WO2016096818A1 - Désinfectant contenant du peroxyde d'hydrogène et un tensioactif végétal, et procédé d'aseptisation - Google Patents
Désinfectant contenant du peroxyde d'hydrogène et un tensioactif végétal, et procédé d'aseptisation Download PDFInfo
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- WO2016096818A1 WO2016096818A1 PCT/EP2015/079740 EP2015079740W WO2016096818A1 WO 2016096818 A1 WO2016096818 A1 WO 2016096818A1 EP 2015079740 W EP2015079740 W EP 2015079740W WO 2016096818 A1 WO2016096818 A1 WO 2016096818A1
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- Prior art keywords
- disinfectant
- aerosol
- disinfection
- generating unit
- surfactant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/14—Disinfection, sterilisation or deodorisation of air using sprayed or atomised substances including air-liquid contact processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
- A61L2/186—Peroxide solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/202—Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/25—Rooms in buildings, passenger compartments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/10—Apparatus features
- A61L2209/13—Dispensing or storing means for active compounds
- A61L2209/132—Piezo or ultrasonic elements for dispensing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
- A61L2209/211—Use of hydrogen peroxide, liquid and vaporous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
- A61L2209/212—Use of ozone, e.g. generated by UV radiation or electrical discharge
Definitions
- the invention relates to a disinfectant.
- the invention relates to a method for sterilizing rooms, a device for carrying out the method according to the invention and a system for the sterilization of rooms.
- a soil germination is performed by closing the space to be sterilized, in particular sealed, and then fumigated. After a predeterminable exposure time of, for example, two hours, the room is considered sterilized. Due to the aggressiveness of the disinfectant used, which usually has comparatively high concentrations of chlorine-containing compounds or ozone, people must not be in this room during the exposure time. After completing the sterilization, ventilate the room to remove the gas used. Then the room can be entered again by people.
- the disadvantage of this approach is that with the airing and with the entry of people into the room a re-germination takes place. This re-germination takes place so fast that within a very short time the germ status is restored, as it existed before the sterilization.
- an injection device which is suitable for introducing disinfectants and / or fragrances in a flow of a line system.
- the agents preferably in liquid form
- an injection head is provided, which can be designed in particular as a nozzle and particularly preferably as a hollow cone nozzle.
- the injection takes place here at intervals.
- the disadvantage of this is that in the interval pauses in which no fumigation takes place, a recontamination occurs.
- a permanently safe sterilization is achieved and a recontamination effectively avoided.
- the duration of the process is arbitrarily long in terms of time, without the need to interrupt the intended use of the space or area to be sterilized.
- a continuous killing of pathogenic, unhealthy or similar germs is hereby achieved and prevents recontamination for the duration of the method used.
- said germs include bacteria, viruses, fungi, spores, fine dusts and the like.
- a successful continuous process management for sterilization depends on the synergetic interaction of individual features essential to the invention.
- the method according to the invention can be used in a large number of fields.
- the health sector there preferably in hospitals, nursing homes, medical practices and the like, in the food industry, there especially in livestock, the processing industry, in particular butcheries, bakeries and the like, and warehousing.
- Applications in the private sector are also conceivable.
- the Specified limits may result from experience in each sector.
- the respective limit value according to the invention is preferably a legally prescribed limit, which ensures that the use of the individual components in the disinfectant and thus the disinfectant as such for humans no harmful effect unfold.
- the respective limit value is given by the legal occupational exposure limit (AGW, formerly Maximum Occupational Concentration - MAK) for the components of the disinfectant.
- AGW legal occupational exposure limit
- the respective lower limit value is preferably adhered to. This is particularly the case in the food industry, where both occupational exposure limits and food hygiene regulation (LMHV) limits apply.
- the total concentration of the disinfectant in the aerosol is chosen so that the individual concentration of both the oxidizing agent and the surfactant are below such a limit.
- Spatial germination methods known from the prior art typically make use of concentrations which are significantly above the prescribed limits in order to be able to realize sterilization at all.
- the prevailing opinion in the prior art is therefore that for proper sterilization comparatively high concentrations of active ingredients must be used that are harmful to humans, animals, food and the like.
- the invention proposes here in deliberate departure from the prior art, a new way.
- a disinfectant at least consisting of an oxidizing agent and a surfactant in a prescribed concentration in the aerosol has never considered possible effectiveness against germs.
- Disinfection according to the invention is preferably achieved in a surprising manner even at comparatively lower total concentrations.
- a total concentration of 0.01 ml to 0.05 ml of disinfectant / m 3 of room air is sufficient for a spatial disinfection according to the invention.
- a concentration of 0.02 ml of disinfectant / m 3 room air has proved to be particularly advantageous.
- the total concentrations used are thus significantly below the AGW of suitable for the formation of the disinfectant according to the invention oxidizing agents such as in particular, sodium hypochlorite (0.5 ml / m 3 ), hydrogen peroxide (0.5 ml / m 3 ), ozone (0.1 ml / m 3 ) or peroxyacetic acid (10 ml / m 3 ).
- oxidizing agents such as in particular, sodium hypochlorite (0.5 ml / m 3 ), hydrogen peroxide (0.5 ml / m 3 ), ozone (0.1 ml / m 3 ) or peroxyacetic acid (10 ml / m 3 ).
