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WO2014087343A1 - Système de mesure de l'allaitement - Google Patents

Système de mesure de l'allaitement Download PDF

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Publication number
WO2014087343A1
WO2014087343A1 PCT/IB2013/060624 IB2013060624W WO2014087343A1 WO 2014087343 A1 WO2014087343 A1 WO 2014087343A1 IB 2013060624 W IB2013060624 W IB 2013060624W WO 2014087343 A1 WO2014087343 A1 WO 2014087343A1
Authority
WO
WIPO (PCT)
Prior art keywords
breastfeeding
meter system
breast
electrodes
milk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2013/060624
Other languages
English (en)
Inventor
Amir Ben Shalom
Dan OUANOUNOU
Shay GLIKMAN
David Kelly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MOMILK Ltd
Original Assignee
MOMILK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MOMILK Ltd filed Critical MOMILK Ltd
Publication of WO2014087343A1 publication Critical patent/WO2014087343A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0537—Measuring body composition by impedance, e.g. tissue hydration or fat content
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6804—Garments; Clothes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network

Definitions

  • the embodiments disclosed herein relate to a breastfeeding meter system.
  • the system is configured to determine parameters related to breast milk extrusion based on electrical impedance of the breast tissue.
  • a breastfeeding meter system comprising an alternating current (AC) source wired to a first pair of electrodes and a processing unit wired to a second pair of electrodes and a casing encasing the AC source and the processing unit.
  • the electrodes may be configured to be placed on the surface of a breast tissue; and the processing unit may be configured to measure the impedance of the breast tissue.
  • the AC source is configured to produce a current of less than 500 micro amperes. Additionally or alternatively, the AC source is configured to produce a current having a frequency of less than 100 kilohertz.
  • the breastfeeding meter system may further comprise at least one pad situated in at least one portion of the casing configured to contact the surface of the breast tissue.
  • at least one pad surrounds at least one of the electrodes.
  • at least one pad may cover at least one of the electrodes and the pad is conductive.
  • the pad may comprise at least one material selected from the group consisting of a silicone gel, an air-permeable foam and a non-woven fabric.
  • the casing may comprise a clip.
  • the casing may be in the shape of a pendant and attached to a strap.
  • the breastfeeding meter may be incorporated into a nursing bra.
  • the breastfeeding meter system may be configured to be wirelessly connectable to a device comprising a display and a memory unit.
  • a device comprising a display and a memory unit.
  • a device may be selected from the group consisting of a computer, a tablet, a personal digital assistant (PDA) and a smartphone.
  • the device may comprise a bracelet.
  • the processing unit may be configured to measure the impedance of the breast tissue, calculate at least one sample value based on the impedance and generate a breast milk parameter based on the sample value.
  • the sample value is the phase of the impedance.
  • the breast milk parameter may be selected from the group consisting of an amount of milk extruded from the breast, the amount of breast milk in the breast and the rate of breast milk extrusion from the breast.
  • the initiation of breast milk parameter generation is gated by at least one automatic process.
  • the automatic process is the detection of the placement of the electrodes onto the surface of the breast tissue. Additionally or alternatively, the automatic process is the detection of an increase in temperature. Variously, the automatic process may be the detection of a suckling sound
  • the processing unit may be configured to determine the left-breast or right-breast placement of the system.
  • Figures 1A shows a schematic illustration of a breastfeeding meter system.
  • Figure IB shows a schematic illustration of a breastfeeding meter system on a breast surface.
  • Figure 2A shows a schematic illustration of the breastfeeding meter system with a casing.
  • Figure 2B shows a schematic illustration of the breastfeeding meter system with a casing on a breast surface.
  • Figure 2C shows a schematic illustration of the electrodes situated in the casing of the breastfeeding meter system.
  • Figure 2D shows a schematic illustration of the electrodes, with pads, situated in the casing of the breastfeeding meter system.
  • Figure 3 is an illustration of the breastfeeding meter system incorporated into a bra.
