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WO2014099985A1 - Détection de pression dans des systèmes d'injection médicale - Google Patents

Détection de pression dans des systèmes d'injection médicale Download PDF

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Publication number
WO2014099985A1
WO2014099985A1 PCT/US2013/075774 US2013075774W WO2014099985A1 WO 2014099985 A1 WO2014099985 A1 WO 2014099985A1 US 2013075774 W US2013075774 W US 2013075774W WO 2014099985 A1 WO2014099985 A1 WO 2014099985A1
Authority
WO
WIPO (PCT)
Prior art keywords
cuff
tubing line
length
pressure sensor
tubing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/075774
Other languages
English (en)
Inventor
Clinton Scott VILKS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACIST Medical Systems Inc
Original Assignee
ACIST Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACIST Medical Systems Inc filed Critical ACIST Medical Systems Inc
Priority to JP2015549583A priority Critical patent/JP2016501629A/ja
Priority to EP13818119.3A priority patent/EP2934623B1/fr
Priority to CN201380066194.9A priority patent/CN104870031B/zh
Priority to HK16104395.5A priority patent/HK1216398B/en
Publication of WO2014099985A1 publication Critical patent/WO2014099985A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49764—Method of mechanical manufacture with testing or indicating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Definitions

  • the present disclosure pertains to medical injection systems and more particularly to pressure sensing therein.
  • Figure 1 is a perspective view of an exemplary medical injection system 100 (the ACIST CVj® system) for delivering a contrast agent into a patient's vascular system for medical imaging.
  • Figure 1 illustrates a first fluid reservoir 132 for supplying a syringe-type positive displacement pump of an injector / pressurizing unit 130, via a fill tubing line 27-F, and an injection tubing line 104 coupled to unit 130 for injection of, for example, a radiopaque contrast agent, into a patient's vascular system via an inserted catheter (not shown), for example, coupled to a patient tubing line 122 at a connector assembly 120 thereof.
  • an inserted catheter not shown
  • Figure 1 further illustrates a second fluid reservoir 138 from which a diluent, such as saline, is drawn by a peristaltic pump 106 through yet another tubing line 128 that feeds into tubing line 122.
  • a manifold valve 124 and associated sensor 1 14 control the flow of fluids into tubing line 122, from pressurizing unit 130 and from tubing line 128.
  • a pressure sensor assembly 126 is shown integrated into line 128 to monitor the patient's blood pressure, in between injections of contrast agent.
  • the aforementioned manifold valve 124 is switched to allow the relatively high pressure flow through line 122 and into the patient's vascular system, and to isolate line 128 and pressure sensor assembly 126 from the flow; then, after the injection, valve 124 is switched to put pressure sensor assembly 126 in fluid communication with patient tubing line 122 to monitor the patient's vascular/hemodynamic pressure.
  • Pressure sensor assembly 126 may be the LogiCal® system available from Smiths Medical International, or the Meritrans®, available from Merit Medical Systems, Inc., both of which are intended for use in a single medical procedure. Alternative means for pressure monitoring in medical injection systems, like system 100, for example, being more robust and/or configured for more flexible integration therein, are desired.
  • a pressure sensor for a medical injection system includes a cuff, a transducer embedded in the cuff, between inner and outer surfaces thereof, and a force transmitting member coupled to the transducer and exposed at the inner surface of the cuff, such that an outer surface of a tubing line, when properly fitted within the cuff, contacts the force transmitting member.
  • a fluid circuit assembly includes the pressure sensor and a specialized tubing line, wherein the specialized tubing line has a limited length of greater compliance than a remainder of the tubing line; the pressure sensor cuff is configured to fit around and enclose the limited length of the tubing line, such that the inner surface of the cuff supports the enclosed second length of the tubing against plastic deformation, when fluid filling the lumen of the tubing line is at pressures significantly greater than atmospheric pressure, for example, during injections.
  • a microprocessor of the pressure sensor is programmed to characterize a transducer signal in response to the force transmitting member, after the cuff is fitted around the tubing line, and while the lumen of the tubing line is open to atmospheric pressure, to detect whether or not the cuff is properly fitted around the tubing line, and/or to determine a characteristic of the tubing line, wherein the characteristic may indicate whether or not the tubing line is suitable for proper function of the pressure sensor cuff therewith.
  • Fitting the cuff around the tubing line may be accomplished by either axially or radially inserting the tubing line into the cuff, the latter being accommodated by a slit formed in the cuff, according to some embodiments.
  • the microprocessor of the sensor may be adapted to send a signal to an injector of the injection system, after detecting the proper tubing line and fit thereof in the cuff, wherein the signal unlocks the injector for operation.
  • Figure 1 is a perspective view of an exemplary medical injection system
  • Figure 2A is a plan view of a fluid circuit assembly for a medical injection system, according to some embodiments.
