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WO2017168593A1 - Instrument de jonction tissulaire - Google Patents

Instrument de jonction tissulaire Download PDF

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Publication number
WO2017168593A1
WO2017168593A1 PCT/JP2016/060252 JP2016060252W WO2017168593A1 WO 2017168593 A1 WO2017168593 A1 WO 2017168593A1 JP 2016060252 W JP2016060252 W JP 2016060252W WO 2017168593 A1 WO2017168593 A1 WO 2017168593A1
Authority
WO
WIPO (PCT)
Prior art keywords
curable material
tissue
treatment surface
discharge hole
puncture needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2016/060252
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English (en)
Japanese (ja)
Inventor
井上　晃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to PCT/JP2016/060252 priority Critical patent/WO2017168593A1/fr
Publication of WO2017168593A1 publication Critical patent/WO2017168593A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
    • A61B17/115—Staplers for performing anastomosis, e.g. in a single operation

Definitions

  • the present invention relates to a tissue connector.
  • a circular stapler is known as a tissue junction device for joining lumens (biological tissues) such as intestinal tracts (see, for example, Patent Document 1).
  • a circular stapler (surgical stapling instrument) described in Patent Literature 1 includes an insertion portion having a trocar shaft that can be inserted into a lumen and protruding from a distal end, and an anvil having an anvil shaft that is detachable from the trocar shaft.
  • the insertion portion can discharge staples from the tip toward the anvil via a plurality of staple discharge holes arranged in an annular shape, and can also enter the anvil from the inside of the plurality of staple discharge holes arranged in an annular shape.
  • the knife can be projected toward.
  • an anvil is inserted into one of the two lumens to be joined, and an anvil shaft is punctured into the inner wall of the one lumen and protrudes outward from the one lumen.
  • the insertion portion is inserted into the other lumen of the two lumens, and the trocar shaft is punctured into the inner wall of the other lumen and protrudes outside from the other lumen.
  • an anvil shaft is connected to a trocar shaft, and an anvil is attached with respect to an insertion part.
  • the staples are fired through the plurality of staple discharge holes, respectively, and the two lumens sandwiched between the distal end of the insertion portion and the anvil are joined to each other in an annular shape by the plurality of staples and inserted.
  • a knife is protruded from the tip of the part to cut the annular inner part.
  • the two lumens are joined in a state of communicating with each other.
  • This invention is made in view of the above, Comprising: It aims at providing the tissue junction device which can join the biological tissues made into joining object by simple operation.
  • a tissue connector according to the present invention is inserted into a body cavity and has a treatment surface for treating a living tissue at a distal end, and a projection protruding from the treatment surface. Puncture needles that simultaneously puncture target biological tissues and discharge a curable material on the tip side, and generate energy from the treatment surface and cure the curable material discharged from the discharge hole And an energy generating unit that joins the living tissues sandwiched between the cured curable material and the treatment surface.
  • the tissue connector according to the present invention has an effect that a pair of living tissues to be joined can be joined by a simple operation.
  • FIG. 1 is a diagram schematically showing a tissue joining system according to an embodiment of the present invention.
  • FIG. 2 is a view showing a distal end portion of the insertion portion shown in FIG.
  • FIG. 3 is a view showing a distal end portion of the insertion portion shown in FIG.
  • FIG. 4A is a diagram showing a procedure for joining lumens to be joined using the tissue joining system shown in FIG. 1.
  • FIG. 4B is a diagram showing a procedure for joining lumens to be joined using the tissue joining system shown in FIG. 1.
  • FIG. 4C is a diagram showing a procedure for joining lumens to be joined using the tissue joining system shown in FIG. 1.
  • FIG. 4D is a diagram showing a procedure of joining lumens to be joined using the tissue joining system shown in FIG. 1.
  • FIG. 4E is a diagram showing a procedure for joining lumens to be joined using the tissue joining system shown in FIG. 1.
