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WO2015076780A1 - Barquette de conditionnement rigide à évent destinée à la stérilisation par gaz - Google Patents

Barquette de conditionnement rigide à évent destinée à la stérilisation par gaz Download PDF

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Publication number
WO2015076780A1
WO2015076780A1 PCT/US2013/070722 US2013070722W WO2015076780A1 WO 2015076780 A1 WO2015076780 A1 WO 2015076780A1 US 2013070722 W US2013070722 W US 2013070722W WO 2015076780 A1 WO2015076780 A1 WO 2015076780A1
Authority
WO
WIPO (PCT)
Prior art keywords
tray
cap
wall
rigid
rigid tray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/070722
Other languages
English (en)
Inventor
Tad R. KINYON
Christopher R. JANSEN
Christopher L. OSBORN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bemis Healthcare Packaging Inc
Original Assignee
Perfecseal Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perfecseal Inc filed Critical Perfecseal Inc
Priority to PCT/US2013/070722 priority Critical patent/WO2015076780A1/fr
Publication of WO2015076780A1 publication Critical patent/WO2015076780A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • B65D81/20—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas
    • B65D81/2069—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas in a special atmosphere
    • B65D81/2076—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas in a special atmosphere in an at least partially rigid container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/33—Trays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B2050/005—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers with a lid or cover
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/18—Aseptic storing means
    • A61L2202/182—Rigid packaging means

Definitions

  • the present application relates generally to gas sterilization packaging trays and more specifically to venting and filtration means for such trays.
  • sterilization containers There are many types of sterilization containers which serve various needs.
  • One class of containers are known as hospital sterilization containers and are used to sterilize articles of various shapes and sizes just prior to or within hours or a few days of their intended use. They are usually reusable rigid containers adapted for sterilization typically by steam under pressure e.g. in an autoclave, and are often used with equipment which is re-usable and not disposable.
  • containers are typically loaded and sterilized at the hospital. They are not designed for a particular single product and they are not intended for shipping or to provide long term sterility. They do not typically require heat sealing equipment for closure, but are commonly designed to be mechanically closed by hand. Examples of hospital sterilization containers are One Tray® Sealed Containers from Sterile Containment Technology, LLC of Richmond, California, USA and SteriTite® containers from Case Medical Inc. of Ridgefieid, New Jersey, USA. Hospital sterilization containers are also disclosed e.g. in U.S. Patent Nos.
  • Another class of sterilization containers is known as medical package sterilization coniainers and is designed for sterilization prior to delivery to a hospital or surgical facility.
  • This class of containers is designed for single use and to withstand shipping and distribution.
  • the containers are typically employed by article Attorney Docket No. 20808- WO manufacturers to package disposable or impiantable articles, which are sterilized by the article manufacturer or at a special sterilization service facility usually sterilizing many packages at once which have been loaded into bulk containers.
  • Medicai package sterilization containers typically require heat sealing equipment for closure and often use ethylene oxide gas as the steriiant
  • These medical packaging sterilization containers typically are used to provide many months or years of sterile she!f life for their contents.
  • the present invention relates to medical packaging sterilization containers which may be used by article manufacturers to provide long term sterility of articles which are designed for shipment and storage without the necessity for being used within hours or a day or so of sterilization.
  • Articles, such as medical devices can be held within a medical packaging sterilization container e.g. a sealed tray to protect the contents from microbial contamination, airborne particulates, foreign matter, etc, for an extended period of time e.g. months or years.
  • the medical packaging sterilization container may be a rigid polymeric tray having a peelabSe heat sealed lid stock covering the tray top with contents held inside the tray which may also include package inserts to stabilize the artic!e(s) located therein from movement during transport.
  • disposable medical equipment and implantable devices are sterilized following packaging and before transport to healthcare providers.
  • Common forms of sterilization include irradiation, autoclaving, and treatment with a sterilizing gas, such as ethylene oxide (ETO).
  • certain containers e.g. pouches or trays are provided with a gas permeable membrane, wall or lidding which allows introduction and removal of a sterilizing gas such as ethylene oxide.
  • This gas permeable Sid or wall also functions as a barrier to entry of pathogens such as bacteria, viruses and other microbes.
  • Articles such as medical devices and tools e.g. artificial joints, stents, implantable structures and equipment, surgical knives, catheters, clamps, etc. may be stored and transported in a sterile condition until needed whereupon the contents may be accessed under controlled conditions to minimize infection and Attorney Docket No. 20808- WO introduction of undesirable organisms.
  • These medical packaging steriiization containers often use spunbonded poiyo!efin polymeric sheets such as Tyvek® as a permeable membrane lid or waS! component to permit gas sterilization and to act as a microbial barrier; see e.g. European Patent EP 07850868.
  • Examples of medicai packaging steriiization containers are disclosed in U.S. Patent Nos. 4,022,324 (Schuster);
  • a typical medical device package has a sheet of opaque breathable material sealed to the peripheral: edge of a tray or flexible thermoformed blister container to form a lidding. After placing and sealing an article inside, a sterilizing gas is admitted into the interior of the package through the breathable membrane.
  • thermoplastic coated paper or thermoplastic coated Tyveki thermoplastic coated Tyveki spun bonded polyolefin are opaque and prevent inspection of package contents prior to opening. They are also susceptible to weakened seals and failure in gas steriiization due to the use of elevated temperatures and steam. More careful and time consuming handling must be used to minimize seal failures which negatively impacts packaging productivity and limits the speed at which such packages can be
  • Opening of the package for use also raises potential problems.
  • Use of nonwoven sheet material made of individual fibers that are thermally bonded to each other may potentially result in exposure to, or formation during an opening process, of small fibers that may be deposited on the sterilized article; this a particular concern where such nonwoven spunbonded polyolefin sheets are included as a wali component and form a peelable seam.
  • spunbonded nonwovens such as Tyvek® are expensive.
  • a gas sterilization rigid vented tray having: (a) a synthetic polymer tray wall having an exterior surface and an interior surface and comprising a base and upstanding base sidewali, with a foraminous wall portion in at least one of the base and sidewali; (b) filter media; (c) a foraminous cap; and (d) attachment means for the foraminous cap and tray wail whereby filter media is held by the cap to the foraminous wail portion.
  • the attachment means may include snap fit mechanica! attachment, adhesives, heat seals, fusion seals, ultrasonic welding, or combinations thereof. Also, it is preferred that the filter media be held between the cap and wall.
  • This tray may be provided with a lid attached to the sidewali e.g. at a flange by a continuous seal such as an adhesive seal or a heat seal.
  • the seal is a tamper evident heat seal.
  • the lid is preferably transparent and advantageously may provide an unobstructed view of the tray contents.
  • articles may be packaged within the tray including medical devices, pharmaceuticals, persona! care items or foodstuffs a!l of which may advantageously be sterilized to prevent spoiiage of the contents or illness from contact or ingestion of deleterious microbes, bacteria, viruses, molds, etc. It will be appreciated that the function of the tray and all of its Attorney Docket No. 20808- WO constituent elements, i.e.
  • the tray wails including bottom any sidewaii and the lid which may be considered after package formation as a top wali is to protect the contents of the package from contamination after the article is placed within the tray and the tray is enclosed by sealing with a lid.
  • the sealed tray including lid acts as a physical barrier to entrance of foreign matter e.g. microbes, yeast, molds, bacteria, dirt, airborne particulates, etc. from the environment exterior to the package into the package interior thereby protecting the article held therein.
  • the tray and lid are therefore made of continuous structural materials which act as a physical barrier between the exterior of the package and the interior package.
  • the foraminous wall portion has a continuous and surrounding projecting wall proximate to and enclosing the one or more openings (A) in a first section within an interior space defined by this projecting wall and has no openings within a second section which is also within the interior space defined b the projecting wall; and the cap has a panel and a continuous sidewaii depending therefrom and has one or more openings (B) through the panel in a first section within an interior space defined by the continuous sidewaii and has no openings within a second section which is also within the interior space defined by the continuous
  • the cap is secured to the wall portion with the first and second cap sections oriented with respect to the first and second wall portion sections such that a path from openings A to openings B in its shortest distance DR is greater than a path in its shortest distance DT from an interior surface of the cap panel to an interior surface of the wall portion circumscribed by the projecting wall.
  • the cap is formed e.g. by molding from filter media such as a porous sintered polymer and the filter media and foraminous cap are one and the same with the foramina being the small openings providing tortuous gas Attorney Docket No. 20808- WO passageways from the exterior of the cap therethrough to the interior compartment of an attached tray through one or more openings in the sidewali,
  • FIG. 1 is a perspective view of a vented gas sterilization rigid tray in accordance with the present invention.
  • Figure 2 is a perspective view of an alternative embodiment vented gas sterilization rigid tray with a sidewali located vent in accordance with the present invention.
  • Figure 3 is a plan view of the top of the tray depicted in Fig. 1 .
  • FIG. 1 is a plan view of the bottom of the tray depicted In Fig. 1.
  • Figure 5 is a sectional view of the tray depicted in Fig. 3 taken along !ines 5-5.
  • Figure 8 is an enlarged view of a portion of the tray vent area of Fig. 5.
  • Figure 7 Is a sectional view of a foraminous cap and tray wali portion taken along lines 7-7 of Fig. 6.
  • Figure 8 Is an exploded view of the foraminous cap, filter media, and tray wall portion depicted in Fig. 7.
  • Figure 9 Is a sectional view of an alternative embodiment of the foraminous cap, filter media, and tray wall portion depicted in Fig. 7.
  • Figure 10 Is a schematic top view of an alternative foraminous cap and tray wali portion in accordance with the present invention.
  • Figure 1 1 is a sectional view taken along lines 11 -11 of Fig. 10. Attorney Docket No. 20808- WO
  • Figure 12 is an enlarged view of the cap, filter media, and tray portion depicted in Fig. 11 showing gas movement directions.
  • Figure 13 is an exploded perspective view of an alternative embodiment of the invention.
  • the present invention relates to package sterilization containers which may be useful for sterilizing a variety of articles from food to medicai supplies.
  • the inventive package is disposable, designed for single use applications.
  • the invention may be beneficially employed as a disposable, intended for single use, medicai package sterilization container.
  • Articles may be sealed within a tray according to the present invention to provide a physical barrier between the sealed tray interior and exteriorly located contaminants such as microbes and particulates in the
  • the sealed package may then undergo gas sterilization processes to decontaminate the interior contents of the sea! tray.
  • Porous materials such as medical grade paper and Tyvek® spunbonded polyolefin sheets are often used for prior art gas sterilization packaging.
  • the gas permeability of these materials is such that it allows for flow of steriiant and flushing gases into and out of the package being sterilized.
  • These materials maintain the sterility of the package as they prevent bacteria and other microbes from entering the package.
  • Tyvek® is very expensive and paper does not typically have as good of a microbial barrier as Tyvek®. Both of these materials are opaque and obscure viewing of package contents when used, as is typical, as the fray lid o as a portion thereof.
  • porous medical device packaging systems the porous material allows for proper gas flow, but can also be thought of as a filter medium in order to provide microbial barrier.
  • Impaction play a strong role in filtration.
  • low gas flow situations such as storage, Diffusion, Gravitational Effects, and ESectrokinetic Effects play a prominent role in filtration.
  • Tyvek® and paper depend upon all of these methods to create a sufficient microbial barrier.
  • the tortuous path inherent in the structure of Tyvek® as well as its electrostatic properties make Tyvek® an excellent microbial barrier for packaging medical devices.
  • a novel vent design utilizes an increased gas flow rate coupled with a thicker filter media or longer filtration path e.g. created by a change in flow direction with a predominant transverse or cross-directional flow through a vent which permits use of other filter media. This resuits in an adequate or improved microbial barrier through one or more of the following mechanisms:
  • the surface area at the opening or openings on one side of the vent may be selected to be greater than the surface area of opening(s) on the other side of the filter media and vent, and optionally offset therefrom, the flow rate of individual particles may change as gas traverses the material in its multiple directions (i.e. transverse or cross-directional to the sheet thickness), allowing for more diffusion impactions as the particle velocity changes in transit.
  • both the cap and a portion of the tray wall are "foraminous" meaning that the cap and wall portion each has one or more openings (these openings may also be termed apertures or holes). These openings may be formed by a variety of means and in a variety of shapes and sizes. As a general rule the holes should be small enough to retain the filter media and, if needed, avoid any unwanted contact between the media and a packages contents, yet large enough to facilitate gas flow rates, while maintaining integrity of the tray wail and cap.
  • the opening size and its passageway dimensions and the number of openings are parameters which may be controlled to provide the desired gas flow rate.
  • Other considerations in design of hole size, number and shape include: volume of the tray to be sterilized, gas exchange rates, filtration resistance, spatial relationships between any Attorney Docket No. 20808- WO two or more notes.
  • Suitable holes for various vents may be made by use of lasers e.g. a CO2 laser, hot needles, mechanical drilling, or punching.
  • a vent may be provided by construction of a wall portion or cap made from a porous material such as porous sintered polymers e.g. a porous sintered poiyoiefin, preferably porous sintered polyethylene or PCTFE.
  • the sintered cap or wall portion comprises the filter medium in addition to functioning as a cap and/or wall.
  • Each method of hole creation has its own advantages and drawbacks e.g. use of punches is inexpensive and produces few fibers but chads may be created and the variable depth of trays may make set up and operation diff icult or add expense; use of drills may be precise but are expensive and produce undesirable fines and fiber debris; hot needles may be quick and useful particularly for thin gauge materials, but may cause heat distortion of the cap or wall for larger thicknesses; lasers have an expensive fixed cost and have safety considerations, require smoke & gas removal, but do not produce fibrous debris or fines and create openings having a nice glassy edge e.g.
  • a relatively small opening (or small opening area provided by a plurality of openings) in a rigid tray wall provides fluidic communication between the exterior of the package container and its interior so that gases may enter or exit the opening with passage through a filter which may be placed on either side of the opening.
  • the filter provides a tortuous gas passageway from the tray exterior opening through the filter until reaching the interior compartment of the tray.
  • the filter retaining cap has an opening to complete the fluidic communication with the tray interior.
  • This cap opening ma also be relatively small (or have a small opening area provided by a plurality of openings).
  • the filter and cap may be placed on the tray exterior so that gases enter and exit from the iray exterior through the cap then the filter and through the opening in the wail portion of the tray.
  • the cap may be on either the tray interior or exterior with the filter media held between the cap and tray Attorney Docket No. 20808- WO wall in another embodiment, a wall portion or cap is formed from filter media itself rather than being a separate component.
  • an opening area and a wall may be provided with a porous sintered polymer cap which itself provides both desired filtration of microbes and desired gas flow rates.
  • more permeable materials can be used as the porous medium.
  • more permeable structures are open cell foams, sintered porous plastics, high loft nonwoven fabrics, and woven fabrics. Since these materials are more permeable, less surface area of material is required over or as part of a package wall. Since Tyvek® is typically the most expensive material in a packaging system, these alternate materials may be less expensive than Tyvek®, and a reduction in porous surface area required should a!low for a reduction in overall cost while providing the possibility of other benefits including Improved visibility of package contents.
  • the venting means may be relocated from the lid to the tray thereby allowing use of a highly clear, transparent lid providing an unobstructed view of the contents of the tray.
  • the lid may be made of a nonporous or nonpermeable material and/or may also be formed of an oxygen and/or moisture barrier material.
  • the lid may be made of a nonpermeable material which also functions as a retainer to prevent undesired movement of an enclosed article, e.g. during shipping and handling, by combining the functions of Sid and a retainer in a single component.
  • a novel gas sterilization package tray which suitably comprises a vented rigid tray for gas sterilization having: Attorney Docket No. 20808- WO
  • a synthetic polymer tra wail having an exterior surface and an interior surface and comprising a base and upstanding base sidewait with a foraminous wall portion in at Seast one of the base and the sidewaii;
  • attachment means for the foraminous cap and the tray wal! whereby the filter media is held between the cap and the foraminous wal! portion and the attachment means are provided by snap fit or press fit mechanical fastening, adhesive, heat sealing, ultrasonic welding, or combinations thereof.
  • the present invention provides packages which have both microbial filtration and gas venting (i.e. communication back and forth between the package interior and exterior).
  • the tray walls and Sid are formed of materials to provide a barrier to transmission of microbes, particulates, dirt, foreign matter, etc. between the exterior and interior of the package. The same materials typica!!y render the walls and lid
  • the inventive package and tray equips the tray with a powerful yet small vent that has filtration capability.
  • this vent has (a) a first apertured wall !ayer having an opening of area "A”, (b) a second apertured cap layer having an opening of area ,S B". and (c) filtration media disposed between and in contact with layers (a) and (b).
  • the first apertured wall layer has an opening of area "A" in a first section and has a second section having a nonapertured area greater than "A" and located in an area distinct from the apertured area.
  • the second apertured cap layer is similarly defined with a first apertured section having an opening of area "B” and a second nonapertured section and the cap and wall layers are fixed relative to one another such that the apertured first section of the wal! layer overlays the second nonapertured section of the cap layer.
  • the nonapertured second section of the wall !ayer overlays the first apertured section of the cap layer.
  • the materials selected for the wall layer and cap are typically sufficiently restrictive to air flow through their thicknesses that gas flow is diverted or directed to the openings in wall and cap and from these openings
  • the predominate gas flow into and out of the novel vent is caused to turn 90° which permits a gas transit distance greater than the thickness of the filter media sheet, and preferably at least twice this distance.
  • Suitable materials which may be selected and used for layers of the tray wail and cap include many of the same materials thai may be used to construct a typical tray wall and may be monolayer or multilayer in construction. Lid stock for the lid used with the tray may also use similar materials. Examples of such materials include polyolefins, polyethylene terephtha Sates, polyamides, nylons, polystyrenes, polyacrylates, cyclic polyolefins, generally any polymer that is known for use in polymeric packaging. Such materials may be homopoiymers, copolymers, and their derivatives and blends thereof. Metal foils and meta!ized films are also contemplated.
  • One or more functional properties may be contributed by one or more layers including desired levels of heat seaiability, optical properties e.g. transparency, gloss, haze, abrasion resistance, coefficient of friction, tensile strength, flex crack resistance, puncture resistance, abrasion resistance, portability, coiorfastness, flexibility, stretch or shrinkability, dimensional stability, barrier properties to gases such as oxygen, or to moisture, light of broad or narrow spectrum: including e.g. uv resistance, etc.
  • Preferred materials for use as container walls, and Sidstock include nylons, polyesters, polystyrenic polymers, and polyolefin e.g.
  • polystyrene resin ethylene or propylene homopoiymers or copolymers, or mixtures thereof in any number of layers, particularly, but not limited to, one to nine or 1 layers or more.
  • Preferred polyolefins include ethylene homopoiymers or copolymers and may include low, medium, high and ultra-low or ultra-high density polymers. Examples are high Attorney Docket No. 20808- WO density polyethylene (HOPE), ethylene aipha-oiefin copoiymers (EAO) preferably utilizing butene-1 , hexene-1 , or octene-1 comonomer with a predominate ethylene comonomer portion) and including e.g.
  • HOPE high Attorney Docket No. 20808- WO density polyethylene
  • EAO ethylene aipha-oiefin copoiymers preferably utilizing butene-1 , hexene-1 , or oc
  • LLDPE linear low density polyethylene
  • VLDPE very low density polyethylene
  • plastomers elastomers
  • LDPE low density polyethylene copoiymers of ethylene and polar groups such as vinyl acetate or ethyl acryiate e.g. ethylene vinyl acetate (EVA) or ethylene methyl acryiate (EMA) or ethylene acrylic acid copo!ymer(EAA) t functional group modified polymers including e.g. anhydride modified EAOs.
  • Propylene homopolymers and copolymers including polypropylene and propylene ethylene copolymer are useful, in some embodiments of the invention tray and !id layers in may utilize a gas barrier layer such as aluminum foil, poiyvinylidene chloride copolymers such as saran, polyacrylonitriles, or ethylene vinyi alcohol copolymers which provide high barriers to gas permeability or materials such as nylon which impede gas permeation to a lesser extent, or materials such as polyethylene which are generally not considered oxygen barriers.
  • Gas barrier embodiments may be used for sterilization followed by purging the package interior with an inert gas and sealing or capping the vent to provide a hermetic package. This may be useful to package articles sensitive to the presence of oxygen over time.
  • Tray including tray wall and cap, and Sid layers in accordance with the present invention may utilize a sealant layer which can include polyethylene, ionomer, polyacryionitrile, polyester, Barex®, or Surlyn®, Lid or trays may be multilayer coextrusions or laminates which may include more layers than those described above such as one or more adhesive layers to bond together layers which might otherwise have weak bonds and be subject to delamination or for other property enhancements or reasons of performance or cost.
  • a sealant layer which can include polyethylene, ionomer, polyacryionitrile, polyester, Barex®, or Surlyn®
  • Lid or trays may be multilayer coextrusions or laminates which may include more layers than those described above such as one or more adhesive layers to bond together layers which might otherwise have weak bonds and be subject to delamination or for other property enhancements or reasons of performance or cost.
  • the synthetic polymer tray wall comprises a polyo!ef in, polyester, polyurethane, polystyrene, cyclic olefin copolymer, or combinations thereof.
  • the synthetic polymer tray wall comprises a polyester terephthalate (PET) hornopo!ymer or copolymer, amorphous PET (aPET), glycol Attorney Docket No. 20808- WO modified PET (PETg), high impact polystyrene (HIPS), high density polyethylene (HDPE), polypropylene or combinations thereof.
  • packaging articles which have rough surfaces such as implants
  • One type of polymeric surface layer with advantageous abrasion resistance is based upon thermoplastic aromatic polyether polyurethane. DeerfieJd Urethanes, a subsidiary of Bayer, markets suitable
  • thermoplastic aromatic polyether polyurethane films under the trademark Durefiex ⁇ with grade PT9400 being particularl suitable, it is also advantageous to use this
  • the synthetic polymer tra wall comprises a multilayer structure having at least one layer of polyester terephthalate (PET) homopolymer or copolymer, and an interior surface layer comprising
  • trays out of materials which can be readily thermoformed into packages of suitable rigidity The typical packaging material for medical implants including femoral stem components has been sheets or films of polyethylene terephthalate glycol (PETG) because they have adequate rigidity and mechanical strength and good thermal formability. However, it is sometimes desirabie to have greater abrasion resistance than this material offers. This material may be used with a laye of thermoplastic aromatic polyether polyurethane in a multilayer
  • This laminate is conveniently formed by melt laminating the polyurethane to the PETG.
  • a preferred PETG for this lamination is Eastman's Eastar 8763 PETG resin.
  • the thicknesses for both fiims should be compatible with both thermoforming the package configuration and providing adequate mechanical strength.
  • a convenient range for the polyurethane is between about 0.01 and 0.025 inches while for the PETG it is between about 0.015 and 0.04 inches.
  • the synthetic poiymer tray wall comprises a multilayer structure having an interior surface layer comprising poSyurethane or a cyclic olefin copolymer.
  • Adhesives useful in the present invention include permanent adhesives and pressure sensitive adhesives commonly available from many commercial sources. It is contemplated that acrylic and anhydride modified polymers may be employed as well as many adhesives which may be selected depending upon other material selections for the filter material as well as the gas diversion layer materials.
  • Additives and processing aides may also be incorporated into the tray wall, cap and/or filter media of the present invention.
  • the thickness of the multilayer structure laminate may be any suitable thickness that provides structural integrity, and desired combinations of properties which may vary depending upon the nature of the contents 1 usage requirements and which may include e.g. consideration of rigidity, structural support, tensile strength,
  • the synthetic polymer tray wall has a typical average thickness between about 20 mil to 60 mil (508-1524 microns), and preferred thickness of 30 to 50 mil (762-1270 microns); more preferably about 40 mil (1016 microns).
  • the lid has a typical thickness between about 2 to 20 mil (51 -508 microns ( ⁇ ) note and preferred thickness of 2-10 mil (51-251 microns); more preferably 3-6 mil (76-152 ⁇ ).
  • the cap has a typical thickness between about 15-60 mil (381 -1524 ⁇ ), and preferred thickness of 20-50 mil (508-1270 microns; more preferably 30-40 mil (762-1016 ⁇ ).
