WO2014189478A2

WO2014189478A2 - Ear cleaning mixture appliable as foam or in shampoo form

Info

Publication number: WO2014189478A2
Application number: PCT/TR2014/000178
Authority: WO
Inventors: Umut KAPAR; Sinem KAPAR; Ibrahim ALTOPARLAK
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-05-23
Filing date: 2014-05-22
Publication date: 2014-11-27
Anticipated expiration: 2015-11-23
Also published as: WO2014189478A3

Abstract

The invention is an ear cleaning mixture for cleaning the ear, external ear canal and earwax forming in external ear canal, wherein; it is a mixture in foam form consisting of one or more active ingredients with ceruminolytic feature consisting of docusate sodium, triethanolamine polypeptide oleate condensate and carbamide peroxide; solvents; surfactants and auxiliary surfactants with cleaning and foaming feature; foam enhancing agents; viscosity enhancing agents; conditioners; hydrophilic emollients; moisturizers that exhibit humectant features and avoid drying on skin; protective materials protecting the product from microbial contamination; pH regulator regulating product's pH; and re-oily; aromatizing agents and emollients with softening features.

Description

DESCRIPTION

EAR CLEANING MIXTURE APPLIABLE AS FOAM OR IN SHAMPOO FORM

Technical Field:

The invention relates to foam or shampoo formulation that can be used for cleaning the earlap, external ear canal, and the earwax forming in external ear canal.

Background Art:

At the entrance of the external ear canal where hair is existent, an ocher or fawn colored natural secretion called as "cerumen" is formed by particular sebaceous glands that are located in the skin. This has features like protecting and lubricating the ear canal and avoiding the microbes.

Being a secretion of the external ear canal, the cerumen is produced by the sebaceous glands located in skin of external ear canal. The object thereof is to protect the external ear canal against infections. Normally, cerumen is passed in direction of earlap through external ear canal by the self- grooming function of the skin, but sometimes, it is secreted too much, gets stiff, or the cerumen cleaning function is damaged by applications like cotton swabs and it cannot be removed. Excessive cerumen (earwax) accumulating in the external ear canal cause hearing impairment, tinnitus or earache and dizziness.

Due to the form of ear canals, cleaning is difficult. Within the state of art, the present methods used for cleaning external ear canals can be collected under two main titles. The first one is the personal cleaning stuff that can be used for the user to clean his/her ears, and the other one is the professional cleaning stuff that can be used by doctors or specialized persons for professional purposes.

The most common example of personal cleaning stuff is the cotton buds and similar elements. Yet, due to the structure of ears, it is inconvenient to insert such things as cotton buds or other materials into the ear. During the use of cotton buds for cleaning ear canals, the hair, which is one of most vital element for the cleaning function in the ear may get damaged and become nonfunctional. Cerumen present in the ear canal is actually a secretion that has features such as protecting and lubricating the ear canal, and avoiding microbes. Furthermore, the cerumen prevents the dust and particles coming from external sources from reaching inner parts. This secretion is carried by the hair existent on the ear canal and thrown out of the body. Cleaning of the ear canal using hard objects, even though there exist flexible materials at their tips, damages the movement of the hair in canals. In this case, the discharging mechanism that functions naturally in the ears gets damaged and the external ear canal can be blocked.

On the other hand, while cleaning the interior of the ear using hard materials like cotton buds, the dirt is moved further into the ear canal by the pressure applied externally, and after consecutive cleanings, there may exist accumulations in some parts of the ear canal. Due to these accumulations, external ear canals can be blocked.

During ear cleaning, a hard object is inserted into the ear canal using hard materials like cotton buds and the canal is cleaned by radial moves. As a result of wrong cleaning, there are possibilities that a user can contact the tympanic membranes located at the end of the ear canal and damage them. On the other hand, the action of the cotton buds inside awakes the nerve ending in corresponding area and causes more cerumen to be produced, and the cerumen to be pushed backwards and thus, to be sticked to the tympanic membrane.

Another example for ear cleaning is the ear candle. According to this method, an easily melting funnel is propped against the ear and end of said funnel is burned for creating a vacuum effect. Vacuum of pipe by the fire takes the collected earwax in the ear out. This method is not applicable by a person on his/her own. Yet, it is dangerous as it is applied by burning candle.

