Classifications

• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
  • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
  • B01L3/5021—Test tubes specially adapted for centrifugation purposes
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
  • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
  • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D2221/00—Applications of separation devices
  • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
  • B01L2200/02—Adapting objects or devices to another
  • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2300/00—Additional constructional details
  • B01L2300/04—Closures and closing means
  • B01L2300/041—Connecting closures to device or container
  • B01L2300/042—Caps; Plugs
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2300/00—Additional constructional details
  • B01L2300/04—Closures and closing means
  • B01L2300/046—Function or devices integrated in the closure
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2300/00—Additional constructional details
  • B01L2300/08—Geometry, shape and general structure
  • B01L2300/0848—Specific forms of parts of containers
  • B01L2300/0858—Side walls
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2400/00—Moving or stopping fluids
  • B01L2400/04—Moving fluids with specific forces or mechanical means
  • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
  • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2400/00—Moving or stopping fluids
  • B01L2400/04—Moving fluids with specific forces or mechanical means
  • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
  • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Definitions

• the invention relates to a centrifuge tube structure, in particular to a centrifuge tube structure for conveniently extracting a thin layer solution.
• the upper liquid is mainly plasma
• the lower liquid is mainly red blood cells
• the middle liquid is a blood clot yellow layer, mainly platelets, white blood cells and stem cells.
• the yellow blood clot is especially valuable because of its medical and commercial value.
• the yellow layer of the blood clot in the test tube is a thin layer. Because the thickness of the yellow layer of the blood clot is small, it is not easy to extract in an ordinary test tube, so it is necessary to be extra careful when extracting, otherwise it is easy to accidentally extract the upper liquid. Or the lower layer of liquid, so this step is indeed difficult for the extractor to operate.
• the biological device comprises a body 11 and a top cover 10.
• the body 11 has a bottle neck portion 110, and the top cover 10 is movable forwardly and backwardly in the longitudinal direction of the body 11, and the top cover 10 is operated by a user to rotate the top cover 10 along the body. 11 forward and backward.
• the top cover 10 of the biological device has no need for movement.
• top cover 10 can be changed to a fixed type, even if the top cover 10 and the body 11 are integrally formed, the structure and the ease of manufacture thereof will be In addition, if the top cover 10 is modified from the movable type to the fixed body 11, the biological device can be emphasized as a one-time use, so as to prevent the unscrupulous person from lowering the cost of the biological device.
• the cover 10 is unscrewed, removed, cleaned and reused.
• the biological device further includes a bottom cover 13, and the bottom cover 13 is operated by rotation by an operator to advance and retreat the bottom cover 13 in the longitudinal direction of the body 11.
• the package further discloses an encapsulation portion 12 for closing the lower storage tank 120 of the body 11.
• the operator can rotate the bottom cover 13 to push the encapsulation portion 12, thereby reducing The volume of the storage tank 120 is reduced.
• the operator's action of twisting the bottom cover by the finger causes the force component of the force application to be perpendicular to the longitudinal axis of the body 11 when the force is applied, so that the entire biological device is likely to be shaken left and right, resulting in It is clear that the layered upper liquid, the middle liquid, and the lower liquid are mutually mixed.
• a centrifugal tube structure which not only facilitates the extraction of the stratified solution, but also greatly simplifies the structure for manufacturing convenience, and further ensures the disposable use of the centrifuge tube structure, and reduces the use of the lower storage tank.
• the operator's direction of application is along a longitudinal axis to avoid sloshing the layered solution in the centrifuge tube structure, which is a current goal in the industry.
• the main object of the present invention is to provide a centrifugal tube structure, which fixes the first blocking body to the first receiving groove to ensure that it is used once and at the same time simplifies the structure. Designed for easier manufacturing.
• Another object of the present invention is to provide a centrifugal tube structure that receives an axial thrust, so that when the solution pushed into the centrifuge tube structure rises, it is difficult to shake left and right, so that the operator extracts the layered solution. .
• the technical solution provided by the present invention is to provide a centrifuge tube structure, comprising a tube body, a first blocking body and a second blocking body, the tube body having a first receiving groove, a second accommodating groove and a necking portion connecting the first accommodating groove and the second accommodating groove; the first blocking body is fixed to the first accommodating groove, and the first accommodating groove
• the second blocking body includes a bottom cover and a piston portion, the bottom cover is fixed to the bottom end of the second receiving groove, and the piston portion closes the second receiving groove;
• the piston portion is received in the second accommodating groove, and the piston portion and the second accommodating groove together define a variable volume space; wherein the neck portion defines a communication channel, and the communication channel The fixed volume space and the variable volume space are communicated.