  • FIG. 5 is a diagram showing a modification of the embodiment of the present invention
  • FIG. 1 is a diagram schematically showing a tissue joining system 1 according to an embodiment of the present invention.
  • the tissue joining system 1 is a system that joins two lumens (biological tissues) such as intestinal tracts to be joined without using staples and knives.
  • the tissue joining system 1 includes a tissue joining device 2, a control device 3, and a foot switch 4.
  • the tissue junction device 2 is an instrument that is grasped by an operator and joins two lumens to be joined.
  • the tissue connector 2 includes an operation unit 5 and an insertion unit 6.
  • the operation unit 5 is a part that the operator holds.
  • the operation unit 5 includes an injection handle 52 and a needle position adjustment unit 53 that are respectively attached to the base 51.
  • the injection handle 52 is pivotally supported with respect to the base 51 so as to be rotatable about an axis orthogonal to the paper surface of FIG. Then, the injection handle 52 causes the curable material CR (see FIG.
  • the needle position adjustment unit 53 is formed of a long member extending in the left-right direction in FIG. 1, and is attached to the base 51 so as to be rotatable around the central axis of the needle position adjustment unit 53. Then, the needle position adjusting unit 53 moves in the left-right direction in FIG. 1 according to the rotation operation by the operator, and changes the protruding dimension of the puncture needle 8 protruding from the distal end of the insertion unit 6.
  • FIGS. 1 to 3 are views showing the distal end portion of the insertion portion 6.
  • FIG. 2 is a perspective view showing a distal end portion of the insertion portion 6.
  • FIG. 3 is a cross-sectional view showing the distal end portion of the insertion portion 6.
  • the insertion portion 6 can be inserted into a lumen such as an intestinal tract, and a treatment surface 61 (FIG. 1) for treating (joining and separating) biological tissue is provided at the tip.
  • the insertion portion 6 includes a shaft 7, a puncture needle 8, a plurality of ultraviolet fibers 9 (FIGS. 2 and 3), and a heater portion 10 (FIG. 2).
  • FIG. 3 for convenience of explanation, a plurality of ultraviolet fibers 9 are shown as one member. The same applies to the drawings subsequent to FIG.
  • the shaft 7 is made of an insulating material, has a substantially cylindrical shape as shown in FIGS. 1 to 3, and has a base end (right end portion in FIG. 1) connected to the operation portion 5 (base 51). Yes. Further, the tip of the shaft 7 (left end portion in FIG. 1) is formed in a flat shape orthogonal to the central axis of the shaft 7 and constitutes a part of the treatment surface 61. Inside the shaft 7, as shown in FIG. 2 or FIG. 3, a puncture needle 8 and a plurality of ultraviolet fibers 9 are disposed. Although not specifically shown, the lead wire constituting the electric cable C (FIG. 1) connected to the control device 3 is arranged from the proximal end to the distal end via the operation unit 5 inside the shaft 7. It is installed.
  • the puncture needle 8 is disposed inside the shaft 7 so that a part thereof protrudes from the treatment surface 61.
  • the puncture needle 8 includes an injection tube 81 (FIG. 3) and a puncture needle main body 82.
  • the injection tube 81 is a portion into which the curable material CR (FIG. 3) is injected in advance.
  • the injection tube 81 includes a large diameter tube 811 and a small diameter tube 812.
  • the large diameter tube 811 is formed in a cylindrical shape having an outer diameter smaller than the inner diameter of the shaft 7, and is disposed inside the shaft 7 so as to be coaxial with the shaft 7.
  • the small-diameter pipe 812 has an outer diameter smaller than the inner diameter of the large-diameter pipe 811 and is formed in a cylindrical shape having the same length as the large-diameter pipe 811 and is coaxial with the large-diameter pipe 811. Arranged inside the large diameter tube 811.
  • the curable material CR is previously injected (injected in an uncured state) between the large diameter tube 811 and the small diameter tube 812.
  • the curable material CR is made of an ultraviolet curable resin.
