Classifications

• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
  • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
  • A23L33/17—Amino acids, peptides or proteins
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
  • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
  • A23L33/15—Vitamins
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
  • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
  • A23L33/16—Inorganic salts, minerals or trace elements
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P3/00—Drugs for disorders of the metabolism
  • A61P3/02—Nutrients, e.g. vitamins, minerals
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
  • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

• the present invention relates to a semi-solidified nutrient.
• the above-mentioned semi-solidified nutrients in the medical field are mainly applied to sick people, infants, elderly people, etc., and the administration method is roughly divided into oral administration and tube administration.
• Oral administration is mainly applied to those who have difficulty swallowing with difficulty in mastication and swallowing due to aging or cerebrovascular disorders. People who have difficulty swallowing have difficulty eating a normal meal. In particular, when ingesting water, low-viscosity juice, or the like, the ability to swallow is reduced, and therefore sufficient consideration must be given to backflow and dusk.
• hospitals have devised methods such as mixing commercially available thickeners with liquid nutrients, tea, water, etc., and giving them after giving appropriate viscosity.
• the pharyngeal residue may occur due to partial lumps, and the viscosity increases after the thickener is added to the food (stable viscosity). There is a problem that preparation takes time because it takes a little time to prepare.
• Tube administration is mainly applied to elderly people and patients who cannot be administered orally, and semi-solid nutrients are administered using enteral nutrition.
• enteral nutrition is a nutritional method aimed at meeting the demand for calories and nutrients (protein sources, minerals, vitamins, etc.) required by the living body, and is the physiological method following oral intake. Is. For this reason, enteral nutrition is usually selected over high calorie infusion therapy (TPN), which is intravenous nutritional supplementation, for patients with intestinal function that cannot be ingested.
• TPN high calorie infusion therapy
• examples of the administration method of the nutrient include administration using an oral gastric tube, administration using a nasogastric tube, administration using a gastrostoma, and the like. When used, administration using gastrostomy is primarily selected.
• the required properties include moderate viscosity, and it is difficult for the nutrients to remain in the tube when it is administered from the gastrostomy through the tube, and it is difficult to contaminate the tube.
• viscosity it is important to maintain a high viscosity.
• the above-mentioned semi-solidified nutrient in the food field has a unique texture and can easily and quickly ingest nutrients, so it is mainly applied to portable foods, diet foods and the like.
• the above-mentioned semi-solidified nutrient in the food field has a unique texture and can easily and quickly ingest nutrients, so it is mainly applied to portable foods, diet foods and the like.
• Some are sold as nutritional functional foods that further contain nutritional components.
• Patent Document 1 discloses a semi-solid nutrient obtained by adding agar or whole egg as a semi-solid agent to the enteral nutrient as a semi-solid nutrient applied to the enteral nutrition method.
• Patent Document 2 discloses a gel enteral nutrient comprising agar and alginic acid and / or a salt thereof.
• the semi-solidified nutrient prepared by using alginic acid together with agar has a non-uniform semi-solidified nutrient because sodium alginate itself reacts with calcium ions to form aggregates. It is easy to become an agent.
• an object of the present invention is to provide a semi-solidified nutrient in which the occurrence of water separation is suppressed.
• the present inventors have found that the above-mentioned problems can be solved by adding a predetermined amount of agar and a predetermined amount of thickener to the semi-solidified nutrient, and the present invention has been completed. I came to let you.
• the present invention includes a nutrient containing a carbohydrate and protein source, water, agar, at least one thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum,
• a semi-solidified nutrient containing at least the agar content is 0.1 to 0.8% by mass relative to the total nutrient amount, and the thickener content is relative to the total nutrient amount It is a semi-solidified nutrient that is 0.2 to 1.0% by mass.
• the present invention provides a semi-solidified nutrient in which the occurrence of water separation is suppressed.
• the semi-solidified nutrient according to the present invention is at least one selected from the group consisting of nutrients including carbohydrates and protein sources, moisture, agar, pectin, locust bean gum, soybean polysaccharide, and guar gum.
• Nutrients essentially include carbohydrate and protein sources.
• the nutrient may further contain at least one selected from the group consisting of lipids, vitamins, minerals, and dietary fiber as an optional component.
• the total amount of nutrients in the semi-solidified nutrient is preferably 10 to 50% by mass, and more preferably 20 to 35% by mass.
• Carbohydrates are also called carbohydrates and serve as energy sources.
• the carbohydrate that can be used is not particularly limited as long as it is absorbed into a living body and becomes an energy source, and examples thereof include monosaccharides, disaccharides, and polysaccharides.
• monosaccharides include glucose (glucose), fructose (fructose), galactose and the like.
• disaccharide include sucrose (sucrose), lactose (lactose), maltose (malt sugar), isomaltose, trehalose and the like.
