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WO2014045346A1 - Dispositif de mesure de composant - Google Patents

Dispositif de mesure de composant Download PDF

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Publication number
WO2014045346A1
WO2014045346A1 PCT/JP2012/073890 JP2012073890W WO2014045346A1 WO 2014045346 A1 WO2014045346 A1 WO 2014045346A1 JP 2012073890 W JP2012073890 W JP 2012073890W WO 2014045346 A1 WO2014045346 A1 WO 2014045346A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
measurement
light emitting
chip
emitting element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2012/073890
Other languages
English (en)
Japanese (ja)
Inventor
矢口喜明
佐藤浩明
長澤靖
池田朋弘
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Priority to PCT/JP2012/073890 priority Critical patent/WO2014045346A1/fr
Publication of WO2014045346A1 publication Critical patent/WO2014045346A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held

Definitions

  • the present invention relates to a component measuring apparatus for measuring a predetermined component of a body fluid collected on a measuring chip.
  • component measuring devices that detect biological components in body fluids such as blood and urine and measure the amount and properties of the components are widely used.
  • a disposable measuring chip is mounted on the chip mounting portion constituting the component measuring apparatus, and blood is soaked into the test paper of the measuring chip. Then, the blood glucose level of the blood soaked into the test paper is measured (see, for example, JP-A-2011-64596).
  • the component measuring apparatus is moved from the standby mode in which the power consumption (average power consumption per unit time) of the component measuring apparatus is low by turning on the power button of the component measuring apparatus. After switching to the measurement mode in which the power source is turned on, it is necessary to perform an operation of mounting the measuring chip on the chip mounting portion. Therefore, especially for a diabetic patient who needs to measure a blood glucose level several times a day (for example, four times), these operations are likely to be a burden.
  • the measurement chip may be mounted on the chip mounting portion without turning on the power button, and blood may be spotted on the measurement chip.
  • the measurement chip is replaced with a new one. Since it must be replaced with a new one, the cost for measuring the blood sugar level increases, and it becomes a burden on the user and the like.
  • the present invention has been made in consideration of such a problem, and can automatically switch from the standby mode to the measurement mode when the measurement chip is mounted on the chip mounting portion. It is an object of the present invention to provide a component measuring apparatus that can simplify the configuration and reduce the burden on the user or the like.
  • a component measuring apparatus is a component measuring apparatus for measuring a predetermined component of a body fluid collected on a measuring chip, and includes a chip mounting unit on which the measuring chip is mounted, and the chip mounting unit A light emitting element for irradiating light to the measuring chip mounted on the light emitting element, a light receiving element for detecting reflected light of the light irradiated from the light emitting element to the measuring chip, and light emission for causing the light emitting element to emit light A control unit, a chip mounting determination unit that determines whether or not the measurement chip is mounted on the chip mounting unit based on the reflected light detected by the light receiving element, and a power supply of the component measuring device is turned on A mode switching control unit that switches between a measurement mode that is in a state and a standby mode that consumes less power than the measurement mode, and the light emission control unit causes the light emitting element to emit light during the standby mode.
  • the mode switching control unit that switches between a measurement mode that is in a state and a standby mode that consumes
  • the mode switching control unit switches from the standby mode to the measurement mode.
  • the standby mode can be automatically switched to the measurement mode.
  • the component measuring device is provided with a power button
  • the standby mode is automatically switched to the measuring mode, so the operation of the power button is omitted. Can do.
  • the operation of the component measuring apparatus is simplified, and an operation error (forgetting to press the power button) by the user or the like can be prevented, so that the burden on the user or the like can be reduced.
  • the light emission control unit emits the light emitting element so that the light emission intensity of the light emitting element during the standby mode is smaller than the light emission intensity of the light emitting element during the measurement mode. You may let them.
  • the light emission intensity of the light emitting element in the standby mode is smaller than the light emission intensity of the light emitting element in the measurement mode, power consumption in the standby mode can be suitably suppressed.
