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WO2016001121A1 - Procédé pour une utilisation améliorée du potentiel de production de plantes transgéniques - Google Patents

Procédé pour une utilisation améliorée du potentiel de production de plantes transgéniques Download PDF

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Publication number
WO2016001121A1
WO2016001121A1 PCT/EP2015/064665 EP2015064665W WO2016001121A1 WO 2016001121 A1 WO2016001121 A1 WO 2016001121A1 EP 2015064665 W EP2015064665 W EP 2015064665W WO 2016001121 A1 WO2016001121 A1 WO 2016001121A1
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WIPO (PCT)
Prior art keywords
spp
plant
event
plants
gene
Prior art date
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PCT/EP2015/064665
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English (en)
Inventor
Peter Jeschke
Wolfgang Thielert
Marita JOHN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer CropScience AG
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Bayer CropScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of WO2016001121A1 publication Critical patent/WO2016001121A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins

Definitions

  • the invention relates to a method for improving the utilization of the production potential of transgenic plants and for controlling pests such as insects and/or nematodes.
  • Transgenic plants are employed mainly to utilize the production potential of respective plant varieties in the most favourable manner, at the lowest possible input of production means.
  • the aim of the genetic modification of the plants is in particular the generation of resistance in the plants to certain pests or harmful organisms or else herbicides and also to abiotic stress (for example drought, heat or elevated salt levels). It is also possible to modify a plant genetically to increase certain quality or product features, such as, for example, the content of selected vitamins or oils, or to improve certain fibre properties.
  • Herbicide resistance or tolerance can be achieved, for example, by incorporating genes into the useful plant for expressing enzymes to detoxify certain herbicides, so that a relatively unimpeded growth of these plants is possible even in the presence of these herbicides for controlling broad-leaved weeds and weed grasses.
  • Examples which may be mentioned are cotton varieties or maize varieties which tolerate the herbicidally active compound glyphosate (Roundup ® ), (Roundup Ready ® , Monsanto) or the herbicides glufosinate or ioxynil/bromoxynil.
  • Plant parts are to be understood as meaning all above-ground and below-ground parts and organs of plants, such as shoot, leaf, flower and root, by way of example leaves, needles, stalks, stems, flowers, fruit bodies, fruits and seed, and also roots, tubers and rhizomes.
  • the plant parts also include harvested material and also vegetative and generative propagation material, for example cuttings, tubers, rhizomes, slips and seed. Summary of the invention
  • One aspect refers to a method for improving the utilization of the production potential of a transgenic plant and/or for controlling/combating/treating pests, characterized in that the plant is treated with an effective amount of the compound of formula (I)
  • transgenic plant contains at least one cry-gene or a cry-gene fragment coding for a Bt toxin.
  • transgenic plant is a vegetable plant, maize plant, soybean plant, cotton plant, tobacco plant, rice plant, sugar beet plant, oilseed rape plant or potato plant.
  • One preferred embodiment refers to the method described above, characterized in that the use form of the compound of formula (I) is present in a mixture with at least one mixing partner.
  • One preferred embodiment refers to the method described above, characterized in that the Bt toxin of a Bt-plant is encoded by a Bt-gene or fragment thereof comprising event MON87701.
  • Another aspect refers to a synergistic composition
  • a synergistic composition comprising a Bt toxin and the compound of formula (I) as described above.
  • One preferred embodiment refers to said synergistic composition, characterized in that the Bt toxin is encoded by a cry gene or a cry-gene fragment selected from the group consisting of cryl, cry2, cry3, cry 5 and cry 9.
  • One preferred embodiment refers to said synergistic composition, characterized in that the Bt toxin is encoded by a cry gene or a cry-gene fragment selected from the group consisting of especially preferred are crylAb, crylAc, cry3A, cry3B and cry9C.
  • One preferred embodiment refers to said synergistic composition, characterized in that the Bt toxin is encoded by a cry gene or a cry-gene fragment selected from the subgroup crylA, preferably cryl Aa, cryl Ab, cryl Ac or a hybrid thereof (e.g., a hybrid of cryl Ac and cryl Ab).
  • One preferred embodiment refers to said synergistic composition, characterized in that the Bt toxin is encoded by a Bt-gene or fragment thereof comprising event MON87701.
  • a Bt-plant preferably a Bt-soybean plant comprising event MON87701 or a Bt-soybean plant comprising event MON87701 and MON89788, characterized in that at least 0.00001 g of the compound of formula (I) is attached to it.
