[go: up one dir, main page]

WO2013038424A3 - Process for purifying diacerein - Google Patents

Process for purifying diacerein Download PDF

Info

Publication number
WO2013038424A3
WO2013038424A3 PCT/IN2012/000464 IN2012000464W WO2013038424A3 WO 2013038424 A3 WO2013038424 A3 WO 2013038424A3 IN 2012000464 W IN2012000464 W IN 2012000464W WO 2013038424 A3 WO2013038424 A3 WO 2013038424A3
Authority
WO
WIPO (PCT)
Prior art keywords
formula
diacerein
compound
purifying
silylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2012/000464
Other languages
French (fr)
Other versions
WO2013038424A2 (en
Inventor
Milind Gharpure
Dnyandev Rane
Manish Chandrakant SHUKLA
Pramod Vitthal PATIL
Girish Tilakchand PATLE
Sachin Mahadeo LAD
Deepak B. BAVISKAR
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glenmark Generics Ltd
Original Assignee
Glenmark Generics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Ltd filed Critical Glenmark Generics Ltd
Publication of WO2013038424A2 publication Critical patent/WO2013038424A2/en
Publication of WO2013038424A3 publication Critical patent/WO2013038424A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention provides a process for purification of diacerein, compound of Formula I, the process comprising a. reacting diacerein, compound of Formula I with a silylating agent to form a compound of Formula II, silylated diacerein wherein R is alkyl; and [Formula (I)] [Formula (II)] b. deprotecting compound of Formula II, silylated diacerein in presence of a polar solvent.
PCT/IN2012/000464 2011-07-13 2012-06-29 Process for purifying diacerein Ceased WO2013038424A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2013MU2011 2011-07-13
IN2013/MUM/2011 2011-07-13

Publications (2)

Publication Number Publication Date
WO2013038424A2 WO2013038424A2 (en) 2013-03-21
WO2013038424A3 true WO2013038424A3 (en) 2013-05-10

Family

ID=47883865

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000464 Ceased WO2013038424A2 (en) 2011-07-13 2012-06-29 Process for purifying diacerein

Country Status (1)

Country Link
WO (1) WO2013038424A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096276A1 (en) * 2000-06-13 2001-12-20 Synteco S.P.A. A process for the purification of diacerein
WO2004050601A2 (en) * 2002-11-29 2004-06-17 Synteco S.P.A. Process for purifying diacerein
KR20080102804A (en) * 2007-05-22 2008-11-26 주식회사 엔지켐 Method for Purifying Diacerane

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096276A1 (en) * 2000-06-13 2001-12-20 Synteco S.P.A. A process for the purification of diacerein
WO2004050601A2 (en) * 2002-11-29 2004-06-17 Synteco S.P.A. Process for purifying diacerein
KR20080102804A (en) * 2007-05-22 2008-11-26 주식회사 엔지켐 Method for Purifying Diacerane

Also Published As

Publication number Publication date
WO2013038424A2 (en) 2013-03-21

Similar Documents

Publication Publication Date Title
IN2014MN02496A (en)
TN2014000415A1 (en) Novel thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof
EP3388426A3 (en) Compounds for protection of cells
WO2012004396A3 (en) Process of preparing a thrombin specific inhibitor
PH12015500008A1 (en) Dimethyl-benzoic acid compounds
WO2010089055A3 (en) Use of sulfurous, heteroaromatic acid analogs as bactericides
IN2014CN04449A (en)
WO2011142825A3 (en) Novel sulfur containing compounds
EA201490998A1 (en) METHOD OF OBTAINING COMPLEX ETHERS (5-FLUOR-2-METHYL-3-QUINOLIN-2-ILMETHIL-INDOL-1-IL) -CATTY ACID
WO2011153423A3 (en) Processes and intermediates
WO2010004578A3 (en) Novel and improved processes for the preparation of paliperidone
MY164880A (en) Process for the preparation of isoxazolyl-methoxy-nicotinic acids
IN2014MN00850A (en)
WO2014087208A3 (en) A process of preparing alcaftadine
WO2014068333A3 (en) New process
WO2012140490A3 (en) Processes for preparing pitavastatin calcium
SG194727A1 (en) Method for modification of organic molecules
MY156704A (en) Process for preparing silicon-containing azo-dicarbamides
MX2013000294A (en) Intermediates and process for preparing a thrombin specific inhibitor.
MX2010009926A (en) New process for the preparatiion of cyclohexanecarboxylic acid dericatives.
WO2012164242A8 (en) Process for the preparation of paliperidone
AU2013237020A8 (en) Sulphonamide derivatives of benzylamine for the treatment of CNS diseases
WO2013038424A3 (en) Process for purifying diacerein
WO2011108009A3 (en) Process for the preparation of fampridine
WO2012012391A3 (en) Process for preparing pyrano - [2,3-c]pyridine derivatives

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12832338

Country of ref document: EP

Kind code of ref document: A2