  • the light emitting element a first light emitting element that emits light having a first wavelength and a second light that emits light having a second wavelength different from the first wavelength are used.
  • a light emitting element may be used, and the light emission control unit may cause the first light emitting element or the second light emitting element to emit light during the standby mode.
  • the first light emitting element and the second light emitting element are used as the light emitting elements, it is possible to irradiate the measurement chip with two types of light having different wavelengths. Thereby, the measurement of the predetermined component of a bodily fluid can be performed with high precision. Further, since the first light emitting element or the second light emitting element emits light during the standby mode, power consumption during the standby mode can be efficiently suppressed.
  • the light emission control unit may cause the light emitting element to emit light intermittently during the standby mode.
  • the light emitting element since the light emitting element emits light intermittently during the standby mode, power consumption can be reduced as compared with the case where the light emitting element emits light continuously.
  • the light emission control unit causes the light emitting element to emit light intermittently during the measurement mode, and the light emission interval of the light emitting element during the standby mode corresponds to the light emission interval during the measurement mode.
  • the light emitting element may emit light so as to be longer than the light emission interval of the light emitting element.
  • the light emission interval of the light emitting element in the standby mode is longer than the light emission interval of the light emitting element in the measurement mode, for example, the light emission interval of the light emitting element in the standby mode and the light emission in the measurement mode Compared with the case where the light emission intervals of the elements are the same, power consumption during the standby mode can be suppressed.
  • the mode switching control unit may switch from the measurement mode to the standby mode after a predetermined time has elapsed since the predetermined component of the body fluid was measured.
  • the mode switching control unit automatically switches from the measurement mode to the standby mode after a predetermined time has elapsed after the measurement of the predetermined component of the body fluid, it is wasteful while further reducing the burden on the user and the like. Power consumption can be reduced.
  • an availability determination unit that determines whether the measurement chip is usable based on the reflected light detected by the light receiving element during the measurement mode. Further, the mode switching control unit may switch from the measurement mode to the standby mode when the usability determination unit determines that the measurement chip is unusable.
  • the mode switching control unit since the mode switching control unit switches from the measurement mode to the standby mode when the availability determination unit determines that the measurement chip is unusable, the measurement chip is switched to the chip mounting unit. It is possible to reduce power consumption until it is mounted again.
  • the body fluid is collected in the measuring chip in a state where a predetermined component of the body fluid can be measured based on the reflected light detected by the light receiving element during the measurement mode.
  • a body fluid collection determination unit that determines whether the body fluid has been collected, and the mode switching control unit is configured to determine that the body fluid is not collected on the measurement chip in a state in which a predetermined component of the body fluid can be measured.
  • the measurement mode may be switched to the standby mode.
  • the mode switching control unit determines from the measurement mode that the body fluid collection determination unit determines that the body fluid is not collected in the measurement chip in a state where the predetermined component of the body fluid can be measured. Since the mode is switched to the standby mode, it is possible to suppress power consumption until the measurement chip is mounted on the chip mounting unit again.
  • FIG. 2 is a partially omitted enlarged cross-sectional view of the tip side of the component measuring apparatus shown in FIG. 1. It is a block diagram for demonstrating the control part which comprises the said component measuring apparatus. It is the flowchart which showed the procedure which measures a blood glucose level using the said component measuring apparatus.
  • the component measuring apparatus 10 is a blood glucose meter that can be mounted with a measuring chip 200 at its tip and measures and displays the glucose concentration (blood glucose level) in the blood collected on the measuring chip 200. It is configured. First, the measurement chip 200 will be described.
  • the measuring chip 200 is a so-called disposable product and is packaged in an individual package. As shown in FIGS. 2 and 5, the measuring chip 200 includes a chip main body 202 integrally formed of resin or the like, and a test paper 204 provided on the chip main body 202.
  • the chip body 202 includes a plurality of (four in this embodiment) mounting claws 206 formed on the base end side, a disk-shaped base portion 208 provided on the distal end side of the mounting claws 206, and a base portion 208. And a suction projection 210 protruding from the approximate center toward the tip side.
