of the claims.

A first aspect of the invention relates to a dietary supplement comprising

 (a) a mineral component;

 (b) a vitamin component; and

 (c) a plant extract component.

It has surprisingly been found that dietary supplements according to the invention have advantages in terms of the occurrence of headache, nausea, well-being, free breathing, eye irritation and performance, especially for subjects who live in urban habitats and thus sometimes exposed to increased air pollution are. These benefits were demonstrated in a study / observational study and the results are statistically significant.

For the purpose of the description, all percentages are given in weight percent (wt .-%), unless expressly stated otherwise. The expression "and / or" between Element A and Element B means (i) only element A, but not element B at the same time; (ii) only element B, but not element A at the same time; or (iii) element A and at the same time element B.

The mineral component of the dietary supplement according to the invention comprises at least one physiologically acceptable salt

 a cation selected from the group consisting of calcium, cobalt, iron, potassium, copper, magnesium, manganese, molybdenum, vanadium and zinc; and

 an anion selected from the group consisting of acetate, carbonate, chloride, fluoride, gluconate, iodate, iodide, oxalate, oxide, phosphate, phosphonate and sulfate; and

Preferably, the mineral component comprises a physiologically acceptable zinc salt, more preferably zinc sulfate, in particular zinc sulfate monohydrate, and / or a physiologically acceptable magnesium salt, more preferably magnesium carbonate, and / or a physiologically acceptable iron salt, more preferably iron gluconate.

The vitamin component of the dietary supplement according to the invention comprises at least one vitamin selected from the group consisting of vitamin A (retinol), vitamin Bi (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B4 (adenine, choline ), Vitamin B5 (pantothenic acid), vitamin Ββ (pyridoxine), vitamin B7 (biotin), vitamin Bs (adenosine phosphate), vitamin B9 (folic acid), vitamin bio (para-aminobenzoic acid, mixture of B vitamins), vitamin B11 (folic acid ), Vitamin B12 (cobalamin), vitamin B13 (orotic acid), vitamin B14 (mixture of vitamins Bio and Bu), vitamin B15 (pangamic acid), vitamin Bi6 (pyridoxine), vitamin Bn (amygdalin), vitamin B22, vitamin Βτ (carnitine ), Vitamin Βχ (para-aminobenzoic acid), vitamin C (ascorbic acid), vitamin D (cholecalciferol), vitamin E (tocopherol), vitamin H (biotin), vitamin K (phylloquinine, menaquinone), vitamin Q (ubiquinone, coenzyme Q10) and their derivatives, preferably tocopheryl acetate, riboflavin-5-phosphate.

In a preferred embodiment, the vitamin component comprises vitamin B2 and / or a vitamin B2 derivative, preferably riboflavin-5-phosphate, and / or vitamin C and / or vitamin E and / or a vitamin E derivative, preferably alpha- Tocopheryl acetate, and / or vitamin Q (ubiquinone, coenzyme Q10). Coenzyme Q10 is considered according to the invention as a vitamin.

The plant extract component of the dietary supplement according to the invention comprises at least one plant extract, more preferably at least two plant extracts, more preferably at least three plant extracts, wherein in each case the plant extract is an extract from a plant or plant parts selected from the group consisting of field horsetail, Adoniskraut, Alant, Aloe vera, anise, arnica, artichoke, eyebright, valerian, bearberry leaves, mugwort, comfrey, birch, birch leaves, bishop's cabbage, bitter clover, bittern, common sage, stinging nettle, echinacea, ivy, marshmallow, oak bark, angelica, gentian, gentian, eucalyptus, buckthorn bark , Fennel, Fever clover, Lady's mantle, Goosegiving, Ginkgo, Ginseng, Goldenrod, Green tea, Hamamelis, Toadstool, Houseleek, Bilberry leaves, Blueberry, Shepherd's purse, Elderberry, Elderflower, Hops, Coltsfoot, Indian psyllium, Ginger, Icelandic moss, St. John's wort, Chamomile, Pine needles, burdock, garlic, mullein, cumin, pumpkin seeds, lavender, toadflax, linseed, linden, dandelion, lungwort, lily-of-the-valley, marjoram butter, milk thistle, butcher's broom, squill, melissa, mistletoe, chaste tree, agrimony, olive oil, passion flower, butterbur, Peppermint, Rharbarb root, marigold, castor, rosemary, horse chestnut, saw palmetto, sage, sea buckthorn, chess horsetail, yarrow, cowslip, celandine, senna leaves, sunhat, sundew, ribwort, clover, pansy, licorice root, centaury, devil's claw, thyme, tormentil, grape skins, black cohosh, juniper, walnut, plantain, plantain, chicory, hawthorn, wormwood , Witch hazel and onion. Elderberry juice powder is considered according to the invention as a plant extract.

Preferably, the plant extract component comprises at least two, more preferably at least three different plant extracts, each of which is an extract from a plant or plant parts are independently selected from the group consisting of Echinacea, ginseng, green tea, elderberry, sage and grape skins.

