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WO2015167194A1 - Dispositif de commande permettant d'augmenter la pression sanguine d'un sinus coronaire afin de traiter une angine de poitrine - Google Patents

Dispositif de commande permettant d'augmenter la pression sanguine d'un sinus coronaire afin de traiter une angine de poitrine Download PDF

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Publication number
WO2015167194A1
WO2015167194A1 PCT/KR2015/004204 KR2015004204W WO2015167194A1 WO 2015167194 A1 WO2015167194 A1 WO 2015167194A1 KR 2015004204 W KR2015004204 W KR 2015004204W WO 2015167194 A1 WO2015167194 A1 WO 2015167194A1
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WIPO (PCT)
Prior art keywords
coronary sinus
tube
blood pressure
angina
increasing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2015/004204
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English (en)
Korean (ko)
Inventor
김준홍
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Tau PNU Medical Co Ltd
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Tau PNU Medical Co Ltd
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Filing date
Publication date
Application filed by Tau PNU Medical Co Ltd filed Critical Tau PNU Medical Co Ltd
Publication of WO2015167194A1 publication Critical patent/WO2015167194A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
    • A61B2576/023—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the heart

Definitions

  • the present invention relates to a surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, and more particularly to the procedure for treating angina by raising the blood pressure of the coronary sinus to solve the shortage of blood flow in the coronary artery that causes the angina It relates to a device for.
  • the heart is an organ that acts as a blood pump. To operate this muscle pump (heart) requires a valve that allows blood flow to flow in a constant direction rather than backflow.
  • the heart has four rooms, two atriums and two ventricles, which are connected to four vessels: the aorta, veins, pulmonary arteries, and pulmonary veins.
  • the valve between the left atrium and the left ventricle is the mitral valve (MV)
  • the valve between the right atrium and the right ventricle is the tricuspid valve (TV)
  • the valve between the left ventricle and the aorta is the aortic valve
  • the valve between the pulmonary arteries is the pulmonary valve (PV).
  • the heart receives and acts on oxygen and nutrients by three cardiovascular vessels (coronary artery).
  • Acute or chronic stenosis in any of the three coronary arteries due to atherosclerosis, thrombosis, vasoconstriction and spasm (reduction of diameters of blood vessels due to contractions, etc.)
  • the oxygen and nutrient supply is drastically reduced as the blood supply to all or part of the heart decreases, leading to secondary ischemia of the heart muscle. This situation is called "angina”.
  • angina pectoris is a state in which a sufficient amount of blood flow to the myocardium due to a lack of coronary blood supply is manifested as chest pain and hypoventricular function.
  • ischemic cardiomyopathy results in ischemic cardiomyopathy, which leads to left ventricular dilatation, which in turn leads to functional "mitral valve reflux".
  • mitral valve reflux the rate of blood flow to the myocardium due to a lack of coronary blood supply.
  • Heart valve disease can be divided into two types: a disease that causes blood to leak completely (closure, regurgitation) and a disease that does not open completely when the valve needs to be closed (stenosis).
  • Mitral regurgitation is a valve between the left atrium and the left ventricle that does not close completely when the valve needs to close, causing blood to flow back, causing the heart to lose heart function and eventually leading to heart failure. Disease.
  • mitral cerclage coronary sinus annuloplasty (MVA) in an international paper, which indicated a circular pressure around the mitral annulus (MA). It was proved that the treatment effect is excellent because it can be added.
  • the contents of the paper have been filed in international patent applications (International Application No .: PCT / US2007 / 023836) and are now published internationally by the International Bureau (International Publication No. WO2008 / 060553). Further, the present inventor has devised and registered a CSTV tube (coronary sinus and three thousand valve tissue protection mechanism) surrounding the circle large yarn (Korean Patent Registration No. 1116867 (2012.02.08 registration)).
  • An object of the present invention is to provide a surgical device for treating angina by raising the blood pressure of the coronary sinus to resolve the lack of blood flow in the coronary artery, which is the cause of angina.
  • the present invention is to achieve the above object, according to a preferred embodiment of the present invention, the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, coronary vein tube 12 is inserted into the coronary sinus, Three thousand valve tube 14 is inserted between the three thousand valve and the ventricular septum, and the tubular venous sinus tube and the three thousand valve tube is extended to each other and is fixed to each other.
  • one side of the tubular sinus tube 12 is characterized in that the projection 20 is formed on the outside of the tube.
  • the tubular sinus tube 12 is characterized in that it has a tapered form that the size of the outer diameter decreases toward the end.
  • the tubular sinus tube 12 is characterized in that the size of the outer diameter of the coronary sinus inlet portion 22 is larger than the size of the outer diameter of the tube end portion 24.
  • the distal end of the tube 12 for coronary sinus is characterized by having a tapered surface 26.
  • the surgical device of the present invention can increase the blood pressure of the coronary sinus by the tube for coronary sinus, which is inserted into the coronary sinus, and consequently can be used as a tool for treating angina.
  • the surgical device of the present invention can be easily inserted into the heart, the main part of the human body, the structure is simple, the method of treatment is simple, and many people suffering from angina pectoris to receive the spotlight as a treatment tool harmless to the human body It is expected to be.
  • FIG. 1 shows a surgical device for increasing the blood pressure of the coronary sinus for treating angina, in accordance with a preferred embodiment of the present invention.
  • FIGS. 2-5 show multiple embodiments of a coronary sinus tube of a surgical device for increasing the blood pressure of a coronary sinus for treating angina, according to a preferred embodiment of the present invention.
  • FIG. 1 is a view showing a surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, according to a preferred embodiment of the present invention.
