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WO2013177067A3 - Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof - Google Patents

Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof Download PDF

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Publication number
WO2013177067A3
WO2013177067A3 PCT/US2013/041873 US2013041873W WO2013177067A3 WO 2013177067 A3 WO2013177067 A3 WO 2013177067A3 US 2013041873 W US2013041873 W US 2013041873W WO 2013177067 A3 WO2013177067 A3 WO 2013177067A3
Authority
WO
WIPO (PCT)
Prior art keywords
herbal composition
inflammatory diseases
prepare
treatment
gastrointestinal inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/041873
Other languages
French (fr)
Other versions
WO2013177067A2 (en
Inventor
Aiping ZHAO
Kejin ZHU
Wei Xiao
Zhenzhong Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201380026260.XA priority Critical patent/CN104363773B/en
Priority to SG11201407653SA priority patent/SG11201407653SA/en
Publication of WO2013177067A2 publication Critical patent/WO2013177067A2/en
Publication of WO2013177067A3 publication Critical patent/WO2013177067A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Machine Translation (AREA)

Abstract

The present invention relates to a herbal composition to treat gastrointestinal inflammatory diseases in a subject suffering therefrom. The present invention further provides a method to use a pharmaceutical effective amount of the herbal composition to treat Gl inflammatory diseases. Particularly, this invention relates to using a pharmaceutically effective amount of the herbal composition extract having the ability to inhibit the expression of pro-inflammatory cytokines, attenuate disruption of epithelial barrier, and modulate gut function
PCT/US2013/041873 2012-05-19 2013-05-20 Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof Ceased WO2013177067A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201380026260.XA CN104363773B (en) 2012-05-19 2013-05-20 Herbal composition for treating gastrointestinal inflammatory diseases, its preparation method and use
SG11201407653SA SG11201407653SA (en) 2012-05-19 2013-05-20 Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261649287P 2012-05-19 2012-05-19
US61/649,287 2012-05-19

Publications (2)

Publication Number Publication Date
WO2013177067A2 WO2013177067A2 (en) 2013-11-28
WO2013177067A3 true WO2013177067A3 (en) 2014-01-16

Family

ID=49624489

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/041873 Ceased WO2013177067A2 (en) 2012-05-19 2013-05-20 Herbal composition for treatment of gastrointestinal inflammatory diseases and method to prepare and use thereof

Country Status (3)

Country Link
CN (2) CN104363773B (en)
SG (2) SG11201407653SA (en)
WO (1) WO2013177067A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961391A (en) * 2014-04-17 2014-08-06 陈新灵 Medicine composition for treating gastrointestinal psychoneurosis

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435474A (en) * 2014-11-10 2015-03-25 青岛祥翔生物医药科技有限公司 Traditional Chinese medicine for treating gastrointestinal diseases caused by intestinal damp-heat
CN104922350A (en) * 2015-04-29 2015-09-23 金先琦 Traditional Chinese medicine for treating acute enteritis
CN110038107A (en) * 2018-01-14 2019-07-23 青岛市妇女儿童医院 A kind of herb mixture for infantile chronic diarrhea
CN110037294A (en) * 2019-04-12 2019-07-23 吉林省九圣源生物科技有限公司 A kind of herbal cuisine eaten for stomach and enteron aisle ulcer crowd

Citations (1)

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EP1974046A2 (en) * 2006-01-16 2008-10-01 Reliance Life Sciences Pvt., Ltd. Process for increased patchoulol content in essential oil of pogostemon cablin

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CN1251733C (en) * 2002-12-23 2006-04-19 江苏康缘药业股份有限公司 A kind of preparation method of flavored Huoxiang soft capsule
CN100367996C (en) * 2003-12-23 2008-02-13 江苏康缘药业股份有限公司 A kind of quality control method of flavored Huoxiang soft capsule
CN100361693C (en) * 2004-11-04 2008-01-16 贵阳云岩西创药物科技开发有限公司 Health restoring agastache dripping pill preparation and its preparing method
CN100515397C (en) * 2005-07-28 2009-07-22 江西汇仁药业有限公司 Agastachel patchouli qi-righting fast dispersion solid preparation and its preparation method
CN101224266B (en) * 2007-12-29 2011-12-21 天津中新药业集团股份有限公司达仁堂制药厂 Content determination method of HuoXiangZhengQi soft capsule
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EP1974046A2 (en) * 2006-01-16 2008-10-01 Reliance Life Sciences Pvt., Ltd. Process for increased patchoulol content in essential oil of pogostemon cablin

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"Herbal Times Huo Xiang Zheng Qi Wan.", ACU-MARKET, 2009, Retrieved from the Internet <URL:http://www.acu-market.com/Huo-Xiang-Zheng-Qi-Wan/productinfo/1760> [retrieved on 20130924] *
BAKKALI, F ET AL.: "Biological Effects Of Essential Oils: A Review.", FOOD AND CHEMICAL TOXICOLOGY., vol. 46, 29 September 2007 (2007-09-29), pages 446 - 475 *
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KAWASHIMA, K ET AL.: "Pharmacological Properties Of Traditional Medicine (XXIX): Effect Of Hange-shashin-to And The Combinations Of Its Herbal Constituents On Rat Experimental Colitis.", BIOL. PHARM. BULL., vol. 27, no. 10, October 2004 (2004-10-01), pages 1599 - 1603 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961391A (en) * 2014-04-17 2014-08-06 陈新灵 Medicine composition for treating gastrointestinal psychoneurosis
CN103961391B (en) * 2014-04-17 2016-08-31 陈新灵 A kind of pharmaceutical composition treating gastrointestinal neurosis

Also Published As

Publication number Publication date
SG10201706453XA (en) 2017-09-28
CN104363773B (en) 2017-03-01
SG11201407653SA (en) 2014-12-30
CN104363773A (en) 2015-02-18
CN106511949A (en) 2017-03-22
WO2013177067A2 (en) 2013-11-28

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