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WO2016178586A3 - Collagen compositions and preparation and uses thereof - Google Patents

Collagen compositions and preparation and uses thereof Download PDF

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Publication number
WO2016178586A3
WO2016178586A3 PCT/NZ2016/050069 NZ2016050069W WO2016178586A3 WO 2016178586 A3 WO2016178586 A3 WO 2016178586A3 NZ 2016050069 W NZ2016050069 W NZ 2016050069W WO 2016178586 A3 WO2016178586 A3 WO 2016178586A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
collagen compositions
tissues
compositions
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NZ2016/050069
Other languages
French (fr)
Other versions
WO2016178586A2 (en
Inventor
Dipika Vandravanbhai PATEL
Charles Ninian MCGHEE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Auckland Uniservices Ltd
Original Assignee
Auckland Uniservices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auckland Uniservices Ltd filed Critical Auckland Uniservices Ltd
Publication of WO2016178586A2 publication Critical patent/WO2016178586A2/en
Publication of WO2016178586A3 publication Critical patent/WO2016178586A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C12N2537/10—Cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention encompasses compositions comprising collagen that may be used to repair or augment various tissues of the body, including eye tissues, and particularly, the tissues of the cornea. Also encompassed are methods of making and utilising these compositions.
PCT/NZ2016/050069 2015-05-01 2016-04-29 Collagen compositions and preparation and uses thereof Ceased WO2016178586A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ70768015 2015-05-01
NZ707680 2015-05-01

Publications (2)

Publication Number Publication Date
WO2016178586A2 WO2016178586A2 (en) 2016-11-10
WO2016178586A3 true WO2016178586A3 (en) 2017-02-09

Family

ID=57217682

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ2016/050069 Ceased WO2016178586A2 (en) 2015-05-01 2016-04-29 Collagen compositions and preparation and uses thereof

Country Status (1)

Country Link
WO (1) WO2016178586A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
EP2830627B1 (en) 2012-03-29 2024-05-01 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
EP2830637B1 (en) 2012-03-29 2024-08-21 Epion Therapeutics, Inc. Compositions and methods for treating or preventing diseases associated with oxidative stress
EP3509541B1 (en) 2016-09-12 2021-09-01 Gebauer-Klopotek Patent Verwaltungs-UG (haftungsbeschränkt) Lenticules for intrastromal corneal implantation
US12350144B2 (en) 2018-07-02 2025-07-08 Gebauer-Klopotek Patent Verw Altungs-Ug Stabilization of collagen scaffolds
WO2020008258A2 (en) * 2018-07-02 2020-01-09 Gebauer-Klopotek Patent Verwaltungs-Ug Stabilization of collagen scaffolds
US20200000962A1 (en) * 2018-07-02 2020-01-02 Medtronic Vascular, Inc. Load bearing crowded collagen constructs
WO2020010330A1 (en) * 2018-07-06 2020-01-09 The Trustees Of Columbia University In The City Of New York Collagen tissue modification
US12121630B2 (en) 2018-09-04 2024-10-22 Massachusetts Eye And Ear Infirmary Light activated adhesive scaffold
US20220001074A1 (en) * 2018-10-16 2022-01-06 The Schepens Eye Research Institute, Inc. Bioadhesive for Soft Tissue Repair
EP3880234A4 (en) * 2018-11-13 2022-08-10 Northeastern University Liquid crystalline collagen materials and use in connective tissue repair
GB201914250D0 (en) * 2019-10-02 2019-11-13 Ucl Business Ltd Biomaterial construct and methods of production thereof
WO2021097524A1 (en) * 2019-11-18 2021-05-27 The University Of Sydney Collagen gel formulations
AU2020410995A1 (en) * 2019-12-27 2022-07-21 Gebauer- Klopotek Patent Verwaltungs-UG (haftungsbeschränkt) Stabilization of collagen scaffolds
GB202001285D0 (en) * 2020-01-30 2020-03-18 Univ Newcastle Novel tissues and methods of making the same
US11752482B2 (en) * 2020-02-21 2023-09-12 Research & Business Foundation Sungkyunkwan University Restructured hydrogel and preparing method of the same
CN113425900A (en) * 2020-03-23 2021-09-24 成都中科奥格生物科技有限公司 Glue water gel material and preparation method and application thereof
WO2022006076A1 (en) * 2020-07-01 2022-01-06 The Johns Hopkins University Ocular treatment compositions and methods
WO2022192967A1 (en) * 2021-03-18 2022-09-22 The University Of Sydney Bioengineered endothelial constructs
CN113136412A (en) * 2021-04-22 2021-07-20 浙江珂瑞康生物医疗科技有限公司 Biological load determination treatment liquid for biomedical material containing soluble protein
CN113354837B (en) * 2021-06-04 2022-03-25 南京鼓楼医院 Patterned inverse opal collagen hydrogel for in-vitro tissue scaffold construction and preparation method thereof
JP2024525479A (en) * 2021-07-02 2024-07-12 コンバンジョ・インコーポレイテッド Processes for making and using cellular fibronectin compositions
CN113599505A (en) * 2021-07-21 2021-11-05 天津市眼科医院 Application of collagen in preparation of medicine for treating/preventing high myopia
SE2151478A1 (en) * 2021-12-03 2023-06-04 Mehrdad Rafat Method of providing an implantable hydrogel material and an implantable hydrogel material
CN115337222B (en) * 2022-07-28 2023-08-25 爱美客技术发展股份有限公司 Hollow collagen structure, and preparation method and application thereof
CN116850345A (en) * 2023-08-01 2023-10-10 诺一迈尔（苏州）医学科技有限公司 Preparation method of transparent collagen film
CN117143256B (en) * 2023-10-27 2024-01-26 英特菲尔(成都)生物制品有限责任公司 Extracellular matrix protein for hair restoration and preparation method and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080131473A1 (en) * 2004-07-05 2008-06-05 Robert Brown Cell-Independent Fabrication of Tissue Equivalents
US20130337227A1 (en) * 2010-11-26 2013-12-19 Tokyo Institute Of Technology Non-fibrogenesis collagen material and a manufacturing method thereof
US20140193477A1 (en) * 2012-10-11 2014-07-10 Emory University Collagen based materials and uses related thereto
US20150004414A1 (en) * 2012-01-12 2015-01-01 Nippi, Incorporated Collagen structure, and method for producing collagen structure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080131473A1 (en) * 2004-07-05 2008-06-05 Robert Brown Cell-Independent Fabrication of Tissue Equivalents
US20130337227A1 (en) * 2010-11-26 2013-12-19 Tokyo Institute Of Technology Non-fibrogenesis collagen material and a manufacturing method thereof
US20150004414A1 (en) * 2012-01-12 2015-01-01 Nippi, Incorporated Collagen structure, and method for producing collagen structure
US20140193477A1 (en) * 2012-10-11 2014-07-10 Emory University Collagen based materials and uses related thereto

Also Published As

Publication number Publication date
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