WO2016152194A1 - Guide wire - Google Patents

Abstract

This guide wire 1 is provided with a long flexible wire body 10 and with an extension section 3 which is connected to the proximal end of the wire body 10 and which is adapted to be displaced toward the proximal end relative to the wire body 10, thereby being brought to an extended state in which the overall length of the guide wire 1 is increased. The extension section 3 can adjust stepwise the overall length of the guide wire 1, and the extended state of the extension section 3 can be maintained.

Description

Guide wire

The present invention relates to a guide wire.

The guide wire introduces and guides catheters used for treatment of difficult surgical sites or treatment for the purpose of minimally invasive to the human body, angiographic examination and treatment in heart disease, etc. Is used.

As such a guide wire, one having a long wire main body and a tubular extension that can be attached to the proximal end portion of the wire main body is known (for example, see Patent Document 1).

In the guide wire (guide wire system) described in Patent Document 1, for example, the entire guide wire is mounted by attaching an extension to the wire body in a state where the wire body is partially inserted into the living body. The length can be extended.

However, in the guide wire described in Patent Document 1, in order to attach the extension part during the procedure, the procedure is temporarily interrupted and the extension part is attached. Further, the interruption time becomes relatively long, and the guide wire cannot be smoothly extended. As a result, the procedure itself takes longer time and the patient is burdened.

Furthermore, in the conventional guide wire, the extension portion and the wire body are fixed by fitting. For this reason, when repeatedly used, the fitting strength tends to decrease, and the extension portion and the wire main body tend to be insufficiently fixed.

US Pat. No. 4,827,941

An object of the present invention is to provide a guide wire that can quickly and smoothly extend the length of the guide wire and has excellent durability.

Such an object is achieved by the present inventions (1) to (11) below.
(1) A guide wire having a long and flexible wire body,
A guide wire comprising an extension portion connected to a base end portion of the wire main body and being extended to extend the entire length of the guide wire by being displaced toward the base end side with respect to the wire main body.

(2) The guide wire according to (1), wherein the extension part is capable of adjusting a degree of the extension state.

(3) The guide wire according to (1) or (2), wherein one of the wire body and the extension is inserted into the other.

(4) The guide wire according to any one of (1) to (3), further including a lock portion that maintains the extended state.

(5) The lock portion includes a convex portion provided on one of the wire body and the extension portion, and a concave portion provided on the other and engaged with the convex portion (4 ) Guide wire.

(6) The wire body and the extension are screwed together,
The guide wire according to any one of the above (1) to (5), wherein the extension portion is rotated with respect to the wire body about the axis of the wire body to be in the extended state.

(7) The guide wire according to any one of (1) to (5), wherein the extension portion is in the extension state when pulled to the proximal end side with respect to the wire body.

(8) The extension portion has a multi-tube structure having at least an inner tube and an outer tube,
The guide wire according to (7), wherein the inner tube and the outer tube are relatively movable along a longitudinal direction of the wire body.

(9) The guide wire according to (1) or (2), wherein the extension portion is configured by a foldable member and is deformable from a folded state to an unfolded state.

(10) a biasing portion that biases the extension toward the proximal direction;
The guide wire according to any one of the above (1) to (9), further comprising a restriction of a biasing force of the biasing part with respect to the extension part and a restriction part capable of releasing the restriction.

(11) The guide wire according to any one of (1) to (10), further including a separation preventing unit that prevents the extension unit from separating from the wire body in the extended state.

According to the present invention, the guide wire can be extended by a simple operation. Therefore, as compared with the conventional technique, the time required for the operation to be extended in the middle of the procedure can be remarkably shortened, and the length of the guide wire can be extended quickly and smoothly.

FIG. 1 is a partial longitudinal sectional view (schematic side view) showing a first embodiment of the guide wire of the present invention. 2 is a longitudinal sectional view showing an extension of the guide wire shown in FIG. 1, wherein (a) shows a shortened state, (b) shows a first extended state, and (c) shows a second. It is a figure which shows the extended state. FIG. 3 is a diagram for explaining a method of using the guide wire shown in FIG. 1 and shows a shortened state. FIG. 4 is a view for explaining a method of using the guide wire shown in FIG. 1, and shows a first extended state. FIG. 5 is a view for explaining a method of using the guide wire shown in FIG. 1 and shows a second extended state. FIG. 6: is a longitudinal cross-sectional view which shows the extension part with which 2nd Embodiment of the guide wire of this invention is equipped with (a) and (b). FIGS. 7A to 7C are longitudinal sectional views showing extensions provided in the third embodiment of the guide wire of the present invention. FIGS. 8A to 8C are longitudinal sectional views showing extensions provided in the fourth embodiment of the guide wire of the present invention. 9 (a) to 9 (c) are longitudinal sectional views showing extensions provided in the fifth embodiment of the guide wire of the present invention. 10 (a) to 10 (c) are longitudinal sectional views showing an extension portion provided in the sixth embodiment of the guide wire of the present invention. 11 (a) to 11 (c) are longitudinal sectional views showing extensions provided in the seventh embodiment of the guide wire of the present invention. 12 (a) and 12 (b) are longitudinal sectional views showing extensions provided in the eighth embodiment of the guide wire of the present invention. FIG. 13: is a longitudinal cross-sectional view which shows the extension part with which 9th Embodiment of the guide wire of this invention is equipped with (a) and (b). 14 (a) and 14 (b) are longitudinal sectional views showing extensions provided in the tenth embodiment of the guide wire of the present invention. FIGS. 15A to 15C are longitudinal sectional views showing extensions provided in the eleventh embodiment of the guide wire of the present invention. FIG. 16: is a longitudinal cross-sectional view which shows the extension part with which 12th Embodiment of (a) and (b) is equipped with the guide wire of this invention.

Hereinafter, the guide wire of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a partial longitudinal sectional view (schematic side view) showing a first embodiment of the guide wire of the present invention, and FIG. 2 is a longitudinal sectional view showing an extension of the guide wire shown in FIG. FIG. 4 is a diagram showing a shortened state, FIG. 4B is a diagram showing a first extended state, and FIG. 4C is a diagram showing a second extended state. 3 to 5 are views for explaining a method of using the guide wire shown in FIG.

In the following, for convenience of explanation, the right side with respect to the longitudinal direction of the guide wire in FIGS. 1 to 4 is referred to as “base end”, the left side is referred to as “tip”, the upper side is “up”, and the lower side is “ Say "below". 1 to 5 (the same applies to FIGS. 6 to 28), the length direction of the guide wire is shortened and the radial direction (thickness direction) of the guide wire is exaggerated for easy understanding. It is schematically shown, and the ratio between the length direction and the radial direction is different from the actual ratio.

A guide wire 1 shown in FIG. 1 is a guide wire for a catheter that is used by being inserted into the lumen of a catheter (including an endoscope), and is disposed on the proximal end side of the first wire 2 and the first wire 2. The wire main body 10 formed by joining the second wire 4 formed, the spiral coil 5 installed at the tip of the wire main body 10, and the extension portion 3 are provided.

The total length of the guide wire 1 is not particularly limited, but is preferably about 200 to 5000 mm.

The first wire 2 is composed of a flexible or elastic wire. In the present embodiment, the first wire 2 has an outer diameter constant portion 21 whose outer diameter is substantially constant, and a first taper that is located on the distal side of the outer diameter constant portion 21 and whose outer diameter gradually decreases in the distal direction. A portion 22, a distal-end outer diameter constant portion 26 positioned on the distal end side of the first taper portion 22, and a large-diameter portion located on the proximal end side of the outer-diameter constant portion 21 and having a larger outer diameter than the outer-diameter constant portion 21 24 and the 2nd taper part 23 which is located between the outer diameter constant part 21 and the large diameter part 24, and an outer diameter reduces gradually toward a front-end | tip direction. These are arranged in order of the distal end side outer diameter constant portion 26, the first taper portion 22, the outer diameter constant portion 21, the second taper portion 23, and the large diameter portion 24 from the distal end side of the first wire 2.

By forming the first taper portion 22 between the distal end side constant outer diameter portion 26 and the constant outer diameter portion 21, the rigidity (bending rigidity and torsional rigidity) of the first wire 2 is gradually increased in the distal direction. As a result, the guide wire 1 can obtain good stenosis and passability at the distal end, improve followability to the blood vessel and safety, and prevent bending and the like. can do.

