[go: up one dir, main page]

WO2015049730A1 - Trousse d'administration de médicament - Google Patents

Trousse d'administration de médicament Download PDF

Info

Publication number
WO2015049730A1
WO2015049730A1 PCT/JP2013/076753 JP2013076753W WO2015049730A1 WO 2015049730 A1 WO2015049730 A1 WO 2015049730A1 JP 2013076753 W JP2013076753 W JP 2013076753W WO 2015049730 A1 WO2015049730 A1 WO 2015049730A1
Authority
WO
WIPO (PCT)
Prior art keywords
hollow needle
drug
container
elastic
hollow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2013/076753
Other languages
English (en)
Japanese (ja)
Inventor
幸治 福岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Creations Inc Japan
Original Assignee
Medical Creations Inc Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Creations Inc Japan filed Critical Medical Creations Inc Japan
Priority to PCT/JP2013/076753 priority Critical patent/WO2015049730A1/fr
Priority to JP2015540294A priority patent/JPWO2015049730A1/ja
Publication of WO2015049730A1 publication Critical patent/WO2015049730A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2072—Venting means for internal venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2086—Filtering means for fluid filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2058—Connecting means having multiple connecting ports
    • A61J1/2062—Connecting means having multiple connecting ports with directional valves

Definitions

  • the present invention relates to a device for transferring a drug between a syringe barrel connected in a closed system and a drug container, and the syringe cylinder after the drug transfer connected in a closed system, and an infusion bag or an infusion set.
  • the present invention relates to a technology of a closed system drug transfer system using a drug transfer kit including an apparatus for transferring a drug.
  • Dangerous drugs are drugs that are routinely used for medical purposes in medical facilities.
  • relatively high levels of mutagenic substances are detected in the urine of healthcare workers working in the environment where they are prepared and administered compared to unexposed healthcare workers, and there are concerns about adverse reproductive effects Has been.
  • a drug when a drug is leaked or dripped when a drug is sucked from a drug container into a syringe, a drug is injected into an infusion bag, or a drug is injected into an infusion set during dispensing operations.
  • the leaked drug directly touches the skin, or vaporized drug or dried drug particles float in the air and are inhaled into the body.
  • a predetermined device is used to connect the syringe barrel and the drug container as a closed system, transfer the drug between the syringe barrel and the drug container, and subsequently enclose the drug after the transfer.
  • the medicine is transferred between the syringe barrel and the infusion container or infusion set.
  • the leakage of the medicine is suppressed, and the operator / patient and the medicine
  • the operator needs long-term training when performing the operation while preventing contamination of the hospital room where the device is used.
  • the pressure difference between the inside and outside of the medicine container is eliminated using a predetermined device integrated with the medicine transporting device, but the function of equalizing the pressure inside and outside the container is unnecessary.
  • the medicine transfer device is expensive because the predetermined device is not provided.
  • a drug transfer device that transfers a drug between a syringe cylinder and a drug container that connects the syringe cylinder and the drug container in a closed system
  • a member for adjusting the detachable gas pressure is incorporated so that the closed system can be maintained, and the pressure difference between the inside and outside of the medicine container is eliminated, while the pressure difference between the inside and outside of the medicine container is eliminated.
  • a closed drug transfer kit comprising a drug transfer device for transferring a drug, a syringe after transfer of the drug connected in a closed system, and a device for transferring the drug between an infusion bag or an infusion set. Propose that.
  • One form of the disclosed medicine transfer kit includes a first member connected to the stopper side of the medicine container, a second member connected to the first member at one end, and connected to the syringe barrel at the other end.
  • a medicine transfer unit that is connected to the first member and has a third member having a variable volume for adjusting a gas pressure in the medicine container and that transfers the medicine between the medicine container and the syringe barrel.
  • the drug container and the syringe barrel having a first member connected to the stopper side of the drug container, and a second member connected to the first member at one end and connected to the syringe barrel at the other end
  • a drug transfer device that transfers the drug to and from The second member connected to the syringe containing the transferred drug, and the drug connected to the second member at one end and contained in the syringe at the other end from the syringe to the infusion container or
  • a drug transfer device comprising a fourth member for transferring into a stopcock of an infusion set and mixing with the infusion solution
  • the first member has a male part of a first fitting mechanism for connecting the first member and the second member, and the first member and the third member are When connecting, the first member further has a male part of a second fitting mechanism for connecting the first member and the third member;
  • the fourth member has a male part of a first fitting mechanism for connecting the fourth member and the second member;
  • the second member has a female portion of
  • a second hollow needle member having a hole for transferring a drug to the root part and the tip part, and a second elastic member through which the second hollow needle member can pass, and the second The tip of the hollow needle member is supported in a state of being inserted into the second elastic member
  • the first member has a first elastic member through which the second hollow needle member can penetrate and a distal end portion arranged toward the stopper side of the drug container, and toward the second member side.
  • the first hollow needle member is provided with a hole for transferring a drug at the root portion and the distal end portion, the inner diameter is larger than the outer diameter of the second hollow needle member and the root portion is disposed.
  • the first member further has a distal end portion disposed toward the stopper side of the drug container, a root portion disposed toward the third member side, and the first member passing through the root portion and the distal end portion.
  • a third hollow needle member having pores, When the hole on the base portion side of the first hollow needle member is closed by the first elastic member, and the first member and the second member are connected, the first elasticity In a state where the elastic member and the second elastic member are in contact with each other, the second hollow needle member penetrates the first elastic member and the second elastic member, and the medicine The first hollow needle member inserted through the stopper of the container is inserted, or the hole on the base portion side of the first hollow needle member is closed by the first elastic member, and the first When the first member and the second member are connected, the second hollow needle member is in the state where the first elastic member and the second elastic member are in contact with each other.
  • the fourth member has a third elastic member through which the second hollow needle member can penetrate and a distal end portion arranged toward the stopper side of the infusion container, and toward the second member side.
  • a fourth hollow needle member having a root portion and an inner diameter larger than the outer diameter of the second hollow needle member and having a hole for transferring a drug to the root portion and the tip portion; or
  • the fourth member has a third elastic member through which the second hollow needle member can penetrate and a distal end portion arranged toward the stopcock side of the infusion set, and directed toward the second member side.
  • a root portion is disposed, and has a fitting mechanism between a hollow member having an inner diameter larger than an outer diameter of the second hollow needle member and a stopcock of the infusion set, The hole on the base portion side of the fourth hollow needle member or the hollow member is closed by the third elastic member, and the second elastic member and the third elastic member are in contact with each other.
  • the second hollow needle member passes through the second elastic member and the third elastic member and is inserted into the fourth hollow needle member inserted through the stopper of the infusion container. Or inserted into the hollow member fitted to the stopcock of the infusion set, Via the fourth hollow needle member or the hollow member, and the fourth hollow needle member or the second hollow needle member inserted into the hollow member, the infusion container or the infusion set; It is characterized in that the drug is transferred between the transferred syringe containing the transferred drug.