In a preferred embodiment, the plant extract component comprises ginseng extract and / or green tea extract and / or grape peel extract and / or Echinacea extract and / or elderberry extract (elderberry juice powder) and / or sage leaves extract.

The weight proportion of the plant extract component is preferably in the range of 0.010 to 5.000 wt .-%, more preferably in the range of 0.015 to 4.000 wt .-%, more preferably in the range of 0.020 to 3.000 wt .-%, more preferably in the range from 0.025 to 2.000% by weight, most preferably in the range of 0.030 to 1.500% by weight, and especially in the range of 0.035 to 1.200% by weight, based in each case on the total weight of the dietary supplement.

In preferred embodiments, the dietary supplement according to the invention additionally

 (d) a sweetener component; and or

 (e) an acidulant component; and or

(f) an aroma component. In preferred embodiments, the dietary supplement according to the invention or consists of the dietary supplement according to the invention of components (a), (b) and (c); or (a), (b), (c) and (d); or (a), (b), (c) and (e); or (a), (b), (c) and (f); or (a), (b), (c), (d) and (e); or (a), (b), (c), (d) and (f); or (a), (b), (c), (e) and (f); or (a), (b), (c), (d), (e) and (f).

Preferably, the weight proportion of the sweetener component is at least 50% by weight, based on the total weight of the dietary supplement

Preferably, the weight fraction of the plant extract component is in the range of 0.01 to 5.0 wt .-%, based on the total weight of the dietary supplement.

[0029] The preferred sweetener component of the dietary supplement of the invention comprises

 at least one carbohydrate selected from the group consisting of sucrose, glucose, glucose syrup, invert sugar, fructose and maltodextrin; and or

 at least one sweetener selected from the group consisting of acesulfame, alitame, aspartame, aspartame-acesulfame salt, brazzein, cyclamate, dulcine, hernandulcine, lugdunam, monellin, neohesperidin, neotame, pentadine, saccharin, sucralose, stevioside, thaumatin; and or

 - At least one sugar substitute selected from the group consisting of sorbitol, mannitol, isomalt, maltitol, maltitol syrup, lactitol, xylitol and erythritol.

In a preferred embodiment, the dietary supplement according to the invention contains no sugar substitute.

The weight proportion of the sweetener component is preferably at least 50 wt%, more preferably at least 60 wt%, more preferably at least 70 wt%, even more preferably at least 75 wt%, most preferably at least 80 wt%. %, and in particular at least 85 wt .-%, each based on the total weight of the dietary supplement.

Preferably, the sweetener component comprises at least two carbohydrates and / or at least two sweeteners. Most preferably, the sweetening component comprises sucrose, maltodextrin, aspartame and acesulfame.

[0033] The preferred acidulant component of the dietary supplement according to the invention comprises at least one carboxylic acid selected from the group consisting of citric acid, tartaric acid and malic acid. Preferably, the acidulant component comprises citric acid.

The preferred flavor component of the dietary supplement according to the invention comprises at least one flavor selected from the group consisting of pineapple, apple, apricot (apricot), banana, pear, blackberry, strawberry, grapefruit, raspberry, cherry, kiwi, lime, lime , Mango, tangerine, melon, orange, papaya, passion fruit (passion fruit), peach, plum, quince, blackcurrant, gooseberry, tropic and lemon.

Preferably, the flavor component Tropic flavor and / or lime flavor and / or orange flavor.

In a particularly preferred embodiment of the dietary supplement according to the invention, hereinafter also referred to as "morning protection dietary supplement" comprises

 (a) the mineral component is a physiologically acceptable zinc salt; and or

 (b) the vitamin component

 Vitamin B2 or a vitamin B2 derivative, preferably ribiflavin-5-phosphate,

 - Vitamin C, and

 - Vitamin E or a vitamin E derivative, preferably alpha tocopheryl acetate; and or

 (c) the plant extract component ginseng extract, green tea extract and grape peel extract; and or

 (f) the flavor component Tropic Aroma.

Preferably, the morning-protection dietary supplement according to the invention, in each case based on the total weight of the dietary supplement,

 the weight fraction of the physiologically acceptable zinc salt is in the range of 0.033 ± 0.030% by weight, more preferably, more preferably in the range of 0.033 ± 0.025% by weight, most preferably in the range of 0.033 ± 0.020% by weight, and especially in the range from 0.033 ± 0.015 wt%; and or

the weight proportion of vitamin B2 or vitamin B2 derivative is in the range of 0.0010 ± 0.0008% by weight, more preferably in the range of 0.0010 ± 0.0007% by weight, more preferably in the range of 0.0010 ± 0.0006 wt%, most preferably in the range of 0.0010 ± 0.0005 wt%, and more preferably in the range of 0.0010 ± 0.0004 wt%; and or the weight proportion of vitamin C is in the range of 1.067 ± 1.000 wt%, more preferably in the range of 1.067 ± 0.800 wt%, even more preferably in the range of 1.067 ± 0.600 wt%, most preferably in the range of 1.067 ± 0.400 Wt .-%, and in particular in the range of 1.067 ± 0.2000 wt .-%; and or

