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WO2015165082A1 - Casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche - Google Patents

Casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche Download PDF

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Publication number
WO2015165082A1
WO2015165082A1 PCT/CN2014/076613 CN2014076613W WO2015165082A1 WO 2015165082 A1 WO2015165082 A1 WO 2015165082A1 CN 2014076613 W CN2014076613 W CN 2014076613W WO 2015165082 A1 WO2015165082 A1 WO 2015165082A1
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WO
WIPO (PCT)
Prior art keywords
regular hexagon
probe
hole
brain
infrared spectroscopy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2014/076613
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English (en)
Chinese (zh)
Inventor
李洪谊
徐保磊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenyang Institute of Automation of CAS
Original Assignee
Shenyang Institute of Automation of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenyang Institute of Automation of CAS filed Critical Shenyang Institute of Automation of CAS
Priority to PCT/CN2014/076613 priority Critical patent/WO2015165082A1/fr
Publication of WO2015165082A1 publication Critical patent/WO2015165082A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum

Definitions

  • the invention relates to a helmet for efficiently collecting brain signals by using functional near-infrared spectroscopy technology, and can be used for research in the fields of brain science, cognitive science and brain-computer interface. Background technique
  • neuroscientists are particularly looking forward to direct observations, especially non-invasive observations of the functional activities of the human brain.
  • non-invasive imaging techniques such as Positron Emission Tomography (PET), Functional Magnetic Resonance Imaging (fMRI), Electroencephalograph (EEG) and successful applications in neuroscience , making people's research on advanced brain function into an unprecedented realm.
  • PET Positron Emission Tomography
  • fMRI Functional Magnetic Resonance Imaging
  • EEG Electroencephalograph
  • fMRI Compared to PET and EEG, fMRI gives a more precise structural and functional relationship to the brain.
  • Brain functional imaging technologies such as PET and fMRI have injected powerful power into the development of brain science and cognitive science, but their expensive price severely limits their range of applications; in addition, these two methods have high spatial resolution. However, its time resolution is very low, which also greatly limits its application in brain cognitive science.
  • fNIRS Functional Near Infrared Spectroscopy
  • Hb and HbO are the main absorbing substances, so the change in the intensity of the reflected near-infrared light reflects the change in the concentration of these two hemoglobins.
  • the changes in the concentration of these two hemoglobins are thought to be directly related to brain function activities.
  • fNIRS-based brain functional imaging equipment has become an important tool for research in the fields of brain science, cognitive science, and brain-computer interface.
  • the functional near-infrared spectroscopy helmet is a support platform for near-infrared spectroscopy emission probes and receiving probes, which is critical for the resolution of brain functional imaging.
  • the current position of the near-infrared probe has not yet formed an international standard.
  • Jiang Tianzi et al. [Patent No.: ZL200510055893.0] designed a near-infrared spectrum brain functional imaging helmet with a regular pentagon with a side length of 3 cm and a regular hexagonal near-infrared spectrum brain function imaging helmet with a side length of 3 cm. Stitched together. Geely Army, etc.
  • Patent No.: ZL200510089978.0 invented a positive hexagonal high-resolution near-infrared spectroscopy brain function imaging helmet, but the helmet has poor scalability; at the same time, the high density of the probe will lead to a large increase in measurement cost, which is not conducive to brain science, Application in research such as cognitive science and brain-computer interface. Summary of the invention
  • the present invention provides a helmet for collecting brain signals by cellular near-infrared spectroscopy, which can solve the defect of low density of the lattice alignment probe, and has the advantages of relatively high probe density and flexible expansion.
  • a cellular functional near-infrared spectroscopy brain signal acquisition helmet comprising a flexible material covering the scalp and a probe through hole embedded in the flexible material, the flexible material being included
  • a basic measuring unit of a regular hexagon, a half regular hexagon, and a one-third regular hexagon The apex of the basic measuring unit and the center of the regular hexagon have through holes, and the through holes are fixed with a light source probe and detection. For the probe, the two types of through hole positions are interchangeable.
  • the center point and the six vertices of the basic hexagonal basic measuring unit are the through hole positions; the center point is the light source through hole, and the six vertices are the detector through holes, and the two types of through hole positions are interchangeable.
  • the one-half regular hexagon basic measuring unit is cut by a line connecting two pairs of vertices of a regular hexagon; the midpoint of the connecting line is the center point of the original regular hexagon; the center point and the other four
  • the apex is the through hole position; the center point is the light source through hole, and the other four points are the detector through holes, and the two types of through hole positions can be interchanged.
  • the one-third regular hexagon is determined by three adjacent vertices of a regular hexagon and a center point of a regular hexagon, the center point and the three vertices being through-hole positions; the center point is a light source through hole, and three
  • the apex is the detector via, and the two types of via locations are interchangeable.
  • the flexible material consists solely of the basic measuring unit or consists of a combination of basic measuring units.
  • the flexible material is a complete material consisting of a basic measuring unit or an integral body bonded by a basic measuring unit.