  • one form of the disclosed medicine transfer kit is characterized in that, in addition to the above configuration, the third hollow needle member is included in the first hollow needle member.
  • the third member is a container having a bellows-like side surface.
  • one form of the disclosed medicine transfer kit includes the first hollow member between the first elastic member and the hole on the root portion side of the first hollow needle member.
  • a first filter member for preventing unwanted matter from being mixed into the needle member is provided.
  • one form of the disclosed medicine transfer kit is a second one in which the first hollow needle member prevents an unnecessary substance from being mixed into the distal end portion of the first hollow needle member.
  • the filter member is provided.
  • one form of the disclosed medicine transfer kit is a fitting between the third elastic member and a hole on the root portion side of the fourth hollow needle member or a stopcock of the hollow member Between the hole on the mechanism side, a third filter member for preventing unwanted matter from being mixed into the hollow needle member of the third elastic member or the third hollow member is further provided. To do.
  • the third hollow needle member or the third hollow member further includes a tip portion of the third hollow needle member or A fourth filter member is provided for preventing unwanted substances from being mixed into the tip of the third hollow member.
  • the first elastic member, the second elastic member, and the third elastic member are fixed by a fixing member. It is characterized by that.
  • the first member sandwiches the stopper portion of the medicine container in accordance with the outer diameter of the stopper portion of the medicine container.
  • the disclosed medicine transfer kit is characterized in that, in addition to the above configuration, the first filter member is an aspect in which a plurality of mesh-like members in which thread-like members are arranged in a mesh shape are stacked.
  • the third filter member is an aspect in which a plurality of mesh members in which thread members are arranged in a mesh shape are stacked.
  • the disclosed drug transfer kit is a closed system between the syringe barrel and the drug container, between the syringe barrel and the infusion container, and between the syringe barrel and the infusion set by an easy operation realized by adopting a simple structure.
  • Connect and transfer the drug between the syringe barrel and drug container and incorporate a member for adjusting the removable gas pressure so that the closed system can be maintained, eliminating the pressure difference inside and outside the drug container It is possible to transfer the drug between the syringe barrel and the drug container, between the syringe cylinder and the infusion container, and between the syringe cylinder and the infusion set.
  • the disclosed drug transfer kit can reduce the risk of drug leakage and dripping from drug containers, syringes, infusion containers, and infusion sets when mixing drugs.
  • the disclosed medicine transfer kit can remove the device for equalizing the pressure inside and outside the drug container, and attach the device only when it is necessary to equalize the pressure inside and outside the drug container. What is necessary is just to perform, and the operativity at the time of medicine transfer improves.
  • FIG. 1 is a diagram showing an outline of a drug transfer system 100 between a syringe barrel and a drug container including the drug transfer device 1.
  • the medicine transfer system 100 includes a medicine container 2, a first member 8, a second member 38, a third member 56, and a syringe barrel 6.
  • the medicine transfer system 100 connects the medicine container 2 and the syringe barrel 6 as a closed system using the first member 8 and the second member 38, and in the connected state, between the medicament container 2 and the syringe barrel 6. Transfer of liquid or gaseous drug.
  • the drug container 2 may be a vial as shown in FIG. 1 or may be an infusion bag as shown in FIG. 2, and a solid / liquid / gas drug is stored inside. As shown in FIG. 3, the medicine transfer device 1 can also apply the medicine container 2 as an infusion line. Moreover, the medicine container 2 is provided with a stopper 4 that is connected to other members and used when the medicine is transferred. The medicine container 2 is connected to the first member 8 on the stopper 4 side.
  • the syringe barrel 6 is also referred to as a syringe, and is a device for injecting or sucking a liquid or gaseous drug, and does not include an injection needle.
  • the syringe barrel 6 is connected to the second member 38 at the syringe barrel connecting portion 52 provided in the second member 38.
  • the first member 8 and the second member 30 are connected, and the first member 8 and the third member 56 are connected.
  • FIG. 4 is a cross-sectional view for explaining a main part of the first member 8.
  • the first member 8 includes a male part 10 of the first fitting mechanism, a first hollow needle member 12, a first elastic member 18, a first fixing member 26, and a first member.
  • the male part 10 of the first fitting mechanism is a male part of a fitting mechanism (locking mechanism) for connecting the first member 8 and the second member 38, and a second member 38 to be described later is provided.
  • the fitting mechanism is, for example, a mechanism composed of a female part having a nail shape and a male part having a shape for hanging the nail, and the nail and the part to be hooked are engaged with each other.
  • the one member 8 and the second member 38 can be easily connected and locked.
  • the fitting mechanism may have other structures.
  • the first hollow needle member 12 has a hollow needle shape inside, the distal end portion 14 is disposed toward the stopper 4 of the drug container 2, and the root portion 16 is directed toward the connection portion with the second member 38. Be placed. Further, the distal end portion 14 is inserted into the stopper 4 of the drug container 2, and the chemical solution is transferred between the drug container 2 and the syringe barrel 6. Therefore, at least the distal end portion 14 and the root portion 16 are provided with holes for drug transfer.
  • the first elastic member 18 is made of a material having elasticity such as silicon or thermoplastic resin.
  • the shape of the elastic member can be any shape including a spherical shape.
  • the first elastic member 18 is fixed at a predetermined position in the first member 8 by the first fixing member 26.
  • the predetermined position is a position where the first elastic member 18 closes the hole of the root portion 16 of the first hollow needle member 12.
  • the first fixing member 26 is a member for fixing the first elastic member 18 to a predetermined position in the first member 8 as described above.
  • the first fixing member 26 has a mortar shape with a hole in the bottom, and the first elastic member 18 is fitted into the mortar-shaped portion to thereby provide the first elasticity.
  • the member 18 is fixed at a predetermined position.
  • the shape of the first fixing member 26 is not limited to the contact and separation between the first elastic member and the second elastic member, and the hollow needle member penetrates the elastic member. As long as the first elastic member 18 can be fixed at a predetermined position, it may have a mortar shape with a hole in the bottom or a structure having other shapes.
  • the first filter member 20 penetrates the elastic members 18, 48, and the elastic member 18 generated by the second hollow needle member 42 inserted into the first hollow needle member 12, It is a member that prevents 48 scraps (hereinafter also referred to as “unnecessary items”) 54 from entering the first hollow needle member 12.
  • the first filter member 20 is disposed between the first elastic member 18 and the hole in the root portion 16 of the first hollow needle member 12.
  • FIG. 5 is a view for explaining the structure of the first filter member 20.
  • the first filter member 20 includes a mesh member 22 obtained by rotating the mesh member 22 about 45 ° to a mesh member 22 in which thread-like members are arranged in a mesh (lattice). It is a stacked configuration.
  • the first filter member 20 is a member installed for the purpose of preventing the shavings 54 of the elastic members 18 and 48 generated by the second hollow needle member 42 from entering the first hollow needle member 12. Therefore, as long as the purpose is achieved, the configuration is not limited to the above.
  • the second filter member 24 does not allow the unnecessary material 54 generated by the second hollow needle member 42 to enter the first hollow needle member 12 (particularly, the distal end portion 14). It is a member to make it.
  • the second filter member 24 is installed inside the first hollow needle member 12. The material and structure of the second filter member 24 are not limited as long as the above object is achieved.
  • FIG. 6A is a front view for explaining the main part of the drug container gripping portion 28, and FIG. 6B is a plan view for explaining the main part of the drug container gripping portion 28.
