WO2015006999A1 - Lacrimal ductile blocking core - Google Patents
Lacrimal ductile blocking core Download PDFInfo
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- WO2015006999A1 WO2015006999A1 PCT/CN2013/080552 CN2013080552W WO2015006999A1 WO 2015006999 A1 WO2015006999 A1 WO 2015006999A1 CN 2013080552 W CN2013080552 W CN 2013080552W WO 2015006999 A1 WO2015006999 A1 WO 2015006999A1
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- core
- lacrimal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00772—Apparatus for restoration of tear ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12159—Solid plugs; being solid before insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12036—Type of occlusion partial occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/0084—Material properties low friction
- A61B2017/00849—Material properties low friction with respect to tissue, e.g. hollow organs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00893—Material properties pharmaceutically effective
Definitions
- the invention relates to the technical field of medical instruments, in particular to a lacrimal canal core for treating dry eye and preventing narrowing of lacrimal passage after acid-base burn.
- Dry eye syndrome refers to symptoms such as decreased tears or decreased function of lacrimal glands causing dry eyes, acid eyes, itchy eyes, photophobia, and decreased vision. It damages the cornea and, in severe cases, corneal softening and perforation.
- the current important method for treating dry eye syndrome is puncture embolization.
- the method is to seal the tear exclusion tube by implanting a lacrimal duct embolization.
- the method preserves the natural tears secreted by the lacrimal passage itself and prolongs the time the tears stay on the surface of the eye.
- neither degradable nor permanent lacrimal plugs can treat dry eye.
- the present invention overcomes the defects of the prior art and provides a lacrimal tube obstruction core, which can not only treat dry eye disease conveniently, safely and stably, but also prevent narrowing of the lacrimal passage after acid-base burn.
- a tear tube small core comprising a core tube, the core tube has a tapered tip at one end, and the other end of the core tube has a core end.
- the head end of the core block has a flat cylindrical shape without an angular shape, and the head end has no angular angle, and the degree of damage to the eye tissue is low.
- the core tube body has a length of 2-20 mm, the diameter of the core tube body is 0.1 to 1 mm, the thickness of the core end of the resistor core is 0.1 to 1 mm, and the diameter of the head end of the resistor core is 0.5 to 1.5 mm. It is suitable for the treatment of lacrimal passages of different patients, and the core tube is long enough. After entering the lacrimal duct, the shape can be deformed with the curvature of the lacrimal duct. Therefore, the tear tube has a strong contact with the lacrimal duct, and thus does not slip into tears. The road is also not easy to blink and fall out, and the position is fixed for a long time.
- the core tube has a length of 4 to 16 mm, the diameter of the core tube is 0.3 to 0.8 mm, the thickness of the core end of the core is 0.3 to 0.8 mm, and the diameter of the head end of the core is 0.7 to 1.0 mm.
- the core tube body and the core end of the core are processed by a medical silica gel material or processed by a polyolefin or a polyester medical polymer material, and the material is non-sticky to the nascent cells and can maintain the lacrimal passage.
- the shape enters, therefore, the proliferating tissue cells after acid-base burn do not adhere to the lacrimal tube and prevent the narrowing of the lacrimal duct.
- the tear-throat block of the material can adsorb drugs and nutritional factors, drugs and Nutritional factors can be applied to the surface of the lacrimal canal, so the effect of treating dry eye is particularly significant.
- the core tube is provided with a cavity, a micro hole is arranged in the core tube body, and a drug or a nutrient factor is placed in the cavity, and the micro hole can be slowly released and then used by the eye. Absorption, can better treat eye acid and alkali burn symptoms and dry eye syndrome.
- the tapered tip has a hollow structure
- the head of the tapered tip is blunt and has an opening
- the core tube body and the head end of the resistance core have a hollow structure
- the tear tube is blocked.
- the hollow tube of the tear duct adopts a hollow structure in order to allow excess tear fluid to flow out of the eye through the hollow structure of the tear duct and prevent the tears in the lacrimal duct from being moderate.