  • Figure 4 is an illustration of a breastfeeding meter system communicating wirelessly with a device.
  • Figure 5 is an illustration of the breastfeeding meter system used in the experiments described in Example 1.
  • FIG. 1A-B shows a schematic diagram representing the main components of an embodiment of a breastfeeding meter system 100.
  • the system 100 includes an alternating current (AC) source 110 wired to two electrodes, 130A and 130D.
  • the system 100 further includes a processing unit 120 wired to two electrodes, 130B and 130C.
  • the four electrodes 130A-D contact a breast skin surface 200, such that the alternating current passing between electrodes 130A and 130B, as well as electrodes 130C and 130D, must pass through the breast tissue 200.
  • the two electrodes wired to the processing unit may be configured to measure voltage.
  • the AC source may be configured to produce a current of less than 500 micro amperes (microA).
  • the AC source 110 may further be configured to produce a current having a frequency of less than 100 kilo hertz (KHz).
  • KHz kilo hertz
  • the AC source 110 may be capable of producing a current of varying amplitudes and frequencies.
  • the system 100 may be encased within a casing 300.
  • the casing 300 is configured to fully surround and provide protection for the AC source 110 and the processing unit 120.
  • the casing 300 may allow for the electrodes to be situated on the portion of the casing 300 designated to face the surface of the breast tissue 200.
  • the electrodes 130 may be exposed and contact the surface of the breast tissue 200 directly ( Figure 2C).
  • Each of the electrodes 130A-D may be covered or surrounded by pads 140A-D ( Figure 2D).
  • the casing 300 may include an on/off button.
  • the casing 300 may include a display and a memory unit. Alternatively, the casing may lack a display or a memory unit.
  • the pad may be constructed of a material that is flexible and may form around the contours of the surface of the breast tissue.
  • the pad 140 may cover the electrodes 130 and be conductive. Alternatively, or in addition, the pad 140 may be not conductive and surround the electrode 130. Alternatively, the pad 140 may comprise conductive and non-conductive portions, with the conductive portion being situated against the electrode 130 and the non-conductive portion surrounding the electrode 130.
  • the pad 140 may be present in other portions of the casing 300, where an electrode is not present, but is configured to contact the surface of the breast tissue.
  • the pad 140 may be disposable.
  • the conductive pad 140 may be comprise various materials as required, for example silicone gel, air-permeable foam, non-woven fabric, or a combination thereof.
  • the material conductive pad 140 may be selected for various desirable properties such as electrical conductivity, resistivity, thermal conductivity, water resistance, strength, adhesive properties, cost or the like as well as combinations thereof.
  • the conductive pad 140 may be adhesive.
  • the conductive pad 140 may comprise a self-adhesive silicone gel.
  • the electrodes 130 may be situated in a flexible portion of the casing 300, such that said flexible portion may form around the contours of the surface of the breast tissue.
  • the casing 300 itself may be constructed of a material that is flexible and may form around the contours of the body, such that the pads 140 may be incorporated into the casing 300, with the desired portions of the casing 300 being treated with a conductive material to provide the electrodes 130.
  • the casing 300 may include a clip that allows the system 100 to be placed securely on the surface of the breast tissue 200 by attaching to a piece of the user's attire, such as an item of clothing or jewelry.
  • the casing may be configured to attach to a nursing bra, a blouse, a necklace or the like.
  • the casing 300 may include a strap attachment, such that the casing 300 may be worn as a pendant.
  • the system 100 may be incorporated into an article of clothing.
  • the article of clothing may be a bra.
  • the bra may be a nursing bra.
  • Electrodes 130 and 130' may be wired to a single processing unit, such that measurement of both the left and right breast may be conducted with no need to move the system 100.
  • the location within the bra of the electrodes 130, 130' is not limited to the location shown in Figure 3.
  • the electrodes 130, 130' may be placed at other parts of the bra (and thus other parts of the breast surface) as appropriate.
  • FIG 4 shows a communication device 400 that may be configured to allow a user to control the operation of the system 100, to visualize and store the data gathered by the system 100, and the like.