• the first receiving groove has a first opening
• the first blocking body is fixed to the first opening of the first receiving groove.
• the first blocking body and the first receiving groove are integrally formed.
• the first blocking body has an air hole corresponding to the necking portion, wherein the fixed volume space is connected to an outside via the air hole.
• the first blocking body further has a liquid inflow hole, and the liquid inflow hole is adjacent to the air hole.
• the first blocking body includes two plugs for blocking the liquid inflow hole and the air hole respectively; wherein the plug blocking the air hole has a socket, and a fine pin is disposed through The plug of the plug a hole to enter the first receiving groove.
• the neck portion has a cross-sectional area smaller than a cross-sectional area of the first receiving groove and a cross-sectional area of the second receiving groove.
• the piston portion moves in the second accommodating groove to define the variable volume space together with the second accommodating groove; or the piston portion is received in the second accommodating groove, And the piston portion is adapted to receive an external force to deform to jointly define the variable volume space with the second receiving groove.
• the second blocking body further includes a push rod, and a central portion of the bottom cover is a hollow portion; the push rod passes through the hollow portion and is connected to the piston portion, and the push rod receives an external force The push rod is adapted to push the piston portion toward the neck portion.
• the present invention also provides a centrifuge tube structure, comprising a tube body, a first blocking body and a second blocking body, the tube body having a first receiving groove, a second receiving groove and connecting the same a first receiving groove and a necking portion of the second receiving groove; the first blocking body is fixed to the first receiving groove and defines a fixed volume space together with the first receiving groove; The second blocking body and the second receiving groove define a variable volume space; wherein the necking portion defines a communication passage, and the communication passage communicates with the fixed volume space and the variable volume space.
• the first blocking body and the first receiving groove are integrally formed.
• the first receiving groove has a first opening, and the first blocking body is fixed to the first opening.
• the first blocking body has an air hole corresponding to the necking portion, wherein the fixed volume space is connected to an outside via the air hole.
• the first blocking body further has a liquid inflow hole, and the liquid inflow hole is adjacent to the air hole.
• the first blocking body includes two plugs for blocking the liquid inflow hole and the air hole respectively; wherein the plug blocking the air hole has a socket, and a fine pin is disposed through The jack of the plug is inserted into the first receiving slot.
• the neck portion has a cross-sectional area smaller than a cross-sectional area of the first receiving groove and a cross-sectional area of the second receiving groove.
• the second blocking body includes a piston portion, and the piston portion is received in the second receiving groove and moves in the second receiving groove to define the second receiving groove.
• the second blocking body includes a piston portion, the piston portion is received in the second receiving groove, and the piston portion is adapted to receive an external force to deform
• the second receiving groove collectively defines the variable volume space.
• the second blocking body further includes a bottom cover, and the bottom cover is disposed at a bottom end of the second receiving groove, such that the piston portion is located between the bottom cover and the neck portion.
• the bottom cover is movably disposed in the second receiving groove, and when the bottom cover moves toward the neck portion, the bottom cover is adapted to push the piston portion together, and the piston portion faces the The neck is moving.
• the surface of the bottom cover is formed with a male thread
• the surface of the second receiving groove is formed with a female thread
• the male thread is adapted to cooperate with the female thread to make the bottom cover rotate in an axial direction. It is appropriate to make a movement along the axial direction at the same time.
• the bottom cover has a negative structure
• the second receiving groove has a positive structure
• the negative structure is adapted to cooperate with the male structure to make the bottom cover slide relative to the second receiving groove.
• the bottom cover is fixed to the second receiving groove, and a central portion of the bottom cover is a hollow portion.
• the second blocking body further comprises a push rod, wherein the push rod passes through the hollow portion and is connected to the piston portion, and when the push rod receives an external force, the push rod is adapted to push the piston portion Move toward the neck portion.
• the second blocking body further includes a push rod, wherein the push rod is coupled to the piston portion, and when the push rod receives an external force, the push rod is adapted to push the piston portion toward the neck portion .
