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WO2016148434A1 - Composition cosmétique en émulsion ayant un système tampon de ph - Google Patents

Composition cosmétique en émulsion ayant un système tampon de ph Download PDF

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Publication number
WO2016148434A1
WO2016148434A1 PCT/KR2016/002341 KR2016002341W WO2016148434A1 WO 2016148434 A1 WO2016148434 A1 WO 2016148434A1 KR 2016002341 W KR2016002341 W KR 2016002341W WO 2016148434 A1 WO2016148434 A1 WO 2016148434A1
Authority
WO
WIPO (PCT)
Prior art keywords
acid
cosmetic composition
skin
hydroxyethyl
buffer system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2016/002341
Other languages
English (en)
Korean (ko)
Inventor
나철희
원보미
한종섭
박선규
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LG H&H Co Ltd
Original Assignee
LG Household and Health Care Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LG Household and Health Care Ltd filed Critical LG Household and Health Care Ltd
Priority to HK18103801.3A priority Critical patent/HK1244226B/zh
Priority to CN201680015173.8A priority patent/CN107427429B/zh
Publication of WO2016148434A1 publication Critical patent/WO2016148434A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • the present invention relates to an emulsified cosmetic composition having a pH buffer system.
  • the skin pH is weakly acidic, and the slightly acidic skin pH is associated with the activity of enzymes that maintain normal skin function such as serine protease and beta-glucocerebrosidase. There is this.
  • acne, atopy, and other troubled skin can be seen that the skin pH is higher than normal.
  • treatment of low pH substances on atopic and aged skin can restore the skin barrier and normalize the skin (Journal of Investigative Dermatology, 2847-2856, 127, 2007, Journal of Investigative Dermatology, 1824-1835, 129, 2009).
  • the stratum corneum functions to protect the skin from physical and chemical factors.
  • the skin can be kept clean and clear through turn over, which leads to the continuous production of skin cells and exfoliation in the stratum corneum.
  • Organic acids that promote exfoliation may include alpha hydroxy acids, beta hydroxy acids, polyhydroxy acids, and the like.
  • An object of the present invention is to provide an emulsified cosmetic composition having a low pH irritation caused by an organic acid and having a pH buffer system that can continuously alleviate skin pH changes caused by internal / external causes.
  • the present invention provides an emulsion cosmetic composition having a pH buffer system.
  • the pH buffer system is characterized by including a buffer solution containing an acid.
  • the present invention provides a cosmetic composition
  • a cosmetic composition comprising a buffer solution containing an acid and having a pH of 3 to 5.
  • the present invention includes a buffer solution containing an acid (acid), and provides a cosmetic composition for skin moisturizing and skin pH change alleviation having a pH of 3 to 5.
  • Cosmetic composition having a pH buffer system according to the present invention is less irritation by the organic acid, it can continuously alleviate the skin pH change due to internal and external causes, aging, acne and atopy by improving the exfoliation and skin barrier It can remarkably improve conditions, such as a troubled skin included.
  • the present invention provides an emulsion cosmetic composition having a pH buffer system.
  • the pH buffer system is characterized by including a buffer solution containing an acid.
  • the present invention provides an emulsion cosmetic composition
  • the emulsion cosmetic composition of the present invention is an emulsion which is a mixture of two or more liquids that do not fuse well, the type is not particularly limited.
  • the emulsion cosmetic composition of the present invention may be of oil in water (O / W) or water in oil (W / O) type.
  • it may be a multiple emulsion type such as water in oil in water (W / O / W) or oil in water in oil (O / W / O).
  • the emulsion cosmetic composition of the present invention may be oil-in-water.
  • Oil-in-water emulsion cosmetic composition is a form in which an oil phase consisting of oil and wax is dispersed in an aqueous phase composed of purified water, polyol, thickener, etc. by forming an emulsion structure by surfactant molecules having both hydrophilicity and lipophilic properties in the molecule. It is superior in moisturizing sustainability and skin suppleness compared to solubilized formulations, which is advantageous for the continuous improvement of troubled skin including atopy.
  • the buffer solution refers to a solution in which the pH of the solution is kept constant by maintaining a constant hydrogen ion concentration without being greatly affected by addition of some acid or base from the outside.
  • the buffer solution of the present invention contains an acid so that the pH of the entire cosmetic composition can be maintained at 3-5.
  • the pH range means pH when measured by the pH test method of the cosmetic test method
