WO2014051040A1 - Windowed-catheter fastening patch - Google Patents

Description

Window fixing catheter fixing material

The present invention relates to an improvement in a patch for fixing a catheter with a window in order to stably hold a puncture portion of the catheter.

Conventionally, a puncture portion into which a catheter has been inserted has been covered with a dressing formed of a flexible plastic film. Thereby, while maintaining the state of a puncture part stably, it prevented from being contaminated with bacteria etc. from the outside.
In this dressing, an adhesive layer is provided on one surface of a flexible plastic film reinforced with a carrier film, and the adhesive layer is covered with release paper. In this dressing, the release paper is peeled off and attached to the puncture portion with an adhesive layer, and then the carrier film is peeled off.

In such dressings, since the carrier film is used as a support for the adhesive material, it usually has a rigid thickness. For this reason, it has been difficult to fix the puncture portion of the catheter when affixed, and the risk of liquid leakage has increased, and it has often been difficult to affix to the puncture portion when used.

Therefore, a surgical tape or the like is separately prepared in addition to the dressing and the catheter tube is fixed. However, affixing both the dressing material and the surgical tape has a drawback that the work is complicated.
For these reasons, dressing has been proposed in which a window is formed in the center of a nonwoven fabric provided with an adhesive layer on one side. On the pressure-sensitive adhesive layer side of the nonwoven fabric, an absorbent fiber sheet and a non-adhesive perforated polyethylene film are sequentially laminated on the peripheral edge of the window and covered with release paper. And the other window of the said nonwoven fabric has covered the window part of the center with the urethane film which has an adhesive layer. This dressing is effective in that the tube of the catheter can be fixed and the state at the puncture site can be seen. (Patent Document 1)

US Pat. No. 6,124,520

In the various dressings described above, rubber-based pressure-sensitive adhesives and the like have been used for the pressure-sensitive adhesive layer. However, acrylic pressure-sensitive adhesives that are less irritating to the skin are gradually being used.
The acrylic pressure-sensitive adhesive is effective because of its low irritation to the skin, and certain breathability and moisture permeability can be obtained even when an acrylic pressure-sensitive adhesive layer is formed on the urethane film. However, it is necessary to further reduce the irritation to the skin at the puncture site, and better air permeability and moisture permeability have been demanded. However, it is still difficult to obtain a suitable one. .

According to the research of the present inventors, it was found that a polyurethane film provided with a polyurethane pressure-sensitive adhesive layer can obtain better air permeability and moisture permeability than conventional ones. It was found that it can be applied.
However, since the polyurethane adhesive generally has a lower adhesive strength than the acrylic adhesive, it is not suitable for reliably maintaining the fixed state. In addition, when the urethane film provided with such a polyurethane pressure-sensitive adhesive layer is pasted so as to cover the window portion of the nonwoven fabric provided with the window portion, sufficient adhesive force cannot be obtained for the nonwoven fabric, Since the urethane film was easily peeled off from the nonwoven fabric, only insufficient materials for dressing and patch were obtained.

Even if the polyurethane film is provided with a polyurethane adhesive layer on the urethane film, the polyurethane film adhesive of the urethane film is well applied to the nonwoven fabric when the surface of the nonwoven fabric to which the polyurethane film is applied is smoothed. It comes to stick. And even if it was a comparatively narrow sticking area, it did not peel off easily, it discovered that it functions sufficiently as a sticking material, and can obtain favorable air permeability and moisture permeability. And based on such knowledge, it came to complete this invention.

This invention prepares the window part sheet | seat which formed the window part in the nonwoven fabric sheet which provided the adhesive layer on the one surface of the nonwoven fabric, and provided the polyurethane adhesive layer on the one surface of the urethane film. This window sheet is pasted on the other side of the nonwoven fabric so as to cover the window section, and a windowed catheter fixing patch is obtained. The other surface of the nonwoven fabric to which the polyurethane adhesive layer provided on the urethane film is attached has a smooth surface roughness of 7 to 20 μm.
The surface of the nonwoven fabric on the other side of the nonwoven fabric should have a coefficient of dynamic friction with respect to the cotton fabric of 0.1 to 1.0.
Further, the moisture permeability of the nonwoven fabric sheet and ^{5,000 ~ 13,000g / m 2 · 24hr} , preferably when the moisture permeability of the window sheet ^{2,000 ~ 5,000g / m 2 · 24hr} .