  • the cap may be a snap-on rigid cap or a semi-rigid cap or even a sheet or film cap which is fastened to the tray wail by adhesive or fusion e.g. by heat sealing or ultra-sonic welding or fastened by a combination of means, for example, by mechanica! means such as a snap-on cap coupled with an adhesive which sets over time,
  • a filtration media is used to provide gas transport between opposing exterior and interior sides of a package wall while inhibiting, reducing or preventing passage of smali particles, foreign materials, viruses, and microbes.
  • Suitable filtration media may be fibers, disks or sheets and may be polymeric, cellulosic or non-celSuSosic or a combination thereof.
  • Suitable oeSlulosic materials include cotton including air laid, carded, fibrous cotton wadding, wood pulp such as fluff pulp and non-wood plant counterparts.
  • Suitable non-ce!luiosic materials include
  • thermoplastics that can be used to provide porous thermoplastic filter media sheets which inciude but are not limited to, homopolymers and copolymers of poiyoiefins, polyurethanes, polyamides, nylons, polycarbonates, poly (ether sulfones),
  • f!uoropolymers such as po!yietrafluoroethyiene (PTFE) and polyvinylidene fluoride
  • PVDF polyvinylene
  • a preferred thermoplastic is a poiyoiefin.
  • suitable poiyoiefins inciude but are not limited to: ethylene vinyl acetate; ethylene methyl aery late; polyethyienes; poly propylenes including nonwoven spunbonded
  • polypropylene ethylene-propylene rubbers; ethylene-propylenediene rubbers; po!y(1- butene); polystyrene; poly(2 ⁇ butene); poly(1 ⁇ pentene); poiy ⁇ 2 ⁇ pentene); po!y(3-methyl ⁇ 1 - pentene); poly(4 ⁇ methyi ⁇ 1-pentene); 1 ,2-poiy ⁇ 1 ,3-butadtene; l4 ⁇ poSy ⁇ 1 ,3-butadiene; polyisoprene; poSychloroprene: poiy(vinyi acetate) ; poly(viny!idene chloride); and mixtures and derivatives thereof.
  • a preferred poiyoiefin is polyethylene homopoiymer or copolymer.
  • suitable polyethyienes include, but are not limited to, low- density polyethylene, high density polyethylene, ultra-high molecular weight Attorney Docket No. 20808- WO polyethylene, ethylene aSpha-oSefin copoiymers such as linear low density polyethyiene or very low density polyethylene, and derivatives thereof.
  • Suitable filter media sheets made of porous sintered thermoplastics such as polyolefins may be made from the materials and by the processes as more fully described in U.S. Patent No. 6,551 ,608, U.S. Publication No.
  • filter media may include e.g. air iaid. wet laid or dry laid nonwovens of materials such as polypropylene, polyethylene, polyester, nylon, celluiose or combinations thereof.
  • Electrostatic air filtration materials such as TechnostatTM from Holiingsworth & Vose may be adapted for use e.g. air laid
  • polypropylene fiber mats which are needle punch bonded to a polypropylene
  • the filter media may also be made from open DCled foamed polymers. It has long been known that a "foam" of poiyurethane can be prepared by reacting a "foam" of poiyurethane.
  • polyisocyanate with a poly-hydroxy compound in the presence of a small amount of water which acts as a blowing agent.
  • the water reacts with isocyanate groups producing carbon dioxide gas which forms small gas bubbles or ceils in the "foam" when the poiyurethane sets.
  • Such "foam” products have a structure made up of numerous individual ceils which generally are constructed of a three dimensional skeletal structure of
  • thermoplastic materials of the invention may further comprise materials such as lubricants, colorants, fillers, processing additives, and mixtures thereof.
  • Suitable fillers include, but are not limited to: mtcrocrystalline cellulose, DCF, calcium carbonate, calcium siliceous fillers, polyethyiene fibers and filaments, and mixtures thereof.
  • antimicrobial, anti-bacterial, anti-viral and anti-mycotic agents may be incorporated within the filter medium structure.
  • Suitabie agents include e.g., natural antimicrobial agents; polymeric antimicrobial agents; phenolic and chlorinated phenolic compounds; resorcinol and its derivatives; bisphenolic compounds; benzoic esters; halogenated carbaniiides; thazoiines; trichioromethylthiol ides; metal salts; silver ions; and mixtures thereof as further described in U.S. Patent No. 6,551 ,608, It is desirable that the filter media be contained to prevent direct contact with the tray contents e.g. a medical device to avoid contact transfer of any media material or additives via the device to a patient.
  • this filtration media is a microporous structure which may be e.g. a sintered thermoplastic e.g. sintered porous poSyo!efin e.g. an ultra-high molecular weight polyethylene, or an open celled polymeric material such as those sold under the trademark Porex® by Porex Technologies GmbH of Aachen, Germany.
  • Preferred materials are chemically Inert, and have excellent physical properties including high tensile strength and temperature resistance to withstand elevated temperatures and steam employed in gas sterilization processes.
  • Other desirable properties for preferred embodiments of the invention include filter media having oleophobic and hydrophobic properties and uniformity of pore size.
  • porous PTFE material which is an expanded po!ytetrafluoroethylene (PTFE) polymeric film is commercially available under the Porex trademark.
  • Expanded polytetrafluoroethylene (PTFE) films are further described in U.S. Patent Nos. 3,953,568; 4,187,390; 4,945,125; 5,066,683; 5,157,058; and 5,362,553 each of which is hereby incorporated by reference in their entireties. Expanded PTFE materials are also available commercially from Tetratec, Philadelphia, Pa. as Tetratec #1305 and from Sumitomo Electric Industries, Osaka, Japan under the Attorney Docket No. 20808- WO brand Poreflon® WP-100.
  • An expanded PTFE fiSm typically comprises a plurality of nodes interconnected by fibrils to form a microporous structure.
  • Sintered porous polymers may be used to form a cap and/or wail portion in accordance with the present invention thereby combining the filter media and the cap and/or wall into a single component.
  • Porous filter media according to the present invention have a preferred average pore size between about 1 to 500 microns.
  • the pore size will preferably have substantial uniformity, although materials with a range of pore sizes are suitable.
  • Filter media such as sintered polymers from Porex are compatible with steam and ethylene oxide sterilization processes and may be ultrasonicaily welded or heat sealed.
  • Gurley Hill porosity values may be used to select the materials.
  • Gurley Hill porosity refers to the air resistance of an approximately 8.45 cm 2 (1 in 2 ) circular area of test sample using a pressure differential of 1.22 kPa and Is measured in accordance with International Standard ISO 5636-6, "Paper and board— Determination of air permeance and air resistance (medium range)— Part 5: Gurley method.”
  • Gurley Hill porosity values are reported in the amount of time (seconds) required for a given volume (100 cm 3 ) of air to pass through the test sample, in general, Gurley Hiil porosity values indicate the gas barrier strength of a sample; lower values indicate the sample is more porous. Samples with Gurley Hill porosity values greater than 300 seconds are generally considered substantially non-breathable.
  • the filter media has a typical thickness between about 25 to 250 mil (635 - 6350 ⁇ ) ; and preferred thickness of 60 to 125 mil (1524-3175 microns).
  • FIG. 1 depicts a perspective view of a vented, rigid tray 10 in accordance with the present invention.
  • Tray 10 has a tray wall 11 , preferably made from synthetic polymer, and having an exterior surface 12 and Attorney Docket No. 20808- WO interior surface 13.
  • the tray wall 1 1 comprises a base 14 and upstanding base sidewall 15.
  • the sidewai! 15 may have a sidewall flange 16 which is adapted to receive a heat sealabie or adherabie !idstock on an upper flange surface 17.
  • the sidewall 15 may also be equipped with an interna! rim 18 for receiving an article-stabilizing insert (not shown).
  • the tray 10 is also equipped with a vent 19 in its base 14.
  • the vent 19 has a
  • the base 14 and base sidewall 15 are preferably integrally formed of a single polymeric sheet e.g. by thermoforming and the base 14 and base sidewall 15 portions of the tray wall 1 1 meet at base perimeter 22.
  • tray 1 10 depicts a perspective view of a vented, rigid tray 1 10 in accordance with the present invention.
  • Tray 110 is similar to the tray 10 of Fig. 1 except for the vent location.
  • tray 1 10 has a tray wall 11 preferably made from synthetic polymer, and having an exterior surface 1 12 and interior surface 113.
  • the tray wall 11 1 comprises a base 1 14 and upstanding base sidewall 1 5.
  • the sidewall 115 may have a sidewai! flange 116 which is adapted to receive a heat sealabie or adherabie Sidstock on an upper flange surface 1 17.
  • the sidewall 1 15 may also be equipped with an internal rim 1 18 for receiving an article-stabilizing insert (not shown).
  • the tray 1 10 is also equipped with a vent 1 19, however in this embodiment the vent 1 9 is located in its sidewai! 1 15,
  • the vent 1 19 has a foraminous cap 120 having a plurality of holes 121.
  • the base 114 and base sidewai! 1 15 are preferably integrally formed of a single polymeric sheet e.g. by thermoforming and the base 114 and base sidewai! 1 15 portions of the tray wall 1 1 1 meet at base perimeter 122.
  • FIG. 3 a top plan view of the tray 10 of Fig. 1 is shown.
  • rigid tray 10 having tray wall 1 1 clearly shows the vent 19 having a foraminous cap 20 with holes 21
  • the vent 19 is centrally located in the base 14 within the base perimeter 22.
  • Tray 10 has a tray wall 1 1 and interior surface Attorney Docket No. 20808- WO
  • Tray wall 1 1 has a sidewali flange 16 with an upper flange surface 17 for receiving an attachable, preferably clear and transparent, lid.
  • Upper flange 17 is
  • a lid may be attached to the tray 10 by several means.
  • the lid may be a plastic snap- on iid where the Sid has an outer rim which expands and snaps around flange 16.
  • the Sid will be a heat scalable, thermoplastic film which may be heat sealed to the upper flange surface 17 thereb providing a continuous seal around an interior compartment 24 of the tray 10.
  • the lid may be sealed entirely around a perimeter 25 which defines a tray opening into its internal compartment 24, while the while seal does not extend into an flange area extension 26 having pulitab grooves 23, These grooves 23 and proxtmate extension area 26 is an area of the flange 17 which is not heat sealed and therefore a user may grasp a lid edge and manually, peelably remove the lidding film from the upper flange surface 1 .
  • the lidding film used in various embodiments of the invention may be chosen to be heat sealabte to compatible material on the upper flange surface 17 to provide a strong heat seal which is also manually peelable and may , in addition, provide evidence of a continuous seal, or Sack thereof, through a tamper evident feature in which, upon removal of the lid film by peeling, the Sid is transformed from transparency to a mi!ky white opaqueness. This is a visual indicator which may be used to check whether the iid has been properly sealed and whether it is properly sealed just prior to opening. Prior to removal the Sid is continuously heat sealed about the perimeter 25 of the upper flange surface 17 thereby enclosing the interior compartment 24.
  • the lid attached to the upper flange surface Prior to peeling the lid attached to the upper flange surface should be transparent in appearance. Upon detachment from the flange surface 17 the lid should become opaque and have a milky white appearance: if it does not then it may not have been properly sealed wherever there is a discontinuity in the opaqueness.
  • a transparent clear lidding heat sealed to the upper flange surface 17 also advantageously provides a tray having an unobstructed view of its interior.
  • the Attorney Docket No. 20808- WO interior compartment 24 of tra 10 may also utilize a transparent insert which is seated on rim 18 to stabilize an article held therein and this insert may likewise be of
  • this article will be a medical device such as an implantable prosthetic device such as a hip joint, knee joint, or other medical devices e.g. a catheter, scalpel, etc.
  • the vent 19 is constructed so that sterilant and purge gases may communicate through plurality of holes 21 between the interior compartment 24 and the environment exterior to the tray 10 while at the same time the vent filters out unwanted, deleterious materials and agents such as harmful bacteria, molds, viruses, dust, etc.
  • a bottom plan view of the tray 10 of Figs. 1 and 3 is shown, in this view, rigid tray 10 having tray wall 11 clearly shows the vent 19 having a foraminous wall portion 27 with holes 28.
  • the vent 19 is centrally located in the base 14 within the base perimeter 22.
  • Tray 10 has a tray wali 1 1 and exterior surface 12 of the tray wall 11 equipped with a rim 18, Tray wali 1 1 has a sidewa!l flange 16 with an lower flange surface 29 connected to rim 18 which in turn is connected by tapering side wall section 30 to base perimeter 22.
  • Flange 16 is provided with a flange extension area 26 in one corner with pull tab grooves 23 which on its reverse side assists in lid removal.
  • a lid may be attached to the tray 10 by several means.
  • the lid may be a plastic snap-on lid where the lid has an outer rim which expands and snaps around flange 16 removably hooking on the tower fiange surface 29,
  • the vent 19 is constructed so that sterilant and purge gases may communicate through plurality of holes 28 which extend from the exterior surface 12 of the tray wall base 14 to th interior surface (See Fig. 3) so that these gases pass through a filter media (See Figs. 6-8) between the interior compartment (See Fig. 3) and the environment exterior to the tray 10 via foraminous cap holes 21 (See Fig.
  • the exterior surface 31 of the base 14 is circumscribed by base perimeter 22 and Attorney Docket No. 20808- WO may be provided with a plurality of raised extensions or feet 32. These feet may be integraily formed e.g. by therm of orming. The feet 32 provide a separation between the tray vent 19 and any flat surface upon which the tray rests e.g. a surgical table or sterilizing tray.
  • FIG. 5 a sectional view of the tray 10 depicted in Fig. 3 taken along lines 5-5 is shown.
  • the rigid tray 10 has a tray wall 1 1 which comprises a base 1 and upstanding base sidewal! 15 forming an interior compartment 24.
  • the vent 19 is clearly shown with its foraminous cap 20 having holes 21 connected to the sidewal!
  • Tray 10 has a tray wall 11 with an exterior surface 12 and opposing interior surface 13. This interior surface 3 of the tray wail 1 1 has a peripheral rim 18 formed therein.
  • Tray wall 11 has a sidewal! flange 16 with an upper flange surface 17 and lower flange surface 29 connected to rim 18 which in turn is connected by tapering side wall section 30 to base perimeter 22.
  • Flange 16 is provided with a flange extension area 26 in one corner with pu!l tab grooves 23 which assist in lid removal.
  • Vent 19 may be recessed slightly, as shown, to prevent contact of the fray or table surface with the area adjacent to the vent 19 and this recess may also facilitate gas flow into and out of the vent holes 28. This may be useful e.g. where the tray is subjected to conditions where steam condensation may occur since a recessed location e.g. on the tray base may assist in protecting the vent from condensate.
  • projecting from an exterior surface 31 of the base 14 are a plurality of feet 32 which elevate the exterior base surface 31 to space apart the vent 19 from a surface such as a flat tray or table. This spacing further facilitates prevention of contact of the area adjacent the vent 19 with a tray or table surface and any contaminates or liquids which may be present thereon and further may facilitate the aforementioned gas transfer.
  • Vent 19 comprises a foraminous cap 20 having holes 21 and a mating foraminous wa!i portion 27 which has holes 28 which are preferabiy axially offset from alignment with holes 21.
  • Filter media 33 held between cap 20 and wall portion 27 are filter media 33.
  • Attachment means are provided to connect together the foraminous 20 and the tray wail 11 and the foraminous wall portion 27 These attachment means are preferabiy snap fit attachment means whereby filter media 33 is held between the cap 20 in the foraminous wall portion 27.
  • the foraminous wail portion 27 has a continuous projeciing wail 34 proximate to and surrounding the foraminous wall portion 27 which by definition contains at least one hole, and in this depicted embodiment a plurality of holes 28.
  • the projecting wali 34 extends from the tray wall 11 towards the interior compartment 24 of the tray 10 (See Fig, 5),
  • the projecting wall of the vent may extend from the tray wall 11 towards the exterior of the tray in which case the filter media and cap placement are made on the exterior surface of the tray.
  • the projecting wail 34 may be provided with the least one recess 35 as the projecting wail 34 extends away from base 14.
  • this recess may be a continuous recess about the periphery of a continuous projecting wall 34. While a circular projecting wall is depicted, it is contemplated that projecting walls of various shapes may be employed. For example, it may be desirable to utilize a symmetrical shape or asymmetrical shape, either having a configuration which allows cap placement along any dimension of rotation about an axis perpendicular to the base, or alternatively which requires a specific location for engagement of the cap 20 with the wall portion 27. The advantages of the specific placement of the cap 20 to the wail portion 27 are further discussed below with respect to Figs. 10 - 12.
  • a plurality of recesses may also be employed to effect cap placement positioning as well as for securing the cap 20 to the projecting wall 34.
  • the projecting wall 34 extends outward to a perimeter hold position 38 whereupon the projecting wall turns inwardly and then downwardly and then turning parallel to the base 14 to create a recess 37 for holding the filter media 33.
  • This filter media 33 is placed in the filter media recess 35 where it is enclosed by and securely held by foraminous cap 20.
  • the foraminous cap 20 Attorney Docket No. 20808- WO has a at least one hole and in this depicted embodiment a plurality of holes 21.
  • Cap 20 has a pane! 38 and a continuous cap sidewal! 39 depending therefrom.
  • the cap 20 has a detent 40 which fits into the recess 35 of the projecting wa!l 34 to provide a snap fit.
  • a cap 20 having a pane! 38 and a continuous side wa!i 39 depending therefrom with the sidewail 39 having at feast one detent 40 may be employed to cooperate with the projecting wall 34 to provide snap fit aitachment means.
  • Each detent and recess is adapted to cooperate with each other to provide attachment means whereby a cap 20 is securely connected to the tray wall 1 1 .
  • Fig. 7 a sectional view of a foraminous cap 20 and fray wall portion 27 taken along lines 7-7 of Fig. 6 is shown. In figure 7, the cap 20, filter media 33 and foraminous wai!
  • vent 19 in accordance with the present invention.
  • the solid headed arrows show gas flow between the interior of the tray through openings in the cap 20 provided by a plurality of holes 21 across the fitter media 33 and into and out of openings in the foraminous wall portion 27 provided by a plurality of ho!es 28.
  • vent 19 permits sterilizing gases to be admitted from the tray exterior through holes 28, across the filter media 33 and out of holes 21 into the tray interior whereupon the damaging, dangerous or undesirable microbes, molds, yeasts, spores, viruses, bacteria and the like are eradicated to render contents of an enclosed tray sterile.
  • the sterilant gases are flushed from the tray interior by application of an vacuum and re-admittance of atmospheric or purging gases.
  • This sterilant, vacuum , gas exchange operation may be cycled multiple times to effect sterilization.
  • This process which typically employs ethylene oxide as a sterilant which may be performed under elevated temperatures and with or without elevated humidity can cause changes in pressure or pressure differentials which stress not only lid to tray seals, but also the attachment means for securing the filter media over the openings in the tray wall.
  • the cap 20 may be held mechanically e.g. by snap fit means and/or may also be held by heat seals, ultrasonic welding, adhesives or combinations thereof.
  • FIG. 8 an exploded view of the foraminous cap 20, filter media 33, and tray wall portion 27 of vent 19 depicted in Fig. 7 is shown.
  • the foraminous wail portion 27 of tray wall 1 1 is formed into a shape Attorney Docket No. 20808- WO having a projecting vval! 34 with a recess 35 which is adapted to receive a
  • Portion 27 is further formed to have a f ilter media recess 37 for receiving filter media 33.
  • the cap 20 may be formed with either or both of a recess for receiving the filter media 33 and/or one or more recesses for receiving a corresponding detent which detent could be made in the wall portion e.g. on the interior side of a projecting wall 34 and into which a cap could snap fit in a nesting arrangement.
  • a bottom panel 41 of the wali portion 27 has a plurality of openings which could be slots, ovals, or of various sizes or shapes, but preferably are generally circular holes 28 which may be formed from variety of well-known means e.g. laser perforations, die punched, hot needle formed, etc.
  • the filter media may employ a variety of materials which can range from cellu!osic materials such as cotton to synthetic non-cellulosic polymers such as polypropylene nonwovens, sintered polyethylene discs or open celled foamed polymers, etc.
  • the foraminous cap 20 has a panel 38 through which are provided a plurality of holes 21 as for the wall panel 41 .
  • the dimensions of the filter media recess 37, projecting wali recess 35, cap detent 40 and thickness of the filter media are such that, upon attachment of the cap 20 to the wall portion 27 , the filter media 331s securely held therebetween in a manner which precludes filtration defeating channeling between the holes in the cap 20 and the holes 28 in the wall portion 27.
  • FIG. 9 an alternative vent 219 to the vent 19 depicted In Fig. 7 is shown having a foraminous cap 220, filter media 233, and foraminous tray wall portion 227.
  • the vent 219 is similar to that described above for Figs. 6-8 except that a single opening or hole is used in either or both of the cap 220 and/or wall portion 2:27.
  • a cap 220 having a single hole 221 and a wail portion 227 also having a singie hole 28.
  • This embodiment contemplates use of filter media 233 which is self-contained e.g. a cohesive sintered disk having sufficient integrity that it does not disintegrate in use or a filter media having a woven or nonwoven containing wall e.g. as a sachet or self-contained semi-permeable pouch.
  • FIG. 10-12 an alternative form of the vent 19 of Figs. 6-8 is depicted in the form of a transverse flow vent 319.
  • FIG 10 is a schematic top view of an alternative foraminous cap 320 and tray wall portion 311 in accordance with the present invention.
  • An opening or slot-like hole 323 in foraminous wati portion 327 is shown by dotted line to axialiy offset from the cap opening 321.
  • a single hole is shown in both cap 320 and wa! portion 327, it is contemplated that a plurality of hoies couid be grouped together to achieve the same effect, as further described below.
  • slot hole 321 cou!d be e.g. three holes in a Sine within the same outline of the slot or an array of e.g.
  • 9-12 small holes could be bunched together on one side of the cap 320 while in a similar fashion the single slot 328 of the wali portion 327 could be transformed into a plurality of holes in a line or bunched array yet distalSy located from the cap holes 321.
  • FIG 11 is a sectional view taken along lines 1 1-1 1 of Fig. 10. in this sectional view a similar vent component arrangement to that of vent 19 in Figs. 6-8 are shown except for the openings or holes in the cap 20 and wall portion 27.
  • a tray wall 311 has a foraminous wail portion 327 with the projecting wall 334 having a recess 335 time which is seated filter media 333 held in place by a foraminous cap 320 which is connected to the wail portion 327 by snap fit aitachment means.
  • the cap 320 is provided with at least one detent 340 and the projecting wall 334 has a mating recess 335 to receive the detent 340 thereby providing retention of the cap 320 by pushing and stretching the detent 340 over the projecting wall 334 until it snaps back with the cap detent 340 nesting within the recess 335 of the projecting wall 334 as for the embodiment of Figs. 6-8.
  • the detent and recess are adapted to cooperate to provide the attachment means whereby the cap is securely connected to the tray wall, it should also be noted that the attachment means may be provided by use of an adhesive, heat sealing, ultrasonic welding, mechanical attachment for exampie by snap fit or press that means, or combinations thereof.
  • FIG. 12 is an enlarged schematic view of the cap 320, filter media 333, and an the foraminous tray wall portion 327 defined by the projecting wall 334 as depicted in Fig. 1 1 and the interior space thereof.
  • Fig. 12 illustrates gas movement directions by solid headed arrows.
  • Vent 319 is depicted in Fig. 12 showing a Attorney Docket No. 20808- WO foraminous wall portion 327 having a hoie 328 therethrough in a f irst section within the interior space defined by the projecting wail (See Fig. 1 1 ).
  • a second section which has no openings.
  • the cap 320 has a pane!
  • the cap 320 and iray wall 311 may be secured to the wall portion 327 with the first and second cap sections oriented with respect to the first and second waii portion sections such that a path from opening 328 opening 321 in its shortest distance D R is greater than a path from an interior surface 348 of the cap 320 to an interior surface 347 of the wail portion recess 335 in its shortest distance Dr.