Similarly to the first taper portion 22, the outer diameter constant portion 21 and the large diameter portion 24 are formed via the second taper portion 23, so that the rigidity (bending rigidity, torsional rigidity) of the first wire 2 is achieved. ) Can be gradually decreased toward the tip.

Note that the taper angle (the reduction rate of the outer diameter) of the first taper portion 22 (the same applies to the second taper portion 23) is constant along the longitudinal direction of the wire body 10, but may vary along the longitudinal direction. May be. For example, a portion in which a taper angle (an outer diameter reduction rate) and a relatively small portion are alternately formed a plurality of times may be used.

Further, the first taper portion 22 and the second taper portion 23 may have different taper shapes and taper angles.

In the first wire 2, the outer diameter constant part 26, the constant outer diameter part 21, and the large diameter part 24 have constant outer diameters along the wire longitudinal direction. The outer diameter of the tip side outer diameter constant portion 26 is substantially equal to the minimum outer diameter of the first taper portion 22, and the outer diameter of the outer diameter constant portion 21 is substantially equal to the maximum outer diameter of the first taper portion 22. In addition, it is substantially equal to the minimum outer diameter of the second taper portion 23. The outer diameter of the large diameter portion 24 is substantially the same as the maximum outer diameter of the second tapered portion 23.

As shown in FIG. 1, the distal end side outer diameter constant portion 26 has a flat plate shape, and can be used after being deformed into a desired shape (referred to as “reshape or shaping”). In general, in order to guide the distal end of a guide catheter or the like to a blood vessel shape, or to select and guide a blood vessel branch appropriately and smoothly, a doctor or the like previously sets the distal end of the guide wire to a desired shape. In this way, bending the tip of the guide wire into a desired shape is called reshaping. And by providing the distal end side outer diameter constant portion 26, reshaping can be performed easily and reliably, and the operability when the guide wire 1 is inserted into the living body is remarkably improved.

The distal end of the second wire 4 is joined to the proximal end of the first wire 2 (the proximal end of the large diameter portion 24). The second wire 4 is made of a flexible or elastic wire.

The method for joining the first wire 2 and the second wire 4 is not particularly limited. For example, the joining is performed by welding such as friction welding, spot welding using a laser, butting resistance welding such as upset welding, or a tubular joining member. Although there is a method, butt resistance welding is particularly preferable because it is relatively simple and high joint strength can be obtained.

In the present embodiment, the outer diameter of the second wire 4 is substantially constant. The outer diameter of the second wire 4 is substantially equal to the outer diameter of the large diameter portion 24 of the first wire 2. Thereby, when the base end of the large diameter part 24 of the 1st wire 2 and the front-end | tip of the 2nd wire 4 are joined, the outer diameter difference of both the wires 2 and 4 on the outer periphery of those joined parts (welded part) 6 A step is not generated, and a continuous surface can be formed. In addition, in this invention, the outer diameter of the 1st wire 2 and / or the 2nd wire 4 may change before and behind the junction part 6 not only in this.

The average outer diameter of the first wire 2 is smaller than the average outer diameter of the second wire 4. As a result, the guide wire 1 is highly flexible on the first wire 2 on the distal end side and relatively high on the second wire 4 on the proximal end side. And excellent operability (pushability, torque transmission, etc.).

Further, as shown in FIGS. 2A to 2C, a convex portion group 41a, a convex portion group 41b, and a convex portion group 41c are provided on the outer peripheral portion of the proximal end of the second wire 4.

These convex portion groups 41a to 41c are arranged at equal intervals in this order from the tip side. Since each convex portion group 41a to 41c has the same configuration, the convex portion group 41a will be representatively described below.

The convex group 41 a has a convex part 411 and a convex part 412. The convex portion 411 and the convex portion 412 are arranged apart from each other in the longitudinal direction of the second wire 4. Further, the convex portion 411 and the convex portion 412 have a flange shape that protrudes to the entire circumference of the second wire 4 in the circumferential direction. Further, the convex portion 411 and the convex portion 412 are semicircular when viewed in the longitudinal section of the second wire 4, and their surfaces are rounded.

Such convex portion groups 41a to 41c are portions that engage with concave portions 36 and 37 of the extension portion 3 to be described later. Further, the convex portion groups 41a to 41c and the concave portions 36 and 37 constitute a lock portion.

The constituent materials of the first wire 2 and the second wire 4 are not particularly limited, and for example, stainless steel (for example, SUS304, SUS303, SUS316, SUS316L, SUS316J1, SUS316J1L, SUS405, SUS430, SUS434, SUS444, SUS429, Various metal materials such as SUS430F, all types of SUS such as SUS302), piano wires, cobalt-based alloys, alloys showing pseudoelasticity (including superelastic alloys) can be used.

The constituent material of the first wire 2 is preferably an alloy (including a superelastic alloy) exhibiting pseudoelasticity, more preferably a superelastic alloy.

Since the superelastic alloy is rich in flexibility, has a resilience, and is difficult to bend, the guide wire 1 is sufficiently flexible at the tip side by configuring the first wire 2 with the superelastic alloy. Performance and bendability, improved followability to complicatedly curved / bent blood vessels, etc., improved operability, and even if the first wire 2 repeatedly bends / bends, Since the bend crease is not attached due to the resilience of the 1 wire 2, it is possible to prevent the operability from being lowered due to the bend crease on the first wire 2 during use of the guide wire 1.

Pseudoelastic alloys include any shape of stress-strain curve caused by tension, including those that can measure the transformation point of As, Af, Ms, Mf, etc., and those that cannot be measured. However, everything that returns to its original shape by removing stress is included.

The preferred composition of the superelastic alloy is a Ni—Ti alloy such as a Ni—Ti alloy of 49 to 52 atomic% Ni, a Cu—Zn alloy of 38.5 to 41.5 wt% Zn, 1 to 10 wt% X Cu—Zn—X alloy (X is at least one of Be, Si, Sn, Al, and Ga), Ni-Al alloy of 36 to 38 atomic% Al, and the like. Of these, the Ni—Ti alloy is particularly preferable. Note that a superelastic alloy typified by a Ni—Ti alloy is also excellent in the adhesion of a resin coating layer 8 described later.

The cobalt-based alloy has a high elastic modulus when used as a wire and has an appropriate elastic limit. For this reason, the wire comprised by the cobalt type alloy is excellent in torque transferability, and problems, such as buckling, do not arise very much. Any cobalt-based alloy may be used as long as it contains Co as a constituent element, but it contains Co as a main component (Co-based alloy: Co content in the elements constituting the alloy) Is preferable, and a Co—Ni—Cr alloy is more preferably used. By using an alloy having such a composition, the above-described effects become more remarkable. In addition, an alloy having such a composition has a high elastic modulus and can be cold-formed even as a high elastic limit, and by reducing the diameter while sufficiently preventing buckling from occurring due to the high elastic limit. And can have sufficient flexibility and rigidity to be inserted into a predetermined portion.

As the constituent material of the second wire 4, the above-mentioned stainless steel is preferable. Stainless steel has higher strength and rigidity than the superelastic alloy, and therefore can impart excellent pushability and torque transmission to the guide wire 1.

The first wire 2 and the second wire 4 may be made of different materials, but may be made of the same or the same kind of metal material (the main metal material in the alloy is the same). In the latter case, the joint strength of the joint portion (welded portion) 6 becomes higher, and even if the outer diameter of the joint portion 6 is small, excellent torque transmission properties and the like are exhibited without causing separation or the like.

When the first wire 2 and the second wire 4 are made of different materials, the first wire 2 is preferably made of the above-described superelastic alloy, and particularly made of a Ni—Ti alloy. The second wire 4 is preferably made of the above-described stainless steel.

In the above description, the first wire 2 and the second wire 4 are joined. However, the first wire 2 and the second wire 4 may be composed of a single continuous wire body without a joint. In this case, examples of the constituent material of the wire body include the same materials as described above, and stainless steel, cobalt-based alloys, and pseudoelastic alloys are particularly preferable.

The coil 5 is disposed on the outer periphery of the distal end portion of the wire body 10 so as to cover the distal end portion together with the distal end side outer diameter constant portion 26. The installation of the coil 5 reduces the contact area of the surface of the wire body 10 with the inner wall of the catheter and the surface of the living body, thereby reducing the sliding resistance. As a result, the operability of the guide wire 1 is further improved. improves.