- FIG. 1 is a schematic structural view of a tear canal core of the present invention
- Figure 2 is a side view of Figure 1
- 3 is a schematic structural view of a tear tube small core according to Embodiment 1 of the present invention
- 4 is a schematic structural view of a tear canal core of the second embodiment of the present invention.
- a lacrimal canal core comprises a core preventing tube body 1 having a tapered tip 3 at one end, and the other end of the core preventing tube body 1 has a core preventing head. End 2.
- the head end 2 of the core block has a flat cylindrical shape without an angular shape, and the end portion 2 of the core block has no angular shape, and the degree of damage to the eye tissue cells is low.
- the dry eye When the tear canal of the structure is implanted into the lacrimal duct, the dry eye can be treated conveniently, safely and stably, and the lacrimal passage can be prevented from narrowing after the acid-base burn, and since it has a head end, it can be conveniently
- the tweezers are removed or implanted into the lacrimal passage. Since the core tube 1 is long enough to be deformed after the lacrimal passage is implanted, the shape of the lacrimal tube is deformed by the curvature of the lacrimal duct, so that the lacrimal tube is in firm contact with the lacrimal passage, and thus does not slide down to the lacrimal passage, and is not easily blinked. Out, the position is fixed for a long time.
- the size of the tear tube is suitable for treating different patients:
- the core tube body 1 has a length of 2 mm, the core tube body 1 has a diameter of 0.1 mm, the core end portion 2 has a thickness of 0.1 mm, and the core end portion 2 has a diameter of 0.5 mm.
- a patient with dry eye syndrome recovers 28 days after using a tear tube of this size every day.
- the core tube body 1 has a length of 4 mm, the core tube body 1 has a diameter of 0.3 mm, the core end portion 2 has a thickness of 0.3 mm, and the core end portion 2 has a diameter of 0.7 mm.
- Patients with dry eye syndrome B recovered 33 days after using the tear tube of this size every day.
- the core tube body 1 has a length of 8 mm, the core tube body 1 has a diameter of 0.5 mm, the core end portion 2 has a thickness of 0.5 mm, and the core end portion 2 has a diameter of 0.9 mm.
- Patients with dry eye syndrome were rehabilitated 32 days after using a small size of this class of tear ducts.
- the core tube body 1 has a length of 10 mm, the core tube body 1 has a diameter of 0.8 mm, the core end portion 2 has a thickness of 0.8 mm, and the core end portion 2 has a diameter of 1.2 mm.
- the patient is rehabilitated for 36 days after using the tear tube of this size every day.
- the patient who is burned by acid and alkali burns the core of the tear tube with this size every day.
- the preventive effect is good and the lacrimal duct is not narrowed. , 96 days of rehabilitation.
- the core tube body 1 has a length of 16 mm, the core tube body 1 has a diameter of 0.9 mm, the core end portion 2 has a thickness of 0.9 mm, and the core end portion 2 has a diameter of 1.3 mm.
- Patients with dry eye syndrome have used this type of tear tube to prevent core, and recovered for 40 days.
- Patients with acid-base burns use the tear tube of this size every day.
- the preventive effect is good and the lacrimal duct is not narrowed. , 98 days of recovery.
- the core tube body 1 has a length of 20 mm, the core tube body 1 has a diameter of 1 mm, the core end portion 2 has a thickness of 1 mm, and the core end portion 2 has a diameter of 1.5 mm.
- Patients with dry eye syndrome use 37-day rehabilitated tears of the small size of the tear tube after daily use.
- Patients with acid-base burns use the tear ducts of this size every day. The preventive effect is good and the lacrimal passage is not narrowed. , 100 days of recovery.
- the length of the core tube is 2-8 mm, it is effective as a treatment for dry eye, and is not suitable for preventing narrowing of the lacrimal passage after acid-base burn.
- the length of the core tube is 8-20 mm, it can be used to treat dry eye and prevent narrowing of the lacrimal passage after acid-base burn.
- the core tube body 1 and the core end 2 of the invention are processed by a medical silica gel material or processed by a polyolefin or a polyester medical polymer material, and the material is non-sticky to the new cells, Maintaining the shape of the lacrimal duct, therefore, the proliferating tissue cells after acid-base burn do not adhere to the lacrimal tube and prevent the narrowing of the lacrimal duct.
