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WO2013176112A1 - Procédé de production d'image ultrasonore et dispositif de diagnostic d'image ultrasonore - Google Patents

Procédé de production d'image ultrasonore et dispositif de diagnostic d'image ultrasonore Download PDF

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Publication number
WO2013176112A1
WO2013176112A1 PCT/JP2013/064046 JP2013064046W WO2013176112A1 WO 2013176112 A1 WO2013176112 A1 WO 2013176112A1 JP 2013064046 W JP2013064046 W JP 2013064046W WO 2013176112 A1 WO2013176112 A1 WO 2013176112A1
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Prior art keywords
image
ultrasonic
element data
region
interest
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PCT/JP2013/064046
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English (en)
Japanese (ja)
Inventor
公人 勝山
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Fujifilm Corp
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Fujifilm Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
    • A61B8/467—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means
    • A61B8/469—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means for selection of a region of interest
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Definitions

  • the present invention relates to an ultrasonic image generation method and an ultrasonic image diagnostic apparatus that perform imaging of an organ or the like in a living body by transmitting and receiving ultrasonic waves to generate an ultrasonic diagnostic image used for diagnosis.
  • ultrasonic diagnostic apparatus using an ultrasonic image
  • this type of ultrasonic diagnostic apparatus has an ultrasonic probe (ultrasonic probe) having a built-in transducer array, and an apparatus main body connected to the ultrasonic probe.
  • Ultrasound images are transmitted by transmitting ultrasonic waves from the probe to the subject, receiving ultrasonic echoes from the subject with the ultrasonic probe, and processing the received signals electrically with the device body Is generated.
  • the ultrasonic diagnostic apparatus when generating an ultrasonic image, the ultrasonic image is generated on the assumption that the sound speed in the living body of the subject is constant. However, in the actual living body, the sound speed value changes depending on the properties of the tissue in the living body, so the sound speed value varies. Due to this variation, the ultrasonic image has spatial distortion, contrast, or spatial resolution. Image quality degradation such as lowering of image quality. On the other hand, in recent years, in order to more accurately diagnose a diagnostic part in a subject, the sound velocity value at an arbitrary diagnostic part is optimized, and such image distortion and reduction in spatial resolution are reduced. Has been made to improve.
  • Patent Document 1 includes an evaluation unit that calculates an evaluation value indicating the degree of variation based on a plurality of pieces of phase information obtained for all or part of a plurality of received signals after delay processing and before addition processing. It is described that an optimum sound speed value is obtained by having a determination means for determining an optimum value as the sound speed parameter value based on a change in the evaluation value when the sound speed parameter value is varied. It is described that the spatial resolution of an ultrasonic image is improved by generating an ultrasonic image using the. It also describes that an optimum sound speed value is obtained based on the degree of variation in phase information of a plurality of received signals after delay processing and before addition in a region of interest (ROI) set by the operator.
  • ROI region of interest
  • the region of interest in the ultrasound image By setting the region of interest in the ultrasound image and obtaining the optimum sound velocity value in the region of interest, it is possible to prevent distortion of the image of the region of interest, i.e., tissue or lesion that you want to see, and improve spatial resolution.
  • the optimal sound speed value that takes time to calculate can be obtained in a short time, and the time required for calculation can be shortened.
  • the focus of interest set by the operator is not in focus, the received data in the focus of interest is greatly distorted, and an optimal sound speed value may not be obtained. Therefore, even if an ultrasonic image is generated with the obtained sound velocity value, the quality of the image of the region of interest may not be sufficiently improved.
  • An object of the present invention is to solve the above-mentioned problems of the prior art, reduce the time required for measurement and calculation of the optimum sound speed value, obtain a more accurate optimum sound speed value in the attention area, and improve the image quality of the attention area.
  • An object of the present invention is to provide an ultrasonic image generation method and an ultrasonic diagnostic imaging apparatus capable of obtaining an ultrasonic image.
  • a transducer array having a plurality of transducers transmits ultrasonic waves to a subject based on a first transmission focus condition, and transmits ultrasonic echoes from the subject.
  • a region of interest setting step for setting a region of interest in the sound wave image and a second element output by transmission based on a second transmission focus condition different from the first transmission focus condition for acquiring the first element data
  • a second element data acquisition step for acquiring data; and an optimum sound speed calculation step for calculating an optimum sound speed value of the region of interest using the second element data corresponding to the region of interest.
  • the transducer array acquires the second element data that is transmitted to the target region of the subject based on the second transmission focus condition and receives and outputs the ultrasonic echo from the subject.
  • the second element data acquisition step is performed before the attention area setting step, and the acquired second element data is stored in the storage unit, and the optimum sound speed calculation step is performed after the attention area setting step.
  • the second element data corresponding to the region of interest is read from the stored second element data, and the optimum sound speed value of the region of interest is calculated.
  • a third transmission condition determining step for determining a third transmission focus condition for transmitting an ultrasonic wave focused on the region of interest based on the calculated optimum sound velocity value; Based on the transmission focus condition, a third element data acquisition step of transmitting ultrasonic waves to the region of interest of the subject and receiving ultrasonic echoes from the subject to acquire third element data, and the calculated optimum sound speed value Based on the acquired third element data, it is preferable to reconstruct an image of the region of interest and generate a reconstructed image.
  • At least one of transmission delay, transmission aperture, transmission apodization, and transmission waveform is different between the first transmission focus condition and the second transmission focus condition.