• Specific examples of the polysaccharide include starch (amylose, amylopectin), dextrin and the like. Of these, dextrin is preferably used.
• Dextrin is a general term for substances in which several ⁇ -glucoses are polymerized by glycosidic bonds, and can be obtained by hydrolysis of starch. Since dextrin has a slow degradation rate in the small intestine and is slowly absorbed, it can prevent a rapid increase in blood sugar. Moreover, by using dextrin, the osmotic pressure of the semi-solidified nutrient can be reduced, and osmotic diarrhea can be prevented.
• the dextrin either a high molecular dextrin having a high degree of polymerization of ⁇ -glucose or a low molecular dextrin having a low degree of polymerization of ⁇ -glucose may be used, but a high molecular dextrin capable of further reducing the osmotic pressure should be used. Is preferred.
• the low molecular dextrin is also called maltodextrin and is usually a polymer of 3 to 5 ⁇ -glucose.
• Dextrin may be prepared by itself or a commercially available product may be used.
• known starches such as corn, waxy corn, wheat, rice, waxy rice, waxy miro, beans (broad beans, mung beans, red beans, etc.), potatoes, sweet potatoes, tapioca, etc. It can be prepared by hydrolysis by a known method.
• examples of commercially available dextrin include TK-16 (manufactured by Matsutani Chemical Industry Co., Ltd.) and the like, which can be preferably used.
• the above carbohydrates may be used alone or in combination of two or more.
• the content of the saccharide in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied, but is preferably 5 to 25% by mass with respect to the total amount of the semi-solidified nutrient.
• the protein source is not particularly limited, and known proteins can be used. For example, amino acids, peptides, plant proteins, animal proteins and the like can be mentioned.
• Amino acids include essential amino acids such as valine, leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan, histidine; and glycine, alanine, serine, cysteine, asparagine, glutamine, proline, tyrosine, aspartic acid, glutamic acid, arginine, etc.
• essential amino acids such as valine, leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan, histidine
• glycine alanine, serine, cysteine, asparagine, glutamine, proline, tyrosine, aspartic acid, glutamic acid, arginine, etc.
• modified amino acids such as 4-hydroxyproline, 5-hydroxylysine, ⁇ -carboxyglutamic acid, O-phosphoserine, O-phosphotyrosine, N-acetylserine, N ⁇ -methylarginine, pyroglutamic acid, M-formylmethionine; ornithine Special amino acids such as citrulline, ⁇ -aminobutyric acid (GABA), thyroxine, S-adenylmethionine may also be included.
• the amino acids may be stereoisomers (enantiomers, diastereomers), positional isomers, or a mixture thereof.
• the amino acid may be in the form of an inorganic acid salt (hydrochloride or the like), an organic acid salt (acetate or the like), or an ester body (methyl ester or the like) that can be hydrolyzed in vivo.
• the peptide one obtained by polymerizing two or more of the above amino acids via a peptide bond (amide bond) can be used.
• the peptide may be a dipeptide, a tripeptide, an oligopeptide (having about 10 amino acids), or a polypeptide (having several tens to several hundred amino acids).
• Some oligopeptides such as lactotripeptides, casein decapeptides, valyltyrosine-containing sadden peptides and the like may have health functions such as antihypertensive action.
• plant proteins examples include proteins contained in grains such as rice and beans such as soybeans and tofu.
• soy protein it can have health functions, such as combining with a bile acid and promoting the excretion of cholesterol.
• animal proteins examples include proteins contained in eggs, meat, seafood, milk and the like.
• whey protein made from milk (whey) as a raw material, casein protein contained in milk, and soybean protein are preferably used, and whey protein is more preferably used.
• whey protein examples include whey protein concentrate (WPC), whey protein isolate (WPI), hydrolyzed whey peptide (WPH) and the like.
• WPC whey protein concentrate
• WPI whey protein isolate
• WPH hydrolyzed whey peptide
• Commercially available products such as WPC, WPI, and soy protein may be used.
• WPI18855 (manufactured by Fontera), WPI18822 (manufactured by Fontera), WPI1895 (manufactured by Fontera), WPC392 (manufactured by Fontera) ), WPC80 (manufactured by Fontera), WPC7009 (manufactured by Fontera), WPC164 (manufactured by Fontera), WPC162 (manufactured by Fontera), WPC132 (manufactured by Fontera), WPC472 (manufactured by Fontera), Prolina 900 (Fuji Oil) New Fuji Pro 3000 (Fuji Oil Co., Ltd.), New Fuji Pro 1700N (Fuji Oil Co., Ltd.) and the like.
• the above protein sources may be used alone or in combination of two or more.
• the content of the protein source in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied, but is preferably 1 to 18% by mass with respect to the total amount of the semi-solidified nutrient.