In the present invention, the puncture part such as a catheter can be reliably covered and protected by the urethane film provided with the polyurethane pressure-sensitive adhesive layer covering the window part of the nonwoven fabric sheet as described above. Moreover, since the state of the puncture part can be seen through from the window part, the state of the affected part can be observed. Furthermore, since good air permeability and moisture permeability can be obtained, it is less likely that the affected area gets muddy and worsens the situation. And even if this urethane film is a comparatively narrow area on a nonwoven fabric, it is reliably stuck and there is no danger that it peels off during use. Moreover, since the nonwoven fabric sheet has air permeability and moisture permeability, and has appropriate stretchability, it does not place a burden on the skin.

It is a top view which shows the Example of this invention. FIG. 2 is a sectional view taken along line AA in FIG. 1. It is explanatory drawing which shows the use condition of what is shown in FIG.

Various fibers such as natural fibers, synthetic fibers, regenerated fibers, and appropriate combinations thereof can be used for the non-woven fabric 2 that forms the main body of the patch 1 for fixing a catheter with a window in the present invention. For example, an acrylic nonwoven fabric, a polyamide nonwoven fabric, a polyester nonwoven fabric, a polyurethane nonwoven fabric, and the like can be used. Use of a polyurethane nonwoven fabric is often preferable from the viewpoint of moderate stretchability and familiarity with the skin surface.
The basis weight of the nonwoven fabric is not particularly limited, and may be within the range of the basis weight of nonwoven fabrics generally used as a base material for pressure-sensitive adhesive tapes, but is preferably about 50 to 100 g / m ² . The thickness of the nonwoven fabric is usually 100 to 500 μm.

The nonwoven fabric 2 may have a 30% tensile load in the longitudinal direction and the width direction of about 0.8 to 3.6 N / 15 mm, preferably 1.0 to 3.2 N / 15 mm. In this way, as will be described later, familiarity with the skin is good, and less stress is applied to the affected affected part following the movement of the body.
According to JIS Z0237, this 30% tensile load is obtained by stretching the test piece (nonwoven fabric) by 30% using an Instron type tensile tester in an atmosphere of 23 ° C. and 50% RH. Measured and converted into a 15 mm width.

A non-woven fabric sheet 4 is formed by providing an adhesive layer 3 on one surface of the non-woven fabric 2. Various adhesives such as natural rubber, synthetic rubber, acrylic, vinyl ether, and silicone can be used as the adhesive. Since the nonwoven fabric sheet 4 provided with the pressure-sensitive adhesive layer 3 is affixed to the skin as will be described later, the pressure-sensitive adhesive provides sufficient adhesion to the skin surface, has little irritation to the skin, and is transparent. Those that are expected to have some moisture are good. For these reasons, it is often preferable to use an acrylic adhesive.

As the acrylic pressure-sensitive adhesive, the main component is a homopolymer or copolymer of a long chain (meth) acrylic acid ester monomer having about 4 to 12 carbon atoms such as butyl acrylate, 2-ethylhexyl acrylate, isononyl acrylate, or ( It is preferable to use a (meth) acrylic acid ester monomer. In addition, 2 to 50% by weight of one or more other copolymerizable monomers such as (meth) acrylic acid, vinyl acetate, styrene, vinyl pyrrolidone, acrylamide, hydroxyethyl acrylate, hydroxypropyl acrylate and the like as main components. Examples thereof include a copolymer obtained by copolymerization within the range.
The thickness of the pressure-sensitive adhesive layer 3 is usually about 10 to 200 μm, preferably 20 to 100 μm.

Such a non-woven sheet 4 is usually in the form of a rectangle with round corners (3 cm × 5 cm) to (20 cm × 24 cm), but it may be square, oval, round or any other suitable shape depending on the application. Can do.

A part of this nonwoven fabric sheet 4 is usually cut off at a substantially central portion so that the affected part can be seen through, as described later, such as a rounded hexagon, ellipse, circle, etc. An appropriately sized window 5 is provided.