  • Production potential refers to the yield of a transgenic plant under specific conditions. "Improving the utilization of the production potential of transgenic plants” thus refers to an increase of yield under unfavorable environmental conditions such as use of herbicides, drought stress, cold stress, stress induced by insects, nematodes, or fungis etc. compared to the yield of such plants under the same conditions without the use of the compound of formula (I) as described herein.
  • the method can also be used for an increased control of pests such as insects and/or nematodes.
  • a transgenic plant such as a Bt-plant and the compound of formula (I) can show better /control of insects and/or nematodes compared to the expected effect.
  • transgenic plants in particular useful plants, are treated with the compound of formula (I) to increase agricultural productivity and/or to control pests, especially nematodes and insects.
  • the invention refers to a method for combating pests by treating transgenic plants, preferably insect-resistant transgenic plant such as Bt-plants or Vip-plants with the compound of formula (I).
  • GMOs genetically modified organisms
  • plants e.g. plants or seeds
  • transgenic plants are plants of which a heterologous gene has been stably integrated into the genome.
  • heterologous gene essentially means a gene which is provided or assembled outside the plant and when introduced in the nuclear, chloroplastic or mitochondrial genome gives the transformed plant new or improved agronomic or other properties by expressing a protein or polypeptide of interest or by downregulating or silencing other gene(s) which are present in the plant (using for example, antisense technology, cosuppression technology, RNA interference - RNAi - technology or microRNA - miRNA - technology).
  • a heterologous gene that is located in the genome is also called a transgene.
  • a transgene that is defined by its particular location in the plant genome is called a transformation or transgenic event.
  • the treatment according to the invention may also result in superadditive (“synergistic") effects.
  • superadditive for example, reduced application rates and/or a widening of the activity spectrum and/or an increase in the activity of the active compounds and compositions which can be used according to the invention, better plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or to water or soil salt content, increased flowering performance, easier harvesting, accelerated maturation, higher harvest yields, bigger fruits, larger plant height, greener leaf color, earlier flowering, higher quality and/or a higher nutritional value of the harvested products, higher sugar concentration within the fruits, better storage stability, increased combating of pests, especially nematodes and insects and/or processability of the harvested products are possible, which exceed the effects which were actually to be expected.
  • the active compound combinations according to the invention may also have a strengthening effect in plants. Accordingly, they are also suitable for mobilizing the defense system of the plant against attack by unwanted microorganisms. This may, if appropriate, be one of the reasons of the enhanced activity of the combinations according to the invention, for example against fungi.
  • Plant-strengthening (resistance-inducing) substances are to be understood as meaning, in the present context, those substances or combinations of substances which are capable of stimulating the defense system of plants in such a way that, when subsequently inoculated with unwanted microorganisms, the treated plants display a substantial degree of resistance to these microorganisms.
  • unwanted microorganisms are to be understood as meaning phytopathogenic fungi, bacteria and viruses.
  • the substances according to the invention can be employed for protecting plants against attack by the abovementioned pathogens within a certain period of time after the treatment.
  • the period of time within which protection is effected generally extends from 1 to 10 days, preferably 1 to 7 days, after the treatment of the plants with the active compounds.
  • Plants and plant cultivars which are preferably to be treated according to the invention include all plants which have genetically modified material which impart particularly advantageous, useful traits to these plants (whether obtained by breeding and/or biotechnological means).
  • Plants and plant cultivars which are also preferably to be treated according to the invention are resistant against one or more biotic stresses, i.e. said plants show a better defense against animal and microbial pests, such as against nematodes, insects, mites, phytopathogenic fungi, bacteria, viruses and/or viroids.
  • nematode or insect resistant plants are described in e.g. U.S. Patent Applications 11/765,491, 11/765,494, 10/926,819, 10/782,020, 12/032,479, 10/783,417, 10/782,096, 11/657,964, 12/192,904, 11/396,808, 12/166,253, 12/166,239, 12/166,124, 12/166,209, 11/762,886, 12/364,335, 11/763,947, 12/252,453, 12/209,354, 12/491,396, 12/497,221, 12/644,632, 12/646,004, 12/701,058, 12/718,059, 12/721,595, 12/638,591, and in WO 11/002992, WO 11/014749, WO 11/103247, WO 11/103248, WO 12/135436, WO 12/135501.
  • Plants and plant cultivars which may also be treated according to the invention are those plants which are resistant to one or more abiotic stresses.