  • a reconstructed image is generated by reconstructing an image of a reconstruction area that includes the attention area and is wider than the attention area.
  • the present invention has a plurality of transducers, transmits ultrasonic waves to a subject based on predetermined transmission conditions, and receives ultrasonic echoes from the subject.
  • a transducer array that outputs element data that is a reception signal for each transducer, and the transducer array transmits ultrasonic waves to the subject and receives ultrasonic echoes from the subject based on the first transmission focus condition.
  • An image generation unit that generates an ultrasonic image based on a sound ray signal generated from the first element data that is output, a region-of-interest setting unit that sets a region of interest in the generated ultrasonic image, and a first transmission Based on a second transmission focus condition different from the focus condition, the transducer array transmits ultrasonic waves to the region of interest of the subject, receives ultrasonic echoes from the subject, and acquires second element data to be output. Second element data collection And parts, with the second element data acquired, and having an optimal sound velocity calculation unit for calculating an optimum sound speed value in the region of interest to provide an ultrasound system.
  • a second transmission condition determination unit that determines a second transmission focus condition for transmitting an ultrasonic wave focused on the set region of interest.
  • an image reconstruction unit that reconstructs an image of the region of interest from the second element data based on the calculated optimum sound speed value and generates a reconstructed image.
  • a third transmission condition determining unit that determines a third transmission focus condition for transmitting an ultrasonic wave focused on the region of interest, and the transducer array performs the third transmission.
  • a third element data acquisition unit for acquiring third element data for transmitting ultrasonic waves to the region of interest of the subject based on the focus condition, receiving ultrasonic echoes from the subject and outputting them, and third element data; It is preferable to have an image reconstructing unit that reconstructs the image of the region of interest and generates a reconstructed image.
  • the image reconstruction unit includes a reconstruction region setting unit that includes a region of interest and sets a reconstruction region wider than the region of interest, and the image reconstruction unit reconstructs the image of the reconstruction region based on the optimum sound speed value. It is preferable to generate a reconstructed image.
  • the ultrasonic diagnostic imaging apparatus of the present invention having the above-described configuration, the time required for measurement / calculation of the optimum sound speed value is reduced, and more accurate optimum sound speed value is obtained in the attention area, and the image quality of the attention area is good. An ultrasonic image can be obtained.
  • 2 is a flowchart for explaining the operation of the ultrasonic diagnostic imaging apparatus of FIG. 1.
  • 6 is a flowchart for explaining the operation of the ultrasonic diagnostic imaging apparatus of FIG.
  • 6 is a block diagram which shows notionally another example of the ultrasonic diagnosing device which implements the ultrasonic image generation method which concerns on this invention.
  • FIG. 1 is a block diagram conceptually showing the structure of an example of an ultrasonic diagnostic apparatus that implements the ultrasonic image generation method of the present invention.
  • the ultrasonic diagnostic apparatus 10 includes an ultrasonic probe 12, a transmission circuit 14 and a reception circuit 16 connected to the ultrasonic probe 12, an A / D conversion unit 20, an image generation unit 18, and an element data storage unit 22.
  • the attention area setting unit 24, the image regeneration unit 26, the display control unit 32, the display unit 34, the control unit 36, the operation unit 38, the storage unit 40, the second transmission condition determination unit 60, An optimum sound speed acquisition unit 62 and a reconstructed image generation unit 64 are provided.
  • the ultrasonic probe 12 has a transducer array 42 used in a normal ultrasonic diagnostic apparatus.
  • the transducer array 42 has a plurality of ultrasonic transducers arranged one-dimensionally or two-dimensionally. Each of these ultrasonic transducers transmits an ultrasonic beam according to the drive signal supplied from the transmission circuit 14 and picks up an ultrasonic echo from the subject and outputs a reception signal when imaging an ultrasonic image. To do.
  • Each ultrasonic transducer includes, for example, a piezoelectric ceramic represented by PZT (lead zirconate titanate), a polymer piezoelectric element represented by PVDF (polyvinylidene fluoride), and PMN-PT (magnesium niobate / lead titanate). It is constituted by a vibrator in which electrodes are formed at both ends of a piezoelectric body made of a piezoelectric single crystal represented by a solid solution).
  • PZT lead zirconate titanate
  • PVDF polymer piezoelectric element represented by PVDF (polyvinylidene fluoride)
  • PMN-PT magnesium niobate / lead titanate
  • each transducer When a pulsed or continuous wave voltage is applied to the electrodes of such a vibrator, the piezoelectric material expands and contracts, and pulsed or continuous wave ultrasonic waves are generated from the respective vibrators. As a result, an ultrasonic beam is formed.
  • each transducer generates an electric signal by expanding and contracting by receiving propagating ultrasonic waves, and these electric signals are output as ultrasonic reception signals.
  • the transmission circuit 14 includes, for example, a plurality of pulsers, and a plurality of transducer arrays 42 according to a transmission delay pattern set based on a sound speed or a distribution of sound speeds selected according to a control signal from the control unit 36.
  • the delay amount of each drive signal is adjusted and supplied to a plurality of ultrasonic transducers so that ultrasonic waves transmitted from the ultrasonic transducers form ultrasonic beams.
  • the transmission delay pattern is a pattern of the transmission timing of each element. More specifically, the transmission delay pattern is the time until transmission of each element when the transmission time of the central element of the element that performs transmission is 0. It is a pattern of time (delay).