  • the cosmetic composition of the present invention is characterized in that the pH is 3 to 5. If the cosmetic composition is less than pH 3 may cause skin irritation, and when the pH is greater than 5, the effect of alleviating the skin pH change is weak.
  • the acid may be included in 0.1 to 3.0 parts by weight relative to 100 parts by weight of the total composition.
  • the pH of the composition can be continuously maintained at pH 3 to 5 without irritation to the skin.
  • the buffer solution may include an organic acid and its base, or may include an organic acid and a pH adjuster.
  • the pH can be kept constant.
  • the organic acid is, but is not limited to, one from the group consisting of citric acid, lactic acid, malic acid, glycolic acid, tartaric acid, salicylic acid, acetic acid, propionic acid, gluconolactone, lactobionic acid, mixtures thereof and derivatives thereof The above may be selected.
  • the pH adjusting agent may be used without limitation so long as it is a substance capable of maintaining the pH of the composition at pH 3 to 5.
  • pH adjusting agents can be used without limitation, known buffers, for example, tromethamine, HEPES (4- (2-hydroxyethyl) -1-piperazineethanesulfonic acid), HEPPS (3- [4- (2-hydroxyethyl) piperazin -1-yl] propane-1-sulfonic acid), TAPS (3-[[1,3-dihydroxy-2- (hydroxymethyl) propan-2-yl] amino] propane-1-sulfonic acid), MES (2- (N-morpholino) ethanesulfonicacid), TES (2-[[1,3-dihydroxy-2- (hydroxymethyl) propan-2-yl] amino] ethanesulfonic acid), BES (N, N-bis (2-hydroxyethyl)- 2-aminoethanesulfonic acid), TAPSO (3-[[1,3-[
  • the organic acid and its base may be included in a weight ratio of 1: 0.2 to 1: 1.
  • the pH of the composition can be continuously maintained at pH 3 to 5 without irritation to the skin.
  • the organic acid and pH adjusting agent may be included in a weight ratio of 1: 0.2 to 1: 1.
  • the pH of the composition can be continuously maintained at pH 3 to 5 without irritation to the skin.
  • the emulsified cosmetic composition of the present invention is excellent in the skin moisturizing effect, it can continuously alleviate the skin pH change. Improves the skin's water retention ability, alleviates the skin's pH synergism caused by internal and external causes, keeps the skin in the normal range of pH 3 to 5, thereby alleviating and improving various skin symptoms caused by pH changes You can. For example, it can smooth skin texture and relieve skin aging, acne, atopic symptoms, and the like. In addition, the user's satisfaction can be improved by significantly lowering the skin irritation. Therefore, the cosmetic composition of the present invention can be provided in the formulation of cosmetics for moisturizing skin, alleviating pH change.
  • Cosmetics prepared by containing the emulsion cosmetic composition of the present invention as an active ingredient can be prepared in the form of a general emulsion formulation or solubilized formulation.
  • Lotions such as, for example, flexible lotions or nourishing lotions; Latex, such as facial lotion or body lotion; Creams such as nourishing creams, moisture creams, eye creams and the like; essence; Cosmetic ointments; spray; Gels; pack; Sunscreen; Makeup base; Foundations such as liquid type, solid type or spray type; powder; Makeup removers such as cleansing creams, cleansing lotions, cleansing oils; Formulations such as cleansing foams, soaps, cleaning agents such as body washes, and the like.
  • the cosmetics are fatty substances, organic solvents, solubilizers, thickening agents, gelling agents, emollients, antioxidants, suspending agents, stabilizers, foaming agents, fragrances, surfactants, water, ionic emulsifiers, nonionic It may contain auxiliaries commonly used in the cosmetic field such as emulsifiers, fillers, metal ion sequestrants, chelating agents, preservatives, vitamins, blockers, wetting agents, essential oils, dyes, pigments, hydrophilic active agents, lipophilic active agents or lipid vesicles. have.
  • oil, wax and surfactant were added to heat dissolved at 70 °C to 75 °C to prepare an oil phase.
  • As the pH buffer solution an organic acid and its base, or an organic acid and an organic buffer compound were used.
  • the oily phase was added to the aqueous phase heated to 70 ° C to 75 ° C by dispersing a pH buffer solution, polyol, thickener and the like in purified water. Thereafter, the mixture was stirred for 10 minutes under a homomixer 1500 to 3500 rpm and an additive was added at 50 ° C. Thereafter, the mixture was stirred for 5 minutes and cooled to 30 ° C to prepare an oil-in-water emulsion cosmetic composition having a pH buffer system.
  • pH was measured according to the pH test method of the cosmetic test method.
  • 2 g of the composition of each Example and Comparative Example was diluted with 30 ml of purified water, and pH was measured using an F-52 pH meter (HORIBA) according to the functional cosmetics test method.
  • HORIBA F-52 pH meter
  • compositions of Examples 1 to 3 and Comparative Examples 1 and 2 were used to compare the skin pH change mitigation effect and persistence according to the type and presence of the pH buffer system.