  • Abiotic stress conditions may include, for example, drought, cold temperature exposure, heat exposure, osmotic stress, flooding, increased soil salinity, increased mineral exposure, ozone exposure, high light exposure, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients, shade avoidance.
  • Plants and plant cultivars which may also be treated according to the invention are those plants characterized by enhanced yield characteristics. Increased yield in said plants can be the result of, for example, improved plant physiology, growth and development, such as water use efficiency, water retention efficiency, improved nitrogen use, enhanced carbon assimilation, improved photosynthesis, increased germination efficiency, inproved combating of insects and accelerated maturation.
  • Yield can furthermore be affected by improved plant architecture (under stress and non-stress conditions), including but not limited to, early flowering, flowering control for hybrid seed production, seedling vigor, plant size, internode number and distance, root growth, seed size, fruit size, pod size, pod or ear number, seed number per pod or ear, seed mass, enhanced seed filling, reduced seed dispersal, reduced pod dehiscence and lodging resistance.
  • Further yield traits include seed composition, such as carbohydrate content, protein content, oil content and composition, nutritional value, reduction in anti-nutritional compounds, improved processability and better storage stability.
  • ASR36 Scotts stolonifera US 2006- phosphate synthase (EPSPS) encoding gene
  • EPSPS Internation synthase
  • NPTII encoding gene from E. coli was L. (Tobacco)
  • PLRV virus virus
  • Aventis Brassica viridochromogenes an aerobic soil bacteria.
  • PPT normally acts to inhibit glutamine
  • Acetylated PPT is inactive.
  • AHAS acetohydroxyacid synthase
  • MIR604 (OECD unique identifier: SYN- IR605-5) and GA21 (OECD unique
  • MIR60 Syngenta (Liberty) is derived from BT11, which Zea mays
  • 4 x Seeds, Inc. contains the crylAb gene from Bacillus L. (Maize)
  • PAT phosphinothricin N-acetyltransferase
  • Corn rootworm-resistance is derived from
  • MIR604 which contains the mcry3A gene
  • glyphosate herbcicide is derived from GA21
  • PAT phosphinothricin acetyltransferase
  • NK603 OECD unique identifier
  • MON89034 (OECD identifier: MON- 89034-3) and MON88017 (OECD
  • cry genes and glyphosate tolerance is
  • EPSPS 5-enolpyruvylshikimate-3- phosphate synthase
  • insects is derived from two crygenes present
  • herbcicide is derived from NK603.
  • MON- Company lines NK603 (OECD identifier: MON- L. (Maize)
  • PPT normally acts to inhibit glutamine
  • Acetylated PPT is inactive.
  • HCR-1 (Aventis napus line T45. This trait is mediated by the rapa (Polish
  • EPSPS Achromobacter sp Brassica
  • AMP A aminomethylphosphonic acid
  • Canola Canola
  • EPSPS phosphate synthase
  • Zaden BV 074492 RM3-6 the bar gene from S. hygroscopicus, which ory
  • SAM S- adenosylmethionine
  • CMV Cucumber mosiac virus
  • WMV mosaic virus 2 resistant squash
  • ALS acetolactate synthase
  • herbicides was via the introduction of a (Carnation) chlorsulfuron tolerant version of the
  • ALS acetolactate synthase
  • A2704- soybean produced by inserting a modified
  • PPT normally acts to inhibit glutamine (sugar beet) 2006/108674
  • Acetylated PPT is inactive.
  • DP3560 Hi-Bred genes glyphosate N-acetlytransferase, Glycine max WO 43 Internation which detoxifies glyphosate, and a modified L. (Soybean) 2008/054747 al Inc. acetolactate synthase (A
  • GU262 (Aventis phosphinothricin acetyltransferase (PAT)
  • MON8 Monsanto altered fatty acid levels (mid-oleic and low Glycine max WO 7705 Company saturate); WO 2010037016 L. (Soybean) 2009064652
  • MON8 Monsanto stearidonic acid comprising oil; WO Glycine max
  • MON8 inserting a modified 5- 9788, Monsanto enolpyruvylshikimate-3 -phosphate synthase Glycine max WO MON1 Company (EPSPS) encoding aroA (epsps) gene from L. (Soybean) 2009102873 9788 Agrobacterium tumefaciens CP4;
  • EPSPS Monsanto enolpyruvylshikimate-3 -phosphate synthase Glycine max WO MON1 Company
  • cry IF gene from Bacillus
  • cry 1 Ac gene from Bacillus thuringiensis and hirsutum
  • VIP3A Insect resistance
  • US2009181399 hirsutum WO200403998 2 Seeds, Inc.
  • Calgene (Umbellularia californica).
  • MON- with MON1445 (OECD identifier: MON-
  • BIOSCIE Glyphosate tolerance WO 2007/017186 hirsutum
  • BIOSCIE Insect resistance (cry2Ae); WO2008151780 hirsutum
  • GBH61 produced by inserting 2mepsps gene into WO
  • MON88913 MON- 88913-8
  • 15985 OECD identifier:
  • EPSPS EPSPS synthase
  • MON- Company (OECD identifier: MON- 15985-7)
  • JOPLI disease (fungal) resistance (trichothecene 3- WO201007621 Participati Wheat
  • CHINA Transgenic rice Kefeng 6 is a transformation
  • Kefeng NAT event containing two insect-resistant genes Oryza
  • MS45 anther-specific 5126 (Zea mays)
  • ZM-AAl polygalacturonase 47 (Zea mays)
  • DSRED2 35S (Cauliflower Mosaic Virus)
  • the aad-1 gene confers tolerance
  • CRY3A metallotionin-like gene
  • coding sequence modified to include a
  • MON 87427 comprises the promoter
  • P-e35S operably linked to
  • CP4 EPSPS protein operably linked to a
  • T-NOS nopaline synthase
  • Ph4a748 ABBC sequence including the
  • Ph4a748 sequence
  • h3At first intron of gene II of the histone
  • pDAB4468-0416 herbicide tolerance in soybean plants - referred to herein as pDAB4468-0416.
  • the invention provides DNA compositions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