• Lipids can be a source of energy, biomembrane constituents, steroid hormones and bile acids.
• the lipid that can be used is not particularly limited, and examples thereof include saturated fatty acids, unsaturated fatty acids, vegetable oils, animal fats and oils, and fish oils.
• saturated fatty acids examples include caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid and the like.
• unsaturated fatty acids include oleic acid, palmitoleic acid, linoleic acid, arachidonic acid, ⁇ -linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
• EPA and DHA it can have health functions, such as a blood cholesterol raise inhibitory effect and a neutral fat rise inhibitory effect.
• Vegetable oils include coconut oil, corn oil, cottonseed oil, olive oil, palm oil, palm kernel oil, peanut oil, rapeseed oil, safflower oil (safflower oil), sesame oil, soybean oil, sunflower oil, almond oil, cashew oil, hazelnut Oil, macadamia nut oil, mongolian oil, pecan oil, pine nut oil, pistachio oil, walnut oil, gourd seed oil, buffalo pumpkin oil, pumpkin seed oil, watermelon seed oil, amaranth oil, apricot oil, apple oil, argan oil , avocado oil, babas oil, moringa oil, borneo oil, cape chestnut oil, cocoa butter, carob oil, kofne palm oil, coriander seed oil, dica oil, flaxseed oil, grape seed oil, hemp oil, kapok seed oil, lale mantia oil , Marula oil, Meadow foam oil, mustard oil, Tsumug butter, okra oil, papaya oil, perilla oil
• Animal fats include lard (pig fat), head (tallow), milk fat, and the like.
• Fish oil includes fish oil such as mackerel, salmon, yellowtail, sardine, saury.
• linoleic acid and ⁇ -linolenic acid that cannot be synthesized in vivo by humans, or lipids containing these.
• lipids may be used alone or in combination of two or more.
• the lipid content in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied, but is preferably 0 to 10% by mass with respect to the total amount of the semi-solidified nutrient.
• vitamin Vitamins are a general term for organic compounds other than carbohydrates, protein sources, and lipids that are necessary to maintain the nutritional state of living organisms.
• Vitamin A retinol
• vitamin D ergocalciferol, cholecalciferol
• vitamin E tocopherol, tocotrienol
• vitamin K phytoquinone, menaquinone
• vitamin B1 thiamine
• vitamin B2 Roboflavin
• vitamin B3 niacin
• vitamin B5 pantothenic acid
• vitamin B6 pyridoxal, pyridoxamine, pyridoxine
• vitamin B7 biotin
• vitamin B9 folic acid
• vitamin B12 cyanocobalamin, hydroxocobalamin
• vitamin C water-soluble vitamins such as (ascorbic acid).
• the content of vitamins in the semi-solidified nutrient can be adjusted as appropriate by the subject to be applied. Normally, fat-soluble vitamins are added in an amount that does not cause excess disease, and water-soluble vitamins are not limited in the amount added.
• the preferable content of each vitamin per 100 g of the semi-solidified nutrient is as follows.
• Vitamin A preferably 0 to 3000 ⁇ g, more preferably 20 to 200 ⁇ g Vitamin D: preferably 0.1-50 ⁇ g, more preferably 0.1-5.0 ⁇ g Vitamin E: preferably 0.2 to 800 mg, more preferably 1 to 10 mg Vitamin K: preferably 0.5 to 1000 ⁇ g, more preferably 2 to 50 ⁇ g Water-soluble vitamins; Vitamin B1: preferably 0.01 to 40 mg, more preferably 0.1 to 5 mg Vitamin B2: preferably 0.01-20 mg, more preferably 0.05-5 mg Niacin: preferably 0.1 to 300 mg NE, more preferably 0.5 to 30 mg NE Pantothenic acid: preferably 0.1 to 55 mg, more preferably 0.2 to 10 mg Vitamin B6: preferably 0.01-60 mg, more preferably 0.1-10 mg Biotin: preferably 0.1 to 1000 ⁇ g, more preferably 1 to 100 ⁇ g Folic acid: preferably 1-1000 ⁇ g, more preferably 10-200 ⁇ g Vitamin B12: preferably 0.01-100 ⁇ g, more
• Minerals include quasi-major elements such as sodium, potassium, calcium, phosphorus and magnesium; essential trace elements such as iron, zinc, copper, iodine, manganese, selenium, chromium and molybdenum. These minerals may be used alone or in combination of two or more.
• the content of mineral in the semi-solidified nutrient can be adjusted as appropriate by the subject to be applied.
• the preferable content of each mineral per 100 g of the semi-solidified nutrient is as follows.
• Dietary fiber can have functions such as reduced nutrient utilization, reduced plasma cholesterol, improved blood glucose response, improved colon function, and prevention of colon cancer.