  • Figure 2B is a cross-section view of a pressure sensor of the assembly, taken through section line B-B of Figure 2A, according to some embodiments;
  • Figure 3A is a plan view of a specialized tubing line for a fluid circuit assembly, according to some alternate embodiments.
  • Figure 3B is an axial cross-section view through a pressure sensor fitted around a length of the tubing line shown in Figure 3A;
  • Figure 4 is a flow chart outlining some methods of the present invention.
  • Figure 2A is a plan view of a fluid circuit assembly 210 for a medical injection system, for example, system 100 of Figure 1 .
  • Figure 2A illustrates assembly 210 including a pressure sensor 200, which is fitted around patient tubing line 122, in proximity to connector assembly 120.
  • Figure 2A further illustrates tubing line 122 including a proximal connector 21 (i.e. a Luer fitting), for example, to connect assembly 210 to the above-described manifold valve 124 of system 100.
  • pressure sensor 200 is employed to measure system pressures, for example, generated by injector 130 ( Figure 1 ), and tubing line 122 has a wall thickness and stiffness to withstand relatively high injection pressures (i.e.
  • line 122 may be formed from nylon-reinforced polyurethane, and has a nominal outer diameter of approximately 0.188 inch (4.78 mm) and a nominal wall thickness of approximately 0.05 inch (1 .27 mm).
  • pressure sensor 200 may be employed to measure both system pressures and physiologic pressures (i.e. blood pressure) of a patient, or just physiologic pressures, in which case, tubing line 122 may include a check valve 22 integrated therein.
  • tubing line 122 is replaced with a specialized tubing line, for example, line 322 of Figure 3A, which will be described in greater detail below.
  • Figure 2B is a cross-section view of assembly 210, taken through section line B-B of Figure 2A.
  • Figure 2B illustrates pressure sensor 200 including a cuff 250, a force transmitting member 216, and a transducer 206 coupled to force transmitting member 216, wherein transducer 206 is embedded between an inner surface 253 and an outer surface 255 of cuff 250.
  • Figure 2B further illustrates force transmitting member 216 exposed at inner surface 253 of cuff 250, and inner surface 253 configured to fit around a length tubing line 122, for example, a length 222 shown in Figure 2A.
  • pressure sensor cuff 250 is sized so that an outer surface 202 of tubing line 122 is in intimate contact with force transmitting member 216, when cuff 250 is properly fitted around tubing line 122; thus, a wall 12 of tubing line 122 transmits, to force transmitting member 216, a pressure of fluid within a lumen 220 of tubing line 122, which is in communication with the patient's vascular system when an inserted catheter (not shown) is connected to tubing line 122 at connector assembly 120.
  • length 222 is between approximately 1 inch and 1 .5 inch (2.5 - 3.8 cm)
  • inner surface 253 of cuff 250 defines a diameter of approximately 0.19 inch (0.48 cm)
  • force transmitting member 216 and transducer 206 are a stainless steel ball/plunger and piezoresistive silicon die, respectively, for example, similar to that employed in the FSS series force sensors of Honeywell (Golden Valley, MN).
  • Force transmitting member 216 in conjunction with transducer 206, generates response signals corresponding to the pressure of fluid in lumen 220, and an electrical lead wire 260 (Figure 2A) may conduct the signals from transducer 206 to a system microprocessor, which may generate plots of blood pressure vs. time, for example, on a display of a control panel, like panel 152 of system 100 ( Figure 1 ).
  • sensor 200 may include means for wireless transmission of the signals, according to methods known in the art.
  • Dashed lines in Figure 2B illustrate an optional slit 240 formed through cuff 250 and a corresponding living hinge 242 formed in an opposing side of cuff 250, which allow for cuff 250 to open for radial insertion of tubing line 122 therein.
  • tubing line 122 may be axially inserted into cuff 250, for example, via arrow X of Figure 2A, so that cuff 250 need not include slit 240 and hinge 242.
  • Figure 3A is a plan view of the aforementioned specialized tubing line 322 for incorporation in a fluid circuit assembly, according to some alternate embodiments, such as assembly 310 of Figure 3B, which is shown in axial cross-section.
  • Figure 3A illustrates tubing line 322 including a first length 351 , which extends from a proximal connector 31 , and a second length 352 which extends between first length 351 and a distal connector 32.
  • Tubing line 322 may be substituted for tubing line 122 in system 100 ( Figure 1 ), wherein proximal connector 31 is coupled to manifold valve 124, and distal connector is coupled to connector assembly 120.
  • Figure 3B illustrates pressure sensor 200 fitted around, and enclosing second length 352 of tubing line 322 such that an outer surface 302 of second length 352 contacts force transmitting member 216 of pressure sensor 200.
  • a wall of first length 351 has a compliance, or stiffness which can withstand relatively high injection pressures without plastic deformation, while a wall of second length has a greater compliance, or lower stiffness, which allows second length 352 to provide a more sensitive/responsive interface for transmitting lower, physiologic pressures of fluid within lumen 320 of tubing line 322 to transducer 206, via force transmitting member 216.
  • cuff 250 of pressure sensor 200 by enclosing an entirety of second length 352, supports the more compliant wall thereof against plastic deformation during relatively high pressure injections.