Other examples of personal cleaning elements are shampoos and soaps. Users try to clean external ear canals using these cleaning materials during bathing. Yet, ear cleaning using cleaning materials that are structurally not suitable for cleaning earwax may cause irritation of external ear canal, infection and insufficient production of cerumen.

For example, the conventional hair shampoos without pH 5.5 value or soap that makes the skin pH alkali, destroy the acidic protection layer of skin and may cause new infection to spread even more.

Such kind of unsuitable products may cause unbalance in ear canals instead of cleaning ear canals and avoiding infections.

Professional cleaning elements are not methods that can provide periodical ear cleaning at home for users. For application of such matters and methods, a specialized person must treat ears of the person. Examples of professional cleaning applications are aspirator or lavage (irrigation) applications. In aspirator method, earwax is cleaned using vacuum either with microscope or otoscope. Yet, this method is not preferred if the ear canal of corresponding person is so narrow, there is a hole in tympanic membrane or his/her immune system is weak.

In lavage application, ear canals are washed by a specialized person using water and softening solutions. In this method, the accumulated earwax in ear canal is softened using glycerin and similar softening mixtures, and following this, ear canals are washed using pressurized water. However, within the scope of said method, pressurized water reaches to middle ear and causes middle ear infection.

During the ear cleaning performed by means of abovementioned methods, there may develop irritation, bleeding on external ear canal, traumatic tears on tympanic membrane. Earwax softening drops alone hinders removal of the earwax from ears, because earwax swells due to glycerin and blocks external auditory canal further, and reduces process performance.

In patent application numbered EP 1337228, a mixture for helping in discharging the cerumen in human ear is disclosed. Said mixture comprises a carrier medium acceptable as bicarbonate and otologic, an enzyme acceptable as ceruminolytic, a carrier medium or bicarbonate acceptable as otologic, an enzyme acceptable as ceruminolytic and a carrier medium acceptable as otologic, in the structure thereof.

Mixture according to said patent is administered to ear canal via a dropper. In order to administer said mixture via ear canal, two different compounds forming the mixture according to the invention should be stored in two different areas on packs. Otherwise, the mixture cannot be used effectively. This increases the unit costs of said product.

The main reason that said mixture is kept in two different reservoirs is that the compounds in the structure are labile. The effectiveness of the product according to the invention decreases in the event that bicarbonate and other compounds used in the invention are mixed during storing before application.

On the other hand, it is difficult to apply the mixture to ears in drops and it is not possible to treat the whole of ear canals with the mixture. This decreases the efficiency of used mixture .

In the patent numbered US 4895875, there are stabilized peroxide solutions comprising . peroxide and glycerin, methods for preparing thereof and use for discharging cerumen disclosed.

The product disclosed in the patent numbered US 4895875 causes the cerumen in ears to swell due to glycerin and not to be discharged in many points from inside ear, and even accumulate in some parts by swelling.

On the other hand, said mixture can only be administered to ear canals in liquid form. A mixture in liquid form cannot diffuse the inner surface of ear canal completely, and therefore it cannot clean many parts of the ear interior canals . The Object Of the Invention:

The object of the invention is to present an ear cleaning product that provides ear cleaning without irritation and bleeding by its facilitating the removal of earwax effect in regular usage.

Another object of the invention is to provide a product formulation with active ingredient that can even be used in children.

Another object of the invention is to present an ear cleaning product in foam or shampoo form that can penetrate to the entire canal surface of the ear by its large surfaced form.

An object of the invention is that the surfactants included therein provide better cleaning of the earwax, which is a fat based secretion, and the accumulation of earwax is avoided with regular use.

Another object of the invention is to provide ease of use, ease of rinsing and effective dosing by its foam form.

An object of the invention is to present a mixture that allows discharging earwax without swelling it, and accordingly causing no blocking and irritation in external ear canals.

Another object of the invention is to form an ear cleaning product that has both ceruminolytic, cleaning and oil solving features .

