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WO2015103614A3 - Système d'imagerie optique en infrarouges proches pour l'imagerie hémodynamique, le contrôle du pouls et de cartographie de caractéristiques spatio-temporelles - Google Patents

Système d'imagerie optique en infrarouges proches pour l'imagerie hémodynamique, le contrôle du pouls et de cartographie de caractéristiques spatio-temporelles Download PDF

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Publication number
WO2015103614A3
WO2015103614A3 PCT/US2015/010330 US2015010330W WO2015103614A3 WO 2015103614 A3 WO2015103614 A3 WO 2015103614A3 US 2015010330 W US2015010330 W US 2015010330W WO 2015103614 A3 WO2015103614 A3 WO 2015103614A3
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WO
WIPO (PCT)
Prior art keywords
nir
imaged
tissue
tissue sample
spatio
Prior art date
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Ceased
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PCT/US2015/010330
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WO2015103614A2 (fr
Inventor
Anuradha Godavarty
Youngjin JUNG
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Florida International University FIU
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Florida International University FIU
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Priority to EP15733318.8A priority Critical patent/EP3091897A4/fr
Publication of WO2015103614A2 publication Critical patent/WO2015103614A2/fr
Publication of WO2015103614A3 publication Critical patent/WO2015103614A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02416—Measuring pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/065—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0264—Electrical interface; User interface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0272—Handheld
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G01J3/108—Arrangements of light sources specially adapted for spectrometry or colorimetry for measurement in the infrared range
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0431—Portable apparatus, e.g. comprising a handle or case
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3155—Measuring in two spectral ranges, e.g. UV and visible
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Human Computer Interaction (AREA)
  • Optics & Photonics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Artificial Intelligence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

La présente invention concerne des techniques d'obtention d'images de tissus biologiques dans le but de déterminer une information biologique sur l'échantillon de tissu soumis à l'imagerie, comme des changements de concentrations d'hémoglobine, du débit sanguin (pouls) et/ou des caractéristiques spatio-temporelles. Des modes de réalisation comprennent l'éclairage de l'échantillon de tissu par de la lumière dans le spectre des infrarouges proches (IRP), qui est minimalement absorbée mais diffusée dans l'échantillon de tissu. En détectant la lumière IRP qui est atténuée dans, transmise par et/ou réfléchie par le tissu soumis à l'imagerie, les signaux d'intensité IRP obtenus peuvent être ensuite analysés pour obtenir ces données. Des modes de réalisation comprennent l'utilisation de multiples sources d'IRP ayant diverses longueurs d'onde pour déterminer des changements des concentrations d'oxy- et de désoxy-hémoglobine de la région de tissu soumise à l'imagerie. L'échantillon de tissu peut être soumis à l'imagerie pendant une période de temps, et les images IRP peuvent être visualisées en statique ou en temps réel après que des analyses post-traitement aient été effectuées.
PCT/US2015/010330 2014-01-06 2015-01-06 Système d'imagerie optique en infrarouges proches pour l'imagerie hémodynamique, le contrôle du pouls et de cartographie de caractéristiques spatio-temporelles Ceased WO2015103614A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15733318.8A EP3091897A4 (fr) 2014-01-06 2015-01-06 Système d'imagerie optique en infrarouges proches pour l'imagerie hémodynamique, le contrôle du pouls et de cartographie de caractéristiques spatio-temporelles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461924049P 2014-01-06 2014-01-06
US61/924,049 2014-01-06

Publications (2)

Publication Number Publication Date
WO2015103614A2 WO2015103614A2 (fr) 2015-07-09
WO2015103614A3 true WO2015103614A3 (fr) 2015-08-20

Family

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PCT/US2015/010330 Ceased WO2015103614A2 (fr) 2014-01-06 2015-01-06 Système d'imagerie optique en infrarouges proches pour l'imagerie hémodynamique, le contrôle du pouls et de cartographie de caractéristiques spatio-temporelles

Country Status (3)

Country Link
US (2) US10258242B2 (fr)
EP (1) EP3091897A4 (fr)
WO (1) WO2015103614A2 (fr)

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Also Published As

Publication number Publication date
US20150190061A1 (en) 2015-07-09
US10258242B2 (en) 2019-04-16
WO2015103614A2 (fr) 2015-07-09
EP3091897A2 (fr) 2016-11-16
US20190183357A1 (en) 2019-06-20
EP3091897A4 (fr) 2017-12-27
US11330985B2 (en) 2022-05-17

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