  • FIGS. 7A to 7C are views for explaining how the size of the medicine container gripping portion 28 is changed in accordance with the stoppers 4 of various sizes.
  • the size of the stopper 4 of the drug container 2 is various such as a diameter of 15 mm, 20 mm, 30 mm. Accordingly, as shown in FIG. 6A, the drug container gripping portion 28 fixes the connection relationship between the drug container 2 and the first member 8 by sandwiching the stopper 4 or neck portion of the drug container 2 from the side. It is a member to do. Further, as shown in FIG. 6 (b), the drug container gripping portion 28 can be connected to the plug 4 (or neck portion) of the drug container 2 in accordance with the size of the connection site. .
  • medicine container grasping part 28 shall adjust the size of a connection part to the size of stopper 4 (or neck part) of medicine container 2,
  • the connection relationship between the drug container 2 and the first member 8 is fixed by sandwiching the plug 4 (or neck portion) from both the left and right sides or the four sides.
  • the drug container gripping portion 28 is elastic so that the outer diameter of the set connection portion changes in accordance with the size of the outer diameter of the plug portion of the drug container and stably holds the plug portion of the drug container. It can be made into the member made from the raw material which has.
  • the third hollow needle member 32 has a hollow needle shape inside, the distal end portion 34 of the third hollow needle member is arranged toward the stopper 4 of the drug container 2, and the root portion of the third hollow needle member 36 is arranged toward the connection portion with the third member 56.
  • the third member 56 is a member for keeping the pressure in the drug container 2 constant (making the pressure inside and outside the drug container 2 uniform).
  • the drug solution is transferred between the drug container 2 and the syringe barrel 6 with the distal end portion 34 of the third hollow needle member inserted into the stopper 4 of the drug container 2, at least the third hollow needle is used.
  • the distal end portion 34 of the member and the root portion 36 of the third hollow needle member are provided with holes through which the gas in the drug container 2 moves.
  • the male part 30 of the second fitting mechanism is a male part of a fitting mechanism (locking mechanism) for connecting the first member 8 and the third member 56, and a third member 56 described later is provided.
  • the second fitting mechanism is, for example, a mechanism that includes a female part that has a claw shape and a male part that has a shape that hangs the claw, and the claw and the part that hangs the claw are engaged with each other.
  • the first member 8 and the third member 56 can be easily connected and locked.
  • the second fitting mechanism may have other structures.
  • the male part 30 of the second fitting mechanism is disposed at the root part 36 of the third hollow needle member 32. Then, as shown in FIG. 4, the male part 30 (the root part 36 of the third hollow needle member 32) of the second fitting mechanism does not connect the first member 8 and the third member 56. In order to prevent the medicine in the medicine container 2 from leaking out, the hole can be closed by the stopper 64.
  • the 3rd hollow needle member 32 may be a form (included in the 1st hollow needle member 12) which shares the front-end
  • the form provided separately from the 1st hollow needle member 12 may be sufficient.
  • FIG. 8 is a cross-sectional view for explaining a main part of the second member 38.
  • the second member 38 includes a syringe barrel connection portion 52, a first fitting mechanism female portion 40, a second hollow needle member 42, a second elastic member 48, and a second elastic member 48.
  • a fixing member 50 is provided.
  • the syringe barrel connection portion 52 is a portion connected to the syringe barrel 6 in which the liquid or gaseous medicine to be transferred is stored, and is located at the other end of the portion to which the first member 8 is connected. There is no particular limitation regarding the mechanism for connecting the syringe barrel connection portion 52 and the syringe barrel 6.
  • the female portion 40 of the first fitting mechanism is a female portion of a fitting mechanism (lock mechanism) for connecting the first member 8 and the second member 38, and the first member 8 includes a first portion.
  • the fitting mechanism is, for example, a mechanism composed of a female part having a nail shape and a male part having a shape for hanging the nail, and the nail and the part to be hooked are engaged with each other.
  • the one member 8 and the second member 38 can be easily connected and locked.
  • the fitting mechanism may have other structures.
  • the second hollow needle member 42 has a hollow needle shape inside, the distal end portion 44 is disposed toward the first member 8 (first hollow needle portion 12), and the root portion 46 is connected to the syringe barrel 6. It arrange
  • the distal end portion 44 is supported while being inserted into a second elastic member 48 described later, and the root portion 46 is fixed to the syringe barrel connection portion 52.
  • the first member 8 and the second member 38 are connected when the medicine is transferred, and the second hollow needle member 42 is inserted into the first hollow needle member 12. Therefore, the direction of the second hollow needle member 42 is fixed in a predetermined direction, and the connection operation between the members 8 and 38 (insertion operation of the hollow needle members 12 and 42) can be performed reliably and easily.
  • the drug solution is transferred between the drug container 2 and the syringe barrel 6 via the second hollow needle member 42, at least the tip 44 and the root 46 are provided with holes for drug transfer.
  • the second elastic member 48 is made of a material having elasticity such as silicon or thermoplastic resin.
  • the shape of the elastic member can be any shape including a spherical shape.
  • the second elastic member 48 is fixed at a predetermined position in the second member 38 by the second fixing member 50.
  • the predetermined position means that when the first member 8 and the second member 38 are connected, the first elastic member 18 and the second elastic member 48 are applied with a predetermined force. It is a position to touch.
  • the second fixing member 50 is a member for fixing the second elastic member 48 at a predetermined position in the second member 38 as described above.
  • the second fixing member 50 has a mortar shape with a hole in the bottom, and a second elastic member 48 having a spherical shape is fitted into the mortar-shaped portion, thereby providing a second elasticity.
  • the member 48 is fixed at a predetermined position.
  • the shape of the second fixing member 50 is such that the second elastic member, the first elastic member and the third elastic member are brought into contact with and separated from each other, and the elastic member is hollow. As long as the first elastic member 18 can be fixed at a predetermined position even if the needle member is penetrated, it has other shapes even if it has a mortar shape with a hole in the bottom. It may be structured.
  • FIGS. 9 and 10 are cross-sectional views for explaining a connection mode of the first member 8 and the second member 38.
  • the male part 10 of the first fitting mechanism and the female of the first fitting mechanism for connecting the first member 8 and the second member 38 are used.
  • the part 40 is fitted and the 1st member 8 and the 2nd member 38 are connected.
  • the first elastic member 18 and the second elastic member 48 come into contact with each other, and the contact portions of the elastic members 18 and 48 are crushed, and the first member 8 and the second elastic member 48 are brought into contact with each other.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the distal end portion 44 of the second hollow needle member 42 supported by the second elastic member 48 is moved to the second procedure while maintaining the above state.
  • the first elastic member 48 and the first elastic member 18 are pushed and penetrated through the first hollow needle member 12 through the root portion 16.
  • the second hollow needle member 42 may scrape the elastic members 18 and 48, the first filter member 20 and the second filter member 24 prevent permeation of the shavings 54.
  • the third member 56 includes a female portion 58 of the second fitting mechanism and a container pressure adjusting member 60.
  • the female portion 58 of the second fitting mechanism is a female portion of a fitting mechanism (lock mechanism) for connecting the first member 8 and the third member 56, and the first member 8 includes a first portion.
  • the second fitting mechanism is, for example, a mechanism that includes a female part that has a claw shape and a male part that has a shape that hangs the claw, and the claw and the part that hangs the claw are engaged with each other.
  • the first member 8 and the third member 56 can be easily connected and locked.
  • the second fitting mechanism may have other structures.
  • the female portion 58 of the second fitting mechanism is disposed around the opening 62 of the container pressure adjusting member 60. As shown in FIG. 11, the female portion 58 (the opening 62 of the container pressure adjusting member 68) of the second fitting mechanism is plugged when the first member 8 and the third member 56 are not connected. It is also possible to close the hole by 64.