The window portion 5 formed on the nonwoven fabric sheet 4 is covered with a window portion sheet 6.
The window sheet 6 has a polyurethane adhesive layer 8 formed on one surface of a urethane film 7. The polyurethane adhesive layer 8 is attached to the other side 9 of the nonwoven fabric sheet 4 where the adhesive layer 3 is not provided so as to cover the window portion 5.

The window sheet 6 can reliably cover the window section 5 and preferably has an area as small as possible.
Although the window sheet 6 uses the urethane film 7 as a support in order to make the puncture part visible from the outside, the moisture permeability is lower than that of the nonwoven fabric. If the entire surface of the nonwoven fabric sheet 4 is covered with the window sheet 6, the moisture permeability of the entire patch is unnecessarily low. In addition, when applied to uneven skin, wrinkles may occur or tension may be felt due to the difference in flexibility between the nonwoven fabric and the film. For this reason, the window sheet should be shaped so as to cover the nonwoven fabric up to about 1 to 2 cm beyond the frame edge of the window, and about 2 to 4 times the area of the window. What has an area is preferable. The shape of the window sheet 6 may be similar to that of the window part, or may be rectangular, circular, or other appropriate shape.

As described above, the window sheet 6 is arranged on the upper surface of the nonwoven fabric sheet 4 on the side opposite to the pressure-sensitive adhesive layer 3 to cover the frame edge forming the window provided in the nonwoven fabric sheet. Therefore, even if the nonwoven fabric sheet frequently rubs against the fingertips or clothes, the nonwoven fabric does not squeeze out from the frame edge of the window portion, and the appearance does not deteriorate.

The other side 9 of the nonwoven fabric sheet 4 to which the window sheet 6 is attached has a surface roughness of 6 to 24 μm, preferably 7 to 20 μm, more preferably 9 to 15 μm, and even more preferably 11 to 13 μm. It is formed in such a smooth state. If the surface roughness is too large, the adhesiveness with the window sheet is deteriorated. On the other hand, if the surface roughness is too small, the slipperiness between the hand, the cloth and the outside objects that are in contact with each other at the time of use deteriorates, making it difficult to use.

In order to form the other side 9 of the nonwoven fabric sheet 4 in a smooth state, it can be performed by pressing, heating press, ironing, and other various methods. For example, the raw material of the nonwoven fabric 2 on which the pressure-sensitive adhesive layer 3 has not yet been formed is calendered to obtain a smooth state having the above-described surface roughness.

(Measurement of surface roughness)
The above-mentioned surface roughness is obtained by measuring and displaying the surface arithmetic average roughness Sra using “SURFCORDER ET4000A” (manufactured by Kosaka Laboratory Co., Ltd.) which is a surface roughness meter. The measurement was performed under the conditions of an X measurement length of 4 mm, an X feed speed of 0.5 mm / s, a Y feed pitch of 30 μm, and a Y line number of 100, with a Z magnification of 1000.

Since the polyurethane adhesive layer 8 provided on one surface of the urethane film 7 in the window sheet 6 has a low adhesive action, it is difficult to apply it to the surface of a normal nonwoven fabric. Easy to peel off. However, when the surface roughness of the nonwoven fabric is made smooth as described above, the polyurethane pressure-sensitive adhesive layer 8 can also be reliably attached and can be used without being easily peeled off.

And the surface of the other surface side 9 of the said nonwoven fabric sheet 4 is good to form a low dynamic friction coefficient so that it may slip easily. The dynamic friction coefficient is about 0.1 to 1.0, preferably 0.4 to 1.0, and more preferably 0.5 to 1.0 in terms of the dynamic friction coefficient with respect to the cotton cloth.
Further, the surface of the urethane film 7 of the window sheet 6 is 0.1 to 0.8, preferably 0.4 to 0.8, more preferably 0.5 to 0.7 in terms of the coefficient of dynamic friction with respect to the cotton cloth. Then, it is favorable in terms of slipperiness. The surface of the window portion sheet 6 may have a dynamic friction coefficient comparable to that of the nonwoven fabric sheet 4, and the feeling of discomfort regarding the feeling of the entire patch is reduced.