  • the system 100 may transmit to and receive data from a communication device 400.
  • the data transfer between the system 100 and the communication device 400 may be wireless.
  • Many wireless communication schemes are known in the art.
  • the wireless communication scheme may be Bluetooth, low energy Bluetooth (BTLE), ANT, or the like.
  • the communication device 400 may be a computer, a tablet, a smartphone, a PDA, a watch or the like.
  • the interaction with the system 100 on the device 400 may be mediated by a software application executed on the communication device 400.
  • the communication device 400 may be a dedicated device perhaps including a user interface, display, a processor, a memory unit or the like.
  • the dedicated device may further include a data input mechanism such as a touchscreen, keypad, control panel or the like.
  • the dedicated device may be an accessory, such as a bracelet or a watch.
  • the processing unit 120 is configured to measure the complex impedance of the breast tissue 200, through which the AC generated in the AC source 110 must pass through to reach the processing unit 120.
  • the processing unit 120 is configured to: - Determine the real component (resistance, R) and the imaginary component (reactance, I) of the complex impedance of the breast tissue 200.
  • the sample value may be a parameter derived from the R and I of the complex impedance.
  • the sample value may be derived from the real component R, the imaginary component I, or a combination of the two.
  • the sample value may be the phase ⁇ (theta) of the complex impedance in polar form.
  • sample value may be the magnitude IZI of the complex impedance in polar form.
  • the sample value may be derived from a combination of the phase ⁇ and the magnitude IZI of the complex impedance.
  • Other sample values that may be calculated from the R and I of the complex impedance are also considered.
  • phase ⁇ may be calculated by the formula:
  • Phase ⁇ arctan ((I + Offseti) / (R + Offset R )).
  • the magnitude IZI may be calculated by the formula:
  • IZI ((I + Offseti) 2 / (R + Offset R ) 2 ) 0 5
  • the offsets of Offseti and Offset R may be calculated offline on a database to provide the best results, e.g., offsets that provide the best correlation between the calculated milk output and the actual milk output.
  • Sample values may be obtained, in addition, from other sources.
  • the system 100 may further include a microphone. Characteristic suckling sounds produced by the baby may unlock to the initiation of the sampling period. Suckling may be detected my other means as well. Motion associated by suckling may be detected by an accelerometer. Suckling by the baby, even without breast milk extrusion, may result in characteristic changes in breast tissue impedance.
  • the processing unit may be configured to sample the complex impedance at a defined sampling rate over the course of a sampling period.
  • the processing unit be configured to batch-calculate the sample values after the termination of the sampling period.
  • processing unit may be configured to calculate the sample value(s) during the sampling period ("live mode") at a defined calculation rate.
  • the processing unit may create one or more data arrays, each data array being a series of one sample value collected over the sampling period.
  • the sampling rate may be, e.g. about O. lHertz (Hz), about 0.2 Hz, about 0.25 Hz, about 0.3 Hz, about 0.4 Hz, about 0.5 Hz, about 0.6 Hz, about 0.75 Hz, about 1 Hz, about 2 Hz, about 3 Hz, about 4 Hz, about 5 Hz, between 0.5 and 2 Hz, or between 0.1 Hz and 5 Hz.
  • the sampling rate is 1 Hz.
  • the calculation rate may be the same or less frequent than the sampling rate and may be, e.g., about 0.01 Hz, about 0.02 Hz, about 0.033 Hz, about 0.05 Hz, about 0.1 Hz, about 0.2 Hz, about 0.25 Hz, about 0.3 Hz, about 0.4 Hz, about 0.5 Hz, about 0.6 Hz, about 0.75 Hz, about 1 Hz, about 2 Hz, about 3 Hz, about 4 Hz, about 5 Hz, between 0.5 and 2 Hz, or between 0.1 Hz and 5 Hz.
  • the calculation is 0.033 Hz.
  • the complex impedance of biological tissue may vary with the frequency of the applied alternating current.
  • the AC source 110 may be configured to apply the AC at a variety of frequencies.
  • the frequency of the applied AC may be set in a calibration step that determines the AC frequency providing sample values that change most robustly with milk extrusion, and selects that AC frequency for use during the sampling period.
  • multiple AC frequencies may be sampled over the course of the sampling period.
  • the sampling period may be started and stopped manually by the user, perhaps via a user interface. Alternatively or in combination, the sampling period may be started and stopped automatically through various measures, as described below.