- the total concentrations of the disinfectant in the aerosol are well below those for dust in general and for surfactants in particular AGW of about 10 ml / m 3 .
- the aerosol used for sterilization is thus not only harmless to humans but also effective against germs and does not affect in any way the intended use of the space to be sterilized, whereby the inventive method provides by its continuous application for an initial sterilization and beyond a resuspension prevented in an advantageous manner.
- the inventive method can thus be carried out continuously without consideration of people present in the room.
- a recontamination, as occurs in the known from the prior art method can be advantageously avoided with the inventive design, so that in the space to be sterilized even with the introduction of fresh germs in said space, for example by ventilation, a constantly low Germ level can be maintained.
- a suspended aerosol is generated from the disinfectant.
- the disinfection center mixed with air. Air serves as a carrier medium for the disinfectant.
- the disinfectant can be distributed in a simple manner in the space to be sterilized or even in parts thereof by way of air convection.
- a sterilization of the air itself and all surfaces in the space to be sterilized is thereby achieved.
- surfaces which have been sterilized insufficiently in the prior art usually by wiping can be almost completely sterilized by the invention.
- air as a carrier medium now also possible to sterilize surfaces that can not be sterilized by merely wiping. These include in particular rough surfaces, porous surfaces, textured surfaces, textife surfaces, in particular curtains, bedding, clothing and the like.
- the aerosol penetrates into microscopic structures of these surfaces and also sterilizes them in places that are inaccessible to conventional methods.
- air in the form of ambient air is used.
- Air-like in this context means that the gas mixture contains nitrogen and oxygen in a proportion sufficient for the metabolism of humans and / or animals.
- the ambient air is not or not suitable as such for the generation of the aerosol or for other reasons can not be used as a carrier medium, this is particularly advantageous.
- Floating ability of the aerosol is advantageous because it improves the distribution availability of the aerosol.
- the disinfectant is therefore sprayed according to a preferred embodiment of the invention to fine droplets with a diameter below 10 pm.
- a buoyant and stable aerosol can be produced in this way. It has also been found that droplets with such a diameter, in particular in the case of structured and / or porous surfaces, as occur in particular in the case of textiles, lead to particularly effective sterilization due to improved material handling. To further improve material handling, it is preferred to produce droplets with a diameter below 5 pm and more preferably between 1 pm and 3 pm.
- the aerosol is continuously introduced after its production in the space to be sterilized.
- a device suitable for carrying out the method can be set up in the space to be sterilized or the area to be sterilized.
- a device is mobile adapted to sterilize various rooms or areas of space as desired or necessary.
- the device preferably has moving means.
- the moving means may be preferred as rollers, wheels, runners or the like be educated.
- the method according to the invention is preferably scalable for each room size.
- the performance of the device is adapted to the size of the space to be sterilized.
- the number of drawn up in a room devices for the purpose of Sca 'ieriana adapted to the size of the room. In this way it is possible to adapt the inventive method to any room size.
- the aerosol is introduced indirectly into the space to be sterilized. It is not necessary here to set up the device in the space to be sterilized. Rather, this is only line technology associated with the space to be sterilized. Such a procedure advantageously allows a spatial decoupling of the aerosol production from its place of use. This results in a whole series of advantages. On the one hand, any effects associated with aerosol production, such as, in particular, a perceived unpleasant noise development in the space to be sterilized are imperceptible. This is particularly beneficial in the hospital where people who are in need of rest are typically treated. On the other hand, the device is also optically not present in the space to be sterilized, whereby the appearance of the room is not unduly disturbed.
- the device is technically connected to more than one room, which can be sterilized with a device several rooms.
- the device is placed at a junction of the ventilation system to equally sterilize as many rooms as possible.
- the present in such a ventilation system air flow flows around the device. It serves advantageously as a carrier medium for the disinfectant in the aerosol.
- the invention further relates to a disinfectant for use in the method according to the invention.
- a disinfectant for use in the method according to the invention.
- This is characterized by a special active ingredient combination of at least one oxidation center! and a surfactant.
- the Applicant has found that the combination of active substances according to the invention exhibits a synergistic effect in the control of germs and is therefore particularly effective. It is thereby possible to use comparatively low concentrations of disinfectant for sterilization, which makes possible a harmless process for humans, continuous process control in the first place.
- the oxidizing agent of hydrogen peroxide (H 2 0 2 ) is formed. It is characterized in an advantageous manner by a comparatively high standard electrode potential (redox potential under standard conditions) of 1.78 V, which makes it one of the strong oxidizing agents.
- redox potential under standard conditions 1.78 V
- hydrogen peroxide is particularly advantageous in the field of soil decontamination because it is reduced to water (H 2 O) during sterilization, so that no harmful by-products are formed. Further, hydrogen peroxide tends to decompose into water and oxygen as part of a disproportionation reaction.
- the surfactant used according to the invention as a component in the disinfectant is, according to a preferred feature of the invention, a vegetable surfactant.
- plant-based means that the surfactant can be obtained from vegetable raw materials, in particular fats. It can preferably be provided that the disinfectant contains more than one surfactant in order to achieve the broadest possible disinfecting efficacy. It has been found in this regard that different surfactants are different effective against different types of germs. Preferably, it is provided here that all surfactants used in the disinfectant from a single plant source are recoverable. This may be present in particular coconut oil.