L'invention concerne un procédé permettant d'améliorer l'utilisation du potentiel de production de plantes transgéniques par traitement de la plante à l'aide d'une quantité efficace d'un composé de formule (I).
PCT/EP2015/064665 2014-07-01 2015-06-29 Procédé pour une utilisation améliorée du potentiel de production de plantes transgéniques Ceased WO2016001121A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14175134.7 2014-07-01
EP14175134 2014-07-01

Publications (1)

Publication Number Publication Date
WO2016001121A1 true WO2016001121A1 (fr) 2016-01-07

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Application Number Title Priority Date Filing Date
PCT/EP2015/064665 Ceased WO2016001121A1 (fr) 2014-07-01 2015-06-29 Procédé pour une utilisation améliorée du potentiel de production de plantes transgéniques

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WO (1) WO2016001121A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017198451A1 (fr) * 2016-05-17 2017-11-23 Bayer Cropscience Nv Procédé pour augmenter le rendement dans des céréales à grains fins telles que le blé et le riz
US10227492B2 (en) 2015-11-16 2019-03-12 StoreDot Ltd. Modifications of the sol-gel films and production processes thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009064652A1 (fr) * 2007-11-15 2009-05-22 Monsanto Technology Llc Plante et graine de soja correspondant à l'événement transgénique mon87701 et procédés pour les détecter
EP2631235A2 (fr) * 2010-08-31 2013-08-28 Meiji Seika Pharma Co., Ltd. Agents de contrôle de nuisibles
EP2634174A2 (fr) * 2012-02-29 2013-09-04 Meiji Seika Pharma Co., Ltd. Dérivé hétérocyclique contenant de l'azote ayant un groupe 2-imino et agent antiparasitaire comprenant celui-ci
EP2633756A1 (fr) * 2012-02-29 2013-09-04 Meiji Seika Pharma Co., Ltd. Composition pour la contrôle des organismes nuisibles comprenant un derivé d'iminopyridine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009064652A1 (fr) * 2007-11-15 2009-05-22 Monsanto Technology Llc Plante et graine de soja correspondant à l'événement transgénique mon87701 et procédés pour les détecter
EP2631235A2 (fr) * 2010-08-31 2013-08-28 Meiji Seika Pharma Co., Ltd. Agents de contrôle de nuisibles
EP2634174A2 (fr) * 2012-02-29 2013-09-04 Meiji Seika Pharma Co., Ltd. Dérivé hétérocyclique contenant de l'azote ayant un groupe 2-imino et agent antiparasitaire comprenant celui-ci
EP2633756A1 (fr) * 2012-02-29 2013-09-04 Meiji Seika Pharma Co., Ltd. Composition pour la contrôle des organismes nuisibles comprenant un derivé d'iminopyridine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10227492B2 (en) 2015-11-16 2019-03-12 StoreDot Ltd. Modifications of the sol-gel films and production processes thereof
WO2017198451A1 (fr) * 2016-05-17 2017-11-23 Bayer Cropscience Nv Procédé pour augmenter le rendement dans des céréales à grains fins telles que le blé et le riz

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