  • the curable material CR is placed between the distal end side of the puncture needle 8 (the upper end side in FIG. 3) in accordance with the turning operation of the injection handle 52 by the operator. ) Is provided with an extrusion mechanism (not shown).
  • the proximal end (the lower end (not shown) in FIG. 3) of the injection tube 81 is connected to the needle position adjusting unit 53.
  • the puncture needle 8 advances and retreats along the central axis of the shaft 7 together with the needle position adjusting unit 53 with respect to the shaft 7 by the rotation operation of the needle position adjusting unit 53 by the operator. Thereby, the protrusion dimension from the treatment surface 61 in the puncture needle 8 is changed.
  • the puncture needle body 82 is a portion that punctures two lumens to be joined simultaneously.
  • the puncture needle main body 82 includes a base portion 821 and a needle tip portion 822.
  • the base portion 821 has a substantially columnar shape having an outer diameter dimension substantially the same as the inner diameter dimension of the small diameter tube 812, and the tip (the upper end portion in FIG. 3) protrudes from the small diameter tube 812. Fixed inside.
  • the needle tip portion 822 is provided at the distal end of the base portion 821 and has a conical shape in which the diameter of the bottom surface 8221 is substantially the same as the inner diameter of the large diameter tube 811.
  • the gap between the bottom surface 8221 of the needle tip 822 and the large diameter tube 811 is such that the large diameter tube 811 and the small diameter tube 812 are in accordance with the turning operation of the injection handle 52 by the operator.
  • a balloon 84 is attached between the bottom surface 8221 of the needle tip 822 and the large diameter tube 811 so as to cover the discharge hole 83 as shown in FIGS. 1 to 3. The balloon 84 expands as the curable material CR is discharged from the discharge hole 83. That is, the balloon 84 has a function as an expansion member according to the present invention.
  • the plurality of ultraviolet fibers 9 are portions that emit ultraviolet rays for curing the curable material CR, and are routed from the proximal end to the distal end between the shaft 7 and the puncture needle 8. And each front-end
  • an ultraviolet LED that emits ultraviolet rays is disposed on the proximal end side of the shaft 7 under the control of the control device 3. The ultraviolet light emitted from the ultraviolet LED is emitted from the treatment surface 61 via the plurality of ultraviolet fibers 9.
  • the heater unit 10 is a part that generates thermal energy and joins and separates living tissues, and has a function as an energy generation unit according to the present invention.
  • the heater unit 10 is made of a conductive material such as platinum, and is formed on the tip (treatment surface 61) of the shaft 7 by vapor deposition or the like. And the heater part 10 is provided with a pair of lead wire connection part 11 and the resistance pattern 12, as shown in FIG.
  • a material of the heater part 10 it is not restricted to platinum, You may employ
  • the heater unit 10 is not limited to a configuration formed by vapor deposition or the like, and a configuration in which stainless steel or the like is processed and bonded by thermocompression bonding may be employed.
  • the pair of lead wire connecting portions 11 are arranged so as to be substantially parallel to each other at the tip of the shaft 7.
  • the pair of lead wire connecting portions 11 are connected to lead wires (not shown) constituting the electric cable C routed inside the shaft 7.
  • One end of the resistance pattern 12 is connected (conducted) to one lead wire connecting portion 11 and extends from the one end along the annular shape of the tip of the shaft 7 while meandering in a wavy shape with a constant line width.
  • the end is connected (conductive) to the other lead wire connecting portion 11.
  • the resistance pattern 12 generates heat (generates thermal energy) when a voltage is applied (energized) to the pair of lead wire connecting portions 11 under the control of the control device 3.
  • the foot switch 4 is a portion operated by the operator with his / her foot, and accepts first and second operations by the operator. And the control apparatus 3 performs lighting control of the ultraviolet LED mentioned above according to 1st operation to the foot switch 4, and to the heater part 10 (resistance pattern 12) according to 2nd operation to the foot switch 4.
  • the energization control is executed. Note that the means for executing the lighting control and energization control is not limited to the foot switch 4, and other switches that are operated by hand may be employed.