  • the shortest distance Dj also corresponds to the thickness of the filter media 333. in one preferred embodiment, the relationship between these two shortest distances DR and D T wi!i satisfy the formula DR ⁇ 2D T
  • the cap 320 and iray wall 311 may be secured to the wall portion 327 with the first and second cap sections oriented with respect to the first and second waii portion sections such that a path from opening 328 opening 321 in its shortest distance D R is greater than a path from an interior surface 348 of the cap 320 to an interior surface 347 of the wail portion recess 335 in its shortest distance Dr
  • orienting means for positioning opening or hole 328 in a spaced apart relationship to the opening or hole 321 , along a plane of the cap panel 338 or bottom pane! 341 of the wal! portion 327,
  • These orienting means may comprise at !east one of: (i) mating cap and wali portion projecting wail configurations which preclude transverse alignment of openings of the cap 320 with the openings of the foraminous wali portion 327; locating notches or visual indicators in the cap 320 and wali portion 327; and (iii) an asymmetric cap perimeter; and (iv) positioning lock tabs.
  • gas flow may enter o exit opening 321 and proceed longitudinally or transversely through filter media 333 entering or exiting opening 328 to provide a long pathway through the filter media 333.
  • This long transverse flow path advantageously in accordance with the present invention allows for a low profile vent to be provided on a rigid tray where this low-profile vent 319 is capable of providing a high degree of filtration undesirable partic!es and/or organisms while permitting a high gas volume to flow into and out of the tray interior during gas sterilization processes. This helps to prevent seal rupture between the tray and led and aiso around the vent itself.
  • a highly Attorney Docket No. 20808- WO desirable combination of filtration efficiency, effectiveness, and stress reducing gas flow rates.
  • a vented rigid tray indicated generally by 410 having a continuous tray wall 411 with exterior surface 412 and interior surface 413, base 414 and base sidewall 415.
  • the base sidewaSI 415 has a continuous perimeter sidewall flange 416 with an upper flange surface 417.
  • Sidewall 415 is equipped with an internal rim 4 8 for receiving a retainer insert 451.
  • a microbe filter vent 419 is shown in an exploded view having a foraminous cap 420 with holes 421 , filter media 433, and a foraminous wall portion 427 with the projecting wall 434 forming a filter media recess 437.
  • Cap 420 comprises a panel 438 and sidewall 439 which is depicted as having a generally rectangular shape which may be asymmetrical such that the May only be connected to wall portion 427 and a single configuration.
  • Cap 420 may be mechanically fastened wall portion 427 by manually pushing the cap for 20 against the wail portion 427 with filter media 433 therebetween which causes cap sidewall 439 to distort and extend about projecting wall 434 with detent means of the cap 420 springing back into a recess four and 35 of the projecting wall 4 to 34 to securely hold the cap 420 two wall portion 427 with filter media 433 therebetween.
  • an adhesive may be applied to the perimeter surface of the projecting wall 434 which provides upon setting of the adhesive a hermetic seal about the perimeter.
  • An article 450 depicted as a generic plug may be inserted into the tray 410 and secured against movement therein by a projection formed in fray base 414 and by provision of retainer insert 451 having a shaped engagement means for securing the article depicted as rejection 453 whereby the retainer insert 451 is inserted within the tray such that the retainer insert perimeter edge 452 engages tray side wail Internal rim 418.
  • This retainer insert 451 may also be configured to snap fit into a recess adjacent the internal rim 418 on the interior surface 413 of the iray wall 411.
  • the retainer insert may be manually removable which may be facilitated by providing a finger hole opening.
  • a lid 454 which is preferably transparent may be made from a thin film or clear plastic sheet and adhered to or heat sealed or otherwise fastened to the upper flange surface 41 of the tray sidewall flange 416 thereby providing and hermetic seal about the Attorney Docket No. 20808- WO perimeter of the tray for 410 where the id is connected to the tray side wall.
  • the retainer insert 451 may be designed to act as the lid itself and attached by suitable fastening means which may include mechanical fastening means, adhesive, heat seal or combinations thereof.
  • suitable fastening means which may include mechanical fastening means, adhesive, heat seal or combinations thereof.
  • a rigid lid may be utilized in the present invention wherein the filter vent for 419 may be located therein rather than on the tray side wall or base.
  • the tray lid and/or retainer insert acts as an upper tray wall to enclose and seal within the interior of the tray for 410 the article 450 while providing filtration and vent means through the top of the tray via ltd and/or retainer insert.
  • the filtration vent may utilize a material which combines the functionality of the filtration means as part of material forming the cap or foraminous wall portion.
  • a foraminous cap or lid containing the same may be said to be a spring cover whereby the cap or lid has sufficient extensibility to be disiortabie about its perimeter whereby it may be compressed or extended to engage a tray projection or recess to provide mechanical fastening thereto.
  • a spring cover may be provided which comprises filter means for filtering microbes and particulates, and fastening means for connecting said cover to a tray.
  • This spring cover may be a foraminous cap which may be attached as described above either trapping filter media between the cap and a portion of the tray wall having an opening therein or the cap may be formed from filter media itself such as porous sintered po!yolefin.
  • the fastening means for this may be mechanical fastening means, for example, having a perimeter extensible resilient wall which may be pressed over a projection from the tray wall to engage a perimeter cap detent with a recess on the tray wail projection or alternatively may be compressed and fit within a projection from the tray wall to engage a perimeter recess located within that projection such that the cap detent expands to engage the interiorly located internal perimeter recess.
  • the spring cover may be a iid equipped with filter means and said filter means may be the same as the foraminous cap described above.
  • a spring cover lid may be similarly fastened by using a disiortabie perimeter which may be
  • trays that are equipped with a vent and preferred embodiments of such trays may also advantageously provide easy access to remove contents within the tray.
  • the novel trays may be manually opened without use of scissors or other tools, preferably using easy to peel open systems such as peelab!e seals.
  • the lid seal may be either peelable or non-peelabSe,
  • the lid seal is a peelable seal which is peelabie along at least a portion of the seal or along the entire seal to provide access to the tray contents.
  • Peelable sea!” and like terminology is used herein to refer to a seal, and especially heat seals, which are engineered to be readily peelable without uncontrolled or random tearing or rupturing the packaging materials which may result in premature destruction of the package and/or inadvertent contamination or spillage of the contents of the package.
  • a peelabie seal is one that can be manually peeled apart to open the package at the seal without resort to a knife or other implement to tear or rupture the package.
  • Many varieties of peelable seals are known in the art, such as those disclosed in U.S. Pat. No. 4,944,409 (Busche et al.); U.S. Pat. No. 4,875,587 (LuSham et al.); U.S. Pat. No.
  • a non-peetabie seal may also be employed e.g. a strong integral heat seal along either a portion or along the entire perimeter. Such a non ⁇ peelabie seal may be easily opened by tear open features such as notches, and surface weakened areas, or through the use of tools such as scissors, etc..
  • the attachment means between (a) the Attorney Docket No. 20808- WO cap, and (b) the tray wall can be formed by a variety of ways, and may be either removable or permanent. Mechanical fasters such as snap fit attachment or press fit fastening means may be provided by mating detents and recesses with either being located on at least one of the cap and the tray wall. Attachment may also be by a permanent seal.
  • the seal may be formed as a weld heat seal by application of heat and pressure to the cap and tray wall with their respective surfaces in contact with each other for a sufficient time to cause bonding with cooling of the bonded perimeter to form an integral permanent seal.
  • an adhesive can be sandwiched between the cap and tray wall.
  • the lid may be heat sealed to the tray.
  • the cap may be attached to the wall portion by heat sealing.
  • Such seals may have a minimum width of about 1 mm to about 5 mm or more. Preferred widths are from 5 to 15 mm with a typical width being about 8-10 mm.
  • the seal between the lid and tray wall e.g. at a flange may be a permanent seal made by use of a heat seal or permanent adhesive or it may also be removable e.g. by using a peelable seal.
  • the lid seal whether permanent or peeiable, can seal contents within a compartment of a tray with only a small tray wail vent having a gas passageway that filters out unwanted materials such as particles and microbes.
  • the tray is equipped with a gas sterilization vent in a wall or lid, preferably in its rigid wall, which comprises filter media disposed between a foramsnous cap and a tray wall or lid, and so equipped provides a gas sterilization container and barrier to nongaseous particles including biological agents, pathogens, bacteria, viruses, etc.
  • Typical contents for various embodiments of the inventive tray container may include, for example, medical devices, stents, catheters, medical equipment, tools, bandages, surgical supplies, transdermal patches, bandages, wound care products as well as personal care products such as soaps, lotions, skin, nail, and hair care products, cotton balls or swabs, emery boards, contact lenses, hearing aids, identification tags and chips for pets or wildlife, foodstuffs such as spices, herbs, mushrooms, berries, etc.
  • the inventive vented tray may also have applications where rapid venting due to Attorney Docket No. 20808- WO pressure changes is required to equilibrate internal pressure within a package with exterior pressures while achieving or maintaining a barrier to undesirable particles, chemicals, or organisms, etc,
  • vents which are polygons such as hexagons or circular or oval or other curved or linear shapes or combinations thereof may be used.
  • the distance between gas entrance and exit points of the vent is at ieast equa! to or greater than the thickness of the filter material used.
  • the entrance and exit points will be reversible and flo will typically proceed back and forth e.g. in gas sterilization processes where vacuum is applied and then a sterilant gas pumped in foiiowed by vacuum removal for several iterations followed by flushing cycles of vacuum purging and flushing gas to remove the sterilant gases.
  • An description with respect to entrance and exit should be read to include fiow in the reverse direction unless otherwise specially excluded.
  • a tray is formed e.g. by thermoforming and assembled with filter media and cap attached to the tray wail e.g. at its base with an opening in the tray wall and an opening in the adjacent cap.
  • An article is piaced into the internal compartment of the tray through its open top which is then covered with a flexible transparent lid which is sealed to the tray sidewa!l flange, for example, by heat sealing thereby forming a sealed ventable package having only a tortuous path gas vent microbial barrier passageway between the exterior and interior thereof .
  • the sealed tray has only its filter vent providing a gas passageway between the tray compartment and external environment.
  • the vent serves multiple functions; Attorney Docket No. 20808- WO initially, it provides a means for gas transfer into and out of the compartment so thai the compartment interior and the hip imp!ant may be sterilized, in addition, after completion of sterilization, the vent provides a barrier to and/or filters out undesirable material e.g. particles, dust, bacteria, viruses, pathogens, etc. to permit the implant to be transported, stored and handled prior to use without compromising the implant's sterility.
  • the vented tray also permits the package to shipped or subjected to, or maintained in
  • the chamber After introduction of the tray to the gas sterilization chamber, the chamber is closed and the state of the atmosphere around the tray is random air flow with no pressure differential between the interna! compartment and the external environment outside the tray. Airflow through an ingress port and egress port is in equilibrium. Then the sterilization process begins and the ingress port is closed and a vacuum applied to the egress port. Since there are little or no restrictions between the external
  • a sterilizing gas which is typically ethylene oxide (ETO) and/or steam.
  • ETO ethylene oxide
  • the egress means such as an egress port is closed and ETO and/or steam is admitted e.g. through ingress means such as an ingress port.
  • Flushing gases such as nitrogen and also elevated humidit may be employed in these
  • the temperature employed during this process may also be varied to enhance or aid the sterilization process and typically elevated temperatures may be used, but decreased temperatures may also be used as well as a combination thereof.
  • filtration vents capable of quickly transporting large volumes of gas to minimize (i) pressure differential magnitude, and (ii) the length of time at a pressure differential.
  • the time for the sterilization process is impacted because those stresses may be minimized by slowing the rate of change of the pressure or vacuum applied during the process as a means to avoid undue stress on the container. So if a vacuum is applied slowly i.e.
  • filter venting is typically provided by a calendared medical grade paper or a calendared spun bonded polyolefin such as that commercially sold under the brand Tyvek®.
  • This spunbonded material is a very good barrier to passage of microbes and particulates, but requires a large surface area to provide sufficient gas flow across its thickness for efficient use in gas sterilization processes. It is also opaque and non-transparent obscuring the view therethrough.
  • the paper or Tyvek® is used as the lid for the tray or constitutes a large portion of the lid.
  • the softening and melting point temperatures for spunbonded polyolefins used in commercial Tyvek® or a heat seal coating applied thereto are such that heat seals to the material are Attorney Docket No. 20808- WO weakened by exposure to steam heat leading to possible premature seal failure
  • Typical thicknesses of commercially available spun bonded poiyoiefin materials used in sterilizable packaging range from about 6 to 8 mils (152 - 203 ⁇ ). Papers are also sometimes used and have a thickness which ranges from 2 to 6 mils (51 - 152 ⁇ ). Both papers and spunbonded polyolefins such as Tyvek® have significant resistance to transverse gas flow which is inadequate for any utility in small vent devices such as those enabled by the present invention.
  • the key parts of the vented tray according to the invention are; (1 ) a filter media, typically greater than 1/16 inch (1587.5 microns) in thickness, preferably in the form of a thin sheet or disc, that combines: (i) good gas flow (not only across its thickness, but transversely along its length and preferably radially in all directions) with (ii) excellent filtration barrier properties (to arrest, impede and bar transfer of undesired materials between the entrance and exit points of the filter media); (2) a foraminous tray wail portion that covers a desired portion of a filter media surface; and (3) a foraminous cap across the thickness of the filter media from the foraminous tray wall portion and having an opening therethrough.
  • a filter media typically greater than 1/16 inch (1587.5 microns) in thickness, preferably in the form of a thin sheet or disc, that combines: (i) good gas flow (not only across its thickness, but transversely along its length and preferably radially in all directions) with (ii) excellent filtration barrier properties (
  • the position of the cap and tray wall portion and their respective openings or holes are such that a longer transit path than the width of the filter media is formed therebetween.
  • This longer transit path mainly extends radially or transversely to the shortest distance across the filter media thickness.
  • a longer tortuous path may be utilized with a sufficiently open pore structure to preferably both increase gas flow and reduce undesired particle and material transmission between ingress and egress points.
  • a thicker f ilter media than paper Attorney Docket No. 20808- WO or Tyvek €> spunbonded poSyoiefin may be utilized to provide an advantageous combination of high gas flow and excellent filtration barrier properties.
  • gas may transit either or both (1) across the face of a thicker filter media; and (2) between a defined area of a first face of the filter sheet edge and a transversely displaced defined area on the opposing second face of the filter sheet at a point away from the first defined area and therefore resulting in a change of direction of gas flow from an axial entrance point to an offset exit point thus making at least two right angles or 90° turns in general direction from the typical across thickness flow in prior art packaging.
  • the distances employed by the presently disclosed vent technology range from (i) the thickness of a suitabl filter sheet media as for the "across the face" transit method ⁇ 1 ) above where typical distances are at least about 0.062 inches, to transit method (2) having offset openings where typical distances may be from 0.125 inches to 0.375 inches or longer. In comparison to the typical
  • This path may also have at least two 90° turns which facilitate filtration by inertia! impaction.
  • Suitable distance for the gas passageway in the vents of the present invention will be greater than 10 mil (0.010 inch) and typically greater than 50 mi! (0.050 inch), preferably greater than 100 mi! (0.100 inch), more preferably at least 250 mil. As this distance increases a longer tortuous path for filtration is presented with all the advantages presented by greater filtration. Balanced against an increased tortuous path will be the gas flow properties which as described above must be sufficient to Attorney Docket No. 20808- WO withstand the pressure changes to which the package or other article will be subjected. The upper limits may be experimentally determined without undue experimentation based upon other parameters selected Including usage environments e.g. gas sterilization apparatus and processes, transit conditions, and gas flow rates obtainable by different filter media, volumes to be sterilized or held, etc.
  • this distance will be at least double the distance across the narrow dimension of the filter media ⁇ i.e. the thickness).
  • the filtration distance provided by preferred embodiments of the invention which require offset openings in opposing filter vent faces may be from 2, 3, 4, 5, 8, 7, 8, 9, 10 or more times greater in distance than the thickness of the filter media used and over 16 times greater than the thickness of commercially available coated Tyvek®. it may be from 28 to 50 to 83 to 150 times greater than the thicknesses of commercially available papers for gas sterilization packaging.
  • a filter media having an open pored three dimensional tortuous path structure may be utilized with tray walls and lids having low gas permeability, and which also are barriers to other materials including particulates, Attorney Docket No. 20808- WO organisms, bacteria, viruses, etc., to direct the fiow of gases aiong a longer path than the thickness of a thin sheet material, !n this manner several improvements and advantages over the prior art are enabled.
  • These iid, cap, and wall components may be selected to be inert with respect to the package contents and act as a barrier to any other undesired material such as micro-organisms, bacteria, viruses, particulates, dust, etc., Advantageously, it may also be selected to present a smooth, nonabrasive surface which is unlikely to contaminate the contents e.g. by detached or abraded fibers or particles from a coating.
  • a longer tortuous path may be used to provide excellent filtration while utilizing increased pore sizes.
  • gases are directed over a longer path and preferably lengthwise and radially from a line representing the shortest distance across the filter media thickness.
  • the thickness of the vent is kept small, typicaliy sizes under 125 mils (3.2 mm) in thickness, and preferably from about 60 to 125 mils (15-3.2 mm).
  • the filter media sheet thickness may range as thin as is consistent with the volume of gas and gas flow rate that is needed for conditions of use. It is contemplated that thicknesses as low as 100 microns will be suitable. Of course larger thicknesses than 125 mil could be employed, but typically there will be no offsetting advantage to do so.
  • the vent will not interfere with the tray contents, content loading and removal with be unhindered and there will be less likelihood of abrasion or detachment by frictional forces. Also, more trays may be held within a given unit space.
  • the distance from the perimeter of the section Attorney Docket No. 20808- WO containing the openings in the cap and the perimeter of the section containing the openings in the foraminous tray wail portion is greater than the filter thickness between the cap and tray wall portion.
  • the present invention utilizes three dimensional gas flow provided by open celled materials such as sintered open celled polymers and an open celled foamed polymers and plastics,
  • a transparent lid may be employed to provide an unobstructed view of the tray contents.
  • a transparent lid may also be combined with a transparent tray and/or insert.
  • the present invention may see an improvement in one or more of the above properties.
  • Preferred embodiments of the invention will have a combination of improved properties.
  • the inventive vented tray may increase air flow rates while maintaining or increasing filtration against passage of unwanted materials while providing a protective filter cover on the package interior and do this in a smaller space and using less material than presently employed in commercial packaging e.g. for medical devices and suppiies.
  • the present invention in its various embodiments finds particular utility in providing packaging for a product which undergoes gas sterilization such as a medical device such as an implantable joint, catheter etc. , or for personal care items such as cotton swabs, cosmetics, etc., or for foodstuffs such as spices, mushrooms, or berries, etc.
  • a product which undergoes gas sterilization such as a medical device such as an implantable joint, catheter etc.
  • personal care items such as cotton swabs, cosmetics, etc.
  • foodstuffs such as spices, mushrooms, or berries, etc.
  • the present invention permits smaller sized filter vents to be used at a materia! cost savings while maintaining and enhancing protection of enclosed products from damage and contamination during transportation through zones of pressure differentials such as those found in gas sterilization operations, !t also provides enhanced visibilit to tray contents.
  • a vented rigid tray for gas sterilization comprising:
  • attachment means for the foraminous cap and the tray wall whereby the filter media is held between the cap and the foraminous wall portion e.g. by snap fit or press fit mechanical fastening, adhesives, heat seals, ultrasonic welding, or combinations thereof.
  • a rigid tray as defined in embodiments 1-39, wherein the foraminous wa!l portion is in the base.
  • a rigid tray as defined in embodiments 1-39, wherein the base sidewa!i has a heat sealable lid receiving flange.
  • a rigid tray as defined in embodiments 1-39, wherein the tray is thermoplastic or thermosetting.
  • a rigid tray as defined in embodiments 1-39, wherein the iray is transparent.
  • a rigid tray as defined in embodiments 1-39, wherein the tray wall is thernioformed or injection molded.
  • a rigid tray as defined in embodiments 1-39, wherein the foraminous wall portion has a continuous projecting wali proximate to and surrounding the portion.
  • a rigid tray as defined in embodiments 8-39, wherein the projecting wall extends from the tray wall towards the tray exterior.
  • a rigid tray as defined in embodiments 8-39, wherein the projecting wall extends from the tray wail towards the tray interior.
  • a rigid tray as defined in embodiments 8-39, wherein the cap has a panel and a continuous sidewall depending therefrom with the cap sidewall having at least one detent which cooperates with the projecting wall to provide the snap fit attachment means and optionally the cap may be formed of a foraminous material such as sintered porous polyolefin forming a cap which functions as a filter itself.
  • a rigid fray as defined in embodiments 8-39, wherein the cap is provided with at least one detent and the projecting wall has at least one recess, each the detent and recess are adapted to cooperate to provide the attachment means whereby the cap is securely connected to the tray wail.
  • a rigid tray as defined in embodiments 8-39, wherein (i) the wall portion has one or more openings (A) therethrough in a first section within an interior space defined by the projecting wall and has no openings within a second section which is also within the interior space defined by the projecting wali; and (ii) the cap has a panel and a Attorney Docket No.
  • 20808- WO continuous sidewaSI depending therefrom and has one or more openings (8) through the panel in a first section within an interior space defined by the continuous sidewall and has no openings within a second section which is also within the interior space defined by the continuous sidewall; and (iii) wherein the cap is secured to the wall portion with the first and second cap sections oriented with respect to the first and second wail portion sections such that a path from openings A to openings B in its shortest distance D R is greater than a path from an interior surface of the cap pane! to an interior surface of the wall portion circumscribed by the projecting wall in its shortest distance D .
  • a rigid tray as defined in embodiments 13-39, wherein D R ⁇ 2D T .
  • a rigid tray as defined in embodiments 13-39, wherein the cap and the tray wail have orienting means for positioning the openings 8 in a spaced apart relationship, along a plane of the cap pane!, to openings A.
  • a rigid tray as defined in embodiments 1 -39, further comprising an article located within an interior surface of the tray and a transparent iid attached to the sidewall by a continuous seal.
  • a rigid tray as defined in embodiments 1 -39 wherein a transparent iid provides an unobstructed view of an enclosed article.
  • a pharmaceutical product a personal care product or a foodstuff.
  • a rigid tray as defined in embodimenis 1-39, wherein the filter media comprises: air Said, wet laid or dry Said nonwovens; polypropylene, polyethylene, polyester, nylon, cellulose fibers or permeable sheets; cotton; sintered porous polymers; open
  • a rigid tray as defined in embodimenis 1 -39, wherein the synthetic polymer tray wail comprises a mono! a er or multilayer structure.
  • a rigid tray as defined in embodiments 1-39, wherein the synthetic polymer tray wail comprises a po!yo!efin. polyester, poiyureihane, polystyrene, cyclic olefin copolymer, a porous sintered polymer, or combinations thereof.
  • PET polyester terephthalate
  • aPET amorphous PET
  • PETg glycol modified PET
  • H!PS high impact polystyrene
  • HOPE high density polyethylene
  • a rigid tray as defined in embodiments 1-39, wherein the synthetic polymer tray wail comprises a multilayer structure having at least one layer of polyester terephthalate (PET) homopolymer or copolymer, and an interior surface layer comprising poiyureihane.
  • PET polyester terephthalate
  • a rigid tray as defined in embodiments 1-39, wherein the synthetic polymer tray wail comprises a multilayer structure having an interior surface layer comprising poiyureihane or a cyclic olefin copolymer.
  • a rigid tray a defined in embodiments 1-39, wherein the fitter media is greater than 100 mil (2540 u) in thickness.
  • a rigid tray as defined in embodimenis 1 -39, wherein the filter media has a gas path distance greater than a minimum thickness of the filter media.
  • a rigid tray as defined in embodiments 1 -39, wherein the gas path is at least 10 mil (254 ⁇ ) in length, preferably at least 100 mii (2540 ⁇ ), and more preferably at least 200 mil (5080 ⁇ ).
  • a rigid tray as defined in embodiments 1-39, wherein the fitter media has a three dimensional open ceil structure.
  • a rigid tray as defined in embodiments 1 -39, wherein the filter media comprises a sintered porous polyolefin and optionally the filter media comprises the foraminous cap.
  • a rigid tray as defined in embodiments 1-39, wherein the filter media comprises an open celled foamed polymer.
  • a rigid tray as defined in embodiments 1-39, wherein the filter media comprises a fibrous polypropylene mat.
  • a rigid tray as defined in embodiments 1 -39, wherein the filter media comprises a sintered porous polyethylene,
  • a rigid tray as defined in embodiments 1-39, wherein the fitter media has a pore size between 15-50 microns.