  • the transmission circuit 14 drives the transducer array 42 so as to form an ultrasonic beam in accordance with a first transmission focus condition stored in advance in order to generate an ultrasonic image.
  • the transmission circuit 14 focuses on the attention area according to the second transmission focus condition determined by the second transmission condition determination unit 60 described later.
  • the transducer array 42 is driven so as to form a beam. This will be described in detail later.
  • the receiving circuit 16 receives and amplifies element data for each ultrasonic transducer, which is a reception signal that each ultrasonic transducer of the transducer array 42 receives and outputs an ultrasonic echo from the subject, and outputs an analog element. Data is supplied to the A / D converter 20. The A / D converter 20 converts the analog element data supplied from the receiving circuit 16 into digital element data.
  • the reception signal obtained by transmitting the ultrasonic wave according to the first transmission focus condition for generating the ultrasonic image is set as the first element data, and the ultrasonic wave is transmitted according to the second transmission focus condition.
  • the received signal is assumed to be second element data.
  • the A / D conversion unit 20 supplies the first element data to the first element data acquisition unit 54 of the image generation unit 18.
  • the A / D conversion unit 20 supplies the second element data to the second element data acquisition unit 70 of the optimum sound speed acquisition unit 62 and also supplies the second element data to the element data storage unit 22.
  • the A / D conversion unit 20 may supply not only the second element data but also the first element data to the element data storage unit 22.
  • the image generation unit 18 generates a sound ray signal (reception data) from the first element data supplied from the A / D conversion unit 20, and generates an ultrasonic image from the sound ray signal.
  • the image generation unit 18 includes a first element data acquisition unit 54, a phasing addition unit 44, a signal processing unit 46, a DSC 48, an image processing unit 50, and an image memory 52.
  • the first element data acquisition unit 54 acquires the first element data supplied from the A / D conversion unit 20 under the control of the control unit 36 and supplies the first element data to the phasing addition unit 44.
  • the phasing addition unit 44 selects one reception delay pattern from a plurality of reception delay patterns based on the sound speed or the distribution of sound speeds stored in advance according to the reception direction set in the control unit 36, In accordance with the selected reception delay pattern, the reception focus processing is performed by adding each delay to the element data. By this reception focus processing, reception data (sound ray signal) in which the focus of the ultrasonic echo is narrowed is generated.
  • the phasing addition unit 44 supplies the received data to the signal processing unit 46.
  • the signal processing unit 46 corrects attenuation by distance according to the depth of the reflection position of the ultrasonic wave on the reception data generated by the phasing addition unit 44, and then performs an envelope detection process to perform detection.
  • a B-mode image signal that is tomographic image information related to the tissue in the specimen is generated.
  • a DSC (digital-scan converter) 48 converts the B-mode image signal generated by the signal processing unit 46 into an image signal (raster conversion) according to a normal television signal scanning method.
  • the image processing unit 50 performs various necessary image processing such as gradation processing on the B-mode image signal input from the DSC 48 and then outputs the B-mode image signal to the display control unit 32 or stores it in the image memory 52. Store.
  • the display control unit 32 displays an ultrasonic image on the display unit 34 based on the B-mode image signal subjected to image processing by the image processing unit 50.
  • the display unit 34 includes a display device such as an LCD, for example, and displays an ultrasonic image under the control of the display control unit 32.
  • the element data storage unit 22 sequentially stores digital element data (first element data and second element data) output from the A / D conversion unit 20.
  • the element data storage unit 22 associates information about the frame rate input from the control unit 36 (for example, parameters indicating the depth of the reflection position of the ultrasonic wave, the density of the scanning line, and the visual field width) with the element data. Store.
  • the region-of-interest setting unit 24 sets the region of interest ROI according to the input from the operation unit 38 by the operator.
  • FIG. 2 is a diagram schematically illustrating an example of an ultrasound image in which a region of interest ROI is set.
  • a target region P such as a tissue (organ) or a lesion to be viewed is imaged, and a region of interest ROI is set so as to surround the target region P.
  • the attention area setting unit 24 supplies the information on the set attention area ROI to the second transmission condition determination unit 60.
  • the region-of-interest setting unit 24 is not limited to the configuration in which the region of interest ROI is set according to the input from the operation unit 38, and analyzes the ultrasonic image (B-mode image signal) generated by the image generation unit 18.
  • the region of interest ROI may be set.
  • the region-of-interest setting unit 24 may extract a structure region based on a difference in luminance value between adjacent pixels in the ultrasonic image generated by the image generation unit 18. Specifically, a position (pixel) where the difference in luminance value between adjacent pixels is equal to or greater than a predetermined value is determined as a marginal part (edge) of a structural region (tissue or lesion) and surrounded by edges. Even if a region or a region containing many edges is determined as a structural region, that is, a target portion P and extracted, and a region including the target portion P and having a predetermined shape and size is set as the region of interest ROI Good.
  • the structure region may be regarded as one type of region. Alternatively, it is regarded as two or more types of regions according to edge continuity, luminance value level, etc., each region is determined as a target region P and extracted, and a region of interest ROI is set for each target region P Also good.