- the Applicant has found that the surfactants obtainable from the fatty acids contained in coconut oil, in particular the carboxylates of palmitic, lauric, myristic and oleic acids, have a particularly high activity and a broad spectrum in the control of germs.
- the effectiveness of the disinfectant on the type and the exact quantitative composition of the individual components of the disinfectant is dependent. It is possible in principle to produce the aerosol according to the invention both from a disinfectant in the solid state and in the liquid state. However, it is preferred to form the disinfectant as an aqueous solution because of its easier handling. Preferably, exclusively deionized water is used for this purpose in order to provide the purest possible disinfectant, and in this way to avoid possible side effects or side reactions with the active ingredients.
- the disinfectant preferably comprises at least 95% by weight to 98% by weight of fully deionized water, 1.5% by weight to 4.9% by weight of hydrogen peroxide and 0.1% by weight to 0.5% by weight of at least one surfactant.
- the disinfectant consists of at least 97% by weight of deionized water, 2.7% by weight of hydrogen peroxide and 0.3% by weight of a surfactant mixture obtainable from coconut oil.
- the aforementioned compositions have proven to be particularly advantageous in terms of the sterilization time, the sterilization efficiency and the germicidal spectrum.
- the disinfectant ozone as a further oxidizing agent.
- this can be realized either subsequently in the course of the degermination process or already in advance of the process by providing an ozone-containing disinfectant.
- the ozone with a standard electrode potential of 2.075 V is higher than that of hydrogen peroxide and accordingly is a stronger oxidizing agent.
- the introduced in the disinfectant concentration of ozone is also chosen in the sense of carrying out the method according to the invention that it is not harmful to health in the aerosol for humans. It has been found that such a concentration of ozone in conjunction with the hydrogen peroxide contained in the disinfectant, the total redox potential increased up to 2.86V. It is possible by the aforementioned combination of oxidants to increase the redox potential above the value of their individual components, so that the total potential in a synergistic manner reaches the standard electrode potential of fluorine.
- the invention further relates to a device for carrying out the method according to the invention.
- the device has a disinfectant tank for providing a disinfectant.
- the disinfectant tank is preferably connected by line technology with a reservoir.
- the storage tank is used to fill the disinfectant tank.
- the capacity of the reservoir is adaptable to the size of the device. Depending on the size of the device, it typically takes up between 10 I and 20 L of disinfectant. However, as a function of the space / space to be sterilized, substantially larger containers are also conceivable.
- reservoir and disinfectant tank are connected to each other with the interposition of a pump.
- the pump may preferably be designed as a peristaltic pump, diaphragm pump or the like.
- the disinfectant is preferably pumped from the reservoir into the disinfectant tank.
- the disinfection agent tank has a level sensor.
- the level sensor is preferably provided. This is control technology connected to the pump, so that is automatically pumped from the reservoir falls below the Fülistand Left automatically disinfectant to comply with the necessary for proper functioning, in particular the Zerstäubungsmembran liquid level within the disinfectant tank.
- the device according to the invention further comprises a line connected to the disinfectant tank aerosol generating unit for generating an aerosol from the disinfectant.
- the aerosol generating unit has a sputtering membrane. This is preferably designed such that it can oscillate in an adjustable frequency.
- the frequency is preferably set as a function of the quantity of aerosol to be generated. Further preferably, the frequency may vary depending on the size of be set generating disinfectant droplets. Preferably, it is provided to allow the sputtering membrane to oscillate at a frequency in the ultrasonic range. As a result, particularly small disinfectant droplets in the range below 10 pm can be generated.
- the device furthermore has a ventilation unit connected in line with the aerosol generating unit for sucking in the ambient air and for discharging the aerosol.
- a ventilation unit connected in line with the aerosol generating unit for sucking in the ambient air and for discharging the aerosol.
- ozone can be added to the disinfectant during continuous operation.
- the device has an ozone generating unit.
- the ozone generating unit may preferably be in the form of ozone candles.
- the ozone candles are conductively connected to the disinfectant tank for introducing the ozone generated in the disinfectant.
- other ozone generating units known from the prior art can also be used. These can be operated either alone or in combination with each other.
- the device has an error output unit.
- This serves to display errors associated with the operation of the device as a whole or of the individual components. In particular, these may be errors in terms of the level in the disinfectant tank. This can be caused by a defect in the pump, the level sensor or similar.
- errors regarding the aerosol generating unit may be displayed. In particular, a membrane defect can be displayed. Also errors in connection with the ventilation unit, in particular a defective drive or the like, can be displayed. Overall, this leads to a simplification of maintenance and possibly a repair of the device, since sources of error can be detected and displayed directly.
- the error output unit is designed as an LED field. Preferably, it is provided to assign each component a different color LED. Particularly preferred are errors of the disinfectant tank by means of a green LED displayed. Further preferably, errors of the aerosol generating unit are indicated by means of a red LED. Also preferably, faults of the ventilation unit are indicated by means of a yellow LED.
- the error output unit is designed as a display unit.
- it is a touch display to view different fault statuses display.
