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WO2016086022A3 - Heteroaromatic imidazolyl compounds and methods for treating cancer - Google Patents

Heteroaromatic imidazolyl compounds and methods for treating cancer Download PDF

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Publication number
WO2016086022A3
WO2016086022A3 PCT/US2015/062486 US2015062486W WO2016086022A3 WO 2016086022 A3 WO2016086022 A3 WO 2016086022A3 US 2015062486 W US2015062486 W US 2015062486W WO 2016086022 A3 WO2016086022 A3 WO 2016086022A3
Authority
WO
WIPO (PCT)
Prior art keywords
heteroaromatic
methods
treating cancer
compounds
imidazolyl compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2015/062486
Other languages
French (fr)
Other versions
WO2016086022A2 (en
Inventor
Kandalam V. RAMANUJACHARY
Subash C. JONNALAGADDA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pelthos Therapeutics Inc
Original Assignee
Channel Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Channel Therapeutics Inc filed Critical Channel Therapeutics Inc
Publication of WO2016086022A2 publication Critical patent/WO2016086022A2/en
Publication of WO2016086022A3 publication Critical patent/WO2016086022A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Provided herein are heteroaromatic imidazolyl compounds, compositions comprising such compounds, and related methods of making and using the compounds, e.g., the compounds are useful for treating diseases such as cancer.
PCT/US2015/062486 2014-11-26 2015-11-24 Heteroaromatic imidazolyl compounds and methods for treating cancer Ceased WO2016086022A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462085148P 2014-11-26 2014-11-26
US62/085,148 2014-11-26

Publications (2)

Publication Number Publication Date
WO2016086022A2 WO2016086022A2 (en) 2016-06-02
WO2016086022A3 true WO2016086022A3 (en) 2016-10-13

Family

ID=56075127

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2015/062486 Ceased WO2016086022A2 (en) 2014-11-26 2015-11-24 Heteroaromatic imidazolyl compounds and methods for treating cancer

Country Status (1)

Country Link
WO (1) WO2016086022A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106632331A (en) * 2016-12-19 2017-05-10 盐城师范学院 Probe for detecting ketoacidosis factors of diabetes and synthesizing and using method thereof
CN115266983B (en) * 2022-07-29 2023-11-17 最高人民检察院检察技术信息研究中心 Method for measuring antifungal drugs in antibacterial agent of antibacterial product by using gas chromatography mass spectrometry

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070123553A1 (en) * 2003-11-14 2007-05-31 Lorus Therapeutics Inc. Aryl imidazoles and their use as anti-cancer agents
CN101735217A (en) * 2009-12-15 2010-06-16 广东药学院 Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug
US20110152337A1 (en) * 2002-08-19 2011-06-23 Lorus Therapeutics Inc. 2,4,5-trisubstituted imidazoles and their use as anti-microbial agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110152337A1 (en) * 2002-08-19 2011-06-23 Lorus Therapeutics Inc. 2,4,5-trisubstituted imidazoles and their use as anti-microbial agents
US20070123553A1 (en) * 2003-11-14 2007-05-31 Lorus Therapeutics Inc. Aryl imidazoles and their use as anti-cancer agents
CN101735217A (en) * 2009-12-15 2010-06-16 广东药学院 Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SERGEEVA, N. N. ET AL.: "Synthesis and evaluation of the europium III and zinc II complexes as luminescent bioprobes in high content cell -imaging analysis", JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 105, no. 12, 2011, pages 1589 - 1595, XP028336561 *
SHI, S. ET AL.: "Targeting Human Telomeric G-Quadruplex DNA and Inhibition of Telomerase Activity With [(dmb)2Ru(obip)Ru(dmb)2]4+", PLOS ONE, vol. 8, no. 12, 2013, pages 1 - 15, XP055320038 *

Also Published As

Publication number Publication date
WO2016086022A2 (en) 2016-06-02

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