  • the second transmission condition determination unit 60 determines a second transmission focus condition for transmitting an ultrasonic beam focused in the region of interest ROI from information on the region of interest ROI supplied from the region of interest setting unit 24. It is a part to do. Specifically, the second transmission condition determination unit 60 sets a plurality of focal points in the region of interest ROI according to the set position and size of the region of interest ROI, and applies an ultrasonic beam to each of the set focal points. A transmission delay pattern for transmission is determined as a second transmission focus condition. Further, the distance between the focal points under the second transmission focus condition is set closer than the distance between the focal points under the first transmission focus condition for capturing an ultrasonic image.
  • the focus position for example, when the depth of the region of interest ROI is 10 mm to 40 mm and the focal interval is set to 4 mm, the focus is set to 10, 14 from the upper end side of the region of interest ROI. , 18, 22, 26, 30, 34, and 38 mm, respectively.
  • the depth of each focal point may be set from the lower end side of the region of interest ROI.
  • the position of the focal point may be set as appropriate based on the set width of the region of interest and the set focal interval.
  • the distance between the focal points under the second transmission focus condition is not limited to being set more densely than the distance between the focal points under the first transmission focus condition, and the focus position is set within the region of interest. If so, the same interval as the interval between the focal points in the first transmission focus condition may be used. Further, the configuration in which a plurality of focal points are set in the region of interest ROI is not limited, and a configuration in which one focal point is set in the region of interest ROI may be adopted. When one focus is set for the region of interest ROI, the focus may be set at the center of the region of interest, or the focus may be set on the edge of the region of interest.
  • the second transmission condition determination unit 60 determines a transmission numerical aperture, transmission apodization (amplitude of transmission wave of each element), and transmission waveform as a transmission condition in order to focus on the region of interest. It is good also as a structure.
  • the second transmission condition determination unit 60 supplies the determined second transmission focus condition to the control unit 36.
  • the optimum sound speed acquisition unit 62 is a part that acquires the optimum sound speed value of the set region of interest ROI under the control of the control unit 36.
  • the optimum sound speed acquisition unit 62 includes a second element data acquisition unit 70 and an optimum sound speed calculation unit 72.
  • the transmission circuit 14 drives the transducer array 42 based on the second transmission focus condition determined by the second transmission condition determination unit 60, and the transducer array 42 transmits an ultrasonic echo. This is a part for acquiring the second element data obtained by reception.
  • the second element data acquisition unit 70 supplies the acquired second element data to the optimum sound speed calculation unit 72.
  • the optimum sound speed calculation unit 72 is a part that calculates an optimum sound speed value in the set region of interest ROI.
  • the optimum sound speed value means that the contrast and / or sharpness of the image becomes the highest when the set sound speed is changed variously and the reception focus process is performed based on the set sound speed to form an ultrasonic image.
  • the set sound speed value For example, as described in JP-A-8-317926, the optimum sound speed value can be determined based on the contrast of the image, the spatial frequency in the scanning direction, the variance, and the like.
  • the optimum sound speed calculation unit 72 changes the set sound speed v from 1400 m / s to 1650 m / s in increments of 50 m / s, and calculates the sharpness of the image of the region of interest ROI at each set sound speed v. That is, the optimum sound speed calculation unit 72 generates a sound ray signal by performing reception focus processing using the second element data corresponding to the region of interest ROI based on the set speed v at each set speed v. An ultrasonic image is formed from the sound ray signal, and the sharpness of the image of the region of interest ROI at each set sound velocity v is calculated.
  • the optimum sound speed calculation unit 72 compares the sharpness values of the images at each set sound speed v, and sets the set sound speed v having the highest obtained sharpness value as the optimum sound speed value.
  • the optimum sound speed calculation unit 72 supplies the calculated optimum sound speed value to the image reconstruction unit 76 of the reconstructed image generation unit 64.
  • the reconstructed image generation unit 64 is a part that reconstructs the image of the region of interest based on the optimum sound speed value under the control of the control unit 36.
  • the reconstructed image generation unit 64 includes a second element data acquisition unit 74 and an image reconstruction unit 76.
  • the second element data acquisition unit 74 reads the second element data from the element data stored in the element data storage unit 22 and supplies the second element data to the image reconstruction unit 76.
  • the image reconstruction unit 76 is a part that reconstructs an image of the region of interest ROI using the second element data based on the optimum sound velocity value.
  • the image reconstruction unit 76 performs reception focus processing on the second element data supplied from the second element data acquisition unit 74 based on the optimum sound speed value supplied from the optimum sound speed calculation unit 72, and outputs the sound ray signal.
  • a B-mode image signal of the region of interest ROI is generated from the sound ray signal. Further, the generated B-mode image signal is subjected to raster conversion and various necessary image processing such as gradation processing is performed to generate a reconstructed image.
  • the image reconstruction unit 76 supplies the generated reconstructed image to the image reconstruction unit 26.
  • the region of interest is set in the ultrasound image, and the optimum sound speed value is obtained in the region of interest, so that the image quality of the region of interest, that is, the tissue or lesion to be viewed is obtained.
  • the optimum sound speed value can be obtained in a short time.
  • the focus of interest set by the operator is not in focus, the received data in the focus of interest is greatly distorted, and an optimal sound speed value may not be obtained. For this reason, even if an ultrasonic image is generated using the obtained sound velocity value, the image quality of the region of interest may not be sufficiently improved.
  • the present invention sets a second transmission focus condition different from the first transmission focus condition at the time of acquiring the first element data for generating the ultrasonic image, and performs the second transmission.