(Measurement of dynamic friction coefficient)
The measurement of the dynamic friction coefficient allows the surface slipperiness to be observed, and was measured based on JIS K7125 “Plastic-Film and Sheet Friction Coefficient Test Method”.
The tester uses an Instron type tensile tester, and a test piece is attached so that wrinkles do not enter the horizontal plate. Adhere a cotton cloth so that wrinkles do not enter the bottom of the 200 ± 2 g weight. Place the weight with the cotton cloth on the test piece, hang a thin metal wire on the hook attached to the weight, and sandwich the other with the grip of the tensile tester. The weight is moved through the pulley in the horizontal direction at a moving speed of 100 mm / min and the moving distance is 50 mm. The friction force during this period is recorded, and the friction force shown while the weight is moving is defined as the dynamic friction force. The dynamic friction coefficient is obtained by dividing the obtained average dynamic friction force by the vertical load due to the weight.

Thus, the window portion sheet 6 is securely attached to the nonwoven fabric sheet 4 so as to cover the window portion 5, and has an adhesive strength of about 0.65 to 2.5 N / 10 mm, preferably 1.0 to 2.0 N / 10 mm, and more preferably 1.0 to 1.5 N / 10 mm.
This adhesive force was measured by a T-type peel test. The bonded specimen was cut to a width of 10 mm, and the nonwoven fabric sheet 4 was sandwiched between the lower grip and the window sheet 6 was sandwiched between the upper grips. The force when the test piece was peeled off while maintaining almost horizontal at a speed of 300 mm per minute was determined as the adhesive strength.

The nonwoven fabric sheet 4 and the window sheet 6 preferably have high moisture permeability, but the nonwoven fabric sheet 4 has a moisture permeability of about 3,000 to 15,000 g / m ² · 24 hr, preferably 5,000 to 13,000 g. / ^m to 2 · 24 hr or, more preferably to ^{7,000 ~ 12,000g / m 2 · 24hr} , more preferably it may be in the ^{9,000 ~ 11,000g / m 2 · 24hr} .
Further, the window sheet 6 and the polyurethane adhesive layer 8 provided on the urethane film 7, a 2,000 ~ 5,000g ^/ m 2 · 24hr as moisture permeability, ^2-preferably 3,000 ~ 4,000 g / ^m 24 hours can be obtained.

The urethane film 7 used for the window sheet 6 is preferably made of polyester or polyether polyurethane. Further, the film should not swell even when contacted with water, treatment liquid, or other liquid, and a polyether polyurethane film is particularly preferable.
The thickness of the polyurethane film is usually preferably 10 to 50 μm.

(Moisture permeability test)
The moisture permeability was measured as the amount of water vapor that passes through a test piece of unit area in a certain time.
The mass of water vapor that passes through the test piece in 24 hours when the relative humidity of the space on one side separated by the test piece is 90% and the other side space is kept dry by a hygroscopic agent in a 40 ° C. atmosphere. (G) was measured and converted per 1 m ^{2 of} the test material.
The measurement was performed according to the following procedure according to the condition B of JIS Z-0208. A round test piece having a diameter about 10 mm larger than the inner diameter of the cup was put on a cup containing about 15 g of calcium chloride hygroscopic agent, and further, a rubber packing and a ring were put on and screwed to prevent the test piece from shifting.
After measuring the total mass of the test piece, it was placed in a constant temperature and humidity chamber under a 40 ° C., 90% RH atmosphere, and the change in mass per fixed time was measured. The moisture permeability was determined according to the following equation.
Moisture permeability (g / m ² · 24 hr) = W x 24000 / S
[In the formula, S represents a moisture permeable area (cm ² ), and W represents an increase in mass per hour (g / hr). ]

The pressure-sensitive adhesive layer 3 and polyurethane pressure-sensitive adhesive layer 8 side of the window-fixing patch 1 for catheter fixation are usually covered with a release paper 10 having the same size as or larger than that of the nonwoven fabric sheet 4 to cover the pressure-sensitive adhesive layer. You should protect it. As the release paper, polylamination paper or polyester film or the like whose release agent is treated with silicone on one side or both sides is usually used. One or more release papers may be used so as to cover the pressure-sensitive adhesive layer, and 3 sheets are particularly preferable.
In the figure, it is divided into three parallel parts: a central part 11 covering the entire adhesive layer of the window part 5, a right part 12, and a left part 13, and can be peeled off sequentially. ing.