  • the container pressure adjusting member 60 serves as a gas flow path in the medicine container 2, but the medicine in the medicine container 2 may flow in.
  • the container pressure adjusting member 60 changes its volume by the expansion and contraction of the bellows when the gas in the communicating medicine container 2 flows in. As a result, the pressure in the communicating medicine container 2 is made uniform with the external pressure. It is a member to be converted.
  • the container pressure adjusting member 60 communicates with the drug container 2 via the female portion 58 of the second fitting mechanism provided at the end portion.
  • the container pressure adjusting member 60 may be a container having a bellows-like side surface, and its volume may be changed by expanding or contracting the bellows-shaped part.
  • the container pressure adjusting member 60 is a soft bag-like container having a tube member therein, and may be wound around the tube member when not in use, or may have other shapes. .
  • FIG. 13 is a diagram showing an outline of a drug transfer system 200 using a drug transfer device between a syringe barrel and an infusion container constituting the drug transfer kit according to the present embodiment.
  • the drug transfer system between the syringe barrel and the infusion container includes an infusion container 76, a second member 38, a fourth member 78, and the syringe barrel 6.
  • the drug transfer system 200 connects the infusion container 76 and the syringe barrel 6 as a closed system using the second member 38 and the fourth member 78, and in the connected state, between the infusion container 76 and the syringe barrel 6. Transfer of liquid or gaseous drugs.
  • the infusion container 76 may be an infusion bag or a vial, and a solid, liquid, or gas medicine is stored therein.
  • the infusion container 76 is connected to the fourth member 78 on the stopper 90 side.
  • the syringe barrel 6 is connected to the second member 38 at the syringe barrel connecting portion 52 provided in the second member 38.
  • the second member 38 and the fourth member 78 are connected.
  • the fourth member 78 includes the male portion 10 of the first fitting mechanism, the fourth hollow needle member 80, the third elastic member 82, and the third fixing member. 84.
  • the fourth hollow needle member 80 may have a linear shape, bend at the center, and have a shape that is L-shaped when viewed from the side, for example, as shown in FIGS. It is good as a thing.
  • the male part 10 of the first fitting mechanism provided in the fourth member is a male part of a fitting mechanism (locking mechanism) for connecting the fourth member 78 and the second member 38,
  • the fourth member 78 and the second member 38 are connected by a simple operation by fitting into the female portion 40 included in the second member 38.
  • the fitting mechanism is, for example, a mechanism composed of a female part having a nail shape and a male part having a shape for hanging the nail, and the nail and the part to be hooked are engaged with each other.
  • the four members 8 and the second member 38 can be easily connected and locked.
  • the fitting mechanism may have other structures.
  • the fourth hollow needle member 80 has a hollow needle shape inside, the distal end portion 96 is disposed toward the stopper 90 of the infusion container 76, and the root portion 94 is directed toward the connection portion with the second member 38. Be placed. Further, the distal end portion 96 is inserted into the stopper 90 of the infusion container 76, and the chemical solution is transferred between the infusion container 76 and the syringe barrel 6. Therefore, at least the distal end portion 96 and the root portion 94 are provided with holes for transferring medicine.
  • the third elastic member 82 is made of, for example, a material having elasticity such as silicon or thermoplastic resin.
  • the shape of the elastic member can be any shape including a spherical shape.
  • the third elastic member 82 is fixed at a predetermined position in the fourth member 78 by the third fixing member 84.
  • the predetermined position is a position where the third elastic member 82 closes the hole of the root portion 94 of the fourth hollow needle member 92.
  • the third fixing member 84 is a member for fixing the third elastic member 82 to a predetermined position in the fourth member 78 as described above.
  • the third fixing member 84 has a mortar shape with a hole in the bottom, and a third elastic member 82 is fitted into the mortar-shaped portion to thereby provide a third elasticity.
  • the member 82 is fixed at a predetermined position.
  • the fourth member may further include a third filter member 86 and a fourth filter member 88. Thereby, it is possible to prevent the unnecessary material derived from the fixing member caused by the penetration of the second hollow needle member from being mixed into the infusion container.
  • the third filter member 86 is obtained by superposing a mesh member obtained by rotating the mesh member about 45 ° on a mesh member in which thread-like members are arranged in a mesh shape (lattice shape). It is a configuration.
  • the third filter member 86 is a member that is installed for the purpose of preventing unwanted materials, which are shavings of the elastic member generated by the hollow needle member, from entering the hollow needle member. As long as it does, it is not limited to the said structure.
  • the fourth filter member 88 is a member that prevents unwanted matter generated by the second hollow needle member from entering the fourth hollow needle member (particularly at the tip). is there.
  • the fourth filter member 88 is installed inside the fourth hollow needle member 92.
  • a material and a structure are not limited.
  • FIGS. 15 and 16 are cross-sectional views for explaining a connection mode of the fourth member 78 and the second member 38.
  • the male part 10 of the first fitting mechanism and the female part of the first fitting mechanism for connecting the fourth member 78 and the second member 38 are used.
  • the parts 40 are fitted together, and the fourth member 78 and the second member 38 are connected.
  • the third elastic member 82 and the second elastic member 48 come into contact with each other, and the portions where the elastic members 82 and 48 come into contact with each other are crushed.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the distal end portion 44 of the second hollow needle member 42 supported by the second elastic member 48 is moved in the second state while the above state is continued.
  • the elastic member 48 and the third elastic member 82 are pushed through and penetrated through the fourth hollow needle member 92 from the root portion 94.
  • the second hollow needle member 42 may scrape the elastic members 82 and 48, the third filter member 86 and the fourth filter member 88 transmit the unnecessary material 54 as shavings. To prevent.
  • the distal end portion 96 of the fourth hollow needle member 92 is inserted into the stopper 90 of the infusion container 76, and the chemical solution is transferred between the infusion container 76 and the syringe barrel 6 through the hollow needle members 92 and 42. .
  • FIG. 14 is a diagram showing an outline of a drug transfer system 200 using a drug transfer device between a syringe barrel and an infusion container constituting the drug transfer kit according to the present embodiment.
  • the drug transfer system between the syringe barrel and the infusion set includes an infusion set 106, a second member 38, a fourth member 78, and the syringe barrel 6.
  • the drug transfer system 200 connects the infusion set 106 and the syringe barrel 6 as a closed system using the second member 38 and the fourth member 78, and in the connected state, between the infusion set 106 and the syringe barrel 6. Transfer of liquid or gaseous drugs.
  • the infusion set 106 includes a bottle needle 108, a tube 110, a drip tube 112, a stopcock 114, a clamp 118, and the like, and is connected to the infusion container 76 in a closed system by the bottle needle 108.
  • the stopcock 114 a three-way stopcock is preferably used.
  • the infusion container 76 may be an infusion bag or a vial (Vial), in which a medicine is stored.
  • the infusion set 106 is connected to the fourth member 78 at the connection part 116 of the stopcock 114.
  • the syringe barrel 6 is connected to the second member 38 at the syringe barrel connecting portion 52 provided in the second member 38.
  • the second member 38 and the fourth member 78 are connected.
  • the fourth member 78 in the drug transfer device between the syringe barrel 6 and the infusion set 106 will be described. As shown in FIGS. 14, 17, and 18, the fourth member 78 includes the male part 10 of the first fitting mechanism, the fourth hollow member 98, the third elastic member 82, and the third fixing member 84.
  • the male part 10 of the first fitting mechanism provided in the fourth member is a male part of a fitting mechanism (locking mechanism) for connecting the fourth member 78 and the second member 38,
  • the fourth member 78 and the second member 38 are connected by a simple operation by fitting into the female portion 40 included in the second member 38.
