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WO2014167436A3 - Sunitinib glucuronate salt & process for preparation thereof - Google Patents

Sunitinib glucuronate salt & process for preparation thereof Download PDF

Info

Publication number
WO2014167436A3
WO2014167436A3 PCT/IB2014/060023 IB2014060023W WO2014167436A3 WO 2014167436 A3 WO2014167436 A3 WO 2014167436A3 IB 2014060023 W IB2014060023 W IB 2014060023W WO 2014167436 A3 WO2014167436 A3 WO 2014167436A3
Authority
WO
WIPO (PCT)
Prior art keywords
sunitinib
acid addition
addition salt
preparation
glucuronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2014/060023
Other languages
French (fr)
Other versions
WO2014167436A2 (en
Inventor
Rampalli SRIRAM
Upalla LAVKUMAR
Seshagiri VIJAYA MURALI MOHANRAO
Pradeep SHIVAKUMAR
Akshaykant CHATURVEDI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shilpa Medicare Ltd
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Publication of WO2014167436A2 publication Critical patent/WO2014167436A2/en
Publication of WO2014167436A3 publication Critical patent/WO2014167436A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to novel pharmaceutically acceptable glucuronic acid addition salt of Sunitinib Formula (I) or its solvate thereof. The present invention further relates to the processes for preparation of the glucuronic acid addition salt of Sunitinib. Glucuronic acid addition salt of Sunitinib (I) prepared according to the process of the present invention is obtained as a solid material. The pharmaceutical compositions comprising glucuronic acid addition salt of Sunitinib or its solvate thereof may be useful as anti-cancer agent.
PCT/IB2014/060023 2013-04-10 2014-03-21 Sunitinib glucuronate salt & process for preparation thereof Ceased WO2014167436A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1629/CHE/2013 2013-04-10
IN1629CH2013 2013-04-10
IN5614CH2013 2013-12-06
IN5614/CHE/2013 2013-12-06

Publications (2)

Publication Number Publication Date
WO2014167436A2 WO2014167436A2 (en) 2014-10-16
WO2014167436A3 true WO2014167436A3 (en) 2015-02-19

Family

ID=51690077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/060023 Ceased WO2014167436A2 (en) 2013-04-10 2014-03-21 Sunitinib glucuronate salt & process for preparation thereof

Country Status (1)

Country Link
WO (1) WO2014167436A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010041134A1 (en) * 2008-10-10 2010-04-15 Medichem, S.A. Process for preparing a 3-pyrrole subsituted 2-indolinone malate salt
WO2011033472A1 (en) * 2009-09-16 2011-03-24 Ranbaxy Laboratories Limited Salts of sunitinib
US20110118477A1 (en) * 2008-07-24 2011-05-19 Teva Pharmaceutical Industries Ltd. Sunitinib and salts thereof and their polymorphs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110118477A1 (en) * 2008-07-24 2011-05-19 Teva Pharmaceutical Industries Ltd. Sunitinib and salts thereof and their polymorphs
WO2010041134A1 (en) * 2008-10-10 2010-04-15 Medichem, S.A. Process for preparing a 3-pyrrole subsituted 2-indolinone malate salt
WO2011033472A1 (en) * 2009-09-16 2011-03-24 Ranbaxy Laboratories Limited Salts of sunitinib

Also Published As

Publication number Publication date
WO2014167436A2 (en) 2014-10-16

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