  • the plurality of mounting claws 206 are arranged at equal intervals in the circumferential direction on the outer peripheral portion of the base portion 208.
  • the chip body 202 is formed with a small-diameter blood introduction path 212 that opens to the proximal end surface of the base portion 208 and the distal end surface of the suction protrusion 210.
  • the test paper 204 is made of, for example, polyethersulfone and is fixed to the base end surface of the base portion 208.
  • the reagent impregnated in the test paper 204 include color formers such as glucose oxidase (GOD), peroxidase (POD), 4-aminoantipyrine, and N-ethyl N- (2-hydroxy-3-sulfopropyl). It is done.
  • the component measuring apparatus 10 will be described.
  • the side on which the measurement chip 200 is attached is referred to as “front end side”, and the opposite side is referred to as “base end side”.
  • the component measuring apparatus 10 includes an elongated casing 12, a main control board 14 disposed in the casing 12, and a liquid crystal provided on the main control board 14.
  • the display 16 the ejector 18 disposed in the housing 12, the chip mounting portion 20 that is disposed in the opening on the front end side of the housing 12 and the measuring chip 200 is mounted, and the chip mounting portion 20.
  • a photometric unit 22 arranged.
  • the casing 12 is formed in a rectangular parallelepiped shape whose base end portion and intermediate portion can be easily gripped by a user with one hand, and the tip end portion is formed narrow. Has been.
  • the housing 12 is made of resin or the like, and includes a first case 24 formed in a U-shaped cross section and a second case 26 fixed to the first case 24.
  • the first case 24 includes a battery housing portion 30 that houses a plurality of (two in this embodiment) batteries 28 and a battery lid 32 that is detachably provided on the battery housing portion 30.
  • a button-type battery is used as the battery 28, but it is needless to say that a round dry battery, a square dry battery, or a secondary battery may be used as the battery 28.
  • each of the pair of operation buttons 34 is disposed are arranged side by side along the width direction of the second case 26.
  • the display screen of the liquid crystal display 16 can be operated by a user or the like operating each operation button 34.
  • each operation button 34 does not function as a power button. That is, in this embodiment, the component measuring apparatus 10 does not include a power button.
  • An opening window 38 in which the liquid crystal display 16 is disposed is formed substantially at the center of the second case 26.
  • a liquid crystal cover 40 is attached to the opening window 38 so as to cover the liquid crystal display 16.
  • a protective panel 42 that covers the pair of operation buttons 34 and the liquid crystal cover 40 is attached to the second case 26.
  • a long hole 48 into which the leg 46 of the ejector operation unit 44 is slidably inserted is formed at the tip of the second case 26.
  • the ejector operation unit 44 is connected to the ejector 18 and is formed in a shape that is easy for a user or the like to operate with fingers.
  • the long hole 48 extends along the longitudinal direction of the housing 12, and the ejector operation unit 44 and the ejector 18 can slide with respect to the housing 12 along the longitudinal direction.
  • the main control board 14 is fixed to the second case 26 by a plurality of screw members 50 (see FIG. 3).
  • a predetermined wiring circuit is formed on the main control board 14 by printing.
  • the ejector 18 is integrally formed of resin or the like, and is in contact with the measuring chip 200 connected to the fixing portion 52 provided in the ejector operation portion 44 and the distal end side of the fixing portion 52.
  • the fixing portion 52 is a plate member extending along the longitudinal direction of the housing 12, and a screw member 56 for fixing the ejector 18 to the ejector operation portion 44 on the base end side (see FIG. 3).
  • a plurality of (two in the present embodiment) insertion holes 58 through which are inserted are arranged along the width direction of the fixed portion 52.
  • the notch 60 is provided with a coil spring (spring member, biasing member, elastic member) 62 for biasing the ejector 18 toward the proximal end with respect to the chip mounting portion 20.
  • a protrusion 66 is formed on the spring support wall 64 that constitutes.