As shown in FIG. 1, a wire main body 10 is inserted through the central portion inside the coil 5. In the case of the present embodiment, the distal end side outer diameter constant portion 26, the first taper portion 22, and all or part of the outer diameter constant portion 21 are covered with the coil 5.

Further, the distal end portion of the wire body 10 (particularly, the region from the distal end side outer diameter constant portion 26 to the first tapered portion 22) is inserted in a non-contact manner with the inner surface of the coil 5. As a result, a gap 50 is formed between the coil 5 and the tip of the wire body 10.

The coil 5 is formed by spirally forming a strand 54 having a circular cross section. In this case, one strand 54 may be spirally wound, or a plurality of strands 54 may be spirally wound.

The constituent material of the strand 54 is not particularly limited, and may be either a metal material or a resin material. Preferable examples of the metal material include X-ray opaque materials such as stainless steel, noble metals such as Au and Pt, and alloys containing the noble metals (for example, Pt—Ni alloys). In the latter case, X-ray contrast property is obtained at the distal end portion of the guide wire 1, and it can be inserted into the living body while confirming the position of the distal end portion under X-ray fluoroscopy, which is preferable.

The coil 5 may be a combination of two or more materials. For example, the strand 54 on the distal end side of the coil 5 can be made of an X-ray opaque material such as the Pt—Ni alloy, and the strand 54 on the proximal end side of the coil 5 can be made of stainless steel. In this case, under X-ray fluoroscopy, the part located on the distal end side of the coil 5 (particularly, the part including the distal end side outer diameter constant portion 26) is emphasized more than the part located on the proximal end side. Therefore, the position of the most distal portion of the guide wire 1 (the portion where the distal end side outer diameter constant portion 26 is present) can be visually recognized more clearly.

The wire diameter of the wire 54 of the coil 5 may be the same over the entire length of the coil 5, but the wire diameter of the wire 54 may be different between the distal end side and the proximal end side of the coil 5. For example, the wire diameter of the strand 54 may be smaller (or larger) on the distal end side of the coil 5 than on the proximal end side. Thereby, the softness | flexibility of the guide wire 1 in the front-end | tip part of the coil 5 can be improved more.

Further, the outer diameter of the coil 5 may be the same over the entire length of the coil 5, but the outer diameter of the coil 5 may be different between the distal end side and the proximal end side of the coil 5. For example, the outer diameter of the coil 5 may be smaller on the distal end side of the coil 5 than on the proximal end side. Thereby, the softness | flexibility of the guide wire 1 in the front-end | tip part of the coil 5 can be improved more.

In this embodiment, the adjacent strands 54 of the coil 5 are in contact with each other and are in a so-called dense winding state. These strands 54 generate a force (compression force) that pushes each other in the axial direction of the wire body 10 in a natural state. Here, the “natural state” refers to a state where no external force is applied. However, the present invention is not limited to this, and there may be a place where the adjacent strands 54 of the coil 5 are separated from each other.

As shown in FIG. 1, the coil 5 is fixed to the wire body 10 at two places (a plurality of places). That is, the distal end portion of the coil 5 is fixed to the distal end of the first wire 2 (the distal end of the constant outer diameter constant portion 26) by the fixing material 51, and the proximal end portion of the coil 5 is intermediate the first wire 2 by the fixing material 53. It is fixed to (around the boundary between the outer diameter constant portion 21 and the second taper portion 23). By fixing at such a location, the respective portions of the coil 5 can be reliably fixed to the wire body 10 without impairing the flexibility of the distal end portion (the portion where the coil 5 is present) of the guide wire 1. . In addition, the distal end side constant outer diameter portion 26 can be securely fixed to the coil 5, and the shape of the shaped distal end side outer diameter constant portion 26 can be appropriately maintained.

The fixing materials 51 and 53 are preferably made of solder (brazing material). The fixing materials 51 and 53 are not limited to solder and may be adhesives. Further, the method for fixing the coil 5 to the wire body 10 is not limited to the above-described fixing material, and for example, welding may be used. Moreover, in order to prevent damage to the inner wall of a body cavity such as a blood vessel, the distal end surface of the fixing material 51 is preferably rounded (see FIG. 1).

As shown in FIG. 1, the outer surface of the guide wire 1 is provided with a resin coating layer 8 covering the whole (or a part thereof). The resin coating layer 8 can be formed for various purposes. As an example, the operability of the guide wire 1 is reduced by reducing the friction (sliding resistance) of the guide wire 1 and improving the slidability. May be improved.

In order to reduce the friction (sliding resistance) of the guide wire 1, the resin coating layer 8 is preferably made of a material that can reduce friction as described below. Thereby, the frictional resistance (sliding resistance) with the inner wall of the catheter used together with the guide wire 1 is reduced, the slidability is improved, and the operability of the guide wire 1 in the catheter becomes better. Further, since the sliding resistance of the guide wire 1 is reduced, when the guide wire 1 is moved and / or rotated in the catheter, kinks (bending) or twisting of the guide wire 1, Twist can be prevented more reliably.

Examples of materials that can reduce such friction include polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyesters (PET, PBT, etc.), polyamides, polyimides, polyurethanes, polystyrenes, polycarbonates, silicone resins, fluorine resins ( PTFE, ETFE, etc.) or a composite material thereof.

Also, the resin coating layer 8 can be provided for the purpose of improving safety when the guide wire 1 is inserted into a blood vessel or the like. For this purpose, it is preferable that the resin coating layer 8 is made of a flexible material (soft material, elastic material).

Examples of such flexible materials include polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyester (PET, PBT, etc.), polyamide, polyimide, polyurethane, polystyrene, silicone resin, polyurethane elastomer, polyester elastomer, polyamide. Examples thereof include thermoplastic elastomers such as elastomers, various rubber materials such as latex rubber and silicone rubber, or composite materials in which two or more of these are combined.

In this embodiment, the constituent material of the resin coating layer 8 is different between the distal end side and the proximal end side with respect to the position in the middle of the second taper portion 23. Thereby, for example, the material of the portion covering the first wire 2 and the coil 5 of the resin coating layer 8 is made of the above-mentioned flexible material, and the material of the portion covering the second wire 4 of the resin coating layer 8 is formed. It can be made of a material that can reduce the friction.

Further, in the guide wire 1, the resin coating layer 8 may be entirely composed of the same material, or may be composed of three or more different constituent materials.

The resin coating layer 8 may be a single layer or a laminate of two or more layers (for example, an inner layer made of a material that is more flexible than an outer layer). For example, the portion of the resin coating layer 8 that covers the first wire 2 and the coil 5 can be a single layer, and the material of the portion of the resin coating layer 8 that covers the second wire 4 can be a laminate of two or more layers. . Moreover, the reverse may be sufficient.

A groove (not shown) may be formed on the outer peripheral surface of the resin coating layer 8. In particular, a pattern such as a linear shape, a curved shape, a ring shape, a spiral shape, a net shape, or the like is provided on a portion corresponding to at least the constant distal end outer diameter portion 26 (the outer peripheral portion of the constant distal end outer diameter portion 26). The groove is preferably formed. By forming such a groove, the flexibility of the distal end portion of the guide wire 1 is increased, the friction (sliding resistance) of the guide wire 1 is reduced, and the slidability can be further improved.

Moreover, it is preferable that a hydrophilic material is coated on the outer surface of at least the tip of the guide wire 1. As a result, the hydrophilic material is wetted to produce lubricity, the friction (sliding resistance) of the guide wire 1 is reduced, and the slidability is improved. Therefore, the operability of the guide wire 1 is improved.

Examples of hydrophilic materials include cellulose-based polymer materials, polyethylene oxide-based polymer materials, and maleic anhydride-based polymer materials (for example, maleic anhydride copolymers such as methyl vinyl ether-maleic anhydride copolymer). Acrylamide polymer substances (for example, polyacrylamide, block copolymer of polyglycidyl methacrylate-dimethylacrylamide (PGMA-DMAA)), water-soluble nylon, polyvinyl alcohol, polyvinylpyrrolidone and the like.

Such a hydrophilic material often exhibits lubricity by wetting (water absorption) and reduces frictional resistance (sliding resistance) with the inner wall of the catheter used together with the guide wire 1. Thereby, the slidability of the guide wire 1 is improved, and the operability of the guide wire 1 in the catheter becomes better.