 the proportion by weight of the vitamin E or the vitamin E derivative in the range of 0.080 ± 0.070% by weight, more preferably in the range of 0.080 ± 0.060% by weight, more preferably in the range of 0.080 ± 0.050% by weight, most preferably in Range of 0.080 ± 0.040 weight percent, and more particularly in the range of 0.080 ± 0.030 weight percent; and or

 the weight fraction of ginseng extract ranges from 0.167 ± 0.150% by weight, more preferably from 0.167 ± 0.130% by weight, more preferably from 0.167 ± 0.110% by weight, most preferably from 0.167 ± 0.090 Wt .-%, and in particular in the range of 0.167 ± 0.070 wt .-%; and or

 the weight fraction of green tea extract ranges from 0.083 ± 0.080% by weight, more preferably 0.083 ± 0.070% by weight, more preferably 0.083 ± 0.060% by weight, most preferably 0.083 ° 0.050 wt%, and more preferably in the range of 0.083 ± 0.040 wt%; and or

 the weight fraction of the grape peel extract is in the range of 0.167 ± 0.150% by weight, more preferably in the range of 0.167 ± 0.130% by weight, more preferably in the range of 0.167 ± 0.110% by weight, most preferably in the range of 0.167 ± 0.090 Wt .-%, and in particular in the range of 0.167 ± 0.070 wt .-%.

Preferred in the morning protection dietary supplement according to the invention, in each case based on the total content of zinc salt, vitamin B2 or its derivative, vitamin C, vitamin E or its derivatives, ginseng extract, green tea extract and grape peel extract,

 the weight proportion of the physiologically acceptable zinc salt is in the range of 2.1 ± 2.0% by weight, more preferably, more preferably in the range of 2.1 ± 1.5% by weight, most preferably in the range of 2.1 ± 1.0% by weight, and more preferably in the range of 2.1 ± 0.5% by weight; and or

 the weight proportion of vitamin B2 or vitamin B2 derivative is in the range of 0.10 ± 0.08% by weight, more preferably in the range of 0.10 ± 0.07% by weight, more preferably in the range of 0.10 ± 0.06 wt%, most preferably in the range of 0.10 ± 0.05 wt%, and more preferably in the range of 0.10 ± 0.04 wt%; and or

the proportion by weight of vitamin C in the range of 66.7 ± 50.0% by weight, more preferably in the range of 66.7 ± 40.0% by weight, more preferably in the range of 66.7 ± 30.0% by weight %, most preferably in the range of 66.7 ± 20.0 wt%, and more preferably in the range of 66.7 ± 10.0 wt%; and or the weight proportion of vitamin E or vitamin E derivative is in the range of 5.0 ± 4.0% by weight, more preferably in the range of 5.0 ± 3.2% by weight, more preferably in the range of 5.0 ± 2.4% by weight, most preferably in the range of 5.0 ± 1.6% by weight, and more preferably in the range of 5.0 ± 0.8% by weight; and or

 the weight proportion of the ginseng extract in the range of 10.4 ± 10.0% by weight, more preferably in the range of 10.4 ± 8.0% by weight, more preferably in the range of 10.4 ± 6.0% by weight .-%, most preferably in the range of 10.4 ± 4.0 wt .-%, and in particular in the range of 10.4 ± 2.0 wt .-%; and or

 the weight proportion of the green tea extract in the range of 5.2 ± 5.0% by weight, more preferably in the range of 5.2 ± 4.0% by weight, more preferably in the range of 5.2 ± 3.0 Wt .-%, most preferably in the range of 5.2 ± 2.0 wt .-%, and in particular in the range of 5.2 ± 1.0% by weight; and or

 the weight fraction of the grape peel extract in the range of 10.4 ± 10.0% by weight, more preferably in the range of 10.4 ± 8.0% by weight, more preferably in the range of 10.4 ± 6.0% by weight %, most preferably in the range of 10.4 ± 4.0% by weight, and more preferably in the range of 10.4 ± 2.0% by weight.

Preferably, the morning protection dietary supplement according to the invention, in each case based on an intended for administration, preferably in the morning, total amount of the dietary supplement,

 the included dose of the physiologically acceptable zinc salt is in the range of 5.0 ± 4.0 mg, more preferably, in the range of 5.0 ± 3.0 mg, most preferably in the range of 5.0 ± 2.0 mg, and in particular in the range of 5.0 ± 1.0 mg; and or

 the contained dose of Vitamin B2 or Vitamin B2 derivative is in the range of 0.21 ± 0.20 mg, more preferably in the range of 0.21 ± 0.16 mg, more preferably in the range of 0.21 ± 0.12 mg most preferably in the range of 0.21 ± 0.08 mg, and more preferably in the range of 0.21 ± 0.04 mg; and or