  • FIG. 3A further illustrates check valve 22 integrated into first length 351 of tubing line 322, according to preferred embodiments, wherein valve 22 blocks back-flow from distal connector 32 and provides a pressure backstop for improved signal response during physiologic pressure monitoring, when connector assembly 120 couples tubing line 322 to a catheter inserted in a patient's vascular system.
  • a thickness of the wall of second length 352 of tubing line 322 may be less than that of first length 351 , to increase the compliance of second length 352.
  • tubing line 322 is formed from the aforementioned nylon-reinforced polyurethane, wherein first length 351 has a nominal wall thickness of approximately 0.05 inch (1 .27 mm) and second length 352 has a nominal wall thickness no greater than approximately 0.01 inch (0.254 mm).
  • a thickness of tubing line 322 along both lengths 351 , 352 may be the same, wherein second length 352 is formed from a more compliant material than first length 351 , for example, from polyurethane without the nylon reinforcement and/or polyurethane of a reduced durometer.
  • an outer diameter of second length 352 is preferably greater than that of first length 351 , for example, as a means for detecting the proper placement of cuff 250 along tubing line 322, as described below.
  • FIG. 4 is a flow chart outlining some methods of the present invention for assembling a fluid circuit of a medical injection system, for example, like system 100.
  • a pressure sensor cuff for example, cuff 250 of sensor 200
  • a tubing line for example, tubing line 122 or 322
  • inserting the length into the cuff for example, either by opening a side slit in a sidewall of the cuff to radially insert the length of tubing line therein, or by axially inserting the length of tubing line into the cuff.
  • the length of the tubing line may be compressed to facilitate insertion into the cuff and then expanded within the cuff to assure that a force transmitting member, for example, member 216, of the pressure sensor contacts an outer surface of the inserted length of tubing line.
  • a transducer signal for example, generated by transducer 206 in response to force transmitting member 216, may be characterized by a microprocessor coupled to the transducer, per step 44, for example, in order to detect whether or not the pressure sensor cuff is properly positioned around the length of the tubing line, and/or whether or not the length of tubing line is a type suitable for proper function of the pressure sensor cuff; that is, whether or not the tubing line has a sufficient outer diameter and/or a compliant enough wall for the transmission of pressure therethrough to the contacting force transmitting member of the pressure sensor.
  • the microprocessor is one dedicated to pressure sensor 200, for example, built into cuff 250; alternately the microprocessor may be one in the same as the aforementioned system microprocessor, for example, being coupled to sensor 200 via electrical lead wire 260. In either case, according to some preferred embodiments, the microprocessor is also coupled to an injector of the injection system, for example, injector 130 of system 100 ( Figure 1 ), in order to send a signal to the injector, after detecting the proper tubing line and fit thereof in the cuff, wherein the signal unlocks the injector for operation.
  • an injector of the injection system for example, injector 130 of system 100 ( Figure 1 )
  • an outer diameter of a more compliant section of the specialized tubing line is preferably larger than a remainder of the tubing line, such that if the pressure sensor cuff is positioned around the stiffer section of the line, for example, first length 351 of line 322, a gap, or clearance between the force transmitting member, at the inner surface of the cuff, and the tubing line prevents transmission of sufficient force from the tubing line to the force transmitting member to prevent detection of a proper fit.
  • detection of too great a tubing compliance may protect against inadvertent reuse of a tubing line which is intended for single use.
  • a baseline pressure for example, zero with respect to atmospheric
  • a signal may be generated by the microprocessor to unlock the injector for operation, preferably after, step 48, in which a catheter, which is inserted within a patient's vascular system, is connected to the tubing line, for example, via connector system 120 ( Figures 1 , 2A).
  • the assembled fluid circuit allows for the monitoring of system pressures and/or the patient's blood pressure, via transmission through the wall of the length of tubing line inserted within the pressure sensor cuff.
  • the above described embodiments of pressure sensor 200 are reusable over a number of medical imaging procedures, since none of the components thereof are exposed to bodily fluids. Furthermore, the above described configurations of pressure sensor 200 allow for positioning and repositioning thereof in a fluid circuit of a medical injection system without concern for introducing air bubbles into the fluid circuit.
  • the aforementioned ball/plunger and piezoresistive silicon die when employed for the force transmitting member and transducer, respectively, form a robust pressure sensor of sufficient range and sensitivity useful for both physiologic and system pressure monitoring (i.e. pressures ranging from approximately 0 psi to approximately 1200 psi).
  • the pressure sensor components have a more limited range and sensitivity tailored to measure relatively high system pressures (i.e. up to 1200 psi), for example, through the wall of a high pressure tubing line (i.e. tubing line 122, as described above).