An object of the invention is to form a product that facilitates personal use and increases effectiveness thanks to its foam form. Another object of the invention is to present an ear cleaning product without any infectious or infection increasing effect, and any decreasing or increasing effect on cerumen amount.

Another object of the invention is to form an ear and ear canal cleaning product compatible with skin, and which does not damage pH balance of skin.

Another object of the invention is to form an ear and ear canal cleaning product, which increases the efficiency of application in both personal and professional use, and provides an easier cleaning of earwax by applying to patients before lavage and aspirator methods.

Description of the Invention :

The invention is an ear, external ear canal, and ear wax cleaning mixture consisting of one or more active ingredients with ceruminolytic features; solvent substances; surfactants and auxiliary surfactants with cleaning and foaming feature; foam enhancing agents; viscosity enhancing agents; conditioners; moisturizers that exhibit humectant features and avoid drying; protective materials protecting the product from microbial contamination; pH regulators regulating pH of the product; hydrophilic emollients; emollients with re-oily and softening feature; aromatizing agents.

Preferred formulation of the product is in foam form. By this means the efficacy of a single unit is enhanced thanks to surface area, application simplicity, effective dosing and rinsing capabilities.

Yet, the product according to the invention can be brought into use as solutions (spray, drops, etc.), emulsion (cream, lotion, etc.), shampoo/soap (solid, liquid), foam, gel by using additional mixtures.

The present invention, in its structure, consists of composition of one or more substances of 0.1-10% docusate sodium, 0-10% triethanolamine polypeptide oleate condensate and 0-10% carbamide peroxide by weight as active ingredients. The main compound in the structure of the mixture that exhibits cleaning effect is this active ingredients or substances. In the structure of the mixture, the proportion of solvent substances by weight is 0.1-90%, proportion of surfactants with cleaning and foaming effect is 0.1-50% by weight, and the proportion auxiliary surfactants is 0-30% by weight that are used when necessary. Within the structure the foam enhancing agents with a proportion of 0-30% by weight; moisturizers that exhibit humectant features and avoid drying in skin with a proportion of 0-20%; solvent substances with an amount of 0.1-90%; protective substances that protects the product from microbial contaminant with a proportion of 0.01- 2%; pH regulator regulating pH of the product with a proportion of 0-10%, viscosity agents for adjusting viscosity of the product when necessary with a proportion of 0-10%, conditioners for providing softening effect on the product when necessary with a proportion of 0-10%, emollients for providing lubricating and softening effect on skin when necessary with a proportion of 0-20%, hydrophilic emollients for providing back fattening on skin when necessary with a proportion of 0-20%, aromatizer for aromatizing the product when necessary with a proportion of 0-5% are used.

When desired to be used in foam form, the product can contain solvents such as ethanol, water, hydrosol, etc.; surfactants such as decyl glucoside, sodium lauryl sulphate, sodium cocoamphoacetate, etc. that can be in anionic, nonionic, amphoteric structure; auxiliary surfactants such as disodium lauryl sulfosuccinate, cocamidopropyl betaine, etc. that can be in anionic, nonionic, amphoteric structure; foam enhancers such as sorbitan sesquicaprylate, capryl capramidopropyl betaine, etc.; protectors such as phenoxyethanol , potassium sorbate, sodium benzoate, methylisothiazolinone , methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; moisturizers such as glycerin, propylene glycol, etc.; pH regulators such as citric acid, sodium hydroxide, etc.; xanthan gum, etc. viscosity enhancers; aromatizers such as essence, essential oil, etc.; conditioners such as cetrimonium chloride, capryl capramidopropyl betaine, ethylhexylglycerin, cocamidopropyl betaine, etc. in its structure.

In addition to abovementioned compounds, it can also contain hydrophilic softener like polyglyceryl-4 caprate, etc. and emollients like caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc. in its foam form.

The product can be applied by spilling/rubbing and by foaming with water. Foam bottle/pump provides that the product can be present as foam. When desired that the product is in foam form, the mixture can be put into a foam bottle with a foaming mechanism.