  • the control device 3 includes a CPU (Central Processing Unit) and the like, and comprehensively controls the operation of the tissue connector 2 according to a predetermined control program. More specifically, the control device 3 executes lighting control for turning on the ultraviolet LED and emitting ultraviolet rays from the treatment surface 61 in accordance with the first operation of the foot switch 4 by the operator. Further, the control device 4 applies a voltage to the heater unit 10 (the pair of lead wire connection units 11) in response to the second operation of the foot switch 4 by the operator (energizes the resistance pattern 12), thereby treating the treatment surface. The energization control for generating heat energy from 61 is executed.
  • a CPU Central Processing Unit
  • a switch that receives the first operation (executes the above-described lighting control) and a switch that receives the second operation (executes the above-described energization control) may be provided separately, or A single switch that accepts both the first and second operations may be used.
  • the control device 3 performs the lighting control described above in response to the first operation (first operation) to the foot switch 4, and performs the next operation (second operation).
  • the above-described energization control is executed according to the operation).
  • FIG. 1 the operation which joins lumens, such as an intestinal tract used as joining object, using the tissue joining system 1 mentioned above is demonstrated.
  • FIG. 4E are diagrams showing a procedure for joining the first and second lumens LT1 and LT2 to be joined using the tissue joining system 1.
  • the operator inserts the insertion portion 6 into the first lumen LT1 among the two first and second lumens LT1 and LT2 such as the intestinal tract to be joined, and the puncture needle
  • the tip of 8 is punctured into the inner wall of the first lumen LT1 and protrudes outside the first lumen LT1.
  • the distal end portion of the large diameter tube 811, the balloon 84, and the needle tip portion 822 are in a state of protruding to the outside of the first lumen LT1.
  • the operator punctures the tip of the puncture needle 8 protruding outside the first lumen LT1 into the second lumen LT2 and protrudes outside the first lumen LT1.
  • the distal end portion of the large-diameter tube 811, the balloon 84, and the needle tip portion 822 are positioned inside the second lumen LT2.
  • the surgeon discharges the uncured curable material CR previously injected into the injection tube 81 from the discharge hole 83 by rotating the injection handle 52.
  • the opening direction of the discharge hole 83 is orthogonal to the central axis of the puncture needle 8, the curable material CR is discharged in a direction away from the central axis as shown by an arrow R1 in FIG.
  • the surgeon performs the first operation on the foot switch 4.
  • the control apparatus 3 performs lighting control according to 1st operation to the foot switch 4 by an operator, and radiates
  • the ultraviolet rays emitted from the treatment surface 61 pass through the first and second lumens LT1 and LT2 and the balloon 84, and are irradiated to the uncured curable material CR filled in the balloon 84. Then, the curable material CR filled in the balloon 84 is cured.
  • the operator reduces the protruding dimension of the puncture needle 8 from the treatment surface 61 by moving the needle position adjusting unit 53 (moves the puncture needle 8 in the direction of arrow R2 in FIG. 4D).
  • the balloon 84 is pulled toward the treatment surface 61 side at the bottom surface 8221 of the needle tip portion 822.
  • the first and second lumens LT1 and LT2 are sandwiched between the treatment surface 61 and the balloon 84 (cured material CR after curing).
  • the surgeon performs a second operation on the foot switch 4.
  • the control device 3 performs energization control in accordance with the second operation on the foot switch 4 by the operator, and generates thermal energy from the treatment surface 61.
  • the thermal energy generated from the treatment surface 61 is applied to the first and second lumens LT1 and LT2 sandwiched between the treatment surface 61 and the balloon 84 (cured material CR after curing).
  • bore LT1, LT2 is cut apart while the part according to the annular shape of the heater part 10 is joined (FIG. 4E). Thereafter, as shown in FIG.
  • the curable material CR is discharged from the discharge hole 83 provided on the distal end side of the puncture needle 8, and the curable material CR is cured.