• the present invention also provides a centrifuge tube structure, comprising a tube body, a fixed cover body and a bottom cover, the tube body having a first accommodating groove, a second accommodating groove and connecting the first accommodating groove a fixing portion of the second accommodating groove; wherein the first accommodating groove has a fixing means; the fixing cover body is coupled to the fixing means of the first accommodating groove, and the fixing means makes the fixing The cover body is fixed to the first receiving groove; the bottom cover is disposed at the bottom end of the second receiving groove.
• the fixed cover body has air holes and a liquid inlet and outlet hole corresponding to the neck portion; wherein the fixed volume space is connected to an outside through the air hole.
• a pumping device When a pumping device is housed in the liquid inlet and outlet, a portion of the pumping device enters the neck portion.
• the centrifugal tube structure further includes a piston portion, and the piston portion is received in the second receiving groove and movable in the second receiving groove.
• the second receiving slot has a movable means
• the bottom cover is coupled to the movable means to enable the bottom cover to be movably disposed in the second receiving groove.
• the piston portion is located between the bottom cover and the neck portion.
• the bottom cover moves toward the neck portion, the bottom cover is adapted to push the piston portion together, and the piston portion faces the neck portion. The contraction moves.
• the movable means of the second accommodating groove is a female thread of the second accommodating groove, and a surface of the bottom cover is formed with a male thread, and the male thread is adapted to cooperate with the female thread to make the bottom
• the cover is rotated in an axial direction It is appropriate to move at the same time along the axial direction.
• the movable means of the second receiving groove is a positive structure of the second receiving groove
• the bottom cover has a negative structure
• the male structure is adapted to cooperate with the negative structure, so that the bottom cover can be opposite
• the second receiving groove is made to slide.
• the centrifuge tube structure further includes a push rod, wherein the push rod is coupled to the piston portion, and the push rod is adapted to push the piston portion toward the neck portion when the push rod receives an external force.
• the present invention also provides a centrifuge tube structure, comprising a tube body, a first blocking body and a second blocking body, the tube body having a first receiving groove, a second receiving groove and connecting the same a first receiving groove and a necking portion of the second receiving groove; the first blocking body is fixed and limited to the upper edge of the groove of the first receiving groove; the second blocking body is movably coupled to The lower edge of the groove of the second accommodating groove; wherein, the first blocking body, the first accommodating groove, the necking portion, the second accommodating groove and the second blocking body are common A volume space is defined; a capacity distribution state of the volume space can be changed by moving the second blocking body.
• the second blocking body further includes a piston portion, and the piston portion is received in the second receiving groove and movable in the second receiving groove.
• the second blocking body further includes a push rod connected to the piston portion; wherein the push rod is adapted to push along a longitudinal axis when the push rod receives an axial thrust
• the piston portion linearly moves toward the neck portion to reduce the volume; or, when the push rod receives an axial pulling force, the push rod is adapted to pull the piston portion along a longitudinal axis, Moving linearly away from the necking to increase the volume.
• one end of the push rod is connected to the piston portion to be integrally formed with the piston portion; or, one end of the push rod is hooked to the piston portion.
• the second blocking body further includes a bottom cover, the bottom cover is movably disposed at a lower edge of the groove of the second receiving groove; wherein, when the bottom cover moves toward the necking portion, The bottom cover is adapted to push the piston portion together to move the piston portion toward the neck portion to reduce the volume; or, when the bottom cover moves away from the neck portion, the bottom cover Preferably, the piston portion is pulled together to move the piston portion away from the neck portion to increase the volume.
• the present invention also provides a centrifuge tube structure, comprising a tube body, a first blocking body and a second blocking body, the tube body having a first receiving groove, a second receiving groove and connecting the same a first receiving groove and a necking portion of the second receiving groove; the first blocking body covers the first receiving groove; the second blocking body comprises a bottom cover and a piston portion, the bottom The cover is fixed to the bottom end of the second accommodating groove, the piston portion closes the second accommodating groove, and the piston portion is movable in the second accommodating groove.
• the centrifugal tube structure further includes a push rod, wherein the push rod is connected to the piston portion, and when the push rod receives an axial thrust, the push rod is adapted to push the piston portion along a longitudinal axis The direction moves linearly in the direction of the neck portion.
• the central portion of the bottom cover is a hollow portion.
• the centrifugal tube structure further comprises a push rod, wherein the push rod passes through the hollow portion and is connected to the piston portion, and when the push rod receives an axial top thrust, the push rod is adapted to push the piston The portion moves linearly in the direction of the neck portion along a longitudinal axis.