As shown in FIGS. 1 and 2, the extension portion 3 is attached (connected) to the proximal end portion of the second wire 4. The extension part 3 has a distal end opening 31 and is configured by a tubular body whose base end is closed by a wall part 32. The guide wire 1 is in an assembled state in which the proximal end portion of the second wire 4 is inserted from the distal end opening 31 of the extension portion 3.

Further, as shown in FIGS. 2 (a) to 2 (c), the extension portion 3 has projecting portions 33, 34, and 35 projecting inward in the vicinity of the tip opening 31 on the inner peripheral portion thereof. . The protrusions 33, 34, and 35 are spaced apart from each other in this order from the tip side.

The protrusions 33, 34, and 35 are provided over the entire circumference of the extension 3. Further, the protrusions 33, 34, and 35 are semicircular when viewed in the longitudinal section of the extension portion 3, and their surfaces are rounded.

Further, a recess 36 is formed between the protrusion 33 and the protrusion 34, and a recess 37 is formed between the protrusion 34 and the protrusion 35. The concave portion 36 and the concave portion 37 are portions into which the convex portions 411 and 412 of the convex portion groups 41a to 41c of the second wire 4 enter and engage, respectively.

Such an extension portion 3 is configured to be movable in the longitudinal direction with respect to the second wire 4, and the guide wire 1 is shown in a shortened state shown in FIG. 2A and in FIG. 2B. The first extended state and the second extended state shown in FIG.

2A, in the shortened state, the convex portion 411 of the convex portion group 41a is engaged with the concave portion 36, and the convex portion 412 of the convex portion group 41a is engaged with the concave portion 37. In this state, the protrusion 411 of the protrusion group 41a is restricted from moving in the longitudinal direction of the guide wire 1 by the protrusion 33 and the protrusion 34, and the protrusion 412 of the protrusion group 41a is the protrusion 34 and the protrusion. The movement of the guide wire 1 in the longitudinal direction is restricted by the portion 35. For this reason, in the guide wire 1, a shortened state can be maintained.

Further, as shown in FIG. 2A, the base end portion of the second wire 4 is in contact with the wall portion 32 of the extension portion 3 in this shortened state. Thereby, it can prevent that the extension part 3 moves to a front end side with respect to the wire main body 10. FIG.

From the shortened state shown in FIG. 2A, when the extension portion 3 is pulled to the proximal end side with respect to the second wire 4, the protruding portion 34 gets over the protruding portion 412 of the protruding portion group 41a, and the protruding portion 33 becomes the protruding portion. The convex part 411 and the convex part 412 of the group 41a are overcome in order. Thereby, the extension part 3 can move to the proximal end side with respect to the second wire 4.

When the extension portion 3 is further pulled toward the proximal end side with respect to the second wire 4, as shown in FIG. 2 (b), the protrusion portion 35 moves over the protrusion portion 411 and the protrusion portion 412 of the protrusion group 41b in order and becomes a recess portion. 37, the projecting portion 34 gets over the convex portion 411 of the convex portion group 41 b and reaches the concave portion 36. Thereby, the guide wire 1 will be in a 1st extended state. In the first extended state, the convex portion 411 of the convex portion group 41 b is engaged with the concave portion 36, and the convex portion 412 of the convex portion group 41 b is engaged with the concave portion 37. In this state, the protrusion 411 of the protrusion group 41b is restricted from moving in the longitudinal direction of the guide wire 1 by the protrusion 33 and the protrusion 34, and the protrusion 412 of the protrusion group 41b is the protrusion 34 and the protrusion 35. Therefore, the movement of the guide wire 1 in the longitudinal direction is restricted. For this reason, the guide wire 1 can maintain the first extended state.

When the extension portion 3 is pulled toward the proximal end side with respect to the second wire 4 from the first extended state shown in FIG. 2B, the protruding portion 34 gets over the protruding portion 412 of the protruding portion group 41 b and the protruding portion 33. Gets over the convex portions 411, 412 of the convex portion group 41b in order. Thereby, the extension part 3 can move to the proximal end side with respect to the second wire 4.

When the extension portion 3 is further pulled toward the proximal end side with respect to the second wire 4, as shown in FIG. 2C, 35 sequentially passes over the convex portions 411 and 412 of the convex portion group 41c and reaches the concave portion 37. The protruding portion 34 gets over the protruding portion 411 of the protruding portion group 41 b and reaches the recessed portion 36. Thereby, the guide wire 1 will be in a 2nd extended state. In the second extended state, the convex portion 411 of the convex portion group 41 c is engaged with the concave portion 36, and the convex portion 412 of the convex portion group 41 c is engaged with the concave portion 37. In this state, the protrusion 411 of the protrusion group 41c is restricted from moving in the longitudinal direction of the guide wire 1 by the protrusion 33 and the protrusion 34, and the protrusion 412 of the protrusion group 41c is the protrusion 34 and the protrusion 35. Therefore, the movement of the guide wire 1 in the longitudinal direction is restricted. For this reason, the guide wire 1 can maintain the second extended state.

In this way, the engagement positions of the concave portion 36 and the concave portion 37 and the convex portion 411 and the convex portion 412 of the convex portion group 41a to the convex portion group 41c are changed according to the degree of tension (displacement) with respect to the extension portion 3. The total length of the guide wire 1 can be changed by the simple method. Therefore, it is possible to dramatically shorten the time required for the operation of changing the total length of the guide wire 1 during the procedure described later, and to extend the total length of the guide wire 1 quickly and smoothly compared to the conventional technique. .

Furthermore, in the conventional guide wire, the extension portion and the wire body are fixed by fitting. For this reason, when repeatedly used, the fitting strength tends to decrease, and the extension portion and the wire main body tend to be insufficiently fixed. On the other hand, in the guide wire 1, since the extension part 3 is connected to the wire body 10, even if it is repeatedly used, it is possible to prevent the extension operation from being adversely affected. Therefore, the guide wire 1 is excellent in durability.

Further, as shown in FIGS. 2A and 2B, the difference ΔL ₁ between the total length L ₁ of the guide wire 1 in the shortened state and the total length L ₂ in the first extended state is 10 to 1500 mm. It is preferably about 100 to 1000 mm. Further, as shown in FIG. 2 (b) and (c), the difference between the total length L ₂ of the guide wire 1 in the first extension state, the guide overall length L ₃ of the wire 1 in the second extended state ΔL ₂ is preferably 10 to 1500 mm, and more preferably about 100 to 1000 mm.

The constituent material of the extension 3 is not particularly limited. For example, various resin materials such as polyester, polyvinyl chloride, and urethane resin, and metal materials that are the same constituent materials as the wire body 10 are used. Can do.

In particular, since the extension portion 3 is formed of a hollow body, the rigidity tends to be low. However, when a metal material having the same constituent material as that of the wire body 10 is used, sufficient rigidity can be ensured. . Therefore, it is excellent in pushability, kink resistance, and torque transmission.

When a resin material is used, for example, the flexibility or rigidity can be adjusted by changing the average molecular weight (polymerization degree) of the constituent material of the extension 3 or the amount of plasticizer added (content). it can.

Examples of the plasticizer include phthalic acid diesters such as di-2-ethylhexyl phthalate (DEHP) and dinormaldecyl phthalate (DnDP), and adipine such as di-2-ethylhexyl adipate (DEHA). Acid diesters, trimellitic acid triesters, and the like can be used. Of these, di-2-ethylhexyl phthalate (DEHP), dinormaldecyl phthalate (DnDP), and the like are preferable.

In the above description, the protrusions 411 and 412 of the second wire 4 and the protrusions 33, 34, and 35 of the extension 3 are semicircular in the longitudinal section of the guide wire 1. The invention is not limited to this. The convex portion 411, the convex portion 412, and the projecting portions 33, 34, and 35 may have a prismatic shape in the longitudinal section of the guide wire 1, for example, and may have any shape such as a triangle. Further, in the longitudinal section of the guide wire 1, the convex portion 411, the convex portion 412, and the projecting portions 33, 34, and 35 can have different shapes on the distal end side and the proximal end side with respect to their top portions. In this case, when the extension part 3 is operated, the convex part 411, the convex part 412 and the projecting parts 33, 34, 35 can be easily ridden on one side, but can also be difficult to climb on the other side. Thereby, for example, even if the extension part 3 is gripped and the entire guide wire 1 is pushed into the living body, it is possible to prevent unintentional shortening.