  • the second element data output by transmission based on the focus condition is acquired, and the optimum sound speed value of the attention area is calculated using the second element data corresponding to the attention area. Therefore, focus on the attention area.
  • the image reconstruction unit 76 is configured to reconstruct the image of the region of interest ROI based on the optimum sound speed value.
  • the present invention is not limited to this and is based on the optimum sound speed value.
  • an image of a region (reconstruction region) that includes the region of interest ROI and is wider than the region of interest ROI may be reconstructed.
  • a region obtained by adding a region having a predetermined width to the edge of the region of interest ROI is used as a reconstructed region, and an image is reconstructed from the second element data for this reconstructed region based on the optimum sound velocity value. It is good also as a structure.
  • the image regeneration unit 26 is a part that regenerates an ultrasound image by combining the ultrasound image with the reconstructed image supplied from the image reconstruction unit 68. Specifically, the image regenerator 26 reads out the ultrasonic image stored in the image memory 52, acquires the reconstructed image supplied from the image reconstructor 68, and focuses on the region of interest ROI of the ultrasonic image. Is replaced with a reconstructed image, and a new ultrasonic image is generated. The image regeneration unit 26 supplies the generated new ultrasonic image to the display control unit 32.
  • the image regenerator 26 is not limited to the configuration in which the image of the region of interest ROI of the ultrasonic image is replaced with the reconstructed image, and for example, the luminance value of each pixel of the image of the region of interest ROI of the ultrasonic image.
  • the brightness value of each pixel corresponding to the reconstructed image is synthesized at a predetermined ratio to obtain the brightness value of each pixel, and the obtained image is used as an image of the region of interest ROI to generate a new ultrasonic image. Also good.
  • the control unit 36 controls each unit of the ultrasonic diagnostic apparatus based on a command input from the operation unit 38 by the operator.
  • the control unit 36 supplies information on the region of interest ROI input from the operation unit 38 to the region of interest setting unit 24 when the operator inputs from the operation unit 38 to set the region of interest ROI.
  • the operation unit 38 is for an operator to perform an input operation, and can be formed from a keyboard, a mouse, a trackball, a touch panel, or the like.
  • the operation unit 38 includes an input device for an operator to input information on the region of interest ROI.
  • the storage unit 40 stores an operation program and the like, and a recording medium such as a hard disk, a flexible disk, an MO, an MT, a RAM, a CD-ROM, and a DVD-ROM can be used.
  • the phasing addition unit 44, the signal processing unit 46, the DSC 48, the image processing unit 50, the display control unit 32, the optimum sound speed acquisition unit 62, and the reconstructed image generation unit 64 cause the CPU and the CPU to perform various processes. However, they may be composed of digital circuits.
  • the image reconstruction unit 76 that generates the reconstructed image and the image generation unit 18 that generates the ultrasonic image are configured as separate parts.
  • the image generation unit 18 may also serve as an image reconstruction unit. That is, after the optimum sound speed calculation unit 72 calculates the optimum sound speed value of the region of interest ROI, the phasing addition unit 44 of the image generation unit 18 receives the second element data based on the optimum sound speed value of the region of interest as a reception focus.
  • a sound ray signal is generated by performing processing, the signal processing unit 46 generates a B-mode image signal from the sound ray signal, the DSC 48 raster-converts the B-mode image signal, and the image processing unit 50 performs image processing.
  • the reconstructed image may be generated.
  • the second element data is stored in the element data storage unit 22, and the reconstructed image generation unit 64 reads the stored second element data to reconstruct the image of the region of interest.
  • the present invention is not limited to this, and the element data storage unit 22 stores the first element data, and the reconstructed image generation unit 64 reads the stored first element data to The image may be reconstructed.
  • the operation of the ultrasonic diagnostic apparatus 10 will be specifically described with reference to the flowchart of FIG.
  • the operator abuts the ultrasonic probe 12 on the surface of the subject and starts measurement
  • ultrasonic waves are generated from the transducer array 42 based on the first transmission focus condition according to the drive signal supplied from the transmission circuit 14.
  • the beam is transmitted, the ultrasonic echo from the subject is received by the transducer array 42, and the first element data is output.
  • the reception circuit 16 amplifies the analog first element data and supplies the amplified first element data to the A / D conversion unit 20, and the A / D conversion unit 20 converts the analog first element data into digital and converts it to an image generation unit. 18 to the phasing adder 44 and to the element data storage unit 22.
  • the phasing addition unit 44 of the image generation unit 18 performs reception focus processing on the first element data to generate reception data (sound ray signal) and supplies it to the signal processing unit 46.
  • the signal processing unit 46 processes the sound ray signal and generates a B-mode image signal.
  • the DSC 48 performs raster conversion on the B-mode image signal, and the image processing unit 50 performs image processing, thereby generating an ultrasonic image.
  • the generated ultrasonic image is stored in the image memory 52, and the ultrasonic image is displayed on the display unit 34 by the display control unit 32 (S102).
  • the operator operates the operation unit 38 to input a setting instruction for the region of interest ROI.
  • the region-of-interest setting unit 24 sets the region of interest ROI according to an input instruction from the operation unit 38 (S104).
  • the second transmission condition determination unit 60 determines the second transmission focus condition based on the set information of the region of interest ROI and supplies it to the control unit 36 (S106).
  • the control unit 36 supplies the second transmission focus condition to the transmission circuit 14, and the transmission circuit 14 focuses on the subject based on the second transmission focus condition.