• dietary fiber may be fermented by intestinal bacteria and converted to short chain fatty acids, carbon dioxide gas, hydrogen gas, methane gas, and the like. Among these, since short chain fatty acids are absorbed in the large intestine, dietary fiber may be an energy source.
• the dietary fiber is not particularly limited, but insoluble dietary fiber such as cellulose, hemicellulose, lignin, insoluble pectin, chitin, chitosan, indigestible dextrin, polydextrose, guar gum degradation product, psyllium seed coat, low molecular weight sodium alginate; Water-soluble dietary fiber such as sex pectin, guar gum, konjac mannan, glucomannan, alginic acid, agar, chemically modified polysaccharide, polydextrose, indigestible oligosaccharide, maltitol, inulin, carrageenan, wheat bran, pine fiber C, etc. Can be mentioned. These dietary fibers may be used alone or in combination of two or more.
• the content of dietary fiber in the semi-solidified nutrient can be adjusted as appropriate by the subject to be applied.
• the semi-solidified nutrient according to the present invention contains moisture.
• the water content in the semi-solidified nutrient can be adjusted as appropriate depending on the subject to be applied and the desired viscosity, but is preferably 40 to 90% by mass with respect to the total amount of the semi-solidified nutrient.
• the semi-solidified nutrient according to this embodiment contains 0.1 to 0.8% by mass, preferably 0.3 to 0.6% by mass of agar, based on the total amount of the semi-solidified nutrient.
• the semi-solidified nutrient contains agar with the above-mentioned content together with a predetermined amount of thickener, water retention can be improved and water separation can be suppressed.
• Agar is a product obtained by freezing and drying mucus of red algae such as agaric and tiger beetle, and contains polysaccharides such as agarose and agaropectin as a main component.
• the agarose and agaropectin have a structure in which galactose and 3,6-andehydrogalactose are alternately polymerized.
• Agar may have different properties depending on the degree of polymerization and molecular weight of agarose and agaropectin, the content of sulfate groups and pyruvate groups in the agar, etc., but it is not particularly limited in the semi-solidified nutrient according to this embodiment. Any of these may be used.
• the semi-solidified nutrient tends to be in a jelly shape close to a solid.
• the semi-solidified nutrient tends to be a paste that is close to a liquid.
• Examples of commercially available products include Ultra Agar UX30 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar UX100 (manufactured by Ina Food Industry Co., Ltd.), Ultra Agar AX-30 (manufactured by Ina Food Industry Co., Ltd.), and Ultra Agar AX-100 ( Ina Food Industry Co., Ltd.), Ultra Agar BX-30 (Ina Food Industry Co., Ltd.), Ultra Agar BX-100 (Ina Food Industry Co., Ltd.) and the like can be used.
• the semi-solidified nutrient according to the present invention includes at least one thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum.
• the content of at least one thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum in the semi-solidified nutrient is 0.2 with respect to the total amount of the semi-solidified nutrient. It is -1.0 mass%. If the content of the thickener is less than 0.2% by mass, it is difficult to maintain water retention and water separation occurs. When the content of the thickener exceeds 1.0% by mass, stickiness tends to increase. The content is preferably 0.3 to 0.6% by mass.
• the semi-solidified nutrient according to this embodiment may further contain a thickener other than the above thickener.
• thickeners examples include, but are not limited to, gelatin, konjac mannan, xanthan gum, tamarind gum, carrageenan, propylene glycol, carboxymethylcellulose gellan gum, gellan gum, tara gum, tamarind seed gum, psyllium seed gum, gum arabic, curd Orchid, pullulan, sodium alginate, tragacanth gum, karaya gum, bee gum and the like can be used. These thickeners may be used alone or in admixture of two or more.
• the semi-solidified nutrient according to this embodiment may further contain other known components such as health functional ingredients, food additives, thickeners and the like.
• a health function component is a component that exhibits a certain function for a living body when ingested.
• the health function component include indigestible oligosaccharide, sugar alcohol, calcium citrate malate (CCM) and casein phosphopeptide (CPP), chitosan, L-arabinose, guava leaf polyphenol, wheat albumin, beans
• CCM calcium citrate malate
• CPP casein phosphopeptide
• chitosan L-arabinose
• guava leaf polyphenol guava leaf polyphenol
• wheat albumin beans
• drum extract diacylglycerol, diacylglycerol plant sterol, soy isoflavone, and milk basic protein.
• Indigestible oligosaccharides are saccharides that are not as large in molecular weight as polysaccharides (about 300 to 3000) among compounds in which monosaccharides are linked by glycosidic bonds.
• the indigestible oligosaccharides are not degraded by human digestive enzymes, but those digested by human digestive enzymes can be included in the aforementioned carbohydrates. Ingestion of indigestible oligosaccharides can provide a bowel regulation effect.