When this windowed catheter fixing patch 1 is used, in the illustrated case, the central portion of the release paper 10 formed larger than the windowed catheter fixing patch 1 and divided into three parallel sheets is used. 11 is peeled off. The exposed pressure-sensitive adhesive layers 3 and 8 are accurately applied to the skin surface 18 while watching the puncture portion 17 of the catheter 16 through the window sheet 6 of the urethane film of the window portion 5. Thereafter, the right side portion 12 and the left side portion 13 of the release paper are peeled off, and the remaining nonwoven fabric sheet 4 is attached to the skin surface 18 around the puncture portion 17. Thus, the fingertip can be applied without touching the adhesive layer, and the catheter 16 can be fixed hygienically.

The catheter 16 positioned outside the window-fixing patch 1 for catheter fixation is appropriately fixed to the skin surface with an adhesive tape 19 preferably made of the same nonwoven fabric sheet 4 as necessary. be able to. Such an adhesive tape 19 covered with release paper can be enclosed in the packaging when the windowed catheter fixing patch 1 is packaged.

When the windowed catheter fixing patch 1 is attached, the catheter 16 located at the puncture portion 17 is fixed by the polyurethane adhesive layer 8 of the window portion sheet 6 covering the window portion 5. The window sheet 6 can ensure good air permeability and moisture permeability while preventing invasion of various bacteria. Therefore, the affected part can be kept in a suitable state. Moreover, the catheter 16 extended from the puncture part 17 by the nonwoven fabric sheet 4 can be hold | maintained in the stable stationary state.

(Example 1)
A polyurethane nonwoven fabric having a thickness of 300 μm and a surface roughness of “26 μm” is pressed to a surface roughness of “11 μm”, a 30% tensile load of 2.11 N / 15 mm in the width direction and 3.06 N / 15 mm in the longitudinal direction. A polyurethane nonwoven fabric 2 is prepared. An acrylic foam pressure-sensitive adhesive layer 3 having a thickness of 30 μm is formed on one surface of the nonwoven fabric, and is formed into a round rectangle with a corner of 8 cm long × 11 cm wide. And the corner 5 hexagonal window part 5cm of length 5cm x width 4.5cm was formed in the center part.
Next, a rectangular window sheet 6 having a length of 8 cm and a width of 5 cm, in which a polyurethane adhesive layer 8 having a thickness of 30 μm is formed on one surface of the urethane film 7 having a thickness of 20 μm, is prepared. Attached to the other surface side 9 (surface roughness of 11 μm) of the nonwoven fabric 2 so as to cover the window portion 5 was fixed, and a catheter fixing patch 1 with a window was obtained. The polyurethane pressure-sensitive adhesive layer used had a characteristic that the adhesive strength to bakelite (180 degree peeling) was 1.44 N / 15 mm. Both the pressure-sensitive adhesive layers are covered with a release paper 10 that is larger than the adhesive patch divided into three parts of a central part 11, a right part 12, and a left part 13. (See Figure 1)

(Example 2)
A polyurethane nonwoven fabric having a thickness of 300 μm and a surface roughness of “26 μm” is pressed to a surface roughness of “13 μm”, a 30% tensile load is 1.19 N / 15 mm in the width direction and 1.63 N / 15 mm in the longitudinal direction. The polyurethane nonwoven fabric 2 is used. Other than that, the window-fixing patch 1 was used in the same manner as in Example 1.

(Example 3)
A polyurethane nonwoven fabric having a thickness of 300 μm and a surface roughness of “26 μm” is pressed to a surface roughness of “13 μm”, and a 30% tensile load is 1.71 N / 15 mm in the width direction and 2.26 N / 15 mm in the longitudinal direction. Polyurethane nonwoven fabric 2 was used. And the adhesive layer 3 was formed with the acrylic adhesive whose adhesive force is higher than the adhesive of Example 1. FIG. Other than that, the window-fixing patch 1 was used in the same manner as in Example 1.

(Comparative Example 1)
Polyurethane nonwoven fabric 2 having a thickness of 300 μm and a surface roughness of “26 μm” that is not subjected to surface smoothing, a 30% tensile load in the width direction of 2.23 N / 15 mm, and a longitudinal direction of 2.86 N / 15 mm is used. did. The nonwoven fabric sheet 4 is formed with the same acrylic adhesive as the Example 3 for the adhesive layer 3, and the acrylic adhesive layer is provided instead of the polyurethane adhesive layer as the adhesive layer 8 of the window portion sheet 6. Others were the same as in Example 1 and used as a catheter fixing patch with a window.