  • the transducer array 42 is driven so as to transmit ultrasonic waves to the region.
  • the transducer array 42 receives ultrasonic echoes from the subject and outputs second element data.
  • the receiving circuit 16 amplifies the analog second element data and supplies the amplified second element data to the A / D converter 20, and the A / D converter 20 converts the analog second element data to digital to obtain the optimum sound speed. It supplies to the 2nd element data acquisition part 70 of the part 62, and it supplies to the element data storage part 22 (S108).
  • the optimum sound speed calculation unit 72 changes the set sound speed v from 1400 m / s to 1650 m / s in increments of 50 m / s using the second element data acquired by the second element data acquisition unit 70, and At the set speed v, reception focus processing is performed to generate a sound ray signal, an ultrasonic image of the region of interest ROI is formed from the sound ray signal, and the sharpness of the image of the region of interest ROI at each set sound velocity v is calculated. (S110 to S116).
  • the sharpness values of the images at the respective set sound speeds v are compared, the set sound speed v having the highest sharpness value obtained is set as the optimum sound speed value V (optimal sound speed value V), and the reconstructed image generation unit 64 It supplies to the image reconstruction part 76 (S118).
  • the second element data acquisition unit 74 of the reconstructed image generation unit 64 reads the second element data stored in the element data storage unit 22 and sends it to the image reconstruction unit 76.
  • the image reconstruction unit 76 generates a sound ray signal by performing reception focus processing on the second element data based on the optimum sound velocity value V, and generates an image (reconstructed image) of the region of interest ROI from the sound ray signal.
  • the image is formed and supplied to the image regeneration unit 26 (S120).
  • the image regenerator 26 reads out an ultrasonic image from the image memory 52, replaces the region of interest ROI of the ultrasonic image with a reconstructed image, and generates a new ultrasonic image (S122).
  • the ultrasonic diagnostic imaging apparatus 10 that performs the ultrasonic image generation method of the present invention differs from the first transmission focus condition when acquiring the first element data for generating the ultrasonic image.
  • 2 transmission focus conditions are set, second element data output by transmission based on the second transmission focus condition is acquired, and the optimum sound speed of the attention area is obtained using the second element data corresponding to the attention area. Calculate the value. Accordingly, it is possible to focus on the region of interest, and to obtain a more accurate optimum sound speed value in the region of interest, thereby obtaining an ultrasonic image with good image quality of the region of interest.
  • the ultrasonic diagnostic imaging apparatus 10 in the illustrated example when the image of the region of interest ROI is reconstructed based on the obtained optimum sound speed value V, the second sound speed obtained for calculating the optimum sound speed value V is used. Element data was used.
  • the present invention is not limited to this, and based on the obtained optimum sound velocity value V, an ultrasonic beam focused in the region of interest ROI is transmitted again to reconstruct an image of the region of interest ROI. It is good also as a structure which newly acquires the element data for doing.
  • FIG. 4 is a block diagram conceptually showing another example of an ultrasonic diagnostic imaging apparatus that implements the ultrasonic image generation method of the present invention.
  • the ultrasound diagnostic apparatus 100 illustrated in FIG. 4 includes the third transmission condition determination unit 102, and includes the reconstruction image generation unit 104 instead of the reconstruction image generation unit 64. Therefore, the same parts are denoted by the same reference numerals, and different parts are mainly described below.
  • the ultrasonic diagnostic imaging apparatus 100 includes an ultrasonic probe 12, a transmission circuit 14 and a reception circuit 16 connected to the ultrasonic probe 12, an A / D conversion unit 20, an image generation unit 18, and an element data storage unit 22.
  • the third transmission condition determination unit 102 acquires the optimum sound speed value calculated by the optimum sound speed calculation unit 72, and transmits the ultrasonic beam focused in the region of interest ROI based on the optimum sound speed value. This is a part for determining the transmission focus condition. Specifically, the third transmission condition determining unit 60 sets and sets a plurality of focal points in the attention area ROI according to the set position and size of the attention area ROI based on the optimum sound speed value. A transmission delay pattern for transmitting the ultrasonic beam to each focus is determined as a third transmission focus condition.
  • the distance between the focal points under the third transmission focus condition may be the same as or different from the distance between the focal points under the second transmission focus condition.
  • the third transmission condition determination unit 102 may be configured to determine a transmission numerical aperture, a transmission apodization, and a transmission waveform as transmission conditions in order to focus on the region of interest. The third transmission condition determination unit 102 supplies the determined third transmission focus condition to the control unit 36.
  • the reconstructed image generation unit 104 is a part that reconstructs the image of the region of interest based on the optimum sound speed value under the control of the control unit 36.
  • the reconstructed image generation unit 104 includes a third element data acquisition unit 106 and an image reconstruction unit 76.
  • the transmission circuit 14 drives the transducer array 42 based on the third transmission focus condition determined by the third transmission condition determination unit 102, and the transducer array 42 transmits an ultrasonic echo. This is a part for acquiring the third element data obtained by reception.
  • the third element data acquisition unit 106 supplies the acquired third element data to the image reconstruction unit 76.
  • the image reconstruction unit 76 reconstructs the image of the region of interest ROI using the third element data based on the optimum sound velocity value, and supplies the reconstructed image to the image regeneration unit 26.
