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WO2016163023A1 - Solution cosmétique - Google Patents

Solution cosmétique Download PDF

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Publication number
WO2016163023A1
WO2016163023A1 PCT/JP2015/061205 JP2015061205W WO2016163023A1 WO 2016163023 A1 WO2016163023 A1 WO 2016163023A1 JP 2015061205 W JP2015061205 W JP 2015061205W WO 2016163023 A1 WO2016163023 A1 WO 2016163023A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
ascorbic acid
whitening effect
spots
kusumi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2015/061205
Other languages
English (en)
Japanese (ja)
Inventor
正敏 中西
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mt Cosmetics Inc
Original Assignee
Mt Cosmetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mt Cosmetics Inc filed Critical Mt Cosmetics Inc
Priority to PCT/JP2015/061205 priority Critical patent/WO2016163023A1/fr
Publication of WO2016163023A1 publication Critical patent/WO2016163023A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Definitions

  • the present invention relates to a essence capable of obtaining a good moisturizing feeling and having an excellent whitening effect.
  • oils with high water retention polyhydric alcohols, sugars, water-soluble polymers and the like are used as moisturizing agents.
  • a moisturizing cosmetic containing a general-purpose water-soluble polyhydric alcohol such as propylene glycol, 1,3 butylene glycol or glycerin has a drawback that the moisturizing effect is not durable (Japanese Patent Laid-Open No. 2006-131520: Patent Document 1) If the amount of the moisturizing agent is increased in order to enhance the moisturizing effect, the sticky feeling or the feeling at the time of application is often unfavorable in many cases.
  • Patent Document 2 proposes a moisturizing cosmetic that has no moisturizing effect and has an excellent moisturizing effect
  • Patent Document 3 proposes a sticky feeling.
  • moisturizing cosmetics that maintain a good feeling of use for a long time, but all of them have insufficient moisturizing effects.
  • an object of the present invention is to provide a cosmetic liquid that can obtain a good moisturizing feeling and has an excellent whitening effect.
  • the present inventor has conducted intensive research. As a result, it is ethoxydiglycol and propyleneglycol that have a great influence on the moisturizing feeling of the cosmetic liquid. If the propylene glycol exceeds 30% by weight, the moisturizing feeling is too strong and sticky, while the ethoxydiglycol exceeds 50% by weight and the propylene glycol is less than 20% by weight. The present inventors have found that the moisturizing feeling is felt weak, the ethoxydiglycol content is 40% to 50% by weight, and the propylene glycol content is 20% to 30% by weight.
  • the present invention is based on such findings, and according to the present invention, the object of the present invention is to provide 40 wt% to 50 wt% ethoxydiglycol, 20 wt% to 30 wt% propylene glycol, Achievable by a cosmetic liquid comprising 10% to 20% by weight ascorbic acid and 1% to 10% by weight of 3-O-ethylascorbic acid, the balance being water.
  • the cosmetic liquid may contain inevitable impurities.
  • the whitening liquid according to the present invention further prevents the pores from conspicuous, prevents the pores from conspicuous, and is effective in contracting the pores.
  • a good moisturizing feeling can be obtained, and a essence with an excellent whitening effect can be provided.
  • the cosmetic liquid contains 45 wt% to 49 wt% ethoxydiglycol, 21 wt% to 25 wt% propylene glycol, 13 wt% to 17 wt% ascorbic acid, 3 wt%. % To 7% by weight of 3-O-ethylascorbic acid, the balance being water.
  • the water transpiration value of the upper right arm of 11 subjects was measured under an environment of a temperature of 24 ° C. and a humidity of 20% using a trade name “Tewameter (registered trademark) TM300” manufactured by Curage + Khazaka. .
  • essence sample # 1 was applied to the upper right arm of 11 subjects twice in the morning and evening, and after 1 month, using the product name “Tewameter (registered trademark) TM300” manufactured by Curage + Khazaka, The water transpiration value of the upper right arm of 11 subjects was measured under an environment of a temperature of 24 ° C. and a humidity of 20%.
  • the serum sample # 1 was subjected to a one-month use test on 30 women aged 25 to 55 years old with spots, freckles, and rashes on the face.
  • serum sample # 1 containing 47 wt% ethoxydiglycol, 23 wt% propylene glycol, 15 wt% ascorbic acid, 5 wt% 3-O-ethylascorbic acid and 10 wt% water is: It was found to have a good moisturizing effect and a good whitening effect.
  • Example 2 In the same manner as in Example 1, 50% by weight of ethoxydiglycol, 30% by weight of propylene glycol and 9% by weight of sterilized water were mixed with the cosmetic liquid as the final product. The mixture is heated to 70 ° C., 10% by weight ascorbic acid and 1% by weight 3-O-ethylascorbic acid are sequentially added to the mixture heated to 70 ° C., stirred, and cooled to 30 ° C. A serum sample # 2 was prepared.
  • serum sample # 2 containing 50 wt% ethoxydiglycol, 30 wt% propylene glycol, 10 wt% ascorbic acid, 1 wt% 3-O-ethylascorbic acid and 9 wt% water.
  • 30 was used, it was found that 28 out of 30 subjects showed improvement in spots and freckles, and 28 out of 30 subjects showed improvement in kusumi (improved transparency). Then, it was found that serum sample # 2 has a very good whitening effect.
  • Example 2 In the same manner as in Example 1, 40% by weight of ethoxydiglycol, 20% by weight of propylene glycol, and 10% by weight of sterilized water were mixed with the cosmetic liquid as the final product. The mixture is heated to 70 ° C., 20% by weight ascorbic acid and 10% by weight of 3-O-ethylascorbic acid are sequentially added to the mixture heated to 70 ° C., stirred, and cooled to 30 ° C. A serum sample # 3 was prepared.
  • the serum sample # 3 thus prepared was subjected to a one-month use test on 30 women aged 25 to 55 years old with spots, buckwheat and kusumi on the face.
  • serum sample # 3 containing 40 wt% ethoxydiglycol, 20 wt% propylene glycol, 20 wt% ascorbic acid, 10 wt% 3-O-ethylascorbic acid and 10 wt% water. It was found that 28 out of 30 subjects showed improvement in spots and freckles, and 29 out of 30 subjects showed improvement in kusumi (improved transparency). The serum sample # 3 was found to have a very good whitening effect.
  • Example 2 In the same manner as in Example 1, 46% by weight of ethoxydiglycol, 25% by weight of propylene glycol and 9% by weight of sterilized water were mixed with the cosmetic liquid as the final product. The mixture was heated to 70 ° C., 9 wt% ascorbic acid and 11 wt% 3-O-ethylascorbic acid were sequentially added to the mixture heated to 70 ° C., stirred, and cooled to 30 ° C. A serum comparison sample # 1 was prepared.
  • the comparative sample # 1 thus prepared was subjected to a one-month use test on 30 women aged 25 to 55 years old with spots, freckles and kusumi on the face.
  • Example 2 In the same manner as in Example 1, 44% by weight of ethoxydiglycol, 25% by weight of propylene glycol, and 10% by weight of sterilized water were mixed with the cosmetic liquid as the final product. The mixture was heated to 70 ° C. and 21 wt% ascorbic acid was added to the mixture heated to 70 ° C. and stirred, but ascorbic acid could not be dissolved.
  • the content of ascorbic acid was 10 wt% to 20 wt%, and the content of 3-O-ethylascorbic acid was 1 wt% to 10 wt%.
  • the serum samples # 1 to # 3 have a very good whitening effect, but the content of ascorbic acid is 9% by weight, which is less than 10% by weight.
  • the content of 3-O-ethylascorbic acid In the cosmetic liquid comparison sample # 1 containing 11% by weight of 3-O-ethylascorbic acid exceeding 10% by weight, it was found that there was almost no whitening effect.
  • ascorbic acid is dissolved even if an attempt is made to increase the content of ascorbic acid without adding 3-O-ethylascorbic acid and to contain 21% by weight of ascorbic acid exceeding 20%. It was found that the content of ascorbic acid was not more than 20% by weight and it was necessary to add 3-O-ethylascorbic acid instead of ascorbic acid.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une solution cosmétique qui peut donner une sensation humide satisfaisante et présente un excellent effet d'éclaircissement. La solution cosmétique selon la présente invention contient de 40 à 50 % en poids d'éthoxydiglycol, de 20 à 30 % en poids de propylène glycol, de 10 à 20 % en poids d'acide ascorbique, et de 1 à 10 % en poids d'acide 3-O-éthylascorbique (le complément étant constitué d'eau). De préférence, la solution cosmétique comprend de 45 à 49 % en poids d'éthoxydiglycol, de 21 à 25 % en poids de propylène glycol, de 13 à 17 % en poids d'acide ascorbique, de 3 à 7 % en poids d'acide 3-O-éthylascorbique, le complément étant constitué d'eau.
PCT/JP2015/061205 2015-04-10 2015-04-10 Solution cosmétique Ceased WO2016163023A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2015/061205 WO2016163023A1 (fr) 2015-04-10 2015-04-10 Solution cosmétique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2015/061205 WO2016163023A1 (fr) 2015-04-10 2015-04-10 Solution cosmétique