• the indigestible oligosaccharide is not particularly limited, and examples thereof include xylooligosaccharide, fructooligosaccharide, soybean oligosaccharide, isomaltooligosaccharide, dairy oligosaccharide, lactulose, and galactooligosaccharide. These indigestible oligosaccharides may be used alone or in combination of two or more.
• the content of indigestible oligosaccharides in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied.
• Sugar alcohol is a kind of sugar produced by reduction of the carbonyl group of aldose or ketose, and it is not easily absorbed from the small intestine into the body and does not easily become calories. Sugar alcohol is difficult to be metabolized to acid by oral bacteria and can prevent plaque formation. The sugar alcohol can be used as a low calorie sweetener.
• sugar alcohols examples include erythritol, maltitol, palatinose and the like. These sugar alcohols may be used alone or in admixture of two or more.
• the content of sugar alcohol in the semi-solidified nutrient can be adjusted as appropriate by the subject to be applied.
• CCM and CPP can promote calcium absorption and promote bone formation.
• the CCM and CPP may be used alone or in combination.
• CCM and CPP are preferably used in combination with calcium.
• the content of CCM and CPP in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied.
• Food additive The food additive is used for the purpose of processing or storing the food by adding, mixing, moistening or other methods to the food.
• food additives for example, zinc gluconate and copper gluconate, ascorbic acid 2-glucoside, cyclodextrin, antioxidant, colorant, sweetener, pH adjuster, acidulant, An emulsifier, a fragrance
• Zinc gluconate and copper gluconate are gluconates that utilize high chelating ability of gluconate with heavy metal ions. Since it becomes easy to be absorbed when it is made into the form of gluconate, zinc and copper can be absorbed effectively.
• the zinc gluconate and copper gluconate may be used alone or in combination.
• the content of zinc gluconate and copper gluconate in the semi-solidified nutrient can be adjusted as appropriate by the subject to be applied.
• Ascorbic acid 2-glucoside is a compound in which glucose is bonded to the hydroxyl group at the 2-position of vitamin C (ascorbic acid) in an ⁇ -coordination, and is not subject to oxygen attack. It is a vitamin C derivative with high stability. Vitamin C can be efficiently absorbed by ascorbic acid 2-glucoside.
• the content of ascorbic acid 2-glucoside in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied.
• Cyclodextrin is a cyclic oligosaccharide having a cyclic structure in which glucose is bound by a glucoside bond. Those consisting of 6 glucoses are called ⁇ -cyclodextrin, those consisting of 7 glucoses are called ⁇ -cyclodextrin, and those consisting of 8 glucoses are called ⁇ -cyclodextrin. Cyclodextrins can have functions such as an allergy suppressing effect, a blood sugar level increase suppressing effect, and an emulsifying action. The said cyclodextrin may be used independently or may be used in mixture of 2 or more types.
• the content of cyclodextrin in the semi-solidified nutrient can be appropriately adjusted depending on the subject to be applied.
• Antioxidant has the function of preventing alteration of semi-solidified nutrient due to oxidation.
• the antioxidant is not particularly limited, but ascorbic acid and its sodium salt, erythorbic acid and its sodium salt, and the like can be used. These antioxidants may be used alone or in combination of two or more.
• Colorant has a function of beautifying the semi-solidified nutrient.
• dye Edible red No. 2, No. 3, No. 40, No. 102, No. 104, No. 105, and No. 106, Edible blue No. 1 and No. 2, Edible yellow No. 4 And No. 5, Edible Green No.
• ⁇ -carotene water-soluble anato, chlorophyll derivatives (chlorophyll a, chlorphyll b, copper chlorophyll, copper chlorophyllin sodium, iron chlorophyllin sodium, etc.), riboflavin, iron sesquioxide, titanium dioxide Safflower yellow pigment, cochineal pigment, gardenia yellow pigment, turmeric pigment, red cabbage pigment, beet red, grape skin pigment, paprika pigment, caramel and the like can be used. These colorants may be used alone or in admixture of two or more.
• Sweetener The sweetener has a function of imparting sweetness to the semi-solidified nutrient.
• the sweetener is not particularly limited, but saccharin and its sodium salt, xylitol, aspartame, sucralose, acesulfame potassium, dulcin, cyclamate, neotame, trehalose, erythritol, maltose, para-north, sorbitol, licorice extract
• saccharin and its sodium salt xylitol, aspartame, sucralose, acesulfame potassium, dulcin, cyclamate, neotame, trehalose, erythritol, maltose, para-north, sorbitol, licorice extract
• Stevia processed sweeteners thaumatin, curculin, disodium glycyrrhizinate and the like can be used. These sweeteners may be used alone or in combination of two or more.