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un capteur de pression (200) pour un système d'injection médicale, qui comprend un brassard (250), un transducteur (206) intégré dans le brassard et un élément de transmission de force couplé au transducteur et exposé au niveau d'une surface interne du brassard, de sorte qu'une surface externe d'une tubulure (122) d'un circuit de fluide du système, une fois montée à l'intérieur du brassard, se trouve en contact avec l'élément de transmission de force. Une longueur limitée de la tubulure peut avoir une flexibilité supérieure à celle du reste de la tubulure et, dans ce cas, le brassard de capteur de pression s'ajuste autour de la longueur limitée et l'enferme pour la protéger contre la déformation plastique, lorsque les pressions dans la tubulure sont considérablement supérieures à la pression atmosphérique. Le capteur de pression peut détecter si le brassard est correctement ajusté ou non autour de la tubulure et/ou déterminer une caractéristique de la tubulure.
PCT/US2013/075774 2012-12-20 2013-12-17 Détection de pression dans des systèmes d'injection médicale Ceased WO2014099985A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2015549583A JP2016501629A (ja) 2012-12-20 2013-12-17 医療用注入システムの圧力感知
EP13818119.3A EP2934623B1 (fr) 2012-12-20 2013-12-17 Détection de pression pour systèmes d'injection médicals
CN201380066194.9A CN104870031B (zh) 2012-12-20 2013-12-17 医疗注射系统中的压力感测
HK16104395.5A HK1216398B (en) 2012-12-20 2013-12-17 Pressure sensing in medical injection systems