  • the sample values may be filtered with a linear filter.
  • the sample values may be filtered with a non- linear filter.
  • Various forms of linear and non- linear filtering processes are known in the art.
  • steep changes in the sample values may be caused by electrode movement or other causes not dependent on the amount of milk in the breast tissue.
  • the processing unit may be configured to identify such jumps of the sample values. If there are two consecutive jumps in opposite direction, the sample values between them may be removed from the data array. If there is a single increasing jump, the jump may be compensated for by reducing all the sample values after the jump by the jump amplitude. If there is a single decreasing jump, the jump may be compensated for by increasing all the sample values after the jump by the jump amplitude.
  • the relationship between the sample value(s) and the breast milk parameter(s) may be characterized by a linear function, a parabolic function, a polynomial function, or the like.
  • the function characterizing the relationship between the sample value(s) and the breast milk parameter(s) may be variable over time, e.g., the function may be weighted at a certain level at the beginning of a breast milk extrusion session, and the weighting of the function may change over the course of the session.
  • a breast milk parameter may be based on a relationship to multiple sample parameters.
  • sample parameters may be those based solely on one or more aspects of the measured impedance of the breast tissue, or a combination of breast tissue impedance and other factor, such as suckling motion measured by, e.g., an accelerometer.
  • the breast milk parameter may be any parameter related to breast milk produced in the breast tissue being assayed by the system, being relatable to sample value(s).
  • the breast milk parameter may be based on a single sample value (or an average of multiple sample values) an amount of milk present in a breast tissue 200.
  • the breast milk parameter may be based on a change in the sample value from one point to another: an amount of milk that has been extruded from the breast (through breastfeeding, pumping, or any other method) over a defined start time and finish time.
  • the amount of milk extruded may be expressed as volume of liquid, e.g., milliliters.
  • the breast milk parameter may be based on rate of change in the sample value over time: the rate of milk flow.
  • a related parameter is the starting or termination of milk flow.
  • the transition of the rate of milk flow from zero to non-zero may indicate the beginning of milk flow, and the transiting of the rate of milk from non-zero to zero may indicate the termination of milk flow.
  • the breast milk parameter may be in standard units of measurement.
  • the amount of milk may be expressed in, e.g., milliliters.
  • the rate of milk extrusion may be expressed in, e.g., milliliters per second.
  • the value may be expressed by an arbitrary value (for example - a range from one to ten, a color code, and the like).
  • processing unit may be configured to batch-calculate the breast milk parameter(s) after the termination of the sampling period.
  • processing unit may be configured to calculate the breast milk parameter(s) along with the sample value(s) during the sampling period ("live mode") at the defined calculation rate.
  • the amount of milk output may be compared with the pattern of suckling, as determined by, e.g., an accelerometer.
  • the comparison may provide further breast milk parameters, such as identifying when a reduction in the rate of milk output is due to the baby stopping the suckling activity or the baby engaging in non-productive suckling activity.
  • the conversion from the sample value to the breast milk parameter may be adjusted based on one or more calibration factors to yield the breast milk parameter in said standard unit of volume, e.g., in milliliters.
  • At least one of the calibration factor(s) may be a value based on one or more biological properties of the nursing woman, e.g., age, ethnicity, weight, height, body-mass index, body fat percentage, breast size, and the like.
  • At least one of the calibration factors may be determined for sampling session, based on all or a portion of the sample values gathered from a sampling session. Both empirical and computational calibration methods may a yield unique calibration factor per session.
  • At least one of the calibration factors may be a predetermined calibration factor applied to all calculations independent of the user, e.g., based on previously obtained measurements from a test population comparing one or more sample values to actual milk output.