• the first blocking body is fixed to the first receiving groove to define a fixed volume space together with the first receiving groove; or the first blocking body is movably disposed on the first blocking body A receiving groove cooperates with the first receiving groove to define a variable volume space.
• the first blocking body has an air hole corresponding to the necking portion, wherein the fixed volume space or the variable volume space is connected to an outside via the air hole.
• the first blocking body further has a liquid inflow hole, and the liquid inflow hole is adjacent to the air hole.
• the first blocking body includes two plugs for blocking the liquid inflow hole and the air hole respectively; wherein the plug blocking the air hole has a socket, and a fine pin is disposed through The jack of the plug is inserted into the first receiving slot.
• the necked portion has a cross-sectional area smaller than a cross-sectional area of the first receiving groove and a cross-sectional area of the second receiving groove, respectively.
• the present invention also provides a centrifuge tube structure comprising a tube body, a first blocking body, a piston portion and a push rod, the tube body having a first receiving groove, a second receiving groove and a connection a first necking groove and a necking portion of the second receiving groove; the first blocking body covers the first receiving groove; the piston portion closes the second receiving groove, and the piston portion can Moving in the second accommodating groove; the push rod is connected to the piston portion, and when the push rod is pushed by an external force, the piston portion is correspondingly pushed along a longitudinal axis toward the neck portion The direction moves in a straight line.
• the external force received by the push rod is an axial top thrust to urge the piston portion to move linearly in a longitudinal direction toward the neck portion.
• the centrifuge tube structure further includes a bottom cover fixed to the bottom end of the second receiving groove, such that the piston portion is located between the bottom cover and the neck portion.
• the first blocking body is fixed to the first receiving groove to define a fixed volume space together with the first receiving groove; or the first blocking body is movably disposed on the first blocking body A receiving groove cooperates with the first receiving groove to define another variable volume space.
• the first blocking body has an air hole corresponding to the necking portion; the fixed volume space or the variable volume space is connected to an outside via the air hole.
• the present invention also provides a centrifuge tube structure, comprising a tube body, a first blocking body and a movable member, the tube body having a first receiving groove, a second receiving groove and connecting the first volume a necking portion and a necking portion of the second receiving groove; the first blocking body covers the first receiving groove; the movable member closes the second receiving groove, and the movable member is adapted to receive an axis The thrust is pushed upward to linearly move the movable member in a longitudinal direction toward the neck portion.
• the movable member includes a piston portion that together with the second receiving groove defines a variable volume space.
• the movable member further includes a push rod connected to the piston portion; wherein the push rod is adapted to receive the axial top thrust to push the piston portion along the axial direction toward the neck portion Moving, the variable volume is reduced.
• the first blocking body is fixed to the first receiving groove to define a fixed volume space together with the first receiving groove; or the first blocking body is movably disposed on the first blocking body A receiving groove cooperates with the first receiving groove to define another variable volume space.
• the first blocking body has an air hole corresponding to the necking portion; wherein the fixed volume space or the variable volume space is connected to an outside via the air hole.
• the present invention also provides a centrifuge tube structure, comprising a tube body, a first blocking body and a movable member, the tube body having a first receiving groove, a second receiving groove and communicating the first volume a necking portion of the groove and the second receiving groove; the first blocking body covers the upper edge of the groove of the first receiving groove; the movable member closes the lower edge of the groove of the second receiving groove Wherein, a total volume space is defined between the first blocking body, the first receiving groove, the necking portion, the second receiving groove and the movable member, and the movable member is suitable An axial thrust is applied to move the movable member linearly in a longitudinal direction toward the neck portion and change a capacity distribution state of the total volume space.
• the movable member includes a piston portion that is received in the second receiving groove and movable in the second receiving groove.
• the movable member further includes a push rod connected to the piston portion; wherein the push rod is adapted to push the piston portion along a longitudinal axis when the push rod receives an axial thrust Moving linearly in the direction of the neck portion to reduce the total volume space; or, when the push rod receives an axial pulling force, the push rod is adapted to pull the piston portion along a longitudinal axis, Moving linearly away from the necking to increase the total volume.
• one end of the push rod is connected to the piston portion to be integrally formed with the piston portion; or, one end of the push rod is hooked to the piston portion.