  • the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina of the present invention is a coronary sinus tube 12 is inserted into the coronary venous sinus, three thousand valves and three thousand valve tube inserted between the ventricular septum (14), and the tubular sinus tube and the three thousand valve tube extends each of the extension portion 16 is fixed to each other.
  • the surgical device of the present invention is basically for increasing the coronary sinus pressure for the treatment of angina, and the coronary sinus tube 12 inserted into the coronary sinus corresponds to a portion for increasing the coronary sinus pressure.
  • Coronary sinus is a large vein that extends from the posterior side of the heart along the coronary cortex at the border of the atrium and ventricles, where venous blood, distributed by the coronary artery, finally collects and enters the right atrium.
  • the tubular sinus tube 12 of the surgical device of the present invention is inserted through the coronary sinus inlet, three thousand valve tube 14 is inserted between the three thousand valve and ventricular septum.
  • Coronary sinus tube (CS tube, 12) is named in the sense of the tube (tube) that is inserted into the coronary sinus (coronary sinus), TV tube (14) is inserted into the three thousand valve (tricuspid valve) It is named in the sense that the tube (tube), the surgical device of the present invention will be named 'CSTV tube' because it has a CS tube and a TV tube.
  • Coronary sinus tube (CS tube, 12) and three thousand valve tube (TV tube, 14) will be a tube that is harmless to the human body because it is inserted into the body, the hollow inside of the tube is formed, of course.
  • the material of the tube is made of silicone, rubber, synthetic resin, etc., and has flexible characteristics.
  • the coronary sinus tube 12 of the surgical device of the present invention When the coronary sinus tube 12 of the surgical device of the present invention is inserted into the coronary sinus, it will be described why it is effective for angina. After 2-4 weeks after the coronary sinus tube 12 of the surgical device of the present invention (CSTV tube) is inserted into the coronary sinus, it is covered with the tissue around the tube 12 for coronary sinus. This naturally leads to partial stenosis of the coronary sinus. As described above in the prior art, artificially inducing stenosis in a portion of the coronary sinus, as the blood pressure of the coronary sinus rises in the ventricular endothelial region is increased compared to the ventricular outer membrane region, the blood supply in the coronary artery This will alleviate the symptoms of angina and help restore ventricular function.
  • the tube for coronary sinus can also be a straight structure, it will be able to further increase the effect through the following various structures.
  • Figure 2 is an example of a coronary sinus tube 12 of the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, the projection 20 is formed structure. That is, Figure 2 shows a structure in which the protrusions 20 are formed in a predetermined portion to the outside of the tubular sinus tube 12. The arrows in FIGS. 2-5 show the direction of blood flow.
  • the reason for having such a structure is to increase the blood pressure flowing through the coronary sinus and to increase the blood flow in the ventricular endothelial region more than the ventricular epithelium region, to maximize the effect of treating angina.
  • FIG. 3 is another example of the coronary sinus tube 12 of the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, the outer diameter of the coronary sinus tube is different. That is, the tubular sinus tube 12 shown in Figure 2 shows a structure having a tapered form that the size of the outer diameter is reduced toward the end.
  • the inner diameter of the coronary sinus is different in size, correspondingly configured to taper the size of the outer diameter of the coronary sinus tube 12, the structure designed to protect the coronary sinus by taking the minimum load on the inner diameter of the coronary sinus something to do.
  • Figure 4 is another example of a coronary sinus tube 12 of the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, the step of the coronary sinus tube as the outer diameter of the coronary sinus tube is different If it is. That is, the tubular sinus tube 12 shown in Figure 2 shows a structure configured such that the size of the outer diameter of the coronary sinus inlet portion 22 is larger than the size of the outer diameter of the tube end portion 24. This is a structure for maximizing the effect of treating angina by increasing the blood pressure flowing to the coronary sinus while protecting the coronary sinus by reducing the load on the coronary sinus as much as possible.
  • FIG. 5 is another example of the coronary sinus tube 12 of the surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, so as to have a tapered surface 26 at the distal end of the tube 12 for coronary sinus
  • One structure is shown. This structure will be more advantageous when the tube for coronary sinus is inserted into the coronary sinus.
  • the present invention relates to a surgical device for increasing the blood pressure of the coronary sinus for the treatment of angina, and more particularly to the procedure for treating angina by raising the blood pressure of the coronary sinus to solve the shortage of blood flow in the coronary artery that causes the angina It is available in the field of device for.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne un dispositif de commande permettant d'augmenter la pression sanguine du sinus coronaire afin de traiter une angine de poitrine et, plus particulièrement, un dispositif de commande permettant de traiter une angine de poitrine en augmentant la pression sanguine du sinus coronaire afin de pallier une diminution de l'écoulement sanguin vers une artère coronaire, qui est la cause d'une angine de poitrine. Selon un mode de réalisation préféré de la présente invention, le dispositif de commande permettant d'augmenter la pression sanguine du sinus coronaire afin de traiter une angine de poitrine comprend : un tube (12) de sinus coronaire destiné à être inséré dans le sinus coronaire ; un tube (14) de valvule tricuspide destiné à être inséré entre la valvule tricuspide et la cloison interventriculaire ; et une partie d'extension (16) permettant au tube de sinus coronaire et au tube de valvule tricuspide d'être respectivement étendus pour être fixés et accouplés l'un à l'autre.
PCT/KR2015/004204 2014-04-30 2015-04-28 Dispositif de commande permettant d'augmenter la pression sanguine d'un sinus coronaire afin de traiter une angine de poitrine Ceased WO2015167194A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140052646A KR20150125371A (ko) 2014-04-30 2014-04-30 협심증 치료를 위해 관상정맥동의 혈압을 높이기 위한 시술용 장치
KR10-2014-0052646 2014-04-30

