[go: up one dir, main page]

WO2017191619A3 - A process for the preparation of a salt of sacubitril and valsartan - Google Patents

A process for the preparation of a salt of sacubitril and valsartan Download PDF

Info

Publication number
WO2017191619A3
WO2017191619A3 PCT/IB2017/052672 IB2017052672W WO2017191619A3 WO 2017191619 A3 WO2017191619 A3 WO 2017191619A3 IB 2017052672 W IB2017052672 W IB 2017052672W WO 2017191619 A3 WO2017191619 A3 WO 2017191619A3
Authority
WO
WIPO (PCT)
Prior art keywords
sacubitril
valsartan
preparation
salt
provides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2017/052672
Other languages
French (fr)
Other versions
WO2017191619A2 (en
Inventor
Siddamal Reddy PUTAPATRI
Bhushan Balasaheb KHAIRNAR
Ashok Kumar
Gyanendra Pandey
Kaptan Singh
Mohan Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Ltd
Original Assignee
Sun Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Industries Ltd filed Critical Sun Pharmaceutical Industries Ltd
Publication of WO2017191619A2 publication Critical patent/WO2017191619A2/en
Publication of WO2017191619A3 publication Critical patent/WO2017191619A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/31—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a process for the preparation of a salt of sacubitril and valsartan. Specifically, the present invention provides a process for the preparation of a sodium salt of sacubitril and valsartan.
PCT/IB2017/052672 2016-05-06 2017-05-08 A process for the preparation of a salt of sacubitril and valsartan Ceased WO2017191619A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201611015864 2016-05-06
IN201611015864 2016-05-06

Publications (2)

Publication Number Publication Date
WO2017191619A2 WO2017191619A2 (en) 2017-11-09
WO2017191619A3 true WO2017191619A3 (en) 2017-12-14

Family

ID=60202847

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2017/052672 Ceased WO2017191619A2 (en) 2016-05-06 2017-05-08 A process for the preparation of a salt of sacubitril and valsartan

Country Status (1)

Country Link
WO (1) WO2017191619A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210177803A1 (en) 2018-08-23 2021-06-17 Novartis Ag New pharmaceutical use for the treatment of heart failure
WO2020039394A1 (en) 2018-08-24 2020-02-27 Novartis Ag New drug combinations

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007056546A1 (en) * 2005-11-09 2007-05-18 Novartis Ag Pharmaceutical combinations of an angiotensin receptor antagonist and an nep inhibitor
US20130109729A1 (en) * 2007-11-12 2013-05-02 Novartis Ag Pharmaceutical composition
WO2017042700A1 (en) * 2015-09-07 2017-03-16 Sun Pharmaceutical Industries Limited Solid forms of valsartan and sacubitril

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007056546A1 (en) * 2005-11-09 2007-05-18 Novartis Ag Pharmaceutical combinations of an angiotensin receptor antagonist and an nep inhibitor
US20130109729A1 (en) * 2007-11-12 2013-05-02 Novartis Ag Pharmaceutical composition
WO2017042700A1 (en) * 2015-09-07 2017-03-16 Sun Pharmaceutical Industries Limited Solid forms of valsartan and sacubitril

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FENG, L ET AL.: "LCZ696: a dual-acting sodium supramolecular complex", TETRAHEDRON LETTERS, vol. 53, no. 33, 18 January 2012 (2012-01-18), pages 275 - 276, XP028393477 *

Also Published As

Publication number Publication date
WO2017191619A2 (en) 2017-11-09

Similar Documents

Publication Publication Date Title
TW201613859A (en) Analogs of PRIDOPIDINE, their preparation and use
SG11202103781TA (en) Products, uses & methods
GB2577981B (en) Methods, products & Uses relating thereto
WO2016071435A3 (en) Synthesis of copanlisib and its dihydrochloride salt
WO2015191945A3 (en) Solid state forms of sofosbuvir
EP3694499A4 (en) Novel process for the preparation of lifitegrast
IL260665B (en) Improved process for the preparation of osimertinib (azd9291) or a salt thereof, and " azd9291 aniline" or a salt thereof
GB201813648D0 (en) Methods, products & uses relating thereto
IL260011B (en) Water-soluble derivatives of 3,5-diphenyl-diazole compounds
SG11202103953TA (en) Organophosphorus compound, and preparation process and use thereof
WO2016042171A3 (en) A xanthene compound, and a colorant comprising the same
WO2015095659A3 (en) Indirubin solid dispersion composition
WO2016181204A8 (en) Method of making a mercury based compound, mercury based compound, methods of using the mercury based compound and uses of the mercury based compound
WO2017191619A3 (en) A process for the preparation of a salt of sacubitril and valsartan
EP3645008A4 (en) Substituted quinolinylcyclohexylpropanamide compounds and improved methods for their preparation.
NZ788612A (en) Process and intermediate for the preparation of oxetan-2-ylmethanamine
EP3353149A4 (en) The process of preparing indoline compounds and a novel indoline salt
WO2016125185A3 (en) Process for the preparation of 4-substituted-1-(trifluoromethoxy)benzene compounds
GB201912016D0 (en) Methods, products & uses relating thereto
GB201912021D0 (en) Methods, products & Uses relating thereto
EP3303319B8 (en) Derivatives of 1,2,3-triazolyl cyclohexan-1-ol and its use
WO2016030911A3 (en) Improved process for the preparation of lacosamide and its novel intermediate
WO2015118558A3 (en) Process for the preparation of clofarabine
WO2018193415A9 (en) Process for the preparation of pirlindole enantiomers and its salts
EP3676272A4 (en) Process for the preparation of ixazomib citrate

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17792595

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 17792595

Country of ref document: EP

Kind code of ref document: A2