  • the extruding part 54 has a shape such that a part of the cylindrical body is cut out along the axial direction.
  • the distal end surface of the pushing portion 54 faces the proximal end surfaces of the plurality of mounting claws 206 that constitute the measuring chip 200.
  • the chip mounting portion 20 is integrally formed of resin or the like, and has a rectangular cylindrical base 68 disposed in the opening on the distal end side of the housing 12, and a cylindrical portion 70 that continues to the distal end side of the base 68.
  • the width dimension of the base portion 68 is smaller than the outer diameter of the cylindrical portion 70.
  • a protrusion 72 (see FIG. 5) is formed in a portion of the base portion 68 that faces the protrusion 66 of the ejector 18 so that the distal end side of the coil spring 62 is fitted.
  • an annular locking portion 74 that locks the plurality of mounting claws 206 of the measuring chip 200 is formed.
  • the photometry unit 22 protrudes toward the front end side from the sub-control board 76 electrically connected to the main control board 14, a plate-like board arrangement part 78 provided with the sub-control board 76, and the board arrangement part 78. And a cylindrical light guide 80.
  • the sub-control board 76 has a plurality of (two in this embodiment) insertion holes 84 through which screw members 82 for fixing the sub-control board 76 to the board placement portion 78 are inserted.
  • the sub-control board 76 irradiates the test paper 204 with the first light emitting element 85 that irradiates the test paper 204 with light having the first wavelength and the light having the second wavelength different from the first wavelength.
  • a second light emitting element 86 for detecting the reflected light guided from the test paper 204 and a light receiving element 88 for detecting (receiving) the light are mounted.
  • a light emitting diode (LED) is used as the first light emitting element 85 and the second light emitting element 86, and a photodiode (PD) is used as the light receiving element 88. Further, a through hole 90 is formed between the first light emitting element 85 and the second light emitting element 86 and the light receiving element 88 in the sub-control board 76.
  • LED light emitting diode
  • PD photodiode
  • the substrate placement portion 78 and the light guide portion 80 are integrally formed of resin or the like.
  • a plurality of (two in this embodiment) insertion holes 94 are formed in the substrate placement portion 78 through which screw members 92 for fixing the photometry portion 22 to the chip mounting portion 20 are inserted.
  • the light guide unit 80 is located inside the extrusion unit 54 of the ejector 18. That is, the push-out portion 54 of the ejector 18 is disposed between the chip mounting portion 20 and the light guide portion 80. Thereby, the component measuring apparatus 10 can be comprised compactly.
  • the light guide portion 80 is formed with a partition wall 100 that extends along the axial direction and partitions the light guide portion 80 into an irradiation light path 96 and a reflection light path 98.
  • a base end portion of the partition wall 100 is located in the through hole 90 of the sub control board 76.
  • the lens 102 is inserted and held in the front end side opening of the light guide 80.
  • the lens 102 includes an irradiation lens 104 that condenses the light guided from the irradiation light path 96 onto the test paper 204, and a light guide lens 106 that condenses the reflected light guided from the test paper 204 onto the light receiving element 88. Yes.
  • An O-ring 108 is interposed between the lens 102 and the light guide unit 80.
  • the component measurement apparatus 10 further includes a power supply unit 110, a storage unit 112, and a control unit 114.
  • the power supply unit 110 supplies the power of each battery 28 to the control unit 114.
  • the storage unit 112 is configured as a ROM or RAM that stores a predetermined program.
  • the control unit 114 is configured as a microcomputer that is mounted on the main control board 14 and performs predetermined processing.
  • control unit 114 is provided with a mode switching control unit 116, a light emission control unit 118, a chip attachment determination unit 120, a usability determination unit 122, and a blood collection determination unit (body fluid collection determination unit) 124.
  • the mode switching control unit 116 switches between the measurement mode and the standby mode (non-measurement mode) by controlling the power supply unit 110.