  • an ultrasonic beam is transmitted from the transducer array 42 based on the first transmission focus condition, and the ultrasonic wave from the subject is transmitted.
  • the transducer array 42 receives the echo and outputs the first element data.
  • the reception circuit 16 amplifies the analog first element data, and the A / D conversion unit 20 converts the analog first element data into digital and supplies the digital first element data to the phasing addition unit 44 of the image generation unit 18.
  • the data is supplied to the element data storage unit 22.
  • the phasing addition unit 44 of the image generation unit 18 performs reception focus processing on the first element data to generate reception data (sound ray signal) and supplies it to the signal processing unit 46.
  • the signal processing unit 46 processes the sound ray signal and generates a B-mode image signal.
  • the DSC 48 performs raster conversion on the B-mode image signal, and the image processing unit 50 performs image processing, thereby generating an ultrasonic image.
  • the generated ultrasonic image is stored in the image memory 52, and the ultrasonic image is displayed on the display unit 34 by the display control unit 32 (S102).
  • the operator operates the operation unit 38 to input a setting instruction for the region of interest ROI.
  • the region-of-interest setting unit 24 sets the region of interest ROI according to an input instruction from the operation unit 38 (S104).
  • the second transmission condition determination unit 60 determines the second transmission focus condition based on the set information of the region of interest ROI and supplies it to the control unit 36 (S106).
  • the transmission circuit 14 drives the transducer array 42 so as to transmit an ultrasonic wave to the region of interest of the subject based on the second transmission focus condition.
  • the transducer array 42 receives ultrasonic echoes from the subject, outputs second element data, is amplified by the receiving circuit 16, and is converted to digital by the A / D converter 20. Is supplied to the second element data acquisition unit 70 of the optimum sound speed acquisition unit 62 and is also supplied to the element data storage unit 22 (S108).
  • the optimal sound speed calculation unit 72 uses the second element data acquired by the second element data acquisition unit 70 to variously change the set sound speed v, and forms an ultrasonic image at each set speed v. The sharpness of the image is calculated, and the set sound speed v having the highest obtained sharpness value is set as the optimum sound speed value (optimum sound speed value V). The optimum sound speed calculation unit 72 supplies the obtained optimum sound speed value V to the third transmission condition determination unit 102 and the image reconstruction unit 76 of the reconstructed image generation unit 104 (S130).
  • the third transmission condition determination unit 102 determines a third transmission focus condition for transmitting an ultrasonic wave to the region of interest ROI based on the optimal sound speed value V, and the control unit 36 (S132).
  • the transmission circuit 14 drives the transducer array 42 so as to transmit an ultrasonic wave to the region of interest of the subject based on the third transmission focus condition.
  • the transducer array 42 receives ultrasonic echoes from the subject, outputs third element data, is amplified by the receiving circuit 16, and is converted to digital by the A / D conversion unit 20. Is supplied to the third element data acquisition unit 106 of the reconstructed image generation unit and is also supplied to the element data storage unit 22 (S134).
  • the image reconstruction unit 76 generates a sound ray signal by performing reception focus processing on the third element data based on the optimum sound velocity value V, and generates an image (reconstructed image) of the region of interest ROI from the sound ray signal.
  • the image is formed and supplied to the image regenerator 26 (S136).
  • the image regenerator 26 reads out an ultrasonic image from the image memory 52, replaces the region of interest ROI of the ultrasonic image with a reconstructed image, and generates a new ultrasonic image (S122).
  • the element data is acquired under the second transmission focus condition different from the ultrasonic transmission focus condition for generating the ultrasonic image, and the optimum sound velocity value of the region of interest is acquired. Further, based on the optimum sound velocity value, a third transmission focus condition focused on the region of interest ROI is set, and the third element data output by transmission based on the third transmission focus condition And the image of the region of interest is reconstructed.
  • the element data when the image is reconstructed becomes more accurate, so that an accurate optimum sound speed value can be obtained in the region of interest, and an ultrasonic image having a better image quality of the region of interest is obtained. be able to.
  • the second transmission focus condition is determined in order to obtain the second element data for calculating the optimum sound velocity value.
  • ultrasonic waves are transmitted and received.
  • the present invention is not limited to this, and transmission / reception based on the second transmission focus condition may be performed to obtain the second element data before setting the region of interest ROI.
  • FIG. 6 is a block diagram conceptually showing another example of an ultrasonic diagnostic imaging apparatus that implements the ultrasonic image generation method of the present invention.
  • the ultrasonic diagnostic apparatus 120 illustrated in FIG. 6 has an optimal sound speed acquisition unit 122 instead of the optimal sound speed acquisition unit 62 and does not include the second transmission condition determination unit 60. Therefore, the same parts are denoted by the same reference numerals, and different parts are mainly described below.
  • the ultrasonic diagnostic imaging apparatus 120 includes an ultrasonic probe 12, a transmission circuit 14 and a reception circuit 16 connected to the ultrasonic probe 12, an A / D conversion unit 20, an image generation unit 18, and an element data storage unit 22.
  • the transmission circuit 14 drives the transducer array 42 so as to form an ultrasonic beam in accordance with a first transmission focus condition stored in advance in order to generate an ultrasonic image.
  • the transmitter circuit 14 forms an ultrasonic beam so as to form an ultrasonic beam according to the second transmission focus condition stored in advance in order to calculate the optimum sound velocity value.
  • the second transmission focus condition is set to perform finer transmission focus than the first transmission focus condition.