For the product formulation described above with the general features thereof, there is a sample product mixture given below;

Docusate sodium

Carbamide peroxide

Triethanolamine polypeptide

Solvent/water phase

Surfactant Auxiliary Surfactant 0--30%

Foam enhancer 0- -30%

Moisturizer 0- -20%

Protector 0. .01-2%

pH regulator . 0- -10%

Viscosity enhancer 0- -10%

Conditioner 0- -10%

Emollient .0- -20%

Hydrophilic emollient 0- -20%

Aromatizer 0- -5%

When desired to be used as a solution, the formula contains solvents such as ethanol, water, etc.; xanthan gum, etc. viscosity enhancers; phenoxyethanol , potasium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc. protectors; glycerin, propylene glycol, etc. moisturizers; citric acid, sodium hydroxide, etc. pH regulators; caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc. emollients; stability enhancers like xanthan gum, carrageenan; aromatizers such as essence, essential oil, etc., in one or more different mixtures in its structure.

As the final product is liquid, the product can be used by spraying, dripping or spilling/rubbing.

For the product formulation described above with the general features thereof, there is a sample product mixture given below.

Docusate sodium 0.1-10%

Solvent 0.1-90%

Moisturizer 0-20%

Protector 0.01-2% pH regulator 0-10%

Viscosity enhancer 0-10%

Emollient 0-10%

Stability enhancer 0-5%

Aromatizer 0-5%

When desired to be used in emulsion form, the product contains solvent/water phase in the structure of which ethanol, water, hydrosol, etc; emulgators such as cetearyl glucoside, glyceryl stearate, etc.; auxiliary emulgators such as cetearyl alcohol, glyceryl stearate, etc.; stability enhancers such as xanthan gum, carrageenan, etc.; protectors such as phenoxyethanol , potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; moisturizers such as glycerin, propylene glycol, etc. ; viscosity enhancers such as xanthan gum, etc.; pH regulators such as citric acid, sodium hydroxide, etc.; antioxidants such as BHT, tocopherol, etc.; oil phase consisting of vegetable oil, synthetic oil, liquid paraffin, etc.; emollient consisting of caprylic/capric triglyceride, decyl cocoate, glyceryl laurate, etc.; antifoam agents such as dimethicone, etc., in one or more different mixtures in its structure.

As the product is in emulsion form, it can be used by spraying, dripping or spilling/rubbing.

Docusate sodium

Solvent/water phase

Emulgator

Auxiliary emulgator Oil phase 0-30%

Emollient 0-30%

Moisturizer 0-20%

Protector 0.01-2%

pH regulator 0-10%

Viscosity enhancer 0-10%

Stability enhancer 0-10%

Aromatizer 0-5%

Antioxidant 0-10%

Antifoam 0-10%

When desired to be used in shampoo/soap form, the product can contain solvents such as ethanol, water, hydrosol, etc.; surfactants such as decyl glucoside, sodium lauryl sulphate, sodium cocoamphoacetate., etc. that can be in anionic, nonionic, amphoteric structure; auxiliary surfactants such as disodium lauryl sulfosuccinate, cocamidopropyl betaine, etc. that can be in anionic, nonionic, amphoteric structure; foam enhancers such as sorbitan sesquicaprylate, capryl capramidopropyl betaine, etc.; viscosity enhancers such as xanthan gum, sodium chloride, etc.; protectors such as phenoxyethanol , potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; moisturizers such as glycerin, propylene glycol, etc.; pH regulators such as citric acid, sodium hydroxide, etc.; emollients such as caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc.; aromatizers such as essence, essential oil, etc.; conditioners such as cetrimonium chloride, capryl capramidopropyl betaine, ethylhexylglycerin, cocamidopropyl betaine, etc., in one or more different mixtures in its structure.

The product in shampoo or soap form can be applied by spilling/rubbing and by foaming with water. For solid soaps; saponifiers, caustic and materials for solidifying, can be added .

For the product formulation described above with the general features thereof, there is a sample product mixture given below .