  • the measurement mode is a state in which the power source of the component measuring apparatus 10 is turned on and the blood glucose level of the blood collected on the test paper 204 can be measured based on the reflected light detected by the light receiving element 88.
  • the standby mode is a state in which the power consumption (average power consumption per unit time) is lower than that in the measurement mode, and the blood glucose level of the blood cannot be measured.
  • the liquid crystal display 16 in the measurement mode, the liquid crystal display 16 is turned on, and in the standby mode, the liquid crystal display 16 is turned off and the photometry unit 22, the mode switching control unit 116, and the light emission control unit 118 can be driven.
  • the light emission control unit 118 causes the first light emitting element 85 and the second light emitting element 86 to emit light.
  • the chip mounting determination unit 120 determines whether or not the measurement chip 200 is mounted on the chip mounting unit 20 based on the reflected light detected by the light receiving element 88.
  • the configuration in which the measurement chip 200 is not mounted includes a configuration in which the measurement chip 200 is mounted incompletely on the chip mounting portion 20 (for example, a part of the mounting nail of the measurement chip 200) Only 206 is locked to the annular locking portion 74 of the chip mounting portion 20 and the other mounting claw 206 is not locked to the annular locking portion 74.
  • the usability determination unit 122 determines whether or not the measurement chip 200 is usable based on the reflected light detected by the light receiving element 88 during the measurement mode.
  • the blood collection determination unit 124 determines whether blood is collected on the test paper 204 in a measurable state based on the reflected light detected by the light receiving element 88 during the measurement mode.
  • the component measuring apparatus 10 is basically configured as described above, and blood glucose measurement using the component measuring apparatus 10 will be described next.
  • the component measuring apparatus 10 is in a standby mode (see step S1 in FIG. 7).
  • the light emission control unit 118 causes the first light emitting element 85 to emit light in pulses (step S2).
  • the light emission control unit 118 intermittently emits light only from the first light emitting element 85.
  • the light emission control unit 118 causes the first light emitting element 85 to emit light in pulses so that the light emission interval of the first light emitting element 85 in the standby mode is longer than the light emission interval of the first light emitting element 85 in the measurement mode.
  • the power consumption in the standby mode is suppressed. Can do.
  • the light emission control unit 118 uses the light emission intensity of the first light emitting element 85 in the measurement mode (the light emission intensity of the first light emitting element 85 in step S2).
  • the first light emitting element 85 is caused to emit light so as to be smaller than the light emission intensity of the first light emitting element 85 in steps S5, S9, and S10 described later. Thereby, power consumption during the standby mode can be suitably suppressed.
  • the light emitted from the first light emitting element 85 passes through the irradiation light path 96 and enters the irradiation lens 104 and is guided to the tip opening of the chip mounting portion 20.
  • the measurement chip 200 is completely mounted on the chip mounting unit 20
  • the light emitted from the first light emitting element 85 is condensed and irradiated onto the test paper 204 and reflected by the test paper 204.
  • the light enters the light guide lens 106 as reflected light, passes through the reflected light path 98, and is condensed and irradiated to the light receiving element 88.
  • the measurement chip 200 is not mounted on the chip mounting unit 20, the light emitted from the first light emitting element 85 is not detected by the light receiving element 88.
  • the chip mounting determination unit 120 determines whether or not the measurement chip 200 is mounted on the chip mounting unit 20 based on the reflected light detected by the light receiving element 88 (step S3).
  • the chip mounting determination unit 120 mounts the measurement chip 200 on the chip mounting unit 20 when the amount of reflected light (the amount of reflected light) detected by the light receiving element 88 exceeds a predetermined threshold. It is determined that the measurement chip 200 is not mounted on the chip mounting portion 20 when the amount of reflected light is equal to or less than the threshold value.
  • the measurement chip 200 is mounted on the chip mounting portion 20.
  • the light emitted from the first light emitting element 85 in a state where the measurement chip 200 is not mounted on the chip mounting unit 20 passes through the tip opening of the chip mounting unit 20 and is on the outside of the component measuring apparatus 10.