 the contained dose of vitamin C is in the range of 160 ± 150 mg, more preferably in the range of 160 ± 120 mg, more preferably in the range of 160 ± 90 mg, most preferably in the range of 160 ± 60 mg and especially in the range of 160 ± 30 mg; and or

the contained dose of Vitamin E or Vitamin E derivative is in the range of 12 ± 10 mg, more preferably in the range of 12 ± 8 mg, more preferably in the range of 12 ± 6 mg, most preferably in the range of 12 ± 4 mg, and especially in the range of 12 ± 2 mg; and or the dose of ginseng extract contained is in the range of 25 ± 24 mg, more preferably in the range of 25 ± 18 mg, more preferably in the range of 25 ± 12 mg, most preferably in the range of 25 ± 8 mg, and especially in the range of 25 ± 4 mg; and or

 the contained green tea extract dose is in the range of 12.5 ± 10 mg, more preferably in the range of 12.5 ± 8 mg, more preferably in the range of 12.5 ± 6 mg, most preferably in the range of 12.5 ± 4 mg, and especially in the range of 12.5 ± 2 mg; and or

 the contained dose of the grape peel extract is in the range of 25 ± 24 mg, more preferably in the range of 25 ± 18 mg, more preferably in the range of 25 ± 12 mg, most preferably in the range of 25 ± 8 mg, and especially in the range of 25 ± 4 mg.

Preferably, the morning protection dietary supplement according to the invention is intended for consumption or for ingestion in the morning.

In another particularly preferred embodiment of the dietary supplement according to the invention, hereinafter referred to as "evening regenerating dietary supplement" comprises

(a) the mineral component is a physiologically acceptable magnesium salt and a physiologically acceptable iron salt; and or

 (b) the vitamin component Vitamin Q; and or

 (c) the plant extract component Echinacea Extract, Elderberry Extract and Sage Leaf Extract; and or

 (f) the flavor component lime flavor and orange flavor.

Preferably, the evening regenerating dietary supplement according to the invention, in each case based on the total weight of the dietary supplement,

 the weight proportion of the physiologically acceptable magnesium salt is in the range of 0.667 ± 0.600% by weight, more preferably in the range of 0.667 ± 0.500% by weight, more preferably in the range of 0.667 ± 0.400% by weight, most preferably in the range of 0.667 ± 0.300 wt%, and more preferably in the range of 0.667 ± 0.200 wt%; and or

 the weight fraction of the physiologically acceptable iron salt ranges from 0.033 ± 0.030% by weight, more preferably 0.033 ± 0.025% by weight, more preferably 0.033 ± 0.020% by weight, most preferably 0.033 ± 0.015 wt%, and more preferably in the range of 0.033 ± 0.010 wt%; and or

the weight proportion of vitamin Q in the range of 0.033 ± 0.030% by weight, more preferably in the range of 0.033 ± 0.025% by weight, more preferably in the range of 0.033 ± 0.020% by weight, on most preferably in the range of 0.033 ± 0.015 wt%, and more preferably in the range of 0.033 ± 0.010 wt%; and or

 the weight fraction of Echinacea extract ranges from 0.333 ± 0.300% by weight, more preferably from 0.333 ± 0.250% by weight, more preferably from 0.333 ± 0.200% by weight, most preferably from 0.333 ± 0.150 % By weight, and more preferably in the range of 0.333 ± 0.100% by weight; and or

 the weight fraction of the elderberry extract ranges from 0.480 ± 0.450% by weight, more preferably from 0.480 ± 0.400% by weight, more preferably from 0.480 ± 0.350% by weight, most preferably from 0.480 ± 0.300 % By weight, and especially in the range of 0.480 ± 0.250% by weight; and or

 the weight fraction of the sage leaves extract ranges from 0.333 ± 0.300% by weight, more preferably from 0.333 ± 0.250% by weight, more preferably from 0.333 ± 0.200% by weight, most preferably from 0.333 ± 0.150 Wt .-%, and in particular in the range of 0.333 ± 0.100 wt .-%.

[0044] Preferred in the evening regenerating dietary supplement according to the invention, in each case based on the total content of magnesium salt, iron salt, vitamin Q, Echinacea extract and sage leaves extract,

 the proportion by weight of the physiologically acceptable magnesium salt in the range of 47.6 ± 45.0% by weight, more preferably in the range of 47.6 ± 36.0% by weight, more preferably in the range of 47.6 ± 27.0 Wt .-%, most preferably in the range of 47.6 ± 18.0 wt .-%, and in particular in the range of 47.6 ± 9.0 wt .-%; and or

 the proportion by weight of the physiologically acceptable iron salt in the range of 2.4 ± 2.0% by weight, more preferably in the range of 2.4 ± 1.6% by weight, more preferably in the range of 2.4 ± 1.2 Wt .-%, most preferably in the range of 2.4 ± 0.8 wt .-%, and in particular in the range of 2.4 ± 0.4 wt .-%; and or