- the device has a data memory in which error messages are retrievably stored.
- the device further has a control device.
- a control device serves in particular to control the individual components.
- the control device may be connected to control with pumps and / or valves and / or other flow-regulating devices.
- the control device can be designed to detect fault conditions.
- the control device is connected to corresponding sensors.
- these sensors can preferably be arranged in the individual components.
- the control device is connected to the error output unit for this purpose. Previously detected error conditions can thereby be reported to the error output unit, which displays them in such a case.
- the invention relates to a system for the sterilization of rooms or areas thereof.
- the system consists of a device according to the invention and a disinfectant according to the invention.
- a permanently safe sterilization is achieved and a recontamination effectively avoided.
- the unknown from the prior art synergistic combination of Device according to the invention and disinfectant according to the invention make possible the continuous process control of the method according to the invention.
- the preferred features of the individual components of the system according to the invention act synergistically for an overall further improvement of the system according to the invention beyond the sum of its individual parts.
- the invention relates to a method for sterilizing rooms or areas thereof, wherein a disinfectant is used, which comprises an oxidizing agent and a surfactant, in which a suspended aerosol is generated from the disinfectant and continuously introduced into the space to be sterilized in which the total concentration of the disinfectant in the aerosol is set, wherein in each case a maximum limit value for the individual concentration of the oxidizing agent and of the surfactant in the aerosol is specified.
- the aerosol consists of a disinfectant at least consisting of 95 to 98 wt .-% deionized water, 1, 5 to 4.9 wt .-% H 2 0 2 and 0.1 to 0.5 wt .-% at least one surfactant, wherein between 0.01 and 0.05 ml of disinfectant per 1 m 3 of room air are atomized by means of a membrane oscillating at an ultrasonic frequency to droplets with a diameter of less than 5 pm.
- ozone is generated and introduced into the disinfectant prior to the generation of the aerosol.
- the invention also relates to a disinfectant for use in accordance with the invention, comprising an oxidizing agent and a surfactant.
- the disinfectant is formed as an aqueous disinfectant solution in which the oxidizing agent is present as H 2 0 2 and the surfactant as a vegetable surfactant. It is further preferred that the disinfectant solution has from 95 to 98% by weight of deionized water, from 1.5 to 4.9% by weight of H 2 O 2 and from 0.1 to 0.5% by weight of at least one vegetable surfactant ,
- the aqueous disinfectant solution comprise further vegetable surfactants, all of the surfactants contained in the disinfectant solution being obtainable from coconut oil.
- the aqueous disinfectant solution has another oxidizing agent in the form of ozone.
- the invention also relates to a device for carrying out the method according to the invention, comprising a disinfectant tank for providing a disinfectant, an aerosol generating unit connected to the disinfectant tank for generating an aerosol from the disinfectant and a ventilation unit connected to the aerosol generating unit for sucking in ambient air and for discharging the air aerosol.
- the aerosol generating unit has a sputtering membrane designed to be oscillatable with an ultrasonic frequency.
- Device side further preferred is an ozone generating unit, which is connected in terms of line technology with the disinfectant tank for introducing the ozone generated in the disinfectant.
- the invention also relates to a system for the sterilization of rooms, comprising a disinfectant according to the invention and a device according to the invention.
- the invention relates to a method for disinfecting medical tools and / or body parts.
- MRSA methicillin-resistant Staphylococcus aureus
- VRSA vancomycin-resistant Staphylococcus aureus
- MRGP multi-resistant gram-positive bacteria
- MRGN multi-resistant gram-positive bacteria
- Disinfectant dispensers should be located at each entrance and exit of sanitary areas, such as patient rooms. Medical staff, patients and other visitors are encouraged to disinfect before and after any potential exposure. However, this requires a special procedure, with which the non-medical staff is unfamiliar and the medical staff often only sporadically complies due to the time required. In addition, the hands usually remain moist after disinfection. Often this leads to the fact that the hands are dried by means of non-sterile aids, in particular garments. The result is in any case an insufficient disinfection and a relatively high transmission risk of infections.
- the above-described disinfectant is not only suitable for the sterilization of rooms, but also for the disinfection of medical tools, preferably surgical instruments, dental tools and / or covered and uncovered body parts, in particular hands and feet.
- a method in which a disinfectant is used, which comprises an oxidizing agent and a surfactant, in which a suspended aerosol is produced from the disinfectant and continuously brought into contact with the object to be disinfected and / or the body part, wherein in each case a maximum limit for the individual concentration of Oxidafionsffens and the surfactant in the aerosol is given.
- "Continuously contacting" with respect to the disinfection of medical tools, preferably surgical instruments, dental tools and / or of covered and uncovered body parts, especially hands and feet, means that the aerosol is non-stop at least for a minimum period of time appropriate to disinfection the object or body part to be disinfected is contacted.
- the aerosol also passes without problem to those places that can not be disinfected, for example in the context of a normal hand disinfection or only with the correct movement technique of the hands.
- the palm of the hand with liquid disinfectants is insufficiently disinfectable.
- the Papillarancen the palm are usually arranged such that in each case between two Papillarangn a furrow is formed. The distance of the Papillarangn leads to a kind of lotus effect, which liquid due to their surface tension can not penetrate into the furrows. Germs that have accumulated in these furrows can not be combated with conventional disinfectants, therefore, or insufficiently.