  • the fitting mechanism is, for example, a mechanism composed of a female part having a nail shape and a male part having a shape for hanging the nail, and the nail and the part to be hooked are engaged with each other.
  • the four members 8 and the second member 38 can be easily connected and locked.
  • the fitting mechanism may have other structures.
  • the fourth hollow member 98 has a hollow inside, the distal end portion 104 is disposed toward the connection portion 116 of the stopcock 114 of the infusion set 106, and the root portion 102 is directed toward the connection portion with the second member 38. Be placed. Moreover, the front-end
  • the third elastic member 82 is made of, for example, a material having elasticity such as silicon or thermoplastic resin.
  • the shape of the elastic member can be any shape including a spherical shape.
  • the third elastic member 82 is fixed at a predetermined position in the fourth member 78 by the third fixing member 84.
  • the predetermined position is a position where the third elastic member 82 closes the hollow hole of the root portion 102 of the fourth hollow member 98.
  • the third fixing member 84 is a member for fixing the third elastic member 82 to a predetermined position in the fourth member 78 as described above.
  • the third fixing member 84 has a mortar shape with a hole in the bottom, and a third elastic member 82 is fitted into the mortar-shaped portion to thereby provide a third elasticity.
  • the member 82 is fixed at a predetermined position.
  • the fourth member may further include a third filter member 86 and a fourth filter member 88. Thereby, it is possible to prevent the unnecessary material derived from the fixing member caused by the penetration of the second hollow needle member from being mixed into the infusion set.
  • the third filter member 86 is obtained by superposing a mesh member obtained by rotating the mesh member about 45 ° on a mesh member in which thread-like members are arranged in a mesh shape (lattice shape). It is a configuration.
  • the third filter member 86 is a member that is installed for the purpose of preventing unwanted materials, which are shavings of the elastic member generated by the hollow needle member, from entering the hollow member, the third filter member 86 achieves that purpose. As long as it is not limited to the above configuration.
  • the fourth filter member 88 is a member that prevents unwanted matter generated by the second hollow needle member from entering the fourth hollow needle member (particularly at the tip). is there.
  • the fourth filter member 88 is installed inside the fourth hollow member 98.
  • a material and a structure are not limited.
  • connection form of the fourth member 78 and the second member 38 will be described with reference to FIGS. 17 and 18.
  • 17 and 18 are cross-sectional views for explaining a connection mode of the fourth member 78 and the second member 38.
  • the male part 10 of the first fitting mechanism and the female part of the first fitting mechanism for connecting the fourth member 78 and the second member 38 are used.
  • the parts 40 are fitted together, and the fourth member 78 and the second member 38 are connected.
  • the third elastic member 82 and the second elastic member 48 come into contact with each other, and the portions where the elastic members 82 and 48 come into contact with each other are crushed.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the distal end portion 44 of the second hollow needle member 42 supported by the second elastic member 48 is kept in the second state while maintaining the above state.
  • the elastic member 48 and the third elastic member 82 are pushed through and penetrated from the root portion 102 into the fourth hollow member 98.
  • the second hollow needle member 42 may scrape the elastic members 82 and 48, the third filter member 86 and the fourth filter member 88 transmit the unnecessary material 54 as shavings. To prevent.
  • tip part 104 of the 4th hollow member 98 is inserted in the connection part 116 of the stopcock 114 of the infusion set 106, and the female part 120 of the fitting mechanism with which the front-end
  • the male part 122 of the fitting mechanism provided at the distal end of the connection part 116 of the stopcock 114 of the infusion set, and the drug solution is transferred between the infusion set 106 and the syringe barrel 6 by the hollow member 98 and the hollow needle member 42. It is carried out in a closed system via
  • the method of using the drug transfer device 1 constituting the drug transfer kit of the present invention specifically, the drug transfer device A method of transferring a drug between the drug container 2 and the syringe barrel 6 in the drug transfer system 100 including 1 will be described.
  • drug transfer when the drug container 2 is a vial and drug transfer when the drug container 2 is an infusion bag as shown in FIG. 2 are assumed. .
  • the operator inserts the distal end portion 14 of the first hollow needle member 12 included in the first member 8 shown in FIG. 2 and the first member 8 are connected.
  • the operator adjusts the size of the drug container gripping portion 28 in accordance with the size of the diameter of the plug portion 4 of the drug container 2, and the plug portion
  • the connection relationship between the drug container 2 and the first member 8 is fixed by sandwiching from the left and right sides or four sides of 4 (or the neck portion).
  • the operator fits the male part 10 of the first fitting mechanism and the female part 40 of the first fitting mechanism together with the first member 8.
  • the second member 38 is connected.
  • the first elastic member 18 and the second elastic member 48 come into contact with each other, and the contact portions of the elastic members 18 and 48 are crushed, and the first member 8 and the second elastic member 48 are brought into contact with each other.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the operator As the fourth procedure, the operator, as shown in FIG. 10, maintains the state where the third procedure is completed, and the second hollow needle member supported by the second elastic member 48.
  • the distal end portion 44 of 42 is pushed and penetrated in the second elastic member 48 and the first elastic member 18. Further, the operator inserts the second hollow needle member 42 into the first hollow needle member 12 from the root portion 16. At this time, since the second hollow needle member 42 may scrape the elastic members 18 and 48, the first filter member 20 and the second filter member 24 prevent permeation of the shavings 54.
  • the operator connects the syringe barrel 6 to the syringe barrel connecting portion 52 provided in the second member 38 as shown in FIG. 1 or FIG.
  • the operator transfers the drug from the syringe barrel 6 toward the drug container 2 or from the drug container 2 toward the syringe barrel 6. At that time, the operator transfers the medicine by inverting the medicine container 2 or appropriately operating the syringe barrel 6. (2) Pressure equalization in the drug container
  • FIGS. 1, 2, and 10 to 12 a method of using the drug transfer device 1, that is, a method of pressure equalizing operation in the drug container 2 in the drug transfer system 100 including the drug transfer device 1 is described.
  • drug transfer when the drug container 2 is a vial and drug transfer when the drug container 2 is an infusion bag as shown in FIG. 2 are assumed.
  • the operator connects the first member 8 shown in FIG. 10 and the third member 56 shown in FIG. 11 to obtain the state of the medicine transfer device 1 shown in FIG. Specifically, the male part 30 of the second fitting mechanism provided in the first member 8 and the female part 58 of the second fitting mechanism provided in the third member 56 are fitted together, and the first member 8 is fitted. And the third member 56 are connected.
  • the operator uses the medicine transfer device 1 to which the first member 8, the second member 38, and the third member 56 are connected.
  • the gas or liquid (drug, air, diluent, etc.) is transferred from the drug container 2 to the drug container 2 and mixed with the drug in the drug container 2.
  • the gas (air) flows from the inside of the medicine container 2 into the container pressure adjusting member 60 via the third hollow needle member 32, and inside the medicine container 2. Is negative pressure, the gas (air) flows from the container pressure adjusting member 60 into the drug container 2 via the third hollow needle member 32.
  • the pressure inside the medicine container 2 becomes substantially equal to the pressure outside the medicine container 2, and the risk of leakage or dripping of dangerous medicine from the stopper 4 of the medicine container 2 is reduced.
  • the container pressure adjusting member 60 is a container having a bellows side surface
  • the gas (air) in the drug container 2 flows into the container having a bellows side surface via the third hollow needle member 32.
  • the bellows part on the side of the container expands.
  • the gas (air) in the container whose side surface is bellows flows into the drug container 2 through the third hollow needle member 32, the bellows portion on the side surface of the container contracts.