- the tear-tube-resistance of the material can adsorb drugs and nutritional factors. Drugs and trophic factors can be applied to the surface of the lacrimal canal, so the effect of treating dry eye is particularly significant.
- Embodiment 1 as shown in FIG. 3, the core tube body 1 is provided with a cavity 5, and the core tube body 1 is provided with a micro hole 4 through the core end 2 to the cavity 5 Injecting drugs or nutrient factors, etc., drugs or nutrient factors are slowly absorbed into the lacrimal passage through the micropores 4 and absorbed by the eyes, which can better treat the symptoms of acid-base burns and dry eye in the eyes.
- the tapered tip 3 has a hollow structure
- the head of the tapered tip 3 is blunt and has an opening
- the core tube body 1 and the core end 2 They all have a hollow structure, and the tear canal is prevented from being inserted into the core.
- the hollow structure of the tear tube is designed to allow excess tears to flow out of the eye through the hollow structure of the tear canal, keeping the tears in the eye moderate and treating dry eyes. The effect of the disease is significant.
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Abstract
Description
技术领域Technical field
本发明涉及医疗器械技术领域,特别是涉及一种用于治疗干眼症及防止酸碱烧伤后的泪道变窄的泪小管阻芯。The invention relates to the technical field of medical instruments, in particular to a lacrimal canal core for treating dry eye and preventing narrowing of lacrimal passage after acid-base burn.
背景技术Background technique
干眼症是指眼泪减少或泪腺功能下降引起眼睛干涩、眼酸、眼痒、怕光、视力减退等症状,它损伤眼角膜,严重时会出现角膜软化穿孔。Dry eye syndrome refers to symptoms such as decreased tears or decreased function of lacrimal glands causing dry eyes, acid eyes, itchy eyes, photophobia, and decreased vision. It damages the cornea and, in severe cases, corneal softening and perforation.
目前治疗干眼症的重要方法是泪小点栓塞术。该方法是通过植入泪道栓塞,来封闭泪液排除管道。该方法能保存泪道自身分泌的自然泪液,并延长泪液在眼表面停留的时间。然而,由于泪道栓长度不足,无论是降解性的或者永久性的泪道栓,均不能较好的治疗干眼症。The current important method for treating dry eye syndrome is puncture embolization. The method is to seal the tear exclusion tube by implanting a lacrimal duct embolization. The method preserves the natural tears secreted by the lacrimal passage itself and prolongs the time the tears stay on the surface of the eye. However, due to insufficient length of the lacrimal plug, neither degradable nor permanent lacrimal plugs can treat dry eye.
另外,酸碱烧伤后形成的泪道变窄,目前没有成熟的治疗和预防手段。In addition, the lacrimal passage formed after acid-base burns is narrowed, and there is no mature treatment and prevention means at present.
发明内容Summary of the invention
基于此,本发明在于克服现有技术的缺陷,提供一种泪小管阻芯,它不仅能方便、安全稳定的治疗干眼症,还能预防酸碱烧伤后泪道变窄。Based on this, the present invention overcomes the defects of the prior art and provides a lacrimal tube obstruction core, which can not only treat dry eye disease conveniently, safely and stably, but also prevent narrowing of the lacrimal passage after acid-base burn.
其技术方案如下:一种泪小管阻芯,包括阻芯管体,所述阻芯管体一端具有锥形尖端,所述阻芯管体另一端具有阻芯头端。The technical solution is as follows: a tear tube small core, comprising a core tube, the core tube has a tapered tip at one end, and the other end of the core tube has a core end.
优选的,所述阻芯头端呈无棱角的扁圆柱状,头端没有棱角,损伤眼组织细胞程度低。Preferably, the head end of the core block has a flat cylindrical shape without an angular shape, and the head end has no angular angle, and the degree of damage to the eye tissue is low.
