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WO2013186735A3 - In-vivo tissue imaging by photothermal detection - Google Patents

In-vivo tissue imaging by photothermal detection Download PDF

Info

Publication number
WO2013186735A3
WO2013186735A3 PCT/IB2013/054849 IB2013054849W WO2013186735A3 WO 2013186735 A3 WO2013186735 A3 WO 2013186735A3 IB 2013054849 W IB2013054849 W IB 2013054849W WO 2013186735 A3 WO2013186735 A3 WO 2013186735A3
Authority
WO
WIPO (PCT)
Prior art keywords
vivo tissue
tissue imaging
photothermal detection
vivo
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2013/054849
Other languages
French (fr)
Other versions
WO2013186735A2 (en
Inventor
Moshe Prof. SINVANI
Zeev Prof. ZALEVSKY
Rachela Dr. POPOVTZER
Kobi JAKOBSOHN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bar Ilan Research and Development Co Ltd
Original Assignee
Bar Ilan Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bar Ilan Research and Development Co Ltd filed Critical Bar Ilan Research and Development Co Ltd
Publication of WO2013186735A2 publication Critical patent/WO2013186735A2/en
Publication of WO2013186735A3 publication Critical patent/WO2013186735A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04NPICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/20Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from infrared radiation only
    • H04N23/23Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from infrared radiation only from thermal infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention provides a method and a system for in-vivo a imaging a tissue with gold nanoparticles inserted therein, the said system and method are based on: a composition of cellular gold nanoparticles, an irradiation device (preferably a 650-900nm laser device) configure to selectively increase the temperature of the nanoparticles and a thermal imaging camera configure to in-vivo Image the tissue.
PCT/IB2013/054849 2012-06-14 2013-06-13 Photothermal detection Ceased WO2013186735A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261659444P 2012-06-14 2012-06-14
US61/659,444 2012-06-14

Publications (2)

Publication Number Publication Date
WO2013186735A2 WO2013186735A2 (en) 2013-12-19
WO2013186735A3 true WO2013186735A3 (en) 2014-02-20

Family

ID=49758819

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/054849 Ceased WO2013186735A2 (en) 2012-06-14 2013-06-13 Photothermal detection

Country Status (1)

Country Link
WO (1) WO2013186735A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10094823B2 (en) * 2015-01-23 2018-10-09 Tokitae Llc Photothermal spectroscopy assay readers, and related assay kits and methods
US9625385B2 (en) 2015-02-24 2017-04-18 Tokitae Llc Photothermal spectroscopy systems for offset synchronous testing of flow assays and methods of using same
EP3496730B1 (en) 2016-08-14 2022-05-25 Ramot at Tel-Aviv University Ltd. Mesenchymal cell-derived exosomes to treat neurological disorders
CN112236131A (en) 2018-03-29 2021-01-15 技术研究及发展基金有限公司 Vesicles containing PTEN inhibitors and uses thereof
WO2021205459A1 (en) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Cannabidiol-containing compositions and uses thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
WO2003011130A2 (en) * 2001-07-31 2003-02-13 Medisim Ltd. A method for detection of cancer using a thermal enhancement agent, and non-invasive thermal monitoring
WO2003023341A2 (en) * 2001-09-08 2003-03-20 Avecia Limited Thermographic metthod
US20100286674A1 (en) * 2008-01-22 2010-11-11 Board Of Regents, The University Of Texas System Systems, devices and methods for imaging and surgery
TW201039881A (en) * 2009-05-11 2010-11-16 New Vision Inc Laser-excited nanoparticle tumor therapy medical device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
WO2003011130A2 (en) * 2001-07-31 2003-02-13 Medisim Ltd. A method for detection of cancer using a thermal enhancement agent, and non-invasive thermal monitoring
WO2003023341A2 (en) * 2001-09-08 2003-03-20 Avecia Limited Thermographic metthod
US20100286674A1 (en) * 2008-01-22 2010-11-11 Board Of Regents, The University Of Texas System Systems, devices and methods for imaging and surgery
TW201039881A (en) * 2009-05-11 2010-11-16 New Vision Inc Laser-excited nanoparticle tumor therapy medical device

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HUNG X. ET AL.: "Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods", J. AM. CHEM. SOC., vol. 128, no. 6, 21 January 2006 (2006-01-21), pages 2115 - 2120 *
JAKOBSOHN K. ET AL.: "Towards real-time detection of tumor margins using photothermal imaging of immune-targeted gold nanoparticles", INTERNATIONAL JOURNAL OF NANOMEDICINE, vol. 7, 28 August 2012 (2012-08-28), pages 4707 - 4713 *
PERETZ V. ET AL.: "The Effect of Nanoparticle Size on Cellular Binding Probability", JOURNAL OF ATOMIC, MOLECULAR, AND OPTICAL PHYSICS, vol. 2012, 9 April 2012 (2012-04-09) *

Also Published As

Publication number Publication date
WO2013186735A2 (en) 2013-12-19

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