Publications (1)

Publication Number Publication Date
WO2016163023A1 true WO2016163023A1 (fr) 2016-10-13

Family

ID=57072206

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2015/061205 Ceased WO2016163023A1 (fr) 2015-04-10 2015-04-10 Solution cosmétique

Country Status (1)

Country Link
WO (1) WO2016163023A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018090149A1 (fr) * 2016-11-21 2018-05-24 Vivier Canada Inc. Formulations topiques à libération lente de putrescine

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004507561A (ja) * 2000-09-08 2004-03-11 ヴィヴィアー・カナダ・インコーポレーテッド 安定化されたアスコルビン酸溶液；その使用；その調製方法；およびそれを含む製剤
JP2004182635A (ja) * 2002-12-02 2004-07-02 Rohto Pharmaceut Co Ltd 皮膚外用剤
JP2005120023A (ja) * 2003-10-16 2005-05-12 Shiseido Co Ltd 皮膚外用剤
JP2010120879A (ja) * 2008-11-19 2010-06-03 Cosmetics Roorando Kk 皮膚外用剤およびその製造方法
JP2012162468A (ja) * 2011-02-04 2012-08-30 Mt Cosmetics Kk アスコルビン酸を配合した溶液及びその溶液の製造方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004507561A (ja) * 2000-09-08 2004-03-11 ヴィヴィアー・カナダ・インコーポレーテッド 安定化されたアスコルビン酸溶液；その使用；その調製方法；およびそれを含む製剤
JP2004182635A (ja) * 2002-12-02 2004-07-02 Rohto Pharmaceut Co Ltd 皮膚外用剤
JP2005120023A (ja) * 2003-10-16 2005-05-12 Shiseido Co Ltd 皮膚外用剤
JP2010120879A (ja) * 2008-11-19 2010-06-03 Cosmetics Roorando Kk 皮膚外用剤およびその製造方法
JP2012162468A (ja) * 2011-02-04 2012-08-30 Mt Cosmetics Kk アスコルビン酸を配合した溶液及びその溶液の製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018090149A1 (fr) * 2016-11-21 2018-05-24 Vivier Canada Inc. Formulations topiques à libération lente de putrescine

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