Next, a method for using the guide wire 1 will be described.
First, as shown in FIG. 3, the guide wire 1 is inserted into the blood vessel 100 from the distal end side toward the lesioned portion 101 in the blood vessel 100. At the time of this insertion, the guide wire 1 is in a shortened state. Thereby, it can prevent that the full length of the guide wire 1 becomes uselessly long and operativity falls.

As shown in FIG. 3, when the guide wire 1 in the shortened state cannot be sufficiently inserted to the tip of the lesioned part 101, the extension part 3 is left while the wire body 10 is left in the living body as shown in FIG. 4. Is pulled proximally with respect to the wire body 10. As a result, the guide wire 1 is in the first extended state, and the tip can be sufficiently inserted to the tip of the lesioned part 101 as the total length becomes longer.

Further, in this embodiment and a second embodiment described later, when the distal end of the extension 3 enters the catheter (not shown) or the living body, the extension 3 is pulled toward the proximal side with respect to the wire body 10. Therefore, it is necessary to pull the tip of the extension part 3 before entering the catheter or the living body. In the third to twelfth embodiments, which will be described later, the extension 3 can be pulled even when the distal end of the extension 3 enters the catheter or the living body.

Then, the catheter is inserted into the living body so that the guide wire 1 is inserted through the catheter. During this insertion, as shown in FIG. 4, the guide length of the portion from the wire 1 of the living body surface protrudes outward when L ₄ is short, the proximal end portion of the guide wire 1 into the tip opening of the catheter (extension It becomes difficult to perform the operation of inserting 3).

In this case, as shown in FIG. 5, the extension portion 3 is further pulled toward the proximal end side with respect to the wire body 10. As a result, the guide wire 1 is in the second extended state, and the length of the portion of the guide wire 1 protruding outward from the living body surface is set to a length L ₅ longer than the length L ₄ shown in FIG. be able to. Therefore, in the guide wire 1, the operation of inserting the proximal end portion (extension portion 3) of the guide wire 1 into the distal end opening of the catheter can be easily performed by the length of the entire length.

Then, catheter treatment is performed by inserting the distal end of the catheter to the vicinity of the lesion 101. As this catheter treatment, for example, a drug is directly administered to an affected part (lesion) via a catheter, or a lesion part 101 in a blood vessel is pushed using a catheter attached to a tip of a balloon that is expanded by pressurization. Examples of the treatment include opening and spreading, and treatment using a catheter having a cutter attached to the distal end to scrape and open the lesion 101.

Thus, in the guide wire 1, the total length of the guide wire 1 can be changed stepwise (three steps in this embodiment) by the extension portion 3. Thereby, as above-mentioned, the guide wire 1 can be adjusted to the length suitable for performing the procedure as needed. In particular, the present invention can be said to be very useful when exchanging a catheter while the guide wire 1 is left in the living body.

Second Embodiment
FIG. 6: is a longitudinal cross-sectional view which shows the extension part with which 2nd Embodiment of the guide wire of this invention is equipped with (a) and (b).

Hereinafter, the second embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the first embodiment except that the configuration of the extension is different.

6A and 6B, in the guide wire 1A, a male screw portion 42 is formed from the middle of the second wire 4 to the base end. The male screw portion 42 is configured by a spiral rib provided on the outer peripheral portion of the second wire 4.

Further, the extension portion 3A has a female screw portion 38 that is provided on the inner peripheral portion thereof and that is screwed with the male screw portion 42 of the second wire 4. The female screw portion 38 is formed by a spiral groove.

When the extension 3A is rotated in the direction of the arrow in FIG. 6A from the shortened state shown in FIG. 6A, as shown in FIG. 6B, the extension 3A is It moves to the proximal end side with respect to the wire body 10. Thereby, the full length of the guide wire 1A becomes long and can be made into an extended state.

6B can be returned to the shortened state shown in FIG. 6A by rotating the extension 3A with respect to the wire body 10 in the direction of the arrow in FIG. 6A from the extended state shown in FIG. .

The same effect as that of the first embodiment can also be obtained by the second embodiment. Furthermore, according to the second embodiment, the length of the guide wire 1A can be adjusted more finely than in the first embodiment, that is, in multiple stages. Therefore, the guide wire 1A is very advantageous in a procedure that requires fine adjustment of the length.

<Third Embodiment>
FIGS. 7A to 7C are longitudinal sectional views showing extensions provided in the third embodiment of the guide wire of the present invention.

Hereinafter, the third embodiment of the guide wire according to the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the first embodiment except that the configuration of the extension is different.

As shown in FIGS. 7A to 7C, in the guide wire 1B, the second wire 4 has a tubular portion 43 at its proximal end. The tubular portion 43 has a proximal end opening 431 that opens to the proximal end of the guide wire 1B. Further, the tubular portion 43 has a pair of projecting portions 432 and 433 provided on the inner peripheral portion of the base end thereof. The pair of protrusions 432 and 433 are provided so as to be shifted from each other in the longitudinal direction of the guide wire 1. In addition, a recess 434 is formed between the protrusion 432 and the protrusion 433.

As shown in FIGS. 7A to 7C, in the guide wire 1B, the extension 3B is composed of a rod-like long body inserted into the tubular portion 43 from the proximal end opening 431. By making the extension portion 3B a solid body, although depending on the constituent material, so-called “strain” becomes stronger and the operability in the extended state is enhanced.

Further, the extension portion 3B is provided in the middle of the longitudinal direction, and has projecting portion groups 39a, 39b, and 39c that project outward from the outer peripheral portion. The protruding portion groups 39a to 39c are provided apart from each other in the longitudinal direction of the extension portion 3B. The protruding portion groups 39a to 39c are arranged in this order from the tip side. Each of the protruding portion groups 39a to 39c includes three protruding portions 391.

In the shortened state shown in FIG. 7A, the protruding portion group 39c enters the recess 434, and the shortened state is maintained. By pulling the extension portion 3B toward the proximal end side with respect to the wire body 10 from the state shown in FIG. 7A, the protruding portion group 39b can enter the recess portion 434 to be in the first extension state. When the extension portion 3B is further pulled to the proximal end side with respect to the wire body 10 from the first extension state shown in FIG. 7B, the protruding portion group 39a enters the recess portion 434 to be in the second extension state. .

For such a protruding portion 391, for example, an elastic rubber material or the like can be suitably used.

As mentioned above, according to 3rd Embodiment, there can exist an effect similar to 1st Embodiment. Furthermore, since the outer diameter of the extension 3B can be made smaller than the maximum outer diameter of the wire body 10 (second wire 4), the maximum outer diameter when viewed from the entire guide wire 1B is greater than or equal to the wire body 10. It can prevent becoming thick. Therefore, for example, even a medical device having a relatively small inner diameter such as a microcatheter can insert the guide wire 1B.

<Fourth embodiment>
FIGS. 8A to 8C are longitudinal sectional views showing extensions provided in the fourth embodiment of the guide wire of the present invention.

Hereinafter, the fourth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the third embodiment except that the configuration of the extension is different.

As shown in FIGS. 8A to 8C, the guide wire 1C is formed with projecting portions 44a, 44b, and 44c that project from the inner peripheral portion of the tubular portion 43. These protrusions 44a to 44c are provided so as to be displaced from each other in the longitudinal direction of the guide wire 1. Further, each of the projecting portions 44a to 44c is constituted by a pleated small protrusion having elasticity.

Further, the second wire 4 has a proximal diameter inner peripheral portion thereof, that is, a reduced diameter portion (detachment preventing portion) 435 in which the inner diameter in the vicinity of the proximal end opening 431 is sharply reduced.

Moreover, as shown to Fig.8 (a), the extension part 3C has the enlarged diameter part 31c which the front-end | tip part expanded. As shown in FIG. 8A, the enlarged diameter portion 31c is engaged with the protruding portion 44a in the shortened state. In this engaged state, the small diameter protrusion 31a is fixed so that the small protrusion 31c is crushed by the large diameter portion 31c. Thereby, the shortened state is maintained.

Further, in the first extended state shown in FIG. 8B, the enlarged diameter portion 31c engages with the protruding portion 44b as described above. Thereby, the first extended state is maintained. Moreover, in the 2nd extended state shown in FIG.8 (c), the enlarged diameter part 31c engages with the protrusion part 44c. Thereby, the second extended state is maintained.