(Comparative Example 2)
A window sheet 6 using the same polyurethane nonwoven fabric 2 and acrylic pressure-sensitive adhesive layer 3 as in Comparative Example 1 and using the same urethane film 7 and polyurethane pressure-sensitive adhesive layer 8 as in Example 1 was used. Others were the same as in Example 1 and used as a catheter fixing patch with a window.
(Comparative Example 3)
A polyurethane nonwoven fabric having a thickness of 300 μm and a surface roughness of Comparative Example 1 of “26 μm” was pressed to a surface roughness of “5 μm”, a 30% tensile load of 3.78 N / 15 mm in the width direction and 4. in the longitudinal direction. It was set to 53N / 15mm. Other than that, a patch for fixing a catheter with a window was used in the same manner as in Comparative Example 1.

In order to compare the properties and practical properties of the examples and comparative examples, the following tests were conducted.
(1) Surface roughness of nonwoven fabric sheet (2) 30% tensile load of nonwoven fabric (width direction)
(3) 30% tensile load of the nonwoven fabric (longitudinal direction)
(4) Moisture permeability (g / m ² · 24 hr) of nonwoven fabric sheet (portion a in FIG. 2)
(5) Moisture permeability (g / m ² · 24 hr) of window sheet (portion b in FIG. 2)
(6) Moisture permeability (g / m ² · 24 hr) of the overlapping portion (portion c in FIG. 2) of the nonwoven fabric sheet and the window portion sheet
(7) Adhesive strength of nonwoven sheet and window sheet (N / 10mm)
(8) Dynamic friction coefficient of nonwoven fabric sheet (9) Dynamic friction coefficient of window sheet (10) Adhesive strength of nonwoven fabric sheet to YUPO paper (N / 15mm)
The measurement methods for (1) to (9) are as described above.

(10) The method for measuring the adhesive strength of the nonwoven fabric sheet to YUPO paper is a test piece of a patch prepared by cutting the YUPO paper into a length of 150 mm and a width of 15 mm in an atmosphere of 23 ° C. and 50% RH. Affixed and reciprocated once with a 2 kg rubber roll at a speed of 300 mm / min. After leaving in this state for 20 minutes, the peel force was measured under the conditions of a peel angle of 180 degrees and a peel speed of 300 mm / min, and the adhesive strength of the test piece to YUPO paper was determined.
The measurement was performed three times, and the average value was defined as the adhesive strength of the patch to YUPO paper (unit: N / 15 mm).
If the adhesive strength of the nonwoven fabric sheet is 1.0 to 3.0 (N / 15 mm), the adhesive strength required for fixing can be obtained.

(11) Practical characteristics As practical characteristics, the left and right patches of the examples and comparative examples are affixed to the inner side of the forearm of 9 adults and men, and “adhesiveness” and “slidability” after 24 hours. , “Peeling comfort” and “Peeling of window sheet” were tested. In order to evaluate all examples and comparative examples per person, the test was divided into three times.

1. The criteria for evaluation of “adhesion” are as follows.
○: The entire surface is attached. Δ: Floating is observed at the edge portion. X: Floating is observed at half or more of the surface.
2. The criteria for evaluating “slidability” are as follows.
The evaluation was based on the degree of sticking between the patch and the clothes.
○: Good slipperiness and no sticking of clothes on the patch.
Δ: The slipperiness is almost good, and the clothes slightly stick to the patch.
X: The slipperiness is poor and clothes stick to the patch.
3. The evaluation criteria for “sticking comfort” are as follows.
○: There is followability to the skin and the movement of the applied part is not controlled.
Δ: Less followability to the skin, and the movement of the applied site is slightly controlled.
×: There is no followability to the skin, and the movement of the applied site is controlled.
4). The evaluation criteria of “window sheet peeling” are as follows.
○: The window sheet is not peeled off from the nonwoven fabric sheet.
(Triangle | delta): The window part sheet | seat is partially peeled from the nonwoven fabric sheet.
X: Half or more of the window sheet is peeled off from the nonwoven fabric sheet.