  • Twenty men and women suffering from mild atopy in a constant temperature and humidity room maintained at a temperature of 25 ° C and a relative humidity of 70% were measured with a foam cleanser of pH 10 to measure the skin pH of the affected area immediately before the experiment and to artificially raise the skin pH.
  • the skin pH was measured immediately after cleansing the affected area. After applying each formulation, the skin pH was measured up to 240 minutes in increments of 30 minutes and compared with the average value.
  • Skin pH was measured using a skin pH measuring device (Skin-pH-Meter PH905, Courage + Khazaka electronic GmbH, Inc.), the results are shown in Table 4.
  • the cosmetic composition of the present invention can continuously alleviate the pH change of the skin by having a pH buffer system.
  • Example 1 and Comparative Examples 1 to 6 with different buffer systems were used to compare skin texture, exfoliation improvement and skin moisturizing efficacy with or without a pH buffer system.
  • the skin texture and skin pH of 20 men and women in their 50s were measured immediately before the experiment, and the cream was applied to the face for 4 weeks as usual, and measured every 2 weeks.
  • the exfoliation effect was evaluated by coloring the test site with DHA (Chromameter CR300, CK Electronic, Germany) by comparing the test site with no sample and the site with the sample.
  • Skin moisture content was measured using a skin moisture content measuring device (Corneometer CM825, CK Electronic, Germany). The results were compared in terms of improvement compared to before the test.
  • PII stimulation index
  • Example 1 having a pH buffer system shows significant skin texture improvement, skin moisture content improvement and keratin exfoliation improvement compared to Comparative Examples 1 to 6 to help improve aging skin You can see that.
  • Comparative Examples 2 to 5 the skin texture, skin moisture content, and keratin detachment are partially improved, but the degree is significantly lower.
  • Comparative Examples 4 and 6 skin irritation is high, which is unsuitable for users of sensitive skin, and user satisfaction. It was also confirmed that it comes out low.
  • the pH buffer system of the present invention is effective for improving skin texture, improving skin moisture content, and exfoliating keratin.
  • concentration of the organic acid and the content ratio of the organic acid and its base or organic buffer compound contained in the pH buffer system is important for maintaining the above effects.
  • Example 1 and Comparative Examples 1 to 4 with different buffer systems were used to compare skin barrier repair and symptom improvement effects of atopic lesions with or without a pH buffer system.
  • Atopic symptom improvement was visually confirmed in terms of the number of symptom improvement personnel, and it was confirmed through a questionnaire on a 5-point scale after 4 weeks of use.
  • the satisfaction level was confirmed through a questionnaire on a 5-point scale after 4 weeks of use.
  • Example 1 having a pH buffer system showed a skin barrier improvement effect and atopic symptoms improvement effect measured by a significant transdermal moisture loss (TEWL) compared to Comparative Examples 1 to 4.
  • TEWL transdermal moisture loss
  • Example 1 the ratio of atopy improvement personnel was remarkably high, and atopy improvement satisfaction and use satisfaction were also confirmed to be high.
  • Comparative Examples 2 to 4 although there are some improvement in the amount of percutaneous water loss and visually confirmed symptom, the degree is significantly low.
  • the pH buffer system of the present invention can be used to improve the skin barrier and atopic symptoms, and can be used for skin barrier improvement and atopic symptoms.
  • concentration of the organic acid and the content ratio of the organic acid and its base or organic buffer compound contained in the pH buffer system are important for maintaining the above effects.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une composition cosmétique en émulsion ayant un système tampon de pH. La composition cosmétique ayant un système tampon de pH selon la présente invention est peu stimulée par acide organique, et peut atténuer en continu un changement du pH de la peau dû à des causes internes/externes, et améliorer significativement des affections de type trouble de la peau dont le vieillissement, l'acné et l'atopie, par l'amélioration de l'exfoliation des cellules de la peau mortes et l'amélioration de la barrière cutanée.
PCT/KR2016/002341 2015-03-13 2016-03-09 Composition cosmétique en émulsion ayant un système tampon de ph Ceased WO2016148434A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HK18103801.3A HK1244226B (zh) 2015-03-13 2016-03-09 具有ph缓冲系统的乳化化妆材料组合物
CN201680015173.8A CN107427429B (zh) 2015-03-13 2016-03-09 具有pH缓冲系统的乳化化妆材料组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2015-0035050 2015-03-13
KR1020150035050A KR102078140B1 (ko) 2015-03-13 2015-03-13 ｐＨ 완충 시스템을 갖는 유화 화장료 조성물