Further, when the extension portion 3C is further pulled to the proximal end side from the second extended state shown in FIG. 8C, the enlarged diameter portion 31c engages with the protruding portion 44c. Thereby, the second extended state is maintained.

8C, each diameter portion 31c abuts on the reduced diameter portion 435, and the extension portion 3C further moves to the proximal end side and is detached from the tubular portion 43. Can be prevented.

<Fifth Embodiment>
9 (a) to 9 (c) are longitudinal sectional views showing extensions provided in the fifth embodiment of the guide wire of the present invention.

Hereinafter, the fifth embodiment of the guide wire according to the present invention will be described with reference to this figure. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the fourth embodiment except that the configuration of the extension is different.

As shown in FIGS. 9A to 9C, in the guide wire 1D, a female screw portion 430 is provided on the inner peripheral portion of the tubular portion 43. The female screw portion 430 is configured by a spiral groove.

Further, the extension 3D has a male screw portion 31d in the vicinity of the tip thereof. The male screw portion 31d is screwed with the female screw portion 430.

In such a guide wire 1D, as shown in FIG. 9 (a), when the extension 3D is rotated with respect to the wire body 10, the guide wire 1D is moved as shown in FIGS. 9 (b) and 9 (c). The length can be changed. In addition, the guide wire 1D can change the entire length steplessly, that is, continuously, and is more convenient.

<Sixth Embodiment>
10 (a) to 10 (c) are longitudinal sectional views showing an extension portion provided in the sixth embodiment of the guide wire of the present invention.

Hereinafter, the sixth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the fifth embodiment except that the configuration of the extension is different.

As shown in FIGS. 10 (a) to 10 (c), the second wire 4 of the guide wire 1E communicates with the lumen portion 44 and includes a first groove 441 extending along its longitudinal direction, A second groove 442, a third groove 443, and a fourth groove 444 communicating with the first groove 441.

The tip of the first groove 441 is the same as the position of the tip of the lumen 44. Further, the proximal end of the first groove 441 is located on the distal end side with respect to the proximal end opening 431 of the tubular portion 43. That is, the first groove 441 is not open to the proximal end opening 431.

The second groove 442 is located at the tip of the first groove 441 and extends in the circumferential direction of the second wire 4 over approximately ¼ circumference.

The third groove 443 is located in the middle of the first groove 441 and extends in the circumferential direction of the second wire 4 over approximately ¼ circumference.

The fourth groove 444 is located at the base end of the first groove 441 and extends in the circumferential direction of the second wire 4 over approximately ¼ circumference.

As shown in FIGS. 10A to 10C, a protrusion 31e protruding in the radial direction is provided at the tip of the extension 3E of the guide wire 1E.

In the shortened state shown in FIG. 10A, the protrusion 31e is located in the second groove 442. At this time, the protrusion 31e is in a state in which the movement of the guide wire 1E in the longitudinal direction is restricted by the side surface of the second groove 442. Thereby, the shortened state can be maintained.

When the extension 3E is rotated in the direction indicated by the arrow in FIG. 10A from the shortened state shown in FIG. 10A, the protrusion 31e moves in the second groove 442, not shown, to the first It moves to a position communicating with the groove 441. By pulling the extension 3E toward the base end from this state, the extension 3e can move to the base end, and the entire length of the guide wire 1E can be extended.

Then, when the protrusion 31e moves to the portion of the first groove 441 that communicates with the third groove 443, the extension portion 3E rotates in the opposite direction. Thereby, the protrusion 31e can move in the third groove 443 to be in the first extended state shown in FIG. At this time, the protrusion 31e is in a state in which the movement of the guide wire 1E in the longitudinal direction is restricted by the side surface of the third groove 443. As a result, the second extended state can be maintained.

When the extension 3E is rotated in the direction of the arrow in FIG. 10B from the first extended state shown in FIG. 10B, the protrusion 31e moves in the third groove 443, although not shown. The first groove 441 moves to a position where it communicates. By pulling the extension portion 3E to the proximal end side from this state, the extension portion 3E can move to the proximal end side, and the entire length of the guide wire 1E can be further extended.

Then, when the protrusion 31e moves to a portion of the first groove 441 that communicates with the fourth groove 444, the extension portion 3E is rotated in the direction of the arrow in FIG. Thereby, the protrusion 31e can move in the fourth groove 444 to be in the first extended state shown in FIG. At this time, the protrusion 31e is in a state in which the movement of the guide wire 1E in the longitudinal direction is restricted by the side surface of the fourth groove 444. Thereby, while being able to maintain a 3rd extension state, it can also prevent that the extension part 3E remove | deviates from the wire main body 10. FIG.

According to this embodiment as described above, the shortened state, the first extended state, and the second extended state can be switched by a simple method of rotating the extension portion 3E. That is, unless the extension portion 3E is rotated, it is possible to reliably prevent the shortened state, the first extended state, and the second extended state from being switched unintentionally.

<Seventh embodiment>
11 (a) to 11 (c) are longitudinal sectional views showing extensions provided in the seventh embodiment of the guide wire of the present invention.

Hereinafter, the seventh embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the sixth embodiment except that the configuration of the extension is different.

As shown in FIGS. 11 (a) to 11 (c), in the guide wire 1F, the second wire 4 has a recess 45 provided at the tip of the lumen portion 41 and further recessed at the tip side. Yes. In the recess 45, a spring (biasing member) 31f is installed in a compressed state. For this reason, the spring 31f will press the extension part 3E toward the base end side.

When it is desired to extend the entire length of the guide wire 1F, the extension 3F is rotated from the shortened state shown in FIG. 11A to release the engagement between the protrusion 31e and the second groove 442, and the protrusion 31e is The groove 441 is moved to a movable position. At this time, the extension part 3F can move to the base end side by the biasing force of the spring 31f. Then, when the protrusion 31e has moved to the position of the third groove 443, the first extended state can be obtained by rotating in the arrow direction in FIG.

When changing from the shortened state to the second extended state, when the protrusion 31e moves to the position of the fourth groove 444, it is rotated in the direction of the arrow in FIG. Needless to say, the second extended state can be easily changed from the first extended state.

As described above, according to the present embodiment, by providing the restriction of the biasing force of the spring 31f and the extension part 3F as a restriction part capable of releasing the restriction, the shortened state and the first extended state can be easily and reliably provided. And the second extended state can be switched. Further, since the spring 31f functions as an auxiliary portion that assists the extension of the guide wire 1F by the urging force, the operation can be easily performed.

<Eighth Embodiment>
12 (a) and 12 (b) are longitudinal sectional views showing extensions provided in the eighth embodiment of the guide wire of the present invention.

Hereinafter, the eighth embodiment of the guide wire according to the present invention will be described with reference to this drawing, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the sixth embodiment except that the configuration of the extension is different.

12 (a) and 12 (b), in the guide wire 1G, the second wire 4 has a recess 46 that opens to the base end and in which a coil spring 32g described later is installed. The second wire 4 has a cylindrical portion 47 that protrudes in a cylindrical shape from the proximal end surface toward the proximal end side. A male threaded portion 471 formed of a spiral rib is formed on the outer peripheral portion of the tubular portion 47.

Also, as shown in FIGS. 12A and 12B, the extension 3G has a rod-like part (linear part) 31g and a coil spring 32g that can be expanded and contracted.

The rod-shaped part 31g has a recess 311 that is open at the tip and in which the coil spring 32g is installed. Moreover, the rod-shaped part 31g has the cylindrical part 312 which protruded cylindrically toward the front end side. On the inner peripheral portion of the cylindrical portion 312, a female screw portion 313 configured by a spiral groove and screwed with the male screw portion 471 is formed.

The coil spring 32g has a distal end fixed to the bottom of the recess 46 of the second wire 4, and a proximal end fixed to (connected to) the bottom of the recess 311 of the rod-shaped portion 31g.

As shown in FIG. 12 (a), in the guide wire 1G, the coil spring 32g is in a compressed state when the male screw portion 471 and the female screw portion 313 are screwed together. From this state, when the rod-shaped part 31g is rotated with respect to the second wire 4 and the screwing of the male screw part 471 and the female screw part 313 is released, the biasing force of the coil spring 32g is shown in FIG. As a result, the rod-shaped portion 31g moves to the proximal end side. Thereby, guide wire 1G can be made into an extended state.