• the movable member further includes a bottom cover movably disposed at a lower edge of the groove of the second receiving groove; wherein the bottom cover is moved when the bottom cover moves toward the neck portion
• the piston portion is pushed to move the piston portion toward the neck portion to reduce the total volume space; or, when the bottom cover moves away from the neck portion, the bottom cover is adapted
• the piston portion is pulled together to move the piston portion away from the neck portion to increase the total volume.
• the centrifuge tube structure of the present invention makes it easier for the operator to extract the layered solution by designing a neck portion having a narrower cross-sectional area.
• the centrifuge tube structure of the present invention can be designed such that the first blocking body and the first receiving groove are fixed to each other and cannot be relatively moved or separated to ensure that the centrifugal tube structure disclosed in the present invention is disposable and simplified at the same time.
• the structural design of the centrifuge tube structure makes it easier to mass-produce in manufacturing.
• the centrifugal tube structure of the present invention can also be designed such that the bottom cover is fixed at the lower edge of the groove body of the second accommodating groove, so that the piston portion is limited.
• the movable member of the present invention is designed to receive an axial force to push the piston portion, so that when the operator performs the pulling action, the force can be prevented from being applied in other directions, which may result in a component force. It is applied to the structure of the centrifuge tube to cause the structure of the centrifuge tube to shake side to side.
• FIG. 1 is a schematic cross-sectional view of a conventional biological device.
• Figure 2 is a schematic cross-sectional view showing the first embodiment of the centrifuge tube structure of the present invention before the blood has been pushed up.
• Fig. 3 is a cross-sectional view showing the first embodiment of the structure of the centrifuge tube of the present invention after the blood has been pushed up and inserted into the fine needle.
• Figure 4 is a cross-sectional view showing a second embodiment of the centrifuge tube structure of the present invention.
• Figure 5 is a cross-sectional view showing a third embodiment of the centrifugal tube structure of the present invention.
• Figure 6 is a cross-sectional view showing a fourth embodiment of the centrifugal tube structure of the present invention.
• Figure 7 is a cross-sectional view showing a fifth embodiment of the centrifugal tube structure of the present invention.
• Figure 8 is a cross-sectional view showing a sixth embodiment of the centrifugal tube structure of the present invention.
• Figure 9 is a cross-sectional view showing a seventh embodiment of the centrifugal tube structure of the present invention.
• Figure 10 is a cross-sectional view showing the eighth embodiment of the centrifugal tube structure of the present invention.
• Figure 11 is a cross-sectional view showing a ninth embodiment of the structure of the centrifuge tube of the present invention. detailed description
• the main inventive spirit of the present invention is to disclose a centrifuge tube structure for accommodating blood to be separated and doped with a small amount of anticoagulant to prevent blood from solidifying during operation.
• the centrifuge tube structure containing the blood is placed in a general centrifuge to perform a centrifugal operation.
• the principle is that, due to the different specific gravity of various components contained in the blood, the centrifugal action is performed using a centrifuge tube structure and a centrifuge, and after standing for a period of time, the blood in the centrifuge tube structure is clearly layered into three layers.
• the solution, the upper layer solution is a plasma layer
• the middle layer solution is a blood clot layer
• the lower layer solution is a red blood cell layer.
• the yellow layer of blood clot sandwiched between the plasma layer and the red blood cell layer is rich in a large amount of growth factors, which helps to repair the function of the aging tissue, promotes metabolism and regenerates the skin, and is often applied to the medical treatment process. And make it rich in commercial value.
• the centrifugal tube structure of the present invention is designed to facilitate the extraction of a thin layer solution (in the present invention, it is convenient to extract the yellow blood layer of the blood clot). Centrifuge tube structure.
• FIG. 2 and FIG. 3 are schematic cross-sectional views showing the blood in the centrifuge tube structure of the first embodiment of the present invention before and after being lifted.
• the centrifuge tube structure of the present invention comprises a tube body 2 having a first accommodating groove 20, a second accommodating groove 22 and a necking portion 21, and the necking portion 21 is connected to the first accommodating groove 20. And the second accommodating groove 22.
• the cross-sectional area of the neck portion 21 is smaller than the cross-sectional area of the first accommodating groove 20 and the cross-sectional area of the second accommodating groove 22, that is, the neck portion 21 of the centrifuge tube structure is tapered, and the centrifuge tube structure is made.
• the overall shape presents an hourglass shape.
• the structure of the centrifuge tube further includes a first blocking body 3 and a second blocking body 4.
• the first blocking body 3 is fixed and limited to the groove of the first receiving groove 20.