 the weight proportion of vitamin Q in the range of 2.4 ± 2.0% by weight, more preferably in the range of 2.4 ± 1.6% by weight, more preferably in the range of 2.4 ± 1.2% by weight %, most preferably in the range of 2.4 ± 0.8% by weight, and more preferably in the range of 2.4 ± 0.4% by weight; and or

the weight proportion of Echinacea extract in the range of 23.8 ± 20.0% by weight, more preferably in the range of 23.8 ± 16.0% by weight, more preferably in the range of 23.8 ± 12.0% by weight %, most preferably in the range of 23.8 ± 8.0 wt%, and more preferably in the range of 23.8 ± 4.0 wt%; and or

the weight proportion of the sage leaf extract in the range of 23.8 ± 20.0% by weight, more preferably in the range of 23.8 ± 16.0% by weight, more preferably in the range of 23.8 ± 12.0% by weight .-%, at the most preferably in the range of 23.8 ± 8.0 wt%, and more preferably in the range of 23.8 ± 4.0 wt%.

Preferably, in the evening regenerating dietary supplement according to the invention, in each case based on a total amount of the dietary supplement intended for administration, preferably in the evening,

 the contained dose of the physiologically acceptable magnesium salt in the range of 100 ± 80 mg, more preferably in the range of 100 ± 72 mg, more preferably in the range of 100 ± 54 mg, most preferably in the range of 100 ± 36 mg, and especially in the range of 100 ± 18 mg; and or

 the contained dose of the physiologically acceptable iron salt is in the range of 5.0 ± 4.0 mg, more preferably in the range of 5.0 ± 3.2 mg, more preferably in the range of 5.0 ± 2.4 mg, most preferably in the range of Range of 5.0 ± 1.6 mg, and more particularly in the range of 5.0 ± 0.8 mg; and or

 the contained dose of vitamin Q is in the range of 5.0 ± 4.0 mg, more preferably in the range of 5.0 ± 3.2 mg, more preferably in the range of 5.0 ± 2.4 mg, most preferably in the range of 5.0 ± 1.6 mg, and more preferably in the range of 5.0 ± 0.8 mg; and or

 The contained dose of Echinacea extract is in the range of 50 ± 40 mg, more preferably in the range of 50 ± 32 mg, more preferably in the range of 50 ± 24 mg, most preferably in the range of 50 ± 16 mg, and most preferably in the range of 50 ± 8 mg; and or

 the contained dose of sage leaf extract is in the range of 50 ± 40 mg, more preferably in the range of 50 ± 32 mg, more preferably in the range of 50 ± 24 mg, most preferably in the range of 50 ± 16 mg, and especially in the range of 50 ± 8 mg.

The evening regenerating dietary supplement according to the invention is preferably intended for consumption or for taking in the evening.

The dietary supplement according to the invention is preferably present as a powder, but may also be present e.g. compacted, e.g. in the form of tablets or effervescent tablets.

Preferably, the dietary supplement according to the invention is packaged in units which are intended for consumption or for consumption.

Preferably, each intended for consumption or ingestion amount is in the range of 5 g to 100 g, more preferably in the range of 5 g to 25 g, each based on the total weight of the dietary supplement. Preferred units have a total weight in the range of 15 ± 12 g, more preferably in the range of 15 ± 10 g, even more preferably in the range of 15 ± 8 g, most preferably in the range of 15 ± 6 g, and especially in the range of 15 ± 4 g.

Preferably, the dietary supplement according to the invention has a physiological calorific value per 100 g in the range of 1625 ± 1600 kJ, more preferably in the range of 1625 ± 1300 kJ, even more preferably in the range of 1625 ± 1000 kJ, most preferably in the range of 1625 ± 700 kJ, and in particular in the range of 1625 ± 400 kJ.

Preferably, the dietary supplement according to the invention, based on the total weight, a fat content of at most 2.5% by weight, more preferably at most 0.5% by weight, more preferably at most 0.25 wt .-%, most preferably at most 0.10% by weight, and most preferably at most 0.05% by weight.

Preferably, the dietary supplement according to the invention, based on the total weight, a protein content of at most 2.5 wt .-%, more preferably at most 0.5 wt .-%, more preferably at most 0.25% by weight, most preferably at most 0.10% by weight, and most preferably at most 0.05% by weight.

Preferably, the dietary supplement according to the invention contains no sodium chloride.

A further aspect of the invention relates to a kit comprising at least one above-described morning protection dietary supplement according to the invention and at least one above-described evening regenerating dietary supplement according to the invention.

Another aspect of the invention relates to an above-described dietary supplement according to the invention

 (i) for use in the prevention or treatment of headache,

 (ii) for use in the prevention or treatment of nausea,

 (iii) for use in the prevention or treatment of eye irritation

 (iv) to improve well-being,

 (v) to improve free breathing, or

(vi) to improve performance. The invention is further illustrated by the following examples. However, these examples are not intended to be limiting.