(result)
Table 1 shows the values of the above characteristics, characteristic evaluation, and practical characteristics. The results of practical characteristics showed the highest evaluation criteria among 9 subjects. In addition, there was no thing with the same evaluation result ((circle), (triangle | delta), x).
In Comparative Example 3, the measurement result is not described in part of the characteristic evaluation because measurement was omitted because good results were not obtained in practical characteristics.

(Discussion)
The surface roughness of the nonwoven fabric sheets of Examples 1 to 3 is 11 μm to 13 μm, and those of Comparative Examples 1 and 2 are greatly different from 26 μm. The dynamic friction coefficient of the nonwoven fabric sheet is also about 3/4 lower in Examples 1 to 3 than in Comparative Examples 1 and 2.
It can be seen that the moisture permeability of the nonwoven fabric sheet is almost the same as in Examples 1 to 3, although it is slightly lower than Comparative Examples 1 and 2. The water vapor permeability of the window sheets of Examples 1 to 3 is improved by about 3.1 to 3.4 times that of the comparative example 1 using the acrylic adhesive. In addition, the moisture permeability of the overlapping portion of the nonwoven fabric sheet and the window sheet of Examples 1 to 3 is improved by about 1.3 to 1.6 times that of Comparative Example 1.

In the adhesives between the nonwoven fabric sheet and the window portion sheet, the surface roughness of the nonwoven fabric sheet in Examples 1 to 3 is smaller than that in Comparative Example 2 in which the same window portion sheet as in Examples 1 to 3 is used. Adhesiveness is improved by 0.5 to 2.2 times. The reason why almost the same adhesiveness as in Examples 1 to 3 is obtained in Comparative Example 1 is considered to be because an acrylic adhesive is used for the window sheet even if the surface roughness of the nonwoven fabric sheet is large. .

Furthermore, in practical characteristics considered to be important in actual use, Examples 1 to 3 show good results in all the evaluation items, indicating that they are practically effective. On the other hand, Comparative Examples 1 and 2 are inferior in slipperiness and are considered to be mainly due to the large roughness of the nonwoven fabric surface. In Comparative Example 2, peeling of the window portion sheet from the nonwoven fabric sheet is observed, and it is assumed that the adhesiveness between the window portion sheet and the nonwoven fabric sheet is low.

In Comparative Example 3, the nonwoven fabric was pressed from Comparative Example 1 to have a surface roughness of 5 μm, the moisture permeability of the nonwoven sheet was lowered, and the moisture permeability of the window sheet was also acrylic adhesive. It is significantly lower due to the use of the agent. In practical characteristics, the reason why the sticking feeling is slightly inferior is considered to be because the 30% tensile load of the nonwoven fabric is large. In addition, the slipperiness is poor, and the bumping is observed because the surface roughness of the nonwoven fabric is made too small, and the contact area with the garment etc. increases, making the slipperiness worse. It is guessed that it has been.

DESCRIPTION OF SYMBOLS 1 Patch fixing material for catheter with window 2 Nonwoven fabric 3 Adhesive layer 4 Nonwoven fabric sheet 5 Window portion 6 Window portion sheet 7 Urethane film 8 Polyurethane adhesive layer 10 Release paper

Claims (14)