- the aerosol according to the invention penetrates without problem into skin furrows of all kinds and also causes an almost complete disinfection there.
- the disinfection according to the invention by means of the aerosol no moisture film on the surface to be disinfected Object or body part, whereby this advantageously does not have to be dried after complete disinfection. This also effectively minimizes the risk of re-contamination.
- a disinfection according to the invention is achieved in a surprising manner already at comparatively lower total concentrations.
- a disinfection at a total concentration of 0.01 ml to 0.05 ml of disinfectant / m 3 of room air which has already proven itself in the spatial disinfection, reachable.
- a higher total concentration is set for the disinfection.
- the duration of the required exposure time to achieve a complete disinfection is thereby advantageously shortened.
- total concentrations between 0.3 to 1, 0 ml / m 3 , more preferably 0.5 to 0.7 ml / m 3 , the aforementioned total concentrations are well below the AGW for aerosols of 10 ml / m 3 and are insofar as classified as safe for health.
- the aerosol is contacted with the object or body part to be disinfected for a minimum period of time.
- the minimum duration is the time required to achieve near complete disinfection. This depends primarily on the type, size and amount of the objects or body parts to be disinfected and on the amount and total concentration of the aerosol. If one of the preferred amounts and total concentration of the aerosol is adjusted, the minimum duration, depending on the other factors, is between 20 and 60 seconds, preferably between 20 and 30 seconds. Even a minimum duration of less than 10 seconds can be achieved with a corresponding amount of aerosol.
- the objects After reaching the minimum duration, the objects are disinfected and can be removed from the exposure area of the aerosol and immediately used as intended. Alternatively, the objects may remain in the exposure region of the aerosol beyond the minimum duration. This will give the objects their disinfected state and can be used if needed.
- 10 to 500 ml / h of aerosol generated and brought into contact with the object to be disinfected is 10 to 500 ml / h of aerosol generated and brought into contact with the object to be disinfected.
- the amount can be adapted to the application.
- aerosol quantities of 10 to 50 ml / h are sufficient.
- the duration of disinfection plays a role, as is the case in particular with the disinfection of body parts, it is intended to contact them with a larger amount of disinfectant.
- the method according to the invention is intended to replace the disinfection method known from the prior art by means of a liquid disinfectant dispenser. As a rule, doctors and nursing staff should disinfect their hands when entering and leaving the sickroom.
- the duration required for the disinfection should not exceed 30 seconds, preferably 10 seconds.
- the aerosol is produced in an amount of 400 to 500 ml / h and contacted with the object or body part to be disinfected. This reduces the duration of disinfection to less than 10 seconds.
- the disinfectant is atomized in the preparation of the aerosol to a droplet size with a mean diameter below 10 ⁇ , preferably below 5 ⁇ .
- a suspended aerosol is produced and, on the other hand, it is ensured that the entirety of the aerosol can also reach areas which are difficult to access, such as, in particular, skin or material furrows, and can subsequently disinfect them.
- the device for the purpose of disinfecting medical tools, preferably surgical instruments, dental tools and / or body parts, such as in particular hands and feet further proposed, the device with an application unit for receiving the objects to be disinfected or body parts and contacting with to equip the aerosol.
- a device with a disinfectant tank for providing a disinfectant one with the disinfectant tank line-connected aerosol generating unit for generating an aerosol from the disinfectant, a line connected to the aerosol generating unit ventilation unit for sucking ambient air and for discharging the aerosol from the aerosol generating unit, and a line connected to the aerosol generating unit application unit, which provides a disinfection area in the form of a volume space, said the Voiumenraum has a first opening for introducing the aerosol on the one hand and a second opening for introducing and removing the object to be disinfected and / or body part on the other.
- the device further includes a aerosol generating unit connected to the disinfectant tank for generating an aerosol from the disinfectant.
- the aerosol generating unit has a sputtering membrane. This is preferably designed such that it can oscillate in an adjustable frequency. The frequency is preferably set as a function of the quantity of aerosol to be generated. Further preferably, the frequency can be adjusted depending on the size of the disinfectant droplets to be generated. Preferably, it is provided to allow the sputtering membrane to oscillate at a frequency in the ultrasonic range. As a result, particularly small disinfectant droplets in the range below 10 pm can be generated.
- the aerosol generating unit may have at least two ultrasonic sputtering membranes.
- the aerosol generating unit may have at least two ultrasonic sputtering membranes.
- comparatively large quantities of aerosol can be produced in a short time.
- the minimum duration required for the disinfection can be reduced in an advantageous manner.
- the number of sputtering membranes is not limited and can be varied depending on the size of the room, the amount and / or the objects / body parts to be disinfected and the desired minimum duration.
- the aerosol generating unit has a heating element.
- the aerosol is generated in that by means of the heating element, the disinfectant is evaporated.
- the heating element is designed as an electric heating element, particularly preferably as an electric heating cartridge.
- the volume space is adapted in its dimensions to the objects to be disinfected.
- the disinfection of body parts is not limited to hands.