Example 1 :

There were prepared powder mixtures with a total weight of 15000 mg and the following composition:

Morning Guard Nutritional Supplements:

[0060] Evening Regenerative Dietary Supplement:

Sucrose I sweetener

Citric Acid I Acidifier

Maltrodextrin I

 Magnesium carbonate A 100.00 mg magnesium

 Elderberries Elderberries

 I 72.00 mg

 Saftpulkver Saftpulkver

 Coenzyme Q10 A 5.00 mg coenzyme Q10

 Echinacea extract A 50.00 mg Echinacea extract

 Sage leaves extract A 50.00 mg sage leaves extract

 Iron gluconate A 5.00 mg iron

 Aroma lime I aroma

 Aroma Orange I aroma

 Aspartame I sweetener

Acesulfame KI sweetener I: physiologically inactive, A: physiologically active Example 2:

In a study / application observation over 2 months, 79 subjects were examined. Before and after the eight-week intake period, subjects were given a questionnaire (all with urban lounge with partially increased emissions). Here, the subjects had to answer questions about well-being, coughing, performance, ability to breathe freely and any existing irritation symptoms. Furthermore, heart rate and oxygen saturation were measured by finger clip before and after the period of use.

During the eight-week observation period, the subjects each took a heaped teaspoon of the preparations according to Example 1 (morning and evening application) dissolved in a glass of water.

A total of 79 subjects were included in the study. The subjects' ages ranged from 18-83 years with a 21-40 year old age peak (including a large group of students) and 61-80 year olds (a second group was recruited from hospitalized patients with various pre-existing conditions). The previous illnesses or risks of the latter patients in particular was chronic obstructive pulmonary disease (COPD) or bronchial asthma or prolonged nicotine abuse.

The values for the queried features were statistically compared by means of paired t-test. Only when considering the SpC values the Wilcoxon test was applied, as it can be assumed that a non-normal distribution.

The results are summarized below:

Headache:

 1-1 1-2 1-3

 Mean max frequency before after before after after before after

Total patients 2.73 1.94 4.16 3.09 2.10 1.51

Total result 2.73 1.94 4.16 3.09 2.10 1.51

 -29.17% -25.84% -28.31%

Mean value mean value mean value mean value mean value

Patients with 2.2142857 1.5892857

 2.79 1.77 4.30 3.11

 Pre-existing diseases 1 1

Total result 2.79 1.77 4.30 3.11 2.21 1.59 -36.54% -27.80% -28.23%

These results are also shown in Figures 1 A to C (each left before, right after).

Nausea:

These results are also shown in Figure 2 (left before, right after).

[0070] Well-being:

These results are also shown in Figure 3 (left before, right after).

Performance:

 4-1 4-2

 Medium max

 before afterwards after before

 Total patient 5.97 6.56 7.81 8.38

 Total result 5.97 6.56 7.81 8.38

 9.75% 7.29%

 Average mean value mean value mean value

Patients with pre-existing diseases 5,80357143 6,44642857 7,64285714 8,39285714

These results are also shown in Figure 4 (left before, right after).

Breathe:

These results are also shown in Figure 5 (left before, right after).

Cough:

 These results are also shown in Figure 6 (left before, right after).

[0078] Eye irritation:

 7-1

 before, afterwards

 Total patients 1.32 0.92

 Total result 1.32 0.92

 -29.81%

 Mean value mean

Patients with pre-existing conditions 1.25 0.83928571

These results are also shown in Figure 7 (left before, right after).

Peripheral oxygen saturation (SpC) and heart rate (HF):

These results are also shown in Figure 8 (left before, right after).

In summary, in the following table for each parameter the significance level (p <0.05 means statistically significant) and the respective mean values before (first value) and after (second value) summarized and the relative percentage change:

For the following features, therefore, the result before and after comparison was a significantly better result: headache, nausea, well-being, free breathing, eye irritation and performance. Also for the peripheral oxygen measurement a significantly better (higher) value was found.

By contrast, the values for the frequency of coughing were not different. This may be due to the fact that many of the ingredients just solve dust particles and mucus and thus this lytic process was rather triggered and so in the short term more likely cough or just unchanged cough frequency (similar to cough remedy) is expected. In general, the data therefore give a quite positive result. Particularly advantageous is the increase in peripheral oxygen saturation as well objectivatable, metrologically elevated, physiological parameters. The SpC provides information on the loading of red blood cells with oxygen and thus ultimately the supply of oxygen to the tissues. One can assume here that an improvement has taken place.