  • reflected light may be detected by the light receiving element 88. Since the amount of reflected light detected in this way is equal to or less than the threshold value, it is possible to eliminate the concern that the measurement chip 200 is erroneously determined to be mounted on the chip mounting portion 20 in these cases.
  • step S3 NO
  • the process of step S3 is repeated.
  • step S3 when the chip mounting determination unit 120 determines that the measurement chip 200 is mounted on the chip mounting unit 20 (step S3: YES), the mode switching control unit 116 switches from the standby mode to the measurement mode (Ste S4). Thereby, the component measuring apparatus 10 will be in the state which can measure a blood glucose level, when the liquid crystal display 16 lights.
  • the usability determination unit 122 determines whether or not the measurement chip 200 mounted on the chip mounting unit 20 is usable (step S5). Specifically, for example, the light emission control unit 118 causes the first light emitting element 85 and the second light emitting element 86 to alternately emit pulses, and the usability determination unit 122 uses the reflected light amount detected by the light receiving element 88 as a test paper. It is determined whether or not blood or the like is attached to 204 (whether or not it is an unused measuring chip 200). Note that after the determination by the usability determination unit 122 is completed, the light emission control unit 118 stops the pulse light emission of the first light emitting element 85 and the second light emitting element 86.
  • step S5 NO
  • the control unit 114 displays NG on the liquid crystal display 16 (for example, “measurement chip NG”). Is displayed).
  • step S7 the mode switching control unit 116 performs the process of step S3 described above. This is because it is necessary to mount the measurement chip 200 on the chip mounting unit 20 again.
  • step S5 determines that the measurement chip 200 is usable
  • the user or the like collects blood of the measurement subject (user or the like). (Step S8).
  • control unit 114 may display “measurement chip OK” on the liquid crystal display 16, for example.
  • the user or the like can grasp that the measurement chip 200 can be used by looking at the display on the liquid crystal display 16, and thus blood can be collected immediately.
  • a finger is punctured with a dedicated puncture device (not shown), and a small amount of blood (eg, about 0.3 to 1.5 ⁇ L) is allowed to flow out onto the skin. Then, the tip of the suction protrusion 210 of the measuring chip 200 is brought into contact with (spotted on) the blood that has flowed out of the fingertip.
  • a dedicated puncture device not shown
  • a small amount of blood eg, about 0.3 to 1.5 ⁇ L
  • blood is taken into the blood introduction path 212 of the measuring chip 200 and sucked to the proximal end by capillary action.
  • the sucked blood soaks into the test paper 204 and diffuses (deploys) outward in the radial direction of the test paper 204.
  • the glucose in the blood and the coloring reagent contained in the test paper 204 start to react, and the test paper 204 is colored according to the amount of glucose.
  • the blood collection determination unit 124 determines whether blood has been collected in the measurement chip 200 in a state where the blood glucose level can be measured (step S9). That is, the blood collection determination unit 124 determines whether or not the amount of blood spotting and blood deployment are good (appropriate) based on the reflected light detected by the light receiving element 88.
  • the light emission control unit 118 causes the first light emitting element 85 and the second light emitting element 86 to alternately emit pulses, and the blood collection determination unit 124 determines the amount of blood spotted based on the amount of reflected light detected by the light receiving element 88. And determining whether blood deployment is good. Note that after the determination by the blood collection determination unit 124 is completed, the light emission control unit 118 stops the pulse light emission of the first light emitting element 85 and the second light emitting element 86.
  • step S9 NO
  • the control unit 114 displays NG on the liquid crystal display 16 (for example, (Displayed as “blood spot NG” or “blood spread NG”) (step S6). Then, after switching from the measurement mode to the standby mode (step S7), the mode switching control unit 116 performs the process of step S3 described above.
  • the component measurement apparatus 10 measures the measurement chip 200.
  • the blood glucose level in the collected blood is measured (step S10).