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/721,485 US9220834B2 (en) 2012-12-20 2012-12-20 Pressure sensing in medical injection systems
US13/721,485 2012-12-20

Publications (1)

Publication Number Publication Date
WO2014099985A1 true WO2014099985A1 (fr) 2014-06-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/075774 Ceased WO2014099985A1 (fr) 2012-12-20 2013-12-17 Détection de pression dans des systèmes d'injection médicale

Country Status (5)

Country Link
US (1) US9220834B2 (fr)
EP (1) EP2934623B1 (fr)
JP (1) JP2016501629A (fr)
CN (1) CN104870031B (fr)
WO (1) WO2014099985A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11369739B2 (en) 2013-01-21 2022-06-28 Medline Industries, Lp Method to provide injection system parameters for injecting fluid into patient

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3867190B1 (fr) 2018-10-17 2024-09-18 Pneuma Systems Corporation Pompe volumétrique à base de flux d'air
US12201805B2 (en) 2020-06-29 2025-01-21 Pneuma Systems Corporation Simplified pneumatic volumetric pump using IV drip chamber
US20220118178A1 (en) * 2020-10-20 2022-04-21 Pneuma Systems Corporation Iv gravity delivery monitor

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US5024099A (en) * 1989-11-20 1991-06-18 Setra Systems, Inc. Pressure transducer with flow-through measurement capability
US5031460A (en) * 1989-01-31 1991-07-16 Daikin Industries, Ltd. Transducer for detecting pressure changes in pipes
WO1998054555A1 (fr) * 1997-05-28 1998-12-03 Förderverein Institut für Medizintechnik Dresden e.V. Dispositif pour mesurer et/ou detecter la pression interieure de lumens ou de flexibles
EP1213035A1 (fr) * 2000-12-08 2002-06-12 Hospal International Marketing Management Dispositif pour la mesure de pression comportant une membrane moulée dans une cassette
WO2004061399A2 (fr) * 2002-12-30 2004-07-22 Nxstage Medical, Inc Detecteur de pression pour circuits de fluides
EP1655044A2 (fr) * 2004-11-05 2006-05-10 Nipro Corporation Appareil de purification du sang

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AT374007B (de) * 1980-03-19 1984-03-12 List Hans Messwertaufnehmer zur messung mechanischer groessen an hohlkoerpern
US5097841A (en) 1988-09-22 1992-03-24 Terumo Kabushiki Kaisha Disposable pressure transducer and disposable pressure transducer apparatus
US5808203A (en) 1997-05-12 1998-09-15 Medrad, Inc. Fluid pressure measurement devices
EP2272422B1 (fr) 2001-12-07 2016-05-04 ACIST Medical Systems, Inc. Valve pour fluide qui bloque sa sortie lorsque la pression est eleveé à l'entrée
SE0400330D0 (sv) * 2004-02-12 2004-02-12 Gambro Lundia Ab Pressure sensing
US8631683B2 (en) * 2007-02-06 2014-01-21 Fresenius Medical Care Holdings, Inc. Dialysis systems including non-invasive multi-function sensor systems

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US5031460A (en) * 1989-01-31 1991-07-16 Daikin Industries, Ltd. Transducer for detecting pressure changes in pipes
US5024099A (en) * 1989-11-20 1991-06-18 Setra Systems, Inc. Pressure transducer with flow-through measurement capability
WO1998054555A1 (fr) * 1997-05-28 1998-12-03 Förderverein Institut für Medizintechnik Dresden e.V. Dispositif pour mesurer et/ou detecter la pression interieure de lumens ou de flexibles
EP1213035A1 (fr) * 2000-12-08 2002-06-12 Hospal International Marketing Management Dispositif pour la mesure de pression comportant une membrane moulée dans une cassette
WO2004061399A2 (fr) * 2002-12-30 2004-07-22 Nxstage Medical, Inc Detecteur de pression pour circuits de fluides
EP1655044A2 (fr) * 2004-11-05 2006-05-10 Nipro Corporation Appareil de purification du sang

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11369739B2 (en) 2013-01-21 2022-06-28 Medline Industries, Lp Method to provide injection system parameters for injecting fluid into patient

Also Published As

Publication number Publication date
CN104870031A (zh) 2015-08-26
US20140180084A1 (en) 2014-06-26
EP2934623A1 (fr) 2015-10-28
US9220834B2 (en) 2015-12-29
JP2016501629A (ja) 2016-01-21
HK1216398A1 (en) 2016-11-11
CN104870031B (zh) 2017-04-12
EP2934623B1 (fr) 2017-02-15

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