It has a nonwoven fabric sheet provided with a pressure-sensitive adhesive layer on one surface of the nonwoven fabric, a window portion is formed on this nonwoven fabric sheet, a window portion sheet provided with a polyurethane pressure-sensitive adhesive layer is provided on one surface of the urethane film, A patch for fixing a catheter with a window, which is affixed to the other side of the nonwoven fabric so as to cover the window, and has a surface roughness of 7 to 20 μm on the other side of the nonwoven fabric to which the polyurethane adhesive layer is affixed. The windowed catheter fixing patch according to claim 1, wherein the surface of the nonwoven fabric on the other surface side has a coefficient of dynamic friction with respect to the cotton fabric of 0.1 to 1.0. 2. The windowed catheter fixing patch according to claim 1, wherein the urethane sheet surface of the window sheet has a coefficient of dynamic friction with respect to the cotton cloth of 0.1 to 0.8. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. The patch for fixing a catheter with a window according to claim 1, which is 8. The patch for fixing a catheter with a window according to claim 1, wherein the nonwoven fabric sheet has a moisture permeability of 5000 to 13000 g / m ² · 24 hr, and the window sheet has a moisture permeability of 2000 to 5000 g / m ² · 24 hr. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. The window nonwoven catheter fixing device according to claim 1, wherein the nonwoven fabric sheet has a water vapor transmission rate of 5000 to 13000 g / m ² · 24 hr, and the window sheet has a water vapor transmission rate of 2000 to 5000 g / m ² · 24 hr. Patch material. The patch for fixing a catheter with a window according to claim 1, wherein the adhesive force between the polyurethane pressure-sensitive adhesive layer of the window sheet and the other side of the nonwoven fabric sheet is 0.65 to 2.5 N / 10 mm. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. 8, the nonwoven fabric sheet has a moisture permeability of 5000 to 13000 g / m ² · 24 hr, the window sheet has a moisture permeability of 2000 to 5000 g / m ² · 24 hr, and the polyurethane pressure-sensitive adhesive layer of the window portion sheet and The patch for fixing a catheter with a window according to claim 1, wherein the adhesive strength of the nonwoven fabric sheet to the other surface side of the nonwoven fabric is 0.65 to 2.5 N / 10 mm. The patch for fixing a catheter with a window according to claim 1, wherein a 30% tensile load in the longitudinal direction and the width direction of the nonwoven fabric is 0.8 to 3.6 N / 15 mm. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. 8, the nonwoven fabric sheet has a moisture permeability of 5000 to 13000 g / m ² · 24 hr, the window sheet has a moisture permeability of 2000 to 5000 g / m ² · 24 hr, and the polyurethane pressure-sensitive adhesive layer of the window portion sheet and The adhesive strength of the nonwoven fabric sheet to the other side of the nonwoven fabric is 0.65 to 2.5 N / 10 mm, and the 30% tensile load in the longitudinal and width directions of the nonwoven fabric is 0.8 to 3.6 N / 15 mm. The patch for fixing a catheter with a window according to claim 1. The window-fixing patch for fixing a catheter according to claim 1, wherein the nonwoven fabric of the nonwoven fabric sheet is a polyurethane nonwoven fabric. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. is 8, a moisture permeability of 5000 ~ 13000g ^/ m 2 · 24hr of non-woven fabric sheet, a moisture permeability of 2000 ~ 5000g ^/ m 2 · 24hr window portions sheet, and a polyurethane adhesive layer of the window portion seat The adhesive strength of the nonwoven fabric sheet to the other side of the nonwoven fabric is 0.65 to 2.5 N / 10 mm, and the 30% tensile load in the longitudinal and width directions of the nonwoven fabric is 0.8 to 3.6 N / 15 mm. The patch for fixing a catheter with a window according to claim 1, wherein the nonwoven fabric of the nonwoven fabric sheet is a polyurethane nonwoven fabric. Further provided is a release paper covering the adhesive layer of the non-woven sheet of the patch and the polyurethane adhesive layer of the window sheet, the release paper being formed larger than the patch, The patch for fixing a catheter with a window according to claim 1, wherein the patch is divided into three sections on both sides. The surface of the nonwoven fabric on the other side of the nonwoven fabric has a dynamic friction coefficient of 0.1 to 1.0 with respect to the cotton cloth, and the urethane film surface of the window sheet has a dynamic friction coefficient of 0.1 to 0.00 with respect to the cotton cloth. is 8, a moisture permeability of 5000 ~ 13000g ^/ m 2 · 24hr of non-woven fabric sheet, a moisture permeability of 2000 ~ 5000g ^/ m 2 · 24hr window portions sheet, and a polyurethane adhesive layer of the window portion seat The adhesive strength of the nonwoven fabric sheet to the other side of the nonwoven fabric is 0.65 to 2.5 N / 10 mm, and the 30% tensile load in the longitudinal and width directions of the nonwoven fabric is 0.8 to 3.6 N / 15 mm. The nonwoven fabric of the nonwoven fabric sheet is a polyurethane nonwoven fabric, and a release paper is further provided to cover the adhesive layer of the nonwoven fabric sheet and the polyurethane adhesive layer of the window sheet, and the release paper is made of the adhesive material. Is large is formed and, windowed catheter locking patch of claim 1, which is divided into three wards band covering the window portion and the district bands on both sides.

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