Claims

Claims: 1. A dietary supplement comprising  (a) comprising a mineral component comprising at least one physiologically acceptable salt  a cation selected from the group consisting of calcium, cobalt, iron, potassium, copper, magnesium, manganese, molybdenum, vanadium and zinc; and  an anion selected from the group consisting of acetate, carbonate, chloride, fluoride, gluconate, iodate, iodide, oxalate, oxide, phosphate, phosphonate and sulfate; and (b) a vitamin component comprising at least one vitamin selected from the group consisting of vitamin A (retinol), vitamin Bi (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B4 (adenine, choline), vitamin B5 (pantothenic acid), vitamin Ββ (pyridoxine), vitamin B7 (biotin), vitamin Bs (adenosine phosphate), vitamin B9 (folic acid), vitamin bio (para-aminobenzoic acid, mixture of B vitamins), vitamin bi 1 (folic acid), Vitamin B12 (cobalamin), vitamin B13 (orotic acid), vitamin B14 (mixture of vitamins Bio and B11), vitamin B 15 (pangamic acid), vitamin B6 (pyridoxine), vitamin Bn (amygdalin), vitamin B22, vitamin Βτ (carnitine) , Vitamin Βχ (para-aminobenzoic acid), vitamin C (ascorbic acid), vitamin D (cholecalciferol), vitamin E (tocopherol), vitamin H (biotin), vitamin K (phylloquinine, menaquinone), vitamin Q (ubiquinone, coenzyme Q10) and their derivatives; and  (c) a plant extract component comprising at least two different plant extracts, each of which is an extract of a plant or plant parts independently selected from the group consisting of echinacea, ginseng, green tea, elderberry, sage and grape skins. 2. The dietary supplement according to claim 1, wherein the plant extract component comprises at least three different plant extracts, each of which is an extract from a plant or plant parts independently selected from the group consisting of echinacea, ginseng, green tea, elderberry, sage and grape skins. The dietary supplement according to claim 1 or 2, wherein the plant extract component comprises ginseng extract and / or green tea extract and / or grape peel extract and / or Echinacea extract and / or elderberry extract and / or sage leaf extract. 4. The dietary supplement according to any one of the preceding claims, wherein the vitamin component comprises vitamin B2 and / or a vitamin B2 derivative and / or vitamin C and / or vitamin E and / or a vitamin E derivative and / or vitamin Q. 5. The dietary supplement according to any one of the preceding claims, wherein the mineral component comprises a physiologically acceptable zinc salt and / or magnesium salt and / or iron salt. 6. The dietary supplement according to any one of the preceding claims, wherein the weight proportion of the plant extract component in the range of 0.01 to 5.0 wt .-%, based on the total weight of the dietary supplement. 7. The dietary supplement according to any one of the preceding claims additionally comprising (d) comprising a sweetener component  at least one carbohydrate selected from the group consisting of sucrose, glucose, glucose syrup, invert sugar, fructose and maltodextrin; and or at least one sweetener selected from the group consisting of acesulfame, alitame, aspartame, aspartame-acesulfame salt, brazzein, cyclamate, dulcine, hernandulcine, lugdunam, monellin, neohesperidin, neotame, pentadine, saccharin, sucralose, stevioside, thaumatin; and or  - At least one sugar substitute selected from the group consisting of sorbitol, mannitol, isomalt, maltitol, maltitol syrup, lactitol, xylitol and erythritol. 8. The dietary supplement according to claim 7 wherein the weight proportion of the sweetener component is at least 50% by weight, based on the total weight of the dietary supplement. 9. The dietary supplement according to claim 7 or 8, wherein the sweetener component comprises at least two carbohydrates and / or at least two sweeteners. The dietary supplement of any one of claims 7 to 9, wherein the sweetening component comprises sucrose, maltodextrin, aspartame and acesulfame. 11. The dietary supplement according to any one of the preceding claims additionally comprising (e) an acidulant component comprising at least one carboxylic acid selected from the group consisting of citric acid, tartaric acid and malic acid. 12. The dietary supplement of claim 11, wherein the acidulant component comprises citric acid. 13. The dietary supplement according to any one of the preceding claims additionally comprising (f) an aroma component comprising at least one flavor selected from the group consisting of pineapple, apple, apricot, banana, pear, blackberry, strawberry, grapefruit, raspberry, cherry, kiwi, lime, lime, mango, mandarin, Melon, orange, papaya, passion fruit (passion fruit), peach, plum, quince, blackcurrant, gooseberry, tropic and lemon; and 14. The dietary supplement according to any one of the preceding claims, which is present as a powder. 15. The dietary supplement according to any one of claims 1 to 14, wherein  (a) the mineral component comprises a physiologically acceptable zinc salt; and or (b) the vitamin component  - Vitamin B2 or a vitamin B2 derivative,  - Vitamin C, and  - Vitamin E or a vitamin E derivative  includes; and or  (c) the plant extract component comprises ginseng extract, green tea extract and grape peel extract; and or  (f) the flavor component comprises tropic aroma. 