- a special case arises in particular in the case of "surgical" disinfection, whereby it is provided that not only the hands, but also the arms are at least partially disinfected,
- a volume space corresponding to It is envisaged that the user can insert his arms into the volume space at least to a depth of 60 cm, whereby the volume space is preferably tubular or shaft-shaped and serves to receive the arms of the user Invention also meets the relatively high requirements of a "surgical" disinfection and leads advantageously to a complete disinfection of the particular in terms of germ transmission in surgical procedures exposed body parts.
- the device is advantageously designed for a variety of objects to be disinfected, whereby the disinfection process is improved overall.
- the first opening is formed as a nozzle.
- the inflow velocity of the aerosol is increased in the disinfection area, whereby the distribution of the aerosol in the Disinfection area is improved.
- the disinfecting effect is advantageously further improved.
- the volume space has a multiplicity of first openings.
- the first openings can be distributed uniformly over walls of the volume space. Equally, this means in particular that immediately adjacent first openings are arranged equidistant from each other. As a result, the uniform distribution of the aerosol in the volume space is further improved.
- the first openings are arranged heterogeneously on the walls of the volume space. This results in particular with the special design of the shape of the volume space the possibility to arrange a comparatively large number of first openings in areas to arrange the areas of the object to be disinfected with increased probability of contamination in the immediate vicinity. This ensures that particularly hazardous areas are reliably disinfected. In particular, even if the prescribed minimum period is not met.
- the device further has a control device.
- a control device This serves in particular to control the individual components.
- it can be used to control liquid flows between the reservoir and the disinfectant tank.
- the liquid flow from the disinfectant tank to the aerosol generating unit can be controlled by the control device.
- the control device may be connected to control with pumps and / or valves and / or other flow-regulating devices.
- the provision of a control device advantageously allows an automated operation of the device according to the invention. As a result, in particular the maintenance effort can be reduced and the overall efficiency of the method can be improved.
- the control device can be designed to detect fault conditions.
- the control device is connected to corresponding sensors. These sensors can be preferred in the Individual components can be arranged.
- the control device is connected to the above-described error output unit for this purpose. Previously detected error conditions can thereby be reported to the error output unit, which displays them in such a case.
- the aerosol flow from the aerosol generating unit to the application unit can be controlled by the control device.
- the control device is preferably connected to the ventilation unit and the aerosol generating unit control technology.
- the control device is connected to a control unit control technology.
- the operating unit is preferably designed to be operable by the user.
- the disinfection process can be activated by means of the operating unit. It has for this purpose a user-side actu bar trained switch.
- the operating unit preferably has a sensor.
- the sensor is used for automated activation of the disinfection process.
- the disinfection is started by the control device as soon as the sensors have detected an object to be disinfected within a predeterminable range.
- the sensors, ais light sensors, thermal sensors and / or touch sensor may be formed.
- At least one light sensor is arranged within the application unit in the region of the second opening, so that the introduction of an object to be disinfected into the application unit is detected by the sensor.
- a touch sensor preferably a pressure sensor
- the disinfection is activated by means of the pressure sensor.
- the light sensor it is checked whether objects to be disinfected are in the disinfection area.
- the disinfection is started only if objects are also in the disinfection area.
- the user on the Error dispensing unit an error message is issued in the case of hand disinfection, it is provided in this preferred case, to arrange the pressure sensor in an area of the device, which corresponds to the position of the knees or feet of an average user.
- the user can introduce his hands to be disinfected in the disinfection area, the hands are detected by the light sensor and press the pressure sensor by means of a foot or a knee.
- foot disinfection on the other hand, it is intended to activate the pressure sensor by hand and to detect the proper positioning of the feet by means of the light sensor. The arrangement of the sensors results accordingly.
- the control device detects the activation time of the disinfection to the second, preferably millisecond accurate, and calculates by means of a predetermined minimum duration to the second, preferably millisecond accurate, an end time for disinfection.
- different values for the minimum duration to be used are stored in the control device as a function of the object to be disinfected.
- the user can retrieve and select the respective minimum duration via the operating unit.
- the operating unit preferably has a touch display for this purpose.
- the control device is preferably connected in terms of control technology with suitable signal units, such as, in particular, a loudspeaker for generating an acoustic signal and / or an LED for generating a visual signal.
- the device according to the invention can be operated simultaneously both for soil disinfection and for disinfection.
- the generated aerosol stream is preferably partially introduced into the space to be sterilized and partially fed to the application unit.
- the aerosol is preferably produced in the concentration required for spatial germination.
- the aerosol is then concentrated in the application unit itself and / or in an intermediate concentration unit to the preferred concentration for disinfection.
- the device has either two separate aerosol generating units or an aerosol unit with line separate from each other areas for generating the aerosol for the spatial disinfection on the one hand and the generation of the aerosol for disinfection on the other.
- the disinfectant is partially supplied to the respective aerosol generating units or the separate areas.
- Both the ratio of the aerosol stream according to the first alternative and the disinfectant streams according to the second alternative can be set and controlled via the control device.
- FIG. 1 shows a device according to the invention for carrying out the method according to the invention according to a first embodiment in a schematic representation.
- FIG. 2 shows a device according to the invention for carrying out the method according to the invention in a second embodiment in a schematic representation.
- FIG. 1 shows a device 1 according to the invention with a storage container 2.