  • the light emission control unit 118 causes the first light emitting element 85 and the second light emitting element 86 to alternately emit light
  • the control unit 114 measures the color intensity of the test paper 204 based on the amount of reflected light detected by the light receiving element 88. To do. Time measurement is started from the time when blood soaks into the test paper 204 and the amount of reflected light changes greatly, and the blood sugar level is calculated based on the amount of reflected light after a predetermined time has elapsed.
  • the color produced by the reaction between the coloring reagent and glucose is detected by the light emitted from the first light emitting element 85, and the color density according to the amount of glucose is measured. Further, red blood cells are detected by light emitted from the second light emitting element 86, and the red density of the red blood cells is measured. Then, the glucose value obtained from the color concentration is corrected using the hematocrit value obtained from the red concentration, and the blood glucose level is obtained.
  • control unit 114 displays the measured blood glucose level on the liquid crystal display 16 (step S11). Thereafter, the user or the like removes the measuring chip 200 from the chip mounting part 20 by sliding the ejector operation part 44 to the tip side (step S12).
  • the mode switching control unit 116 switches from the measurement mode to the standby mode (step S13). As a result, the liquid crystal display 16 is turned off. At this stage, the current flowchart ends.
  • the test of the measuring chip 200 from the first light emitting element 85 is performed when the measuring chip 200 is mounted on the chip mounting portion 20.
  • the reflected light of the light irradiated on the paper 204 is detected by the light receiving element 88.
  • the mode switching control unit 116 switches from the standby mode. Since the measurement mode is switched, the standby mode can be automatically switched to the measurement mode when the measurement chip 200 is mounted on the chip mounting unit 20. Thereby, it is not necessary to provide a power button on the component measuring apparatus 10. Therefore, the configuration of the component measuring apparatus 10 can be simplified.
  • the component measuring apparatus 10 is provided with a power button, when the measurement chip 200 is mounted on the chip mounting unit 20, the standby mode is automatically switched to the measurement mode. Can be omitted. Thereby, the operation of the component measuring apparatus 10 is simplified, and an operation error (forgetting to press the power button) by the user or the like can be prevented, so that the burden on the user or the like can be reduced.
  • the first light emitting element 85 having the first wavelength and the second light emitting element 86 having the second wavelength different from the first wavelength are provided.
  • the blood glucose level can be measured with high accuracy using light. Further, the determination by the usability determination unit 122 and the blood collection determination unit 124 can be performed with high accuracy.
  • the first light emitting element 85 since the first light emitting element 85 emits light intermittently during the standby mode, power consumption can be reduced compared to the case where the first light emitting element 85 emits light continuously. it can.
  • the light emission control unit 118 emits light from the first light emitting element 85 when the light emission interval of the first light emitting element 85 in the standby mode (the light emission interval of the first light emitting element 85 in step S2) is in the measurement mode.
  • the first light emitting element 85 emits light so as to be longer than the interval (the light emitting interval of the first light emitting element 85 in each of steps S5, S9, and S10).
  • the power consumption in the standby mode is suppressed. Can do.
  • the mode switching control unit 116 automatically switches from the measurement mode to the standby mode after a predetermined time elapses after the blood glucose level measurement is completed. Electric power can be reduced.
  • the mode switching control unit 116 switches from the measurement mode to the standby mode when the usability determining unit 122 determines that the measuring chip 200 is unusable, so that the measuring chip 200 is changed to the chip mounting unit 20. It is possible to reduce the power consumption until it is mounted again.
  • the mode switching control unit 116 determines that the blood spotting amount or blood deployment of the measurement chip 200 is not good (no blood is collected in the measurement chip 200 in a state where the blood sugar level can be measured), and the blood collection determination unit When the determination is made at 124, the measurement mode is switched to the standby mode, so that power consumption until the measurement chip 200 is mounted on the chip mounting unit 20 again can be suppressed.
  • the light emission control unit 118 may cause only the second light emitting element 86 to emit light during the standby mode. Even in this case, power consumption during the standby mode can be suitably suppressed.