• the pH adjuster has a function of adjusting the pH of the semi-solidified nutrient.
• the pH adjuster is not particularly limited, and citric acid, gluconic acid, succinic acid, potassium carbonate, sodium hydrogen carbonate, carbon dioxide, lactic acid, sodium lactate, sodium citrate, adipic acid and the like can be used. These pH adjusters may be used alone or in combination of two or more.
• Acidulant has functions such as imparting acidity to the nutrient, preventing oxidation of the food, and adjusting the pH.
• the acidulant is not particularly limited, but acetic acid, citric acid, succinic acid, lactic acid, malic acid, tartaric acid, gluconic acid, phosphoric acid and the like can be used. These acidulants may be used alone or in combination of two or more.
• Emulsifier has functions such as improving the solubility of oil-soluble components such as lipids in water.
• the emulsifier is not particularly limited, and examples include natural emulsifiers such as lecithin, saponin, and casein sodium; and synthetic emulsifiers such as glycerin fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester, and sucrose fatty acid ester. These emulsifiers may be used alone or in combination of two or more.
• the fragrance has a function of flavoring and smelling the semi-solidified nutrient.
• the fragrance is not particularly limited, but acetophenone, ⁇ -amylcinnamaldehyde, anisaldehyde, benzaldehyde, benzyl acetate, benzyl alcohol, cinnamaldehyde, cinnamic acid, citral, citronellal, citronellol, decanal, decanol, ethyl acetoacetate, Ethyl cinnamate, ethyl decanoate, ethyl vanillin, eugenol, geraniol, isoamyl acetate, isoamyl butyrate, isoamyl phenyl acetate, dl-menthol, l-menthol, methyl salicylate, piperonal, propionic acid, terpineol, vanillin, d-borneol, etc. Can be mentioned. These fragrances may be used alone or in combination of two or more.
• enzymes such as ⁇ -amylase, ⁇ -amylase, glucoamylase, glucose isomerase, trehalose producing enzyme, trehalose releasing enzyme, glutaminase, yeast and the like can be used.
• the content of the above-mentioned food additive in the semi-solidified nutrient can be adjusted as appropriate by the target person to be applied.
• the semi-solidified nutrient according to this embodiment suppresses generation of water separation by containing at least one thickener selected from the group consisting of a predetermined amount of pectin, locust bean gum, soybean polysaccharide, and guar gum. be able to.
• the water separation rate of the semi-solidified nutrient is preferably 1% or less, and more preferably 0.5% or less. A water separation rate of 1% or less is preferable because the viscosity and shape retention of a semi-solidified nutrient that is suitably set according to the application can be maintained.
• the value measured by the method described in the Example shall be employ
• the viscosity of the semi-solidified nutrient according to this embodiment is preferably 10,000 to 50,000 mPa ⁇ s, more preferably 15,000 to 30,000 mPa ⁇ s at 25 ° C. It is preferable that the semi-solidified nutrient has a viscosity of 10,000 mPa ⁇ s or more because gastroesophageal reflux, aspiration pneumonia, and the like can be less likely to occur. On the other hand, it is preferable that the viscosity of the semi-solidified nutrient is 50000 mPa ⁇ s or less because digestion can be facilitated.
• the viscosity can be adjusted mainly by the content of at least one thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum in the semi-solidified nutrient.
• at least one thickener selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum in the semi-solidified nutrient.
• viscosity is a value measured by the method described in the examples.
• the calorific value of the semi-solidified nutrient according to this embodiment varies depending on the use of the semi-solidified nutrient, but is preferably 0.5 to 2.5 kcal / g, and is 0 from the viewpoint of water management safety. More preferably, it is 0.5 to 1.0 kcal / g, but more preferably 1.0 to 2.5 kcal / g when it is administered to a patient with water limitation or a burn patient.
• heat amount can be adjusted by setting suitably addition amount, such as saccharide
• the pH of the semi-solidified nutrient according to this embodiment is preferably 3.0 to 4.5, and more preferably 3.5 to 3.9. If pH is in the said range, since the proliferation of bacteria can be suppressed and a refreshing feeling can be obtained, it is preferable.
• the said pH can be adjusted by setting suitably addition amount, such as a pH adjuster and a sour agent.
• pH is a value measured by the method described in the examples.
• the semi-solidified nutrient described above can be applied to fields such as medicine and food.
• the administration method of the semi-solidified nutrient in enteral nutrition is not particularly limited, but is usually oral administration or administration using gastrostomy. Oral administration can be applied to elderly people and patients who have difficulty in chewing and swallowing and whose intestines are functioning. In addition, administration using a gastrostoma can be targeted to elderly people or patients who have difficulty in oral intake and have a functioning intestine.