16. The dietary supplement according to claim 15, wherein in each case based on the total weight of the dietary supplement  the proportion by weight of the physiologically acceptable zinc salt is in the range of 0.033 ± 0.030% by weight; and or  the weight proportion of vitamin B2 or vitamin B2 derivative is in the range of 0.0010 ± 0.0008% by weight; and or  the weight proportion of vitamin C is in the range of 1.067 ± 1.000% by weight; and or the proportion by weight of vitamin E or of the vitamin E derivative is in the range of 0.080 ± 0.070% by weight; and or the proportion by weight of the ginseng extract is in the range of 0.167 ± 0.150% by weight; and or the weight fraction of the green tea extract is in the range of 0.083 ± 0.080% by weight; and or  - The weight fraction of the grape peel extract in the range of 0.167 ± 0.150 wt .-% is. 17. The dietary supplement according to claim 15 or 16, wherein in each case based on the total content of zinc salt, vitamin B2 or its derivative, vitamin C, vitamin E or its derivatives, ginseng extract, green tea extract and grape peel extract,  the weight proportion of the physiologically acceptable zinc salt is in the range of 2.1 ± 2.0% by weight; and or  the weight proportion of vitamin B2 or vitamin B2 derivative is in the range of 0.10 ± 0.08% by weight; and or  the proportion by weight of vitamin C is in the range of 66.7 ± 50.0% by weight; and or the proportion by weight of vitamin E or of the vitamin E derivative is in the range of 5.0 ± 4.0% by weight; and or  the weight proportion of the ginseng extract is in the range of 10.4 ± 10.0% by weight; and or the weight proportion of the green tea extract is in the range of 5.2 ± 5.0% by weight; and or - The weight fraction of the grape peel extract in the range of 10.4 ± 10.0 wt .-% is. 18. The dietary supplement according to any one of claims 15 to 17, wherein in each case based on an intended for administration total amount of the dietary supplement the included dose of the physiologically acceptable zinc salt is in the range of 5.0 ± 4.0 mg; and or  - the contained dose of vitamin B2 or vitamin B2 derivative is in the range of 0,21 ± 0,20 mg; and or  - the dose of vitamin C contained is in the range of 160 ± 150 mg; and or  - the dose of vitamin E or vitamin E derivative contained is in the range of 12 ± 10 mg; and or  - the dose of ginseng extract contained is in the range of 25 ± 24 mg; and or - the dose of green tea extract contained is in the range of 12.5 ± 10 mg; and or - The contained dose of grape peel extract is in the range of 25 ± 24 mg. 19. The dietary supplement according to any one of claims 15 to 18, which is intended for consumption or for ingestion in the morning. 20. The dietary supplement according to any one of claims 1 to 14, wherein  (a) the mineral component comprises a physiologically acceptable magnesium salt and a physiologically acceptable iron salt; and or  (b) the vitamin component comprises vitamin Q; and or  (c) the plant extract component comprises Echinacea Extract, Elderberry Extract and Sage Leaf Extract; and or  (f) the flavor component comprises lime flavor and orange flavor. 21. The dietary supplement according to claim 20, wherein in each case based on the total weight of the dietary supplement  the weight proportion of the physiologically acceptable magnesium salt is in the range of 0.667 ± 0.600% by weight; and or  the weight fraction of the physiologically acceptable iron salt is in the range of 0.033 ± 0.030% by weight; and or  - The proportion by weight of vitamin Q is in the range of 0.033 ± 0.030% by weight; and or the weight proportion of Echinacea extract is in the range of 0.333 ± 0.300% by weight; and or  the weight fraction of elderberry extract is in the range of 0.480 ± 0.450% by weight; and or  - The proportion by weight of sage leaves extract in the range of 0.333 ± 0.300% by weight. 22. The dietary supplement according to claim 20 or 21, wherein in each case based on the total content of magnesium salt, iron salt, vitamin Q, Echinacea extract and sage leaves extract,  the weight proportion of the physiologically acceptable magnesium salt is in the range of 47.6 ± 45.0% by weight; and or  - The proportion by weight of the physiologically acceptable iron salt in the range of 2.4 ± 2.0 wt .-% is; and or  - The proportion by weight of vitamin Q is in the range of 2.4 ± 2.0% by weight; and or the weight proportion of Echinacea extract is in the range of 23.8 ± 20.0% by weight; and or - The proportion by weight of sage leaves extract in the range of 23.8 ± 20.0% by weight. 23. The dietary supplement according to any of claims 20 to 22, wherein, based in each case on a total amount of the dietary supplement intended for administration, the included dose of the physiologically acceptable magnesium salt is in the range of 100 ± 80 mg; and or  - The included dose of the physiologically acceptable iron salt is in the range of 5.0 ± 4.0 mg; and or  the contained dose of vitamin Q is in the range of 5.0 ± 4.0 mg, more preferably in the range of 5.0 ± 3.2 mg; and or  - the contained dose of Echinacea extract is in the range of 50 ± 40 mg; and or - The contained dose of sage leaf extract is in the range of 50 ± 40 mg. 24. The dietary supplement according to any one of claims 20 to 23, which is intended for consumption or for taking in the evening. 25. The dietary supplement according to any one of the preceding claims, wherein each intended for consumption or ingestion amount is in the range of 5 g to 100 g, based on the total weight of the dietary supplement. 26. The dietary supplement according to claim 25, wherein the amount is in the range of 5 g to 25 g. 27. A kit comprising at least one dietary supplement according to any one of claims 15 to 19 and at least one dietary supplement according to any one of claims 20 to 26.