优选的,所述阻芯管体长为2~20mm,阻芯管体直径为0.1~1mm;阻芯头端厚度为0.1~1mm,阻芯头端直径为0.5~1.5mm,阻芯管体适合于不同病人泪道的治疗,且阻芯管体足够长,探入泪道后,形状可随泪道的弯曲而变形,所以泪小管阻芯与泪道接触牢固,进而不会下滑到泪道,也不易揉眼而掉出,位置长期固定。Preferably, the core tube body has a length of 2-20 mm, the diameter of the core tube body is 0.1 to 1 mm, the thickness of the core end of the resistor core is 0.1 to 1 mm, and the diameter of the head end of the resistor core is 0.5 to 1.5 mm. It is suitable for the treatment of lacrimal passages of different patients, and the core tube is long enough. After entering the lacrimal duct, the shape can be deformed with the curvature of the lacrimal duct. Therefore, the tear tube has a strong contact with the lacrimal duct, and thus does not slip into tears. The road is also not easy to blink and fall out, and the position is fixed for a long time.
优选的,所述阻芯管体长为4~16mm,阻芯管体直径为0.3~0.8mm;阻芯头端厚度为0.3~0.8mm,阻芯头端直径为0.7~1.0mm。Preferably, the core tube has a length of 4 to 16 mm, the diameter of the core tube is 0.3 to 0.8 mm, the thickness of the core end of the core is 0.3 to 0.8 mm, and the diameter of the head end of the core is 0.7 to 1.0 mm.
优选的,所述阻芯管体与所述阻芯头端为医用硅胶材料加工制造或聚烯、聚酯类医用高分子材料加工制造,该种材料与新生细胞不粘黏,能保持泪道形状进,因此,酸碱烧伤后增生的组织细胞不粘附在泪小管阻芯上,预防泪道变窄效果显著,其次,该种材料的泪小管阻芯能吸附药物与营养因子,药物与营养因子能涂在泪小管阻芯表面来给药,因此,用来治疗干眼症的效果也尤为显著。Preferably, the core tube body and the core end of the core are processed by a medical silica gel material or processed by a polyolefin or a polyester medical polymer material, and the material is non-sticky to the nascent cells and can maintain the lacrimal passage. The shape enters, therefore, the proliferating tissue cells after acid-base burn do not adhere to the lacrimal tube and prevent the narrowing of the lacrimal duct. Secondly, the tear-throat block of the material can adsorb drugs and nutritional factors, drugs and Nutritional factors can be applied to the surface of the lacrimal canal, so the effect of treating dry eye is particularly significant.
优选的,所述阻芯管体内设有空腔,在所述阻芯管体上设有微孔,在空腔内放置药物或者营养因子等,通过该微孔能使其缓慢释放后被眼睛吸收,能较好的治疗眼睛酸碱烧伤症状以及干眼症。Preferably, the core tube is provided with a cavity, a micro hole is arranged in the core tube body, and a drug or a nutrient factor is placed in the cavity, and the micro hole can be slowly released and then used by the eye. Absorption, can better treat eye acid and alkali burn symptoms and dry eye syndrome.
优选的,所述锥形尖端呈中空结构,所述锥形尖端的头部圆钝且有开口,所述阻芯管体与所述阻芯头端均呈中空结构,将该种泪小管阻芯植入,泪小管阻芯采取中空结构是为了让多余泪液能经过泪小管阻芯的中空结构流出眼睛外,保持泪道内的泪液适中。 Preferably, the tapered tip has a hollow structure, the head of the tapered tip is blunt and has an opening, and the core tube body and the head end of the resistance core have a hollow structure, and the tear tube is blocked. Core implantation, the hollow tube of the tear duct adopts a hollow structure in order to allow excess tear fluid to flow out of the eye through the hollow structure of the tear duct and prevent the tears in the lacrimal duct from being moderate.
下面对前述技术方案的原理、效果等进行说明:当把该种结构的泪小管阻芯植入泪道后,就能方便、安全稳定的治疗干眼症,还能防止酸碱烧伤后泪道变窄,而且由于具有头端,所以能够方便被镊子取出或植入泪道。The principle, effect and the like of the foregoing technical solutions are described below: when the tear canal of the structure is implanted into the lacrimal duct, the dry eye can be treated conveniently, safely and stably, and the tears after the acid-base burn can be prevented. The channel is narrowed and, because of its head end, it can be easily removed or implanted into the lacrimal passage by the forceps.