• the semi-solidified nutrient includes nutrients, moisture, and at least one thickener selected from the group consisting of a predetermined amount of pectin, locust bean gum, soybean polysaccharide, and guar gum. It is preferable that the content of the nutrient is contained in an amount capable of satisfying demands such as calories and nitrogen sources required by the living body intended for enteral nutrition. Moreover, it is preferable to set the water content of the semi-solidified nutrient in consideration of the conditions of elderly people and patients to be administered, water management, and the like.
• the components that can be added in addition to the components essential to the semi-solidified nutrient according to the present embodiment are not particularly limited, and are appropriately set according to the administration method, the state of the elderly or patient to which the semi-solidified nutrient is applied Can be done.
• the state of the elderly or patient to which the semi-solidified nutrient is applied Can be done.
• sweeteners, acidulants, fragrances and the like from the viewpoint of improving the taste at the time of ingestion, and in the case of administration using a gastrostoma, from the viewpoint of preventing discomfort at the time of getp.
• the patient who needs whole body management contains the vitamin and mineral required in order to maintain a nutritional state.
• the semi-solidified nutrient since the occurrence of water separation is suppressed, the semi-solidified nutrient is absorbed with a desired kinetics, and it may be difficult to cause gastroesophageal reflux and aspiration pneumonia. .
• preservability and handling at the time of injection of a gastrostomy tube in administration using a gastrostoma can be improved.
• the semi-solidified nutrient according to the present embodiment can adjust the viscosity, calorie, pH and the like while suppressing the occurrence of water separation, for example, administration using a gastrostoma by adjusting the viscosity Can improve the adhesion to the gastrostomy tube and the digestibility of the semi-solidified nutrient.
• administration using a gastrostoma by adjusting the viscosity Can improve the adhesion to the gastrostomy tube and the digestibility of the semi-solidified nutrient.
• by adjusting the amount of heat nutrition management of elderly people and patients to which the semi-solidified nutrient is applied can be facilitated.
• preservability and a refreshing feeling can be improved by adjusting pH.
• the viscosity, heat amount, pH and the like can be controlled by appropriately adjusting the components in the semi-solidified nutrient and the content thereof.
• production of water separation can be suppressed by including a predetermined amount of thickener.
• the semi-solidified nutrient can be applied to a favorite food, for example.
• the semi-solidified nutrient according to this embodiment includes nutrients, moisture, and a predetermined amount of thickener.
• the content of the nutrient is preferably selected as appropriate according to the intended consumer. That is, when it is set as a diet food, the content of nutrients can be set low, and when it is set as a nutritionally adjusted food that replaces meals, the content of nutrients can be set high.
• the water content of the semi-solidified nutrient can be selected as appropriate in consideration of the texture and whereabouts of the food to be produced.
• the components that can be added in addition to the components essential to the semi-solidified nutrient according to the present invention are not particularly limited, and can be appropriately selected according to the food to be manufactured.
• a pH adjuster to make the pH acidic.
• CCM calcium citrate malate
• CCPP casein phosphopeptide
• the semi-solidified nutrient according to this embodiment since the occurrence of water separation can be suppressed, energy and the like can be suitably supplied, and the food can be excellent in palatability.
• the semi-solidified nutrient according to the present embodiment can adjust the viscosity, calorie, pH and the like while suppressing the occurrence of water separation, various product development can be performed according to the purpose. For example, by adjusting the viscosity, a semi-solidified nutrient having a different texture can be produced. Moreover, the semi-solidification nutrient according to a request can be manufactured by adjusting calorie
• the semi-solidified nutrient according to this embodiment can be produced by a known method. For example, it can be produced by adding nutrients, agar, thickener and other desired components to warm water and stirring. Also, prepare a solution in which agar is dissolved in warm water and a solution in which a thickener is dissolved in warm water, add nutrients and other desired ingredients to any of the two solutions, It can be produced by mixing and stirring.
• the obtained semi-solidified nutrient can be commercialized by, for example, filling a container after continuous sterilization. Although it does not restrict
• UHT Ultra high temperature short time
• the sterilization is preferably performed in a short time. By performing sterilization in a short time, deterioration of components contained in the semi-solidified nutrient can be suppressed.
• the container for filling the semi-solidified nutrient is not particularly limited, and a known container can be used.
• the container include a tetrapack, a cart can, a glass container, a metal can, an aluminum pouch, and a plastic container. Of these, it is preferable to use a plastic container.
• polyethylene polyethylene
• PP polypropylene
• PVC polyvinyl chloride
• PVAc polyvinyl acetate
• PC polycarbonate
• PBT polybutylene terephthalate
• PET polyethylene terephthalate
• PEN Polyethylene naphthalate
• EVA ethylene-vinyl acetate copolymer
• EVA ethylene- ⁇ -olefin copolymer
• polyfluorocarbon polyimide and the like
• the plastic container further includes polyethylene terephthalate (PET), polyethylene naphthalate (PEN), ethylene-vinyl alcohol copolymer (EVOH), polyvinylidene chloride (PVDC), polyacrylonitrile, polyvinyl alcohol, polyamide, polyester, and the like.