According to such an eighth embodiment, the rod-like portion 31g is rotated with respect to the second wire 4 to be extended by a simple method of releasing the screwing between the male screw portion 471 and the female screw portion 313. be able to.

In order to change from the extended state shown in FIG. 12 (b) to the shortened state shown in FIG. 12 (a), the rod-shaped portion 31g is brought close to the second wire 4 against the urging force of the coil spring 32g, and the male screw The part 471 and the female screw part 313 are screwed together.

<Ninth Embodiment>
FIG. 13: is a longitudinal cross-sectional view which shows the extension part with which 9th Embodiment of the guide wire of this invention is equipped with (a) and (b).

Hereinafter, the ninth embodiment of the guide wire according to the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the third embodiment except that the configuration of the extension is different.

As shown in FIGS. 13A and 13B, in the guide wire 1H, three protrusions 436, 437, and 438 provided at different positions on the inner peripheral portion of the tubular portion 43 are formed. Each of the protrusions 436, 437, and 438 extends in the circumferential direction and has a ring shape. The protrusion 436 is located near the tip of the tubular portion 43. The protrusion 437 is provided slightly on the tip side with respect to the base end opening 431. The protrusion 438 is located at the edge of the base end opening 431. Further, the protrusion 437 and the protrusion 438 are provided close to each other, and a recess 439 is formed between them.

The extension 3H has a double tube structure composed of an outer tube 31h and an inner tube 32h.
The outer tube 31h is inserted into the tubular portion 43 and is movable along the longitudinal direction of the guide wire 1H. Further, a flange 314 protruding in a ring shape is provided on the outer peripheral portion of the tip of the outer tube 31h.

The outer tube 31h has projections 315, 316, and 317 that are provided at different positions on the inner peripheral portion and project in a ring shape. The protrusion 315 is located near the tip of the inner periphery. The protrusion 316 is provided slightly on the distal end side with respect to the proximal end opening of the outer tube 31h. The protrusion 317 is located at the edge of the proximal end opening of the outer tube 31h. Further, the protrusion 315 and the protrusion 316 are provided close to each other, and a recess 318 is formed between them.

The inner tube 32h is inserted into the outer tube 31h, and is provided so as to be movable in the outer tube 31h along the longitudinal direction of the guide wire 1H. Further, a flange 321 protruding in a ring shape is provided on the outer peripheral portion of the inner tube 32h.

In such a guide wire 1H, in a shortened state as shown in FIG. 13A, the outer tube 31h is accommodated in the tubular portion 43, and the inner tube 32h is accommodated in the outer tube 31h. In this shortened state, the movement of the flange 314 of the outer tube 31h is restricted by the protrusion 436 of the tubular portion 43, and the movement of the flange 321 of the inner tube 32h is restricted by the protrusion 315 of the outer tube 31h. Thereby, the shortened state can be maintained.

In this shortened state, the proximal end portion of the outer tube 31h protrudes from the tubular portion 43, and the inner tube 32h protrudes from the proximal end portion of the outer tube 31h.

When the proximal end portion of the inner tube 32h is gripped and pulled toward the proximal end from the shortened state, the flange 321 of the inner tube 32h gets over the protrusion 315. When pulled further, the flange 321 goes over the protrusion 316 and reaches the recess 318. Thereby, it can be in the 1st extended state (not shown).

Further, when the inner tube 32h is pulled to the proximal end side from the first extended state, the pulling force of the inner tube 32h is transmitted to the outer tube 31h. As a result, the flange 314 of the outer tube 31 h gets over the protrusion 436 of the tubular portion 43. When pulled further, the flange 314 of the outer tube 31 h gets over the protrusion 437 of the tubular portion 43 and reaches the recess 439. Thereby, it can be set as the 2nd extended state.

In this second extended state, the inner tube 32h is prevented from being detached from the outer tube 31h by the engagement between the flange 321 and the protrusion 317 of the outer tube 31h.

According to the ninth embodiment, the shortened state, the first extended state, and the second extended state can be switched by a simple operation of pulling the inner tube 32h.

In addition, when changing from the shortened state to the first extended state, the proximal end portion of the outer tube 31h may be gripped and pulled.

<Tenth Embodiment>
14 (a) and 14 (b) are longitudinal sectional views showing extensions provided in the tenth embodiment of the guide wire of the present invention.

Hereinafter, the tenth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the first embodiment except that the configuration of the extension is different.

As shown in FIGS. 14A and 14B, the second wire 4 has a pair of extending portions 48 extending from the base end portion to the base end side. Further, the base end portion of each extending portion 48 is connected by a rotation support portion 49.

The extension portion 3J has a pair of rotation rods 31j, a rotation support portion 32j connected to each rotation rod 31j, and an operation rod 33j.

The pair of rotation rods 31j are rotatably supported by the rotation support portion 49. In addition, each rotating bar 31j is disposed between the extending portions 48.

The operating rod 33j is rotatably supported by the rotation support portion 32j. The operation bar 33j is located between the rotating bars 31j.

In the shortened state shown in FIG. 14, the pair of rotating rods 31j and the operating rod 33j are in a folded state. From this folded state, the operating rod 33j is gripped, and the turning support portion 32j is pulled to the base end side while being lifted to the front side in the figure, for example, so that the pulling force is paired via the turning support portion 32j. The rotation rod 31j is rotated about the rotation support portion 49.

This operation is performed from the state shown in FIG. 14 (a) until the rotating rod 31j rotates approximately 180 °, so that it can be expanded and extended as shown in FIG. 14 (b).

According to the present embodiment, since the extension portion 3J can be deformed from the folded state to the expanded state, the extension portion 3J is brought into the extended state by a simple method of rotating the operation bar 33j. be able to. In addition, the length of the guide wire 1J can be adjusted in multiple stages by adjusting the site to be deployed.

By appropriately setting a tolerance between the rotation support portion 49 and the hole of the rotation rod 31j into which the rotation support portion 49 is inserted, for example, by making a so-called “intermediate fit”, the rotation rod 31j Unintentional rotation can be prevented. The same applies to the rotation support portion 32j and the operation rod 33j.

<Eleventh embodiment>
FIGS. 15A to 15C are longitudinal sectional views showing extensions provided in the eleventh embodiment of the guide wire of the present invention.

Hereinafter, the eleventh embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the tenth embodiment except that the configuration of the extension is different.

As shown in FIG. 15A, in the guide wire 1K, the second wire 4 has a semicircular portion 40 having a semicircular cross-sectional shape at the base end portion.

Further, the extension part 3K has a first semicircular part 31k and a second semicircular part 32k having a semicircular cross-sectional shape. The first semicircular part 31k is connected to the semicircular part 40 via a rotation support part 33k. The second semicircular part 32k is connected to the first semicircular part 31k via a rotation support part 34k.

In such a shortened state as shown in FIG. 15A, such an extension 3K has a flat surface 311k of the first semicircle 31k and a second semicircle 32k on the flat surface 401 of the semicircle 40. The flat surface 321k is in contact with the guide wire 1K, and the base end portion of the guide wire 1K is viewed as a round bar. Thus, in the shortened state, the extension portion 3K is in a folded state.

When the first semicircular portion 31k is rotated about the rotation support portion 33k from the shortened state, the guide wire 1K is in the first extended state as shown in FIG. In this first extended state, the end portion 312k of the first semicircular portion 31k and the base end portion 402 of the semicircular portion 40 abut, and further rotation of the first semicircular portion 31k is restricted. ing. Thereby, the first extended state can be maintained.

When the second semicircular portion 32k is rotated around the rotation support portion 34k from the first extended state, as shown in FIG. 15C, the extended portion 3K is in an unfolded state, and the second It becomes an extended state. In the second extended state, the end portion 313k of the first semicircular portion 31k and the end portion 322k of the second semicircular portion 32k abut, and the second semicircular portion 32k is further rotated. It is regulated. As a result, the second extended state can be maintained.

According to the eleventh embodiment, the shortened state, the first extended state, and the second extended state can be obtained by a simple method of folding or unfolding the extension portion 3K connected to the second wire 4. Can be switched.

<Twelfth embodiment>
FIG. 16: is a longitudinal cross-sectional view which shows the extension part with which 12th Embodiment of (a) and (b) is equipped with the guide wire of this invention.