  • the optimum sound speed acquisition unit 122 is a part that acquires the optimum sound speed value of the set region of interest ROI under the control of the control unit 36.
  • the optimum sound speed acquisition unit 122 includes a second element data acquisition unit 130 and an optimum sound speed calculation unit 72.
  • the second element data acquisition unit 130 acquires information on the region of interest ROI from the region of interest setting unit 24, and the element at the position corresponding to the region of interest ROI from the second element data stored in the element data storage unit 22. Data is read out and supplied to the optimum sound speed calculator 72.
  • an ultrasonic beam is transmitted from the transducer array 42 based on the first transmission focus condition, and the ultrasonic wave from the subject is transmitted.
  • the transducer array 42 receives the echo and outputs the first element data.
  • the reception circuit 16 amplifies the analog first element data, and the A / D conversion unit 20 converts the analog first element data into digital and supplies the digital first element data to the phasing addition unit 44 of the image generation unit 18. At the same time, the data is supplied to the element data storage unit 22 (S150).
  • an ultrasonic beam is transmitted from the transducer array 42 based on the second transmission focus condition, and an ultrasonic echo from the subject is vibrated.
  • the child array 42 receives and outputs the second element data.
  • the reception circuit 16 amplifies the analog second element data, and the A / D conversion unit 20 converts the analog second element data into digital and supplies the digital second element data to the phasing addition unit 44 of the image generation unit 18. At the same time, the data is supplied to the element data storage unit 22 (S152).
  • the phasing addition unit 44 of the image generation unit 18 performs reception focus processing on the first element data to generate reception data (sound ray signal), and supplies the reception data (sound ray signal) to the signal processing unit 46.
  • the signal processing unit 46 processes the sound ray signal and generates a B-mode image signal.
  • the DSC 48 performs raster conversion on the B-mode image signal, and the image processing unit 50 performs image processing, thereby generating an ultrasonic image.
  • the generated ultrasonic image is stored in the image memory 52, and the display control unit 32 displays the ultrasonic image on the display unit 34 (S154).
  • the operator operates the operation unit 38 to input a setting instruction for the region of interest ROI.
  • the region-of-interest setting unit 24 sets the region of interest ROI according to an input instruction from the operation unit 38 (S104).
  • the second element data acquisition unit 130 corresponds to the region of interest ROI from the second element data stored in the element data storage unit 22 based on the information on the region of interest ROI.
  • the element data of the position is read and supplied to the optimum sound speed calculation unit 72 (S156).
  • the optimum sound speed calculation unit 72 changes the set sound speed v in various ways using the second element data of the region of interest ROI acquired by the second element data acquisition unit 130, and at each set speed v, converts the ultrasonic image. Then, the sharpness of the image is calculated, the set sound speed v having the highest obtained sharpness value is set as the optimal sound speed value (optimal sound speed value V), and the image reconstruction unit 76 of the reconstructed image generation unit 64 (S130).
  • the second element data acquisition unit 74 of the reconstructed image generation unit 64 reads the second element data stored in the element data storage unit 22 and sends it to the image reconstruction unit 76.
  • the image reconstruction unit 76 generates a sound ray signal by performing reception focus processing on the second element data based on the optimum sound velocity value V, and generates an image (reconstructed image) of the region of interest ROI from the sound ray signal.
  • the image is formed and supplied to the image regeneration unit 26 (S120).
  • the image regenerator 26 reads out an ultrasonic image from the image memory 52, replaces the region of interest ROI of the ultrasonic image with a reconstructed image, and generates a new ultrasonic image (S122).
  • the attention area ROI is set to correspond to the attention area ROI. Even when the second device data is acquired and the optimum sound velocity value is calculated, an accurate optimum sound velocity value can be obtained in the region of interest, and an ultrasonic image with good image quality in the region of interest can be obtained. Obtainable.
  • the present invention is basically as described above. Although the present invention has been described in detail above, the present invention is not limited to the above-described embodiment, and it is needless to say that various improvements and modifications may be made without departing from the gist of the present invention.
  • SYMBOLS 10 100, 120 Ultrasonic diagnostic apparatus 12 Ultrasonic probe 14 Transmission circuit 16 Reception circuit 18 Image generation part 20 A / D conversion part 22 Element data storage part 24 Area of interest setting part 26 Image regeneration part 32 Display control part 34 Display Unit 36 control unit 38 operation unit 40 storage unit 42 transducer array 44 phasing addition unit 46 signal processing unit 48 DSC DESCRIPTION OF SYMBOLS 50 Image processing part 52 Image memory 54 1st element data acquisition part 60 2nd transmission condition determination part 62,122 Optimal sound speed acquisition part 64,104 Reconstructed image generation part 70,74,130 2nd element data acquisition part 72 Optimal sound speed Calculation unit 76 Image reconstruction unit 102 Third transmission condition determination unit 106 Third element data acquisition unit

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WO2016204447A1 (fr) * 2015-06-16 2016-12-22 삼성메디슨 주식회사 Dispositif à ultrasons et son procédé de fonctionnement
JP7033430B2 (ja) * 2017-10-19 2022-03-10 富士フイルムヘルスケア株式会社 超音波撮像装置、および、超音波撮像方法
KR20190128894A (ko) * 2018-05-09 2019-11-19 삼성메디슨 주식회사 초음파 영상 장치 및 그의 제어 방법

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