- the storage container 2 is connected to the disinfectant tank 3 by piping.
- the connection of the disinfectant tank 3 and the reservoir 2 is realized in the present example with the interposition of a peristaltic pump 5.
- the disinfectant tank 3 has a fill level sensor 4.
- the fill level sensor 4 is connected with the peristaltic pump 5 in terms of control technology. In this way, when falling below a predetermined level in the disinfectant tank 3 automatically disinfectant from the reservoir 2 spent in the disinfectant tank 3. As a result, a continuous operation is advantageously made possible.
- the disinfectant is formed in this embodiment as an aqueous solution. It therefore consists of 97% by weight of demineralized water, 2.7% by weight. Hydrogen peroxide and 0.3% by weight of coconut oil-based surfactants. Such an active ingredient combination has proven to be particularly effective in terms of effectiveness against common germs, so that comparatively low concentrations lead to a substantially complete sterilization.
- the aforementioned disinfecting solution has a comparatively broad anti-microbial spectrum. It has been found to be equally effective against bacteria, viruses, spores and fungi.
- the use of hydrogen peroxide causes an air freshening due to the formation of oxygen, which is perceived by persons present as pleasant.
- the disinfectant tank 3 is conductively connected to an ozone generating unit 6.
- the ozone generating unit 6 is presently designed in the form of an ozone candle.
- the ozone produced in the ozone candle is introduced into the disinfectant solution.
- the ozone formed dissolves at least partially in the disinfectant.
- the thus modified disinfectant is supplied to the aerosol generating unit 7.
- the aerosol generating unit 7 has a sputtering membrane (not shown).
- the sputtering membrane oscillates at a frequency in the ultrasonic range. As a result, disinfectant droplets can be produced with a diameter of 3 pm.
- Such a droplet size is particularly advantageous in terms of the levitation ability of the aerosol.
- Such an aerosol also reaches areas of the space to be sterilized, which are relatively far away from the device 1 without first sinking.
- rough, porous, in particular textile surfaces, which are not accessible to conventional disinfection processes, can be sterilized particularly effectively by means of such an aerosol. This is due in particular to the advantageous droplet size, advantageous material handling of the aerosol droplets.
- the aerosol generating unit 7 is conductively connected to a ventilation unit 8.
- the ventilation unit 8 draws in a room air surrounding the device for the purpose of aerosol generation.
- the room air is moved past the sputtering membrane, and thus serves as a carrier medium for the disinfectant.
- the microdroplets produced on the sputtering membrane are introduced into the airflow for this purpose.
- the generated aerosol is discharged from the device.
- the discharge can according to the invention either directly in the sterilizing space.
- the device 1 can be placed in the space to be sterilized or the area to be sterilized.
- the device 1 is made mobile to sterilize various rooms or areas of space as desired or necessary.
- the device comprises 1 rollers.
- the aerosol can be indirectly introduced into the space to be sterilized.
- the device 1 is arranged in an existing ventilation system of a building, which connects a plurality of rooms with each other in order to sterilize as many rooms as possible.
- the present in such a ventilation system air flow flows around the device. It serves advantageously as a carrier medium for the disinfectant in the aerosol.
- the device has an error output unit, not shown.
- the error output unit is presently designed as an LED field. Faults of the disinfectant tank are indicated by a green LED. Errors of the aerosol generating unit are indicated by a red LED. Faults of the ventilation unit are indicated by a yellow LED. Vorteifhaftide this leads to an overall simplification of maintenance and, where appropriate, the repair of the device 1, since sources of error can be detected and displayed directly.
- FIG. 2 shows a device 1 according to the invention with a storage container 2.
- the storage container 2 is connected in line with the disinfectant tank 3.
- the connection of the disinfectant tank 3 and the reservoir 2 is realized in the present example with the interposition of a peristaltic pump 5.
- the disinfectant tank 3 has a level sensor 4.
- the level sensor 4 is connected to the peristaltic pump 5 in terms of control technology. In this way, when falling below a predetermined level in the disinfectant tank 3 automatically disinfectant from the reservoir 2 spent in the disinfectant tank 3. As a result, a continuous operation is advantageously made possible.
- the disinfection center! is formed in this embodiment as an aqueous solution. Accordingly, it consists of 97% by weight of deionized water, 2.7% by weight of hydrogen peroxide and 0.3% by weight of coconut oil-based surfactants.
- Such Active ingredient combination has proven to be particularly effective in terms of effectiveness against common germs, so that comparatively low concentrations lead to a substantially complete sterilization.
- the aforementioned disinfecting solution has a comparatively broad anti-microbial spectrum. It has been found that it is equally effective against bacteria, viruses, spores and fungi and in the concentration of the invention for the disinfection of medical tools, preferably surgical instruments, dental tools and / or covered and uncovered body parts, especially hands and feet suitable is.
- the disinfectant tank 3 is conductively connected to an ozone generating unit 6.
- the ozone generating unit 6 is presently designed in the form of an ozone candle.
- the ozone produced in the ozone candle is introduced into the disinfectant solution.
- the ozone formed dissolves at least partially in the disinfectant.
- the thus modified disinfectant is supplied to the aerosol generating unit 7.
- the aerosol generating unit 7 has a sputtering membrane (not shown).