• the upper edge is incapable of moving
• the second blocking body 4 is movably coupled to the lower edge of the groove of the second receiving groove 22.
• the first resisting body 3, the first accommodating groove 20, the necking portion 21, the second accommodating groove 22 and the second blocking body 4 jointly define a total volume space 5, and By moving the second blocking body 4, a capacity distribution state of the total volume space 5 can be changed.
• the first blocking body 3 is fixed to the first receiving groove 20, the first blocking body 3 and the first receiving groove 20 together define a fixed volume space 200; similarly, The second blocking body 4 is movably disposed in the second accommodating groove 22, so that the second blocking body 4 and the second accommodating groove 22 together define a variable volume space 220; and by the necking portion 21 a defined communication channel 210, connecting the fixed volume space 200 with the variable The volume space 220, in other words, the total volume space 5 is formed by the fixed volume space 200, the communication passage 210, and the variable volume space 220.
• the first resisting body 3 and the first receiving groove 20 may be fixed in the first blocking body 3.
• the first accommodating groove 20 is integrally formed with the first accommodating groove 20 (as shown in FIG. 2 and FIG. 3); or, as shown in FIG. 4, the first accommodating groove 20 can have a fixing means 205, and
• the fixing body 3 is a fixing cover 35.
• the fixing cover 35 is fastened to the fixing means 205 of the first receiving groove 20, and the fixing cover 35 is fixed to the first receiving groove 20 by the fixing means 205.
• the first resisting member 3 can be fixed to a first opening portion 201 of the first accommodating groove 20 by any fixing manner such as snapping, inlaying, and fixing.
• the centrifugal tube structure is used in an upright position, wherein the first resisting body 3 is located above and the second blocking body 4 is located below. Since the blood is contained in the total volume 5, if the blood has completed the separation step, a three-layered layered solution is present in the total volume space 5. At this time, if the second blocking body 4 is pushed to move toward the necking portion 21, the total volume space 5 can be reduced, and the solution of each layer can be moved up; otherwise, if the second blocking body 4 is pulled away from the necking When the portion 21 moves, the total volume space 5 can be increased, and the solution of each layer is lowered.
• the height of each layer solution can be adjusted by operating the second blocking body 4, so that any layer solution in each layer solution is adjusted to be located at the necking portion 21. It is affected by the reduction in the cross-sectional area of the neck portion 21, which increases the thickness of the layer solution, and allows the operator to perform a large increase in the ease of extracting the layer solution.
• the first resist 3 has an air hole 202 and a liquid inflow hole 203.
• the first resist 3 includes There are two plugs 204, 204', and when the centrifugal action is performed, the liquid inflow holes 203 and the air holes 202 on the first blocking body 3 can be blocked by the two plugs 204, 204', respectively.
• the plug 204' has a through hole 204'a for inserting a thin needle 6.
• the position of the air hole 202 corresponds to the neck portion 21, and when the thin needle 6 is received in the through hole 204'a, a part of the fine needle 6 can enter the first receiving groove 20 to take the points in the total volume space 5.
• Layer solution the user can take any solution in the stratified solution according to the actual demand situation, and is not limited herein.
• the air hole 202 is adjacent to the liquid inflow hole 203 for a liquid to be injected from the outside, and the total volume space 5 is gas-connected to the outside through the air hole 202.
• the purpose of setting the stomata 202 is, when the blood When the total volume space 5 is injected, a part of the space in the total volume space 5 is occupied by the blood, so that the gas originally contained in the total volume space 5 can be discharged to the outside through the air holes 202.
• the second blocking body 4 includes a piston portion 41.
• the piston portion 41 is received in the second accommodating groove 22 and movable in the second accommodating groove 22.
• the user can change the capacity distribution state of the total volume space 5 by moving the piston portion 41.
• the user can push the piston portion 41 to reduce the total volume space 5 or pull the piston portion 41 to increase the total volume space 5.
• the total volume space 5 can also be reduced or increased, which is also a possible embodiment of the piston portion 41 of the centrifugal tube structure of the present invention.
• FIG. 5 to FIG. 6 are schematic cross-sectional views showing the third and fourth embodiments of the centrifuge tube structure of the present invention.
• FIG. 5 is an example in which the first blocking body 3 and the first receiving groove 20 are integrally formed.
• FIG. 6 is an example in which the first blocking body 3 is capped on the first accommodating groove 20 .