附图说明
图1是本发明所述泪小管阻芯的结构示意图;
图2为图1的侧视图;
图3是本发明实施例一所述泪小管阻芯的结构示意图;
图4是本发明实施例二所述泪小管阻芯的结构示意图。BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic structural view of a tear canal core of the present invention;
Figure 2 is a side view of Figure 1;
3 is a schematic structural view of a tear tube small core according to
4 is a schematic structural view of a tear canal core of the second embodiment of the present invention.
附图标记说明:
1、阻芯管体,2、阻芯头端,3、锥形尖端,4、微孔,5、空腔。Description of the reference signs:
1, the core tube body, 2, the core end, 3, tapered tip, 4, micro-hole, 5, cavity.
具体实施方式detailed description
下面对本发明的实施例进行详细说明。The embodiments of the present invention are described in detail below.
如图1和图2所示,一种泪小管阻芯,包括阻芯管体1,所述阻芯管体1一端具有锥形尖端3,所述阻芯管体1另一端具有阻芯头端2。所述阻芯头端2呈无棱角的扁圆柱状,阻芯头端2没有棱角,损伤眼组织细胞程度低。当把该种结构的泪小管阻芯植入泪道后,就能方便、安全稳定的治疗干眼症,还能防止酸碱烧伤后泪道变窄,而且由于具有头端,所以能够方便被镊子取出或植入泪道。由于阻芯管体1足够长,植入泪道后,形状可随泪道的弯曲而变形,所以泪小管阻芯与泪道接触牢固,进而不会下滑到泪道,也不易揉眼而掉出,位置长期固定。下面根据不同人的泪道长短,给出适合治疗不同病人泪小管阻芯尺寸:
所述阻芯管体1长为2mm,阻芯管体1直径为0.1mm;阻芯头端2厚度为0.1mm,阻芯头端2直径为0.5mm。干眼症病人患者甲每天使用该种尺寸的泪小管阻芯后,
28天康复。
所述阻芯管体1长为4mm,阻芯管体1直径为0.3mm;阻芯头端2厚度为0.3mm,阻芯头端2直径为0.7mm。干眼症病人患者乙每天使用该种尺寸的泪小管阻芯后,33天康复。
所述阻芯管体1长为8mm,阻芯管体1直径为0.5mm;阻芯头端2厚度为0.5mm,阻芯头端2直径为0.9mm。干眼症病人患者丙每天使用该种尺寸的泪小管阻芯后,32天康复。
所述阻芯管体1长为10mm,阻芯管体1直径为0.8mm;阻芯头端2厚度为0.8mm,阻芯头端2直径为1.2mm。干眼症病人患者丁每天使用该种尺寸的泪小管阻芯后,
36天康复,被酸碱烧伤的病人戊每天使用该种尺寸的泪小管阻芯后,预防效果好,泪道没有变窄,96天康复。
所述阻芯管体1长为16mm,阻芯管体1直径为0.9mm;阻芯头端2厚度为0.9mm,阻芯头端2直径为1.3mm。干眼症病人患者己每天使用该种尺寸的泪小管阻芯后,
40天康复,被酸碱烧伤的病人庚每天使用该种尺寸的泪小管阻芯后,预防效果好,泪道没有变窄,98天康复。
所述阻芯管体1长为20mm,阻芯管体1直径为1mm;
阻芯头端2厚度为1mm,阻芯头端2直径为1.5mm。干眼症病人患者辛每天使用该种尺寸的泪小管阻芯后,
37天康复,被酸碱烧伤的病人壬每天使用该种尺寸的泪小管阻芯后,预防效果好,泪道没有变窄,100天康复。As shown in FIG. 1 and FIG. 2, a lacrimal canal core comprises a core preventing
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The
The
经过试验、分析可知,当阻芯管体长度在2~8mm时,作为治疗干眼症效果显著,并不适用于预防酸碱烧伤后的泪道变窄。当阻芯管体长度在8~20mm时,均可以作为治疗干眼症及预防酸碱烧伤后的泪道变窄。After testing and analysis, it can be seen that when the length of the core tube is 2-8 mm, it is effective as a treatment for dry eye, and is not suitable for preventing narrowing of the lacrimal passage after acid-base burn. When the length of the core tube is 8-20 mm, it can be used to treat dry eye and prevent narrowing of the lacrimal passage after acid-base burn.