- the atomizing membrane oscillates with a frequency in the ultrasonic range.
- disinfectant droplets can be produced with a diameter of 3 ⁇ .
- the aerosol generating unit 7 is conductively connected to a ventilation unit 8.
- the ventilation unit 8 draws in a room air surrounding the device for the purpose of aerosol generation.
- the room air is moved past the sputtering membrane, and thus serves as a carrier medium for the disinfectant.
- the microdroplets produced on the sputtering membrane are inserted into the Introduced air flow.
- the aerosol is produced here with a concentration of 0.6 ml / m 3 .
- the generated aerosol is fed to an application unit 9.
- the aerosol generating unit 7 and the application unit 9 are interconnected in terms of line technology.
- the application unit 9 provides a disinfection area in the form of a volume space.
- the disinfection area has a multiplicity of first openings for introducing the aerosol into the disinfection area, which are arranged uniformly over its inside. Furthermore, the disinfection area has a second opening for introducing the objects to be disinfected into the disinfection area.
- the application unit 9 is designed as a hand disinfection unit.
- the device 1 has a control device, not shown, which is mechanically connected to a control unit for activating the disinfection process.
- the operating unit is equipped with a pressure sensor and a light sensor.
- the pressure sensor is arranged at the user's external wall of the device when the device is used as intended, at the knee height of an average user.
- the disinfection preferably the introduction of the aerosol into the disinfectant area is started, provided that the light sensor detects the proper positioning of the hands within the disinfection area.
- the controller now detects the start time. In the present case, a disinfection period of 20 seconds is stored in the control device.
- the control device calculates an end time for the disinfection. If this is achieved, the disinfection, preferably the introduction of the aerosol is stopped in the disinfection area. Furthermore, the user is informed about the completion of the disinfection by means of a suitable signal, in the present case an acoustic signal.
- the device has an error output unit, not shown.
- the error output unit is presently designed as an LED field. Faults of the disinfectant tank are indicated by a green LED. Errors of the aerosol generating unit are indicated by a red LED. Faults of the ventilation unit are indicated by a yellow LED.
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- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
La présente invention concerne un désinfectant constitué d'une solution de désinfectant aqueuse contenant un oxydant sous forme de H202 et un tensioactif végétal.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14199005.1A EP3034099B1 (fr) | 2014-12-18 | 2014-12-18 | Méthode et système de sterilisation d'habitations avec du peroxyde d'hydrogène et un tensioactif |
| EP14199005.1 | 2014-12-18 | ||
| EP15181083.5 | 2015-08-14 | ||
| EP15181083.5A EP3130358A1 (fr) | 2015-08-14 | 2015-08-14 | Procede et systeme de desinfection d'instruments medicaux et de parties du corps |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2016096818A1 true WO2016096818A1 (fr) | 2016-06-23 |
Family
ID=54849940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2015/079740 Ceased WO2016096818A1 (fr) | 2014-12-18 | 2015-12-15 | Désinfectant contenant du peroxyde d'hydrogène et un tensioactif végétal, et procédé d'aseptisation |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2016096818A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018011501A1 (fr) * | 2016-07-11 | 2018-01-18 | Laboratoires Anios | Dispositif de nébulisation d'un produit liquide |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1375634A1 (fr) * | 2002-06-26 | 2004-01-02 | Tevan B.V. | Compositions aqueuses désinfectantes à effet bactéricide rapide |
| EP1382666A1 (fr) * | 2002-06-21 | 2004-01-21 | Tevan B.V. | Compositions aqueuses désinfectantes à effet bactéricide rapide |
| US20050152991A1 (en) * | 2004-01-09 | 2005-07-14 | Ecolab Inc. | Medium chain peroxycarboxylic acid compositions |
| US20080267900A1 (en) * | 2005-03-23 | 2008-10-30 | Basf Aktiengesellschaft | Surface Treatment |
| US20110058986A1 (en) * | 2008-08-20 | 2011-03-10 | Sanyo Electric Co., Ltd. | Isolator |
-
2015
- 2015-12-15 WO PCT/EP2015/079740 patent/WO2016096818A1/fr not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1382666A1 (fr) * | 2002-06-21 | 2004-01-21 | Tevan B.V. | Compositions aqueuses désinfectantes à effet bactéricide rapide |
| EP1375634A1 (fr) * | 2002-06-26 | 2004-01-02 | Tevan B.V. | Compositions aqueuses désinfectantes à effet bactéricide rapide |
| US20050152991A1 (en) * | 2004-01-09 | 2005-07-14 | Ecolab Inc. | Medium chain peroxycarboxylic acid compositions |
| US20080267900A1 (en) * | 2005-03-23 | 2008-10-30 | Basf Aktiengesellschaft | Surface Treatment |
| US20110058986A1 (en) * | 2008-08-20 | 2011-03-10 | Sanyo Electric Co., Ltd. | Isolator |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018011501A1 (fr) * | 2016-07-11 | 2018-01-18 | Laboratoires Anios | Dispositif de nébulisation d'un produit liquide |
| TWI790205B (zh) * | 2016-07-11 | 2023-01-21 | 法商阿尼歐斯實驗股份有限公司 | 用於空氣消毒的霧化裝置、其使用方法及其用途 |
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