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WO2015006379A3 - Selection of cells for elimination - Google Patents

Selection of cells for elimination Download PDF

Info

Publication number
WO2015006379A3
WO2015006379A3 PCT/US2014/045832 US2014045832W WO2015006379A3 WO 2015006379 A3 WO2015006379 A3 WO 2015006379A3 US 2014045832 W US2014045832 W US 2014045832W WO 2015006379 A3 WO2015006379 A3 WO 2015006379A3
Authority
WO
WIPO (PCT)
Prior art keywords
elimination
cells
selection
surface marker
cell surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2014/045832
Other languages
French (fr)
Other versions
WO2015006379A2 (en
Inventor
Milan N. Stojanovic
Sergei Rudchenko
Maria RUDCHENKO
Steven Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of WO2015006379A2 publication Critical patent/WO2015006379A2/en
Priority to US14/931,941 priority Critical patent/US10338068B2/en
Publication of WO2015006379A3 publication Critical patent/WO2015006379A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Provided herein are molecular automaton system for elimination of a target cell. Some embodiments include modules specific for a target cell having a first cell surface marker and a second cell surface marker. Some embodiments include modules specific for a target cell having a first cell surface marker but not a second cell surface marker.
PCT/US2014/045832 2013-07-08 2014-07-08 Selection of cells for elimination Ceased WO2015006379A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US14/931,941 US10338068B2 (en) 2013-07-08 2015-11-04 Selection of biological objects

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361843892P 2013-07-08 2013-07-08
US61/843,892 2013-07-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US14/931,941 Continuation-In-Part US10338068B2 (en) 2013-07-08 2015-11-04 Selection of biological objects

Publications (2)

Publication Number Publication Date
WO2015006379A2 WO2015006379A2 (en) 2015-01-15
WO2015006379A3 true WO2015006379A3 (en) 2015-11-12

Family

ID=52280710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/045832 Ceased WO2015006379A2 (en) 2013-07-08 2014-07-08 Selection of cells for elimination

Country Status (1)

Country Link
WO (1) WO2015006379A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016154618A1 (en) * 2015-03-26 2016-09-29 IVDiagnostics, Inc. Systems and methods of detecting malignant cells
EP3353326B1 (en) 2015-09-24 2022-08-24 AbVitro LLC Affinity-oligonucleotide conjugates and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012071428A2 (en) * 2010-11-22 2012-05-31 Solulink, Inc. Methods and/or use of oligonucleotide conjugates for assays and detections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012071428A2 (en) * 2010-11-22 2012-05-31 Solulink, Inc. Methods and/or use of oligonucleotide conjugates for assays and detections

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
RUDCHENKO, M ET AL.: "Autonomous Molecular Cascades For Evaluation Of Cell Surfaces.", NATURE NANOTECHNOLOGY, vol. 8, no. 8, 28 July 2013 (2013-07-28), pages 580 - 586, XP055237182, ISSN: 1748-3387 *
SEELIG, G ET AL.: "Enzyme-Free Nucleic Acid Logic Circuits.", SCIENCE, vol. 314, no. 5805, 8 December 2006 (2006-12-08), pages 1585 - 1588, XP055237179, ISSN: 0036-8075 *
STOJANOVIC, MN ET AL.: "Exercises In Molecular Computing.", ACCOUNTS OF CHEMICAL RESEARCH., vol. 47, no. 6, 2014, pages 1845 - 1852, XP055237181, ISSN: 0001-4842 *
ZHANG, DY ET AL.: "Dynamic DNA Nanotechnology Using Strand-Displacement Reactions.", NATURE CHEMISTRY., vol. 3, 24 January 2011 (2011-01-24), pages 103 - 113, XP055237178, ISSN: 1755-4330 *

Also Published As

Publication number Publication date
WO2015006379A2 (en) 2015-01-15

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