Publications (1)

Publication Number Publication Date
WO2016148434A1 true WO2016148434A1 (fr) 2016-09-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/002341 Ceased WO2016148434A1 (fr) 2015-03-13 2016-03-09 Composition cosmétique en émulsion ayant un système tampon de ph

Country Status (3)

Country Link
KR (1) KR102078140B1 (fr)
CN (1) CN107427429B (fr)
WO (1) WO2016148434A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110785161B (zh) 2017-06-23 2023-06-20 宝洁公司 用于改善皮肤外观的组合物和方法
KR102113126B1 (ko) * 2017-07-27 2020-05-20 (주)엘지하우시스 완충제를 포함하는 벽지
EP3817717A1 (fr) 2018-07-03 2021-05-12 The Procter & Gamble Company Méthode de traitement d'une affection cutanée
KR102122649B1 (ko) * 2018-08-23 2020-06-15 대구한의대학교산학협력단 유산 및 글루코노락톤을 포함하는 피부장벽 강화용 화장료 조성물
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
US11583488B2 (en) 2020-06-01 2023-02-21 The Procter & Gamble Company Method of improving penetration of a vitamin B3 compound into skin
CN114557915A (zh) * 2022-03-23 2022-05-31 伊美莱(广州)医疗技术有限公司 一种化妆水及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839165A (en) * 1986-02-06 1989-06-13 Beiersdorf Aktiengesellschaft Cosmetic agents for hair
US5932196A (en) * 1994-11-04 1999-08-03 The Procter & Gamble Company Buffered emulsion compositions containing actives subject to acid or base hydrolysis
KR20000016635A (ko) * 1996-06-13 2000-03-25 비숍 미첼 에이. 프로테아제 효소와 산성 완충액 복합물 및 이의용도
WO2007001484A2 (fr) * 2005-06-20 2007-01-04 Playtex Products, Inc. Compositions non irritantes
KR20110069729A (ko) * 2009-12-17 2011-06-23 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드 저자극성 잔류형 스킨 케어 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1357731A (en) * 1970-02-12 1974-06-26 Ethichem Ltd Free flowing powder compositions and ointments containing them'
JPS60158105A (ja) * 1984-01-28 1985-08-19 Susumu Morita 酸性リンス剤
JPH08119828A (ja) * 1994-10-18 1996-05-14 Kanebo Ltd 化粧料
FR2730928B1 (fr) * 1995-02-23 1997-04-04 Oreal Composition a base de vesicules lipidiques a ph acide et son utilisation en application topique
US5935589A (en) * 1997-10-17 1999-08-10 Chesebrough-Pond's Usa Co. Stable cosmetic compositions with different pH emulsions
US6036963A (en) * 1998-02-26 2000-03-14 Chesebrough-Ponds's Usa Co., Division Of Conopco, Inc. Gluconolactones and glucarolactones as anti-irritants in cosmetic compositions
CN102100647B (zh) * 2009-12-16 2013-03-20 麦克森生物科技股份有限公司 一种手脚去死皮角质的有机酸组合物及含该组合物的膜片

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839165A (en) * 1986-02-06 1989-06-13 Beiersdorf Aktiengesellschaft Cosmetic agents for hair
US5932196A (en) * 1994-11-04 1999-08-03 The Procter & Gamble Company Buffered emulsion compositions containing actives subject to acid or base hydrolysis
KR20000016635A (ko) * 1996-06-13 2000-03-25 비숍 미첼 에이. 프로테아제 효소와 산성 완충액 복합물 및 이의용도
WO2007001484A2 (fr) * 2005-06-20 2007-01-04 Playtex Products, Inc. Compositions non irritantes
KR20110069729A (ko) * 2009-12-17 2011-06-23 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드 저자극성 잔류형 스킨 케어 조성물

Also Published As

Publication number Publication date
KR20160109868A (ko) 2016-09-21
KR102078140B1 (ko) 2020-02-17
CN107427429A (zh) 2017-12-01
CN107427429B (zh) 2021-09-07
HK1244226A1 (zh) 2018-08-03

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