  • the initiation of breast milk parameter generation is gated by at least one automatic process, some of which are described below.
  • the processing unit 120 may be configured to automatically determine correct electrode 130 placement on the surface of the breast.
  • the processing unit 120 may compare the measured impedance against a pre-determined range of impedances, such that the sampling period is prevented from starting, or is paused, when the impedance is above or below said pre-determined range.
  • the system 100 may further include a temperature sensor. Accordingly, an increase in temperature may signal the proximity of a baby and unlock the initiation of the sampling period.
  • the system 100 may further include a microphone. Characteristic suckling sounds produced by the baby may unlock to the initiation of the sampling period. Suckling may be detected my other means as well. Motion associated by suckling may be detected by an accelerometer. Suckling by the baby, even without breast milk extrusion, may result in characteristic changes in breast tissue impedance.
  • the system 100 may by capable of automatically determining whether the breast it is placed on is the left breast or the right breast. Such a determination may be achieved through monitoring the electrical signals produced by cardiac activity.
  • One or more of the electrodes 130 may periodically measure passive electrical signals (without the injection of AC) to monitor electrical signals from cardiac activity. Because the heart is located towards the left side of the chest, cardiac electric signals will be stronger (e.g., in amplitude) when the system 100 is placed on the left breast compared to when the system is placed on the right breast. Thus, comparing the cardiac signals to system placement (left vs. right) or to pre-determined values allows the system 100 to determine left breast or right breast placement automatically.
  • the nursing mothers are connected to four electrodes on each breast (KendallTM. Arbo H124SG).
  • the electrodes are connected to a metering device, which is connected to a laptop computer running an analysis software (Analog DevicesTM, AD5933 EVAL).
  • the mother is also provided with a breast milk pump attached to a bottle receptacle having a measuring scale (in milliliters).
  • the electrodes are attached to the breasts of the nursing mother, and the impedance of the breast tissue is measured at regular intervals, e.g., every minute or 30 seconds, with the pump turned off, for an initial period (e.g., 2.5 minutes) to measure baseline.
  • the nursing mother turns on the pump.
  • the mother uses a logging program to enter the milk quantity pumped whenever a clear reading of the from the pump's bottle is available (typically at 10 ml intervals, as marked on the bottle), with the logging program automatically logging the time of the volume measurement entry.
  • the mother also logs special events during the pumping that may influence the bioimpedance measurement, such as coughing, drinking, sudden movement, etc., and noting the time of such entries.
  • the bioimpedance measurement continues until the mother has no more milk to pump.
  • Another period (e.g., 2.5 minutes) of post-pumping baseline bioimpedance is measured following the end of pumping. The process is then repeated with the second breast, when possible.
  • This experimental setup allows a comparison of how well the measured milk output matched with various calculated milk outputs, for example, a first calculated milk output based on be the phase ⁇ (theta) of the impedance of the breast tissue in polar form and a second calculated milk output based on the magnitude IZI of the impedance of the breast tissue in polar form.
  • the calculated milk output based on the phase of the impedance matches the measured milk output better than the calculated milk output based on the magnitude of the impedance.
  • the magnitude-based calculated milk output is more susceptible to noise.
  • the term “about” refers to at least ⁇ 10 %.
  • the terms “comprises”, “comprising”, “includes”, “including”, “having” and their conjugates mean “including but not limited to” and indicate that the components listed are included, but not generally to the exclusion of other components. Such terms encompass the terms “consisting of and “consisting essentially of”.
  • composition or method may include additional ingredients and/or steps, but only if the additional ingredients and/or steps do not materially alter the basic and novel characteristics of the claimed composition or method.
  • a compound or “at least one compound” may include a plurality of compounds, including mixtures thereof.