  • the method of using the drug transfer device between the syringe barrel and the infusion container constituting the drug transport kit of the present invention specifically, the drug transfer between the syringe barrel and the infusion container
  • a method for transferring a drug between the syringe barrel 6 and the infusion container 76 in the drug transfer system 200 including the apparatus will be described.
  • the operator inserts the distal end portion 96 of the fourth hollow needle member 92 included in the fourth member 78 shown in FIGS. 13 and 15 into the plug portion 90 of the infusion container 76.
  • the infusion container 76 and the fourth member 78 are connected.
  • the operator fits the male part 10 of the first fitting mechanism and the female part 40 of the first fitting mechanism,
  • the syringe barrel 6 containing the medicine transferred in the item (1) is connected to the second member 38 connected to the syringe barrel connecting portion 52.
  • the third elastic member 82 and the second elastic member 48 come into contact with each other, and the portions where the elastic members 82 and 48 come into contact with each other are crushed.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the operator As the third procedure, the operator, as shown in FIG. 16, maintains the state where the second procedure is completed, and the second hollow needle member supported by the second elastic member 48.
  • the distal end portion 44 of 42 is pushed forward in the second elastic member 48 and the third elastic member 82 and penetrated while maintaining a closed system. Further, the operator inserts the second hollow needle member 42 into the fourth hollow needle member 92 from the root portion 94. At this time, since the second hollow needle member 42 may scrape the elastic members 48 and 82, the third filter member 86 and the fourth filter member 88 transmit the unnecessary material 54 as shavings. May be prevented.
  • the method for using the drug transfer device between the syringe barrel and the infusion set which constitutes the drug transfer kit of the present invention, specifically, the drug transfer between the syringe barrel and the infusion set.
  • a method of transferring a drug between the syringe barrel 6 and the infusion container 106 in the drug transfer system 200 including the apparatus will be described.
  • the operator inserts the distal end portion 104 of the fourth hollow member 98 included in the fourth member 78 shown in FIGS. 14 and 17 into the connection portion 116 of the stopcock 114 of the infusion set 106.
  • the infusion set 106 and the fourth member 78 are connected by being fitted by the female part 120 of the fitting mechanism of the fourth hollow member and the male part 122 of the fitting mechanism in the connecting part of the stopcock.
  • the operator fits the male part 10 of the first fitting mechanism and the female part 40 of the first fitting mechanism,
  • the syringe barrel 6 containing the medicine transferred in the item (1) is connected to the second member 38 connected to the syringe barrel connecting portion 52.
  • the third elastic member 82 and the second elastic member 48 come into contact with each other, and the portions where the elastic members 82 and 48 come into contact with each other are crushed.
  • the connection part with the member 38 becomes a closed system closed from the outside.
  • the operator As the third procedure, the operator, as shown in FIG. 18, maintains the state where the second procedure is completed, and the second hollow needle member supported by the second elastic member 48.
  • the distal end portion 44 of 42 is pushed forward in the second elastic member 48 and the third elastic member 82 and penetrated while maintaining a closed system. Further, the operator inserts the second hollow needle member 42 into the fourth hollow member 98 from the root portion 102.
  • the second hollow needle member 42 may scrape the elastic members 48 and 82, the fourth filter member 86 and the fourth filter member 88 are further added to the fourth member. It may be provided, and it may be made to suppress that unnecessary material 54 which is shavings mixes by those filter members.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention includes the male part 10 of the fitting mechanism provided in the first member 8 and the female part 40 of the first fitting mechanism provided in the second member 38.
  • the first member 8 and the second member 38 can be reliably and easily connected.
  • the distal end portion 44 of the second hollow needle member is supported in a state of being inserted into the second elastic member 48, and the second hollow needle member Since the root portion 46 is fixed to the syringe barrel connection portion 52, the direction of the second hollow needle member 42 is fixed in a predetermined direction, so that the connection operation between the members 8 and 38 can be performed reliably and easily. Can do.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention is a closed system in which the connecting portions of the members 8 and 38 are closed from the outside by bringing the contacted portions of the elastic members 18 and 48 into a crushed state. And The medicine transfer device 1 allows the second hollow needle member 42 to be inserted into the first hollow needle member 12 through the closed system, and the medicine container 2. Since the medicine is transferred between the syringe barrels 6, leakage and dripping of the medicine do not occur. The medicine transfer device 1 installs the first filter member 20 and the second filter member 24 to strongly prevent the unnecessary material 54 as shavings from being mixed into the medicine container 2.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention includes the drug container gripping portion 28, thereby fixing and connecting the first member 8 to the drug containers 2 of various sizes. Therefore, it is possible to transfer medicines in a closed system with respect to various medicine containers 2.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention is configured to equalize the pressure inside and outside the drug container 2 by the third member 56, so that the drug from the drug container 2 at the time of drug mixing or the like can be obtained. The risk of leakage and dripping can be reduced.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention can remove the third member 56 for equalizing the pressure inside and outside the drug container 2. Therefore, the medicine transfer device 1 may be attached to the third member 56 only when it is necessary to equalize the pressure inside and outside the medicine container 2, and the operability during medicine transfer is improved.
  • the drug transfer device 1 constituting the drug transfer kit of the present invention can remove the third member 56 for equalizing the pressure inside and outside the drug container 2.
  • the medicine transfer device 1 that does not include the instrument 56 may be manufactured and sold, and the selling price can be reduced by reducing the manufacturing cost.
  • the drug transfer device between the syringe barrel / infusion container or the syringe barrel / infusion set constituting the drug transfer kit of the present invention includes the male part 10 and the second member 38 of the fitting mechanism provided in the fourth member 78.
  • the fourth member 78 and the second member 38 can be reliably and easily connected.
  • the distal end portion 44 of the second hollow needle member is inserted into the second elastic member 48. Since the root portion 46 of the second hollow needle member is fixed to the syringe barrel connection portion 52 and the orientation of the second hollow needle member 42 is fixed in a predetermined direction, the member 78, The connection operation between 38 can be performed reliably and easily.
  • the drug transfer device between the syringe barrel / infusion container or the syringe barrel / infusion set constituting the drug transfer kit of the present invention is configured such that the member 78, The connection part of 38 is a closed system closed from the outside.
  • the medicine transfer device allows the second hollow needle member 42 to be inserted into the fourth hollow needle member 92 or the fourth hollow member 98 via the closed system, and the hollow needle members 92, 42 are inserted.
  • No leakage or dripping In order to transfer the drug between the infusion container 76 and the syringe barrel 6 via the or to transfer the drug between the infusion set 106 and the syringe barrel 6 via the hollow member 98 and the hollow needle member 42, No leakage or dripping.
  • the medicine transfer device strongly prevents the unnecessary material 54 as shavings from being mixed into the medicine container 2 by installing the third filter member 86 and the fourth filter member 88.
  • the drug transfer kit of the present invention includes the drug transfer device 1 and the drug transfer device between the syringe barrel / infusion container or the syringe barrel / infusion set, thereby ensuring that each device is maintained while maintaining a closed system. It is possible to connect and disconnect easily, and it is possible to reliably transfer the drug from the drug container to the inside of the infusion container or infusion set containing the infusion for delivery to the patient. While improving significantly, the risk of a chemical

