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WO2016043683A1 - Dispositif de numération globulaire du sang - Google Patents

Dispositif de numération globulaire du sang Download PDF

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Publication number
WO2016043683A1
WO2016043683A1 PCT/TR2015/050103 TR2015050103W WO2016043683A1 WO 2016043683 A1 WO2016043683 A1 WO 2016043683A1 TR 2015050103 W TR2015050103 W TR 2015050103W WO 2016043683 A1 WO2016043683 A1 WO 2016043683A1
Authority
WO
WIPO (PCT)
Prior art keywords
lymphocyte
ratio
parameters
blood count
count device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/TR2015/050103
Other languages
English (en)
Inventor
Ihsan Hakki CIFTCI
Mehmet KOROGLU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2016043683A1 publication Critical patent/WO2016043683A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/018—Platelets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data

Definitions

  • the present invention relates to blood count devices used for measuring pluralities of parameters in blood samples for diagnosis of diseases in healthcare field.
  • the present invention relates to a blood count device, for eliminating the above mentioned disadvantages and for bringing new advantages to the related technical field.
  • the main object of the present invention is to provide a blood count device providing the NLR, NMR, LMR, PLR parameters.
  • the present method is a blood count device in order to provide submission of pluralities of parameters as a report as a result of examination of the blood samples.
  • the present invention is characterized by comprising a processor unit which uses the information and formula provided in a memory unit and which calculates the neutrophil/lymphocyte ratio (NLR), neutrophil/monocyte ratio (NMR), lymphocyte/monocyte ratio (LMR) and thrombocyte/lymphocyte ratio (PLR); and an output unit presenting the results to a user.
  • NLR neutrophil/lymphocyte ratio
  • NMR neutrophil/monocyte ratio
  • LMR lymphocyte/monocyte ratio
  • PLR thrombocyte/lymphocyte ratio
  • Figure 1 a representative schematic view of the operation system of the subject matter blood count device is given.
  • the subject matter blood count device comprises a processor unit (20) in order to process the parameters obtained from the blood sample according to the schematic view given in Figure 1.
  • Said processor unit (20) presents the obtained parameters to the user through an output unit (30).
  • the neutrophil, lymphocyte, monocyte, thrombocyte parameters are determined.
  • Said processor unit (20) calculates the NLR, NMR, LMR, PLR parameters in the light of the information and formulas received from a memory unit (10). Afterwards, the new parameters, which have been obtained, are presented to the user through the output unit (30) together with the other parameters.
  • NLR, NMR, LMR, PLR parameters are calculated by the processor unit (20) by using the ratios of:
  • NLR neutrophil/lymphocyte
  • NMR neutrophil/monocyte
  • LMR lymphocyte/monocyte

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne un dispositif de numération globulaire du sang afin de présenter plusieurs paramètres sous la forme d'un rapport en tant que résultat d'un examen des échantillons de sang, caractérisé en ce qu'il comprend une unité de processeur (20) qui utilise les informations et la formule prévues dans une unité de mémoire (10) et qui calcule le rapport neutrophile/lymphocyte (NLR), le rapport neutrophile/monocyte (NMR), le rapport lymphocyte/monocyte (LMR) et le rapport thrombocyte/lymphocyte (PLR); et une unité de sortie (30) présentant les résultats à un utilisateur.
PCT/TR2015/050103 2014-09-18 2015-09-15 Dispositif de numération globulaire du sang Ceased WO2016043683A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2014/10991 2014-09-18
TR201410991 2014-09-18

Publications (1)

Publication Number Publication Date
WO2016043683A1 true WO2016043683A1 (fr) 2016-03-24

Family

ID=54478942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2015/050103 Ceased WO2016043683A1 (fr) 2014-09-18 2015-09-15 Dispositif de numération globulaire du sang

Country Status (1)

Country Link
WO (1) WO2016043683A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378633A (en) * 1992-02-07 1995-01-03 Sequoia-Turner Corporation, A Corp. Of Ca Method for accurately enumerating and sensitively qualifying heterogenous cell populations in cytolytic processing conditions
WO2003001205A1 (fr) * 2001-06-25 2003-01-03 Pharmacia Diagnostics Ab Procede d'evaluation d'une quantite de types de cellules specifiques
US6524858B1 (en) * 1999-03-31 2003-02-25 Bayer Corporation Single channel, single dilution detection method for the identification and quantification of blood cells and platelets in a whole blood sample using an automated hematology analyzer
US20050182568A1 (en) * 2001-09-11 2005-08-18 Christian Duraffourd Method for evaluating a patients biological condition
US20110053212A1 (en) * 2008-05-09 2011-03-03 Sysmex Corporation Blood analyzer, blood analysis method, hemolytic agent and staining agent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378633A (en) * 1992-02-07 1995-01-03 Sequoia-Turner Corporation, A Corp. Of Ca Method for accurately enumerating and sensitively qualifying heterogenous cell populations in cytolytic processing conditions
US6524858B1 (en) * 1999-03-31 2003-02-25 Bayer Corporation Single channel, single dilution detection method for the identification and quantification of blood cells and platelets in a whole blood sample using an automated hematology analyzer
WO2003001205A1 (fr) * 2001-06-25 2003-01-03 Pharmacia Diagnostics Ab Procede d'evaluation d'une quantite de types de cellules specifiques
US20050182568A1 (en) * 2001-09-11 2005-08-18 Christian Duraffourd Method for evaluating a patients biological condition
US20110053212A1 (en) * 2008-05-09 2011-03-03 Sysmex Corporation Blood analyzer, blood analysis method, hemolytic agent and staining agent

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