其中,本发明所述阻芯管体1与所述阻芯头端2为医用硅胶材料加工制造或聚烯、聚酯类医用高分子材料加工制造,该种材料与新生细胞不粘黏,能保持泪道形状,因此,酸碱烧伤后增生的组织细胞不粘附在泪小管阻芯上,预防泪道变窄效果显著,其次,该种材料的泪小管阻芯能吸附药物与营养因子,药物与营养因子能涂在泪小管阻芯表面来给药,因此,用来治疗干眼症的效果也尤为显著。Wherein, the
实施例一,如图3所示,所述阻芯管体1内设有空腔5,在所述阻芯管体1上设有微孔4,通过从阻芯头端2向空腔5内注射药物或者营养因子等,药物或者营养因子等通过该微孔4缓慢渗入泪道中被眼睛吸收,能较好的治疗眼睛酸碱烧伤症状以及干眼症。
实施例二,如图4所示,所述锥形尖端3呈中空结构,所述锥形尖端3的头部圆钝且有开口,所述阻芯管体1与所述阻芯头端2均呈中空结构,将该种泪小管阻芯植入,泪小管阻芯采取中空结构是为了让多余泪液能经过泪小管阻芯的中空结构流出眼睛外,保持眼睛内的泪液适中,治疗干眼症效果显著。
以上所述实施例仅表达了本发明的具体实施方式,其描述较为具体和详细,但并不能因此而理解为对本发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。The above-mentioned embodiments are merely illustrative of specific embodiments of the invention, and the description thereof is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention.
Claims (7)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103042139A CN103349588A (en) | 2013-07-15 | 2013-07-15 | Lacrimal ductile blocking core |
| CN201310304213.9 | 2013-07-15 |
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| WO2015006999A1 true WO2015006999A1 (en) | 2015-01-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| PCT/CN2013/080552 Ceased WO2015006999A1 (en) | 2013-07-15 | 2013-07-31 | Lacrimal ductile blocking core |
| PCT/CN2014/080700 Ceased WO2015007139A1 (en) | 2013-07-15 | 2014-06-25 | Canalicular barrier core |
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| Application Number | Title | Priority Date | Filing Date |
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| PCT/CN2014/080700 Ceased WO2015007139A1 (en) | 2013-07-15 | 2014-06-25 | Canalicular barrier core |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106667656A (en) * | 2016-06-30 | 2017-05-17 | 广州聚明生物科技有限公司 | Biodegradable lacrimal passage suppository and preparation method and application thereof |
| WO2022055825A1 (en) * | 2020-09-10 | 2022-03-17 | Oasis Medical, Inc. | Devices and methods for occluding the punctal opening |
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| CN103349588A (en) * | 2013-07-15 | 2013-10-16 | 广州卫视博生物科技有限公司 | Lacrimal ductile blocking core |
| CN104984410A (en) * | 2015-07-29 | 2015-10-21 | 陕西博与再生医学有限公司 | A degradable and controllable lacrimal plug and its preparation method |
| CN106344257B (en) * | 2016-08-31 | 2018-07-10 | 李志强 | A kind of lacrimal passage bolt of body scalable |
| CN106491270B (en) * | 2016-12-23 | 2018-08-14 | 中国医科大学附属第一医院 | A kind of lacrimal point extension fixture |
| CN110711075A (en) * | 2018-07-11 | 2020-01-21 | 吴坚 | Lacrimal duct embolism |
| CN113197722B (en) * | 2021-05-26 | 2025-03-28 | 淮阴工学院 | A lacrimal duct drainage device and a method for preparing the same |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN203915219U (en) | 2014-11-05 |
| CN103349588A (en) | 2013-10-16 |
| WO2015007139A1 (en) | 2015-01-22 |
| CN103876887A (en) | 2014-06-25 |
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