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention concerne une trousse d'administration de médicament, qui relie un tube de seringue à un récipient de médicament à l'aide d'un système de fermeture au moyen d'une opération facile qui peut être réalisée à l'aide d'une configuration simple, règle la pression de gaz dans le récipient de médicament au niveau du système de fermeture au moyen d'un troisième élément à volume variable relié à un premier élément, et administre un médicament entre le tube de seringue et le récipient de médicament par l'intermédiaire d'un premier élément d'aiguille creuse et d'un deuxième élément d'aiguille creuse dans le système de fermeture. De plus, la trousse d'administration de médicament relie le tube de seringue, dans lequel a été administré le médicament, à un récipient de solution de perfusion ou un ensemble de solution de perfusion au niveau du système de fermeture, et administre le médicament entre le tube de seringue et le récipient de solution de perfusion ou l'ensemble de solution de perfusion dans le système de fermeture par l'intermédiaire du premier élément d'aiguille creuse et d'un quatrième élément d'aiguille creuse ou d'un élément creux dans le système de fermeture. Les premier à quatrième éléments sont reliés facilement et de façon fiable au moyen d'un mécanisme de raccordement, et les éléments d'aiguille creuse mentionnés ci-dessus pénètrent dans les éléments élastiques de chaque élément tandis que lesdits éléments élastiques sont reliés l'un à l'autre et s'appuient l'un contre l'autre, et les éléments d'aiguille creuse sont introduits dans les éléments d'aiguille creuse ou l'élément creux.
PCT/JP2013/076753 2013-10-01 2013-10-01 Trousse d'administration de médicament Ceased WO2015049730A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/JP2013/076753 WO2015049730A1 (fr) 2013-10-01 2013-10-01 Trousse d'administration de médicament
JP2015540294A JPWO2015049730A1 (ja) 2013-10-01 2013-10-01 薬剤移送キット