  • the first and second lumens LT1 and LT2 are sandwiched between the cured curable material CR and the treatment surface 61, and thermal energy is applied from the treatment surface 61 to the sandwiched portion.
  • the first and second lumens LT1 and LT2 are joined. That is, by using the curable material CR, the first and second lumens LT1 and LT2 can be sandwiched without using a member corresponding to an anvil in a conventional circular stapler.
  • tissue connector 2 According to the tissue connector 2 according to the present embodiment, there is an effect that the first and second lumens LT1 and LT2 to be joined can be joined by a simple operation.
  • the balloon 84 is employed to restrict the flow of the curable material CR discharged from the discharge hole 83 inside the second lumen LT2. For this reason, it is possible to prevent the curable material CR from flowing unnecessarily inside the second lumen LT2.
  • the discharge hole 83 is provided so that the opening direction thereof is orthogonal to the central axis along the puncture direction of the puncture needle 8. Therefore, in the second lumen LT2, the flow of the curable material CR discharged from the discharge hole 83 is restricted by the balloon 84, and the balloon 84 is separated from the central axis (the arrow in FIG. 4C). It can be configured to expand in the (R1 direction).
  • the curable material CR can be efficiently positioned at a position facing the heater unit 10. Therefore, the parts of the first and second lumens LT1 and LT2 facing the heater unit 10 are brought into close contact with each other with the curable material CR and the treatment surface 61 after being cured, and heat energy is applied to the parts.
  • the first and second lumens LT1 and LT2 can be effectively joined and separated.
  • the protruding position of the puncture needle 8 from the treatment surface 61 can be changed by operating the needle position adjusting unit 53. For this reason, the distance between the balloon 84 (the curable material CR after curing) and the treatment surface 61 is adjusted, and the degree of adhesion between the first and second lumens LT1 and LT2 facing the heater unit 10 described above. Can be changed as appropriate. Further, before the puncture needle 8 is punctured into the first and second lumens LT1 and LT2, if the projecting dimension of the puncture needle 8 from the treatment surface 61 is set large in advance, the puncture can be easily performed. Can do.
  • an ultraviolet curable resin is employed as the curable material CR.
  • the curable material CR can be rapidly cured as compared with the case where a thermosetting resin is employed as the curable material CR. Therefore, the first and second lumens LT1 and LT2 can be joined in a short time.
  • the shape of the tissue connector 2 is not limited to the shape described in the above-described embodiment, and any other shape, for example, a shape in which the shaft 7 is curved as long as it has a similar function. You may have.
  • the thermal energy is applied when the first and second lumens LT1 and LT2 to be joined are joined and separated.
  • the present invention is not limited to this. It does not matter as a configuration for applying energy.
  • the discharge hole 83 is covered with the balloon 84, and the flow of the curable material CR into the second lumen LT2 is restricted by the balloon 84.
  • the present invention is not limited to this.
  • the balloon 84 may be removed when the curable material CR stays at a predetermined position inside the second lumen LT2 due to its own weight depending on the posture of the insertion portion 6. That is, in the present invention, the balloon 84 is not an essential configuration.
  • an ultraviolet curable resin is used as the curable material CR, but the present invention is not limited to this, and two liquids that are cured by mixing a thermosetting resin or a main liquid and a mixture.
  • a mixed curable resin may be used.
  • the thermosetting resin can be cured by the thermal energy from the heater unit 10, and the two-component mixed curing is performed.
  • the curing speed of the functional resin can be increased by the heat energy from the heater unit 10. That is, in such a case, irradiation with ultraviolet rays is not necessary, so that the ultraviolet LED or the ultraviolet fiber 9 may be omitted.
  • the projecting dimension of the puncture needle 8 from the treatment surface 61 can be changed (the puncture needle 8 can be advanced and retracted). May be adopted.
  • FIG. 5 is a diagram showing a modification of the embodiment of the present invention. Specifically, FIG. 5 corresponds to FIG. In the above-described embodiment, the discharge hole 83 is provided so that the opening direction thereof is orthogonal to the central axis along the puncture direction of the puncture needle 8.