Hereinafter, the twelfth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

The guide wire of this embodiment is substantially the same as the sixth embodiment except that the configuration of the extension is different.

As shown in FIGS. 16A and 16B, in the guide wire 1L, a relaxing portion 31L that relaxes the step between the outer periphery of the second wire 4 and the outer periphery of the extension portion 3L is provided on the outer periphery of the extension portion 3L. It has been. Hereinafter, the relaxation unit 31L will be described.

The relaxation portion 31L has an umbrella shape having a large number of umbrella bones 311L and a rotation support portion 312L that rotatably supports the umbrella bone 311L. Further, the rotation support portion 312L has a biasing force that biases the umbrella bone 311L toward the radial direction of the extension portion 3L.

In the shortened state shown in FIG. 16 (a), the relaxing portion 31L is located in the tubular portion 43 in a state where each umbrella bone 311L is folded, that is, in a state where it is laid down along the longitudinal direction of the extending portion 3L. ing. In this state, the opening of each umbrella bone 311 </ b> L is restricted by the inner peripheral portion of the tubular portion 43.

Also, as shown in FIG. 16 (b), when the extension portion 3L is pulled to the proximal end side from the shortened state to the first extended state, the relaxing portion 31L is exposed. As a result, the restriction of each umbrella bone 311L by the inner peripheral portion of the tubular portion 43 is released, and each umbrella bone 311L is rotated and opened by the urging force of the rotation support portion 312L. In this open state, the tip of each umbrella bone 311L is located at the edge of the outer periphery of the proximal end of the tubular portion 43. Thereby, it can be set as the state by which each umbrella bone | frame 311L was constructed in the part of the level | step difference with the outer periphery of the extension part 3L, and the outer periphery of the 2nd wire 4, and the outer periphery of the extension part 3L. Therefore, the step between the outer periphery of the second wire 4 and the outer periphery of the extension 3L can be reduced. As a result, for example, when the guide wire 1L is inserted through the catheter (not shown) from the proximal end side, it is possible to prevent a step from being caught on the inner peripheral portion of the catheter. Therefore, the procedure can be performed smoothly and the inner peripheral portion of the catheter can be prevented from being damaged.

It should be noted that each umbrella bone 311L is closed against the extension portion 3L against the urging force of the rotation support portion 312L, and the extension portion 3L is pushed into the distal end side as it is to shorten the extension state. It can be.

As mentioned above, although the guide wire of this invention was demonstrated about embodiment of illustration, this invention is not limited to this, Each part which comprises a guide wire is a thing of arbitrary structures which can exhibit the same function. Can be substituted. Moreover, arbitrary components may be added.

Moreover, you may combine each embodiment suitably.
Further, in the embodiments in which the length can be adjusted stepwise, the length can be adjusted in three steps, but the present invention is not limited to this. There may be four or more stages.

In each of the above embodiments, a marker serving as a notification unit indicating the degree of extension may be attached to the outer peripheral portion of the extension portion. In particular, when the color or the like of this marker is different at each extension stage, it is possible to easily recognize how much the marker is currently extended by visual recognition. Further, the notification unit may be a memory.

In each of the above embodiments, a fixing member that fixes the wire body may be used when the extended state is set in the middle of the procedure.

The extension may have a bellows-like portion.
Moreover, the lock part may be comprised with elastic bodies, such as rubber | gum, for example.

In the twelfth embodiment, the relaxation portion is provided on the outer peripheral portion of the extension portion. However, the invention is not limited to this, and the relaxation portion may be provided at the proximal end portion of the wire body. Good. In this case, for example, the relaxation portion can be configured by a tapered portion in which the outer diameter of the proximal end portion of the wire main body gradually decreases toward the proximal end side.

The guide wire of the present invention is a guide wire having a long and flexible wire body, which is connected to a proximal end portion of the wire body and is displaced to the proximal end side with respect to the wire body. By doing so, it is provided with the extension part used as the extension state which extends the full length of the said guide wire. Therefore, the guide wire can be extended by a simple operation. Therefore, as compared with the conventional technique, the time required for the operation to be extended in the middle of the procedure can be remarkably shortened, and the length of the guide wire can be extended quickly and smoothly.

1, 1A, 1B, 1C, 1D, 1E, 1F, 1G, 1H, 1J, 1K, 1L ... guide wire 2 ... first wire 21 ... outer diameter constant portion 22 ... first taper portion 23 ... 2nd taper part 24 ...... large diameter part 26 ...... tip side outer diameter constant part 3, 3A, 3B, 3C, 3D, 3E, 3F, 3G, 3H, 3J, 3K, 3L. Opening 31c ...... Expanded diameter part 31d ...... Male thread part 31e ...... Protrusion 31f ...... Spring 31g ...... Bar-shaped part 31h ...... Outer tube 31j ...... Rotating bar 31k ...... First semicircular part 31L ...... Relaxation Portion 311 …… Recess 311k …… Flat surface 311L …… Umbrella 312 …… Tubular portion 312k …… End 312L …… Rotation support 313 …… Female thread 313k …… Base end 314 …… Flange 315 ... Protrusions 316 ... Protrusions 317 ... Protrusions 318 ... Concavities 32 ... Walls 32g ... Coil spring 32h ... Inner tube 32j ... Rotating support part 32k ... Second semicircular part 321 ... Flange 321k ... Flat surface 322k ... Base end part 33 ... Projection part 33j ... Operating rod 33k ... ... Rotation support portion 34... Projection portion 34 k... Rotation support portion 35... Projection portion 36. ... projecting part group 391 ... projecting part 4 ... second wire 40 ... semicircular part 401 ... flat surface 402 ... proximal end part 41 ... lumen part 41a ... convex part group 41b ... convex part group 41c ...... Projection section 411 ...... Projection section 412 ...... Projection section 42 ... Male thread section 43 ... Tubular section 430 ... Female thread section 431 ... Base end opening 432 ... Projection section 433 ... Projection section 434 ... Recess 435 ... Reduced diameter part 436 ... Protrusion 437 ... Protrusion 438 ... Protrusion 439 ... Recess 44... Lumen 44 a... Projection 44 b... Projection 44 c... Projection 441... First groove 442 ... Second groove 443 ... Third groove 444. ...... Concave 46 ...... Concave 47 ...... Cylindrical part 471 ...... Male threaded part 48 ...... Extended part 49 ...... Rotating support part 5 ...... Coil 50 ...... Gap 51 54 ...... wire 6 ...... junction 8 ...... resin coating layer 10 ...... wire body 100 ...... vascular 101 ...... lesion _{L 1} ...... overall length _{L 2} ...... total length _{L 3} ...... overall length _{L 4} ...... length L ₅ ...... Length

Claims (11)

A guide wire having an elongated shape and having a flexible wire body,
A guide wire comprising an extension portion connected to a base end portion of the wire main body and being extended to extend the entire length of the guide wire by being displaced toward the base end side with respect to the wire main body. The guide wire according to claim 1, wherein the extension portion is capable of adjusting a degree of the extension state. The guide wire according to claim 1 or 2, wherein one of the wire body and the extension is inserted into the other. The guide wire according to any one of claims 1 to 3, further comprising a lock portion that maintains the extended state. The said lock | rock part has a convex part provided in one of the said wire main body and the said extension part, and a recessed part provided in the other and the said convex part engages. Guide wire. The wire body and the extension are screwed together,
The guide wire according to any one of claims 1 to 5, wherein the extension portion is in the extended state by being rotated around the axis of the wire main body with respect to the wire main body. The guide wire according to any one of claims 1 to 5, wherein the extension portion is brought into the extended state by being pulled toward a proximal end side with respect to the wire body. The extension portion has a multi-tube structure having at least an inner tube and an outer tube,
The guide wire according to claim 7, wherein the inner tube and the outer tube are relatively movable along a longitudinal direction of the wire body. The guide wire according to claim 1 or 2, wherein the extension portion is formed of a foldable member and is deformable from a folded state to an unfolded state. A biasing portion that biases the extension portion toward the proximal direction;
The guide wire according to any one of claims 1 to 9, further comprising a restriction of a biasing force of the biasing part with respect to the extension part and a restriction part capable of releasing the restriction. The guide wire according to any one of claims 1 to 10, further comprising a detachment preventing portion that prevents the extension portion from detaching from the wire body in the extended state.

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