• Gas barrier resin layer Gas barrier inorganic layers such as an aluminum foil, an aluminum vapor deposition film, a silicon oxide film, and an aluminum oxide film may be used in appropriate combination. By providing the gas barrier layer, deterioration of the semi-solidified nutrient due to oxygen, water vapor, or the like can be prevented.
• the container may be further shielded from light.
• the light shielding for example, deterioration due to light such as vitamin A, vitamin B2, vitamin C, and vitamin K that can be contained in the semi-solidified nutrient can be suppressed.
• the above-mentioned container may use what is marketed, for example, a soft pouch (made by Fuji Seal Co., Ltd.), a bottled pouch (made by Toppan Printing Co., Ltd.), a spouch (made by Dai Nippon Printing Co., Ltd.), a cheer pack (Co., Ltd.) Hosokawa Yoko) etc. can be used.
• a soft pouch made by Fuji Seal Co., Ltd.
• a bottled pouch made by Toppan Printing Co., Ltd.
• a spouch made by Dai Nippon Printing Co., Ltd.
• a cheer pack Co., Ltd. Hosokawa Yoko
• Example 1 1200 parts of the prepared water was put in a 5 L stainless steel bucket and heated to 80 ° C. or higher in a hot water bath. Next, 15 parts of Ultra Agar UX100 (manufactured by Ina Food Industry Co., Ltd.), 2 parts of pectin, 6 parts of locust bean gum, 2.5 parts of soybean polysaccharide, and 1 part of guar gum were added and dissolved. The obtained solution was cooled to 50 to 60 ° C., 150 parts of WPC392 (whey protein concentrate: manufactured by Fonterra) as a protein source, and TK-16 (dextrin: manufactured by Matsutani Chemical Co., Ltd.) as a carbohydrate 400 Parts were added.
• WPC392 whey protein concentrate: manufactured by Fonterra
• TK-16 dextrin: manufactured by Matsutani Chemical Co., Ltd.
• the obtained solution was subjected to continuous sterilization, filled in an aluminum pouch with a stopper so that the amount was 200 parts per piece, and subjected to container sterilization at 90 ° C. for 10 minutes. After the container sterilization treatment, a semi-solidified nutrient containing a pouch was produced by cooling.
• Example 2 A semi-solid nutrient was produced in the same manner as in Example 1 except that the protein source was changed to 120 parts of WPC392 (whey protein concentrate: manufactured by Fonterra) and 30 parts of soy protein.
• WPC392 whey protein concentrate: manufactured by Fonterra
• Example 3 20 parts agar added, 4 parts pectin added, 10 parts locust bean gum added, 2.5 parts soy polysaccharide added, and 1.5 parts guar gum added A semi-solidified nutrient was produced in the same manner as in Example 1 except that.
• Example 1 40 parts of agar, 1.5 parts of pectin, 0.5 parts of locust bean gum, 2 parts of soy polysaccharide, and 0.5 parts of guar gum A semi-solidified nutrient was produced in the same manner as in Example 1 except that the content was changed to.
• the evaluation of the water separation rate is based on a semi-solidified nutrient that was allowed to stand for 24 hours at 25 ° C and a semi-solidified nutrient that was subjected to an accelerated test (stable for 4 weeks at 40 ° C) that assumed storage for 7 months and a half. I went for both.
• ⁇ Viscosity> The viscosity of the semi-solidified nutrient was measured using a B-type viscometer DV-II + Pro (manufactured by Brookfield). The measurement was performed for 1 minute under conditions of room temperature (25 ° C.) and a rotation speed of 6 rpm.
• ⁇ Nutrient when ejected from the container has a smooth cream state
• ⁇ Slight roughness and partial aggregation are observed in the nutrient when ejected from the container
• ⁇ Nutrient when ejected from the container Large aggregates and lumps are seen.
• ⁇ Stickiness> A 50 mL catheter tip syringe filled with a semi-solid nutrient is connected to a tube with an inner diameter of 4 mm, and the entire amount of the semi-solid nutrient is extruded from the syringe. Stickiness was evaluated according to the degree. The stickiness was evaluated according to the following criteria.
• the semi-solidified nutrients of the examples contain a predetermined amount of at least one selected from the group consisting of pectin, locust bean gum, soybean polysaccharide, and guar gum. It can be seen that the occurrence of water separation is suppressed and the smooth cream-like properties can be maintained.

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• 2012
  • 2012-07-06 TW TW101124590A patent/TW201336428A/zh unknown
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