Docusate sodium 0. .1-10%

Solvent/water phase 0, .1-90%

Surfactant 0. .01-50%

Auxiliary surfactant 0- -20%

Foam enhancer 0- -20%

Moisturizer 0- -20%

Protector 0. .01-2%

pH regulator 0- -10%

Viscosity enhancer 0- -10%

Conditioner 0- -10%

Emollient 0- -10%

Aromatizer 0- -5%

When desired to be used in gel form, the product can contain solvents such as ethanol, water, etc.; gelling agents such as carrageenan, xanthan gum, rhizobium gum, carbomer, etc. ; viscosity ^' enhancers such as xanthan gum, etc. when necessary; protectors such as phenoxyethanol , potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; moisturizers such as glycerin, propylene glycol, etc.; pH regulators such as citric acid, sodium hydroxide, TEA, etc.; emollients such as caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc.; aromatizers such as essence, essential oil, etc., in one or more different mixtures in its structure. P T/TR2014/000178

The product can be applied by spraying, dripping or spilling/rubbing.

Docusate sodium 0.1-10%

Solvent 0.1-90%

Gelling agent 0.01-30%

Moisturizer 0-20%

Protector 0.01-2%

pH regulator 0-10%

Viscosity enhancer 0-10%

Emollient 0-10%

Aromatizer 0-5%

Claims

An ear cleaning mixture for ear, external ear canal and ear wax cleaning that can be directly applied to the external ear canals, characterized in that; it is a mixture in foam form consisting of an active ingredient consisting of one or more substances of docusate sodium, triethanolamine . polypeptide oleate condensate and carbamide peroxide with ceruminolytic feature; solvents; surfactants and auxiliary surfactants with cleaning and foaming feature; foam enhancing agents; viscosity enhancing agents; conditioners; hydrophilic emollients; moisturizers that exhibit humectant features and avoid drying on skin; protective materials protecting the product from microbial contamination; pH regulator regulating. pH of the product; and re-oily; aromatizing agents and emollients with softening features.

An ear cleaning mixture in foam form according to Claim 1, characterized in that; the mixture is positioned into a foam bottle with a foaming mechanism.

A mixture according to Claim 1, characterized in that; it consists of an active ingredient consisting of one or more mixture of 0.1-10% docusate sodium, 0-10% triethanolamine polypeptide oleate condensate and 0-10% carbamide peroxide; 0.1-90% solvent substances, 0.1-50% surfactants, 0-30% auxiliary surfactants, 0-30% foam enhancing agents, 0-20% moisturizing agents, 0.01-2% protective materials, 0-10% pH regulating materials, 0- 10% viscosity enhancing agents, 0-10% conditioner, 0-20% hydrophilic emollients, 0-20% emollient and 0-5% aromatizing agents, by weight.

Solvent according to Claim 3, characterized in that; can be ethanol, water, hydrosol .

5. Surfactant according to Claim 3, characterized in that; it can be decyl glucoside, sodium lauryl sulphate and sodium cocoamphoacetate in anionic, nonionic, amphoteric structure.

Auxiliary surfactants according to Claim 3, characterized in that; it can be disodium lauryl sulfosuccinate and cocamidopropyl betaine in anionic, nonionic, amphoteric structure.

7. Foam enhancer agents according to Claim 3, characterized in that; it can be sorbitan sesquicaprylate and capryl capramidopropyl betaine.

8. Protective materials according Claim 3, characterized in that; it can be phenoxyethanol , potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone and dimethyl dimethyl hydantoin .

9. Moisturizing agents according to Claim 3, characterized in that; it can be glycerin and propylene glycol.

10. pH regulator according to Claim 3, characterized in that; it can be citric acid and sodium hydroxide.

11. Aromatizing agents according to Claim 3, characterized in that; it can be in essence, essential oil structure.

12. Conditioner according to Claim 3, characterized in that; it can be cetrimonium chloride, capryl capramidopropyl betaine, ethylhexylglycerin, cocamidopropyl betaine, etc.

13. Hydrophilic emollient according to Claim 3, characterized in that; it can be polyglyceryl-4 caprate.

14. Viscosity enhancing agents according to Claim 3, characterized in that; it can be xanthan gum.

15. Emollient according :to Claim 3, characterized in that; it can be caprylic/capric triglyceride, decyl cocoate and glyceryl laurate.

16. Mixture according to Claim 1, characterized in that;

it can be used in solution, emulsion, shampoo, soap, gel forms .