  • a rigid tray as defined in embodiments 1-39, wherein the filter media further comprises

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Abstract

La présente invention se rapporte à une barquette rigide à évent qui est destinée à la stérilisation par gaz et qui comprend : (a) une paroi de barquette en polymère synthétique qui comporte des surfaces extérieure et intérieure, une base et une paroi latérale droite, une partie de paroi foraminée se situant dans la base et/ou la paroi latérale ; (b) une couche filtrante ; (c) un capuchon foraminé ; et (d) un moyen de fixation par encliquetage pour le capuchon foraminé et la paroi de barquette, la couche filtrante étant maintenue entre le capuchon et la partie de paroi foraminée.
PCT/US2013/070722 2013-11-19 2013-11-19 Barquette de conditionnement rigide à évent destinée à la stérilisation par gaz Ceased WO2015076780A1 (fr)

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Cited By (334)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108136103A (zh) * 2015-09-29 2018-06-08 泰尔茂株式会社 医疗用具包装用容器、医疗用具包装体及预灌封注射器用外筒包装体
CN111202587A (zh) * 2018-11-21 2020-05-29 海隆医用产品(昆山)有限公司 一种可加热塑料盆
EP3756611A1 (fr) * 2019-06-28 2020-12-30 Ethicon LLC Ensemble de conditionnement comprenant un piège à particules
US20210015579A1 (en) * 2018-03-30 2021-01-21 Bemis Company, Inc. Package for pvc products
WO2021080895A1 (fr) * 2019-10-21 2021-04-29 Covestro Llc Matériaux de conditionnement orthopédique
US11045189B2 (en) 2008-09-23 2021-06-29 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US11051810B2 (en) 2016-04-15 2021-07-06 Cilag Gmbh International Modular surgical instrument with configurable operating mode
US11051813B2 (en) 2006-01-31 2021-07-06 Cilag Gmbh International Powered surgical instruments with firing system lockout arrangements
US11058422B2 (en) 2015-12-30 2021-07-13 Cilag Gmbh International Mechanisms for compensating for battery pack failure in powered surgical instruments
US11071543B2 (en) 2017-12-15 2021-07-27 Cilag Gmbh International Surgical end effectors with clamping assemblies configured to increase jaw aperture ranges
US11071545B2 (en) 2014-09-05 2021-07-27 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11076853B2 (en) 2017-12-21 2021-08-03 Cilag Gmbh International Systems and methods of displaying a knife position during transection for a surgical instrument
US11076854B2 (en) 2014-09-05 2021-08-03 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11076929B2 (en) 2015-09-25 2021-08-03 Cilag Gmbh International Implantable adjunct systems for determining adjunct skew
US11083456B2 (en) 2004-07-28 2021-08-10 Cilag Gmbh International Articulating surgical instrument incorporating a two-piece firing mechanism
US11083454B2 (en) 2015-12-30 2021-08-10 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11083453B2 (en) 2014-12-18 2021-08-10 Cilag Gmbh International Surgical stapling system including a flexible firing actuator and lateral buckling supports
US11083457B2 (en) 2012-06-28 2021-08-10 Cilag Gmbh International Surgical instrument system including replaceable end effectors
US11083455B2 (en) 2017-06-28 2021-08-10 Cilag Gmbh International Surgical instrument comprising an articulation system ratio
US11090075B2 (en) 2017-10-30 2021-08-17 Cilag Gmbh International Articulation features for surgical end effector
US11090049B2 (en) 2017-06-27 2021-08-17 Cilag Gmbh International Staple forming pocket arrangements
US11090045B2 (en) 2005-08-31 2021-08-17 Cilag Gmbh International Staple cartridges for forming staples having differing formed staple heights
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US11090048B2 (en) 2016-12-21 2021-08-17 Cilag Gmbh International Method for resetting a fuse of a surgical instrument shaft
US11103269B2 (en) 2006-01-31 2021-08-31 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11103241B2 (en) 2008-09-23 2021-08-31 Cilag Gmbh International Motor-driven surgical cutting instrument
US11109859B2 (en) 2015-03-06 2021-09-07 Cilag Gmbh International Surgical instrument comprising a lockable battery housing
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US11135352B2 (en) 2004-07-28 2021-10-05 Cilag Gmbh International End effector including a gradually releasable medical adjunct
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US11134944B2 (en) 2017-10-30 2021-10-05 Cilag Gmbh International Surgical stapler knife motion controls
US11134938B2 (en) 2007-06-04 2021-10-05 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11134943B2 (en) 2007-01-10 2021-10-05 Cilag Gmbh International Powered surgical instrument including a control unit and sensor
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US11147554B2 (en) 2016-04-18 2021-10-19 Cilag Gmbh International Surgical instrument system comprising a magnetic lockout
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US11154301B2 (en) 2015-02-27 2021-10-26 Cilag Gmbh International Modular stapling assembly
US11154296B2 (en) 2010-09-30 2021-10-26 Cilag Gmbh International Anvil layer attached to a proximal end of an end effector
US11154297B2 (en) 2008-02-15 2021-10-26 Cilag Gmbh International Layer arrangements for surgical staple cartridges
US11160551B2 (en) 2016-12-21 2021-11-02 Cilag Gmbh International Articulatable surgical stapling instruments
US11160553B2 (en) 2016-12-21 2021-11-02 Cilag Gmbh International Surgical stapling systems
US11166717B2 (en) 2006-01-31 2021-11-09 Cilag Gmbh International Surgical instrument with firing lockout
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US11179150B2 (en) 2016-04-15 2021-11-23 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US11185325B2 (en) 2014-10-16 2021-11-30 Cilag Gmbh International End effector including different tissue gaps
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US11202633B2 (en) 2014-09-26 2021-12-21 Cilag Gmbh International Surgical stapling buttresses and adjunct materials
US11207065B2 (en) 2018-08-20 2021-12-28 Cilag Gmbh International Method for fabricating surgical stapler anvils
US11207064B2 (en) 2011-05-27 2021-12-28 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US11213293B2 (en) 2016-02-09 2022-01-04 Cilag Gmbh International Articulatable surgical instruments with single articulation link arrangements
US11213302B2 (en) 2017-06-20 2022-01-04 Cilag Gmbh International Method for closed loop control of motor velocity of a surgical stapling and cutting instrument
US11224423B2 (en) 2015-03-06 2022-01-18 Cilag Gmbh International Smart sensors with local signal processing
US11224426B2 (en) 2016-02-12 2022-01-18 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11224497B2 (en) 2019-06-28 2022-01-18 Cilag Gmbh International Surgical systems with multiple RFID tags
US11224428B2 (en) 2016-12-21 2022-01-18 Cilag Gmbh International Surgical stapling systems
US11224427B2 (en) 2006-01-31 2022-01-18 Cilag Gmbh International Surgical stapling system including a console and retraction assembly
US11229437B2 (en) 2019-06-28 2022-01-25 Cilag Gmbh International Method for authenticating the compatibility of a staple cartridge with a surgical instrument
US11234698B2 (en) 2019-12-19 2022-02-01 Cilag Gmbh International Stapling system comprising a clamp lockout and a firing lockout
US11241230B2 (en) 2012-06-28 2022-02-08 Cilag Gmbh International Clip applier tool for use with a robotic surgical system
US11246618B2 (en) 2013-03-01 2022-02-15 Cilag Gmbh International Surgical instrument soft stop
US11246592B2 (en) 2017-06-28 2022-02-15 Cilag Gmbh International Surgical instrument comprising an articulation system lockable to a frame
US11246678B2 (en) 2019-06-28 2022-02-15 Cilag Gmbh International Surgical stapling system having a frangible RFID tag
US11246590B2 (en) 2005-08-31 2022-02-15 Cilag Gmbh International Staple cartridge including staple drivers having different unfired heights
US11253254B2 (en) 2019-04-30 2022-02-22 Cilag Gmbh International Shaft rotation actuator on a surgical instrument
US11253256B2 (en) 2018-08-20 2022-02-22 Cilag Gmbh International Articulatable motor powered surgical instruments with dedicated articulation motor arrangements
US11259803B2 (en) 2019-06-28 2022-03-01 Cilag Gmbh International Surgical stapling system having an information encryption protocol
US11259799B2 (en) 2014-03-26 2022-03-01 Cilag Gmbh International Interface systems for use with surgical instruments
US11259805B2 (en) 2017-06-28 2022-03-01 Cilag Gmbh International Surgical instrument comprising firing member supports
US11266409B2 (en) 2014-04-16 2022-03-08 Cilag Gmbh International Fastener cartridge comprising a sled including longitudinally-staggered ramps
US11266406B2 (en) 2013-03-14 2022-03-08 Cilag Gmbh International Control systems for surgical instruments
US11266405B2 (en) 2017-06-27 2022-03-08 Cilag Gmbh International Surgical anvil manufacturing methods
US11272938B2 (en) 2006-06-27 2022-03-15 Cilag Gmbh International Surgical instrument including dedicated firing and retraction assemblies
US11278279B2 (en) 2006-01-31 2022-03-22 Cilag Gmbh International Surgical instrument assembly
US11284953B2 (en) 2017-12-19 2022-03-29 Cilag Gmbh International Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly
US11284891B2 (en) 2016-04-15 2022-03-29 Cilag Gmbh International Surgical instrument with multiple program responses during a firing motion
US11291451B2 (en) 2019-06-28 2022-04-05 Cilag Gmbh International Surgical instrument with battery compatibility verification functionality
US11291441B2 (en) 2007-01-10 2022-04-05 Cilag Gmbh International Surgical instrument with wireless communication between control unit and remote sensor
US11291449B2 (en) 2009-12-24 2022-04-05 Cilag Gmbh International Surgical cutting instrument that analyzes tissue thickness
US11291447B2 (en) 2019-12-19 2022-04-05 Cilag Gmbh International Stapling instrument comprising independent jaw closing and staple firing systems
US11291440B2 (en) 2018-08-20 2022-04-05 Cilag Gmbh International Method for operating a powered articulatable surgical instrument
US11298125B2 (en) 2010-09-30 2022-04-12 Cilag Gmbh International Tissue stapler having a thickness compensator
US11298132B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Inlernational Staple cartridge including a honeycomb extension
US11298127B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Interational Surgical stapling system having a lockout mechanism for an incompatible cartridge
US11304695B2 (en) 2017-08-03 2022-04-19 Cilag Gmbh International Surgical system shaft interconnection
US11304696B2 (en) 2019-12-19 2022-04-19 Cilag Gmbh International Surgical instrument comprising a powered articulation system
US11311292B2 (en) 2016-04-15 2022-04-26 Cilag Gmbh International Surgical instrument with detection sensors
US11311294B2 (en) 2014-09-05 2022-04-26 Cilag Gmbh International Powered medical device including measurement of closure state of jaws
US11311290B2 (en) 2017-12-21 2022-04-26 Cilag Gmbh International Surgical instrument comprising an end effector dampener
US11317917B2 (en) 2016-04-18 2022-05-03 Cilag Gmbh International Surgical stapling system comprising a lockable firing assembly
US11317913B2 (en) 2016-12-21 2022-05-03 Cilag Gmbh International Lockout arrangements for surgical end effectors and replaceable tool assemblies
US11324501B2 (en) 2018-08-20 2022-05-10 Cilag Gmbh International Surgical stapling devices with improved closure members
US11324503B2 (en) 2017-06-27 2022-05-10 Cilag Gmbh International Surgical firing member arrangements
US11337693B2 (en) 2007-03-15 2022-05-24 Cilag Gmbh International Surgical stapling instrument having a releasable buttress material
US11337698B2 (en) 2014-11-06 2022-05-24 Cilag Gmbh International Staple cartridge comprising a releasable adjunct material
US11344303B2 (en) 2016-02-12 2022-05-31 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11344299B2 (en) 2015-09-23 2022-05-31 Cilag Gmbh International Surgical stapler having downstream current-based motor control
US11350929B2 (en) 2007-01-10 2022-06-07 Cilag Gmbh International Surgical instrument with wireless communication between control unit and sensor transponders
US11350935B2 (en) 2016-12-21 2022-06-07 Cilag Gmbh International Surgical tool assemblies with closure stroke reduction features
US11350928B2 (en) 2016-04-18 2022-06-07 Cilag Gmbh International Surgical instrument comprising a tissue thickness lockout and speed control system
US11350932B2 (en) 2016-04-15 2022-06-07 Cilag Gmbh International Surgical instrument with improved stop/start control during a firing motion
US11350843B2 (en) 2015-03-06 2022-06-07 Cilag Gmbh International Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US11350916B2 (en) 2006-01-31 2022-06-07 Cilag Gmbh International Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
EP4015071A1 (fr) * 2020-12-17 2022-06-22 Zobele Holding SpA Récipient pour la diffusion de substances volatiles
US11376098B2 (en) 2019-06-28 2022-07-05 Cilag Gmbh International Surgical instrument system comprising an RFID system
US11382638B2 (en) 2017-06-20 2022-07-12 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified displacement distance
US11382626B2 (en) 2006-10-03 2022-07-12 Cilag Gmbh International Surgical system including a knife bar supported for rotational and axial travel
US11382627B2 (en) 2014-04-16 2022-07-12 Cilag Gmbh International Surgical stapling assembly comprising a firing member including a lateral extension
US11382628B2 (en) 2014-12-10 2022-07-12 Cilag Gmbh International Articulatable surgical instrument system
US11395652B2 (en) 2013-04-16 2022-07-26 Cilag Gmbh International Powered surgical stapler
US11399831B2 (en) 2014-12-18 2022-08-02 Cilag Gmbh International Drive arrangements for articulatable surgical instruments
US11399828B2 (en) 2005-08-31 2022-08-02 Cilag Gmbh International Fastener cartridge assembly comprising a fixed anvil and different staple heights
US11399829B2 (en) 2017-09-29 2022-08-02 Cilag Gmbh International Systems and methods of initiating a power shutdown mode for a surgical instrument
US11399837B2 (en) 2019-06-28 2022-08-02 Cilag Gmbh International Mechanisms for motor control adjustments of a motorized surgical instrument
US11406378B2 (en) 2012-03-28 2022-08-09 Cilag Gmbh International Staple cartridge comprising a compressible tissue thickness compensator
US11406380B2 (en) 2008-09-23 2022-08-09 Cilag Gmbh International Motorized surgical instrument
US11419606B2 (en) 2016-12-21 2022-08-23 Cilag Gmbh International Shaft assembly comprising a clutch configured to adapt the output of a rotary firing member to two different systems
US11426251B2 (en) 2019-04-30 2022-08-30 Cilag Gmbh International Articulation directional lights on a surgical instrument
US11426167B2 (en) 2019-06-28 2022-08-30 Cilag Gmbh International Mechanisms for proper anvil attachment surgical stapling head assembly
US11432816B2 (en) 2019-04-30 2022-09-06 Cilag Gmbh International Articulation pin for a surgical instrument
US11439470B2 (en) 2011-05-27 2022-09-13 Cilag Gmbh International Robotically-controlled surgical instrument with selectively articulatable end effector
US11446029B2 (en) 2019-12-19 2022-09-20 Cilag Gmbh International Staple cartridge comprising projections extending from a curved deck surface
US11446034B2 (en) 2008-02-14 2022-09-20 Cilag Gmbh International Surgical stapling assembly comprising first and second actuation systems configured to perform different functions
US11452526B2 (en) 2020-10-29 2022-09-27 Cilag Gmbh International Surgical instrument comprising a staged voltage regulation start-up system
US11452528B2 (en) 2019-04-30 2022-09-27 Cilag Gmbh International Articulation actuators for a surgical instrument
US11457918B2 (en) 2014-10-29 2022-10-04 Cilag Gmbh International Cartridge assemblies for surgical staplers
US11464601B2 (en) 2019-06-28 2022-10-11 Cilag Gmbh International Surgical instrument comprising an RFID system for tracking a movable component
US11464514B2 (en) 2008-02-14 2022-10-11 Cilag Gmbh International Motorized surgical stapling system including a sensing array
US11464513B2 (en) 2012-06-28 2022-10-11 Cilag Gmbh International Surgical instrument system including replaceable end effectors
USD966512S1 (en) 2020-06-02 2022-10-11 Cilag Gmbh International Staple cartridge
US11464512B2 (en) 2019-12-19 2022-10-11 Cilag Gmbh International Staple cartridge comprising a curved deck surface
US11471157B2 (en) 2019-04-30 2022-10-18 Cilag Gmbh International Articulation control mapping for a surgical instrument
US11471155B2 (en) 2017-08-03 2022-10-18 Cilag Gmbh International Surgical system bailout
USD967421S1 (en) 2020-06-02 2022-10-18 Cilag Gmbh International Staple cartridge
US11478247B2 (en) 2010-07-30 2022-10-25 Cilag Gmbh International Tissue acquisition arrangements and methods for surgical stapling devices
US11478244B2 (en) 2017-10-31 2022-10-25 Cilag Gmbh International Cartridge body design with force reduction based on firing completion
US11478241B2 (en) 2019-06-28 2022-10-25 Cilag Gmbh International Staple cartridge including projections
US11478242B2 (en) 2017-06-28 2022-10-25 Cilag Gmbh International Jaw retainer arrangement for retaining a pivotable surgical instrument jaw in pivotable retaining engagement with a second surgical instrument jaw
US11484307B2 (en) 2008-02-14 2022-11-01 Cilag Gmbh International Loading unit coupleable to a surgical stapling system
US11484311B2 (en) 2005-08-31 2022-11-01 Cilag Gmbh International Staple cartridge comprising a staple driver arrangement
US11484312B2 (en) 2005-08-31 2022-11-01 Cilag Gmbh International Staple cartridge comprising a staple driver arrangement
US11490889B2 (en) 2015-09-23 2022-11-08 Cilag Gmbh International Surgical stapler having motor control based on an electrical parameter related to a motor current
US11497488B2 (en) 2014-03-26 2022-11-15 Cilag Gmbh International Systems and methods for controlling a segmented circuit
US11497492B2 (en) 2019-06-28 2022-11-15 Cilag Gmbh International Surgical instrument including an articulation lock
US11504122B2 (en) 2019-12-19 2022-11-22 Cilag Gmbh International Surgical instrument comprising a nested firing member
US11504116B2 (en) 2011-04-29 2022-11-22 Cilag Gmbh International Layer of material for a surgical end effector
EP4091950A1 (fr) * 2021-05-18 2022-11-23 Gerresheimer Glas GmbH Récipient pour unités d'emballage
US11510671B2 (en) 2012-06-28 2022-11-29 Cilag Gmbh International Firing system lockout arrangements for surgical instruments
US11517325B2 (en) 2017-06-20 2022-12-06 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured displacement distance traveled over a specified time interval
US11517311B2 (en) 2014-12-18 2022-12-06 Cilag Gmbh International Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US11517390B2 (en) 2020-10-29 2022-12-06 Cilag Gmbh International Surgical instrument comprising a limited travel switch
US11523823B2 (en) 2016-02-09 2022-12-13 Cilag Gmbh International Surgical instruments with non-symmetrical articulation arrangements
US11523822B2 (en) 2019-06-28 2022-12-13 Cilag Gmbh International Battery pack including a circuit interrupter
US11523821B2 (en) 2014-09-26 2022-12-13 Cilag Gmbh International Method for creating a flexible staple line
US11529142B2 (en) 2010-10-01 2022-12-20 Cilag Gmbh International Surgical instrument having a power control circuit
US11529139B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Motor driven surgical instrument
US11529138B2 (en) 2013-03-01 2022-12-20 Cilag Gmbh International Powered surgical instrument including a rotary drive screw
US11529137B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Staple cartridge comprising driver retention members
US11534259B2 (en) 2020-10-29 2022-12-27 Cilag Gmbh International Surgical instrument comprising an articulation indicator
USD974560S1 (en) 2020-06-02 2023-01-03 Cilag Gmbh International Staple cartridge
USD975278S1 (en) 2020-06-02 2023-01-10 Cilag Gmbh International Staple cartridge
US11547404B2 (en) 2014-12-18 2023-01-10 Cilag Gmbh International Surgical instrument assembly comprising a flexible articulation system
USD975850S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
US11553916B2 (en) 2015-09-30 2023-01-17 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
USD975851S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
US11553971B2 (en) 2019-06-28 2023-01-17 Cilag Gmbh International Surgical RFID assemblies for display and communication
US11559304B2 (en) 2019-12-19 2023-01-24 Cilag Gmbh International Surgical instrument comprising a rapid closure mechanism
US11559496B2 (en) 2010-09-30 2023-01-24 Cilag Gmbh International Tissue thickness compensator configured to redistribute compressive forces
USD976401S1 (en) 2020-06-02 2023-01-24 Cilag Gmbh International Staple cartridge
US11564682B2 (en) 2007-06-04 2023-01-31 Cilag Gmbh International Surgical stapler device
US11564686B2 (en) 2017-06-28 2023-01-31 Cilag Gmbh International Surgical shaft assemblies with flexible interfaces
US11571215B2 (en) 2010-09-30 2023-02-07 Cilag Gmbh International Layer of material for a surgical end effector
US11571212B2 (en) 2008-02-14 2023-02-07 Cilag Gmbh International Surgical stapling system including an impedance sensor
US11571231B2 (en) 2006-09-29 2023-02-07 Cilag Gmbh International Staple cartridge having a driver for driving multiple staples
US11576672B2 (en) 2019-12-19 2023-02-14 Cilag Gmbh International Surgical instrument comprising a closure system including a closure member and an opening member driven by a drive screw
US11583279B2 (en) 2008-10-10 2023-02-21 Cilag Gmbh International Powered surgical cutting and stapling apparatus with manually retractable firing system
USD980425S1 (en) 2020-10-29 2023-03-07 Cilag Gmbh International Surgical instrument assembly
US11607239B2 (en) 2016-04-15 2023-03-21 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US11607219B2 (en) 2019-12-19 2023-03-21 Cilag Gmbh International Staple cartridge comprising a detachable tissue cutting knife
US11612394B2 (en) 2011-05-27 2023-03-28 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US11612393B2 (en) 2006-01-31 2023-03-28 Cilag Gmbh International Robotically-controlled end effector
US11617577B2 (en) 2020-10-29 2023-04-04 Cilag Gmbh International Surgical instrument comprising a sensor configured to sense whether an articulation drive of the surgical instrument is actuatable
US11622766B2 (en) 2012-06-28 2023-04-11 Cilag Gmbh International Empty clip cartridge lockout
US11622763B2 (en) 2013-04-16 2023-04-11 Cilag Gmbh International Stapling assembly comprising a shiftable drive
US11627960B2 (en) 2020-12-02 2023-04-18 Cilag Gmbh International Powered surgical instruments with smart reload with separately attachable exteriorly mounted wiring connections
US11627959B2 (en) 2019-06-28 2023-04-18 Cilag Gmbh International Surgical instruments including manual and powered system lockouts
US11638587B2 (en) 2019-06-28 2023-05-02 Cilag Gmbh International RFID identification systems for surgical instruments
US11638582B2 (en) 2020-07-28 2023-05-02 Cilag Gmbh International Surgical instruments with torsion spine drive arrangements
US11642128B2 (en) 2017-06-28 2023-05-09 Cilag Gmbh International Method for articulating a surgical instrument
US11642125B2 (en) 2016-04-15 2023-05-09 Cilag Gmbh International Robotic surgical system including a user interface and a control circuit
US11648005B2 (en) 2008-09-23 2023-05-16 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US11648009B2 (en) 2019-04-30 2023-05-16 Cilag Gmbh International Rotatable jaw tip for a surgical instrument
US11653914B2 (en) 2017-06-20 2023-05-23 Cilag Gmbh International Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument according to articulation angle of end effector