  • the component measuring apparatus may be any device that measures a predetermined component of a body fluid, and is not limited to a blood glucose meter that measures a blood glucose level.

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  • Health & Medical Sciences (AREA)
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  • Physics & Mathematics (AREA)
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  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
PCT/JP2012/073890 2012-09-19 2012-09-19 Dispositif de mesure de composant Ceased WO2014045346A1 (fr)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018123676A1 (fr) * 2016-12-27 2018-07-05 アルプス電気株式会社 Module capteur et système d'affichage d'informations biométriques
JP2019042004A (ja) * 2017-08-31 2019-03-22 富士ゼロックス株式会社 光学測定装置及び光学測定プログラム
WO2021166471A1 (fr) * 2020-02-20 2021-08-26 テルモ株式会社 Dispositif de mesure de composant, ensemble de dispositifs de mesure de composant et procédé de traitement d'informations
JPWO2021166510A1 (fr) * 2020-02-20 2021-08-26

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008120614A1 (fr) * 2007-03-30 2008-10-09 Terumo Kabushiki Kaisha Appareil de mesure d'ingrédients de liquide organique
JP2010217074A (ja) * 2009-03-18 2010-09-30 Panasonic Corp 免疫定量測定システム
JP2011064596A (ja) * 2009-09-17 2011-03-31 Terumo Corp 血糖計

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008120614A1 (fr) * 2007-03-30 2008-10-09 Terumo Kabushiki Kaisha Appareil de mesure d'ingrédients de liquide organique
JP2010217074A (ja) * 2009-03-18 2010-09-30 Panasonic Corp 免疫定量測定システム
JP2011064596A (ja) * 2009-09-17 2011-03-31 Terumo Corp 血糖計

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018123676A1 (fr) * 2016-12-27 2018-07-05 アルプス電気株式会社 Module capteur et système d'affichage d'informations biométriques
JPWO2018123676A1 (ja) * 2016-12-27 2019-07-11 アルプスアルパイン株式会社 センサモジュールおよび生体関連情報表示システム
US11096592B2 (en) 2016-12-27 2021-08-24 Alps Alpine Co., Ltd. Sensor module and biological information display system
JP2019042004A (ja) * 2017-08-31 2019-03-22 富士ゼロックス株式会社 光学測定装置及び光学測定プログラム
US11534088B2 (en) 2017-08-31 2022-12-27 Fujifilm Business Innovation Corp. Optical measuring apparatus and non-transitory computer readable medium
JP7024261B2 (ja) 2017-08-31 2022-02-24 富士フイルムビジネスイノベーション株式会社 光学測定装置及び光学測定プログラム
WO2021166510A1 (fr) * 2020-02-20 2021-08-26 テルモ株式会社 Dispositif de mesure de composant, ensemble de dispositif de mesure de composant et procédé de traitement d'informations
JPWO2021166471A1 (fr) * 2020-02-20 2021-08-26
JPWO2021166510A1 (fr) * 2020-02-20 2021-08-26
CN114729923A (zh) * 2020-02-20 2022-07-08 泰尔茂株式会社 成分测定装置、成分测定装置组以及信息处理方法
CN114729897A (zh) * 2020-02-20 2022-07-08 泰尔茂株式会社 成分测定装置、成分测定装置组以及信息处理方法
WO2021166471A1 (fr) * 2020-02-20 2021-08-26 テルモ株式会社 Dispositif de mesure de composant, ensemble de dispositifs de mesure de composant et procédé de traitement d'informations
US12188875B2 (en) 2020-02-20 2025-01-07 Terumo Kabushiki Kaisha Component measurement apparatus, component measurement apparatus set, and information processing method
JP7617893B2 (ja) 2020-02-20 2025-01-20 テルモ株式会社 成分測定装置、成分測定装置セット及び情報処理方法
JP7617894B2 (ja) 2020-02-20 2025-01-20 テルモ株式会社 成分測定装置、成分測定装置セット及び情報処理方法

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