• this is only an enumeration of the relationship between the first blocking body 3 and the first accommodating groove 20 , and thus is not limited thereto.
• Another possible way of fixing the resist 3 and the first receiving groove 20 is possible way of fixing the resist 3 and the first receiving groove 20.
• the second blocking body 4 further includes a push rod 42 connected to the piston portion 41, and the axial direction of the push rod 42 is parallel to a longitudinal axis of the tubular body 2, preferably a push rod.
• the axial direction of 42 is the longitudinal axis of the tubular body 2. Therefore, when the push rod 42 receives an axial thrust, the push rod 42 is adapted to push the piston portion 41 along the longitudinal direction to linearly move the piston portion 41 toward the neck portion 21, thereby reducing the total volume space. 5.
• the push rod 42 when the push rod 42 receives an axial pulling force, the push rod 42 is adapted to pull the piston portion 41 in the longitudinal direction and move linearly away from the neck portion 21, thereby increasing the total volume space 5.
• the push rod 42 and the piston portion 41 may be connected in such a manner that one end of the push rod 42 is integrally formed with the piston portion 41; or, one end of the push rod 42 is hooked on the piston portion 41, and thus, The upward or downward movement of the piston portion 41 can be controlled by the manipulation of the push rod 42. This is a possible embodiment and is not limited thereto.
• the operator can change the capacity distribution state of the total volume space 5 by moving the piston portion 41.
• the operator can push the piston portion 41 to reduce the total volume space 5 or pull the piston portion 41 to increase the total volume space 5.
• the operator can also deform the piston portion 41 by applying force to the piston portion 41, so that the total volume space 5 is reduced or increased, which is also a possible embodiment.
• FIG. 6 it is an embodiment in which a bottom cover 43 is additionally provided in addition to the use of the push rod 42 to push the piston portion 41.
• the second blocking body 4 further includes a bottom cover 43 fixed to the lower edge of the groove of the second receiving groove 22 for limiting the piston portion 41 to be located at the bottom cover 43 and the neck. Between the constrictions 21 .
• the central portion of the bottom cover 43 is a hollow portion 430 for the push rod 42 to pass through the hollow portion 430 and is coupled to the piston portion 41.
• the push rod 42 when the push rod 42 receives an external force, the push rod 42 is adapted to move the piston portion 41 toward the neck portion 21 and/or pull the piston portion 41 to move away from the neck portion 21, thereby adjusting the inside of the centrifuge tube structure.
• the upper and lower displacement of the stratified blood is similar to that of the previous embodiment; at the same time, the present embodiment can limit the possibility that the piston portion 41 is excessively pulled away from the second accommodating groove 22 by the bottom cover 43. .
• FIG. 7 and 8 a schematic cross-sectional view showing the fifth and sixth embodiments of the centrifugal tube structure of the present invention, and is an embodiment in which the bottom cover is used to push the piston portion 41.
• the second blocking body 4 includes a bottom cover 44 or 45, and the bottom cover 44 or 45 is movably disposed at the lower edge of the groove of the second receiving groove 22, so that the piston portion 41 is located at the bottom cover 44. Or 45 is between the necking portion 21.
• the bottom covers 44 and 45 are connected to the piston portion 41.
• the bottom covers 44 and 45 are connected to the piston portion 41 in an integrally formed manner, and are engaged with each other, or are abutted against each other, and are not limited thereto.
• the bottom covers 44, 45 move toward the neck portion 21, the bottom covers 44, 45 push the piston portion 41 to move the piston portion 41 toward the neck portion 21, thereby reducing the total volume space 5; similarly, When the bottom covers 44, 45 are moved away from the necked portion 21, the bottom covers 44, 45 are adapted to pull the piston portion 41 to move the piston portion 41 away from the neck portion 21, thereby increasing the total volume. Space 5.
• the mutual movement between the bottom cover 44 and the second accommodating groove 22 may be such that a surface of the bottom cover 44 is formed with a male thread 221 .
• the surface of the second accommodating groove 22 is formed with a female thread 222.
• the male thread 221 is adapted to cooperate with the female thread 222. Therefore, when the bottom cover 44 receives the force applied in all directions, the bottom cover 44 is adapted to rotate in the axial direction. Move and move along the axis.
• the mutual movement between the bottom cover and the second receiving groove 22 can also move in other ways.