US11653920B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Powered surgical instruments with communication interfaces through sterile barrier
US11653915B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Surgical instruments with sled location detection and adjustment features
US11660163B2 (en) 2019-06-28 2023-05-30 Cilag Gmbh International Surgical system with RFID tags for updating motor assembly parameters
US11672532B2 (en) 2017-06-20 2023-06-13 Cilag Gmbh International Techniques for adaptive control of motor velocity of a surgical stapling and cutting instrument
US11678882B2 (en) 2020-12-02 2023-06-20 Cilag Gmbh International Surgical instruments with interactive features to remedy incidental sled movements
US11678877B2 (en) 2014-12-18 2023-06-20 Cilag Gmbh International Surgical instrument including a flexible support configured to support a flexible firing member
US11684360B2 (en) 2010-09-30 2023-06-27 Cilag Gmbh International Staple cartridge comprising a variable thickness compressible portion
US11684434B2 (en) 2019-06-28 2023-06-27 Cilag Gmbh International Surgical RFID assemblies for instrument operational setting control
US11690623B2 (en) 2015-09-30 2023-07-04 Cilag Gmbh International Method for applying an implantable layer to a fastener cartridge
US11696761B2 (en) 2019-03-25 2023-07-11 Cilag Gmbh International Firing drive arrangements for surgical systems
US11696757B2 (en) 2021-02-26 2023-07-11 Cilag Gmbh International Monitoring of internal systems to detect and track cartridge motion status
US11701113B2 (en) 2021-02-26 2023-07-18 Cilag Gmbh International Stapling instrument comprising a separate power antenna and a data transfer antenna
US11701111B2 (en) 2019-12-19 2023-07-18 Cilag Gmbh International Method for operating a surgical stapling instrument
US11707273B2 (en) 2012-06-15 2023-07-25 Cilag Gmbh International Articulatable surgical instrument comprising a firing drive
US11717291B2 (en) 2021-03-22 2023-08-08 Cilag Gmbh International Staple cartridge comprising staples configured to apply different tissue compression
US11717294B2 (en) 2014-04-16 2023-08-08 Cilag Gmbh International End effector arrangements comprising indicators
US11717285B2 (en) 2008-02-14 2023-08-08 Cilag Gmbh International Surgical cutting and fastening instrument having RF electrodes
US11717289B2 (en) 2020-10-29 2023-08-08 Cilag Gmbh International Surgical instrument comprising an indicator which indicates that an articulation drive is actuatable
US11723662B2 (en) 2021-05-28 2023-08-15 Cilag Gmbh International Stapling instrument comprising an articulation control display
US11723658B2 (en) 2021-03-22 2023-08-15 Cilag Gmbh International Staple cartridge comprising a firing lockout
US11723657B2 (en) 2021-02-26 2023-08-15 Cilag Gmbh International Adjustable communication based on available bandwidth and power capacity
US11730473B2 (en) 2021-02-26 2023-08-22 Cilag Gmbh International Monitoring of manufacturing life-cycle
US11737749B2 (en) 2021-03-22 2023-08-29 Cilag Gmbh International Surgical stapling instrument comprising a retraction system
US11737754B2 (en) 2010-09-30 2023-08-29 Cilag Gmbh International Surgical stapler with floating anvil
US11737751B2 (en) 2020-12-02 2023-08-29 Cilag Gmbh International Devices and methods of managing energy dissipated within sterile barriers of surgical instrument housings
US11744603B2 (en) 2021-03-24 2023-09-05 Cilag Gmbh International Multi-axis pivot joints for surgical instruments and methods for manufacturing same
US11749877B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Stapling instrument comprising a signal antenna
US11744581B2 (en) 2020-12-02 2023-09-05 Cilag Gmbh International Powered surgical instruments with multi-phase tissue treatment
US11744583B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Distal communication array to tune frequency of RF systems
US11751869B2 (en) 2021-02-26 2023-09-12 Cilag Gmbh International Monitoring of multiple sensors over time to detect moving characteristics of tissue
US11759202B2 (en) 2021-03-22 2023-09-19 Cilag Gmbh International Staple cartridge comprising an implantable layer
US11766260B2 (en) 2016-12-21 2023-09-26 Cilag Gmbh International Methods of stapling tissue
US11766259B2 (en) 2016-12-21 2023-09-26 Cilag Gmbh International Method of deforming staples from two different types of staple cartridges with the same surgical stapling instrument
US11766258B2 (en) 2017-06-27 2023-09-26 Cilag Gmbh International Surgical anvil arrangements
US11771419B2 (en) 2019-06-28 2023-10-03 Cilag Gmbh International Packaging for a replaceable component of a surgical stapling system
US11779420B2 (en) 2012-06-28 2023-10-10 Cilag Gmbh International Robotic surgical attachments having manually-actuated retraction assemblies
US11779330B2 (en) 2020-10-29 2023-10-10 Cilag Gmbh International Surgical instrument comprising a jaw alignment system
US11786243B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Firing members having flexible portions for adapting to a load during a surgical firing stroke
US11786239B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Surgical instrument articulation joint arrangements comprising multiple moving linkage features
US11793514B2 (en) 2021-02-26 2023-10-24 Cilag Gmbh International Staple cartridge comprising sensor array which may be embedded in cartridge body
US11793522B2 (en) 2015-09-30 2023-10-24 Cilag Gmbh International Staple cartridge assembly including a compressible adjunct
US11793516B2 (en) 2021-03-24 2023-10-24 Cilag Gmbh International Surgical staple cartridge comprising longitudinal support beam
US11793518B2 (en) 2006-01-31 2023-10-24 Cilag Gmbh International Powered surgical instruments with firing system lockout arrangements
US11793513B2 (en) 2017-06-20 2023-10-24 Cilag Gmbh International Systems and methods for controlling motor speed according to user input for a surgical instrument
US11793511B2 (en) 2005-11-09 2023-10-24 Cilag Gmbh International Surgical instruments
US11801051B2 (en) 2006-01-31 2023-10-31 Cilag Gmbh International Accessing data stored in a memory of a surgical instrument
US11806011B2 (en) 2021-03-22 2023-11-07 Cilag Gmbh International Stapling instrument comprising tissue compression systems
US11812958B2 (en) 2014-12-18 2023-11-14 Cilag Gmbh International Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors
US11812964B2 (en) 2021-02-26 2023-11-14 Cilag Gmbh International Staple cartridge comprising a power management circuit
US11826012B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Stapling instrument comprising a pulsed motor-driven firing rack
US11826048B2 (en) 2017-06-28 2023-11-28 Cilag Gmbh International Surgical instrument comprising selectively actuatable rotatable couplers
US11826042B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Surgical instrument comprising a firing drive including a selectable leverage mechanism
US11826132B2 (en) 2015-03-06 2023-11-28 Cilag Gmbh International Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US11832816B2 (en) 2021-03-24 2023-12-05 Cilag Gmbh International Surgical stapling assembly comprising nonplanar staples and planar staples
US11839352B2 (en) 2007-01-11 2023-12-12 Cilag Gmbh International Surgical stapling device with an end effector
US11844518B2 (en) 2020-10-29 2023-12-19 Cilag Gmbh International Method for operating a surgical instrument
US11844520B2 (en) 2019-12-19 2023-12-19 Cilag Gmbh International Staple cartridge comprising driver retention members
US11849941B2 (en) 2007-06-29 2023-12-26 Cilag Gmbh International Staple cartridge having staple cavities extending at a transverse angle relative to a longitudinal cartridge axis
US11849943B2 (en) 2020-12-02 2023-12-26 Cilag Gmbh International Surgical instrument with cartridge release mechanisms
US11849945B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Rotary-driven surgical stapling assembly comprising eccentrically driven firing member
US11853835B2 (en) 2019-06-28 2023-12-26 Cilag Gmbh International RFID identification systems for surgical instruments
US11849952B2 (en) 2010-09-30 2023-12-26 Cilag Gmbh International Staple cartridge comprising staples positioned within a compressible portion thereof
US11849944B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Drivers for fastener cartridge assemblies having rotary drive screws
US11857187B2 (en) 2010-09-30 2024-01-02 Cilag Gmbh International Tissue thickness compensator comprising controlled release and expansion
CN117416613A (zh) * 2022-07-18 2024-01-19 格雷斯海姆玻璃有限责任公司 医疗容器包装
CN117416612A (zh) * 2022-07-18 2024-01-19 格雷斯海姆玻璃有限责任公司 医疗容器包装
US11877745B2 (en) 2021-10-18 2024-01-23 Cilag Gmbh International Surgical stapling assembly having longitudinally-repeating staple leg clusters
US11883025B2 (en) 2010-09-30 2024-01-30 Cilag Gmbh International Tissue thickness compensator comprising a plurality of layers
US11883026B2 (en) 2014-04-16 2024-01-30 Cilag Gmbh International Fastener cartridge assemblies and staple retainer cover arrangements
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US11883020B2 (en) 2006-01-31 2024-01-30 Cilag Gmbh International Surgical instrument having a feedback system
US11890012B2 (en) 2004-07-28 2024-02-06 Cilag Gmbh International Staple cartridge comprising cartridge body and attached support
US11890010B2 (en) 2020-12-02 2024-02-06 Cllag GmbH International Dual-sided reinforced reload for surgical instruments
US11890005B2 (en) 2017-06-29 2024-02-06 Cilag Gmbh International Methods for closed loop velocity control for robotic surgical instrument
US11896217B2 (en) 2020-10-29 2024-02-13 Cilag Gmbh International Surgical instrument comprising an articulation lock
US11896218B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Method of using a powered stapling device
US11896222B2 (en) 2017-12-15 2024-02-13 Cilag Gmbh International Methods of operating surgical end effectors
US11896219B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Mating features between drivers and underside of a cartridge deck
US11903581B2 (en) 2019-04-30 2024-02-20 Cilag Gmbh International Methods for stapling tissue using a surgical instrument
US11903582B2 (en) 2021-03-24 2024-02-20 Cilag Gmbh International Leveraging surfaces for cartridge installation
US11911032B2 (en) 2019-12-19 2024-02-27 Cilag Gmbh International Staple cartridge comprising a seating cam
US11918220B2 (en) 2012-03-28 2024-03-05 Cilag Gmbh International Tissue thickness compensator comprising tissue ingrowth features
US11918212B2 (en) 2015-03-31 2024-03-05 Cilag Gmbh International Surgical instrument with selectively disengageable drive systems
US11925349B2 (en) 2021-02-26 2024-03-12 Cilag Gmbh International Adjustment to transfer parameters to improve available power
USD1018577S1 (en) 2017-06-28 2024-03-19 Cilag Gmbh International Display screen or portion thereof with a graphical user interface for a surgical instrument
US11931034B2 (en) 2016-12-21 2024-03-19 Cilag Gmbh International Surgical stapling instruments with smart staple cartridges
US11931033B2 (en) 2019-12-19 2024-03-19 Cilag Gmbh International Staple cartridge comprising a latch lockout
US11931025B2 (en) 2020-10-29 2024-03-19 Cilag Gmbh International Surgical instrument comprising a releasable closure drive lock
US11937816B2 (en) 2021-10-28 2024-03-26 Cilag Gmbh International Electrical lead arrangements for surgical instruments
US11944336B2 (en) 2021-03-24 2024-04-02 Cilag Gmbh International Joint arrangements for multi-planar alignment and support of operational drive shafts in articulatable surgical instruments
US11944338B2 (en) 2015-03-06 2024-04-02 Cilag Gmbh International Multiple level thresholds to modify operation of powered surgical instruments
US11944296B2 (en) 2020-12-02 2024-04-02 Cilag Gmbh International Powered surgical instruments with external connectors
US11944300B2 (en) 2017-08-03 2024-04-02 Cilag Gmbh International Method for operating a surgical system bailout
US11950777B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Staple cartridge comprising an information access control system
US11950779B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Method of powering and communicating with a staple cartridge
US11957337B2 (en) 2021-10-18 2024-04-16 Cilag Gmbh International Surgical stapling assembly with offset ramped drive surfaces
US11974742B2 (en) 2017-08-03 2024-05-07 Cilag Gmbh International Surgical system comprising an articulation bailout
US11980366B2 (en) 2006-10-03 2024-05-14 Cilag Gmbh International Surgical instrument
US11980362B2 (en) 2021-02-26 2024-05-14 Cilag Gmbh International Surgical instrument system comprising a power transfer coil
US11980363B2 (en) 2021-10-18 2024-05-14 Cilag Gmbh International Row-to-row staple array variations
US11986183B2 (en) 2008-02-14 2024-05-21 Cilag Gmbh International Surgical cutting and fastening instrument comprising a plurality of sensors to measure an electrical parameter
US11998199B2 (en) 2017-09-29 2024-06-04 Cllag GmbH International System and methods for controlling a display of a surgical instrument
US11998206B2 (en) 2008-02-14 2024-06-04 Cilag Gmbh International Detachable motor powered surgical instrument
US11998200B2 (en) 2007-06-22 2024-06-04 Cilag Gmbh International Surgical stapling instrument with an articulatable end effector
US11998198B2 (en) 2004-07-28 2024-06-04 Cilag Gmbh International Surgical stapling instrument incorporating a two-piece E-beam firing mechanism
US12004740B2 (en) 2019-06-28 2024-06-11 Cilag Gmbh International Surgical stapling system having an information decryption protocol
US12004745B2 (en) 2016-12-21 2024-06-11 Cilag Gmbh International Surgical instrument system comprising an end effector lockout and a firing assembly lockout
US12016564B2 (en) 2014-09-26 2024-06-25 Cilag Gmbh International Circular fastener cartridges for applying radially expandable fastener lines
US12035913B2 (en) 2019-12-19 2024-07-16 Cilag Gmbh International Staple cartridge comprising a deployable knife
US12053175B2 (en) 2020-10-29 2024-08-06 Cilag Gmbh International Surgical instrument comprising a stowed closure actuator stop
US12076017B2 (en) 2014-09-18 2024-09-03 Cilag Gmbh International Surgical instrument including a deployable knife
US12089841B2 (en) 2021-10-28 2024-09-17 Cilag CmbH International Staple cartridge identification systems
US12102323B2 (en) 2021-03-24 2024-10-01 Cilag Gmbh International Rotary-driven surgical stapling assembly comprising a floatable component
US12108951B2 (en) 2021-02-26 2024-10-08 Cilag Gmbh International Staple cartridge comprising a sensing array and a temperature control system
US12171507B2 (en) 2016-08-16 2024-12-24 Cilag Gmbh International Surgical tool with manual control of end effector jaws
US12207835B2 (en) 2009-12-24 2025-01-28 Cilag Gmbh International Motor-driven surgical cutting instrument with electric actuator directional control assembly
US12213666B2 (en) 2010-09-30 2025-02-04 Cilag Gmbh International Tissue thickness compensator comprising layers
US12232723B2 (en) 2014-03-26 2025-02-25 Cilag Gmbh International Systems and methods for controlling a segmented circuit
US12239317B2 (en) 2021-10-18 2025-03-04 Cilag Gmbh International Anvil comprising an arrangement of forming pockets proximal to tissue stop
US12245764B2 (en) 2016-12-21 2025-03-11 Cilag Gmbh International Shaft assembly comprising a lockout
US12262888B2 (en) 2018-08-20 2025-04-01 Cilag Gmbh International Surgical instruments with progressive jaw closure arrangements
US12274442B2 (en) 2016-12-21 2025-04-15 Cilag Gmbh International Surgical staple cartridge alignment features
US12286270B2 (en) 2021-05-18 2025-04-29 Gerresheimer Glas Gmbh Transporting packaging units
US12285166B2 (en) 2014-03-26 2025-04-29 Cilag Gmbh International Feedback algorithms for manual bailout systems for surgical instruments
US12319466B2 (en) 2021-05-18 2025-06-03 Gerresheimer Glas Gmbh Transporting packaging units
US12324580B2 (en) 2021-02-26 2025-06-10 Cilag Gmbh International Method of powering and communicating with a staple cartridge
US12336705B2 (en) 2017-12-21 2025-06-24 Cilag Gmbh International Continuous use self-propelled stapling instrument
US12383267B2 (en) 2012-06-28 2025-08-12 Cilag Gmbh International Robotically powered surgical device with manually-actuatable reversing system
US12432790B2 (en) 2021-10-28 2025-09-30 Cilag Gmbh International Method and device for transmitting UART communications over a security short range wireless communication
RU2847337C1 (ru) * 2020-12-17 2025-10-03 Цобеле Холдинг Спа Контейнер для рассеивания летучих веществ
US12440208B2 (en) 2015-03-06 2025-10-14 Cilag Gmbh International Powered surgical instrument
US12471982B2 (en) 2020-12-02 2025-11-18 Cilag Gmbh International Method for tissue treatment by surgical instrument

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617178A (en) * 1984-11-05 1986-10-14 Nichols Robert L Medical instrument sterilization container
US20030118491A1 (en) * 1998-08-26 2003-06-26 Frieze Marcia A. Filtered gas plasma sterilization container with improved circulation
US6889839B1 (en) * 2002-05-07 2005-05-10 Perfecseal, Inc. Suspension package
US20050194387A1 (en) * 2004-03-08 2005-09-08 Banks Percival C. Protected seal for a filtered vent in a sterilization container
US20050238530A1 (en) * 2001-11-16 2005-10-27 Case Medical Inc. Rigid reusable sterilization container with thermostatic valve
WO2006063050A1 (fr) * 2004-12-08 2006-06-15 Perfecseal, Inc. Emballage sterilisable avec un fort barrage a l'oxygene
US20100154353A1 (en) * 2008-12-24 2010-06-24 Cesa Joseph A Single Use Sterilization Container
US20100158753A1 (en) * 2008-12-24 2010-06-24 Steven Scott Friderich Sterilization container with peel top
US20110214398A1 (en) * 2010-03-05 2011-09-08 Edwards Lifesciences Corporation Dry Prosthetic Heart Valve Packaging System
US20120152289A1 (en) * 2010-12-21 2012-06-21 Tara Denise Smith Sterilization Container With Disposable Liner
US20120158128A1 (en) * 2010-12-16 2012-06-21 Edwards Lifesciences Corporation Prosthetic heart valve delivery systems and packaging
US20120195792A1 (en) * 2011-02-02 2012-08-02 Symmetry Medical Manufacturing, Inc. Medical Instrument Sterilization System and Method
US20130277261A1 (en) * 2012-04-23 2013-10-24 Perfecseal, Inc. Packaging for a Size Varying Series of Femoral Components for Artificial Knee Joints

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4617178A (en) * 1984-11-05 1986-10-14 Nichols Robert L Medical instrument sterilization container
US20030118491A1 (en) * 1998-08-26 2003-06-26 Frieze Marcia A. Filtered gas plasma sterilization container with improved circulation
US20050238530A1 (en) * 2001-11-16 2005-10-27 Case Medical Inc. Rigid reusable sterilization container with thermostatic valve
US6889839B1 (en) * 2002-05-07 2005-05-10 Perfecseal, Inc. Suspension package
US20050194387A1 (en) * 2004-03-08 2005-09-08 Banks Percival C. Protected seal for a filtered vent in a sterilization container
WO2006063050A1 (fr) * 2004-12-08 2006-06-15 Perfecseal, Inc. Emballage sterilisable avec un fort barrage a l'oxygene
US20100154353A1 (en) * 2008-12-24 2010-06-24 Cesa Joseph A Single Use Sterilization Container
US20100158753A1 (en) * 2008-12-24 2010-06-24 Steven Scott Friderich Sterilization container with peel top
US20110214398A1 (en) * 2010-03-05 2011-09-08 Edwards Lifesciences Corporation Dry Prosthetic Heart Valve Packaging System
US20120158128A1 (en) * 2010-12-16 2012-06-21 Edwards Lifesciences Corporation Prosthetic heart valve delivery systems and packaging
US20120152289A1 (en) * 2010-12-21 2012-06-21 Tara Denise Smith Sterilization Container With Disposable Liner
US20120195792A1 (en) * 2011-02-02 2012-08-02 Symmetry Medical Manufacturing, Inc. Medical Instrument Sterilization System and Method
US20130277261A1 (en) * 2012-04-23 2013-10-24 Perfecseal, Inc. Packaging for a Size Varying Series of Femoral Components for Artificial Knee Joints

Cited By (615)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11812960B2 (en) 2004-07-28 2023-11-14 Cilag Gmbh International Method of segmenting the operation of a surgical stapling instrument
US11896225B2 (en) 2004-07-28 2024-02-13 Cilag Gmbh International Staple cartridge comprising a pan
US11116502B2 (en) 2004-07-28 2021-09-14 Cilag Gmbh International Surgical stapling instrument incorporating a two-piece firing mechanism
US11684365B2 (en) 2004-07-28 2023-06-27 Cilag Gmbh International Replaceable staple cartridges for surgical instruments
US12011165B2 (en) 2004-07-28 2024-06-18 Cilag Gmbh International Surgical stapling instrument comprising replaceable staple cartridge
US11135352B2 (en) 2004-07-28 2021-10-05 Cilag Gmbh International End effector including a gradually releasable medical adjunct
US12029423B2 (en) 2004-07-28 2024-07-09 Cilag Gmbh International Surgical stapling instrument comprising a staple cartridge
US11963679B2 (en) 2004-07-28 2024-04-23 Cilag Gmbh International Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism
US11083456B2 (en) 2004-07-28 2021-08-10 Cilag Gmbh International Articulating surgical instrument incorporating a two-piece firing mechanism
US11890012B2 (en) 2004-07-28 2024-02-06 Cilag Gmbh International Staple cartridge comprising cartridge body and attached support
US11998198B2 (en) 2004-07-28 2024-06-04 Cilag Gmbh International Surgical stapling instrument incorporating a two-piece E-beam firing mechanism
US11882987B2 (en) 2004-07-28 2024-01-30 Cilag Gmbh International Articulating surgical stapling instrument incorporating a two-piece E-beam firing mechanism
US11484312B2 (en) 2005-08-31 2022-11-01 Cilag Gmbh International Staple cartridge comprising a staple driver arrangement
US11576673B2 (en) 2005-08-31 2023-02-14 Cilag Gmbh International Stapling assembly for forming staples to different heights
US11771425B2 (en) 2005-08-31 2023-10-03 Cilag Gmbh International Stapling assembly for forming staples to different formed heights
US11839375B2 (en) 2005-08-31 2023-12-12 Cilag Gmbh International Fastener cartridge assembly comprising an anvil and different staple heights
US11399828B2 (en) 2005-08-31 2022-08-02 Cilag Gmbh International Fastener cartridge assembly comprising a fixed anvil and different staple heights
US11179153B2 (en) 2005-08-31 2021-11-23 Cilag Gmbh International Staple cartridges for forming staples having differing formed staple heights
US11134947B2 (en) 2005-08-31 2021-10-05 Cilag Gmbh International Fastener cartridge assembly comprising a camming sled with variable cam arrangements
US11730474B2 (en) 2005-08-31 2023-08-22 Cilag Gmbh International Fastener cartridge assembly comprising a movable cartridge and a staple driver arrangement
US11793512B2 (en) 2005-08-31 2023-10-24 Cilag Gmbh International Staple cartridges for forming staples having differing formed staple heights
US11172927B2 (en) 2005-08-31 2021-11-16 Cilag Gmbh International Staple cartridges for forming staples having differing formed staple heights
US11484311B2 (en) 2005-08-31 2022-11-01 Cilag Gmbh International Staple cartridge comprising a staple driver arrangement
US11246590B2 (en) 2005-08-31 2022-02-15 Cilag Gmbh International Staple cartridge including staple drivers having different unfired heights
US11090045B2 (en) 2005-08-31 2021-08-17 Cilag Gmbh International Staple cartridges for forming staples having differing formed staple heights
US11272928B2 (en) 2005-08-31 2022-03-15 Cilag GmbH Intemational Staple cartridges for forming staples having differing formed staple heights
US11793511B2 (en) 2005-11-09 2023-10-24 Cilag Gmbh International Surgical instruments
US11103269B2 (en) 2006-01-31 2021-08-31 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11890029B2 (en) 2006-01-31 2024-02-06 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument
US11166717B2 (en) 2006-01-31 2021-11-09 Cilag Gmbh International Surgical instrument with firing lockout
US11660110B2 (en) 2006-01-31 2023-05-30 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11648024B2 (en) 2006-01-31 2023-05-16 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with position feedback
US11364046B2 (en) 2006-01-31 2022-06-21 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11246616B2 (en) 2006-01-31 2022-02-15 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11278279B2 (en) 2006-01-31 2022-03-22 Cilag Gmbh International Surgical instrument assembly
US11350916B2 (en) 2006-01-31 2022-06-07 Cilag Gmbh International Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
US11612393B2 (en) 2006-01-31 2023-03-28 Cilag Gmbh International Robotically-controlled end effector
US11793518B2 (en) 2006-01-31 2023-10-24 Cilag Gmbh International Powered surgical instruments with firing system lockout arrangements
US12433584B2 (en) 2006-01-31 2025-10-07 Cilag Gmbh International Robotically-controlled end effector
US11224427B2 (en) 2006-01-31 2022-01-18 Cilag Gmbh International Surgical stapling system including a console and retraction assembly
US11801051B2 (en) 2006-01-31 2023-10-31 Cilag Gmbh International Accessing data stored in a memory of a surgical instrument
US12161329B2 (en) 2006-01-31 2024-12-10 Cilag Gmbh International Surgical systems comprising a control circuit including a timer
US11944299B2 (en) 2006-01-31 2024-04-02 Cilag Gmbh International Surgical instrument having force feedback capabilities
US11224454B2 (en) 2006-01-31 2022-01-18 Cilag Gmbh International Motor-driven surgical cutting and fastening instrument with tactile position feedback
US11648008B2 (en) 2006-01-31 2023-05-16 Cilag Gmbh International Surgical instrument having force feedback capabilities
US11883020B2 (en) 2006-01-31 2024-01-30 Cilag Gmbh International Surgical instrument having a feedback system
US11890008B2 (en) 2006-01-31 2024-02-06 Cilag Gmbh International Surgical instrument with firing lockout
US11051813B2 (en) 2006-01-31 2021-07-06 Cilag Gmbh International Powered surgical instruments with firing system lockout arrangements
US12171508B2 (en) 2006-03-23 2024-12-24 Cilag Gmbh International Robotically-controlled surgical instrument with selectively articulatable end effector
US11272938B2 (en) 2006-06-27 2022-03-15 Cilag Gmbh International Surgical instrument including dedicated firing and retraction assemblies
US11571231B2 (en) 2006-09-29 2023-02-07 Cilag Gmbh International Staple cartridge having a driver for driving multiple staples
US11622785B2 (en) 2006-09-29 2023-04-11 Cilag Gmbh International Surgical staples having attached drivers and stapling instruments for deploying the same
US11980366B2 (en) 2006-10-03 2024-05-14 Cilag Gmbh International Surgical instrument
US11877748B2 (en) 2006-10-03 2024-01-23 Cilag Gmbh International Robotically-driven surgical instrument with E-beam driver
US12178434B2 (en) 2006-10-03 2024-12-31 Cilag Gmbh International Surgical stapling system including control circuit to monitor clamping pressure
US11382626B2 (en) 2006-10-03 2022-07-12 Cilag Gmbh International Surgical system including a knife bar supported for rotational and axial travel
US12004743B2 (en) 2007-01-10 2024-06-11 Cilag Gmbh International Staple cartridge comprising a sloped wall
US11812961B2 (en) 2007-01-10 2023-11-14 Cilag Gmbh International Surgical instrument including a motor control system
US11350929B2 (en) 2007-01-10 2022-06-07 Cilag Gmbh International Surgical instrument with wireless communication between control unit and sensor transponders
US11918211B2 (en) 2007-01-10 2024-03-05 Cilag Gmbh International Surgical stapling instrument for use with a robotic system
US11166720B2 (en) 2007-01-10 2021-11-09 Cilag Gmbh International Surgical instrument including a control module for assessing an end effector
US12082806B2 (en) 2007-01-10 2024-09-10 Cilag Gmbh International Surgical instrument with wireless communication between control unit and sensor transponders
US11291441B2 (en) 2007-01-10 2022-04-05 Cilag Gmbh International Surgical instrument with wireless communication between control unit and remote sensor
US11931032B2 (en) 2007-01-10 2024-03-19 Cilag Gmbh International Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor
US11849947B2 (en) 2007-01-10 2023-12-26 Cilag Gmbh International Surgical system including a control circuit and a passively-powered transponder
US11771426B2 (en) 2007-01-10 2023-10-03 Cilag Gmbh International Surgical instrument with wireless communication
US11134943B2 (en) 2007-01-10 2021-10-05 Cilag Gmbh International Powered surgical instrument including a control unit and sensor
US11666332B2 (en) 2007-01-10 2023-06-06 Cilag Gmbh International Surgical instrument comprising a control circuit configured to adjust the operation of a motor
US11937814B2 (en) 2007-01-10 2024-03-26 Cilag Gmbh International Surgical instrument for use with a robotic system
US11844521B2 (en) 2007-01-10 2023-12-19 Cilag Gmbh International Surgical instrument for use with a robotic system
US11839352B2 (en) 2007-01-11 2023-12-12 Cilag Gmbh International Surgical stapling device with an end effector
US11337693B2 (en) 2007-03-15 2022-05-24 Cilag Gmbh International Surgical stapling instrument having a releasable buttress material
US11134938B2 (en) 2007-06-04 2021-10-05 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11648006B2 (en) 2007-06-04 2023-05-16 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11564682B2 (en) 2007-06-04 2023-01-31 Cilag Gmbh International Surgical stapler device
US11857181B2 (en) 2007-06-04 2024-01-02 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11559302B2 (en) 2007-06-04 2023-01-24 Cilag Gmbh International Surgical instrument including a firing member movable at different speeds
US12035906B2 (en) 2007-06-04 2024-07-16 Cilag Gmbh International Surgical instrument including a handle system for advancing a cutting member
US11911028B2 (en) 2007-06-04 2024-02-27 Cilag Gmbh International Surgical instruments for use with a robotic surgical system
US11672531B2 (en) 2007-06-04 2023-06-13 Cilag Gmbh International Rotary drive systems for surgical instruments
US11147549B2 (en) 2007-06-04 2021-10-19 Cilag Gmbh International Stapling instrument including a firing system and a closure system
US12023024B2 (en) 2007-06-04 2024-07-02 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11992208B2 (en) 2007-06-04 2024-05-28 Cilag Gmbh International Rotary drive systems for surgical instruments
US11998200B2 (en) 2007-06-22 2024-06-04 Cilag Gmbh International Surgical stapling instrument with an articulatable end effector
US11925346B2 (en) 2007-06-29 2024-03-12 Cilag Gmbh International Surgical staple cartridge including tissue supporting surfaces
US11849941B2 (en) 2007-06-29 2023-12-26 Cilag Gmbh International Staple cartridge having staple cavities extending at a transverse angle relative to a longitudinal cartridge axis
US12023025B2 (en) 2007-06-29 2024-07-02 Cilag Gmbh International Surgical stapling instrument having a releasable buttress material
US11986183B2 (en) 2008-02-14 2024-05-21 Cilag Gmbh International Surgical cutting and fastening instrument comprising a plurality of sensors to measure an electrical parameter
US11484307B2 (en) 2008-02-14 2022-11-01 Cilag Gmbh International Loading unit coupleable to a surgical stapling system
US11801047B2 (en) 2008-02-14 2023-10-31 Cilag Gmbh International Surgical stapling system comprising a control circuit configured to selectively monitor tissue impedance and adjust control of a motor
US11717285B2 (en) 2008-02-14 2023-08-08 Cilag Gmbh International Surgical cutting and fastening instrument having RF electrodes
US11571212B2 (en) 2008-02-14 2023-02-07 Cilag Gmbh International Surgical stapling system including an impedance sensor
US11464514B2 (en) 2008-02-14 2022-10-11 Cilag Gmbh International Motorized surgical stapling system including a sensing array
US11638583B2 (en) 2008-02-14 2023-05-02 Cilag Gmbh International Motorized surgical system having a plurality of power sources
US11612395B2 (en) 2008-02-14 2023-03-28 Cilag Gmbh International Surgical system including a control system having an RFID tag reader
US11446034B2 (en) 2008-02-14 2022-09-20 Cilag Gmbh International Surgical stapling assembly comprising first and second actuation systems configured to perform different functions
US11998206B2 (en) 2008-02-14 2024-06-04 Cilag Gmbh International Detachable motor powered surgical instrument
US12213671B2 (en) 2008-02-14 2025-02-04 Cilag Gmbh International Motorized system having a plurality of power sources
US11998194B2 (en) 2008-02-15 2024-06-04 Cilag Gmbh International Surgical stapling assembly comprising an adjunct applicator
US11154297B2 (en) 2008-02-15 2021-10-26 Cilag Gmbh International Layer arrangements for surgical staple cartridges
US11871923B2 (en) 2008-09-23 2024-01-16 Cilag Gmbh International Motorized surgical instrument
US11617575B2 (en) 2008-09-23 2023-04-04 Cilag Gmbh International Motor-driven surgical cutting instrument
US11648005B2 (en) 2008-09-23 2023-05-16 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US11684361B2 (en) 2008-09-23 2023-06-27 Cilag Gmbh International Motor-driven surgical cutting instrument
US11045189B2 (en) 2008-09-23 2021-06-29 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US11103241B2 (en) 2008-09-23 2021-08-31 Cilag Gmbh International Motor-driven surgical cutting instrument
US11617576B2 (en) 2008-09-23 2023-04-04 Cilag Gmbh International Motor-driven surgical cutting instrument
US11406380B2 (en) 2008-09-23 2022-08-09 Cilag Gmbh International Motorized surgical instrument
US11517304B2 (en) 2008-09-23 2022-12-06 Cilag Gmbh International Motor-driven surgical cutting instrument
US11812954B2 (en) 2008-09-23 2023-11-14 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US12029415B2 (en) 2008-09-23 2024-07-09 Cilag Gmbh International Motor-driven surgical cutting instrument
US11730477B2 (en) 2008-10-10 2023-08-22 Cilag Gmbh International Powered surgical system with manually retractable firing system
US11793521B2 (en) 2008-10-10 2023-10-24 Cilag Gmbh International Powered surgical cutting and stapling apparatus with manually retractable firing system
US11583279B2 (en) 2008-10-10 2023-02-21 Cilag Gmbh International Powered surgical cutting and stapling apparatus with manually retractable firing system
US11129615B2 (en) 2009-02-05 2021-09-28 Cilag Gmbh International Surgical stapling system
US11291449B2 (en) 2009-12-24 2022-04-05 Cilag Gmbh International Surgical cutting instrument that analyzes tissue thickness
US12207835B2 (en) 2009-12-24 2025-01-28 Cilag Gmbh International Motor-driven surgical cutting instrument with electric actuator directional control assembly
US11478247B2 (en) 2010-07-30 2022-10-25 Cilag Gmbh International Tissue acquisition arrangements and methods for surgical stapling devices
US11925354B2 (en) 2010-09-30 2024-03-12 Cilag Gmbh International Staple cartridge comprising staples positioned within a compressible portion thereof
US12178432B2 (en) 2010-09-30 2024-12-31 Cilag Gmbh International Tissue thickness compensator comprising laterally offset layers
US11406377B2 (en) 2010-09-30 2022-08-09 Cilag Gmbh International Adhesive film laminate
US11395651B2 (en) 2010-09-30 2022-07-26 Cilag Gmbh International Adhesive film laminate
US11812965B2 (en) 2010-09-30 2023-11-14 Cilag Gmbh International Layer of material for a surgical end effector
US11583277B2 (en) 2010-09-30 2023-02-21 Cilag Gmbh International Layer of material for a surgical end effector
US11298125B2 (en) 2010-09-30 2022-04-12 Cilag Gmbh International Tissue stapler having a thickness compensator
US11957795B2 (en) 2010-09-30 2024-04-16 Cilag Gmbh International Tissue thickness compensator configured to redistribute compressive forces
US11857187B2 (en) 2010-09-30 2024-01-02 Cilag Gmbh International Tissue thickness compensator comprising controlled release and expansion
US11571215B2 (en) 2010-09-30 2023-02-07 Cilag Gmbh International Layer of material for a surgical end effector
US11911027B2 (en) 2010-09-30 2024-02-27 Cilag Gmbh International Adhesive film laminate
US11849952B2 (en) 2010-09-30 2023-12-26 Cilag Gmbh International Staple cartridge comprising staples positioned within a compressible portion thereof
US11944292B2 (en) 2010-09-30 2024-04-02 Cilag Gmbh International Anvil layer attached to a proximal end of an end effector
US11850310B2 (en) 2010-09-30 2023-12-26 Cilag Gmbh International Staple cartridge including an adjunct
US11559496B2 (en) 2010-09-30 2023-01-24 Cilag Gmbh International Tissue thickness compensator configured to redistribute compressive forces
US12213666B2 (en) 2010-09-30 2025-02-04 Cilag Gmbh International Tissue thickness compensator comprising layers
US11737754B2 (en) 2010-09-30 2023-08-29 Cilag Gmbh International Surgical stapler with floating anvil
US11684360B2 (en) 2010-09-30 2023-06-27 Cilag Gmbh International Staple cartridge comprising a variable thickness compressible portion
US11672536B2 (en) 2010-09-30 2023-06-13 Cilag Gmbh International Layer of material for a surgical end effector
US11883025B2 (en) 2010-09-30 2024-01-30 Cilag Gmbh International Tissue thickness compensator comprising a plurality of layers
US11154296B2 (en) 2010-09-30 2021-10-26 Cilag Gmbh International Anvil layer attached to a proximal end of an end effector
US11602340B2 (en) 2010-09-30 2023-03-14 Cilag Gmbh International Adhesive film laminate
US12453557B2 (en) 2010-09-30 2025-10-28 Cilag Gmbh International Layer of material for a surgical end effector
US11529142B2 (en) 2010-10-01 2022-12-20 Cilag Gmbh International Surgical instrument having a power control circuit
US12440213B2 (en) 2010-10-01 2025-10-14 Cilag Gmbh International Surgical instrument having a power control circuit
US11504116B2 (en) 2011-04-29 2022-11-22 Cilag Gmbh International Layer of material for a surgical end effector
US12256930B2 (en) 2011-05-27 2025-03-25 Cilag Gmbh International Robotically-driven surgical instrument with E-beam driver
US11207064B2 (en) 2011-05-27 2021-12-28 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US12290261B2 (en) 2011-05-27 2025-05-06 Cilag Gmbh International Robotically-driven surgical instrument with E-beam driver
US11129616B2 (en) 2011-05-27 2021-09-28 Cilag Gmbh International Surgical stapling system
US11918208B2 (en) 2011-05-27 2024-03-05 Cilag Gmbh International Robotically-controlled shaft based rotary drive systems for surgical instruments
US11612394B2 (en) 2011-05-27 2023-03-28 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US11266410B2 (en) 2011-05-27 2022-03-08 Cilag Gmbh International Surgical device for use with a robotic system
US11974747B2 (en) 2011-05-27 2024-05-07 Cilag Gmbh International Surgical stapling instruments with rotatable staple deployment arrangements
US12239316B2 (en) 2011-05-27 2025-03-04 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US12059154B2 (en) 2011-05-27 2024-08-13 Cilag Gmbh International Surgical instrument with detachable motor control unit
US11583278B2 (en) 2011-05-27 2023-02-21 Cilag Gmbh International Surgical stapling system having multi-direction articulation
US11439470B2 (en) 2011-05-27 2022-09-13 Cilag Gmbh International Robotically-controlled surgical instrument with selectively articulatable end effector
US11793509B2 (en) 2012-03-28 2023-10-24 Cilag Gmbh International Staple cartridge including an implantable layer
US11406378B2 (en) 2012-03-28 2022-08-09 Cilag Gmbh International Staple cartridge comprising a compressible tissue thickness compensator
US12121234B2 (en) 2012-03-28 2024-10-22 Cilag Gmbh International Staple cartridge assembly comprising a compensator
US11918220B2 (en) 2012-03-28 2024-03-05 Cilag Gmbh International Tissue thickness compensator comprising tissue ingrowth features
US11707273B2 (en) 2012-06-15 2023-07-25 Cilag Gmbh International Articulatable surgical instrument comprising a firing drive
US11278284B2 (en) 2012-06-28 2022-03-22 Cilag Gmbh International Rotary drive arrangements for surgical instruments
US11202631B2 (en) 2012-06-28 2021-12-21 Cilag Gmbh International Stapling assembly comprising a firing lockout
US11602346B2 (en) 2012-06-28 2023-03-14 Cilag Gmbh International Robotically powered surgical device with manually-actuatable reversing system
US11622766B2 (en) 2012-06-28 2023-04-11 Cilag Gmbh International Empty clip cartridge lockout
US12343013B2 (en) 2012-06-28 2025-07-01 Cilag Gmbh International Interconnected joint segments forming drive tube for stapling assembly
US12369911B2 (en) 2012-06-28 2025-07-29 Cilag Gmbh International Firing system lockout arrangements for surgical instruments
US11857189B2 (en) 2012-06-28 2024-01-02 Cilag Gmbh International Surgical instrument including first and second articulation joints
US11241230B2 (en) 2012-06-28 2022-02-08 Cilag Gmbh International Clip applier tool for use with a robotic surgical system
US12383267B2 (en) 2012-06-28 2025-08-12 Cilag Gmbh International Robotically powered surgical device with manually-actuatable reversing system
US11540829B2 (en) 2012-06-28 2023-01-03 Cilag Gmbh International Surgical instrument system including replaceable end effectors
US11534162B2 (en) 2012-06-28 2022-12-27 Cilag GmbH Inlernational Robotically powered surgical device with manually-actuatable reversing system
US11464513B2 (en) 2012-06-28 2022-10-11 Cilag Gmbh International Surgical instrument system including replaceable end effectors
US11141156B2 (en) 2012-06-28 2021-10-12 Cilag Gmbh International Surgical stapling assembly comprising flexible output shaft
US11083457B2 (en) 2012-06-28 2021-08-10 Cilag Gmbh International Surgical instrument system including replaceable end effectors
US11197671B2 (en) 2012-06-28 2021-12-14 Cilag Gmbh International Stapling assembly comprising a lockout
US11510671B2 (en) 2012-06-28 2022-11-29 Cilag Gmbh International Firing system lockout arrangements for surgical instruments
US11918213B2 (en) 2012-06-28 2024-03-05 Cilag Gmbh International Surgical stapler including couplers for attaching a shaft to an end effector
US11779420B2 (en) 2012-06-28 2023-10-10 Cilag Gmbh International Robotic surgical attachments having manually-actuated retraction assemblies
US11141155B2 (en) 2012-06-28 2021-10-12 Cilag Gmbh International Drive system for surgical tool
US11154299B2 (en) 2012-06-28 2021-10-26 Cilag Gmbh International Stapling assembly comprising a firing lockout
US11806013B2 (en) 2012-06-28 2023-11-07 Cilag Gmbh International Firing system arrangements for surgical instruments
US11373755B2 (en) 2012-08-23 2022-06-28 Cilag Gmbh International Surgical device drive system including a ratchet mechanism
US11957345B2 (en) 2013-03-01 2024-04-16 Cilag Gmbh International Articulatable surgical instruments with conductive pathways for signal communication
US12433627B2 (en) 2013-03-01 2025-10-07 Cilag Gmbh International Surgical instrument soft stop
US11529138B2 (en) 2013-03-01 2022-12-20 Cilag Gmbh International Powered surgical instrument including a rotary drive screw
US11246618B2 (en) 2013-03-01 2022-02-15 Cilag Gmbh International Surgical instrument soft stop
US11992214B2 (en) 2013-03-14 2024-05-28 Cilag Gmbh International Control systems for surgical instruments
US11266406B2 (en) 2013-03-14 2022-03-08 Cilag Gmbh International Control systems for surgical instruments
US11395652B2 (en) 2013-04-16 2022-07-26 Cilag Gmbh International Powered surgical stapler
US11622763B2 (en) 2013-04-16 2023-04-11 Cilag Gmbh International Stapling assembly comprising a shiftable drive
US11564679B2 (en) 2013-04-16 2023-01-31 Cilag Gmbh International Powered surgical stapler
US11633183B2 (en) 2013-04-16 2023-04-25 Cilag International GmbH Stapling assembly comprising a retraction drive
US11406381B2 (en) 2013-04-16 2022-08-09 Cilag Gmbh International Powered surgical stapler
US12178429B2 (en) 2013-04-16 2024-12-31 Cilag Gmbh International Surgical instruments having modular end effector selectively coupleable to housing assembly
US11638581B2 (en) 2013-04-16 2023-05-02 Cilag Gmbh International Powered surgical stapler
US12161320B2 (en) 2013-04-16 2024-12-10 Cilag Gmbh International Powered surgical stapler
US11690615B2 (en) 2013-04-16 2023-07-04 Cilag Gmbh International Surgical system including an electric motor and a surgical instrument
US11133106B2 (en) 2013-08-23 2021-09-28 Cilag Gmbh International Surgical instrument assembly comprising a retraction assembly
US11389160B2 (en) 2013-08-23 2022-07-19 Cilag Gmbh International Surgical system comprising a display
US11701110B2 (en) 2013-08-23 2023-07-18 Cilag Gmbh International Surgical instrument including a drive assembly movable in a non-motorized mode of operation
US12053176B2 (en) 2013-08-23 2024-08-06 Cilag Gmbh International End effector detention systems for surgical instruments
US11918209B2 (en) 2013-08-23 2024-03-05 Cilag Gmbh International Torque optimization for surgical instruments
US11504119B2 (en) 2013-08-23 2022-11-22 Cilag Gmbh International Surgical instrument including an electronic firing lockout
US11376001B2 (en) 2013-08-23 2022-07-05 Cilag Gmbh International Surgical stapling device with rotary multi-turn retraction mechanism
US11109858B2 (en) 2013-08-23 2021-09-07 Cilag Gmbh International Surgical instrument including a display which displays the position of a firing element
US11497488B2 (en) 2014-03-26 2022-11-15 Cilag Gmbh International Systems and methods for controlling a segmented circuit
US12285166B2 (en) 2014-03-26 2025-04-29 Cilag Gmbh International Feedback algorithms for manual bailout systems for surgical instruments
US12232723B2 (en) 2014-03-26 2025-02-25 Cilag Gmbh International Systems and methods for controlling a segmented circuit
US12023022B2 (en) 2014-03-26 2024-07-02 Cilag Gmbh International Systems and methods for controlling a segmented circuit
US12023023B2 (en) 2014-03-26 2024-07-02 Cilag Gmbh International Interface systems for use with surgical instruments
US11259799B2 (en) 2014-03-26 2022-03-01 Cilag Gmbh International Interface systems for use with surgical instruments
US11963678B2 (en) 2014-04-16 2024-04-23 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US12285171B2 (en) 2014-04-16 2025-04-29 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US11298134B2 (en) 2014-04-16 2022-04-12 Cilag Gmbh International Fastener cartridge comprising non-uniform fasteners
US12465363B2 (en) 2014-04-16 2025-11-11 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US12324585B2 (en) 2014-04-16 2025-06-10 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US12256931B2 (en) 2014-04-16 2025-03-25 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US11883026B2 (en) 2014-04-16 2024-01-30 Cilag Gmbh International Fastener cartridge assemblies and staple retainer cover arrangements
US11717294B2 (en) 2014-04-16 2023-08-08 Cilag Gmbh International End effector arrangements comprising indicators
US11596406B2 (en) 2014-04-16 2023-03-07 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US11944307B2 (en) 2014-04-16 2024-04-02 Cilag Gmbh International Surgical stapling system including jaw windows
US11266409B2 (en) 2014-04-16 2022-03-08 Cilag Gmbh International Fastener cartridge comprising a sled including longitudinally-staggered ramps
US11918222B2 (en) 2014-04-16 2024-03-05 Cilag Gmbh International Stapling assembly having firing member viewing windows
US12274445B2 (en) 2014-04-16 2025-04-15 Cilag Gmbh International Fastener cartridges including extensions having different configurations
US11925353B2 (en) 2014-04-16 2024-03-12 Cilag Gmbh International Surgical stapling instrument comprising internal passage between stapling cartridge and elongate channel
US11382627B2 (en) 2014-04-16 2022-07-12 Cilag Gmbh International Surgical stapling assembly comprising a firing member including a lateral extension