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WO2015167194A1 true WO2015167194A1 (fr) 2015-11-05

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10433962B2 (en) 2016-05-06 2019-10-08 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US10653513B2 (en) 2017-02-21 2020-05-19 Vascular Dynamics, Inc. Baroreceptor testing prior to implantation methods and apparatus
US11007059B2 (en) 2016-05-06 2021-05-18 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11039923B2 (en) 2016-05-06 2021-06-22 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11259926B2 (en) 2017-08-26 2022-03-01 Transmural Systems Llc Cardiac annuloplasty and pacing procedures, related devices and methods
US11980545B2 (en) 2016-05-06 2024-05-14 Transmural Systems Llc Annuloplasty procedures, related devices and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537909A (ja) * 1999-03-01 2002-11-12 コーアクシア・インコーポレイテッド 大動脈部分閉塞器具および大脳潅流増加方法
KR20110023094A (ko) * 2009-08-28 2011-03-08 김준홍 관상정맥동과 삼천판막의 조직보호기구, 매듭 전달 기구 및 이들을 포함하는 승모판막 서클라지 시술용 장치

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537909A (ja) * 1999-03-01 2002-11-12 コーアクシア・インコーポレイテッド 大動脈部分閉塞器具および大脳潅流増加方法
KR20110023094A (ko) * 2009-08-28 2011-03-08 김준홍 관상정맥동과 삼천판막의 조직보호기구, 매듭 전달 기구 및 이들을 포함하는 승모판막 서클라지 시술용 장치

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHMUEL BANAI ET AL.: "Coronary Sinus Reducer Stent for the Treatment of Chronic Refractory Angina Pectoris", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 49, no. 17, 1 May 2007 (2007-05-01), pages 1783 - 1789, XP022043822, ISSN: 0735-1097 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10433962B2 (en) 2016-05-06 2019-10-08 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11007059B2 (en) 2016-05-06 2021-05-18 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11039923B2 (en) 2016-05-06 2021-06-22 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US11980545B2 (en) 2016-05-06 2024-05-14 Transmural Systems Llc Annuloplasty procedures, related devices and methods
US10653513B2 (en) 2017-02-21 2020-05-19 Vascular Dynamics, Inc. Baroreceptor testing prior to implantation methods and apparatus
US11259926B2 (en) 2017-08-26 2022-03-01 Transmural Systems Llc Cardiac annuloplasty and pacing procedures, related devices and methods

Also Published As

Publication number Publication date
KR20150125371A (ko) 2015-11-09

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