• the bottom cover 45 is a lower edge of the trough body movably disposed in the second accommodating groove 22.
• the bottom cover 45 can receive an axial thrust and move along the longitudinal axis toward the neck portion 21, and the piston portion 41 is pushed by the bottom cover 45 to move the piston portion 41 toward the neck portion 21 to reduce the total
• the bottom cover 45 when the bottom cover 45 receives an axial pulling force to move in a direction away from the neck portion 21 in the longitudinal direction, the bottom cover 45 is adapted to pull the piston portion 41 together, so that the piston portion 41 is biased away from the neck. The direction of the portion 21 is moved to increase the total volume space 5.
• the bottom cover 45 has a negative structure 223, the second receiving groove 22 has a positive structure 224, and the negative structure 223 is adapted to cooperate with the male structure 224, so that the bottom cover 45 can be made opposite to the second receiving groove 22. slide.
• a female thread 222 of the second accommodating groove 22 and a positive structure 224 of the second accommodating groove 22 are all possible movable means of the second accommodating groove 22 of the present invention, and the like. limit.
• FIG. 9 is a cross-sectional view showing a seventh embodiment of the centrifugal tube structure of the present invention.
• the first blocking body 3 of the centrifugal tube structure is a fixed cover body 35, and is fixed to the first receiving groove 20.
• the fixing means 205 is fixed to the first receiving groove 20 by the fixing means 205.
• the second blocking body 4 further includes a push rod 42 connected to the piston portion 41, and the axial direction of the push rod 42 is parallel to the longitudinal axis of the centrifugal tube structure for the user to push and pull.
• FIG. 10 is a cross-sectional view showing an eighth embodiment of the centrifugal tube structure of the present invention.
• the first blocking body 3 of the centrifugal tube structure is a fixed cover 35, which is connected to the first receiving groove 20, and the fixing cover 35 is fixed to the first receiving by the fixing means 205. Slot 20.
• the second blocking body 4 further includes a bottom cover 46.
• the bottom cover 46 is a movable bottom cover, and can be rotated by the user in all directions, so that the bottom cover 46 is along the axial direction. Upon movement, the piston portion 41 is pushed, and/or as a blocking structure that restricts the piston portion 41 from being excessively pulled away from the second accommodating groove 22.
• the second blocking body 4 further includes a push rod 42 connected to the piston portion 41, and the axial direction of the push rod 42 is parallel to the longitudinal axis of the centrifugal tube structure, so that the user can push and pull The push rod 42 moves in the longitudinal direction with the traction piston portion 41.
• FIG. 11 is a cross-sectional view showing a ninth embodiment of the centrifuge tube structure of the present invention.
• the first blocking body 3 of the centrifugal tube structure is a fixing cover 35, and is fixed to the fixing means 205 of the first receiving groove 20, and the fixing cover 35 is fixed to the fixing cover 35 by the fixing means 205.
• the first receiving groove 20 is provided.
• the second blocking body 4 further includes a bottom cover 44 for receiving the user's urging force along the line direction, so that the bottom cover 44 is rotated in the axial direction and moves along the axial direction. Further, the piston portion 41 is pushed to move toward the neck portion 21.
• the centrifuge tube structure disclosed in the present invention makes it easier for the operator to extract the layered solution by designing a neck portion having a narrow cross-sectional area.
• the centrifuge tube structure of the present invention can be designed such that the first blocking body and the first receiving groove are fixed to each other and cannot be relatively moved or separated to ensure that the centrifugal tube structure disclosed in the present invention is disposable and simplified at the same time.
• the structural design of the centrifuge tube structure makes it easier to mass-produce in manufacturing.
• the centrifugal tube structure of the present invention can also be designed such that the bottom cover is fixed at the lower edge of the groove body of the second accommodating groove, so that the piston portion is limited; and the movable member (including the piston portion and the push rod) It is designed to receive an axial force to push the piston portion. In this way, when the operator performs the extraction action, the force can be prevented from being applied in the other direction, and the component force is applied to the centrifuge tube structure. , and the structure of the centrifuge tube is shaken left and right.

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Citations (7)

• 2012
  • 2012-09-10 CN CN201210332630.XA patent/CN103657756A/zh active Pending
• 2013
  • 2013-09-04 WO PCT/CN2013/082940 patent/WO2014036945A1/fr not_active Ceased
  • 2013-09-04 AU AU2013312546A patent/AU2013312546B2/en not_active Ceased

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