US11382625B2 (en) 2014-04-16 2022-07-12 Cilag Gmbh International Fastener cartridge comprising non-uniform fasteners
US11974746B2 (en) 2014-04-16 2024-05-07 Cilag Gmbh International Anvil for use with a surgical stapling assembly
US12089849B2 (en) 2014-04-16 2024-09-17 Cilag Gmbh International Staple cartridges including a projection
US12042147B2 (en) 2014-09-05 2024-07-23 Cllag GmbH International Smart cartridge wake up operation and data retention
US12414768B2 (en) 2014-09-05 2025-09-16 Cilag Gmbh International Staple cartridge electrical contacts
US11311294B2 (en) 2014-09-05 2022-04-26 Cilag Gmbh International Powered medical device including measurement of closure state of jaws
US12336709B2 (en) 2014-09-05 2025-06-24 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11389162B2 (en) 2014-09-05 2022-07-19 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11071545B2 (en) 2014-09-05 2021-07-27 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11717297B2 (en) 2014-09-05 2023-08-08 Cilag Gmbh International Smart cartridge wake up operation and data retention
US11406386B2 (en) 2014-09-05 2022-08-09 Cilag Gmbh International End effector including magnetic and impedance sensors
US11653918B2 (en) 2014-09-05 2023-05-23 Cilag Gmbh International Local display of tissue parameter stabilization
US11076854B2 (en) 2014-09-05 2021-08-03 Cilag Gmbh International Smart cartridge wake up operation and data retention
US12076017B2 (en) 2014-09-18 2024-09-03 Cilag Gmbh International Surgical instrument including a deployable knife
US11523821B2 (en) 2014-09-26 2022-12-13 Cilag Gmbh International Method for creating a flexible staple line
US12016564B2 (en) 2014-09-26 2024-06-25 Cilag Gmbh International Circular fastener cartridges for applying radially expandable fastener lines
US12383259B2 (en) 2014-09-26 2025-08-12 Cilag Gmbh International Method for creating a flexible staple line
US11202633B2 (en) 2014-09-26 2021-12-21 Cilag Gmbh International Surgical stapling buttresses and adjunct materials
US11701114B2 (en) 2014-10-16 2023-07-18 Cilag Gmbh International Staple cartridge
US11931031B2 (en) 2014-10-16 2024-03-19 Cilag Gmbh International Staple cartridge comprising a deck including an upper surface and a lower surface
US11918210B2 (en) 2014-10-16 2024-03-05 Cilag Gmbh International Staple cartridge comprising a cartridge body including a plurality of wells
US12004741B2 (en) 2014-10-16 2024-06-11 Cilag Gmbh International Staple cartridge comprising a tissue thickness compensator
US11185325B2 (en) 2014-10-16 2021-11-30 Cilag Gmbh International End effector including different tissue gaps
US11931038B2 (en) 2014-10-29 2024-03-19 Cilag Gmbh International Cartridge assemblies for surgical staplers
US11141153B2 (en) 2014-10-29 2021-10-12 Cilag Gmbh International Staple cartridges comprising driver arrangements
US11864760B2 (en) 2014-10-29 2024-01-09 Cilag Gmbh International Staple cartridges comprising driver arrangements
US11457918B2 (en) 2014-10-29 2022-10-04 Cilag Gmbh International Cartridge assemblies for surgical staplers
US11241229B2 (en) 2014-10-29 2022-02-08 Cilag Gmbh International Staple cartridges comprising driver arrangements
US11337698B2 (en) 2014-11-06 2022-05-24 Cilag Gmbh International Staple cartridge comprising a releasable adjunct material
US11382628B2 (en) 2014-12-10 2022-07-12 Cilag Gmbh International Articulatable surgical instrument system
US12114859B2 (en) 2014-12-10 2024-10-15 Cilag Gmbh International Articulatable surgical instrument system
US11678877B2 (en) 2014-12-18 2023-06-20 Cilag Gmbh International Surgical instrument including a flexible support configured to support a flexible firing member
US11812958B2 (en) 2014-12-18 2023-11-14 Cilag Gmbh International Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors
US11547403B2 (en) 2014-12-18 2023-01-10 Cilag Gmbh International Surgical instrument having a laminate firing actuator and lateral buckling supports
US11547404B2 (en) 2014-12-18 2023-01-10 Cilag Gmbh International Surgical instrument assembly comprising a flexible articulation system
US11553911B2 (en) 2014-12-18 2023-01-17 Cilag Gmbh International Surgical instrument assembly comprising a flexible articulation system
US11517311B2 (en) 2014-12-18 2022-12-06 Cilag Gmbh International Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US12108950B2 (en) 2014-12-18 2024-10-08 Cilag Gmbh International Surgical instrument assembly comprising a flexible articulation system
US11571207B2 (en) 2014-12-18 2023-02-07 Cilag Gmbh International Surgical system including lateral supports for a flexible drive member
US12029419B2 (en) 2014-12-18 2024-07-09 Cilag Gmbh International Surgical instrument including a flexible support configured to support a flexible firing member
US11399831B2 (en) 2014-12-18 2022-08-02 Cilag Gmbh International Drive arrangements for articulatable surgical instruments
US11083453B2 (en) 2014-12-18 2021-08-10 Cilag Gmbh International Surgical stapling system including a flexible firing actuator and lateral buckling supports
US11154301B2 (en) 2015-02-27 2021-10-26 Cilag Gmbh International Modular stapling assembly
US11324506B2 (en) 2015-02-27 2022-05-10 Cilag Gmbh International Modular stapling assembly
US12076018B2 (en) 2015-02-27 2024-09-03 Cilag Gmbh International Modular stapling assembly
US11744588B2 (en) 2015-02-27 2023-09-05 Cilag Gmbh International Surgical stapling instrument including a removably attachable battery pack
US11350843B2 (en) 2015-03-06 2022-06-07 Cilag Gmbh International Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US12440208B2 (en) 2015-03-06 2025-10-14 Cilag Gmbh International Powered surgical instrument
US11224423B2 (en) 2015-03-06 2022-01-18 Cilag Gmbh International Smart sensors with local signal processing
US11426160B2 (en) 2015-03-06 2022-08-30 Cilag Gmbh International Smart sensors with local signal processing
US11944338B2 (en) 2015-03-06 2024-04-02 Cilag Gmbh International Multiple level thresholds to modify operation of powered surgical instruments
US11826132B2 (en) 2015-03-06 2023-11-28 Cilag Gmbh International Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US11109859B2 (en) 2015-03-06 2021-09-07 Cilag Gmbh International Surgical instrument comprising a lockable battery housing
US11918212B2 (en) 2015-03-31 2024-03-05 Cilag Gmbh International Surgical instrument with selectively disengageable drive systems
US11849946B2 (en) 2015-09-23 2023-12-26 Cilag Gmbh International Surgical stapler having downstream current-based motor control
US11490889B2 (en) 2015-09-23 2022-11-08 Cilag Gmbh International Surgical stapler having motor control based on an electrical parameter related to a motor current
US11344299B2 (en) 2015-09-23 2022-05-31 Cilag Gmbh International Surgical stapler having downstream current-based motor control
US11076929B2 (en) 2015-09-25 2021-08-03 Cilag Gmbh International Implantable adjunct systems for determining adjunct skew
US12245901B2 (en) 2015-09-25 2025-03-11 Cilag Gmbh International Implantable layer comprising boundary indicators
CN108136103B (zh) * 2015-09-29 2021-04-27 泰尔茂株式会社 医疗用具包装用容器、医疗用具包装体及预灌封注射器用外筒包装体
CN108136103A (zh) * 2015-09-29 2018-06-08 泰尔茂株式会社 医疗用具包装用容器、医疗用具包装体及预灌封注射器用外筒包装体
US11944308B2 (en) 2015-09-30 2024-04-02 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
US11553916B2 (en) 2015-09-30 2023-01-17 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
US11903586B2 (en) 2015-09-30 2024-02-20 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
US11890015B2 (en) 2015-09-30 2024-02-06 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
US12137912B2 (en) 2015-09-30 2024-11-12 Cilag Gmbh International Compressible adjunct with attachment regions
US11793522B2 (en) 2015-09-30 2023-10-24 Cilag Gmbh International Staple cartridge assembly including a compressible adjunct
US11712244B2 (en) 2015-09-30 2023-08-01 Cilag Gmbh International Implantable layer with spacer fibers
US11690623B2 (en) 2015-09-30 2023-07-04 Cilag Gmbh International Method for applying an implantable layer to a fastener cartridge
US11129613B2 (en) 2015-12-30 2021-09-28 Cilag Gmbh International Surgical instruments with separable motors and motor control circuits
US11083454B2 (en) 2015-12-30 2021-08-10 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US12324579B2 (en) 2015-12-30 2025-06-10 Cilag Gmbh International Mechanisms for compensating for battery pack failure in powered surgical instruments
US11058422B2 (en) 2015-12-30 2021-07-13 Cilag Gmbh International Mechanisms for compensating for battery pack failure in powered surgical instruments
US12156653B2 (en) 2015-12-30 2024-12-03 Cilag Gmbh International Surgical instruments with motor control circuits
US11759208B2 (en) 2015-12-30 2023-09-19 Cilag Gmbh International Mechanisms for compensating for battery pack failure in powered surgical instruments
US11484309B2 (en) 2015-12-30 2022-11-01 Cilag Gmbh International Surgical stapling system comprising a controller configured to cause a motor to reset a firing sequence
US11213293B2 (en) 2016-02-09 2022-01-04 Cilag Gmbh International Articulatable surgical instruments with single articulation link arrangements
US11523823B2 (en) 2016-02-09 2022-12-13 Cilag Gmbh International Surgical instruments with non-symmetrical articulation arrangements
US11730471B2 (en) 2016-02-09 2023-08-22 Cilag Gmbh International Articulatable surgical instruments with single articulation link arrangements
US11779336B2 (en) 2016-02-12 2023-10-10 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11344303B2 (en) 2016-02-12 2022-05-31 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11826045B2 (en) 2016-02-12 2023-11-28 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11224426B2 (en) 2016-02-12 2022-01-18 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11642125B2 (en) 2016-04-15 2023-05-09 Cilag Gmbh International Robotic surgical system including a user interface and a control circuit
US11284891B2 (en) 2016-04-15 2022-03-29 Cilag Gmbh International Surgical instrument with multiple program responses during a firing motion
US12144500B2 (en) 2016-04-15 2024-11-19 Cilag Gmbh International Surgical instrument with multiple program responses during a firing motion
US11051810B2 (en) 2016-04-15 2021-07-06 Cilag Gmbh International Modular surgical instrument with configurable operating mode
US11191545B2 (en) 2016-04-15 2021-12-07 Cilag Gmbh International Staple formation detection mechanisms
US11311292B2 (en) 2016-04-15 2022-04-26 Cilag Gmbh International Surgical instrument with detection sensors
US11350932B2 (en) 2016-04-15 2022-06-07 Cilag Gmbh International Surgical instrument with improved stop/start control during a firing motion
US11517306B2 (en) 2016-04-15 2022-12-06 Cilag Gmbh International Surgical instrument with detection sensors
US12440209B2 (en) 2016-04-15 2025-10-14 Cilag Gmbh International Surgical instrument with multiple program responses during a firing motion
US11607239B2 (en) 2016-04-15 2023-03-21 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US11931028B2 (en) 2016-04-15 2024-03-19 Cilag Gmbh International Surgical instrument with multiple program responses during a firing motion
US11179150B2 (en) 2016-04-15 2021-11-23 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US11317910B2 (en) 2016-04-15 2022-05-03 Cilag Gmbh International Surgical instrument with detection sensors
US11317917B2 (en) 2016-04-18 2022-05-03 Cilag Gmbh International Surgical stapling system comprising a lockable firing assembly
US12261471B2 (en) 2016-04-18 2025-03-25 Cilag Gmbh International Technologies for detection of drive train failures in a surgical instrument
US11350928B2 (en) 2016-04-18 2022-06-07 Cilag Gmbh International Surgical instrument comprising a tissue thickness lockout and speed control system
US11147554B2 (en) 2016-04-18 2021-10-19 Cilag Gmbh International Surgical instrument system comprising a magnetic lockout
US11811253B2 (en) 2016-04-18 2023-11-07 Cilag Gmbh International Surgical robotic system with fault state detection configurations based on motor current draw
US11559303B2 (en) 2016-04-18 2023-01-24 Cilag Gmbh International Cartridge lockout arrangements for rotary powered surgical cutting and stapling instruments
US12171507B2 (en) 2016-08-16 2024-12-24 Cilag Gmbh International Surgical tool with manual control of end effector jaws
US11191539B2 (en) 2016-12-21 2021-12-07 Cilag Gmbh International Shaft assembly comprising a manually-operable retraction system for use with a motorized surgical instrument system
US12011166B2 (en) 2016-12-21 2024-06-18 Cilag Gmbh International Articulatable surgical stapling instruments
US12274442B2 (en) 2016-12-21 2025-04-15 Cilag Gmbh International Surgical staple cartridge alignment features
US12185946B2 (en) 2016-12-21 2025-01-07 Cilag Gmbh International Articulatable surgical stapling instruments
US11191540B2 (en) 2016-12-21 2021-12-07 Cilag Gmbh International Protective cover arrangements for a joint interface between a movable jaw and actuator shaft of a surgical instrument
US11191543B2 (en) 2016-12-21 2021-12-07 Cilag Gmbh International Assembly comprising a lock
US11419606B2 (en) 2016-12-21 2022-08-23 Cilag Gmbh International Shaft assembly comprising a clutch configured to adapt the output of a rotary firing member to two different systems
US12245764B2 (en) 2016-12-21 2025-03-11 Cilag Gmbh International Shaft assembly comprising a lockout
US11918215B2 (en) 2016-12-21 2024-03-05 Cilag Gmbh International Staple cartridge with array of staple pockets
US11653917B2 (en) 2016-12-21 2023-05-23 Cilag Gmbh International Surgical stapling systems
US11350934B2 (en) 2016-12-21 2022-06-07 Cilag Gmbh International Staple forming pocket arrangement to accommodate different types of staples
US11766260B2 (en) 2016-12-21 2023-09-26 Cilag Gmbh International Methods of stapling tissue
US11766259B2 (en) 2016-12-21 2023-09-26 Cilag Gmbh International Method of deforming staples from two different types of staple cartridges with the same surgical stapling instrument
US11369376B2 (en) 2016-12-21 2022-06-28 Cilag Gmbh International Surgical stapling systems
US11350935B2 (en) 2016-12-21 2022-06-07 Cilag Gmbh International Surgical tool assemblies with closure stroke reduction features
US12226100B2 (en) 2016-12-21 2025-02-18 Cilag Gmbh International Method of deforming staples from two different types of staple cartridges with the same surgical stapling instrument
US11090048B2 (en) 2016-12-21 2021-08-17 Cilag Gmbh International Method for resetting a fuse of a surgical instrument shaft
US11849948B2 (en) 2016-12-21 2023-12-26 Cilag Gmbh International Method for resetting a fuse of a surgical instrument shaft
US12004745B2 (en) 2016-12-21 2024-06-11 Cilag Gmbh International Surgical instrument system comprising an end effector lockout and a firing assembly lockout
US11224428B2 (en) 2016-12-21 2022-01-18 Cilag Gmbh International Surgical stapling systems
US11701115B2 (en) 2016-12-21 2023-07-18 Cilag Gmbh International Methods of stapling tissue
US11957344B2 (en) 2016-12-21 2024-04-16 Cilag Gmbh International Surgical stapler having rows of obliquely oriented staples
US11497499B2 (en) 2016-12-21 2022-11-15 Cilag Gmbh International Articulatable surgical stapling instruments
US11564688B2 (en) 2016-12-21 2023-01-31 Cilag Gmbh International Robotic surgical tool having a retraction mechanism
US11179155B2 (en) 2016-12-21 2021-11-23 Cilag Gmbh International Anvil arrangements for surgical staplers
US11992213B2 (en) 2016-12-21 2024-05-28 Cilag Gmbh International Surgical stapling instruments with replaceable staple cartridges
US11931034B2 (en) 2016-12-21 2024-03-19 Cilag Gmbh International Surgical stapling instruments with smart staple cartridges
US11160553B2 (en) 2016-12-21 2021-11-02 Cilag Gmbh International Surgical stapling systems
US11317913B2 (en) 2016-12-21 2022-05-03 Cilag Gmbh International Lockout arrangements for surgical end effectors and replaceable tool assemblies
US11160551B2 (en) 2016-12-21 2021-11-02 Cilag Gmbh International Articulatable surgical stapling instruments
US11871939B2 (en) 2017-06-20 2024-01-16 Cilag Gmbh International Method for closed loop control of motor velocity of a surgical stapling and cutting instrument
US12490980B2 (en) 2017-06-20 2025-12-09 Cilag Gmbh International Surgical instrument having controllable articulation velocity
US11653914B2 (en) 2017-06-20 2023-05-23 Cilag Gmbh International Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument according to articulation angle of end effector
US11090046B2 (en) 2017-06-20 2021-08-17 Cilag Gmbh International Systems and methods for controlling displacement member motion of a surgical stapling and cutting instrument
US11672532B2 (en) 2017-06-20 2023-06-13 Cilag Gmbh International Techniques for adaptive control of motor velocity of a surgical stapling and cutting instrument
US11793513B2 (en) 2017-06-20 2023-10-24 Cilag Gmbh International Systems and methods for controlling motor speed according to user input for a surgical instrument
US12274438B2 (en) 2017-06-20 2025-04-15 Cilag Gmbh International Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument according to articulation angle of end effector
US11517325B2 (en) 2017-06-20 2022-12-06 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured displacement distance traveled over a specified time interval
US11382638B2 (en) 2017-06-20 2022-07-12 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified displacement distance
US11213302B2 (en) 2017-06-20 2022-01-04 Cilag Gmbh International Method for closed loop control of motor velocity of a surgical stapling and cutting instrument
US12207820B2 (en) 2017-06-27 2025-01-28 Cilag Gmbh International Surgical anvil arrangements
US12161326B2 (en) 2017-06-27 2024-12-10 Cilag Gmbh International Surgical anvil manufacturing methods
US11266405B2 (en) 2017-06-27 2022-03-08 Cilag Gmbh International Surgical anvil manufacturing methods
US11766258B2 (en) 2017-06-27 2023-09-26 Cilag Gmbh International Surgical anvil arrangements
US11141154B2 (en) 2017-06-27 2021-10-12 Cilag Gmbh International Surgical end effectors and anvils
US11324503B2 (en) 2017-06-27 2022-05-10 Cilag Gmbh International Surgical firing member arrangements
US11090049B2 (en) 2017-06-27 2021-08-17 Cilag Gmbh International Staple forming pocket arrangements
US11642128B2 (en) 2017-06-28 2023-05-09 Cilag Gmbh International Method for articulating a surgical instrument
US12324581B2 (en) 2017-06-28 2025-06-10 Cilag Gmbh International Surgical instrument comprising selectively actuatable rotatable couplers
US11826048B2 (en) 2017-06-28 2023-11-28 Cilag Gmbh International Surgical instrument comprising selectively actuatable rotatable couplers
US11478242B2 (en) 2017-06-28 2022-10-25 Cilag Gmbh International Jaw retainer arrangement for retaining a pivotable surgical instrument jaw in pivotable retaining engagement with a second surgical instrument jaw
US11696759B2 (en) 2017-06-28 2023-07-11 Cilag Gmbh International Surgical stapling instruments comprising shortened staple cartridge noses
US11083455B2 (en) 2017-06-28 2021-08-10 Cilag Gmbh International Surgical instrument comprising an articulation system ratio
US11564686B2 (en) 2017-06-28 2023-01-31 Cilag Gmbh International Surgical shaft assemblies with flexible interfaces
US11678880B2 (en) 2017-06-28 2023-06-20 Cilag Gmbh International Surgical instrument comprising a shaft including a housing arrangement
US12446877B2 (en) 2017-06-28 2025-10-21 Cilag Gmbh International Surgical instrument having articulation lock actuated by closure tube displacement
US11259805B2 (en) 2017-06-28 2022-03-01 Cilag Gmbh International Surgical instrument comprising firing member supports
US11484310B2 (en) 2017-06-28 2022-11-01 Cilag Gmbh International Surgical instrument comprising a shaft including a closure tube profile
US11529140B2 (en) 2017-06-28 2022-12-20 Cilag Gmbh International Surgical instrument lockout arrangement
US11246592B2 (en) 2017-06-28 2022-02-15 Cilag Gmbh International Surgical instrument comprising an articulation system lockable to a frame
USD1018577S1 (en) 2017-06-28 2024-03-19 Cilag Gmbh International Display screen or portion thereof with a graphical user interface for a surgical instrument
US11890005B2 (en) 2017-06-29 2024-02-06 Cilag Gmbh International Methods for closed loop velocity control for robotic surgical instrument
US11304695B2 (en) 2017-08-03 2022-04-19 Cilag Gmbh International Surgical system shaft interconnection
US11944300B2 (en) 2017-08-03 2024-04-02 Cilag Gmbh International Method for operating a surgical system bailout
US11974742B2 (en) 2017-08-03 2024-05-07 Cilag Gmbh International Surgical system comprising an articulation bailout
US11471155B2 (en) 2017-08-03 2022-10-18 Cilag Gmbh International Surgical system bailout
US11998199B2 (en) 2017-09-29 2024-06-04 Cllag GmbH International System and methods for controlling a display of a surgical instrument
US11399829B2 (en) 2017-09-29 2022-08-02 Cilag Gmbh International Systems and methods of initiating a power shutdown mode for a surgical instrument
US12076011B2 (en) 2017-10-30 2024-09-03 Cilag Gmbh International Surgical stapler knife motion controls
US11090075B2 (en) 2017-10-30 2021-08-17 Cilag Gmbh International Articulation features for surgical end effector
US11134944B2 (en) 2017-10-30 2021-10-05 Cilag Gmbh International Surgical stapler knife motion controls
US11963680B2 (en) 2017-10-31 2024-04-23 Cilag Gmbh International Cartridge body design with force reduction based on firing completion
US11478244B2 (en) 2017-10-31 2022-10-25 Cilag Gmbh International Cartridge body design with force reduction based on firing completion
US11896222B2 (en) 2017-12-15 2024-02-13 Cilag Gmbh International Methods of operating surgical end effectors
US11197670B2 (en) 2017-12-15 2021-12-14 Cilag Gmbh International Surgical end effectors with pivotal jaws configured to touch at their respective distal ends when fully closed
US11071543B2 (en) 2017-12-15 2021-07-27 Cilag Gmbh International Surgical end effectors with clamping assemblies configured to increase jaw aperture ranges
US12076096B2 (en) 2017-12-19 2024-09-03 Cilag Gmbh International Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly
US11284953B2 (en) 2017-12-19 2022-03-29 Cilag Gmbh International Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly
US11147547B2 (en) 2017-12-21 2021-10-19 Cilag Gmbh International Surgical stapler comprising storable cartridges having different staple sizes
US11179151B2 (en) 2017-12-21 2021-11-23 Cilag Gmbh International Surgical instrument comprising a display
US11751867B2 (en) 2017-12-21 2023-09-12 Cilag Gmbh International Surgical instrument comprising sequenced systems
US11883019B2 (en) 2017-12-21 2024-01-30 Cilag Gmbh International Stapling instrument comprising a staple feeding system
US11179152B2 (en) 2017-12-21 2021-11-23 Cilag Gmbh International Surgical instrument comprising a tissue grasping system
US11076853B2 (en) 2017-12-21 2021-08-03 Cilag Gmbh International Systems and methods of displaying a knife position during transection for a surgical instrument
US11311290B2 (en) 2017-12-21 2022-04-26 Cilag Gmbh International Surgical instrument comprising an end effector dampener
US11583274B2 (en) 2017-12-21 2023-02-21 Cilag Gmbh International Self-guiding stapling instrument
US11337691B2 (en) 2017-12-21 2022-05-24 Cilag Gmbh International Surgical instrument configured to determine firing path
US11369368B2 (en) 2017-12-21 2022-06-28 Cilag Gmbh International Surgical instrument comprising synchronized drive systems
US11576668B2 (en) 2017-12-21 2023-02-14 Cilag Gmbh International Staple instrument comprising a firing path display
US12336705B2 (en) 2017-12-21 2025-06-24 Cilag Gmbh International Continuous use self-propelled stapling instrument