  • the tissue joining system shown in FIG. You may comprise like 1A (insertion part 6A).
  • the tissue joining system 1A employs a puncture needle 8A different from the puncture needle 8 with respect to the tissue joining system 1 described in the above-described embodiment.
  • puncture needle 8A includes injection tube 81 described in the above-described embodiment and puncture needle body 82A.
  • puncture needle main body 82A the needle tip portion 822 is omitted from the puncture needle main body 82 described in the above-described embodiment.
  • puncture needle main body 82A has a configuration in which the distal end portion of base portion 821 described in the above-described embodiment is sharpened.
  • the gap between the large diameter tube 811 and the small diameter tube 812 at the distal end of the injection tube 81 corresponds to the large diameter tube 811 and the small diameter tube according to the turning operation of the injection handle 52 by the operator. It becomes a discharge hole 83A (FIG. 5) for discharging the curable material CR injected between 812 to the outside.
  • the opening direction of the discharge hole 83A (vertical direction in FIG. 5) is substantially parallel to the puncture direction (vertical direction in FIG. 5) of the puncture needle 8.
  • the balloon 84A is attached to the injection tube 81 so as to cover the discharge hole 83A. Also in this modified example as described above, the same effects as those of the above-described embodiment can be obtained.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un instrument de jonction tissulaire (2) comportant : une partie d'insertion (6) qui est insérée dans une cavité corporelle et qui présente, à son extrémité distale, une surface de traitement (61) pour traiter un tissu vivant ; une aiguille de ponction (8) faisant saillie depuis la surface de traitement (61) de façon à percer simultanément des tissus vivants à joindre, et qui présente, sur son côté extrémité pointe, un trou d'évacuation pour évacuer un matériau durcissable depuis ce dernier ; et une unité de génération d'énergie qui génère de l'énergie depuis la surface de traitement (61), rigidifie le matériau durcissable évacué par le trou d'évacuation, et joint les tissus vivants qui sont pincés entre le matériau durcissable rigidifié et la surface de traitement (61).
PCT/JP2016/060252 2016-03-29 2016-03-29 Instrument de jonction tissulaire Ceased WO2017168593A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2016/060252 WO2017168593A1 (fr) 2016-03-29 2016-03-29 Instrument de jonction tissulaire

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Application Number Priority Date Filing Date Title
PCT/JP2016/060252 WO2017168593A1 (fr) 2016-03-29 2016-03-29 Instrument de jonction tissulaire

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WO2017168593A1 true WO2017168593A1 (fr) 2017-10-05

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021516091A (ja) * 2018-05-23 2021-07-01 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 組織切除のためのデバイス、システム、及び方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003526412A (ja) * 1999-12-14 2003-09-09 インテグレイテッド ヴァスキュラー インターヴェンショナル テクノロジーズ エル シー ロック式圧縮プレート吻合装置
JP2009535100A (ja) * 2006-04-26 2009-10-01 イルミンオス・メディカル・インコーポレイテッド 骨に補強材を配送する装置および方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003526412A (ja) * 1999-12-14 2003-09-09 インテグレイテッド ヴァスキュラー インターヴェンショナル テクノロジーズ エル シー ロック式圧縮プレート吻合装置
JP2009535100A (ja) * 2006-04-26 2009-10-01 イルミンオス・メディカル・インコーポレイテッド 骨に補強材を配送する装置および方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021516091A (ja) * 2018-05-23 2021-07-01 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 組織切除のためのデバイス、システム、及び方法
US11419624B2 (en) 2018-05-23 2022-08-23 Boston Scientific Scimed, Inc. Devices, systems and methods for tissue resection
JP7431166B2 (ja) 2018-05-23 2024-02-14 ボストン サイエンティフィック サイムド，インコーポレイテッド 組織切除のためのデバイス、システム、及び方法

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