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2013/076753 WO2015049730A1 (fr) 2013-10-01 2013-10-01 Trousse d'administration de médicament

Publications (1)

Publication Number Publication Date
WO2015049730A1 true WO2015049730A1 (fr) 2015-04-09

Family

ID=52778344

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/076753 Ceased WO2015049730A1 (fr) 2013-10-01 2013-10-01 Trousse d'administration de médicament

Country Status (2)

Country Link
JP (1) JPWO2015049730A1 (fr)
WO (1) WO2015049730A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020165469A1 (fr) * 2019-02-11 2020-08-20 Vidal Lopez Carlos Francisco Dispositif pour la trituration et la dissolution/suspension de médicaments dangereux à administration par voie entérale

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008006066A (ja) * 2006-06-29 2008-01-17 Shinko Chemical Co Ltd 輸液の調製用デバイス
JP2010524626A (ja) * 2007-04-23 2010-07-22 プラストメッド リミテッド 有害薬剤を汚染なく移送するための方法及び装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008006066A (ja) * 2006-06-29 2008-01-17 Shinko Chemical Co Ltd 輸液の調製用デバイス
JP2010524626A (ja) * 2007-04-23 2010-07-22 プラストメッド リミテッド 有害薬剤を汚染なく移送するための方法及び装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020165469A1 (fr) * 2019-02-11 2020-08-20 Vidal Lopez Carlos Francisco Dispositif pour la trituration et la dissolution/suspension de médicaments dangereux à administration par voie entérale

Also Published As

Publication number Publication date
JPWO2015049730A1 (ja) 2017-03-09

Similar Documents

Publication Publication Date Title
JP5510985B2 (ja) 薬剤移送装置
US11690788B2 (en) System for closed transfer of fluids
JP5510986B2 (ja) 薬剤移送装置
AU2016276956B2 (en) Syringe adapter with spinning connector
US20150290079A1 (en) Drug container storage device, drug container storage system, and method for sucking drug
US9999570B2 (en) Fluid transfer device and packaging therefor
JP6783838B2 (ja) 流体移送器具
JP2010521219A (ja) 穿刺部材保護装置
WO2015049730A1 (fr) Trousse d'administration de médicament
WO2015049729A1 (fr) Dispositif d'administration de médicament
WO2013150578A1 (fr) Dispositif d'administration de médicament
WO2013150580A1 (fr) Dispositif d'administration de médicament
WO2013150577A1 (fr) Dispositif d'administration de médicament

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13895032

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2015540294

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205 DATED 30.06.2016)

122 Ep: pct application non-entry in european phase

Ref document number: 13895032

Country of ref document: EP

Kind code of ref document: A1