US11849939B2 (en) 2017-12-21 2023-12-26 Cilag Gmbh International Continuous use self-propelled stapling instrument
US20210015579A1 (en) * 2018-03-30 2021-01-21 Bemis Company, Inc. Package for pvc products
US11324501B2 (en) 2018-08-20 2022-05-10 Cilag Gmbh International Surgical stapling devices with improved closure members
US11957339B2 (en) 2018-08-20 2024-04-16 Cilag Gmbh International Method for fabricating surgical stapler anvils
US12076008B2 (en) 2018-08-20 2024-09-03 Cilag Gmbh International Method for operating a powered articulatable surgical instrument
US12262888B2 (en) 2018-08-20 2025-04-01 Cilag Gmbh International Surgical instruments with progressive jaw closure arrangements
US11253256B2 (en) 2018-08-20 2022-02-22 Cilag Gmbh International Articulatable motor powered surgical instruments with dedicated articulation motor arrangements
US11291440B2 (en) 2018-08-20 2022-04-05 Cilag Gmbh International Method for operating a powered articulatable surgical instrument
US11207065B2 (en) 2018-08-20 2021-12-28 Cilag Gmbh International Method for fabricating surgical stapler anvils
CN111202587A (zh) * 2018-11-21 2020-05-29 海隆医用产品(昆山)有限公司 一种可加热塑料盆
US11696761B2 (en) 2019-03-25 2023-07-11 Cilag Gmbh International Firing drive arrangements for surgical systems
US12290259B2 (en) 2019-03-25 2025-05-06 Cilag Gmbh International Firing drive arrangements for surgical systems
US11147553B2 (en) 2019-03-25 2021-10-19 Cilag Gmbh International Firing drive arrangements for surgical systems
US11147551B2 (en) 2019-03-25 2021-10-19 Cilag Gmbh International Firing drive arrangements for surgical systems
US11172929B2 (en) 2019-03-25 2021-11-16 Cilag Gmbh International Articulation drive arrangements for surgical systems
US11253254B2 (en) 2019-04-30 2022-02-22 Cilag Gmbh International Shaft rotation actuator on a surgical instrument
US11471157B2 (en) 2019-04-30 2022-10-18 Cilag Gmbh International Articulation control mapping for a surgical instrument
US11903581B2 (en) 2019-04-30 2024-02-20 Cilag Gmbh International Methods for stapling tissue using a surgical instrument
US11452528B2 (en) 2019-04-30 2022-09-27 Cilag Gmbh International Articulation actuators for a surgical instrument
US11432816B2 (en) 2019-04-30 2022-09-06 Cilag Gmbh International Articulation pin for a surgical instrument
US11426251B2 (en) 2019-04-30 2022-08-30 Cilag Gmbh International Articulation directional lights on a surgical instrument
US11648009B2 (en) 2019-04-30 2023-05-16 Cilag Gmbh International Rotatable jaw tip for a surgical instrument
US11350938B2 (en) 2019-06-28 2022-06-07 Cilag Gmbh International Surgical instrument comprising an aligned rfid sensor
US11478241B2 (en) 2019-06-28 2022-10-25 Cilag Gmbh International Staple cartridge including projections
CN114007539A (zh) * 2019-06-28 2022-02-01 西拉格国际有限公司 包括微粒捕集器的包装组件
US11553919B2 (en) 2019-06-28 2023-01-17 Cilag Gmbh International Method for authenticating the compatibility of a staple cartridge with a surgical instrument
US11241235B2 (en) 2019-06-28 2022-02-08 Cilag Gmbh International Method of using multiple RFID chips with a surgical assembly
US11246678B2 (en) 2019-06-28 2022-02-15 Cilag Gmbh International Surgical stapling system having a frangible RFID tag
US11224497B2 (en) 2019-06-28 2022-01-18 Cilag Gmbh International Surgical systems with multiple RFID tags
US11660163B2 (en) 2019-06-28 2023-05-30 Cilag Gmbh International Surgical system with RFID tags for updating motor assembly parameters
US11638587B2 (en) 2019-06-28 2023-05-02 Cilag Gmbh International RFID identification systems for surgical instruments
US11684434B2 (en) 2019-06-28 2023-06-27 Cilag Gmbh International Surgical RFID assemblies for instrument operational setting control
US11259803B2 (en) 2019-06-28 2022-03-01 Cilag Gmbh International Surgical stapling system having an information encryption protocol
US11853835B2 (en) 2019-06-28 2023-12-26 Cilag Gmbh International RFID identification systems for surgical instruments
US11291451B2 (en) 2019-06-28 2022-04-05 Cilag Gmbh International Surgical instrument with battery compatibility verification functionality
US11553971B2 (en) 2019-06-28 2023-01-17 Cilag Gmbh International Surgical RFID assemblies for display and communication
JP7500623B2 (ja) 2019-06-28 2024-06-17 シラグ・ゲーエムベーハー・インターナショナル 微粒子トラップを含む包装アセンブリ
US11523822B2 (en) 2019-06-28 2022-12-13 Cilag Gmbh International Battery pack including a circuit interrupter
US11298132B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Inlernational Staple cartridge including a honeycomb extension
US11298127B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Interational Surgical stapling system having a lockout mechanism for an incompatible cartridge
US11744593B2 (en) 2019-06-28 2023-09-05 Cilag Gmbh International Method for authenticating the compatibility of a staple cartridge with a surgical instrument
US11051807B2 (en) 2019-06-28 2021-07-06 Cilag Gmbh International Packaging assembly including a particulate trap
US11684369B2 (en) 2019-06-28 2023-06-27 Cilag Gmbh International Method of using multiple RFID chips with a surgical assembly
US11497492B2 (en) 2019-06-28 2022-11-15 Cilag Gmbh International Surgical instrument including an articulation lock
US12004740B2 (en) 2019-06-28 2024-06-11 Cilag Gmbh International Surgical stapling system having an information decryption protocol
US11376098B2 (en) 2019-06-28 2022-07-05 Cilag Gmbh International Surgical instrument system comprising an RFID system
US11399837B2 (en) 2019-06-28 2022-08-02 Cilag Gmbh International Mechanisms for motor control adjustments of a motorized surgical instrument
US11229437B2 (en) 2019-06-28 2022-01-25 Cilag Gmbh International Method for authenticating the compatibility of a staple cartridge with a surgical instrument
US11426167B2 (en) 2019-06-28 2022-08-30 Cilag Gmbh International Mechanisms for proper anvil attachment surgical stapling head assembly
JP2022538620A (ja) * 2019-06-28 2022-09-05 シラグ・ゲーエムベーハー・インターナショナル 微粒子トラップを含む包装アセンブリ
EP3756611A1 (fr) * 2019-06-28 2020-12-30 Ethicon LLC Ensemble de conditionnement comprenant un piège à particules
US11771419B2 (en) 2019-06-28 2023-10-03 Cilag Gmbh International Packaging for a replaceable component of a surgical stapling system
US12458455B2 (en) 2019-06-28 2025-11-04 Cilag Gmbh International Surgical RFID assemblies for instrument operational setting control
US11464601B2 (en) 2019-06-28 2022-10-11 Cilag Gmbh International Surgical instrument comprising an RFID system for tracking a movable component
US11627959B2 (en) 2019-06-28 2023-04-18 Cilag Gmbh International Surgical instruments including manual and powered system lockouts
CN114007539B (zh) * 2019-06-28 2025-02-07 西拉格国际有限公司 包括微粒捕集器的包装组件
WO2020261015A1 (fr) * 2019-06-28 2020-12-30 Ethicon Llc Ensemble d'emballage comprenant un piège à particules
WO2021080895A1 (fr) * 2019-10-21 2021-04-29 Covestro Llc Matériaux de conditionnement orthopédique
CN114555367A (zh) * 2019-10-21 2022-05-27 科思创有限公司 骨科包装材料
US11504122B2 (en) 2019-12-19 2022-11-22 Cilag Gmbh International Surgical instrument comprising a nested firing member
US11304696B2 (en) 2019-12-19 2022-04-19 Cilag Gmbh International Surgical instrument comprising a powered articulation system
US11911032B2 (en) 2019-12-19 2024-02-27 Cilag Gmbh International Staple cartridge comprising a seating cam
US11701111B2 (en) 2019-12-19 2023-07-18 Cilag Gmbh International Method for operating a surgical stapling instrument
US11576672B2 (en) 2019-12-19 2023-02-14 Cilag Gmbh International Surgical instrument comprising a closure system including a closure member and an opening member driven by a drive screw
US11446029B2 (en) 2019-12-19 2022-09-20 Cilag Gmbh International Staple cartridge comprising projections extending from a curved deck surface
US11607219B2 (en) 2019-12-19 2023-03-21 Cilag Gmbh International Staple cartridge comprising a detachable tissue cutting knife
US11464512B2 (en) 2019-12-19 2022-10-11 Cilag Gmbh International Staple cartridge comprising a curved deck surface
US11844520B2 (en) 2019-12-19 2023-12-19 Cilag Gmbh International Staple cartridge comprising driver retention members
US11529139B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Motor driven surgical instrument
US11291447B2 (en) 2019-12-19 2022-04-05 Cilag Gmbh International Stapling instrument comprising independent jaw closing and staple firing systems
US11529137B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Staple cartridge comprising driver retention members
US12035913B2 (en) 2019-12-19 2024-07-16 Cilag Gmbh International Staple cartridge comprising a deployable knife
US11559304B2 (en) 2019-12-19 2023-01-24 Cilag Gmbh International Surgical instrument comprising a rapid closure mechanism
US11931033B2 (en) 2019-12-19 2024-03-19 Cilag Gmbh International Staple cartridge comprising a latch lockout
US11234698B2 (en) 2019-12-19 2022-02-01 Cilag Gmbh International Stapling system comprising a clamp lockout and a firing lockout
USD974560S1 (en) 2020-06-02 2023-01-03 Cilag Gmbh International Staple cartridge
USD966512S1 (en) 2020-06-02 2022-10-11 Cilag Gmbh International Staple cartridge
USD975850S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
USD975278S1 (en) 2020-06-02 2023-01-10 Cilag Gmbh International Staple cartridge
USD975851S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
USD976401S1 (en) 2020-06-02 2023-01-24 Cilag Gmbh International Staple cartridge
USD967421S1 (en) 2020-06-02 2022-10-18 Cilag Gmbh International Staple cartridge
US12161323B2 (en) 2020-07-28 2024-12-10 Cilag Gmbh International Surgical instruments with torsion spine drive arrangements
US11974741B2 (en) 2020-07-28 2024-05-07 Cilag Gmbh International Surgical instruments with differential articulation joint arrangements for accommodating flexible actuators
US11737748B2 (en) 2020-07-28 2023-08-29 Cilag Gmbh International Surgical instruments with double spherical articulation joints with pivotable links
US12064107B2 (en) 2020-07-28 2024-08-20 Cilag Gmbh International Articulatable surgical instruments with articulation joints comprising flexible exoskeleton arrangements
US12220126B2 (en) 2020-07-28 2025-02-11 Cilag Gmbh International Surgical instruments with double pivot articulation joint arrangements
US11826013B2 (en) 2020-07-28 2023-11-28 Cilag Gmbh International Surgical instruments with firing member closure features
US11857182B2 (en) 2020-07-28 2024-01-02 Cilag Gmbh International Surgical instruments with combination function articulation joint arrangements
US11864756B2 (en) 2020-07-28 2024-01-09 Cilag Gmbh International Surgical instruments with flexible ball chain drive arrangements
US11871925B2 (en) 2020-07-28 2024-01-16 Cilag Gmbh International Surgical instruments with dual spherical articulation joint arrangements
US11638582B2 (en) 2020-07-28 2023-05-02 Cilag Gmbh International Surgical instruments with torsion spine drive arrangements
US11660090B2 (en) 2020-07-28 2023-05-30 Cllag GmbH International Surgical instruments with segmented flexible drive arrangements
US11883024B2 (en) 2020-07-28 2024-01-30 Cilag Gmbh International Method of operating a surgical instrument
US11779330B2 (en) 2020-10-29 2023-10-10 Cilag Gmbh International Surgical instrument comprising a jaw alignment system
USD980425S1 (en) 2020-10-29 2023-03-07 Cilag Gmbh International Surgical instrument assembly
US11517390B2 (en) 2020-10-29 2022-12-06 Cilag Gmbh International Surgical instrument comprising a limited travel switch
USD1013170S1 (en) 2020-10-29 2024-01-30 Cilag Gmbh International Surgical instrument assembly
US11931025B2 (en) 2020-10-29 2024-03-19 Cilag Gmbh International Surgical instrument comprising a releasable closure drive lock
US11896217B2 (en) 2020-10-29 2024-02-13 Cilag Gmbh International Surgical instrument comprising an articulation lock
US11452526B2 (en) 2020-10-29 2022-09-27 Cilag Gmbh International Surgical instrument comprising a staged voltage regulation start-up system
US12029421B2 (en) 2020-10-29 2024-07-09 Cilag Gmbh International Surgical instrument comprising a staged voltage regulation start-up system
US12053175B2 (en) 2020-10-29 2024-08-06 Cilag Gmbh International Surgical instrument comprising a stowed closure actuator stop
US11534259B2 (en) 2020-10-29 2022-12-27 Cilag Gmbh International Surgical instrument comprising an articulation indicator
US11717289B2 (en) 2020-10-29 2023-08-08 Cilag Gmbh International Surgical instrument comprising an indicator which indicates that an articulation drive is actuatable
US12226099B2 (en) 2020-10-29 2025-02-18 Cilag Gmbh International Surgical stapler with pulse width modulated driven adjustable speed staple firing stroke
US12076194B2 (en) 2020-10-29 2024-09-03 Cilag Gmbh International Surgical instrument comprising an articulation indicator
US11617577B2 (en) 2020-10-29 2023-04-04 Cilag Gmbh International Surgical instrument comprising a sensor configured to sense whether an articulation drive of the surgical instrument is actuatable
US11844518B2 (en) 2020-10-29 2023-12-19 Cilag Gmbh International Method for operating a surgical instrument
US11678882B2 (en) 2020-12-02 2023-06-20 Cilag Gmbh International Surgical instruments with interactive features to remedy incidental sled movements
US11944296B2 (en) 2020-12-02 2024-04-02 Cilag Gmbh International Powered surgical instruments with external connectors
US11627960B2 (en) 2020-12-02 2023-04-18 Cilag Gmbh International Powered surgical instruments with smart reload with separately attachable exteriorly mounted wiring connections
US12232724B2 (en) 2020-12-02 2025-02-25 Cilag Gmbh International Surgical instruments with sled location detection and adjustment features
US11737751B2 (en) 2020-12-02 2023-08-29 Cilag Gmbh International Devices and methods of managing energy dissipated within sterile barriers of surgical instrument housings
US12471982B2 (en) 2020-12-02 2025-11-18 Cilag Gmbh International Method for tissue treatment by surgical instrument
US11653915B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Surgical instruments with sled location detection and adjustment features
US11890010B2 (en) 2020-12-02 2024-02-06 Cllag GmbH International Dual-sided reinforced reload for surgical instruments
US11653920B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Powered surgical instruments with communication interfaces through sterile barrier
US12016559B2 (en) 2020-12-02 2024-06-25 Cllag GmbH International Powered surgical instruments with communication interfaces through sterile barrier
US12171427B2 (en) 2020-12-02 2024-12-24 Cilag Gmbh International Powered surgical instruments with smart reload with separately attachable exteriorly mounted wiring connections
US12369912B2 (en) 2020-12-02 2025-07-29 Cilag Gmbh International Surgical instruments with interactive features to remedy incidental sled movements
US11744581B2 (en) 2020-12-02 2023-09-05 Cilag Gmbh International Powered surgical instruments with multi-phase tissue treatment
US11849943B2 (en) 2020-12-02 2023-12-26 Cilag Gmbh International Surgical instrument with cartridge release mechanisms
US12133648B2 (en) 2020-12-02 2024-11-05 Cilag Gmbh International Surgical instrument with cartridge release mechanisms
RU2847337C1 (ru) * 2020-12-17 2025-10-03 Цобеле Холдинг Спа Контейнер для рассеивания летучих веществ
WO2022129510A1 (fr) * 2020-12-17 2022-06-23 Zobele Holding Spa Récipient de diffusion de substances volatiles
EP4015071A1 (fr) * 2020-12-17 2022-06-22 Zobele Holding SpA Récipient pour la diffusion de substances volatiles
US11730473B2 (en) 2021-02-26 2023-08-22 Cilag Gmbh International Monitoring of manufacturing life-cycle
US12108951B2 (en) 2021-02-26 2024-10-08 Cilag Gmbh International Staple cartridge comprising a sensing array and a temperature control system
US12035912B2 (en) 2021-02-26 2024-07-16 Cilag Gmbh International Adjustable communication based on available bandwidth and power capacity
US12144501B2 (en) 2021-02-26 2024-11-19 Cilag Gmbh International Monitoring of manufacturing life-cycle
US12357309B2 (en) 2021-02-26 2025-07-15 Cilag Gmbh International Staple cartridge comprising a power management circuit
US11749877B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Stapling instrument comprising a signal antenna
US12035911B2 (en) 2021-02-26 2024-07-16 Cilag Gmbh International Stapling instrument comprising a separate power antenna and a data transfer antenna
US11723657B2 (en) 2021-02-26 2023-08-15 Cilag Gmbh International Adjustable communication based on available bandwidth and power capacity
US12035910B2 (en) 2021-02-26 2024-07-16 Cllag GmbH International Monitoring of internal systems to detect and track cartridge motion status
US11812964B2 (en) 2021-02-26 2023-11-14 Cilag Gmbh International Staple cartridge comprising a power management circuit
US11980362B2 (en) 2021-02-26 2024-05-14 Cilag Gmbh International Surgical instrument system comprising a power transfer coil
US11925349B2 (en) 2021-02-26 2024-03-12 Cilag Gmbh International Adjustment to transfer parameters to improve available power
US11744583B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Distal communication array to tune frequency of RF systems
US11751869B2 (en) 2021-02-26 2023-09-12 Cilag Gmbh International Monitoring of multiple sensors over time to detect moving characteristics of tissue
US11950777B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Staple cartridge comprising an information access control system
US12369909B2 (en) 2021-02-26 2025-07-29 Cilag Gmbh International Monitoring of multiple sensors over time to detect moving characteristics of tissue
US12324580B2 (en) 2021-02-26 2025-06-10 Cilag Gmbh International Method of powering and communicating with a staple cartridge
US11793514B2 (en) 2021-02-26 2023-10-24 Cilag Gmbh International Staple cartridge comprising sensor array which may be embedded in cartridge body
US11950779B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Method of powering and communicating with a staple cartridge
US11701113B2 (en) 2021-02-26 2023-07-18 Cilag Gmbh International Stapling instrument comprising a separate power antenna and a data transfer antenna
US11696757B2 (en) 2021-02-26 2023-07-11 Cilag Gmbh International Monitoring of internal systems to detect and track cartridge motion status
US11826042B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Surgical instrument comprising a firing drive including a selectable leverage mechanism
US12023026B2 (en) 2021-03-22 2024-07-02 Cilag Gmbh International Staple cartridge comprising a firing lockout
US12042146B2 (en) 2021-03-22 2024-07-23 Cilag Gmbh International Surgical stapling instrument comprising a retraction system
US11806011B2 (en) 2021-03-22 2023-11-07 Cilag Gmbh International Stapling instrument comprising tissue compression systems
US11717291B2 (en) 2021-03-22 2023-08-08 Cilag Gmbh International Staple cartridge comprising staples configured to apply different tissue compression
US11759202B2 (en) 2021-03-22 2023-09-19 Cilag Gmbh International Staple cartridge comprising an implantable layer
US11723658B2 (en) 2021-03-22 2023-08-15 Cilag Gmbh International Staple cartridge comprising a firing lockout
US11826012B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Stapling instrument comprising a pulsed motor-driven firing rack
US11737749B2 (en) 2021-03-22 2023-08-29 Cilag Gmbh International Surgical stapling instrument comprising a retraction system
US11849945B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Rotary-driven surgical stapling assembly comprising eccentrically driven firing member
US12102323B2 (en) 2021-03-24 2024-10-01 Cilag Gmbh International Rotary-driven surgical stapling assembly comprising a floatable component
US11896218B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Method of using a powered stapling device
US11903582B2 (en) 2021-03-24 2024-02-20 Cilag Gmbh International Leveraging surfaces for cartridge installation
US11744603B2 (en) 2021-03-24 2023-09-05 Cilag Gmbh International Multi-axis pivot joints for surgical instruments and methods for manufacturing same
US11944336B2 (en) 2021-03-24 2024-04-02 Cilag Gmbh International Joint arrangements for multi-planar alignment and support of operational drive shafts in articulatable surgical instruments
US11832816B2 (en) 2021-03-24 2023-12-05 Cilag Gmbh International Surgical stapling assembly comprising nonplanar staples and planar staples
US11793516B2 (en) 2021-03-24 2023-10-24 Cilag Gmbh International Surgical staple cartridge comprising longitudinal support beam
US11896219B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Mating features between drivers and underside of a cartridge deck
US11849944B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Drivers for fastener cartridge assemblies having rotary drive screws
US11786239B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Surgical instrument articulation joint arrangements comprising multiple moving linkage features
US11786243B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Firing members having flexible portions for adapting to a load during a surgical firing stroke
EP4091950A1 (fr) * 2021-05-18 2022-11-23 Gerresheimer Glas GmbH Récipient pour unités d'emballage
US12466629B2 (en) 2021-05-18 2025-11-11 Gerresheimer Glas Gmbh Container for packaging units
US12319466B2 (en) 2021-05-18 2025-06-03 Gerresheimer Glas Gmbh Transporting packaging units
US12286270B2 (en) 2021-05-18 2025-04-29 Gerresheimer Glas Gmbh Transporting packaging units
US12006125B2 (en) 2021-05-18 2024-06-11 Gerresheimer Glas Gmbh Container for packaging units
US11723662B2 (en) 2021-05-28 2023-08-15 Cilag Gmbh International Stapling instrument comprising an articulation control display
US11998201B2 (en) 2021-05-28 2024-06-04 Cilag CmbH International Stapling instrument comprising a firing lockout
US11826047B2 (en) 2021-05-28 2023-11-28 Cilag Gmbh International Stapling instrument comprising jaw mounts
US11918217B2 (en) 2021-05-28 2024-03-05 Cilag Gmbh International Stapling instrument comprising a staple cartridge insertion stop
US11957337B2 (en) 2021-10-18 2024-04-16 Cilag Gmbh International Surgical stapling assembly with offset ramped drive surfaces
US11877745B2 (en) 2021-10-18 2024-01-23 Cilag Gmbh International Surgical stapling assembly having longitudinally-repeating staple leg clusters
US11980363B2 (en) 2021-10-18 2024-05-14 Cilag Gmbh International Row-to-row staple array variations
US12239317B2 (en) 2021-10-18 2025-03-04 Cilag Gmbh International Anvil comprising an arrangement of forming pockets proximal to tissue stop
US12432790B2 (en) 2021-10-28 2025-09-30 Cilag Gmbh International Method and device for transmitting UART communications over a security short range wireless communication
US12089841B2 (en) 2021-10-28 2024-09-17 Cilag CmbH International Staple cartridge identification systems
US11937816B2 (en) 2021-10-28 2024-03-26 Cilag Gmbh International Electrical lead arrangements for surgical instruments
TWI858817B (zh) * 2022-07-18 2024-10-11 德商格雷斯海姆格拉斯有限責任公司 醫療容器包裝
JP2024015988A (ja) * 2022-07-18 2024-02-06 ゲレスハイマー グラス ゲーエムベーハー 医療用容器パッケージ
JP2024015989A (ja) * 2022-07-18 2024-02-06 ゲレスハイマー グラス ゲーエムベーハー 医療用容器パッケージ
US12446987B2 (en) 2022-07-18 2025-10-21 Gerresheimer Glas Gmbh Medical container packaging
JP7556104B2 (ja) 2022-07-18 2024-09-25 ゲレスハイマー グラス ゲーエムベーハー 医療用容器パッケージ
EP4309695A1 (fr) * 2022-07-18 2024-01-24 Gerresheimer Glas GmbH Emballage de conteneur médical
EP4309696A1 (fr) * 2022-07-18 2024-01-24 Gerresheimer Glas GmbH Emballage de conteneur médical
TWI858822B (zh) * 2022-07-18 2024-10-11 德商格雷斯海姆格拉斯有限責任公司 醫療容器包裝
CN117416612A (zh) * 2022-07-18 2024-01-19 格雷斯海姆玻璃有限责任公司 医疗容器包装
CN117416613A (zh) * 2022-07-18 2024-01-19 格雷斯海姆玻璃有限责任公司 医疗容器包装

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