17. An ear cleaning mixture in solution form according to foregoing Claims, characterized in that; it consists of 0.1-10% docusate sodium; 0.1-90% solvents such as ethanol, water, etc.; 0-10% viscosity enhancers such as xanthan gum, etc.; 0.01-2% protectors such as phenoxyethanol , potassium sorbate, sodium benzoate, potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone and dimethyl dimethyl hydantoin, etc.; 0-20% moisturizers such as glycerin and propylene glycol, etc.; 0-10% pH regulators such as citric acid and sodium hydroxide, etc.; 0-5% essence and essential oils; 0-10% emollients such as caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc.; 0-5% stability enhancers such as xanthan gum, carrageenan, etc., by weight.

18. An ear cleaning mixture in emulsion form according to foregoing Claims, characterized in that; it consist of 0.1-10% docusate sodium; 0.1-90% solvents such as ethanol, water, and hydrosol, etc.; 0.1-20% auxiliary emulgators such as sterile alcohol and glyceryl stearate, etc.; 0.1-30% emulgators such as cetearyl glucoside, glyceryl stearate citrate; 0-10% stability enhancers such as xanthan gum and carrageenan, etc.; 0.01-2% protectors such as phenoxyethanol, potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; 0-20% moisturizers such as glycerin, propylene glycol, etc.; 0-10% viscosity enhancers such as xanthan gum, etc.; 0-10% pH regulators such as citric acid and sodium hydroxide, etc.; 0-5% aromatizers such as essence, essential oil, etc.; 0-10% antioxidants such as BHT and tocopherol, etc.; 0-30% oil phase consisting of vegetable oil, synthetic oil, liquid paraffin, etc.; 0-30% emollient consisting of caprylic/capric triglyceride, decyl cocoate, glyceryl laurate, etc.; and 0-10% antifoams such as dimethicone, etc. by weight in one or more different mixtures in its structure.

19. An ear cleaning mixture in shampoo/soap form according to foregoing Claims, characterized in that; it consist of 0.1-10% docusate sodium; 0.1-90% solvents such as ethanol, water, and hydrosol, etc.; 0.1-50% surfactants such as decyl glucoside, sodium lauryl sulphate, sodium cocoamphoacetate, etc. that can be in anionic, nonionic, amphoteric structure; 0-20% auxiliary surfactants such as disodium lauryl sulfosuccinate, cocamidopropyl betaine, etc. that can be in anionic, nonionic, amphoteric structure; 0-20% foam enhancers such as sorbitan sesquicaprylate , capryl capramidopropyl betaine, etc.; 0-10% viscosity enhancers such as xanthan gum and sodium chloride, etc.; 0.01-2% protectors such as phenoxyethanol, potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone, dimethyl dimethyl hydantoin, etc.; 0-20% moisturizers such as glycerin and propylene glycol, etc.; 0-10% pH regulators such as citric acid and sodium hydroxide, etc.; 0-5% aromatizers such as essence and essential oil, etc.; 0-10% conditioners such as cetrimonium chloride, capryl capramidopropyl betaine, ethylhexylglycerin, cocamidopropyl betaine, etc.; 0-10% emollients such as caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc. by weight, in one or more different mixtures in its structure.

20. An ear cleaning mixture in gel form according to foregoing Claims, characterized in that; it consist of 0.1-10% docusate sodium; 0.1-90% solvents such as ethanol, water, etc.; 0.01-30% gelling agents such as carrageenan, xanthan gum, rhizobium gum, and carbomer, etc.; 0-10% viscosity enhancers such as xanthan gum, etc.; 0-20% moisturizers such as glycerin and propylene glycol, etc.; 0-10% pH regulators such as citric acid, sodium hydroxide, and TEA, etc.; 0.01-2% protectors such as phenoxyethanol, potassium sorbate, sodium benzoate, methylisothiazolinone, methylchloroisothiazolinone , dimethyl dimethyl hydantoin, etc.; 0-10% emollients such as caprylic/capric triglyceride, decyl cocoate and glyceryl laurate, etc.; and 0-5% aromatizers such as in essence and essential oil form, etc. by weight, in one or more different mixtures in its structure.