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  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

La présente invention concerne un système de mesure de l'allaitement qui comprend une source de courant alternatif (AC) raccordée par câble à une première paire d'électrodes et une unité de traitement raccordée par câble à une seconde paire d'électrodes et un boîtier renfermant la source de courant alternatif et l'unité de traitement. Les électrodes peuvent être placées sur la surface d'un tissu mammaire et l'unité de traitement peut mesurer l'impédance du tissu mammaire.
PCT/IB2013/060624 2012-12-05 2013-12-04 Système de mesure de l'allaitement Ceased WO2014087343A1 (fr)

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US61/733,582 2012-12-05

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CN107106022A (zh) * 2014-09-16 2017-08-29 医疗探索Nc7公司 用于评估从乳房挤出的乳汁体积的系统、装置和方法
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WO2020025337A1 (fr) 2018-08-02 2020-02-06 Coroflo Limited Dispositif de mesure de volume d'allaitement basé sur micro-capteur
US10702200B2 (en) 2014-11-04 2020-07-07 Stichting Imec Nederland Method for monitoring incontinence
US10709372B2 (en) 2014-11-04 2020-07-14 Stichting Imec Nederland System for monitoring incontinence
CN113884549A (zh) * 2020-07-02 2022-01-04 浙江大学 一种生物组织介电谱测量电极夹具
WO2023004099A1 (fr) * 2021-07-22 2023-01-26 Nfant Labs Llc Système et procédé de mesure de la production de lait maternel
WO2025099724A1 (fr) * 2023-11-09 2025-05-15 Bia Med Ltd. Dispositif et procédé de surveillance d'un ou de plusieurs paramètres d'allaitement

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US20100292604A1 (en) * 2008-01-22 2010-11-18 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Method and device for monitoring breastfeeding

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US20100217148A1 (en) * 2007-11-08 2010-08-26 Inolact Ltd. Measuring Fluid Excreted from an Organ
US20100292604A1 (en) * 2008-01-22 2010-11-18 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Method and device for monitoring breastfeeding

Cited By (19)

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JP2020124611A (ja) * 2014-09-16 2020-08-20 エクスプロラメッド・エヌシー７・インコーポレイテッドＥｘｐｌｏｒａｍｅｄ Ｎｃ７， Ｉｎｃ． 胸から圧搾された母乳量を査定するためのシステム
US11883185B2 (en) 2014-09-16 2024-01-30 Willow Innovations, Inc. Systems, devices and methods for assessing milk volume expressed from a breast
CN107106022A (zh) * 2014-09-16 2017-08-29 医疗探索Nc7公司 用于评估从乳房挤出的乳汁体积的系统、装置和方法
EP3193707A4 (fr) * 2014-09-16 2018-03-14 ExploraMed NC7, Inc. Systèmes, dispositifs et procédés d'évaluation de volume de lait exprimé à partir d'un sein
JP7042300B2 (ja) 2014-09-16 2022-03-25 ウィロー・イノベイションズ・インコーポレイテッド 胸から圧搾された母乳量を査定するためのシステム
US11089991B2 (en) 2014-09-16 2021-08-17 Willow Innovations, Inc. Systems, devices and methods for assessing milk volume expressed from a breast
EP3590420A1 (fr) * 2014-09-16 2020-01-08 ExploraMed NC7, Inc. Systèmes, dispositifs et procédés d'évaluation de volume de lait exprimé à partir d'un sein
CN112493989A (zh) * 2014-09-16 2021-03-16 威洛创新股份有限公司 用于评估从乳房挤出的乳汁体积的系统、装置和方法
US10702200B2 (en) 2014-11-04 2020-07-07 Stichting Imec Nederland Method for monitoring incontinence
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