  • a hexagonal honeycomb functional near-infrared measuring brain function helmet is designed, and the helmet is basically composed of a regular hexagon, a half regular hexagon and a one-third regular hexagon.
  • the unit is composed and the expansion is very flexible.
  • the light source and the detector jack are designed on the helmet to obtain higher probe utilization than the lattice arrangement.
  • FIG. 1 is a schematic diagram of a light source probe that emits infrared light and a detector probe that receives infrared light to measure a region of the cerebral cortex;
  • FIG. 2 is a schematic view of a lattice arrangement of a conventional probe;
  • Figure 3 is a schematic view of a one-third regular hexagon basic measuring unit of the present invention.
  • Figure 4 is a schematic view of a basic hexagonal basic measuring unit of the present invention.
  • Figure 5 is a schematic view showing a basic hexagonal basic measuring unit and a 6-channel small configuration of the present invention
  • Figure 6 is a schematic illustration of a typical 30-channel mid-range configuration of the present invention
  • Figure 7 is a schematic illustration of a typical 60-channel large configuration of the present invention. detailed description
  • Figure 1 shows the schematic diagram of the functional near-infrared brain function measurement.
  • the area detected by the near-infrared probe that emits infrared light and the near-infrared probe that receives the infrared line is mainly located 2 to 3 cm below the center of the two probe connections.
  • the measurement channel is located between the transmitting probe and the receiving probe.
  • Figure 2 shows a conventional array of lattice probes in which the black mark is the light source probe jack, the white mark is the detector probe jack, and the light source jack and detector jack are interchangeable.
  • the lattice arrangement shown in Figure 2 has a total of 24 channels, and the total number of probes transmitted and received is 16.
  • FIG. 4 and FIG. 5 show the basic measuring unit of the cellular functional near-infrared spectroscopy helmet designed by the present invention, wherein the basic measuring unit shown in FIG. 3 is a 1/3 regular hexagon, and the measuring unit shown in FIG. It is a 1/2 regular hexagon, and Figure 5 shows a complete regular hexagon.
  • the six vertices of the regular hexagon and the center position are provided with through holes for the light source probe and the receiver probe, and the positions of the two probes are interchangeable.
  • the basic measuring unit can be used alone or in combination.
  • FIG. 6 is a schematic view showing a typical medium-sized configuration of a honeycomb functional near-infrared spectroscopy helmet designed by the present invention.
  • This configuration uses two basic measuring units: a full regular hexagon and six 1/2 regular hexagons.
  • the black mark in Figure 6 shows the position of the light source probe, and the white mark shows the position of the probe.
  • the positions of the two probes can be interchanged.
  • the configuration has 30 channels and uses 12 source probes and 7 detector probes.
  • FIG. 7 is a schematic view showing a typical large-scale configuration of a honeycomb functional near-infrared spectroscopy helmet designed by the present invention.
  • This configuration uses seven basic hexagonal and six 1/3 regular hexagonal basic measurement units.
  • the black mark in Figure 7 shows the position of the light source probe, and the white mark shows the position of the probe.
  • the positions of the two probes can be interchanged.
  • the configuration has a total of 60 channels, using 24 light source probes and 13 detector probes.
  • the cellular near-infrared spectroscopy acquisition brain signal helmet proposed by the invention is composed of regular hexagons, one-half regular hexagons and one-third regular hexagons according to certain rules, and each unit is arranged according to a specific rule.
  • a through hole is provided to insert the light source probe and the detector probe.
  • the material covering the scalp is chosen to be flexible and can accommodate head sizes of different sizes.
  • the through holes of the present invention are located at the six corners and center points of the regular hexagon.
  • the typical configuration of the present invention can adopt a small configuration in which a hexagon is formed into 6 channels; a medium configuration in which a regular hexagon and a six-half regular hexagon form a 30 channel can also be adopted; A large configuration of 60 channels can be used with seven regular hexagons and six third regular hexagons; it can also be configured arbitrarily according to actual measurement needs.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention concerne un casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche, qui peut être utilisé dans des recherches dans les domaines de la science du cerveau, la science cognitive et des interfaces cerveau-machine et d'autres domaines. Le casque comprend un matériau souple recouvrant un cuir chevelu, et des trous traversants de sonde incorporés dans le matériau souple. Le matériau souple est constitué d'unités de mesure de base dans les formes comprenant des hexagones réguliers, des moitiés d'hexagones réguliers et des tiers d'hexagones réguliers. Un trou traversant est formé au niveau de chaque sommet et au milieu de chaque hexagone régulier de chaque unité de mesure de base. Une sonde de source de lumière et une sonde de détecteur sont fixées dans le trou traversant, et des positions de deux types de trous traversants peuvent être échangées. La constitution à l'aide des unités de base peut être étendue de façon souple. De plus, des prises de source de lumière et de détecteur sont placées dans le casque, ce qui permet d'obtenir un taux d'utilisation de sonde plus élevé que celui dans un agencement en réseau cristallin. Le casque permet d'avoir un choix optimisé de rapport coût-efficacité pour des chercheurs selon des demandes de recherche sur la science du cerveau, la science cognitive et des interfaces cerveau-machine.
PCT/CN2014/076613 2014-04-30 2014-04-30 Casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche Ceased WO2015165082A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2014/076613 WO2015165082A1 (fr) 2014-04-30 2014-04-30 Casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche

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PCT/CN2014/076613 WO2015165082A1 (fr) 2014-04-30 2014-04-30 Casque de collecte de signal cérébral en nid d'abeilles à l'aide d'une spectroscopie fonctionnelle à infrarouge proche

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107951486A (zh) * 2017-12-04 2018-04-24 深圳贝特莱电子科技股份有限公司 一种头戴式干电极脑电信号采集装置
CN111227790A (zh) * 2020-01-08 2020-06-05 北京师范大学 一种基于脑功能区定位的近红外探头排布方法及头帽

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1833605A (zh) * 2005-03-17 2006-09-20 中国科学院自动化研究所 近红外光谱脑功能成像头盔
CN1911168A (zh) * 2005-08-09 2007-02-14 中国科学院自动化研究所 正六边形高分辨率近红外光谱脑功能成像头盔
WO2008005478A2 (fr) * 2006-07-05 2008-01-10 Brainvital Corporation Traitement de troubles neurologiques par stimulation électrique et procédés correspondants
US20120232402A1 (en) * 2011-03-02 2012-09-13 Macfarlane Duncan Functional Near Infrared Spectroscopy Imaging System and Method
US20130256533A1 (en) * 2012-03-30 2013-10-03 Korea Advanced Institute Of Science And Technology Efficient data extraction method for high-temporal-and-spatial- resolution near infrared spectroscopy system
WO2014022925A1 (fr) * 2012-08-10 2014-02-13 Valorisation-Recherche, Limited Partnership Procédé et système d'examen optique d'un tissu d'un sujet

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1833605A (zh) * 2005-03-17 2006-09-20 中国科学院自动化研究所 近红外光谱脑功能成像头盔
CN1911168A (zh) * 2005-08-09 2007-02-14 中国科学院自动化研究所 正六边形高分辨率近红外光谱脑功能成像头盔
WO2008005478A2 (fr) * 2006-07-05 2008-01-10 Brainvital Corporation Traitement de troubles neurologiques par stimulation électrique et procédés correspondants
US20120232402A1 (en) * 2011-03-02 2012-09-13 Macfarlane Duncan Functional Near Infrared Spectroscopy Imaging System and Method
US20130256533A1 (en) * 2012-03-30 2013-10-03 Korea Advanced Institute Of Science And Technology Efficient data extraction method for high-temporal-and-spatial- resolution near infrared spectroscopy system
WO2014022925A1 (fr) * 2012-08-10 2014-02-13 Valorisation-Recherche, Limited Partnership Procédé et système d'examen optique d'un tissu d'un sujet

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107951486A (zh) * 2017-12-04 2018-04-24 深圳贝特莱电子科技股份有限公司 一种头戴式干电极脑电信号采集装置
CN111227790A (zh) * 2020-01-08 2020-06-05 北京师范大学 一种基于脑功能区定位的近红外探头排布方法及头帽

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